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cytidine diphosphate choline and Infarction, Middle Cerebral Artery

cytidine diphosphate choline has been researched along with Infarction, Middle Cerebral Artery in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's5 (41.67)29.6817
2010's6 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ballesteros, I; Camarero, G; Cuartero, MI; Hernández-Jiménez, M; Hurtado, O; Lizasoain, I; Moraga, A; Moro, MA; Pradillo, JM; Zarruk, JG1
Agulla, J; Al-Soufi, W; Argibay, B; Blanco, M; Brea, D; Campos, F; Castillo, J; Ramos-Cabrer, P; Sobrino, T1
Alkan, T; Korfali, E; Sahin, S; Temel, SG; Tolunay, S; Tureyen, K1
Agulla, J; Argibay, B; Castillo, J; Pérez-Mato, M; Ramos-Cabrer, P1
Chen, H; Han, H; Hou, C; Li, W; Xia, Z1
Alvarez-Grech, J; Díez-Tejedor, E; Expósito-Alcaide, M; Fuentes, B; Gutiérrez-Fernández, M; Rodríguez-Frutos, B; Vallejo-Cremades, MT1
Ataus, SA; Balkan, S; Locke, KW; Onal, MZ; Ozdem, SS1
Chen, XL; Kang, QY; Liu, JX; Liu, Y; Qiu, F; Tian, YF; Zhang, PB; Zhao, JJ1
Alonso de Leciñana, M; Carceller, F; Díez-Tejedor, E; Gutiérrez, M; Roda, JM1
Alborch, E; Castillo, J; Fernández-López, D; Hurtado, O; Lizasoain, I; Morales, JR; Moro, MA; Pradillo, JM; Sobrino, T1
Clark, WM; Gammans, RE; Sabounjian, LA; Selzer, KA; Williams, BJ; Zweifler, RM1
Barrachina, M; Ferrer, I; Krupinski, J; Lozano, R; Mercadal, J; Secades, JJ1

Trials

1 trial(s) available for cytidine diphosphate choline and Infarction, Middle Cerebral Artery

ArticleYear
A randomized efficacy trial of citicoline in patients with acute ischemic stroke.
    Stroke, 1999, Volume: 30, Issue:12

    Topics: Aged; Algorithms; Cytidine Diphosphate Choline; Double-Blind Method; Female; Humans; Infarction, Middle Cerebral Artery; Logistic Models; Male; Nootropic Agents; Odds Ratio

1999

Other Studies

11 other study(ies) available for cytidine diphosphate choline and Infarction, Middle Cerebral Artery

ArticleYear
Citicoline (CDP-choline) increases Sirtuin1 expression concomitant to neuroprotection in experimental stroke.
    Journal of neurochemistry, 2013, Volume: 126, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Blotting, Western; Brain Ischemia; Cells, Cultured; Cytidine Diphosphate Choline; Drug Synergism; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Knockout; Monocytes; Naphthols; Neurons; Neuroprotective Agents; Nootropic Agents; Rats; Rats, Inbred F344; Resveratrol; Sirtuin 1; Stilbenes; Stroke

2013
In vivo theranostics at the peri-infarct region in cerebral ischemia.
    Theranostics, 2013, Volume: 4, Issue:1

    Topics: Animals; Biomarkers; Cells, Cultured; Cytidine Diphosphate Choline; HSP72 Heat-Shock Proteins; Infarction, Middle Cerebral Artery; Liposomes; Magnetic Resonance Imaging; Male; Microscopy, Fluorescence; Nanocapsules; Nootropic Agents; Optical Imaging; Proteome; Rats; Rats, Sprague-Dawley

2013
Effects of citicoline used alone and in combination with mild hypothermia on apoptosis induced by focal cerebral ischemia in rats.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2010, Volume: 17, Issue:2

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Biomarkers; Brain; Brain Infarction; Brain Ischemia; Combined Modality Therapy; Cytidine Diphosphate Choline; Disease Models, Animal; Hypothermia, Induced; Immunohistochemistry; Infarction, Middle Cerebral Artery; Male; Nerve Degeneration; Neurons; Neuroprotective Agents; Nootropic Agents; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Treatment Outcome

2010
Serial MRI study of the enhanced therapeutic effects of liposome-encapsulated citicoline in cerebral ischemia.
    International journal of pharmaceutics, 2011, Feb-28, Volume: 405, Issue:1-2

    Topics: Animals; Brain; Brain Ischemia; Cerebral Infarction; Cytidine Diphosphate Choline; Disease Models, Animal; Dose-Response Relationship, Drug; Infarction, Middle Cerebral Artery; Injections, Intraperitoneal; Injections, Intravenous; Liposomes; Magnetic Resonance Imaging; Male; Nootropic Agents; Rats; Rats, Sprague-Dawley; Stroke

2011
Simple diffusion delivery via brain interstitial route for the treatment of cerebral ischemia.
    Science China. Life sciences, 2011, Volume: 54, Issue:3

    Topics: Animals; Brain Ischemia; Cytidine Diphosphate Choline; Diffusion; Infarction, Middle Cerebral Artery; Magnetic Resonance Imaging; Male; Nootropic Agents; Rats; Rats, Sprague-Dawley

2011
CDP-choline treatment induces brain plasticity markers expression in experimental animal stroke.
    Neurochemistry international, 2012, Volume: 60, Issue:3

    Topics: Animals; Apoptosis; Biomarkers; Blotting, Western; Brain Chemistry; Brain Ischemia; Cell Proliferation; Cytidine Diphosphate Choline; Glial Fibrillary Acidic Protein; Immunohistochemistry; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Magnetic Resonance Imaging; Male; Neuronal Plasticity; Nootropic Agents; Rats; Rats, Sprague-Dawley; Stroke; Synaptophysin; Vascular Endothelial Growth Factor A

2012
The effects of citicoline and lamotrigine alone and in combination following permanent middle cerebral artery occlusion in rats.
    The International journal of neuroscience, 2004, Volume: 114, Issue:2

    Topics: Analysis of Variance; Animals; Anticonvulsants; Brain; Brain Ischemia; Cerebral Infarction; Cytidine Diphosphate Choline; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Therapy, Combination; Infarction, Middle Cerebral Artery; Lamotrigine; Male; Neurologic Examination; Random Allocation; Rats; Rats, Wistar; Statistics, Nonparametric; Tetrazolium Salts; Treatment Outcome; Triazines

2004
[Effect of citicoline on spatial learning and memory of rats after focal cerebral ischemia].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2006, Volume: 26, Issue:2

    Topics: Animals; Avoidance Learning; Cytidine Diphosphate Choline; Infarction, Middle Cerebral Artery; Male; Maze Learning; Nootropic Agents; Random Allocation; Rats; Rats, Sprague-Dawley; Spatial Behavior

2006
Effect of combined therapy with thrombolysis and citicoline in a rat model of embolic stroke.
    Journal of the neurological sciences, 2006, Sep-25, Volume: 247, Issue:2

    Topics: Animals; Brain Infarction; Cell Death; Cytidine Diphosphate Choline; Disease Models, Animal; Drug Administration Schedule; Drug Therapy, Combination; Fibrinolytic Agents; Immunohistochemistry; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Interleukin-6; Male; Neurologic Examination; Neuroprotective Agents; Rats; Rats, Long-Evans; Thrombolytic Therapy; Time Factors; Tissue Plasminogen Activator; Tumor Necrosis Factor-alpha

2006
Delayed post-ischemic administration of CDP-choline increases EAAT2 association to lipid rafts and affords neuroprotection in experimental stroke.
    Neurobiology of disease, 2008, Volume: 29, Issue:1

    Topics: Animals; Cell Fractionation; Cytidine Diphosphate Choline; Disease Models, Animal; Excitatory Amino Acid Transporter 2; Gene Expression Regulation; Glutamic Acid; Infarction, Middle Cerebral Artery; Male; Membrane Microdomains; Neuroprotective Agents; Rats; Rats, Inbred F344; Time Factors

2008
CDP-choline reduces pro-caspase and cleaved caspase-3 expression, nuclear DNA fragmentation, and specific PARP-cleaved products of caspase activation following middle cerebral artery occlusion in the rat.
    Neuropharmacology, 2002, Volume: 42, Issue:6

    Topics: Animals; Blotting, Western; Caspase 3; Caspase Inhibitors; Caspases; Cell Nucleus; Cytidine Diphosphate Choline; DNA Fragmentation; Enzyme Precursors; Female; Hydrolysis; Infarction, Middle Cerebral Artery; Injections, Intraperitoneal; Nootropic Agents; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Substrate Specificity

2002