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cytidine diphosphate choline and Acute Brain Injuries

cytidine diphosphate choline has been researched along with Acute Brain Injuries in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19907 (22.58)18.7374
1990's5 (16.13)18.2507
2000's7 (22.58)29.6817
2010's9 (29.03)24.3611
2020's3 (9.68)2.80

Authors

AuthorsStudies
Barber, J; Chen, J; Chesnut, R; Cruz Navarro, J; DeSantis, SM; Diaz-Arrastia, R; Ferguson, AR; Foreman, B; Heckler, B; Manley, GT; Markowitz, AJ; Robertson, C; Temkin, N; Vassar, M; Wright, DW; Yamal, JM; Yaseen, A1
Abdel-Aziz, N; Moustafa, EM; Saada, HN1
El Amrousy, D; Faheem, A; Mehrez, M; Salamah, A1
Arenth, P; Bagiella, E; Benn, EK; Dikmen, S; Hart, T; Hesdorffer, DC; Novack, TA; Ricker, JH; Zafonte, R1
Grieb, P1
Borlongan, CV; Coll-Andreu, M; Costa-Miserachs, D; Jacotte-Simancas, A; Portell-Cortés, I; Torras-Garcia, M1
Berga, S; Kochanek, PM; Kumar, RG; Santarsieri, M; Wagner, AK1
Asghari, A; Asghari, M; Haghjoo, AG; Pezeshki, A; Sattarnezhad, A; Sattarnezhad, N; Shokouhi, G1
Agrawal, N; Poole, NA1
Ansel, B; Diaz-Arrastia, R; Eisenberg, H; Friedewald, WT; Jallo, J; Lee, SM; Levin, B; Merchant, R; Novack, T; Ricker, J; Temkin, N; Timmons, SD; Zafonte, R1
Bian, XX; Qi, CP; Yuan, XS1
Secades, JJ1
Ansel, BM; Bagiella, E; Diaz-Arrastia, R; Dikmen, SS; Eisenberg, H; Friedewald, WT; Hart, T; Hesdorffer, DC; Jallo, J; Melton, S; Merchant, RE; Novack, TA; Ricker, JH; Temkin, NR; Timmons, SD; Zafonte, RD1
Riechers, RG; Ruff, RL1
Dempsey, RJ; Raghavendra Rao, VL1
TANAKAMARU, S1
Conant, R; Schauss, AG1
Jomin, M; Lesoin, F; Lozes, G; Verier, A1
Cohadon, F; Poletto, B; Richer, E1
Kontos, HA; Lamb, RG; Wei, EP1
Dixon, CE; Ma, X; Marion, DW1
Hochanadel, G; Spiers, PA1
Başkaya, MK; Dempsey, RJ; Doğan, A; Rao, AM1
Blount, PJ; McDeavitt, JT; Nguyen, CD1
Ogashiwa, M; Takeuchi, K1
Abe, H; Kawaguchi, Y; Masu, K; Takahashi, M; Tanji, H1
Hara, M; Ogashiwa, M; Okada, J; Takeuchi, K; Tanaka, Y1
Aso Escario, J; Calatayud Maldonado, V; Calatayud Pérez, JB1
Cotticelli, MG; De Rosa, M; Galletti, P; Morana, A; Vaccaro, R; Zappia, V1
Lozano, R1

Reviews

6 review(s) available for cytidine diphosphate choline and Acute Brain Injuries

ArticleYear
Neuroprotective properties of citicoline: facts, doubts and unresolved issues.
    CNS drugs, 2014, Volume: 28, Issue:3

    Topics: Animals; Brain; Brain Injuries; Brain Ischemia; Clinical Trials as Topic; Cytidine Diphosphate Choline; Humans; Neurodegenerative Diseases; Neuroprotective Agents; Stroke

2014
Cholinomimetic agents and neurocognitive impairment following head injury: a systematic review.
    Brain injury, 2008, Volume: 22, Issue:7-8

    Topics: Brain Injuries; Cholinesterase Inhibitors; Cognition Disorders; Cytidine Diphosphate Choline; Humans; Lecithins; Neuropsychological Tests; Nootropic Agents; Physostigmine; Surface-Active Agents; Time Factors

2008
Citicoline: pharmacological and clinical review, 2010 update.
    Revista de neurologia, 2011, Mar-14, Volume: 52 Suppl 2

    Topics: Brain Injuries; Brain Ischemia; Cerebrovascular Disorders; Clinical Trials as Topic; Cognition Disorders; Cytidine Diphosphate Choline; Humans; Learning; Memory; Stroke; Synaptic Transmission

2011
Therapeutic applications of citicoline for stroke and cognitive dysfunction in the elderly: a review of the literature.
    Alternative medicine review : a journal of clinical therapeutic, 2004, Volume: 9, Issue:1

    Topics: Alzheimer Disease; Animals; Brain Injuries; Cognition Disorders; Cytidine Diphosphate Choline; Humans; Models, Animal; Nootropic Agents; Stroke

2004
Clinical use of cholinomimetic agents: a review.
    The Journal of head trauma rehabilitation, 2002, Volume: 17, Issue:4

    Topics: Administration, Oral; Adult; Aged; Alzheimer Disease; Brain Injuries; Carbamates; Clinical Trials as Topic; Cytidine Diphosphate Choline; Donepezil; Female; Follow-Up Studies; Humans; Indans; Injections, Intravenous; Injury Severity Score; Male; Middle Aged; Parasympathomimetics; Phenylcarbamates; Physostigmine; Piperidines; Rivastigmine; Severity of Illness Index; Tacrine; Treatment Outcome

2002
CDP-choline in the treatment of cranio-encephalic traumata.
    Journal of the neurological sciences, 1991, Volume: 103 Suppl

    Topics: Brain Injuries; Coma; Cytidine Diphosphate Choline; Electroencephalography; Humans

1991

Trials

9 trial(s) available for cytidine diphosphate choline and Acute Brain Injuries

ArticleYear
Integrating, Harmonizing, and Curating Studies With High-Frequency and Hourly Physiological Data: Proof of Concept from Seven Traumatic Brain Injury Data Sets.
    Journal of neurotrauma, 2023, Volume: 40, Issue:21-22

    Topics: Brain Injuries; Brain Injuries, Traumatic; Cytidine Diphosphate Choline; Humans; Information Dissemination; Prospective Studies

2023
Efficacy of Citicoline as a Neuroprotector in children with post cardiac arrest: a randomized controlled clinical trial.
    European journal of pediatrics, 2021, Volume: 180, Issue:4

    Topics: Adult; Brain Injuries; Brain Ischemia; Child; Cytidine Diphosphate Choline; Heart Arrest; Humans; Stroke

2021
Early trajectory of psychiatric symptoms after traumatic brain injury: relationship to patient and injury characteristics.
    Journal of neurotrauma, 2014, Apr-01, Volume: 31, Issue:7

    Topics: Adult; Brain Injuries; Cytidine Diphosphate Choline; Double-Blind Method; Female; Humans; Male; Mental Disorders; Middle Aged; Neuropsychological Tests; Nootropic Agents; Risk Factors

2014
Variable neuroendocrine-immune dysfunction in individuals with unfavorable outcome after severe traumatic brain injury.
    Brain, behavior, and immunity, 2015, Volume: 45

    Topics: Adolescent; Adult; Aged; Brain Injuries; Case-Control Studies; Cohort Studies; Cytidine Diphosphate Choline; Double-Blind Method; Fas Ligand Protein; Female; Glasgow Outcome Scale; Humans; Hydrocortisone; Hypothermia, Induced; Inflammation; Intercellular Adhesion Molecule-1; Interleukin-10; Interleukin-1beta; Interleukin-6; Male; Middle Aged; Nootropic Agents; Prognosis; Prospective Studies; Trauma Severity Indices; Treatment Outcome; Tumor Necrosis Factor-alpha; Young Adult

2015
Effects of citicoline on level of consciousness, serum level of fetuin-A and matrix Gla-protein (MGP) in trauma patients with diffuse axonal injury (DAI) and GCS≤8.
    Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2014, Volume: 20, Issue:6

    Topics: Adolescent; Adult; Aged; alpha-2-HS-Glycoprotein; Brain Injuries; Calcium-Binding Proteins; Consciousness; Cytidine Diphosphate Choline; Diffuse Axonal Injury; Double-Blind Method; Extracellular Matrix Proteins; Female; Glasgow Coma Scale; Humans; Male; Matrix Gla Protein; Middle Aged; Nootropic Agents; Treatment Outcome; Young Adult

2014
The citicoline brain injury treatment (COBRIT) trial: design and methods.
    Journal of neurotrauma, 2009, Volume: 26, Issue:12

    Topics: Adolescent; Adult; Aged; Brain; Brain Injuries; Clinical Protocols; Cytidine Diphosphate Choline; Disability Evaluation; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Neuroprotective Agents; Neuropsychological Tests; Nootropic Agents; Outcome Assessment, Health Care; Placebos; Research Design; Severity of Illness Index; Young Adult

2009
Effect of citicoline on functional and cognitive status among patients with traumatic brain injury: Citicoline Brain Injury Treatment Trial (COBRIT).
    JAMA, 2012, Nov-21, Volume: 308, Issue:19

    Topics: Adolescent; Adult; Brain Injuries; Cognition Disorders; Cytidine Diphosphate Choline; Double-Blind Method; Female; Glasgow Coma Scale; Humans; Male; Middle Aged; Nootropic Agents; Severity of Illness Index; Trauma Centers; Treatment Outcome; Young Adult

2012
[A precursor of phospholipids in the treatment of severe traumatic comas].
    Neuro-Chirurgie, 1982, Volume: 28, Issue:4

    Topics: Adult; Aged; Brain Injuries; Choline; Clinical Trials as Topic; Coma; Cytidine Diphosphate Choline; Double-Blind Method; Female; Humans; Male; Middle Aged; Random Allocation; Time Factors

1982
Effects of CDP-choline on the recovery of patients with head injury.
    Journal of the neurological sciences, 1991, Volume: 103 Suppl

    Topics: Adolescent; Adult; Brain Injuries; Chi-Square Distribution; Child; Child, Preschool; Cytidine Diphosphate Choline; Female; Glasgow Coma Scale; Humans; Infant; Male; Middle Aged; Prognosis; Single-Blind Method

1991

Other Studies

16 other study(ies) available for cytidine diphosphate choline and Acute Brain Injuries

ArticleYear
The impact of citicoline on brain injury in rats subjected to head irradiation.
    Environmental science and pollution research international, 2021, Volume: 28, Issue:8

    Topics: Animals; Apoptosis; Brain Injuries; Cytidine Diphosphate Choline; Oxidative Stress; Phosphatidylinositol 3-Kinases; Rats

2021
Effects of voluntary physical exercise, citicoline, and combined treatment on object recognition memory, neurogenesis, and neuroprotection after traumatic brain injury in rats.
    Journal of neurotrauma, 2015, May-15, Volume: 32, Issue:10

    Topics: Animals; Behavior, Animal; Brain Injuries; Combined Modality Therapy; Cytidine Diphosphate Choline; Disease Models, Animal; Male; Memory, Long-Term; Memory, Short-Term; Motor Activity; Neurogenesis; Neuroprotection; Nootropic Agents; Rats; Rats, Sprague-Dawley; Recognition, Psychology

2015
Effect of recombinant human erythropoietin on serum S100B protein and interleukin-6 levels after traumatic brain injury in the rat.
    Neurologia medico-chirurgica, 2010, Volume: 50, Issue:5

    Topics: Animals; Brain Injuries; Cytidine Diphosphate Choline; Dose-Response Relationship, Drug; Erythropoietin; Humans; Inflammation; Interleukin-6; Male; Nerve Growth Factors; Neuroprotective Agents; Random Allocation; Rats; Rats, Sprague-Dawley; Recombinant Proteins; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Time Factors

2010
Effective treatment of traumatic brain injury: learning from experience.
    JAMA, 2012, Nov-21, Volume: 308, Issue:19

    Topics: Brain Injuries; Cognition Disorders; Cytidine Diphosphate Choline; Female; Humans; Male; Nootropic Agents

2012
Cytidinediphosphocholine treatment to decrease traumatic brain injury-induced hippocampal neuronal death, cortical contusion volume, and neurological dysfunction in rats.
    Journal of neurosurgery, 2003, Volume: 98, Issue:4

    Topics: Animals; Brain Injuries; Cell Death; Cytidine Diphosphate Choline; Disease Models, Animal; Hippocampus; Male; Neurons; Nootropic Agents; Phospholipases; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate

2003
[EXPERIMENTAL AND CLINICAL STUDIES ON CDP-CHOLINE THERAPY FOR BRAIN INJURIES].
    Kumamoto Igakkai zasshi. The Journal of the Kumamoto Medical Society, 1964, Mar-25, Volume: 38

    Topics: Animals; Biomedical Research; Brain Injuries; Choline; Cytidine Diphosphate Choline; Lagomorpha; Nucleotides; Rabbits; Research

1964
Citicoline. Monograph.
    Alternative medicine review : a journal of clinical therapeutic, 2008, Volume: 13, Issue:1

    Topics: Amblyopia; Amyloid beta-Peptides; Bipolar Disorder; Brain Injuries; Cell Membrane; Cognition Disorders; Cytidine Diphosphate Choline; Glaucoma; Humans; Intracranial Hemorrhages; Neurotransmitter Agents; Phosphatidylcholines; Spinal Cord Injuries; Stroke

2008
[Post-traumatic cerebral edema. Physiopathology and treatment].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1984, Mar-01, Volume: 60, Issue:10

    Topics: Alfaxalone Alfadolone Mixture; Barbiturates; Brain Edema; Brain Injuries; Cytidine Diphosphate Choline; Diazepam; Hormones; Humans; Osmolar Concentration; Prognosis; Respiration, Artificial; Sodium Oxybate; Water-Electrolyte Imbalance

1984
Increased phospholipase C activity after experimental brain injury.
    Journal of neurosurgery, 1982, Volume: 56, Issue:5

    Topics: Animals; Blood Pressure; Brain; Brain Injuries; Cats; Cerebrovascular Circulation; Cytidine Diphosphate Choline; Diglycerides; Phosphatidic Acids; Phospholipases; Type C Phospholipases

1982
Effects of CDP-choline treatment on neurobehavioral deficits after TBI and on hippocampal and neocortical acetylcholine release.
    Journal of neurotrauma, 1997, Volume: 14, Issue:3

    Topics: Acetylcholine; Animals; Brain Injuries; Cerebral Cortex; Cytidine Diphosphate Choline; Hippocampus; Male; Rats; Rats, Sprague-Dawley

1997
Citicoline for traumatic brain injury: report of two cases, including my own.
    Journal of the International Neuropsychological Society : JINS, 1999, Volume: 5, Issue:3

    Topics: Acute Disease; Adult; Brain Injuries; Cytidine Diphosphate Choline; Female; Humans; Injury Severity Score; Male; Nootropic Agents

1999
Neuroprotective effects of citicoline on brain edema and blood-brain barrier breakdown after traumatic brain injury.
    Journal of neurosurgery, 2000, Volume: 92, Issue:3

    Topics: Animals; Blood-Brain Barrier; Brain Edema; Brain Injuries; Cerebral Cortex; Cytidine Diphosphate Choline; Extracellular Space; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley

2000
Intrathecal pharmacotherapy in coma.
    Acta neurochirurgica, 1976, Volume: 34, Issue:1-4

    Topics: Adult; Aged; Brain Injuries; Choline; Coma; Cytidine Diphosphate Choline; Electroencephalography; Female; Humans; Injections, Spinal; Male; Meningoencephalitis; Middle Aged; Subarachnoid Hemorrhage; Time Factors

1976
Intrathecal administration of CDP-choline into the lower lumbar subarachnoid space in two patients with post-traumatic akinetic mutism.
    Fukushima journal of medical science, 1976, Volume: 22, Issue:1-2

    Topics: Aged; Akinetic Mutism; Brain Injuries; Choline; Cytidine Diphosphate Choline; Humans; Injections, Spinal; Male; Middle Aged; Subarachnoid Space

1976
Studies on the intrathecal pharmacotherapy. Part I: CDP-choline.
    International journal of clinical pharmacology and biopharmacy, 1975, Volume: 12, Issue:3

    Topics: Adolescent; Adult; Aged; Animals; Autoradiography; Brain; Brain Death; Brain Injuries; Choline; Consciousness; Cytidine Diphosphate Choline; Electroencephalography; Female; Humans; Injections, Spinal; Male; Middle Aged; Rats; Spinal Cord

1975
Biochemical rationale for the use of CDPcholine in traumatic brain injury: pharmacokinetics of the orally administered drug.
    Journal of the neurological sciences, 1991, Volume: 103 Suppl

    Topics: Administration, Oral; Animals; Brain Injuries; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Cytidine Diphosphate Choline; Dogs; Female; Liver; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Inbred Strains; Tritium

1991