cytosine has been researched along with Acute Myelogenous Leukemia in 56 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Daunorubicin, thioguanine and cytosine arabinoside were administered from the 17th to 34th weeks of pregnancy in a 23-year-old patient with acute myeloid leukaemia." | 7.66 | Normal infant after treatment of acute myeloid leukaemia in pregnancy with daunorubicin. ( Baikie, MJ; Campbell, SN; Lowenthal, RM; Marsden, KA; Newman, NM, 1978) |
| "Patients with refractory acute myeloid leukemia (AML), advanced myelodysplastic syndromes (MDS), or chronic myelogenous leukemia in blastic phase (CML-BP) were initially randomly assigned to receive troxacitabine 5." | 5.10 | Randomized phase I/II study of troxacitabine combined with cytarabine, idarubicin, or topotecan in patients with refractory myeloid leukemias. ( Cortes, JE; Douer, D; Estey, EH; Faderl, S; Garcia-Manero, G; Giles, FJ; Jeha, SS; Kantarjian, HM; Koller, CA; Levine, AM; O'Brien, SM; Thomas, DA, 2003) |
| "Daunorubicin, thioguanine and cytosine arabinoside were administered from the 17th to 34th weeks of pregnancy in a 23-year-old patient with acute myeloid leukaemia." | 3.66 | Normal infant after treatment of acute myeloid leukaemia in pregnancy with daunorubicin. ( Baikie, MJ; Campbell, SN; Lowenthal, RM; Marsden, KA; Newman, NM, 1978) |
| " To confirm the safety and tolerability of dosing schedules, after 20 patients had been treated in a group we enrolled an expanded cohort of 20-25 patients to that group if at least four patients had achieved complete remission or complete remission with incomplete blood count recovery, and if the 30 day death rate was 20% or less." | 2.77 | Oral sapacitabine for the treatment of acute myeloid leukaemia in elderly patients: a randomised phase 2 study. ( Arellano, M; Chiao, J; Claxton, D; Coutre, S; Faderl, S; Garcia-Manero, G; Goldberg, SL; Jabbour, E; Kantarjian, H; Luger, S; Maness, L; Plunkett, W; Schiller, G; Seiter, K; Stock, W; Strickland, SA; Venugopal, P; Wetzler, M, 2012) |
| " Its oral bioavailability and tolerable toxicity profile allow the drug to be used in an outpatient setting, especially in elderly unfit patients." | 2.58 | The efficacy of sapacitabine in treating patients with acute myeloid leukemia. ( Czemerska, M; Robak, T; Wierzbowska, A, 2018) |
| "A number of new agents in acute myeloid leukemia (AML) have held much promise in recent years, but most have failed to change the therapeutic landscape." | 2.49 | New agents: great expectations not realized. ( Lancet, JE, 2013) |
| "Prognosis of elderly patients with acute myeloid leukemia (AML) remains poor and new treatment approaches are urgently needed." | 1.42 | Sapacitabine in the treatment of acute myeloid leukemia. ( Norkin, M; Richards, AI, 2015) |
| "The incidence of acute myeloid leukemia (AML) increases with age, with a median age at diagnosis of 67 years." | 1.37 | Novel agents for the treatment of acute myeloid leukemia in the older patient. ( Baer, MR; Gojo, I, 2011) |
| "We report a rare occurrence of myeloid sarcoma in a 7 years old child with acute myeloblastic leukaemia (AML-FAB type M2)." | 1.37 | Myeloid sarcoma in a child with acute myeloblastic leukaemia. ( Ahmad, J; Hussain, G; Kausar, S; Zafar, L, 2011) |
| "Hemorrhagic cystitis is a common complication in hematopoietic stem cell transplant recipients." | 1.35 | Hyperbaric oxygen therapy in BKV-associated hemorrhagic cystitis refractory to intravenous and intravesical cidofovir: case report and review of literature. ( Benedetti, E; Ceccherini-Nelli, L; Focosi, D; Galimberti, S; Maggi, F; Papineschi, F; Petrini, M; Pistolesi, D, 2009) |
| "Patients with trisomy 21 have an increased incidence of haematological disorders, including neonatal 'leukaemoid reaction' (transient myeloproliferative disorder [TMD]), and acute leukaemias." | 1.29 | Acute myeloid leukaemia in patients with trisomy 21 (Down syndrome) treated by bone marrow transplantation. ( Dalla Pozza, L; Goleta-Dy, A; Shaw, PJ; Stevens, MM, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (23.21) | 18.7374 |
| 1990's | 4 (7.14) | 18.2507 |
| 2000's | 10 (17.86) | 29.6817 |
| 2010's | 25 (44.64) | 24.3611 |
| 2020's | 4 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Aivalioti, MM | 1 |
| Bartholdy, BA | 1 |
| Pradhan, K | 1 |
| Bhagat, TD | 1 |
| Zintiridou, A | 1 |
| Jeong, JJ | 1 |
| Thiruthuvanathan, VJ | 1 |
| Pujato, M | 1 |
| Paranjpe, A | 1 |
| Zhang, C | 1 |
| Levine, RL | 2 |
| Viny, AD | 1 |
| Wickrema, A | 1 |
| Verma, A | 2 |
| Will, B | 2 |
| Ma, C | 1 |
| Liu, P | 1 |
| Cui, S | 1 |
| Gao, C | 1 |
| Tan, X | 1 |
| Liu, Z | 1 |
| Xu, R | 1 |
| Seethy, AA | 1 |
| Pethusamy, K | 1 |
| Kushwaha, T | 1 |
| Kumar, G | 1 |
| Talukdar, J | 1 |
| Chaubey, R | 1 |
| Sundaram, UD | 1 |
| Mahapatra, M | 1 |
| Saxena, R | 1 |
| Dhar, R | 1 |
| Inampudi, KK | 1 |
| Karmakar, S | 1 |
| Papaioannou, D | 2 |
| Ozer, HG | 1 |
| Nicolet, D | 1 |
| Urs, AP | 1 |
| Herold, T | 2 |
| Mrózek, K | 1 |
| Batcha, AMN | 1 |
| Metzeler, KH | 1 |
| Yilmaz, AS | 1 |
| Volinia, S | 1 |
| Bill, M | 1 |
| Kohlschmidt, J | 1 |
| Pietrzak, M | 1 |
| Walker, CJ | 1 |
| Carroll, AJ | 1 |
| Braess, J | 1 |
| Powell, BL | 1 |
| Eisfeld, AK | 1 |
| Uy, GL | 1 |
| Wang, ES | 1 |
| Kolitz, JE | 1 |
| Stone, RM | 1 |
| Hiddemann, W | 1 |
| Byrd, JC | 2 |
| Bloomfield, CD | 1 |
| Garzon, R | 2 |
| Dogan, S | 1 |
| Cilic, A | 1 |
| Marjanovic, D | 1 |
| Kurtovic-Kozaric, A | 1 |
| Hibbert, KA | 1 |
| Shepard, JO | 1 |
| Lane, RJ | 1 |
| Azar, MM | 1 |
| Czemerska, M | 2 |
| Robak, T | 2 |
| Wierzbowska, A | 2 |
| Lai, TH | 2 |
| Mitchell, S | 1 |
| Wu, PJ | 1 |
| Orwick, S | 1 |
| Liu, C | 2 |
| Ravikrishnan, J | 1 |
| Woyach, J | 1 |
| Mims, A | 1 |
| Plunkett, W | 3 |
| Puduvalli, VK | 1 |
| Lapalombella, R | 1 |
| Sampath, D | 2 |
| Huang, H | 1 |
| Jiang, X | 1 |
| Li, Z | 1 |
| Li, Y | 2 |
| Song, CX | 1 |
| He, C | 3 |
| Sun, M | 1 |
| Chen, P | 1 |
| Gurbuxani, S | 1 |
| Wang, J | 2 |
| Hong, GM | 1 |
| Elkahloun, AG | 1 |
| Arnovitz, S | 1 |
| Szulwach, K | 1 |
| Lin, L | 1 |
| Street, C | 1 |
| Wunderlich, M | 1 |
| Dawlaty, M | 1 |
| Neilly, MB | 1 |
| Jaenisch, R | 1 |
| Yang, FC | 1 |
| Mulloy, JC | 1 |
| Jin, P | 1 |
| Liu, PP | 1 |
| Rowley, JD | 1 |
| Xu, M | 1 |
| Chen, J | 1 |
| Lancet, JE | 1 |
| Lim, MY | 1 |
| Jamieson, K | 1 |
| Aslanyan, MG | 1 |
| Kroeze, LI | 1 |
| Langemeijer, SM | 1 |
| Koorenhof-Scheele, TN | 1 |
| Massop, M | 1 |
| van Hoogen, P | 1 |
| Stevens-Linders, E | 1 |
| van de Locht, LT | 1 |
| Tönnissen, E | 1 |
| van der Heijden, A | 1 |
| da Silva-Coelho, P | 1 |
| Cilloni, D | 1 |
| Saglio, G | 1 |
| Marie, JP | 1 |
| Tang, R | 1 |
| Labar, B | 1 |
| Amadori, S | 1 |
| Muus, P | 1 |
| Willemze, R | 1 |
| Marijt, EW | 1 |
| de Witte, T | 1 |
| van der Reijden, BA | 1 |
| Suciu, S | 1 |
| Jansen, JH | 1 |
| Rampal, R | 1 |
| Alkalin, A | 1 |
| Madzo, J | 1 |
| Vasanthakumar, A | 1 |
| Pronier, E | 1 |
| Patel, J | 2 |
| Ahn, J | 1 |
| Abdel-Wahab, O | 1 |
| Shih, A | 1 |
| Lu, C | 1 |
| Ward, PS | 1 |
| Tsai, JJ | 1 |
| Hricik, T | 2 |
| Tosello, V | 1 |
| Tallman, JE | 1 |
| Zhao, X | 1 |
| Daniels, D | 1 |
| Dai, Q | 1 |
| Ciminio, L | 1 |
| Aifantis, I | 1 |
| Fuks, F | 1 |
| Tallman, MS | 1 |
| Ferrando, A | 1 |
| Nimer, S | 1 |
| Paietta, E | 2 |
| Thompson, CB | 1 |
| Licht, JD | 1 |
| Mason, CE | 2 |
| Godley, LA | 1 |
| Melnick, A | 1 |
| Figueroa, ME | 1 |
| Burnett, AK | 2 |
| Russell, N | 1 |
| Hills, RK | 2 |
| Panoskaltsis, N | 1 |
| Khwaja, A | 1 |
| Hemmaway, C | 1 |
| Cahalin, P | 1 |
| Clark, RE | 1 |
| Milligan, D | 1 |
| Chowdhury, B | 1 |
| McGovern, A | 1 |
| Cui, Y | 1 |
| Choudhury, SR | 1 |
| Cho, IH | 1 |
| Cooper, B | 1 |
| Chevassut, T | 1 |
| Lossie, AC | 1 |
| Irudayaraj, J | 1 |
| Okoye-Okafor, UC | 1 |
| Bartholdy, B | 1 |
| Cartier, J | 1 |
| Gao, EN | 1 |
| Pietrak, B | 1 |
| Rendina, AR | 1 |
| Rominger, C | 1 |
| Quinn, C | 1 |
| Smallwood, A | 1 |
| Wiggall, KJ | 1 |
| Reif, AJ | 1 |
| Schmidt, SJ | 1 |
| Qi, H | 1 |
| Zhao, H | 1 |
| Joberty, G | 1 |
| Faelth-Savitski, M | 1 |
| Bantscheff, M | 1 |
| Drewes, G | 1 |
| Duraiswami, C | 1 |
| Brady, P | 1 |
| Groy, A | 1 |
| Narayanagari, SR | 1 |
| Antony-Debre, I | 1 |
| Mitchell, K | 1 |
| Wang, HR | 1 |
| Kao, YR | 1 |
| Christopeit, M | 1 |
| Carvajal, L | 1 |
| Barreyro, L | 1 |
| Makishima, H | 1 |
| Concha, N | 1 |
| Adams, ND | 1 |
| Schwartz, B | 1 |
| McCabe, MT | 1 |
| Maciejewski, J | 1 |
| Steidl, U | 1 |
| Norkin, M | 1 |
| Richards, AI | 1 |
| Ewald, B | 1 |
| Zecevic, A | 1 |
| Sulda, M | 1 |
| Blachly, JS | 1 |
| Li, S | 1 |
| Garrett-Bakelman, FE | 1 |
| Chung, SS | 1 |
| Sanders, MA | 1 |
| Rapaport, F | 1 |
| Dillon, R | 1 |
| Vijay, P | 1 |
| Brown, AL | 1 |
| Perl, AE | 1 |
| Cannon, J | 1 |
| Bullinger, L | 1 |
| Luger, S | 2 |
| Becker, M | 1 |
| Lewis, ID | 1 |
| To, LB | 1 |
| Delwel, R | 1 |
| Löwenberg, B | 1 |
| Döhner, H | 1 |
| Döhner, K | 1 |
| Guzman, ML | 1 |
| Hassane, DC | 1 |
| Roboz, GJ | 2 |
| Grimwade, D | 1 |
| Valk, PJ | 1 |
| D'Andrea, RJ | 1 |
| Carroll, M | 1 |
| Park, CY | 1 |
| Neuberg, D | 1 |
| Levine, R | 1 |
| Melnick, AM | 1 |
| Focosi, D | 1 |
| Maggi, F | 1 |
| Pistolesi, D | 1 |
| Benedetti, E | 1 |
| Papineschi, F | 1 |
| Galimberti, S | 1 |
| Ceccherini-Nelli, L | 1 |
| Petrini, M | 1 |
| Hubacek, P | 1 |
| Keslova, P | 1 |
| Formankova, R | 1 |
| Pochop, P | 1 |
| Cinek, O | 1 |
| Zajac, M | 1 |
| Lochmanova, J | 1 |
| Stary, J | 1 |
| Sedlacek, P | 1 |
| Green, SR | 1 |
| Choudhary, AK | 1 |
| Fleming, IN | 1 |
| Kanakry, CG | 1 |
| Hess, AD | 1 |
| Gocke, CD | 1 |
| Thoburn, C | 1 |
| Kos, F | 1 |
| Meyer, C | 1 |
| Briel, J | 1 |
| Luznik, L | 1 |
| Smith, BD | 1 |
| Levitsky, H | 1 |
| Karp, JE | 1 |
| Szmigielska-Kapłon, A | 1 |
| Pluta, A | 1 |
| Grzybowska-Izydorczyk, O | 1 |
| Wolska, A | 1 |
| Craddock, C | 1 |
| Baer, MR | 1 |
| Gojo, I | 1 |
| Konstandin, N | 1 |
| Bultmann, S | 1 |
| Szwagierczak, A | 1 |
| Dufour, A | 1 |
| Ksienzyk, B | 1 |
| Schneider, F | 1 |
| Mulaw, M | 1 |
| Kakadia, PM | 1 |
| Schneider, S | 1 |
| Spiekermann, K | 1 |
| Leonhardt, H | 1 |
| Bohlander, SK | 1 |
| Ahmad, J | 1 |
| Zafar, L | 1 |
| Hussain, G | 1 |
| Kausar, S | 1 |
| Kantarjian, H | 2 |
| Faderl, S | 4 |
| Garcia-Manero, G | 2 |
| Venugopal, P | 1 |
| Maness, L | 1 |
| Wetzler, M | 1 |
| Coutre, S | 1 |
| Stock, W | 1 |
| Claxton, D | 1 |
| Goldberg, SL | 1 |
| Arellano, M | 1 |
| Strickland, SA | 1 |
| Seiter, K | 1 |
| Schiller, G | 1 |
| Jabbour, E | 1 |
| Chiao, J | 1 |
| Russell, NH | 1 |
| Giles, FJ | 2 |
| Thomas, DA | 1 |
| Cortes, JE | 1 |
| Douer, D | 1 |
| Levine, AM | 1 |
| Koller, CA | 1 |
| Jeha, SS | 1 |
| O'Brien, SM | 1 |
| Estey, EH | 1 |
| Kantarjian, HM | 3 |
| Abdulkadyrov, KM | 1 |
| Gritsaev, SV | 1 |
| Bessmel'tsev, SS | 1 |
| Martynkevich, IS | 1 |
| Tiranova, SA | 1 |
| Blinov, MN | 1 |
| Osipova, RI | 1 |
| Ravandi, F | 2 |
| Giles, F | 1 |
| Cortes, J | 2 |
| Adema, AD | 1 |
| Zuurbier, L | 1 |
| Floor, K | 1 |
| Hubeek, I | 1 |
| Kaspers, GJ | 1 |
| Albertoni, F | 1 |
| Peters, GJ | 1 |
| Ritchie, EK | 1 |
| Allen-Bard, S | 1 |
| Curcio, TJ | 1 |
| Wilkes, MA | 1 |
| Park, SL | 1 |
| Kelner, MJ | 1 |
| Feldman, EJ | 1 |
| Quintás-Cardama, A | 1 |
| Gandhi, V | 1 |
| Tokioka, M | 1 |
| Fuchimoto, T | 1 |
| Saito, K | 1 |
| Uehara, H | 1 |
| Fujiwara, E | 1 |
| Goleta-Dy, A | 1 |
| Dalla Pozza, L | 1 |
| Shaw, PJ | 1 |
| Stevens, MM | 1 |
| Lübbert, M | 1 |
| Mertelsmann, R | 1 |
| Herrmann, F | 1 |
| LoPresti, AE | 1 |
| Levine, JF | 1 |
| Munk, GB | 1 |
| Tai, CY | 1 |
| Mendel, DB | 1 |
| Larson, RA | 1 |
| Sutow, WW | 1 |
| Sullivan, MP | 1 |
| Lowenthal, RM | 1 |
| Marsden, KA | 1 |
| Newman, NM | 1 |
| Baikie, MJ | 1 |
| Campbell, SN | 1 |
| Holzschu, DL | 1 |
| Presley, HL | 1 |
| Miranda, M | 1 |
| Phaff, HJ | 1 |
| Gorin, NC | 1 |
| Stachowiak, J | 1 |
| Hirsch-Marie, F | 1 |
| David, R | 1 |
| Muller, JY | 1 |
| Jullien, AM | 1 |
| Cavalier, J | 1 |
| Salmon, C | 1 |
| Najman, A | 1 |
| Duhamel, G | 1 |
| McKay, PJ | 1 |
| Docherty, JG | 1 |
| la Ferla, G | 1 |
| Lucie, NP | 1 |
| Jehn, U | 1 |
| Knüppel, W | 1 |
| Wilmanns, W | 1 |
| Atkinson, K | 1 |
| Wells, DG | 1 |
| Clink, HM | 1 |
| Kay, HE | 1 |
| Powles, R | 2 |
| McElwain, TJ | 1 |
| Willoughby, ML | 1 |
| Ozsoylu, S | 1 |
| Hiçsönmez, G | 1 |
| Fiere, D | 1 |
| Bryon, PA | 1 |
| Martin, C | 1 |
| Revol, L | 1 |
| Fairley, GH | 1 |
| Shirakawa, S | 1 |
| Saunders, GF | 1 |
| Griffin, AC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Phase 2 Study of Oral Sapacitabine in Elderly Patients With Acute Myeloid Leukemia Previously Untreated or in First Relapse, or Previously Treated Myelodysplastic Syndromes[NCT00590187] | Phase 2 | 408 participants (Actual) | Interventional | 2007-12-31 | Completed | ||
| Clofarabine, Cytarabine and Mitoxantrone (CLAM) for Relapsed or Refractory AML[NCT02686593] | Phase 2 | 50 participants (Actual) | Interventional | 2016-02-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
10 reviews available for cytosine and Acute Myelogenous Leukemia
| Article | Year |
|---|---|
The efficacy of sapacitabine in treating patients with acute myeloid leukemia.
Topics: Aged; Antineoplastic Agents; Arabinonucleosides; Cytosine; Humans; Leukemia, Myeloid, Acute; Prognos | 2018 |
New agents: great expectations not realized.
Topics: Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Arabinonucleosides; Benzo | 2013 |
Profile of sapacitabine: potential for the treatment of newly diagnosed acute myeloid leukemia in elderly patients.
Topics: Age Factors; Aged; Antineoplastic Agents; Arabinonucleosides; Cytosine; Humans; Leukemia, Myeloid, A | 2014 |
Novel and emerging drugs for acute myeloid leukemia: pharmacology and therapeutic activity.
Topics: Adenine Nucleotides; Animals; Arabinonucleosides; Azacitidine; Benzamides; Clofarabine; Cytarabine; | 2011 |
New agents in acute myeloid leukemia and other myeloid disorders.
Topics: Antineoplastic Agents; Cyclosporine; Cytosine; Deoxycytidine; Dioxolanes; Female; Gemcitabine; Human | 2004 |
Evaluation of the L-stereoisomeric nucleoside analog troxacitabine for the treatment of acute myeloid leukemia.
Topics: Animals; Antineoplastic Agents; Cytosine; Dioxolanes; Drug Evaluation, Preclinical; Humans; Leukemia | 2007 |
Potential role of novel nucleoside analogs in the treatment of acute myeloid leukemia.
Topics: Adenine Nucleotides; Antineoplastic Agents; Arabinonucleosides; Clinical Trials as Topic; Clofarabin | 2008 |
Cytosine methylation changes during normal hematopoiesis and in acute myeloid leukemia.
Topics: Cytosine; Dinucleoside Phosphates; DNA Methylation; Gene Expression Regulation, Enzymologic; Gene Ex | 1997 |
New agents for induction and postremission therapy of acute myeloid leukemia.
Topics: Aminoglycosides; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antibod | 2001 |
Combination chemotherapy in malignant diseases.
Topics: Adult; Antineoplastic Agents; Asparaginase; Carmustine; Child; Cyclophosphamide; Cytarabine; Cytosin | 1971 |
6 trials available for cytosine and Acute Myelogenous Leukemia
| Article | Year |
|---|---|
A randomised comparison of the novel nucleoside analogue sapacitabine with low-dose cytarabine in older patients with acute myeloid leukaemia.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Cytarab | 2015 |
Oral sapacitabine for the treatment of acute myeloid leukaemia in elderly patients: a randomised phase 2 study.
Topics: Administration, Oral; Aged; Aged, 80 and over; Anemia; Arabinonucleosides; Cytosine; Disease-Free Su | 2012 |
Randomized phase I/II study of troxacitabine combined with cytarabine, idarubicin, or topotecan in patients with refractory myeloid leukemias.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Child; C | 2003 |
[Anticytosine therapy for primary myelodysplastic syndrome].
Topics: Aged; Bone Marrow; Cytosine; Disease Progression; Erythrocyte Transfusion; Female; Hematologic Agent | 2003 |
Phase I/II study of continuous-infusion troxacitabine in refractory acute myeloid leukemia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Cytosine; Dioxolanes; Female; Hum | 2007 |
Intensive maintenance treatment in acute myelogenous leukemia (AML): single institution experience of a multicenter randomized trial.
Topics: Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials | 1988 |
40 other studies available for cytosine and Acute Myelogenous Leukemia
| Article | Year |
|---|---|
PU.1-Dependent Enhancer Inhibition Separates Tet2-Deficient Hematopoiesis from Malignant Transformation.
Topics: Animals; Cell Transformation, Neoplastic; Cytosine; Dioxygenases; DNA-Binding Proteins; Enhancer Ele | 2022 |
The Identification of APOBEC3G as a Potential Prognostic Biomarker in Acute Myeloid Leukemia and a Possible Drug Target for Crotonoside.
Topics: Adenosine; APOBEC-1 Deaminase; APOBEC-3G Deaminase; Biological Products; Biomarkers; Cytidine Deamin | 2022 |
Alterations of the expression of TET2 and DNA 5-hmC predict poor prognosis in Myelodysplastic Neoplasms.
Topics: Bone Marrow; Cytosine; Dioxygenases; DNA-Binding Proteins; Humans; Leukemia, Myeloid, Acute; Myelody | 2023 |
Clinical and molecular relevance of genetic variants in the non-coding transcriptome of patients with cytogenetically normal acute myeloid leukemia.
Topics: Adult; Cytosine; Humans; Leukemia, Myeloid, Acute; Middle Aged; Mutation; Prognosis; RNA, Long Nonco | 2022 |
Detection of cytosine and CpG density in proto-oncogenes and tumor suppressor genes in promoter sequences of acute myeloid leukemia.
Topics: Base Sequence; CpG Islands; Cytosine; Genes, Tumor Suppressor; Leukemia, Myeloid, Acute; Promoter Re | 2017 |
Case 1-2018. A 39-Year-Old Woman with Rapidly Progressive Respiratory Failure.
Topics: Adenoviridae; Adenoviridae Infections; Adult; Antiviral Agents; Cidofovir; Cytosine; Diagnosis, Diff | 2018 |
HSP90 inhibition depletes DNA repair proteins to sensitize acute myelogenous leukemia to nucleoside analog chemotherapeutics.
Topics: Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Benzamides; Cell Line, Tumor; Cy | 2019 |
TET1 plays an essential oncogenic role in MLL-rearranged leukemia.
Topics: 5-Methylcytosine; Chromatin Immunoprecipitation; Chromatography, Liquid; Cytosine; DNA-Binding Prote | 2013 |
Clinical and biological impact of TET2 mutations and expression in younger adult AML patients treated within the EORTC/GIMEMA AML-12 clinical trial.
Topics: 5-Methylcytosine; Adolescent; Adult; Animals; Chlorocebus aethiops; Clinical Trials as Topic; COS Ce | 2014 |
DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia.
Topics: 5-Methylcytosine; Animals; Cell Differentiation; Cytosine; Dioxygenases; DNA-Binding Proteins; Enhan | 2014 |
The hypomethylating agent Decitabine causes a paradoxical increase in 5-hydroxymethylcytosine in human leukemia cells.
Topics: 5-Methylcytosine; Azacitidine; Catalytic Domain; Chromatography, High Pressure Liquid; CpG Islands; | 2015 |
New IDH1 mutant inhibitors for treatment of acute myeloid leukemia.
Topics: Allosteric Regulation; Allosteric Site; Animals; Cell Differentiation; Cell Line, Tumor; CpG Islands | 2015 |
Sapacitabine in the treatment of acute myeloid leukemia.
Topics: Administration, Oral; Antineoplastic Agents; Arabinonucleosides; Cytosine; Humans; Leukemia, Myeloid | 2015 |
HDAC Inhibition Induces MicroRNA-182, which Targets RAD51 and Impairs HR Repair to Sensitize Cells to Sapacitabine in Acute Myelogenous Leukemia.
Topics: Apoptosis; Arabinonucleosides; Cell Line, Tumor; Cytosine; DNA Damage; Gene Expression; HeLa Cells; | 2016 |
Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia.
Topics: Adult; Alleles; CpG Islands; Cytosine; Disease Progression; DNA Methylation; Epigenesis, Genetic; Ev | 2016 |
Hyperbaric oxygen therapy in BKV-associated hemorrhagic cystitis refractory to intravenous and intravesical cidofovir: case report and review of literature.
Topics: Administration, Intravesical; Adult; Antineoplastic Agents; Antiviral Agents; BK Virus; Cidofovir; C | 2009 |
Cytomegalovirus encephalitis/retinitis in allogeneic haematopoietic stem cell transplant recipient treated successfully with combination of cidofovir and foscarnet.
Topics: Adolescent; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Encephalitis, Viral; | 2009 |
Combination of sapacitabine and HDAC inhibitors stimulates cell death in AML and other tumour types.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Cell Death; Cell Line, | 2010 |
Early lymphocyte recovery after intensive timed sequential chemotherapy for acute myelogenous leukemia: peripheral oligoclonal expansion of regulatory T cells.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cell Separation; Cytarabine; Cytosine; | 2011 |
Epigenetic manipulation of the immune response: a novel treatment strategy in hematologic malignancies.
Topics: Antigens, Neoplasm; Chromatin; CpG Islands; Cytosine; DNA Methylation; Epigenesis, Genetic; Hematolo | 2011 |
Novel agents for the treatment of acute myeloid leukemia in the older patient.
Topics: Adenine Nucleotides; Age Factors; Aged; Antineoplastic Agents; Arabinonucleosides; Azacitidine; Clof | 2011 |
Genomic 5-hydroxymethylcytosine levels correlate with TET2 mutations and a distinct global gene expression pattern in secondary acute myeloid leukemia.
Topics: 5-Methylcytosine; Cytosine; Dioxygenases; DNA-Binding Proteins; Gene Expression Profiling; Humans; I | 2011 |
Myeloid sarcoma in a child with acute myeloblastic leukaemia.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Child; Cytosine; Daunorubicin; Etopo | 2011 |
Applicability of a "Pick a Winner" trial design to acute myeloid leukemia.
Topics: Adenine Nucleotides; Aged; Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanize | 2011 |
Improving outcomes for elderly patients with AML.
Topics: Arabinonucleosides; Cytosine; Female; Humans; Leukemia, Myeloid, Acute; Male | 2012 |
Cellular resistance against troxacitabine in human cell lines and pediatric patient acute myeloid leukemia blast cells.
Topics: Antineoplastic Agents; Catalysis; Cell Line, Tumor; Cladribine; Cytosine; Deoxycytidine; Dioxolanes; | 2006 |
[A case of successfully treated candida tropicalis with 5-fluorocytosine in a patient of APL].
Topics: Aged; Candidiasis; Cytosine; Flucytosine; Humans; Leukemia, Myeloid, Acute; Male | 1982 |
Acute myeloid leukaemia in patients with trisomy 21 (Down syndrome) treated by bone marrow transplantation.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child, Preschool; Combi | 1994 |
Successful treatment of an acyclovir- and foscarnet-resistant herpes simplex virus type 1 lesion with intravenous cidofovir.
Topics: Acyclovir; Adult; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Drug Resistance | 1998 |
Childhood cancer: the improving prognosis.
Topics: Asparaginase; Child; Cyclophosphamide; Cytosine; Daunorubicin; Doxorubicin; Drug Therapy, Combinatio | 1976 |
Normal infant after treatment of acute myeloid leukaemia in pregnancy with daunorubicin.
Topics: Adult; Cytosine; Daunorubicin; Female; Fetus; Humans; Infant, Newborn; Labor, Induced; Leukemia, Mye | 1978 |
Identification of Candida lusitaniae as an opportunistic yeast in humans.
Topics: Blood; Candida; Candidiasis; Cytosine; DNA, Fungal; Guanine; Humans; Leukemia, Myeloid, Acute; Lung; | 1979 |
[High dose combination chemotherapy followed by autologous bone marrow transplantation in a case of acute myelocytic leukemia (author's transl)].
Topics: Adult; Bone Marrow Transplantation; Cyclophosphamide; Cytosine; Drug Therapy, Combination; Humans; L | 1977 |
Carcinoma of the small intestine following treated acute myeloid leukaemia.
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytosine; Daunorubicin; Human | 1990 |
Adult acute leukaemia.
Topics: Acute Disease; Administration, Oral; Adult; Aged; Antineoplastic Agents; Cyclophosphamide; Cytarabin | 1974 |
Blood and neoplastic diseases. Acute myeloblastic leukaemia.
Topics: Adolescent; Adult; Antineoplastic Agents; Blood Transfusion; Bloodletting; Cell Count; Cyclophospham | 1974 |
Immunotherapy for acute myelogenous leukaemia.
Topics: Adult; Antineoplastic Agents; Cell Separation; Cytosine; Daunorubicin; Follow-Up Studies; Freezing; | 1973 |
A case of erythroleukemia. (di Guglielmo's syndrome).
Topics: Adolescent; Blood Transfusion; Cytosine; Female; Folic Acid; Humans; Leukemia, Erythroblastic, Acute | 1974 |
[Letter: Polychemotherapeutic treatment in acute myeloblastic leukemia].
Topics: Cytosine; Daunorubicin; Drug Synergism; Drug Therapy, Combination; Glyoxal; Humans; Leucovorin; Leuk | 1973 |
In vivo methylation of DNA in human leukocytes.
Topics: Adenine; Cytosine; DNA; Guanine; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocytes; M | 1971 |