Page last updated: 2024-10-17

cytosine and Arthritis, Rheumatoid

cytosine has been researched along with Arthritis, Rheumatoid in 10 studies

Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.

Research Excerpts

ExcerptRelevanceReference
"The influence of the polymorphism of the estrogen receptor-beta gene, cytosine-adenine (CA) dinucleotide repeat in intron 6, in the occurrence of rheumatoid arthritis (RA) was investigated."7.76Association of cytosine-adenine repeat polymorphism of the estrogen receptor-beta gene with rheumatoid arthritis symptoms. ( González-Canga, A; Negishi, E; Okuzawa, H; Suzuki, M; Ueno, K; Ugai, K, 2010)
"The influence of the polymorphism of the estrogen receptor-beta gene, cytosine-adenine (CA) dinucleotide repeat in intron 6, in the occurrence of rheumatoid arthritis (RA) was investigated."3.76Association of cytosine-adenine repeat polymorphism of the estrogen receptor-beta gene with rheumatoid arthritis symptoms. ( González-Canga, A; Negishi, E; Okuzawa, H; Suzuki, M; Ueno, K; Ugai, K, 2010)
"Sjogren's syndrome is characterized by T-cell infiltration of exocrine glands leading to parenchymal destruction and impaired glandular function."1.40Th1 and Th2 polymorphisms in Sjögren's syndrome and rheumatoid arthritis. ( de Albuquerque Tavares Carvalho, A; de Souza, TR; Duarte, ÂP; Gueiros, LA; Leão, JC; Porter, SR, 2014)
"Rheumatoid and juvenile idiopathic arthritis (RA, JIA) are chronic inflammatory arthropathies with polygenic autoimmune background."1.33Polymorphisms in the interleukin-4 and IL-4 receptor genes modify risk for chronic inflammatory arthropathies in women. ( Rooney, M; Suppiah, V; Vandenbroeck, K, 2006)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (20.00)18.2507
2000's4 (40.00)29.6817
2010's3 (30.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Zeng, Y1
Zhao, K1
Oros Klein, K1
Shao, X1
Fritzler, MJ1
Hudson, M1
Colmegna, I1
Pastinen, T1
Bernatsky, S1
Greenwood, CMT1
Dávila-Fajardo, CL1
Márquez, A1
Pascual-Salcedo, D2
Moreno Ramos, MJ1
García-Portales, R1
Magro, C1
Alegre-Sancho, JJ1
Balsa, A2
Cabeza-Barrera, J1
Raya, E1
Martín, J2
de Souza, TR1
de Albuquerque Tavares Carvalho, A1
Duarte, ÂP1
Porter, SR1
Leão, JC1
Gueiros, LA1
González-Canga, A1
Ugai, K1
Suzuki, M1
Okuzawa, H1
Negishi, E1
Ueno, K1
Lin, SC1
Yen, JH1
Tsai, JJ1
Tsai, WC1
Ou, TT1
Liu, HW1
Chen, CJ1
Orozco, G1
Sánchez, E1
González-Gay, MA1
López-Nevot, MA1
Torres, B1
Cáliz, R1
Ortego-Centeno, N1
Jiménez-Alonso, J1
de Pablo, R1
Nuñez-Roldan, A1
González-Escribano, MF1
Suppiah, V1
Rooney, M1
Vandenbroeck, K1
Eyre, S1
Bowes, J1
Potter, C1
Worthington, J1
Barton, A1
Brinkman, BM2
Huizinga, TW2
Breedveld, FC2
Verweij, CL2
Kurban, SS1
van der Velde, EA1
Schreuder, GM1
Hazes, JM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
"Screening Protein Predictive of Response to Tumor Necrosis Factor-α Inhibitors Treatment in Chinese Rheumatoid Arthritis From Real World and Investigating Its Mechanism Through Signal Pathway"[NCT02878161]Phase 4240 participants (Anticipated)Interventional2016-01-31Enrolling by invitation
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for cytosine and Arthritis, Rheumatoid

ArticleYear
Confirmation of -174G/C interleukin-6 gene promoter polymorphism as a genetic marker predicting antitumor necrosis factor treatment outcome.
    Pharmacogenetics and genomics, 2014, Volume: 24, Issue:1

    Topics: Adalimumab; Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Ag

2014

Other Studies

9 other studies available for cytosine and Arthritis, Rheumatoid

ArticleYear
Thousands of CpGs Show DNA Methylation Differences in ACPA-Positive Individuals.
    Genes, 2021, 08-29, Volume: 12, Issue:9

    Topics: Anti-Citrullinated Protein Antibodies; Arthritis, Rheumatoid; CpG Islands; Cytosine; Databases, Fact

2021
Th1 and Th2 polymorphisms in Sjögren's syndrome and rheumatoid arthritis.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2014, Volume: 43, Issue:6

    Topics: Adenine; Adult; Aged; Antibodies, Antinuclear; Arthritis, Rheumatoid; Autoantigens; Case-Control Stu

2014
Association of cytosine-adenine repeat polymorphism of the estrogen receptor-beta gene with rheumatoid arthritis symptoms.
    Rheumatology international, 2010, Volume: 30, Issue:9

    Topics: Adenine; Adult; Aged; Alleles; Arthritis, Rheumatoid; Case-Control Studies; Cytosine; Dinucleotide R

2010
Association of a programmed death 1 gene polymorphism with the development of rheumatoid arthritis, but not systemic lupus erythematosus.
    Arthritis and rheumatism, 2004, Volume: 50, Issue:3

    Topics: Alleles; Antigens, CD; Antigens, Surface; Apoptosis Regulatory Proteins; Arthritis, Rheumatoid; Cyto

2004
Association of a functional single-nucleotide polymorphism of PTPN22, encoding lymphoid protein phosphatase, with rheumatoid arthritis and systemic lupus erythematosus.
    Arthritis and rheumatism, 2005, Volume: 52, Issue:1

    Topics: Adult; Arthritis, Rheumatoid; Cytosine; Female; Gene Frequency; Genotype; Humans; Lupus Erythematosu

2005
Polymorphisms in the interleukin-4 and IL-4 receptor genes modify risk for chronic inflammatory arthropathies in women.
    Experimental and molecular pathology, 2006, Volume: 81, Issue:3

    Topics: Arginine; Arthritis, Juvenile; Arthritis, Rheumatoid; Case-Control Studies; Cytosine; Female; Gene F

2006
Association of the FCRL3 gene with rheumatoid arthritis: a further example of population specificity?
    Arthritis research & therapy, 2006, Volume: 8, Issue:4

    Topics: Alleles; Arthritis, Rheumatoid; Case-Control Studies; Cytosine; Epitopes; Gene Frequency; Genetic Ma

2006
Allele-specific quantification of TNFA transcripts in rheumatoid arthritis.
    Human genetics, 1996, Volume: 97, Issue:6

    Topics: Alleles; Arthritis, Rheumatoid; Base Sequence; Cells, Cultured; Cytosine; Female; HLA-DR Antigens; H

1996
Tumour necrosis factor alpha gene polymorphisms in rheumatoid arthritis: association with susceptibility to, or severity of, disease?
    British journal of rheumatology, 1997, Volume: 36, Issue:5

    Topics: Adenine; Adult; Aged; Alleles; Arthritis, Rheumatoid; Base Sequence; Case-Control Studies; Cytosine;

1997