Page last updated: 2024-08-21

cytidine diphosphate choline and Alzheimer Disease

cytidine diphosphate choline has been researched along with Alzheimer Disease in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (30.00)18.2507
2000's6 (20.00)29.6817
2010's6 (20.00)24.3611
2020's9 (30.00)2.80

Authors

AuthorsStudies
Gavrilova, SI; Ponomareva, EV; Roshchina, IF; Selezneva, ND1
Cotroneo, AM; Gareri, P; Veronese, N1
AbouElhassan, KM; Ahmed, YM; Hussein, AK; Safwat, MA; Sarhan, HA; Taye, A1
Antonelli Incalzi, R; Bonvicini, M; Lelli, D; Pedone, C; Travaglini, S1
Azadi, A; Azadi, S; Farjadian, F; Mohammadi Samani, S; Mozafari, N1
Anlacan, VMM; Espiritu, AI; Piamonte, BLC1
Cotroneo, AM; Gareri, P; Orsitto, G; Putignano, S1
Castagna, A; Fabbo, A; Lacava, R; Manzo, C; Ruberto, C; Ruotolo, G2
Fedorova, YB; Gavrilova, SI; Kochkina, EG; Kozlova, DI; Nalivaeva, NN; Zhuravin, IА1
Castagna, A; Cotroneo, AM; Gareri, P; Ruotolo, G1
Castagna, A; Conforti, R; Cotroneo, AM; Gareri, P; Marino, S; Putignano, D; Putignano, S; Santamaria, F1
Alvarez-Sabín, J; Román, GC1
Fedorova, IaB; Gavrilova, SI; Kalyn, IaB; Kolykhalov, IV1
Castagna, A; Cerqua, G; Cervera, P; Cotroneo, AM; Fiorillo, F; Gareri, P; Grella, R; Lacava, R; Maddonni, A; Marino, S; Pluderi, A; Putignano, D; Putignano, S; Rocca, F1
Conant, R; Schauss, AG1
Shen, ZX1
Abate, G; Ambrosoli, L; Azzini, C; Balestreri, R; Bartorelli, L; Bordin, A; Crepaldi, G; Cristianini, G; Cucinotta, D; Parnetti, L1
Caamaño, J; Cacabelos, R; Franco-Maside, A; Gómez, MJ1
Caamaño, J; Cacabelos, R; Franco, A; Gómez, MJ1
Alvarez, XA; Caamaño, J; Cacabelos, R; Fernández-Novoa, L; Franco-Maside, A2
Alvarez, XA; Caamaño, J; Cacabelos, R; Fernández-Novoa, L; Franco-Maside, A; Gómez, MJ1
Alcaraz, M; Alvarez, XA; Cacabelos, R; Corzo, L; Fernández-Novoa, L; Laredo, M; Lozano, R; Mouzo, R; Pérez, P; Pichel, V; Secades, JJ; Zas, R1
Blusztajn, JK; Farber, SA; Slack, BE1
Alvarez, A; Cacabelos, R; Fenández-Novoa, L; Lombardi, VR1
Alexandrov, AV1
Blount, PJ; McDeavitt, JT; Nguyen, CD1
de la Morena, E1
Agut, J; Ortiz, JA1

Reviews

6 review(s) available for cytidine diphosphate choline and Alzheimer Disease

ArticleYear
Is Citicoline Effective in Preventing and Slowing Down Dementia?-A Systematic Review and a Meta-Analysis.
    Nutrients, 2023, Jan-12, Volume: 15, Issue:2

    Topics: Alzheimer Disease; Cognition; Cognition Disorders; Cognitive Dysfunction; Cytidine Diphosphate Choline; Humans

2023
Effects of Citicoline as an Adjunct Treatment for Alzheimer's Disease: A Systematic Review.
    Journal of Alzheimer's disease : JAD, 2020, Volume: 76, Issue:2

    Topics: Alzheimer Disease; Case-Control Studies; Cognition; Cytidine Diphosphate Choline; Drug Therapy, Combination; Humans; Nootropic Agents; Randomized Controlled Trials as Topic; Treatment Outcome

2020
Citicoline in vascular cognitive impairment and vascular dementia after stroke.
    Stroke, 2011, Volume: 42, Issue:1 Suppl

    Topics: Alzheimer Disease; Brain Ischemia; Clinical Trials as Topic; Cognition; Cytidine Diphosphate Choline; Dementia, Vascular; Humans; Neuroprotective Agents; Nootropic Agents; Recovery of Function; Stroke

2011
Therapeutic applications of citicoline for stroke and cognitive dysfunction in the elderly: a review of the literature.
    Alternative medicine review : a journal of clinical therapeutic, 2004, Volume: 9, Issue:1

    Topics: Alzheimer Disease; Animals; Brain Injuries; Cognition Disorders; Cytidine Diphosphate Choline; Humans; Models, Animal; Nootropic Agents; Stroke

2004
Citicoline. Ferrer Internacional.
    Current opinion in investigational drugs (London, England : 2000), 2001, Volume: 2, Issue:12

    Topics: Alzheimer Disease; Animals; Brain Ischemia; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cytidine Diphosphate Choline; Humans; Multiple Sclerosis; Nootropic Agents; Structure-Activity Relationship

2001
Clinical use of cholinomimetic agents: a review.
    The Journal of head trauma rehabilitation, 2002, Volume: 17, Issue:4

    Topics: Administration, Oral; Adult; Aged; Alzheimer Disease; Brain Injuries; Carbamates; Clinical Trials as Topic; Cytidine Diphosphate Choline; Donepezil; Female; Follow-Up Studies; Humans; Indans; Injections, Intravenous; Injury Severity Score; Male; Middle Aged; Parasympathomimetics; Phenylcarbamates; Physostigmine; Piperidines; Rivastigmine; Severity of Illness Index; Tacrine; Treatment Outcome

2002

Trials

6 trial(s) available for cytidine diphosphate choline and Alzheimer Disease

ArticleYear
[Ceraxon (citicoline) in the treatment of the mild cognitive impairment syndrome].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2011, Volume: 111, Issue:12

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognitive Dysfunction; Cytidine Diphosphate Choline; Female; Humans; Male; Middle Aged; Nootropic Agents; Syndrome

2011
Posatirelin for the treatment of late-onset Alzheimer's disease: a double-blind multicentre study vs citicoline and ascorbic acid.
    Acta neurologica Scandinavica, 1995, Volume: 92, Issue:2

    Topics: Aged; Alzheimer Disease; Ascorbic Acid; Brain; Cholinergic Agents; Cytidine Diphosphate Choline; Double-Blind Method; Female; Humans; Male; Neuropsychological Tests; Severity of Illness Index; Thyrotropin-Releasing Hormone

1995
Brain mapping activity and mental performance after chronic treatment with CDP-choline in Alzheimer's disease.
    Methods and findings in experimental and clinical pharmacology, 1994, Volume: 16, Issue:8

    Topics: Aged; Alzheimer Disease; Brain Mapping; Cognition; Cytidine Diphosphate Choline; Electroencephalography; Female; Humans; Male; Mental Processes; Middle Aged; Psychiatric Status Rating Scales

1994
Double-blind placebo-controlled study with citicoline in APOE genotyped Alzheimer's disease patients. Effects on cognitive performance, brain bioelectrical activity and cerebral perfusion.
    Methods and findings in experimental and clinical pharmacology, 1999, Volume: 21, Issue:9

    Topics: Aged; Alzheimer Disease; Apolipoproteins E; Brain; Cognition; Cytidine Diphosphate Choline; Double-Blind Method; Electroencephalography; Female; Genotype; Hemodynamics; Histamine; Humans; Interleukin-1; Male; Middle Aged; Nootropic Agents; Pilot Projects; Placebos; Regional Blood Flow; Time Factors

1999
A pharmacogenomic approach to Alzheimer's disease.
    Acta neurologica Scandinavica. Supplementum, 2000, Volume: 176

    Topics: Adjuvants, Immunologic; Aged; Aged, 80 and over; Alzheimer Disease; Apolipoproteins E; Cognition; Cytidine Diphosphate Choline; Drug Therapy, Combination; Exons; Female; Genotype; Glycosides; Humans; Male; Membrane Proteins; Middle Aged; Nootropic Agents; Piracetam; Presenilin-1; Presenilin-2; Prognosis; Treatment Outcome

2000
Efficacy of CDP-choline in the treatment of senile alterations in memory.
    Annals of the New York Academy of Sciences, 1991, Volume: 640

    Topics: Alzheimer Disease; Cytidine Diphosphate Choline; Dementia; Humans; Memory

1991

Other Studies

18 other study(ies) available for cytidine diphosphate choline and Alzheimer Disease

ArticleYear
[Citicoline in the treatment of cognitive impairment in first-degree relatives of AD patients: the influence of the ApoE genotype].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2021, Volume: 121, Issue:10. Vyp. 2

    Topics: Alzheimer Disease; Apolipoproteins E; Cognitive Dysfunction; Cytidine Diphosphate Choline; Genotype; Humans; Neuropsychological Tests

2021
An Overview of Combination Treatment with Citicoline in Dementia.
    Reviews on recent clinical trials, 2022, Volume: 17, Issue:1

    Topics: Acetylcholinesterase; Aged; Alzheimer Disease; Cholinesterase Inhibitors; Cytidine Diphosphate Choline; Humans; Memantine; Prospective Studies

2022
Brain Targeting of Citicoline Sodium via Hyaluronic Acid-Decorated Novel Nano-Transbilosomes for Mitigation of Alzheimer's Disease in a Rat Model: Formulation, Optimization, in vitro and in vivo Assessment.
    International journal of nanomedicine, 2022, Volume: 17

    Topics: Alzheimer Disease; Animals; Brain; Cytidine Diphosphate Choline; Drug Carriers; Hyaluronic Acid; MicroRNAs; NF-kappa B; Rats; Sodium

2022
Simvastatin-chitosan-citicoline conjugates nanoparticles as the co-delivery system in Alzheimer susceptible patients.
    International journal of biological macromolecules, 2020, Aug-01, Volume: 156

    Topics: Alzheimer Disease; Chitosan; Cytidine Diphosphate Choline; Disease Susceptibility; Drug Carriers; Humans; Nanoparticles; Simvastatin

2020
The Importance of Citicoline in Combined Treatment in Dementia: What did the Citimem Study Teach us?
    Reviews on recent clinical trials, 2021, Volume: 16, Issue:2

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition; Cytidine Diphosphate Choline; Humans; Memantine; Retrospective Studies

2021
A Retrospective Study on the Benefits of Combined Citicoline, Memantine, and Acetylcholinesterase Inhibitor Treatments in Older Patients Affected with Alzheimer's Disease.
    Journal of Alzheimer's disease : JAD, 2021, Volume: 79, Issue:4

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Cholinesterase Inhibitors; Cytidine Diphosphate Choline; Female; Humans; Male; Memantine; Nootropic Agents; Retrospective Studies

2021
The CITIMERIVA Study: CITIcoline plus MEmantina plus RIVAstigmine in Older Patients Affected with Alzheimer's Disease.
    Clinical drug investigation, 2021, Volume: 41, Issue:2

    Topics: Activities of Daily Living; Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Cholinesterase Inhibitors; Cognition; Comorbidity; Cytidine Diphosphate Choline; Female; Humans; Italy; Male; Memantine; Retrospective Studies; Rivastigmine

2021
[The activity of blood serum cholinesterases and neprilysin as potential biomarkers of mild-cognitive impairment and Alzheimer's disease].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2015, Volume: 115, Issue:12

    Topics: Acetylcholinesterase; Aged; Alzheimer Disease; Biomarkers; Butyrylcholinesterase; Cognitive Dysfunction; Cytidine Diphosphate Choline; Disease Progression; Female; Humans; Male; Neprilysin; Nootropic Agents

2015
The CITIRIVAD Study: CITIcoline plus RIVAstigmine in Elderly Patients Affected with Dementia Study.
    Clinical drug investigation, 2016, Volume: 36, Issue:12

    Topics: Activities of Daily Living; Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Cholinesterase Inhibitors; Cognition; Cytidine Diphosphate Choline; Female; Humans; Male; Neuropsychological Tests; Retrospective Studies; Rivastigmine; Transdermal Patch

2016
The Citicholinage Study: Citicoline Plus Cholinesterase Inhibitors in Aged Patients Affected with Alzheimer's Disease Study.
    Journal of Alzheimer's disease : JAD, 2017, Volume: 56, Issue:2

    Topics: Administration, Oral; Affect; Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Cholinesterase Inhibitors; Cognition; Comorbidity; Cytidine Diphosphate Choline; Disease Progression; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Mental Status and Dementia Tests; Nootropic Agents; Retrospective Studies; Treatment Outcome

2017
Retrospective and observational study to assess the efficacy of citicoline in elderly patients suffering from stupor related to complex geriatric syndrome.
    Clinical interventions in aging, 2012, Volume: 7

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Confusion; Cytidine Diphosphate Choline; Female; Humans; Male; Nootropic Agents; Retrospective Studies; Severity of Illness Index; Stupor

2012
Brain cholinesterases: III. Future perspectives of AD research and clinical practice.
    Medical hypotheses, 2004, Volume: 63, Issue:2

    Topics: Acetylcarnitine; Alzheimer Disease; Brain; Cholinesterases; Cytidine Diphosphate Choline; Enzyme Activators; Humans; Meclofenoxate; Selegiline; Vitamin E

2004
Effects of CDP-choline on cognition and cerebral hemodynamics in patients with Alzheimer's disease.
    Methods and findings in experimental and clinical pharmacology, 1994, Volume: 16, Issue:3

    Topics: Aged; Alzheimer Disease; Blood Pressure; Cerebrovascular Circulation; Cognition; Cytidine Diphosphate Choline; Female; Heart Rate; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Ultrasonography, Doppler, Transcranial; Vascular Resistance

1994
CDP-choline-induced blood histamine changes in Alzheimer's disease.
    Methods and findings in experimental and clinical pharmacology, 1994, Volume: 16, Issue:4

    Topics: Administration, Oral; Aged; Alzheimer Disease; Chromatography, High Pressure Liquid; Cytidine Diphosphate Choline; Female; Histamine; Humans; Male; Middle Aged

1994
Effect of CDP-choline on cognition and immune function in Alzheimer's disease and multi-infarct dementia.
    Annals of the New York Academy of Sciences, 1993, Sep-24, Volume: 695

    Topics: Aged; Alzheimer Disease; Amyloid beta-Protein Precursor; Blood Pressure; Cognition; Cytidine Diphosphate Choline; Dementia, Multi-Infarct; Humans; Interleukin-1; Middle Aged; Neuropsychological Tests; Promoter Regions, Genetic

1993
Therapeutic effects of CDP-choline in Alzheimer's disease. Cognition, brain mapping, cerebrovascular hemodynamics, and immune factors.
    Annals of the New York Academy of Sciences, 1996, Jan-17, Volume: 777

    Topics: Aged; Alzheimer Disease; Brain Mapping; Cerebrovascular Circulation; Cognition; Cytidine Diphosphate Choline; Cytokines; Female; Hemodynamics; Histamine; Humans; Male; Middle Aged

1996
Acceleration of phosphatidylcholine synthesis and breakdown by inhibitors of mitochondrial function in neuronal cells: a model of the membrane defect of Alzheimer's disease.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2000, Volume: 14, Issue:14

    Topics: Alzheimer Disease; Animals; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Choline; Cytidine Diphosphate Choline; Dinitrophenols; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glycerylphosphorylcholine; Membranes; Mitochondria; Neurons; PC12 Cells; Phosphatidylcholines; Phosphorylcholine; Rats; Sodium Azide; Time Factors; Uncoupling Agents

2000
Age-related changes in memory and their pharmacologic modulation.
    Annals of the New York Academy of Sciences, 1991, Volume: 640

    Topics: Aging; Alzheimer Disease; Animals; Avoidance Learning; Cytidine Diphosphate Choline; Memory; Mice; Mice, Inbred Strains

1991