cytosine has been researched along with Blast Crisis in 3 studies
Blast Crisis: An advanced phase of chronic myelogenous leukemia, characterized by a rapid increase in the proportion of immature white blood cells (blasts) in the blood and bone marrow to greater than 30%.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the toxicity profile, activity, and pharmacokinetics of a novel L-nucleoside analog, troxacitabine (BCH-4556), in patients with advanced leukemia." | 9.09 | Troxacitabine, a novel dioxolane nucleoside analog, has activity in patients with advanced leukemia. ( Baker, SD; Beran, M; Bivins, C; Cortes, JE; Giles, FJ; Jolivet, J; Kantarjian, HM; O'Brien, S; Smith, TL; Thomas, DA, 2001) |
| "To investigate the toxicity profile, activity, and pharmacokinetics of a novel L-nucleoside analog, troxacitabine (BCH-4556), in patients with advanced leukemia." | 5.09 | Troxacitabine, a novel dioxolane nucleoside analog, has activity in patients with advanced leukemia. ( Baker, SD; Beran, M; Bivins, C; Cortes, JE; Giles, FJ; Jolivet, J; Kantarjian, HM; O'Brien, S; Smith, TL; Thomas, DA, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alvarado, Y | 1 |
| Kantarjian, HM | 2 |
| Cortes, JE | 2 |
| Apostolidou, E | 1 |
| Bivins, C | 2 |
| Giles, FJ | 2 |
| Fajkusová, L | 1 |
| Fajkus, J | 1 |
| Polácková, K | 1 |
| Fulnecek, J | 1 |
| Dvoráková, D | 1 |
| Krahulcová, E | 1 |
| Baker, SD | 1 |
| Thomas, DA | 1 |
| O'Brien, S | 1 |
| Smith, TL | 1 |
| Beran, M | 1 |
| Jolivet, J | 1 |
2 trials available for cytosine and Blast Crisis
| Article | Year |
|---|---|
Troxacitabine activity in extramedullary myeloid leukemia.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Cytosine; Dioxolanes; Fem | 2002 |
Troxacitabine, a novel dioxolane nucleoside analog, has activity in patients with advanced leukemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Agents; Blast Crisis; Cytosine; Dioxolanes; Dose-Response | 2001 |
1 other study available for cytosine and Blast Crisis
| Article | Year |
|---|---|
Detailed mapping of methylcytosine positions at the CpG island surrounding the Pa promoter at the bcr-abl locus in CML patients and in two cell lines, K562 and BV173.
Topics: Base Sequence; Blast Crisis; Chromosomes, Human, Pair 22; Chromosomes, Human, Pair 9; Cytosine; Dinu | 2000 |