Page last updated: 2024-08-21

cytidine diphosphate choline and Apoplexy

cytidine diphosphate choline has been researched along with Apoplexy in 67 studies

Research

Studies (67)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (1.49)18.2507
2000's21 (31.34)29.6817
2010's39 (58.21)24.3611
2020's6 (8.96)2.80

Authors

AuthorsStudies
Agarwal, A; Bhatia, R; Dwivedi, S; Garg, A; Goyal, V; Gupta, A; Rajan, R; Sharma, J; Singh, MB; Srivastava, MVP; Upadhyay, A; Vishnu, VY1
Gareri, P; Secades, JJ1
Karimulin, R; Semenenko, A1
Bhattacharya, P; Gondalia, P; Kalia, K; Pradhan, D; Raval, N; Tambe, V; Tekade, RK1
Bonfill Cosp, X; Martí-Amarista, CE; Martí-Carvajal, AJ; Martí-Fàbregas, J; Solà, I; Valli, C1
Jasielski, P; Petit, V; Piędel, F; Piwek, M; Rejdak, K; Rocka, A1
El Amrousy, D; Faheem, A; Mehrez, M; Salamah, A1
Secades, JJ3
Alvarez-Sabín, J; Jacas, C; Maisterra, O; Molina, C; Ortega, G; Quintana, M; Ribo, M; Román, GC; Santamarina, E1
Ballesteros, I; Camarero, G; Cuartero, MI; Hernández-Jiménez, M; Hurtado, O; Lizasoain, I; Moraga, A; Moro, MA; Pradillo, JM; Zarruk, JG1
Bansal, KK; Goel, D; Mitta, M; Puri, P1
Kamal, AK; Nomani, F1
Grieb, P1
Overgaard, K1
Barantsevich, ER; Bogatyryova, MD; Fokina, SB; Galkin, AS; Gusev, AO; Kovalchuk, VV; Minnullin, TI; Samus, NL; Stepanenko, MA1
Minnerup, J; Schmidt, A1
Alvarez-Sabín, J; Jacas, C; Maisterra, O; Molina, C; Quintana, M; Santamarina, E1
Ivanova, DS; Vinogradov, OI; Мushba, AV1
Chipova, DT; Farrahova, KI; Karneev, AN; Solovieva, EY1
Bai, HY; Shi, PY; Xu, LL; Yin, XX; Zhang, XM; Zhou, XC1
Alvarez-Sabín, J; Castillo, J; Díez-Tejedor, E; Martínez-Vila, E; Oudovenko, N; Ríos, J; Secades, JJ1
Bulte, JW; Cao, S; Chen, H; Jablonska, A; Janowski, M; Li, Y; Liu, D; Liu, G; Liu, H; Van Zijl, PC; Walczak, P1
Minnerup, J; Schäbitz, WR1
Saver, JL1
Clark, WM1
Cho, HJ; Kim, YJ1
Andrade-Ramos, MA; Cantu, C; Chiquete, E; Leon-Jimenez, C; Miramontes-Saldana, MJ; Ruiz-Sandoval, JL1
Botsina, AIu; Shamalov, NA; Shetova, IM1
Dávalos, A; Secades, J1
Alvarez-Sabín, J; Román, GC1
Hurtado, O; Lizasoain, I; Moro, MÁ1
Agulla, J; Argibay, B; Castillo, J; Pérez-Mato, M; Ramos-Cabrer, P1
Anisimov, KV; Efremova, NM; Shamalov, NA; Shetova, IM; Stakhovskaia, LV1
Sahota, P; Savitz, SI1
Blanco, M; Brea, D; Castillo, J; Leira, R; Pérez-Mato, M; Rodríguez-González, R; Rodríguez-Yáñez, M; Sobrino, T1
Ershov, VI1
Alvarez-Grech, J; Díez-Tejedor, E; Expósito-Alcaide, M; Fuentes, B; Gutiérrez-Fernández, M; Rodríguez-Frutos, B; Vallejo-Cremades, MT1
Galkin, AS; Gusev, AO; Koval'chuk, VV1
Altach, E; Diederich, K; Eggert, V; Frauenknecht, K; Minnerup, J; Schäbitz, WR; Schmidt, A; Schneider, BK; Sommer, CJ1
Boĭko, AN; Chubykin, VI; Glukhareva, AP; Gusev, EI; Iasamanova, AN; Kabanov, AA; Kamchatnov, PR; Kolesnikova, TI; Martynov, MIu; Shchukin, IA1
Alifirova, VM; Vaizova, OE; Vengerovskiĭ, AI; Zautner, NA1
Díez-Tejedor, E; Gutiérrez-Fernández, M; Leciñana, MA; Ramos-Cejudo, J; Roda, JM; Rodríguez-Frutos, B1
Bustamante, A; Campos, M; Garcia-Bonilla, L; Giralt, D; Montaner, J; Rosell, A1
Clark, TD; Clark, WM1
Goldstein, LB1
Hubenia, OV1
Adibhatla, RM1
Zweifler, RM1
Alvarez-Sabín, J; Castillo, J; Clark, WM; Cobo, E; Dávalos, A; López, S; Lozano, R; Mercadal, J; Secades, JJ; Sherman, D; Warach, S1
Conant, R; Schauss, AG1
Adibhatla, RM; Hatcher, JF1
Adibhatla, RM; Hatcher, JF; Tureyen, K1
Cárdenas, A; Castillo, J; Hurtado, O; Lizasoain, I; Lorenzo, P; Mallolas, J; Moro, MA; Romera, C1
Alonso-Escolano, D; Castillo, J; Hurtado, O; Lizasoain, I; Lorenzo, P; Moro, MA; Pradillo, JM; Sobrino, T1
Alonso de Leciñana, M; Carceller, F; Díez Tejedor, E; Fuentes, B; Gutiérrez, M; Roda, JM1
Meden, P; Overgaard, K1
Cárdenas, A; Castillo, J; Hurtado, O; Lizasoain, I; Morales, JR; Moro, MA; Ortego, F; Pradillo, JM; Sobrino, T1
Bankhead, C1
Dashe, JF; Gammans, R; Harnett, K; Lefkowitz, DM; Pettigrew, LC; Pullicino, P; Sabounjian, L; Schwiderski, U; Warach, S1
Fisher, M; Schaebitz, W1
Aguilar, J; Giménez, R1
Clark, WM; Sabounjian, LA; Schwiderski, UE; Wechsler, LR1
Mitka, M1
Alcázar, A; Ayuso, I; Chioua, M; González, MP; Hadjipavlou-Litina, D; Marco-Contelles, J; Monjas, L; Oset-Gasque, MJ; Rodríguez-Franco, MI; Samadi, A; Soriano, E; Sucunza, D1

Reviews

27 review(s) available for cytidine diphosphate choline and Apoplexy

ArticleYear
Citicoline: pharmacological and clinical review, 2022 update.
    Revista de neurologia, 2022, 11-30, Volume: 75, Issue:s05

    Topics: Brain Injuries, Traumatic; Cognitive Dysfunction; Cytidine Diphosphate Choline; Humans; Nootropic Agents; Stroke

2022
Citicoline for treating people with acute ischemic stroke.
    The Cochrane database of systematic reviews, 2020, 08-29, Volume: 8

    Topics: Activities of Daily Living; Acute Disease; Aged; Aged, 80 and over; Bias; Brain Ischemia; Cause of Death; Cytidine Diphosphate Choline; Humans; Middle Aged; Nootropic Agents; Randomized Controlled Trials as Topic; Recovery of Function; Stroke

2020
Application of Citicoline in Neurological Disorders: A Systematic Review.
    Nutrients, 2020, Oct-12, Volume: 12, Issue:10

    Topics: Animals; Brain Injuries, Traumatic; Cognition; Cytidine Diphosphate Choline; Dementia; Disease Models, Animal; Humans; Meta-Analysis as Topic; Nervous System Diseases; Neuralgia; Neurotransmitter Agents; Peripheral Nervous System; Stroke

2020
Citicoline: pharmacological and clinical review, 2016 update.
    Revista de neurologia, 2016, Dec-23, Volume: 63, Issue:S03

    Topics: Brain Injuries, Traumatic; Cognitive Dysfunction; Cytidine Diphosphate Choline; Disease Progression; Humans; Nootropic Agents; Stroke

2016
Neuroprotective properties of citicoline: facts, doubts and unresolved issues.
    CNS drugs, 2014, Volume: 28, Issue:3

    Topics: Animals; Brain; Brain Injuries; Brain Ischemia; Clinical Trials as Topic; Cytidine Diphosphate Choline; Humans; Neurodegenerative Diseases; Neuroprotective Agents; Stroke

2014
The effects of citicoline on acute ischemic stroke: a review.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2014, Volume: 23, Issue:7

    Topics: Brain Ischemia; Clinical Trials, Phase III as Topic; Cytidine Diphosphate Choline; Humans; Nootropic Agents; Stroke

2014
Promoting recovery from ischemic stroke.
    Expert review of neurotherapeutics, 2016, Volume: 16, Issue:2

    Topics: Axons; Brain; Brain Ischemia; Cytidine Diphosphate Choline; Erythropoietin; Granulocyte Colony-Stimulating Factor; Humans; Myelin Proteins; Neovascularization, Physiologic; Neurogenesis; Neurological Rehabilitation; Neuronal Plasticity; Nogo Proteins; Nootropic Agents; Phosphodiesterase 5 Inhibitors; Recovery of Function; Regeneration; Selective Serotonin Reuptake Inhibitors; Stem Cell Transplantation; Stroke; Stroke Rehabilitation

2016
[Phospholipids metabolism disorders in acute stroke].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2016, Volume: 116, Issue:1

    Topics: Brain Ischemia; Cell Membrane; Cerebrovascular Circulation; Cytidine Diphosphate Choline; Free Radicals; Humans; Lipid Peroxidation; Lipolysis; Neuroprotective Agents; Phosphatidylcholines; Phospholipids; Stroke

2016
Early application of citicoline in the treatment of acute stroke: A meta-analysis of randomized controlled trials.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2016, Volume: 36, Issue:2

    Topics: Aged; Cytidine Diphosphate Choline; Female; Humans; Male; Middle Aged; Nootropic Agents; Randomized Controlled Trials as Topic; Stroke

2016
Citicoline for Acute Ischemic Stroke: A Systematic Review and Formal Meta-analysis of Randomized, Double-Blind, and Placebo-Controlled Trials.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2016, Volume: 25, Issue:8

    Topics: Brain Ischemia; Cytidine Diphosphate Choline; Double-Blind Method; Female; Humans; Male; Nootropic Agents; Randomized Controlled Trials as Topic; Stroke

2016
Multifunctional actions of approved and candidate stroke drugs.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2009, Volume: 6, Issue:1

    Topics: Albumins; Animals; Antihypertensive Agents; Aspirin; Brain Ischemia; Clopidogrel; Cytidine Diphosphate Choline; Dipyridamole; Erythropoietin; Granulocyte Colony-Stimulating Factor; Humans; Hypolipidemic Agents; Neuroprotective Agents; Platelet Aggregation Inhibitors; Stroke; Ticlopidine

2009
Citicoline: update on a promising and widely available agent for neuroprotection and neurorepair.
    Reviews in neurological diseases, 2008,Fall, Volume: 5, Issue:4

    Topics: Acetylcholine; Animals; Cell Membrane; Clinical Trials as Topic; Cognition Disorders; Craniocerebral Trauma; Cytidine Diphosphate Choline; Dopamine; Fatty Acids, Nonesterified; Glaucoma; Humans; Meta-Analysis as Topic; Nerve Regeneration; Neurons; Neuroprotective Agents; Optic Neuropathy, Ischemic; Parkinson Disease; Phospholipids; Stroke

2008
Efficacy of citicoline as an acute stroke treatment.
    Expert opinion on pharmacotherapy, 2009, Volume: 10, Issue:5

    Topics: Animals; Cytidine Diphosphate Choline; Humans; Nootropic Agents; Randomized Controlled Trials as Topic; Stroke; Treatment Outcome

2009
[The use of citicoline in the acute cerebral stroke].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2009, Volume: 109, Issue:12 Suppl 2

    Topics: Animals; Cytidine Diphosphate Choline; Disease Models, Animal; Humans; Neuroprotective Agents; Stroke

2009
Citicoline preclinical and clinical update 2009-2010.
    Stroke, 2011, Volume: 42, Issue:1 Suppl

    Topics: Acute Disease; Animals; Brain Ischemia; Cytidine Diphosphate Choline; Drug Evaluation, Preclinical; Humans; Neuroprotective Agents; Nootropic Agents; Recovery of Function; Stroke

2011
Citicoline in vascular cognitive impairment and vascular dementia after stroke.
    Stroke, 2011, Volume: 42, Issue:1 Suppl

    Topics: Alzheimer Disease; Brain Ischemia; Clinical Trials as Topic; Cognition; Cytidine Diphosphate Choline; Dementia, Vascular; Humans; Neuroprotective Agents; Nootropic Agents; Recovery of Function; Stroke

2011
Neuroprotection and recovery: recent data at the bench on citicoline.
    Stroke, 2011, Volume: 42, Issue:1 Suppl

    Topics: Adenosine Triphosphate; Animals; Cell Membrane; Cytidine Diphosphate Choline; Disease-Free Survival; Humans; Neuronal Plasticity; Neuroprotective Agents; Nootropic Agents; Recovery of Function; Stroke

2011
Citicoline: pharmacological and clinical review, 2010 update.
    Revista de neurologia, 2011, Mar-14, Volume: 52 Suppl 2

    Topics: Brain Injuries; Brain Ischemia; Cerebrovascular Disorders; Clinical Trials as Topic; Cognition Disorders; Cytidine Diphosphate Choline; Humans; Learning; Memory; Stroke; Synaptic Transmission

2011
Investigational therapies for ischemic stroke: neuroprotection and neurorecovery.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2011, Volume: 8, Issue:3

    Topics: Albumins; Animals; Brain Ischemia; Cell- and Tissue-Based Therapy; Clinical Trials as Topic; Cytidine Diphosphate Choline; Embryonic Stem Cells; Granulocyte Colony-Stimulating Factor; Humans; Hypothermia, Induced; Neural Stem Cells; Neuroprotective Agents; Stroke

2011
Probably role of citicoline in stroke rehabilitation: review of the literature.
    Revista de neurologia, 2012, Feb-01, Volume: 54, Issue:3

    Topics: Animals; Clinical Trials as Topic; Cytidine Diphosphate Choline; Disabled Persons; Humans; Neuronal Plasticity; Nootropic Agents; Recovery of Function; Stroke; Stroke Rehabilitation

2012
Citicoline in pre-clinical animal models of stroke: a meta-analysis shows the optimal neuroprotective profile and the missing steps for jumping into a stroke clinical trial.
    Journal of neurochemistry, 2012, Volume: 123, Issue:2

    Topics: Animals; Clinical Trials as Topic; Cytidine Diphosphate Choline; Disease Models, Animal; Humans; Neuroprotective Agents; Nootropic Agents; Stroke

2012
Membrane stabilizer: citicoline.
    Current medical research and opinion, 2002, Volume: 18 Suppl 2

    Topics: Animals; Cell Membrane; Cytidine Diphosphate Choline; Europe; Humans; Japan; Nootropic Agents; Randomized Controlled Trials as Topic; Stroke; United States

2002
Oral citicoline in acute ischemic stroke: an individual patient data pooling analysis of clinical trials.
    Stroke, 2002, Volume: 33, Issue:12

    Topics: Acute Disease; Administration, Oral; Aged; Brain Ischemia; Cytidine Diphosphate Choline; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Neuroprotective Agents; Odds Ratio; Prospective Studies; Randomized Controlled Trials as Topic; Recovery of Function; Severity of Illness Index; Stroke; Time Factors; Treatment Outcome

2002
Therapeutic applications of citicoline for stroke and cognitive dysfunction in the elderly: a review of the literature.
    Alternative medicine review : a journal of clinical therapeutic, 2004, Volume: 9, Issue:1

    Topics: Alzheimer Disease; Animals; Brain Injuries; Cognition Disorders; Cytidine Diphosphate Choline; Humans; Models, Animal; Nootropic Agents; Stroke

2004
Cytidine 5'-diphosphocholine (CDP-choline) in stroke and other CNS disorders.
    Neurochemical research, 2005, Volume: 30, Issue:1

    Topics: Animals; Central Nervous System Diseases; Cytidine Diphosphate Choline; Humans; Stroke

2005
Citicoline--the first effective neuroprotectant to be combined with thrombolysis in acute ischemic stroke?
    Journal of the neurological sciences, 2006, Sep-25, Volume: 247, Issue:2

    Topics: Animals; Clinical Trials as Topic; Cytidine Diphosphate Choline; Disease Models, Animal; Drug Therapy, Combination; Humans; Neuroprotective Agents; Stroke; Thrombolytic Therapy

2006
An overview of acute stroke therapy: past, present, and future.
    Archives of internal medicine, 2000, Nov-27, Volume: 160, Issue:21

    Topics: Acute Disease; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antibodies; Brain Ischemia; Calcium Channel Blockers; Cardiovascular Agents; Cell Adhesion Molecules; Clinical Trials as Topic; Cytidine Diphosphate Choline; Cytokines; Drug Therapy, Combination; Fibrinolytic Agents; Free Radical Scavengers; gamma-Aminobutyric Acid; Growth Substances; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; N-Methylaspartate; Neuroprotective Agents; Nootropic Agents; Piperidines; Stroke; Thiazoles; Thrombolytic Therapy

2000

Trials

11 trial(s) available for cytidine diphosphate choline and Apoplexy

ArticleYear
Citicoline in acute ischemic stroke: A randomized controlled trial.
    PloS one, 2022, Volume: 17, Issue:5

    Topics: Brain Ischemia; Cytidine Diphosphate Choline; Double-Blind Method; Humans; Ischemia; Ischemic Stroke; Stroke

2022
Efficacy of Citicoline as a Neuroprotector in children with post cardiac arrest: a randomized controlled clinical trial.
    European journal of pediatrics, 2021, Volume: 180, Issue:4

    Topics: Adult; Brain Injuries; Brain Ischemia; Child; Cytidine Diphosphate Choline; Heart Arrest; Humans; Stroke

2021
Long-term treatment with citicoline may improve poststroke vascular cognitive impairment.
    Cerebrovascular diseases (Basel, Switzerland), 2013, Volume: 35, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Chi-Square Distribution; Cognition; Cognition Disorders; Cytidine Diphosphate Choline; Dementia, Vascular; Disability Evaluation; Drug Administration Schedule; Female; Humans; Logistic Models; Male; Middle Aged; Neuropsychological Tests; Nootropic Agents; Odds Ratio; Predictive Value of Tests; Recovery of Function; Spain; Stroke; Stroke Rehabilitation; Time Factors; Treatment Outcome; Young Adult

2013
Edaravone - citicoline comparative study in acute ischemic stroke (ECCS-AIS).
    The Journal of the Association of Physicians of India, 2012, Volume: 60

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Antipyrine; Brain Ischemia; Cytidine Diphosphate Choline; Edaravone; Female; Follow-Up Studies; Humans; Male; Middle Aged; Neuroprotective Agents; Stroke; Treatment Outcome; Young Adult

2012
Citicoline in the treatment of acute ischaemic stroke: an international, randomized, multicentre, placebo-controlled study (ICTUS trial) is the use of Citicoline is beneficial for acute ischaemic stroke?
    JPMA. The Journal of the Pakistan Medical Association, 2013, Volume: 63, Issue:11

    Topics: Brain Ischemia; Cytidine Diphosphate Choline; Humans; Nootropic Agents; Stroke; Treatment Failure

2013
[The possibilities of increase of efficacy of rehabilitation of stroke patients with neglect syndrome].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2014, Volume: 114, Issue:10

    Topics: Aged; Cytidine Diphosphate Choline; Female; Humans; Male; Middle Aged; Nootropic Agents; Perceptual Disorders; Stroke; Stroke Rehabilitation; Treatment Outcome

2014
Efficacy and safety of oral citicoline in acute ischemic stroke: drug surveillance study in 4,191 cases.
    Methods and findings in experimental and clinical pharmacology, 2009, Volume: 31, Issue:3

    Topics: Administration, Oral; Aged; Brain Ischemia; Cytidine Diphosphate Choline; Drug Evaluation; Female; Humans; Korea; Male; Stroke; Time Factors

2009
[Comparative aspects of using neuroprotectors in the management of patients with ischemic stroke].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2011, Volume: 111, Issue:8 Pt 2

    Topics: Adult; Aged; Amino Acids; Cytidine Diphosphate Choline; Female; Heme; Humans; Male; Middle Aged; Neuroprotective Agents; Stroke; Treatment Outcome

2011
[Influence of neuroprotectors with choline-positive action on the level of brain-injury markers during acute ischemic stroke].
    Eksperimental'naia i klinicheskaia farmakologiia, 2012, Volume: 75, Issue:3

    Topics: Biomarkers; Blood-Brain Barrier; Brain Ischemia; Cytidine Diphosphate Choline; Glycerylphosphorylcholine; Humans; Nootropic Agents; Phosphopyruvate Hydratase; S100 Proteins; Stroke

2012
Effect of citicoline on ischemic lesions as measured by diffusion-weighted magnetic resonance imaging. Citicoline 010 Investigators.
    Annals of neurology, 2000, Volume: 48, Issue:5

    Topics: Aged; Brain; Brain Ischemia; Cytidine Diphosphate Choline; Double-Blind Method; Female; Humans; Magnetic Resonance Imaging; Male; Prognosis; Stroke

2000
A phase III randomized efficacy trial of 2000 mg citicoline in acute ischemic stroke patients.
    Neurology, 2001, Nov-13, Volume: 57, Issue:9

    Topics: Acute Disease; Aged; Brain Ischemia; Cytidine Diphosphate Choline; Female; Humans; Male; Nootropic Agents; Stroke; Treatment Outcome

2001

Other Studies

29 other study(ies) available for cytidine diphosphate choline and Apoplexy

ArticleYear
EFFECT OF INVESTIGATIONAL COMBINATIONS OF NEUROPROTECTANTS ON THE LEVEL OF S 100 AND NSE PROTEIN IN THE BLOOD SERUM OF PATIENTS WITH MODERATE AND SEVERE ISCHEMIC STROKE.
    Georgian medical news, 2023, Issue:342

    Topics: Brain Ischemia; Cytidine Diphosphate Choline; Humans; Ischemic Stroke; Neuroprotective Agents; Phosphopyruvate Hydratase; S100 Proteins; Serum; Stroke

2023
Dendrimer grafted albumin nanoparticles for the treatment of post cerebral stroke damages: A proof of concept study.
    Colloids and surfaces. B, Biointerfaces, 2019, Dec-01, Volume: 184

    Topics: Albumins; Animals; Biological Transport; Blood-Brain Barrier; Cytidine Diphosphate Choline; Dendrimers; Drug Carriers; Drug Delivery Systems; Humans; Mice, Inbred BALB C; Nanoparticles; Nootropic Agents; PC12 Cells; Proof of Concept Study; Rats; Stroke

2019
Citicoline (CDP-choline) increases Sirtuin1 expression concomitant to neuroprotection in experimental stroke.
    Journal of neurochemistry, 2013, Volume: 126, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Blotting, Western; Brain Ischemia; Cells, Cultured; Cytidine Diphosphate Choline; Drug Synergism; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Knockout; Monocytes; Naphthols; Neurons; Neuroprotective Agents; Nootropic Agents; Rats; Rats, Inbred F344; Resveratrol; Sirtuin 1; Stilbenes; Stroke

2013
Long-Term Treatment with Citicoline Prevents Cognitive Decline and Predicts a Better Quality of Life after a First Ischemic Stroke.
    International journal of molecular sciences, 2016, Mar-16, Volume: 17, Issue:3

    Topics: Aged; Brain Ischemia; Cognitive Dysfunction; Cytidine Diphosphate Choline; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Quality of Life; Random Allocation; Stroke

2016
[Assessing the impact of citicoline on the efficiency of rehabilitation measures in patients with ischemic stroke].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2016, Volume: 116, Issue:2

    Topics: Activities of Daily Living; Aged; Cognition; Cytidine Diphosphate Choline; Female; Humans; Male; Middle Aged; Stroke; Stroke Rehabilitation; Treatment Outcome

2016
Label-free CEST MRI Detection of Citicoline-Liposome Drug Delivery in Ischemic Stroke.
    Theranostics, 2016, Volume: 6, Issue:10

    Topics: Animals; Brain; Cytidine Diphosphate Choline; Disease Models, Animal; Drug Carriers; Injections, Intra-Articular; Liposomes; Magnetic Resonance Imaging; Nootropic Agents; Rats; Stroke

2016
Citicoline for acute ischemic stroke in Mexican hospitals: a retrospective postmarketing analysis.
    Methods and findings in experimental and clinical pharmacology, 2010, Volume: 32, Issue:5

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Brain Ischemia; Case-Control Studies; Cytidine Diphosphate Choline; Female; Humans; Male; Middle Aged; Neuroprotective Agents; Product Surveillance, Postmarketing; Retrospective Studies; Stroke

2010
Serial MRI study of the enhanced therapeutic effects of liposome-encapsulated citicoline in cerebral ischemia.
    International journal of pharmaceutics, 2011, Feb-28, Volume: 405, Issue:1-2

    Topics: Animals; Brain; Brain Ischemia; Cerebral Infarction; Cytidine Diphosphate Choline; Disease Models, Animal; Dose-Response Relationship, Drug; Infarction, Middle Cerebral Artery; Injections, Intraperitoneal; Injections, Intravenous; Liposomes; Magnetic Resonance Imaging; Male; Nootropic Agents; Rats; Rats, Sprague-Dawley; Stroke

2011
[Efficacy and safety of the combined therapy with citicholine and actovegin in the acute period of ischemic stroke].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2010, Volume: 110, Issue:9 Pt 2

    Topics: Aged; Combined Modality Therapy; Cytidine Diphosphate Choline; Drug Therapy, Combination; Female; Heme; Humans; Male; Middle Aged; Neuroprotective Agents; Stroke; Treatment Outcome

2010
CDP-choline treatment increases circulating endothelial progenitor cells in acute ischemic stroke.
    Neurological research, 2011, Volume: 33, Issue:6

    Topics: Aged; Aged, 80 and over; Brain Ischemia; Cell Count; Cells, Cultured; Cytidine Diphosphate Choline; Endothelial Cells; Female; Humans; Male; Middle Aged; Prospective Studies; Stem Cells; Stroke; Treatment Outcome

2011
CDP-choline treatment induces brain plasticity markers expression in experimental animal stroke.
    Neurochemistry international, 2012, Volume: 60, Issue:3

    Topics: Animals; Apoptosis; Biomarkers; Blotting, Western; Brain Chemistry; Brain Ischemia; Cell Proliferation; Cytidine Diphosphate Choline; Glial Fibrillary Acidic Protein; Immunohistochemistry; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Magnetic Resonance Imaging; Male; Neuronal Plasticity; Nootropic Agents; Rats; Rats, Sprague-Dawley; Stroke; Synaptophysin; Vascular Endothelial Growth Factor A

2012
[Comparison of efficacy of different neurometabolic and vasoactive medicines in ischemic stroke patients's rehabilitation].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2011, Volume: 111, Issue:10 Pt 1

    Topics: Adult; Aged; Brain Ischemia; Cytidine Diphosphate Choline; Female; Humans; Male; Middle Aged; Neurotransmitter Agents; Stroke; Stroke Rehabilitation

2011
Citicoline enhances neuroregenerative processes after experimental stroke in rats.
    Stroke, 2012, Volume: 43, Issue:7

    Topics: Animals; Cytidine Diphosphate Choline; Disease Models, Animal; Male; Neurogenesis; Neuroprotective Agents; Random Allocation; Rats; Rats, Wistar; Stroke

2012
[Neuroprotective treatment with citicoline (ceraxon) in patients with ischemic stroke].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2012, Volume: 112, Issue:3 Pt 2

    Topics: Administration, Oral; Adult; Aged; Cytidine Diphosphate Choline; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Neuroprotective Agents; Stroke

2012
CDP-choline at high doses is as effective as i.v. thrombolysis in experimental animal stroke.
    Neurological research, 2012, Volume: 34, Issue:7

    Topics: Animals; Cytidine Diphosphate Choline; Disease Models, Animal; Infusions, Intravenous; Male; Nootropic Agents; Random Allocation; Rats; Rats, Long-Evans; Stroke; Thrombolytic Therapy; Tissue Plasminogen Activator; Treatment Outcome

2012
Stroke: Treatment for acute stroke--the end of the citicoline saga.
    Nature reviews. Neurology, 2012, Volume: 8, Issue:9

    Topics: Clinical Trials as Topic; Cytidine Diphosphate Choline; Humans; Nootropic Agents; Stroke

2012
Poststroke pharmacotherapy: another ictus.
    Stroke, 2012, Volume: 43, Issue:12

    Topics: Acute Disease; Cerebral Revascularization; Cytidine Diphosphate Choline; Fibrinolytic Agents; Humans; Nootropic Agents; Randomized Controlled Trials as Topic; Stroke

2012
[The role of neuroprotection in complex rehabilitation of patients with ischemic stroke].
    Likars'ka sprava, 2012, Issue:7

    Topics: Brain Ischemia; Clinical Trials as Topic; Cognition; Cytidine Diphosphate Choline; Drug Therapy, Combination; Humans; Neuroprotective Agents; Nootropic Agents; Stroke; Stroke Rehabilitation

2012
Citicoline in stroke and TBI clinical trials.
    Nature reviews. Neurology, 2013, Volume: 9, Issue:3

    Topics: Clinical Trials as Topic; Cytidine Diphosphate Choline; Humans; Nootropic Agents; Stroke

2013
CDP-choline liposomes provide significant reduction in infarction over free CDP-choline in stroke.
    Brain research, 2005, Oct-05, Volume: 1058, Issue:1-2

    Topics: Animals; Brain; Brain Infarction; Brain Ischemia; Cholesterol; Choline; Cytidine Diphosphate Choline; Disease Models, Animal; Drug Combinations; Drug Synergism; G(M1) Ganglioside; Liposomes; Male; Phagocytosis; Phosphatidylcholines; Rats; Rats, Inbred SHR; Reperfusion Injury; Stroke; Treatment Outcome

2005
Targets of cytoprotection in acute ischemic stroke: present and future.
    Cerebrovascular diseases (Basel, Switzerland), 2006, Volume: 21 Suppl 2

    Topics: Animals; Brain; Brain Ischemia; Cytidine Diphosphate Choline; Cytoprotection; Drug Evaluation, Preclinical; Excitatory Amino Acid Transporter 2; Glutamic Acid; Humans; Ischemic Preconditioning; Meta-Analysis as Topic; Neuropharmacology; Neuroprotective Agents; Polymorphism, Genetic; Promoter Regions, Genetic; Randomized Controlled Trials as Topic; Stroke

2006
Neurorepair versus neuroprotection in stroke.
    Cerebrovascular diseases (Basel, Switzerland), 2006, Volume: 21 Suppl 2

    Topics: Animals; Brain; Cell Differentiation; Cell Movement; Cell Proliferation; Clinical Trials as Topic; Combined Modality Therapy; Cytidine Diphosphate Choline; Dopamine Agents; Humans; Neuronal Plasticity; Neurons; Neuroprotective Agents; Regenerative Medicine; Selective Serotonin Reuptake Inhibitors; Stem Cell Transplantation; Stem Cells; Stroke; Stroke Rehabilitation

2006
Thrombolysis and neuroprotection in cerebral ischemia.
    Cerebrovascular diseases (Basel, Switzerland), 2006, Volume: 21 Suppl 2

    Topics: Animals; Brain; Brain Ischemia; Clinical Trials as Topic; Cytidine Diphosphate Choline; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Neuroprotective Agents; Rats; Recombinant Proteins; Stroke; Thrombolytic Therapy; Time Factors; Tissue Plasminogen Activator

2006
A chronic treatment with CDP-choline improves functional recovery and increases neuronal plasticity after experimental stroke.
    Neurobiology of disease, 2007, Volume: 26, Issue:1

    Topics: Animals; Brain Chemistry; Cytidine Diphosphate Choline; Dendrites; Dendritic Spines; Functional Laterality; Male; Neuronal Plasticity; Nootropic Agents; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Stroke

2007
Citicoline. Monograph.
    Alternative medicine review : a journal of clinical therapeutic, 2008, Volume: 13, Issue:1

    Topics: Amblyopia; Amyloid beta-Peptides; Bipolar Disorder; Brain Injuries; Cell Membrane; Cognition Disorders; Cytidine Diphosphate Choline; Glaucoma; Humans; Intracranial Hemorrhages; Neurotransmitter Agents; Phosphatidylcholines; Spinal Cord Injuries; Stroke

2008
What's new with neuroprotective agents in stroke?
    Drugs in R&D, 1999, Volume: 1, Issue:1

    Topics: Animals; Chlormethiazole; Cytidine Diphosphate Choline; Drugs, Investigational; Humans; Neuroprotective Agents; Nootropic Agents; Piperidines; Stroke; Thiazoles

1999
Cytidine (5') diphosphocholine-induced decrease in cerebral platelet activating factor is due to inactivation of its synthesizing enzyme cholinephosphotransferase in aged rats.
    Neuroscience letters, 2001, Feb-23, Volume: 299, Issue:3

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Aging; Animals; Cell Membrane; Cerebral Cortex; Cytidine Diphosphate Choline; Diacylglycerol Cholinephosphotransferase; Food, Formulated; Isoenzymes; Male; Nootropic Agents; Phospholipases A; Platelet Activating Factor; Rats; Rats, Wistar; Stroke; Subcellular Fractions

2001
News about neuroprotectants for the treatment of stroke.
    JAMA, 2002, Mar-13, Volume: 287, Issue:10

    Topics: Clinical Trials as Topic; Cytidine Diphosphate Choline; Excitatory Amino Acid Antagonists; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Magnesium Sulfate; Neuroprotective Agents; Phosphatidylcholines; Stroke; Time Factors

2002
Α-aryl-N-alkyl nitrones, as potential agents for stroke treatment: synthesis, theoretical calculations, antioxidant, anti-inflammatory, neuroprotective, and brain-blood barrier permeability properties.
    Journal of medicinal chemistry, 2012, Jan-12, Volume: 55, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Blood-Brain Barrier; Cell Hypoxia; Cell Survival; Cells, Cultured; Cerebral Cortex; Edema; Female; Free Radical Scavengers; Hydroxyl Radical; Lipid Peroxidation; Lipoxygenase Inhibitors; Male; Necrosis; Neurons; Neuroprotective Agents; Nitric Oxide Donors; Nitrogen Oxides; Oximes; Permeability; Quinolines; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Stereoisomerism; Stroke; Structure-Activity Relationship; Superoxides

2012