cytochrome-c-t has been researched along with Mycoses* in 1 studies
1 review(s) available for cytochrome-c-t and Mycoses
| Article | Year |
|---|---|
Classical and alternative components of the mitochondrial respiratory chain in pathogenic fungi as potential therapeutic targets.
The frequency of opportunistic fungal infection has increased drastically, mainly in patients who are immunocompromised due to organ transplant, leukemia or HIV infection. In spite of this, only a few classes of drugs with a limited array of targets, are available for antifungal therapy. Therefore, more specific and less toxic drugs with new molecular targets is desirable for the treatment of fungal infections. In this context, searching for differences between mitochondrial mammalian hosts and fungi in the classical and alternative components of the mitochondrial respiratory chain may provide new potential therapeutic targets for this purpose. Topics: Adenosine Triphosphate; Cytochromes c; Drug Discovery; Electron Transport; Electron Transport Chain Complex Proteins; Fungi; Humans; Ion Channels; Mitochondria; Mitochondrial Proteins; Mycoses; Oxidoreductases; Reactive Oxygen Species; Uncoupling Protein 1 | 2011 |