cytidine has been researched along with Neoplasms in 63 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (20.63) | 18.7374 |
| 1990's | 3 (4.76) | 18.2507 |
| 2000's | 21 (33.33) | 29.6817 |
| 2010's | 21 (33.33) | 24.3611 |
| 2020's | 5 (7.94) | 2.80 |
| Authors | Studies |
|---|---|
| Arellano, ML; Boggon, TJ; Brat, DJ; Chen, GZ; Chen, J; Chen, PR; DeBerardinis, RJ; Elf, S; Fan, J; Gu, TL; He, C; Hitosugi, T; Hurwitz, SJ; Ji, Q; Jiang, L; Kang, HB; Kang, S; Khoury, HJ; Khuri, FR; Lee, BH; Lei, Q; Li, Y; Lin, R; Lonial, S; Mao, H; Mitsche, M; Seo, JH; Shan, C; Sudderth, J; Tucker, M; Wang, D; Wu, S; Xie, J; Ye, K; Zhang, L; Zhang, S; Zhou, L | 1 |
| Chen, J; Chen, X; Fang, H; Guo, Z; Hu, Y; Li, Y; Lin, L; Tian, H | 1 |
| Chen, CL; DeWeerd, RA; Green, AM; Hyrien, O; Németh, E; Petryk, N; Póti, Á; Szüts, D | 1 |
| Pyeon, D; Santiago, ML; Warren, CJ | 1 |
| Ahmad, A; Alkhatabi, HA; Choudhry, H; Dalhat, MH; Khan, MI; Mohammed, MRS; Rehan, M | 1 |
| Chelico, L; Vizeacoumar, FJ; Vizeacoumar, FS; Wong, L | 1 |
| Fukushima, M; Hiramoto, A; Kim, HS; Matsuda, A; Naito, T; Sato, A; Takano, T; Wataya, Y | 1 |
| Breckpot, K; De Smedt, SC; Descamps, B; Dewitte, H; Lentacker, I; Van Bockstal, M; Vanhove, C; Verbeke, R; Wayteck, L | 1 |
| Dammann, RH; Jiménez, AP; Küster, M; Richter, AM; Witharana, C; Woods, M | 1 |
| Chen, Z; Dai, Q; Li, J; Lu, Z; Luo, G; Qi, M; Shen, B; Wang, H; Wu, Y; Zheng, Z | 1 |
| Arlt, VM; Kliem, C; Krais, AM; Schmeiser, HH | 1 |
| Balboni, B; Benaim, E; El Hassouni, B; Giovannetti, E; Heaton, C; Honeywell, RJ; Kim, DJ; Lee, YB; Peters, GJ; Peterson, C; Poore, J; Sarkisjan, D | 1 |
| Arakawa, K; Falchook, GS; Fu, S; Hong, DS; Kurzrock, R; Naing, A; Wheler, JJ; Zinner, RG | 1 |
| Balkin, ER; Bryan, JN; Jia, F; Kumar, SR; Lewis, MR | 1 |
| Ahn, CH; Fine, T; Kashi, R; Kaye, J; Kim, DJ; Lee, YB; Ohne, O; Peters, GJ; Smid, K; Yang, MY | 1 |
| Terui, Y | 1 |
| Bonney, PL; Dhawan, D; Fourez, LM; Fulkerson, CM; Jones, DR; Jones, PA; Klaunig, JE; Knapp, DW; Marquez, VE; Wang, Z; Wu, Q | 1 |
| Berridge, G; Goldin, R; Kessler, BM; Kriaucionis, S; Pugh, KM; Thézénas, ML; Zauri, M | 1 |
| Sivanand, S; Wellen, KE | 1 |
| Blanco, S; Frye, M; Popis, MC | 1 |
| Butter, R; Linnekamp, JF; Medema, JP; Spijker, R; van Laarhoven, HWM | 1 |
| Wang, M; Yu, N | 1 |
| Issa, JP | 1 |
| Fujioka, A; Fukushima, M; Kazuno, H; Matsuda, A; Sasaki, T; Wataya, Y | 1 |
| Fu, L; Wang, XX | 1 |
| Farkas, DL; Gertych, A; Tajbakhsh, J | 1 |
| Abbruzzese, JL; de Bono, J; Hammond-Thelin, LA; Hoff, P; Iwasaki, M; Lassere, Y; Matsushita, H; Meyers, CA; Mita, A; Norris, J; Rowinsky, EK; Thomas, MB | 1 |
| Fukushima, M; Goda, K; Hiramoto, A; Kim, HS; Kitade, Y; Matsuda, A; Naito, T; Omi, T; Sasaki, T; Sato, A; Wataya, Y | 1 |
| Eitaki, M; Fukushima, M; Inanami, O; Matsuda, A; Meike, S; Morimatsu, M; Yamamori, T; Yamasaki, Y; Yasui, H | 1 |
| Abbruzzese, JL; Friday, B; Lassere, Y; Meyers, CA; Mita, A; Thomas, MB | 1 |
| Kawaguchi, Y; Kitamura, R; Matsuoka, K; Matsushima, E | 1 |
| EIDINOFF, ML; PEREZ, AG; RICH, MA | 1 |
| HURLBERT, RB; KAMMEN, HO | 1 |
| BOND, VP; FEINENDEGEN, LE | 1 |
| Boothman, DA; Bruening, AJ; Hwang, A; Meyers, M; Sedwick, WD; Veigl, ML; Wagner, MW | 1 |
| Hampton, T | 1 |
| Cascalho, M | 1 |
| Cheng, JC; Chuang, J; Greer, S; Jones, PA; Liang, G; Marquez, VE; Orntoft, TF; Thykjaer, T; Weisenberger, DJ; Wozniak, C; Yoo, CB | 1 |
| Bradbury, J | 1 |
| Cheng, JC; Jones, PA; Yoo, CB | 1 |
| Gowher, H; Jeltsch, A | 1 |
| Graves, LM; Huang, M; Mitchell, BS; Wang, Y | 1 |
| Leen, R; Van Gennip, AH; Van Kuilenburg, AB; Verschuur, AC | 1 |
| Ballmer-Hofer, K; Langer-Machova, Z; Marty, C; Schott, H; Schwendener, RA; Sigrist, S | 1 |
| Agbaria, R; Barchi, JJ; Ben-Kasus, T; Cheng, JC; Jones, PA; Kelley, JA; Marquez, VE; Rao, KV; Yoo, CB | 1 |
| Hrdlicka, PJ; Jepsen, JS; Wengel, J | 1 |
| Agbaria, R; Ben-Kasus, T; Cheng, JC; Jones, PA; Kelley, JA; Marquez, VE; Yoo, CB | 1 |
| Alazzouzi, H; Perucho, M; Schwartz, S | 1 |
| Liu, H; Salford, LG; Sjögren, HO; Widegren, B; Xue, ZT | 1 |
| Strong, LC | 1 |
| Cubitt, S; Enns, L; Hirani-Hojatti, S; Karimian, K; Mirzayans, R; Murthy, K; Paterson, MC; Radatus, B | 1 |
| Allegra, CJ; Bastian, A; Chen, AP; Dahut, W; Ford, H; Hamilton, JM; Kelley, JA; Politi, PM; Setser, A; Xie, F | 1 |
| Anant, S; Chester, A; Navaratnam, N; Scott, J | 1 |
| Smrt, J; Veselý, J | 1 |
| Lehmann-Brockhaus, E; Nietmann, H; Schick, P; Trepel, F | 1 |
| Begemann, H; Benedek, S; Eder, M; Fliedner, TM; Kaboth, W; Matzner, M; Schick, P; Theml, H; Trepel, F | 1 |
| Allegra, CJ; Chabner, BA; Chu, E; Grem, JL; Johnson, P; Yeh, GC | 1 |
| Bellet, RE; Custer, RP; Engstrom, PF; Mastrangelo, MJ | 1 |
| Gelboin, HV | 1 |
| Beltz, RE; Hinshaw, DB; Jolley, WB; Waters, RN | 1 |
| Tattersall, MH | 1 |
| Hoshi, A; Kanai, T; Kanzawa, F; Kuretani, K; Yoshida, M | 1 |
| Stiller, KJ | 1 |
21 review(s) available for cytidine and Neoplasms
| Article | Year |
|---|---|
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; Oxidative Stress; Pentose Phosphate Pathway; Phosphogluconate Dehydrogenase; Protein Serine-Threonine Kinases; Ribulosephosphates; Signal Transduction | 2015 |
APOBEC3: Friend or Foe in Human Papillomavirus Infection and Oncogenesis?
Topics: APOBEC Deaminases; Apolipoproteins; Carcinogenesis; Cytidine; Humans; Neoplasms; Papillomavirus Infections; Peptides; Proteins; RNA, Messenger | 2022 |
Impact of Natural Compounds on DNA Methylation Levels of the Tumor Suppressor Gene RASSF1A in Cancer.
Topics: Animals; Biological Products; Cytidine; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Neoplasms; Polyphenols; Tumor Suppressor Proteins; Vitamins | 2017 |
RX-3117 (fluorocyclopentenyl cytosine): a novel specific antimetabolite for selective cancer treatment.
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Biological Availability; Cytidine; Deoxycytidine; Gemcitabine; Humans; Neoplasms; Patient Selection | 2019 |
Posttranscriptional methylation of transfer and ribosomal RNA in stress response pathways, cell differentiation, and cancer.
Topics: Cell Differentiation; Cytidine; Cytosine; Humans; Methylation; Methyltransferases; Neoplasms; RNA Processing, Post-Transcriptional; RNA, Ribosomal; Stress, Physiological | 2016 |
Clinical and biological effects of demethylating agents on solid tumours - A systematic review.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Cytidine; Decitabine; DNA Methylation; Humans; Hydralazine; Immune System; Methylation; Neoplasms; Procaine; Treatment Outcome | 2017 |
Anticancer drug discovery targeting DNA hypermethylation.
Topics: 4-Aminobenzoic Acid; Adenosine; Animals; Antineoplastic Agents; Cytidine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Drug Design; Enzyme Inhibitors; Humans; Hydrazines; Neoplasms; Oligonucleotides, Antisense; para-Aminobenzoates | 2008 |
[Recent advances in DNA demethylation in tumor therapy].
Topics: Animals; Cytidine; DNA Methylation; DNA Modification Methylases; Gene Knockout Techniques; Histone Acetyltransferases; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Neoplasms; RNA Interference; Valproic Acid | 2009 |
A role for DNA mismatch repair in sensing and responding to fluoropyrimidine damage.
Topics: Animals; Base Pair Mismatch; Cytidine; DNA Damage; DNA Repair; Humans; Neoplasms; Pyrimidines; RNA Processing, Post-Transcriptional | 2003 |
Advantages and disadvantages of cytidine deamination.
Topics: Animals; APOBEC-1 Deaminase; APOBEC-3G Deaminase; Base Sequence; Cytidine; Cytidine Deaminase; Cytosine Deaminase; Genes, Immunoglobulin; Humans; Molecular Sequence Data; Neoplasms; Nucleoside Deaminases; Protein Transport; Proteins; Repressor Proteins; Retroviridae Infections | 2004 |
Zebularine: a new drug for epigenetic therapy.
Topics: Azacitidine; Cytidine; DNA Methylation; Epigenesis, Genetic; Genetic Therapy; Humans; Neoplasms; Pyrimidine Nucleosides | 2004 |
Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy.
Topics: Animals; Cytidine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Humans; Neoplasms | 2004 |
Regulation of equilibrative nucleoside uptake by protein kinase inhibitors.
Topics: Animals; Biological Transport; Cytidine; Enzyme Inhibitors; Equilibrative Nucleoside Transport Proteins; Equilibrative Nucleoside Transporter 1; Equilibrative-Nucleoside Transporter 2; ErbB Receptors; Humans; K562 Cells; Models, Biological; Neoplasms; Nucleosides; p38 Mitogen-Activated Protein Kinases; Protein Kinase C; Protein Kinase Inhibitors; Rats | 2004 |
Zebularine: a unique molecule for an epigenetically based strategy in cancer chemotherapy. The magic of its chemistry and biology.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Cytidine; Cytidine Deaminase; DNA; Epigenesis, Genetic; Humans; Models, Chemical; Neoplasms | 2005 |
Zebularine: a unique molecule for an epigenetically based strategy in cancer chemotherapy.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Cytidine; Cytidine Deaminase; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Epigenesis, Genetic; Humans; Kinetics; Models, Chemical; Neoplasms | 2005 |
The nature of cancer and the mechanisms of its control: a review.
Topics: Animals; Cytidine; DNA; Female; Humans; Liver; Mammary Tumor Virus, Mouse; Maternal Age; Mice; Mutation; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Nucleic Acid Conformation; Transplantation, Homologous | 1980 |
RNA editing: cytidine to uridine conversion in apolipoprotein B mRNA.
Topics: Animals; APOBEC-1 Deaminase; Apolipoproteins B; Base Sequence; Catalytic Domain; Cytidine; Cytidine Deaminase; Genetic Therapy; Humans; Models, Molecular; Molecular Sequence Data; Neoplasms; Phylogeny; RNA Editing; RNA, Messenger; Sequence Alignment; Uridine | 2000 |
Antimetabolites.
Topics: Animals; Antimetabolites; Antineoplastic Agents; Cytarabine; Cytidine; Drug Interactions; Drug Resistance; Floxuridine; Fluorouracil; Folic Acid Antagonists; Humans; Methotrexate; Neoplasms | 1991 |
Studies on the mechanism of microsomal hydroxylase induction and its role in carcinogen action.
Topics: Animals; Anthracenes; Benz(a)Anthracenes; Carbon Isotopes; Carcinogens; Cells, Cultured; Cricetinae; Cytidine; Dactinomycin; Electrophoresis; Enzyme Induction; Methylcholanthrene; Mice; Microsomes, Liver; Mixed Function Oxygenases; Neoplasms; Phenobarbital; Protein Biosynthesis; Rats; RNA; RNA Nucleotidyltransferases; Tritium; Uridine | 1972 |
Growth inhibitors rapidly inactivated by the host as potential antineoplastic agents in intra-arterial infusion chemotherapy.
Topics: Animals; Antimetabolites; Antineoplastic Agents; Bradykinin; Capillary Permeability; Cells, Cultured; Cytidine; Humans; Injections, Intra-Arterial; Mitosis; Neoplasms; Rats; RNA; Thymidine; Thymidine Kinase; Tritium; Uridine | 1972 |
The emergence of drug resistance in tumours: a characteristic which may be exploited therapeutically.
Topics: Aminohydrolases; Animals; Cytarabine; Cytidine; DNA; Drug Resistance; Humans; Leukemia; Leukemia L1210; Methotrexate; Neoplasms | 1973 |
4 trial(s) available for cytidine and Neoplasms
| Article | Year |
|---|---|
Phase I dose-escalating study of TAS-106 in combination with carboplatin in patients with solid tumors.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cytidine; Demography; Dose-Response Relationship, Drug; Female; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Nervous System; Young Adult | 2014 |
Phase I and pharmacokinetic study of 3'-C-ethynylcytidine (TAS-106), an inhibitor of RNA polymerase I, II and III,in patients with advanced solid malignancies.
Topics: Adult; Aged; Antineoplastic Agents; Area Under Curve; Biotransformation; Cytidine; Drug Administration Schedule; Enzyme Inhibitors; Feasibility Studies; Female; Half-Life; Humans; Infusions, Intravenous; Kaplan-Meier Estimate; Male; Maximum Tolerated Dose; Metabolic Clearance Rate; Middle Aged; Neoplasms; RNA Polymerase I; RNA Polymerase II; RNA Polymerase III; Texas; Treatment Outcome | 2012 |
A phase I study to determine the safety and pharmacokinetics of intravenous administration of TAS-106 once per week for three consecutive weeks every 28 days in patients with solid tumors.
Topics: Adult; Aged; Antineoplastic Agents; Cytidine; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Neoplasms | 2012 |
Phase I clinical trial of continuous infusion cyclopentenyl cytosine.
Topics: Adult; Aged; Antineoplastic Agents; Bone Marrow; Carbon-Nitrogen Ligases; Chromatography, High Pressure Liquid; Cytidine; Female; Humans; Hypotension; Infusions, Intravenous; Ligases; Male; Metabolic Clearance Rate; Middle Aged; Neoplasms | 1995 |
38 other study(ies) available for cytidine and Neoplasms
| Article | Year |
|---|---|
Combination of epigenetic regulation with gene therapy-mediated immune checkpoint blockade induces anti-tumour effects and immune response in vivo.
Topics: Animals; B7-H1 Antigen; Cell Line, Tumor; Combined Modality Therapy; Cytidine; DNA Methylation; Epigenesis, Genetic; Genetic Therapy; Humans; Immune Checkpoint Inhibitors; Immunity; Immunotherapy; Methyltransferases; Neoplasm Metastasis; Neoplasms; T-Lymphocytes; Tumor Escape; Tumor Microenvironment | 2021 |
Prospectively defined patterns of APOBEC3A mutagenesis are prevalent in human cancers.
Topics: Cytidine; Cytidine Deaminase; Genome, Human; Humans; Mutagenesis; Neoplasms; Proteins | 2022 |
NAT10: An RNA cytidine transferase regulates fatty acid metabolism in cancer cells.
Topics: Acetyltransferases; Cholesterol; Cytidine; Epithelial-Mesenchymal Transition; Fatty Acids; Neoplasms; Palmitates; RNA; Transferases; Triglycerides | 2022 |
APOBEC1 cytosine deaminase activity on single-stranded DNA is suppressed by replication protein A.
Topics: APOBEC-1 Deaminase; Binding, Competitive; Cell Line; Cell Line, Tumor; Cytidine; Deamination; DNA Damage; DNA Replication; DNA, Neoplasm; DNA, Single-Stranded; Facilitated Diffusion; Histones; Humans; Lung; Neoplasm Proteins; Neoplasms; Organ Specificity; Recombinant Fusion Proteins; Replication Protein A; RNA, Messenger; RNA, Neoplasm | 2021 |
Role of the uridine/cytidine kinase 2 mutation in cellular sensitiveness toward 3'-ethynylcytidine treatment of human cancer cells.
Topics: Cell Line, Tumor; Cytidine; Fibrosarcoma; Humans; Neoplasms; Point Mutation; RNA Precursors; RNA Splicing; RNA, Messenger; Uridine Kinase | 2017 |
Co-delivery of nucleoside-modified mRNA and TLR agonists for cancer immunotherapy: Restoring the immunogenicity of immunosilent mRNA.
Topics: Animals; Cancer Vaccines; Cytidine; Dendritic Cells; Female; Immunotherapy; Lipid A; Lipids; Mice, Inbred C57BL; Neoplasms; RNA, Messenger; Toll-Like Receptors | 2017 |
Transfer RNA demethylase ALKBH3 promotes cancer progression via induction of tRNA-derived small RNAs.
Topics: Adenosine; AlkB Homolog 3, Alpha-Ketoglutarate-Dependent Dioxygenase; Animals; Apoptosis; Cell Movement; Cell Proliferation; Cytidine; Disease Progression; HeLa Cells; Humans; Mice; Neoplasm Invasiveness; Neoplasms; Ribonuclease, Pancreatic; RNA, Transfer; Xenograft Model Antitumor Assays | 2019 |
Determination of genomic N3-methylthymidine in human cancer cells treated with nitrosamines using capillary electrophoresis with laser-induced fluorescence.
Topics: A549 Cells; Cytidine; Electrophoresis, Capillary; Fluorescence; Humans; Neoplasms; Nitrosamines; Thymidine | 2019 |
Zebularine significantly sensitises MEC1 cells to external irradiation and radiopharmaceutical therapy when administered sequentially in vitro.
Topics: Apoptosis; Cell Line, Tumor; Chemoradiotherapy; Cytidine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Humans; Neoplasms; Octreotide; Organometallic Compounds | 2014 |
A novel cytidine analog, RX-3117, shows potent efficacy in xenograft models, even in tumors that are resistant to gemcitabine.
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Cytidine; Deoxycytidine; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Gemcitabine; HCT116 Cells; HT29 Cells; Humans; Mice; Mice, Nude; Neoplasms; Xenograft Model Antitumor Assays | 2014 |
[Cytidine].
Topics: Antineoplastic Agents; Arabinonucleosides; Cytarabine; Cytidine; Deoxycytidine; Gemcitabine; Humans; Neoplasms | 2015 |
Pharmacokinetics and toxicity of the novel oral demethylating agent zebularine in laboratory and tumor bearing dogs.
Topics: Administration, Oral; Aldehyde Oxidase; Animals; Chromatography, High Pressure Liquid; Cytidine; Cytosol; DNA Methylation; Dog Diseases; Dogs; Female; Half-Life; Indiana; Liver; Macrolides; Male; Neoplasms; Neutropenia; Schools, Veterinary | 2017 |
CDA directs metabolism of epigenetic nucleosides revealing a therapeutic window in cancer.
Topics: 5-Methylcytosine; Animals; Cell Death; Cell Line, Tumor; Cytidine; Cytidine Deaminase; Cytosine; Deoxycytidine; DNA; DNA Damage; DNA-Directed DNA Polymerase; Epigenesis, Genetic; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Mice; Neoplasms; Nucleotides; Oxidation-Reduction; Phosphotransferases; Substrate Specificity; Up-Regulation; Uridine | 2015 |
Molecular biology: Salvaging the genome.
Topics: Animals; Cytidine; Cytidine Deaminase; Cytosine; Epigenesis, Genetic; Humans; Neoplasms | 2015 |
Cancer prevention: epigenetics steps up to the plate.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Cell Transformation, Neoplastic; Chemoprevention; Cytidine; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Inhibitors; Epigenesis, Genetic; Humans; Models, Biological; Neoplasms | 2008 |
1-(3-C-Ethynyl-beta-D-ribo-pentofuranosyl)cytosine (ECyd, TAS-106), a novel potent inhibitor of RNA polymerase, potentiates the cytotoxicity of CDDP in human cancer cells both in vitro and in vivo.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cisplatin; Cytidine; DNA-Directed RNA Polymerases; Drug Synergism; Enzyme Inhibitors; Humans; Male; Neoplasms; Rats; Rats, Nude; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2009 |
Measuring topology of low-intensity DNA methylation sites for high-throughput assessment of epigenetic drug-induced effects in cancer cells.
Topics: Antineoplastic Agents; Azacitidine; Cell Line, Tumor; Cell Nucleus; Cytidine; Cytosine; DNA Methylation; DNA, Neoplasm; Epigenesis, Genetic; Fluorescence; High-Throughput Screening Assays; Humans; Indoles; Neoplasms; Nucleic Acid Conformation | 2010 |
Association of RNase L with a Ras GTPase-activating-like protein IQGAP1 in mediating the apoptosis of a human cancer cell-line.
Topics: Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Survival; Cytidine; Endoribonucleases; Humans; Immunoprecipitation; In Situ Nick-End Labeling; JNK Mitogen-Activated Protein Kinases; Neoplasms; Phosphorylation; Protein Binding; Protein Interaction Mapping; ras GTPase-Activating Proteins; RNA Interference | 2010 |
A nucleoside anticancer drug, 1-(3-C-ethynyl-β-D-ribo-pentofuranosyl)cytosine (TAS106), sensitizes cells to radiation by suppressing BRCA2 expression.
Topics: Animals; Antineoplastic Agents; BRCA2 Protein; Cells, Cultured; Cricetinae; Cricetulus; Cytidine; Down-Regulation; Drug Evaluation, Preclinical; Gene Expression Regulation, Neoplastic; Homologous Recombination; Humans; Models, Biological; Neoplasms; Nucleosides; Radiation Tolerance; Radiation-Sensitizing Agents | 2011 |
Determination of 3'-C-ethynylcytidine in human plasma and urine by liquid chromatographic-electrospray ionization tandem mass spectrometry.
Topics: Antineoplastic Agents; Calibration; Chromatography, Liquid; Cytidine; Humans; Indicators and Reagents; Neoplasms; Quality Control; Reference Standards; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization | 2003 |
Growth inhibition of a human tumor cell strain by 5-fluorocytidine and 5-fluoro-2'-deoxycytidine: reversal studies.
Topics: Animals; Cytidine; Deoxycytidine; Humans; Neoplasms; Neoplasms, Experimental; Nucleosides; Nucleotides | 1959 |
The formation of cytidine nucleotides and RNA cytosine from orotic acid by the Novikoff tumor in vitro.
Topics: Cytidine; Cytosine; In Vitro Techniques; Neoplasms; Nucleosides; Nucleotides; Orotic Acid; Pyrimidines; RNA | 1959 |
Observations on nuclear RNA during mitosis in human cancer cells in culture (HeLa-S3), studied with tritiated cytidine.
Topics: Cell Division; Cell Nucleus; Cytidine; Mitosis; Neoplasms; Neoplasms, Experimental; Nucleosides; RNA; RNA, Nuclear; Tissue Culture Techniques | 1963 |
Scientists probe shutting down cancer cells by awakening silenced genes.
Topics: Animals; Antineoplastic Agents; Cytidine; DNA Methylation; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Humans; Neoplasms; Pyrimidine Nucleosides | 2004 |
Preferential response of cancer cells to zebularine.
Topics: Antineoplastic Agents; Cell Division; Cell Line, Tumor; Cytidine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA, Neoplasm; Fibroblasts; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, p16; Humans; Neoplasms; Pyrimidine Nucleosides | 2004 |
Zebularine: a candidate for epigenetic cancer therapy.
Topics: Antineoplastic Agents; Cytidine; Epigenesis, Genetic; Humans; Neoplasms; Pyrimidine Nucleosides | 2004 |
Increased cytotoxicity of 2',2'-difluoro-2'-deoxycytidine in human leukemic cell-lines after a preincubation with cyclopentenyl cytosine.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Carbon-Nitrogen Ligases; Cell Line, Tumor; Cell Separation; Clinical Trials as Topic; Cytidine; Deoxycytidine; DNA; Dose-Response Relationship, Drug; Flow Cytometry; Gemcitabine; HL-60 Cells; Humans; Necrosis; Neoplasms; Time Factors | 2004 |
Isolation and characterization of a scFv antibody specific for tumor endothelial marker 1 (TEM1), a new reagent for targeted tumor therapy.
Topics: Antibody Specificity; Antigens, CD; Antigens, Neoplasm; Cell Line; Cytarabine; Cytidine; Humans; Immunoglobulin Fragments; Liposomes; Membrane Proteins; Neoplasm Proteins; Neoplasms; Peptide Library; Recombinant Proteins | 2006 |
Synthesis and biological evaluation of conformationally restricted and nucleobase-modified analogs of the anticancer compound 3'-C-ethynylcytidine (ECyd).
Topics: Antimetabolites; Antineoplastic Agents; Cell Line, Tumor; Chemistry, Pharmaceutical; Cytidine; Drug Design; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Models, Chemical; Neoplasms; Nucleic Acid Conformation; Uracil; Uridine | 2005 |
Mutational dynamics in human tumors confirm the neutral intrinsic instability of the mitochondrial D-loop poly-cytidine repeat.
Topics: Base Sequence; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Colonic Neoplasms; Cytidine; DNA, Mitochondrial; Female; Humans; Microsatellite Repeats; Molecular Sequence Data; Mutation; Neoplasms; Repetitive Sequences, Nucleic Acid | 2006 |
Low dose Zebularine treatment enhances immunogenicity of tumor cells.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cytidine; Cytokines; DNA Methylation; Dose-Response Relationship, Drug; Immunosuppressive Agents; Male; Neoplasms; Rats; Reverse Transcriptase Polymerase Chain Reaction; Spleen; Transfection | 2007 |
Comparative genotoxicity of 2,3'-O-cyclocytidine, beta-xylocytidine and 1-beta-D-arabinofuranosylcytosine in human tumor cell lines.
Topics: Ancitabine; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cell Survival; Child; Cytarabine; Cytidine; DNA Damage; DNA Repair; DNA Replication; DNA, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Leukemia; Neoplasms; Tumor Cells, Cultured | 1994 |
Enzymes relevant to cancer chemotherapy II. Heterogeneity of rat kidney uridine kinase following chromatography on Sepharose 6B coupled to N4-(5-amino-Pentyl)-cytidine.
Topics: Animals; Chromatography, Affinity; Cytidine; Female; Kidney; Neoplasms; Phosphotransferases; Rats; Uridine Kinase | 1977 |
Autotransufsion of 3H-cytidine-labelled blood lymphocytes in patients with Hodgkin's disease and non-Hodgkin patients. I. Limitations of the method.
Topics: Blood Transfusion, Autologous; Cytidine; Hodgkin Disease; Humans; Lymphocytes; Neoplasms; Scleroderma, Systemic; Time Factors | 1975 |
Autotransfusion of 3H-cytidine-labelled blood lymphocytes in patients with Hodgkin's disease and non-Hodgkin patients. II. Exchangeable lymphocyte pools.
Topics: Adult; Aged; Blood Transfusion, Autologous; Cytidine; Female; Hodgkin Disease; Humans; Lymphocytes; Male; Middle Aged; Neoplasms; Scleroderma, Systemic; Time Factors | 1975 |
Hepatotoxicity of 5-azacytidine (NSC-102816) (a clinical and pathologic study).
Topics: Acute Disease; Adult; Aged; Azacitidine; Chemical and Drug Induced Liver Injury; Cytidine; Female; Humans; Kupffer Cells; Liver; Male; Middle Aged; Neoplasms; Triazines | 1973 |
Specific inhibition of DNA synthesis by cyclocytidine.
Topics: Animals; Antineoplastic Agents; Carbon Isotopes; Cells, Cultured; Cyclization; Cytidine; Depression, Chemical; DNA; Leucine; Leukemia L1210; Mice; Neoplasms; Thymidine; Uridine | 1972 |
Problems of in-vitro incubation with radioactive precursors.
Topics: Animals; Antineoplastic Agents; Cytidine; Humans; Neoplasms; Phenylalanine; Proline; Rats; Thymidine; Tritium | 1973 |