Page last updated: 2024-10-17

cytosine and Acute Lymphoid Leukemia

cytosine has been researched along with Acute Lymphoid Leukemia in 18 studies

Research Excerpts

ExcerptRelevanceReference
"To investigate the toxicity profile, activity, and pharmacokinetics of a novel L-nucleoside analog, troxacitabine (BCH-4556), in patients with advanced leukemia."9.09Troxacitabine, a novel dioxolane nucleoside analog, has activity in patients with advanced leukemia. ( Baker, SD; Beran, M; Bivins, C; Cortes, JE; Giles, FJ; Jolivet, J; Kantarjian, HM; O'Brien, S; Smith, TL; Thomas, DA, 2001)
"A leukemic child developed recurrent herpes simplex virus lesions shortly after receiving a bone marrow transplant and while taking acyclovir."7.71Successful treatment of foscarnet-resistant herpes simplex stomatitis with intravenous cidofovir in a child. ( Bryant, P; Carapetis, J; Curtis, N; Sasadeusz, J; Waters, K, 2001)
"To investigate the toxicity profile, activity, and pharmacokinetics of a novel L-nucleoside analog, troxacitabine (BCH-4556), in patients with advanced leukemia."5.09Troxacitabine, a novel dioxolane nucleoside analog, has activity in patients with advanced leukemia. ( Baker, SD; Beran, M; Bivins, C; Cortes, JE; Giles, FJ; Jolivet, J; Kantarjian, HM; O'Brien, S; Smith, TL; Thomas, DA, 2001)
"A leukemic child developed recurrent herpes simplex virus lesions shortly after receiving a bone marrow transplant and while taking acyclovir."3.71Successful treatment of foscarnet-resistant herpes simplex stomatitis with intravenous cidofovir in a child. ( Bryant, P; Carapetis, J; Curtis, N; Sasadeusz, J; Waters, K, 2001)
"Here, we report that in T cell acute lymphoblastic leukemia (T-ALL) the MYC oncogene controls the expression of TET1 and TET2 to maintain 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) patterns, which is associated with tumor cell-specific gene expression."1.51MYC deregulates TET1 and TET2 expression to control global DNA (hydroxy)methylation and gene expression to maintain a neoplastic phenotype in T-ALL. ( Choi, JH; Lodh, A; Poole, CJ; van Riggelen, J, 2019)
"We report an infant with acute lymphoblastic leukemia who developed disseminated adenovirus infection while lymphopenic during maintenance chemotherapy 6 months following a bout of adenoviral diarrhea."1.42Successful Treatment of Disseminated Adenovirus Infection in an Infant With Acute Lymphoblastic Leukemia. ( Alcamo, AM; Grimley, MS; Mo, JQ; O'Brien, MM; Pinchasik, DE, 2015)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.56)18.2507
2000's8 (44.44)29.6817
2010's9 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Poole, CJ1
Lodh, A1
Choi, JH1
van Riggelen, J1
Cao, LL1
Liu, H1
Yue, Z1
Pei, L1
Wang, H1
Jia, M1
Qasim, W1
Gilmour, K1
Zhan, H1
Derniame, S1
McNicol, AM1
Ip, W1
Hiwarkar, P1
Veys, P1
Gaspar, HB1
Alcamo, AM1
Pinchasik, DE1
Mo, JQ1
Grimley, MS1
O'Brien, MM1
Goyal, RK1
Mussa, A1
Bertorello, N1
Porta, F1
Galletto, C1
Nicolosi, MG1
Manicone, R1
Corrias, A1
Fagioli, F1
Keohane, C1
Bacon, CL1
Moran, B1
Irvine, AD2
Smith, OP1
Zhang, J1
Yuan, B1
Zhang, F1
Xiong, L1
Wu, J1
Pradhan, S1
Wang, Y1
Nishikawa, T1
Nakashima, K1
Fukano, R1
Okamura, J1
Inagaki, J1
Guérin, M1
Lepêcheur, V1
Rachieru-Sourisseau, P1
Réguerre, Y1
Pellier, I1
Martin, L1
Hatakeyama, N1
Suzuki, N1
Kudoh, T1
Hori, T1
Mizue, N1
Tsutsumi, H1
Tobin, AM1
Cotter, M1
Kirby, B1
Bridges, B1
Donegan, S1
Badros, A1
Walden, O1
Härtel, C1
Doehn, C1
Jocham, D1
Ohyashiki, JH1
Ohyashiki, K1
Kawakubo, K1
Tauchi, T1
Shimamoto, T1
Toyama, K1
Giles, FJ1
Cortes, JE1
Baker, SD1
Thomas, DA1
O'Brien, S1
Smith, TL1
Beran, M1
Bivins, C1
Jolivet, J1
Kantarjian, HM1
González-Fraile, MI1
Cañizo, C1
Caballero, D1
Hernández, R1
Vázquez, L1
López, C1
Izarra, A1
Arroyo, JL1
de la Loma, A1
Otero, MJ1
San Miguel, JF1
Bryant, P1
Sasadeusz, J1
Carapetis, J1
Waters, K1
Curtis, N1

Trials

2 trials available for cytosine and Acute Lymphoid Leukemia

ArticleYear
Interferon-γ capture T cell therapy for persistent Adenoviraemia following allogeneic haematopoietic stem cell transplantation.
    British journal of haematology, 2013, Volume: 161, Issue:3

    Topics: Adenovirus Infections, Human; Adenoviruses, Human; Adolescent; Antigens, Viral; Antiviral Agents; Ca

2013
Troxacitabine, a novel dioxolane nucleoside analog, has activity in patients with advanced leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2001, Feb-01, Volume: 19, Issue:3

    Topics: Acute Disease; Adult; Aged; Antineoplastic Agents; Blast Crisis; Cytosine; Dioxolanes; Dose-Response

2001

Other Studies

16 other studies available for cytosine and Acute Lymphoid Leukemia

ArticleYear
MYC deregulates TET1 and TET2 expression to control global DNA (hydroxy)methylation and gene expression to maintain a neoplastic phenotype in T-ALL.
    Epigenetics & chromatin, 2019, 07-02, Volume: 12, Issue:1

    Topics: 5-Methylcytosine; Animals; Cell Line, Tumor; Cytosine; Dioxygenases; DNA; DNA Methylation; DNA-Bindi

2019
The clinical values of dysregulated DNA methylation and demethylation intermediates in acute lymphoblastic leukemia.
    Hematology (Amsterdam, Netherlands), 2019, Volume: 24, Issue:1

    Topics: 5-Methylcytosine; Adolescent; Adult; Aged; Area Under Curve; Biomarkers, Tumor; Cell Lineage; Child;

2019
Successful Treatment of Disseminated Adenovirus Infection in an Infant With Acute Lymphoblastic Leukemia.
    Journal of pediatric hematology/oncology, 2015, Volume: 37, Issue:3

    Topics: Adenovirus Infections, Human; Antiviral Agents; Cidofovir; Cytosine; Humans; Immunocompromised Host;

2015
MTHFR 677 C>T genotype and adverse outcomes in treatment of childhood ALL: is the jury in?
    Pediatric blood & cancer, 2009, Volume: 52, Issue:3

    Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Antineoplastic Agents; Child; Cytosine; Genotype;

2009
Prospective bone ultrasound patterns during childhood acute lymphoblastic leukemia treatment.
    Bone, 2010, Volume: 46, Issue:4

    Topics: Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Bone and Bones; Bone Density;

2010
Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome induced by cidofovir.
    Pediatric transplantation, 2011, Volume: 15, Issue:1

    Topics: Adenoviridae Infections; Cidofovir; Cytosine; Dermatitis, Exfoliative; Drug Eruptions; Eosinophilia;

2011
Cyclophosphamide perturbs cytosine methylation in Jurkat-T cells through LSD1-mediated stabilization of DNMT1 protein.
    Chemical research in toxicology, 2011, Nov-21, Volume: 24, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Blotting, Western; Cyclophosphamide; Cytosine; DNA (Cytosine-5-)-

2011
Successful treatment with plasma exchange for disseminated cidofovir-resistant adenovirus disease in a pediatric SCT recipient.
    Bone marrow transplantation, 2012, Volume: 47, Issue:8

    Topics: Adenovirus Infections, Human; Antiviral Agents; Child, Preschool; Cidofovir; Cytosine; Drug Resistan

2012
[Usefulness of topical cidofovir treatment for recalcitrant molluscum contagiosum in immunocompromised children].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2012, Volume: 19, Issue:11

    Topics: Administration, Topical; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Child; Ch

2012
Successful cidofovir treatment of adenovirus-associated hemorrhagic cystitis and renal dysfunction after allogenic bone marrow transplant.
    The Pediatric infectious disease journal, 2003, Volume: 22, Issue:10

    Topics: Acute Kidney Injury; Adenoviridae; Adenoviridae Infections; Bone Marrow Transplantation; Cidofovir;

2003
Successful treatment of a refractory verruca in a child with acute lymphoblastic leukaemia with topical cidofovir.
    The British journal of dermatology, 2005, Volume: 152, Issue:2

    Topics: Antiviral Agents; Child; Cidofovir; Cytosine; Female; Foot Dermatoses; Humans; Organophosphonates; P

2005
Cidofovir bladder instillation for the treatment of BK hemorrhagic cystitis after allogeneic stem cell transplantation.
    American journal of hematology, 2006, Volume: 81, Issue:7

    Topics: Administration, Intravesical; Adult; Antiviral Agents; BK Virus; Cidofovir; Cystitis; Cytosine; Hemo

2006
[Intravesical cidofovir--instillation therapy for polyomavirus-associated hemorrhagic cystitis after bone marrow transplantation].
    Der Urologe. Ausg. A, 2007, Volume: 46, Issue:5

    Topics: Administration, Intravesical; Adolescent; Antiviral Agents; Bone Marrow Transplantation; Cidofovir;

2007
The methylation status of the major breakpoint cluster region in human leukemia cells, including Philadelphia chromosome-positive cells, is linked to the lineage of hematopoietic cells.
    Leukemia, 1993, Volume: 7, Issue:6

    Topics: 5-Methylcytosine; Cytosine; DNA, Neoplasm; Granulocytes; Hematopoiesis; Hematopoietic Stem Cells; Hu

1993
Cidofovir treatment of human polyomavirus-associated acute haemorrhagic cystitis.
    Transplant infectious disease : an official journal of the Transplantation Society, 2001, Volume: 3, Issue:1

    Topics: Adolescent; Antiviral Agents; Bone Marrow Transplantation; Cidofovir; Cystitis; Cytosine; Hemorrhage

2001
Successful treatment of foscarnet-resistant herpes simplex stomatitis with intravenous cidofovir in a child.
    The Pediatric infectious disease journal, 2001, Volume: 20, Issue:11

    Topics: Acyclovir; Antiviral Agents; Bone Marrow Transplantation; Child; Cidofovir; Cytosine; Drug Resistanc

2001