cytosine has been researched along with Adverse Drug Event in 8 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " Secondary outcomes were toxic effects (to assess safety) and adherence to treatment (to assess feasibility)." | 2.79 | Activity, safety, and feasibility of cidofovir and imiquimod for treatment of vulval intraepithelial neoplasia (RT³VIN): a multicentre, open-label, randomised, phase 2 trial. ( Dutton, P; Fiander, A; Griffiths, G; Hibbitts, S; Hurt, CN; Jones, S; Madden, T; Man, S; Naik, R; Nordin, AJ; Powell, N; Tristram, A, 2014) |
| " No adverse events occurred that prevented dose escalation." | 2.77 | First pharmacokinetic and safety study in humans of the novel lipid antiviral conjugate CMX001, a broad-spectrum oral drug active against double-stranded DNA viruses. ( Godkin, S; Lampert, B; Painter, G; Painter, W; Robertson, A; Trost, LC, 2012) |
| "Patients with solid tumors received troxacitabine as a progressively longer infusion on days 1-4 of a 28-day cycle." | 2.73 | Phase I study of troxacitabine administered by continuous infusion in subjects with advanced solid malignancies. ( Baker, SD; Donehower, RC; Hidalgo, M; Jimeno, A; Laheru, D; Lee, CK; Ma, WW; Messersmith, WA, 2008) |
| "All patients had progressive respiratory failure with lobar consolidation with or without patchy ground glass opacity." | 1.42 | Outcomes of early administration of cidofovir in non-immunocompromised patients with severe adenovirus pneumonia. ( Hong, DJ; Jhun, BW; Kim, K; Kim, SJ; Park, SB, 2015) |
| "Nephrotoxicity is a common and often clinically relevant adverse drug reaction." | 1.37 | [Drug-drug interactions and nephrotoxicity]. ( Czock, D; Keller, F, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Uzay, A | 1 |
| Gündoğdu, Y | 1 |
| Koşan, B | 1 |
| Yetiş, T | 1 |
| Gür, H | 1 |
| Okuturlar, Y | 1 |
| Kartı, SS | 1 |
| Tristram, A | 1 |
| Hurt, CN | 1 |
| Madden, T | 1 |
| Powell, N | 1 |
| Man, S | 1 |
| Hibbitts, S | 1 |
| Dutton, P | 1 |
| Jones, S | 1 |
| Nordin, AJ | 1 |
| Naik, R | 1 |
| Fiander, A | 1 |
| Griffiths, G | 1 |
| Kim, SJ | 1 |
| Kim, K | 1 |
| Park, SB | 1 |
| Hong, DJ | 1 |
| Jhun, BW | 1 |
| Czock, D | 1 |
| Keller, F | 1 |
| Painter, W | 1 |
| Robertson, A | 1 |
| Trost, LC | 1 |
| Godkin, S | 1 |
| Lampert, B | 1 |
| Painter, G | 1 |
| Jimeno, A | 1 |
| Messersmith, WA | 1 |
| Lee, CK | 1 |
| Ma, WW | 1 |
| Laheru, D | 1 |
| Donehower, RC | 1 |
| Baker, SD | 1 |
| Hidalgo, M | 1 |
| Hanefeld, F | 1 |
| Riehm, H | 1 |
| Wegmann, T | 1 |
3 trials available for cytosine and Adverse Drug Event
| Article | Year |
|---|---|
Activity, safety, and feasibility of cidofovir and imiquimod for treatment of vulval intraepithelial neoplasia (RT³VIN): a multicentre, open-label, randomised, phase 2 trial.
Topics: Adult; Aminoquinolines; Antineoplastic Combined Chemotherapy Protocols; Carcinoma in Situ; Cidofovir | 2014 |
First pharmacokinetic and safety study in humans of the novel lipid antiviral conjugate CMX001, a broad-spectrum oral drug active against double-stranded DNA viruses.
Topics: Administration, Oral; Adolescent; Adult; Antiviral Agents; Area Under Curve; Biological Availability | 2012 |
Phase I study of troxacitabine administered by continuous infusion in subjects with advanced solid malignancies.
Topics: Adult; Aged; Cytosine; Dioxolanes; Dose-Response Relationship, Drug; Drug Administration Schedule; D | 2008 |
5 other studies available for cytosine and Adverse Drug Event
| Article | Year |
|---|---|
Daily low dose intravesical cidofovir for the treatment of BK virus associated hemorrhagic cystitis after allogeneic stem cell transplantation.
Topics: Antiviral Agents; BK Virus; Cidofovir; Cystitis; Cytosine; Drug-Related Side Effects and Adverse Rea | 2023 |
Outcomes of early administration of cidofovir in non-immunocompromised patients with severe adenovirus pneumonia.
Topics: Adenovirus Infections, Human; Adenoviruses, Human; Cidofovir; Cytosine; Drug-Related Side Effects an | 2015 |
[Drug-drug interactions and nephrotoxicity].
Topics: Aminoglycosides; Analgesics; Anti-Bacterial Agents; Anti-HIV Agents; Antineoplastic Agents; Antirheu | 2011 |
Therapy of acute lymphoblastic leukaemia in childhood: effects on the nervous system.
Topics: Asparaginase; Blood-Brain Barrier; Brain Diseases; Cyclophosphamide; Cytosine; Drug-Related Side Eff | 1980 |
[Treatment of systemic mycosis (author's transl)].
Topics: Adrenal Cortex Hormones; Antifungal Agents; Benzene Derivatives; Cytosine; Drug-Related Side Effects | 1973 |