Page last updated: 2024-08-21

cytidine diphosphate choline and Aging

cytidine diphosphate choline has been researched along with Aging in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199012 (44.44)18.7374
1990's9 (33.33)18.2507
2000's4 (14.81)29.6817
2010's2 (7.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Das, N; Dungdung, SR; Ghosh, S; Mandal, AK; Sarkar, S1
Ferrari, F; Gorini, A; Villa, RF1
Teather, LA; Wurtman, RJ1
Crespo, D; Fernandez-Viadero, C; Megias, M; Verduga, R3
Arrigoni, E; Benzi, G; Curti, D; Dagani, F; Dossena, M; Marzatico, F; Polgatti, M; Raimondo, S; Villa, RF1
Grau, T; Ortiz, JA; Romero, A; Sacristán, A1
Lozano Fernández, R1
De Medio, GE; Piccinin, GL; Porcellati, G; Trovarelli, G1
Bleasdale, JE; Johnston, JM; MacDonald, PC; Quirk, JG1
Choy, PC1
Brunetti, M; Gaiti, A; Porcellati, G; Sitkievicz, D1
Getova, D; Kehayov, RA; Lazarova, MB; Mosharrof, AH; Petkov, VD; Petkov, VV; Vaglenova, J1
Avola, R; Costa, A; Giuffrida-Stella, AM; Gorini, A; Ingrao, F; Magri, G; Ragusa, N; Reale, S; Villa, RF1
Alvarez, XA; Cacabelos, R; Corzo, D; Daniele, D; Fernández-Novoa, L; Laredo, M; Mouzo, R; Perea, JE1
Aguilar, J; Giménez, R2
Babb, SM; Cohen, BM; Gruber, SA; Renshaw, PF; Villafuerte, RA; Wald, LL; Yurgelun-Todd, DA1
Dranginis, PL; Feldman, DA; Kovac, CR; Weinhold, PA1
Rooney, SA1
Choy, PC; Lim, PH; Vance, DE1
Agut, J; Ortiz, JA1
Aguilar, J; Giménez, R; Raïch, J1
Ceda, GP; Ceresini, G; Denti, L; Hoffman, AR; Magnani, D; Marchini, L; Valenti, G1
Avola, R; Condorelli, DF; Giuffrida Stella, AM; Ragusa, N; Reale, S; Renis, M; Villa, RF1
Mosharrof, AH; Petkov, VD; Petkov, VV1

Reviews

1 review(s) available for cytidine diphosphate choline and Aging

ArticleYear
Development of the pulmonary surfactant system during late fetal and early postnatal life.
    Mead Johnson Symposium on Perinatal and Developmental Medicine, 1978, Issue:14

    Topics: Acyltransferases; Aging; Animals; Animals, Newborn; Choline Kinase; Choline-Phosphate Cytidylyltransferase; Cytidine Diphosphate Choline; Diacylglycerol Cholinephosphotransferase; Female; Fetus; Gestational Age; Humans; Lung; Nucleotidyltransferases; Phosphatidate Phosphatase; Pregnancy; Pulmonary Surfactants; Rabbits; Sphingomyelins

1978

Trials

3 trial(s) available for cytidine diphosphate choline and Aging

ArticleYear
Citicoline improves memory performance in elderly subjects.
    Methods and findings in experimental and clinical pharmacology, 1997, Volume: 19, Issue:3

    Topics: Aged; Aging; Blood Pressure; Cross-Over Studies; Cytidine Diphosphate Choline; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Lymphocyte Count; Male; Memory; Mental Recall; Middle Aged; Nimodipine; Nootropic Agents; Pattern Recognition, Visual

1997
Chronic citicoline increases phosphodiesters in the brains of healthy older subjects: an in vivo phosphorus magnetic resonance spectroscopy study.
    Psychopharmacology, 2002, Volume: 161, Issue:3

    Topics: Administration, Oral; Aged; Aging; Analysis of Variance; Brain; Brain Chemistry; Cytidine Diphosphate Choline; Dose-Response Relationship, Drug; Double-Blind Method; Ethanolamines; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nootropic Agents; Phosphatidylcholines; Phosphorylcholine; Time Factors; Verbal Learning

2002
Effects of cytidine 5'-diphosphocholine administration on basal and growth hormone-releasing hormone-induced growth hormone secretion in elderly subjects.
    Acta endocrinologica, 1991, Volume: 124, Issue:5

    Topics: Aged; Aged, 80 and over; Aging; Cytidine Diphosphate Choline; Female; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Infusions, Intravenous; Male; Middle Aged; Pituitary Gland, Anterior

1991

Other Studies

23 other study(ies) available for cytidine diphosphate choline and Aging

ArticleYear
Mannosylated liposomal cytidine 5' diphosphocholine prevent age related global moderate cerebral ischemia reperfusion induced mitochondrial cytochrome c release in aged rat brain.
    Neuroscience, 2010, Dec-29, Volume: 171, Issue:4

    Topics: Aging; Analysis of Variance; Animals; Brain; Brain Ischemia; Catalase; Cytidine Diphosphate Choline; Cytochromes c; Disease Models, Animal; Glutathione; Lipid Peroxidation; Liposomes; Male; Mannose; Microscopy, Electron, Transmission; Mitochondria; Nootropic Agents; Rats; Rats, Wistar; Reperfusion; Statistics as Topic; Superoxide Dismutase

2010
Effect of CDP-choline on age-dependent modifications of energy- and glutamate-linked enzyme activities in synaptic and non-synaptic mitochondria from rat cerebral cortex.
    Neurochemistry international, 2012, Volume: 61, Issue:8

    Topics: Aging; Animals; Catalysis; Citric Acid Cycle; Cytidine Diphosphate Choline; Enzyme Activation; Enzymes; Frontal Lobe; Glutamic Acid; Male; Mitochondria; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Random Allocation; Rats; Rats, Wistar; Synaptosomes

2012
Dietary cytidine (5')-diphosphocholine supplementation protects against development of memory deficits in aging rats.
    Progress in neuro-psychopharmacology & biological psychiatry, 2003, Volume: 27, Issue:4

    Topics: Administration, Oral; Aging; Animals; Cytidine Diphosphate Choline; Diet; Disease Models, Animal; Female; Hippocampus; Memory Disorders; Nootropic Agents; Rats; Rats, Sprague-Dawley

2003
Chronic treatment with a precursor of cellular phosphatidylcholine ameliorates morphological and behavioral effects of aging in the mouse [correction of rat] hippocampus.
    Annals of the New York Academy of Sciences, 2004, Volume: 1019

    Topics: Aging; Animals; Cytidine Diphosphate Choline; Hippocampus; Male; Memory; Mice; Phosphatidylcholines; Phospholipids

2004
Age-dependent modification of drug interference on the enzymatic activities of the rat brain.
    Experimental gerontology, 1980, Volume: 15, Issue:6

    Topics: Age Factors; Aging; Animals; Brain; Cytidine Diphosphate Choline; Dihydroergotoxine; Male; Nicergoline; Papaverine; Rats; Suloctidil; Theophylline; Trimetazidine; Vinca Alkaloids; Vincamine

1980
Study of subacute toxicity of CDP-choline after 30 days of oral administration to rats.
    Arzneimittel-Forschung, 1983, Volume: 33, Issue:7A

    Topics: Administration, Oral; Aging; Animals; Choline; Cytidine Diphosphate Choline; Diet; Eating; Female; Male; Rats; Rats, Inbred Strains; Sex Factors

1983
Efficacy and safety of oral CDP-choline. Drug surveillance study in 2817 cases.
    Arzneimittel-Forschung, 1983, Volume: 33, Issue:7A

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aging; Cerebrovascular Disorders; Child; Choline; Cytidine Diphosphate Choline; Female; Humans; Male; Middle Aged; Sex Factors; Time Factors

1983
The effect of cytidine-diphosphate choline (CDP-choline) on brain lipid changes during aging.
    Journal of neuroscience research, 1984, Volume: 11, Issue:1

    Topics: Aging; Animals; Brain; Carbon Radioisotopes; Choline; Cytidine Diphosphate Choline; Lipid Metabolism; Male; Rats; Rats, Inbred Strains; Tissue Distribution; Tritium

1984
A role for cytidine monophosphate in the regulation of the glycerophospholipid composition of surfactant in developing lung.
    Biochemical and biophysical research communications, 1980, Aug-14, Volume: 95, Issue:3

    Topics: Aging; Animals; Animals, Newborn; Cytidine Diphosphate Choline; Cytidine Monophosphate; Cytidine Triphosphate; Cytosine Nucleotides; Female; Fetus; Lung; Phospholipids; Pregnancy; Pulmonary Surfactants; Rabbits

1980
Control of phosphatidylcholine biosynthesis in myopathic hamster hearts.
    The Journal of biological chemistry, 1982, Sep-25, Volume: 257, Issue:18

    Topics: Aging; Animals; Cardiomyopathies; Choline; Cricetinae; Cytidine Diphosphate Choline; Cytidine Triphosphate; Heart; Kinetics; Mesocricetus; Myocardium; Phosphatidylcholines; Reference Values

1982
Phospholipid metabolism in neuronal and glial cells during aging.
    Neurochemical research, 1981, Volume: 6, Issue:1

    Topics: Aging; Animals; Brain; Cytidine Diphosphate; Cytidine Diphosphate Choline; Ethanolamines; Humans; Neuroglia; Neurons; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rats

1981
Effects of cytidine diphosphate choline on rats with memory deficits.
    Arzneimittel-Forschung, 1993, Volume: 43, Issue:8

    Topics: Aging; Animals; Avoidance Learning; Clonidine; Cytidine Diphosphate Choline; Electroshock; Fetal Alcohol Spectrum Disorders; Hypoxia, Brain; Male; Meclofenoxate; Memory Disorders; Nitrates; Piracetam; Rats; Rats, Wistar; Scopolamine

1993
Effect of CDP-choline treatment on mitochondrial and synaptosomal protein composition in different brain regions during aging.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 1993, Volume: 11, Issue:1

    Topics: Aging; Animals; Brain Chemistry; Cell Membrane; Cytidine Diphosphate Choline; Electrophoresis, Polyacrylamide Gel; Hypoxia, Brain; Immunoblotting; Male; Mitochondria; Nerve Tissue Proteins; Rats; Rats, Wistar; Synaptosomes

1993
Structural changes induced by cytidine-5'-diphosphate choline (CDP-choline) chronic treatment in neurosecretory neurons of the supraoptic nucleus of aged CFW-mice.
    Mechanisms of ageing and development, 1995, Oct-27, Volume: 84, Issue:3

    Topics: Aging; Animals; Cell Count; Cytidine Diphosphate Choline; Male; Mice; Mice, Inbred Strains; Neurons; Neurosecretory Systems; Supraoptic Nucleus

1995
Effects of chronic administration of cytidine-5'-diphosphate choline (CDP choline) on the aged female mouse Harderian gland.
    Anatomy and embryology, 1997, Volume: 195, Issue:2

    Topics: Aging; Animals; Cytidine Diphosphate Choline; Female; Harderian Gland; Mice; Microscopy, Electron; Nootropic Agents; Porphyrins

1997
Effects of CDP-choline administration on brain striatum platelet-activating factor in aging rats.
    European journal of pharmacology, 1998, Mar-05, Volume: 344, Issue:2-3

    Topics: Aging; Animals; Cytidine Diphosphate Choline; Female; Neostriatum; Nootropic Agents; Platelet Activating Factor; Rats; Rats, Sprague-Dawley

1998
Cytidine (5') diphosphocholine-induced decrease in cerebral platelet activating factor is due to inactivation of its synthesizing enzyme cholinephosphotransferase in aged rats.
    Neuroscience letters, 2001, Feb-23, Volume: 299, Issue:3

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Aging; Animals; Cell Membrane; Cerebral Cortex; Cytidine Diphosphate Choline; Diacylglycerol Cholinephosphotransferase; Food, Formulated; Isoenzymes; Male; Nootropic Agents; Phospholipases A; Platelet Activating Factor; Rats; Rats, Wistar; Stroke; Subcellular Fractions

2001
The role of phosphatidylglycerol in the activation of CTP:phosphocholine cytidylyltransferase from rat lung.
    The Journal of biological chemistry, 1978, Jul-25, Volume: 253, Issue:14

    Topics: Aging; Animals; Cytidine Diphosphate Choline; Diphosphates; Enzyme Activation; Female; Fetus; Kinetics; Lung; Magnesium; Molecular Weight; Nucleotidyltransferases; Phosphatidylglycerols; Pregnancy; Rats

1978
Purification and characterization of CTP: cholinephosphate cytidylytransferase from rat liver cytosol.
    The Journal of biological chemistry, 1977, Nov-10, Volume: 252, Issue:21

    Topics: Aging; Animals; Cytidine Diphosphate Choline; Cytidine Triphosphate; Cytosol; Kinetics; Liver; Nucleotidyltransferases; Rats

1977
Age-related changes in memory and their pharmacologic modulation.
    Annals of the New York Academy of Sciences, 1991, Volume: 640

    Topics: Aging; Alzheimer Disease; Animals; Avoidance Learning; Cytidine Diphosphate Choline; Memory; Mice; Mice, Inbred Strains

1991
Changes in brain striatum dopamine and acetylcholine receptors induced by chronic CDP-choline treatment of aging mice.
    British journal of pharmacology, 1991, Volume: 104, Issue:3

    Topics: Aging; Animals; Corpus Striatum; Cytidine Diphosphate Choline; Female; In Vitro Techniques; Membrane Fluidity; Mice; Quinuclidinyl Benzilate; Receptors, Cholinergic; Receptors, Dopamine; Receptors, Dopamine D2; Spectrometry, Fluorescence; Spiperone

1991
Age-dependent changes of nucleic acid labeling in different rat brain regions.
    Neurochemical research, 1989, Volume: 14, Issue:7

    Topics: Aging; Animals; Brain; Cell Nucleus; Cerebellum; Cerebral Cortex; Corpus Striatum; Cytidine Diphosphate Choline; DNA; Electrophoresis, Polyacrylamide Gel; Microsomes; Poly A; Rats; Rats, Inbred Strains; RNA; RNA, Messenger; RNA, Neoplasm; RNA, Ribosomal

1989
Effects of meclofenoxate and citicholine on learning and memory in aged rats.
    Acta physiologica et pharmacologica Bulgarica, 1987, Volume: 13, Issue:4

    Topics: Aging; Animals; Choline; Cytidine Diphosphate Choline; Glycolates; Learning; Male; Meclofenoxate; Memory; Rats; Rats, Inbred Strains; Scopolamine

1987