cytochrome-c-t has been researched along with Circoviridae-Infections* in 1 studies
1 other study(ies) available for cytochrome-c-t and Circoviridae-Infections
| Article | Year |
|---|---|
Caspase-Dependent Apoptosis Induction via Viral Protein ORF4 of Porcine Circovirus 2 Binding to Mitochondrial Adenine Nucleotide Translocase 3.
Apoptosis is an essential strategy of host defense responses and is used by viruses to maintain their life cycles. However, the apoptotic signals involved in virus replication are poorly known. In the present study, we report the molecular mechanism of apoptotic induction by the viral protein ORF4, a newly identified viral protein of porcine circovirus type 2 (PCV2). Apoptosis detection revealed not only that the activity of caspase-3 and -9 is increased in PCV2-infected and ORF4-transfected cells but also that cytochrome Topics: Adenine Nucleotide Translocator 3; Animals; Apoptosis; Caspase 3; Caspase 9; Cell Line; Circoviridae Infections; Circovirus; Cytochromes c; HEK293 Cells; Humans; Immediate-Early Proteins; Mitochondria; RNA Interference; RNA, Small Interfering; Swine | 2018 |