cytidine has been researched along with Disease Models, Animal in 34 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (5.88) | 18.7374 |
1990's | 1 (2.94) | 18.2507 |
2000's | 5 (14.71) | 29.6817 |
2010's | 16 (47.06) | 24.3611 |
2020's | 10 (29.41) | 2.80 |
Authors | Studies |
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Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
Abdelnabi, R; Augustijns, P; Breuer, J; Chatterjee, AK; Coelmont, L; Dallmeier, K; De Jonghe, S; Do, TND; Foo, CS; Heylen, E; Jochmans, D; Kaptein, SJF; Langendries, L; Leyssen, P; Mols, R; Neyts, J; Pang, J; Vangeel, L; Vergote, V; Weynand, B; Williams, R; Zhang, X | 1 |
Anthony, DC; Augusto-Oliveira, M; Bayuangga, H; Claridge, TDW; Kuhle, J; Leppert, D; Palace, J; Probert, F; Sealey, M; Tanner, R; Yeo, T | 1 |
Hampton, T | 1 |
Hart, M; Natchus, MG; Painter, GR; Plemper, RK; Toots, M; Yoon, JJ | 1 |
Agostini, ML; Baric, RS; Bluemling, GR; Brown, AJ; Chappell, JD; Denison, MR; Dinnon, KH; George, AS; Graham, RL; Harcourt, J; Hill, CS; Hughes, TM; Kolykhalov, AA; Leist, SR; Lu, X; Montgomery, SA; Natchus, MG; Painter, G; Pruijssers, AJ; Saindane, M; Schäfer, A; Sheahan, TP; Sims, AC; Stevens, LJ; Swanstrom, R; Tamin, A; Thornburg, NJ; Zhou, S | 1 |
Chen, X; Geng, H; Han, H; Hu, Y; Huo, Y; Li, D; Li, H; Liu, M; Ma, X; Wang, J; Wang, L; Yang, L; Yin, S; Yu, W; Zhang, X; Zheng, R | 1 |
Barbian, K; Bosio, CM; Feldmann, F; Feldmann, H; Haddock, E; Hansen, F; Hawman, DW; Jarvis, MA; Leventhal, S; Martens, C; Meade-White, K; Okumura, A; Ricotta, E; Rosenke, K; Rosenke, R; Saturday, G; Schwarz, B | 1 |
Alexander, LEC; Behroozikhah, M; Beutler, N; Burton, DR; Castillo, V; Claire, A; Crotty, S; Dan, JM; Das, S; Duran, J; Fuller, M; Ghosh, P; Katkar, GD; Khandelwal, S; Pretorius, V; Ramirez, SI; Rawlings, SA; Rogers, TF; Sahoo, D; Smith, DM; Taheri, S; Tindle, C | 1 |
Abdelnabi, R; De Jonghe, S; Foo, CS; Maes, P; Neyts, J; Weynand, B | 1 |
Chen, B; Deng, S; Han, X; Hu, Y; Wang, Z; Yu, P; Zhao, Q | 1 |
Chen, M; Chen, S; Deng, J; Lai, L; Li, Z; Liu, Z; Song, Y | 1 |
Lin, S; Lu, X; Qin, W | 1 |
Billiet, A; De Clercq, K; De Vleeschauwer, AR; Goris, N; Kollanur, D; Lefebvre, DJ; Murao, L; Neyts, J | 1 |
Debing, Y; Jochmans, D; Nascimento, MS; Neyts, J; Rocha-Pereira, J; Verbeken, E | 1 |
Chen, SY; Cui, XB; Tang, R; Wang, JN | 1 |
Campbell, RR; Dang, D; Ono, K; Schmidt, BL; Viet, CT; Ye, Y | 1 |
Jochmans, D; Neyts, J; Rocha-Pereira, J | 1 |
Ahn, CH; Fine, T; Kashi, R; Kaye, J; Kim, DJ; Lee, YB; Ohne, O; Peters, GJ; Smid, K; Yang, MY | 1 |
Chen, WC; Kaushik-Basu, N; Lee, JC; Lin, CK; Tseng, CK; Wu, HN; Wu, YH | 1 |
Dock, H; Theodorsson, A; Theodorsson, E | 1 |
Neyts, J; Rocha-Pereira, J; Van Dycke, J | 1 |
Barten-Van Rijbroek, AD; Kal, HB; Leen, R; Rodermond, HM; Van Bree, C; Van Kuilenburg, AB | 1 |
Aslan, E; Bekar, A; Kocaeli, H; Tolunay, S; Ulus, IH | 1 |
Brown, KD; Chen, M; Dyer, LM; Hochwald, SN; Hollingshead, M; Hunter, KW; Kaye, FJ; Marquez, VE; Nawab, A; Shabashvili, D; Steeg, P; Yang, SX; Zajac-Kaye, M | 1 |
Bekar, A; Caner, B; Cansev, M; Kafa, MI; Karli, N; Kurt, MA; Ulus, IH | 1 |
Ansarah-Sobrinho, C; Casellas, R; Dubois, W; Hager, GL; Hakim, O; Klein, I; Kovalchuk, AL; Morse, HC; Nussenzweig, MC; Potter, M; Resch, W; Takizawa, M; Tolarová, H; Yamane, A | 1 |
Alleman, WG; Aprelikova, ON; Chandramouli, GV; Linehan, WM; Mendoza, A; Rodgers, C; Rogers, C; Sopko, NA; Tabios, RL; Torres-Cabala, C; Vasselli, JR | 1 |
Bennink, R; de Bruin, K; Guchelaar, HJ; Leen, R; Pfaffendorf, M; Sand, K; Schimmel, K; Steinmetz, N; van den Hoff, M; van Kuilenburg, A; Vanderheyden, JL; Verschuur, A | 1 |
Cansev, M; Hamurtekin, E; Ilcol, YO; Ulus, IH; Yilmaz, MS | 1 |
Alam, R; Choudhury, BK; Klinman, DM; Sur, N; Sur, S; Wild, JS | 1 |
Gaubert, G; Gosselin, G; Maury, G; Salvatori, D; Vincenzetti, S; Vita, A | 1 |
Ehrlich, MG | 1 |
Bagshaw, MA; Brown, JM; Goffinet, DR; Kaplan, HS | 1 |
34 other study(ies) available for cytidine and Disease Models, Animal
Article | Year |
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Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
The combined treatment of Molnupiravir and Favipiravir results in a potentiation of antiviral efficacy in a SARS-CoV-2 hamster infection model.
Topics: Amides; Animals; Antiviral Agents; COVID-19; COVID-19 Drug Treatment; Cytidine; Disease Models, Animal; Drug Therapy, Combination; Female; Hydroxylamines; Lung; Mesocricetus; Pyrazines; RNA, Viral; Treatment Outcome; Viral Load | 2021 |
Metabolomics detects clinically silent neuroinflammatory lesions earlier than neurofilament-light chain in a focal multiple sclerosis animal model.
Topics: Allantoin; Animals; Biomarkers; Cytidine; Disease Models, Animal; Glucose; Glutamine; Humans; Intermediate Filaments; Multiple Sclerosis; Neurofilament Proteins; Rats | 2022 |
New Flu Antiviral Candidate May Thwart Drug Resistance.
Topics: Animals; Antiviral Agents; Cytidine; Disease Models, Animal; Drug Resistance, Viral; Humans; Hydroxylamines; Influenza, Human; Macaca; Ribonucleosides | 2020 |
Quantitative efficacy paradigms of the influenza clinical drug candidate EIDD-2801 in the ferret model.
Topics: Animals; Antiviral Agents; Cytidine; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Drug Resistance, Viral; Ferrets; HEK293 Cells; Humans; Hydroxylamines; Influenza A virus; Influenza, Human; Madin Darby Canine Kidney Cells; Mutation; Ribonucleosides | 2020 |
An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice.
Topics: Adenosine Monophosphate; Alanine; Animals; Antibiotic Prophylaxis; Antiviral Agents; Betacoronavirus; Cell Line; Coronavirus Infections; COVID-19; Cytidine; Disease Models, Animal; Drug Resistance, Viral; Humans; Hydroxylamines; Lung; Mice; Mice, Inbred C57BL; Middle East Respiratory Syndrome Coronavirus; Models, Molecular; Mutation; Pandemics; Pneumonia, Viral; Primary Cell Culture; Random Allocation; Respiratory System; Ribonucleosides; RNA-Dependent RNA Polymerase; RNA, Viral; SARS-CoV-2; Virus Replication | 2020 |
Amelioration of an Inherited Metabolic Liver Disease through Creation of a De Novo Start Codon by Cytidine Base Editing.
Topics: Animals; Codon, Initiator; Cytidine; Dependovirus; Disease Models, Animal; Feasibility Studies; Gene Editing; Genetic Therapy; Genetic Vectors; HEK293 Cells; Humans; Hydrolases; Inteins; Mice; Tyrosinemias | 2020 |
Orally delivered MK-4482 inhibits SARS-CoV-2 replication in the Syrian hamster model.
Topics: Administration, Oral; Animals; Antiviral Agents; Chlorocebus aethiops; COVID-19; COVID-19 Drug Treatment; Cytidine; Disease Models, Animal; Humans; Hydroxylamines; Mesocricetus; SARS-CoV-2; Vero Cells; Virus Replication | 2021 |
AI-guided discovery of the invariant host response to viral pandemics.
Topics: Angiotensin-Converting Enzyme 2; Animals; Antibodies, Neutralizing; Antiviral Agents; Artificial Intelligence; Autopsy; COVID-19; COVID-19 Drug Treatment; Cricetinae; Cytidine; Databases, Genetic; Disease Models, Animal; Gene Expression Profiling; Gene Regulatory Networks; Genetic Markers; Humans; Hydroxylamines; Interleukin-15; Lung; Mesocricetus; Pandemics; Receptors, Interleukin-15; Virus Diseases | 2021 |
Molnupiravir Inhibits Replication of the Emerging SARS-CoV-2 Variants of Concern in a Hamster Infection Model.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Neutralizing; Antibodies, Viral; Antiviral Agents; COVID-19; COVID-19 Drug Treatment; Cricetinae; Cytidine; Disease Models, Animal; Female; Hydroxylamines; Mutation; Pandemics; SARS-CoV-2; Virus Replication | 2021 |
Cytidine-phosphate-guanosine oligodeoxynucleotides in combination with CD40 ligand decrease periodontal inflammation and alveolar bone loss in a TLR9-independent manner.
Topics: Adjuvants, Immunologic; Alveolar Bone Loss; Animals; B-Lymphocytes; CD40 Ligand; Cells, Cultured; Cytidine; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Gingiva; Guanine Nucleotides; Interleukin-10; Mice, Inbred C57BL; Oligodeoxyribonucleotides; Periodontitis; Real-Time Polymerase Chain Reaction; Reference Values; Reproducibility of Results; Time Factors; Toll-Like Receptor 9 | 2018 |
Highly efficient RNA-guided base editing in rabbit.
Topics: Adenine; Adenosine Deaminase; Animals; Base Pairing; Base Sequence; Blastocyst; Codon, Nonsense; CRISPR-Associated Protein 9; CRISPR-Cas Systems; Cytidine; Cytidine Deaminase; Disease Models, Animal; Founder Effect; Gene Editing; Humans; INDEL Mutation; Mutation, Missense; Rabbits; RNA, Guide, Kinetoplastida; Sequence Alignment | 2018 |
Programmable base editing in zebrafish using a modified CRISPR-Cas9 system.
Topics: Abnormalities, Multiple; Animals; Base Sequence; CRISPR-Cas Systems; Cytidine; Cytidine Deaminase; Disease Models, Animal; Embryo, Nonmammalian; Eye Abnormalities; Female; Gene Editing; Humans; Macrostomia; Male; Mutagenesis, Site-Directed; Point Mutation; RNA, Guide, Kinetoplastida; Thymine; Twist-Related Protein 2; Zebrafish; Zebrafish Proteins | 2018 |
Proof of concept for the inhibition of foot-and-mouth disease virus replication by the anti-viral drug 2'-C-methylcytidine in severe combined immunodeficient mice.
Topics: Animals; Antiviral Agents; Cytidine; Disease Models, Animal; Foot-and-Mouth Disease; Foot-and-Mouth Disease Virus; Mice; Mice, SCID; RNA, Viral | 2014 |
The viral polymerase inhibitor 2'-C-methylcytidine inhibits Norwalk virus replication and protects against norovirus-induced diarrhea and mortality in a mouse model.
Topics: Animal Structures; Animals; Antiviral Agents; Body Weight; Caliciviridae Infections; Cytidine; Diarrhea; Disease Models, Animal; Feces; Female; Male; Mice; Norovirus; Norwalk virus; RNA, Viral; Survival Analysis; Viral Load; Virus Replication | 2013 |
CTP synthase 1, a smooth muscle-sensitive therapeutic target for effective vascular repair.
Topics: Angioplasty, Balloon; Animals; Carbon-Nitrogen Ligases; Carotid Artery Injuries; Cell Cycle; Cell Proliferation; Cells, Cultured; Cytidine; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Inhibitors; Genetic Therapy; Male; Mice; Mice, Inbred C57BL; Molecular Targeted Therapy; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neointima; NM23 Nucleoside Diphosphate Kinases; Rats; Rats, Sprague-Dawley; RNA Interference; Time Factors; Vascular System Injuries | 2013 |
Demethylating drugs as novel analgesics for cancer pain.
Topics: Analgesics, Opioid; Animals; Antineoplastic Agents; Azacitidine; Carcinoma, Squamous Cell; Cytidine; Decitabine; Disease Models, Animal; DNA Methylation; Heterografts; Humans; Immunohistochemistry; In Situ Hybridization; Mice; Mouth Neoplasms; Neurons; Pain; Receptors, Opioid, mu; Reverse Transcriptase Polymerase Chain Reaction; Transduction, Genetic; Trigeminal Ganglion | 2014 |
Prophylactic treatment with the nucleoside analogue 2'-C-methylcytidine completely prevents transmission of norovirus.
Topics: Animals; Antiviral Agents; Caliciviridae Infections; Chemoprevention; Cytidine; Diarrhea; Disease Models, Animal; Female; Male; Mice; Norovirus; Survival Analysis | 2015 |
A novel cytidine analog, RX-3117, shows potent efficacy in xenograft models, even in tumors that are resistant to gemcitabine.
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Cytidine; Deoxycytidine; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Gemcitabine; HCT116 Cells; HT29 Cells; Humans; Mice; Mice, Nude; Neoplasms; Xenograft Model Antitumor Assays | 2014 |
Characterization of the activity of 2'-C-methylcytidine against dengue virus replication.
Topics: Animals; Antiviral Agents; Biological Assay; Chlorocebus aethiops; Cytidine; Dengue; Dengue Virus; Disease Models, Animal; Mice; Replicon; RNA, Viral; Transplantation, Heterologous; Vero Cells; Virus Replication | 2015 |
DNA Methylation Inhibitor Zebularine Confers Stroke Protection in Ischemic Rats.
Topics: Analysis of Variance; Animals; Brain Infarction; Cytidine; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Infarction, Middle Cerebral Artery; Male; Rats; Rats, Wistar; Reperfusion | 2015 |
Treatment with a Nucleoside Polymerase Inhibitor Reduces Shedding of Murine Norovirus in Stool to Undetectable Levels without Emergence of Drug-Resistant Variants.
Topics: Amides; Animals; Caliciviridae Infections; Cytidine; Disease Models, Animal; Feces; Gastroenteritis; Mice; Mice, Knockout; Norovirus; Pyrazines; Receptors, Interferon; Transplant Recipients; Virus Shedding | 2015 |
Cyclopentenyl cytosine has biological and anti-tumour activity, but does not enhance the efficacy of gemcitabine and radiation in two animal tumour models.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Combined Modality Therapy; Cytidine; Cytidine Triphosphate; Deoxycytidine; Disease Models, Animal; Drug Synergism; Female; Gemcitabine; Humans; Lung Neoplasms; Mice; Mice, Nude; Middle Aged; Pancreatic Neoplasms; Rats; Rats, Inbred BN | 2009 |
CDP-choline and its endogenous metabolites, cytidine and choline, promote the nerve regeneration and improve the functional recovery of injured rat sciatic nerves.
Topics: Administration, Cutaneous; Animals; Choline; Cytidine; Cytidine Diphosphate Choline; Disease Models, Animal; Female; Nerve Regeneration; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Recovery of Function; Sciatic Neuropathy; Trauma Severity Indices | 2011 |
DNA methyltransferase inhibitor, zebularine, delays tumor growth and induces apoptosis in a genetically engineered mouse model of breast cancer.
Topics: Administration, Oral; Animals; Antigens, Polyomavirus Transforming; Apoptosis; Breast Neoplasms; Cytidine; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Immunoblotting; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Transgenic; Necrosis; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; Tumor Burden | 2012 |
Intraperitoneal administration of CDP-choline or a combination of cytidine plus choline improves nerve regeneration and functional recovery in a rat model of sciatic nerve injury.
Topics: Animals; Axotomy; Choline; Cytidine; Cytidine Diphosphate Choline; Disease Models, Animal; Drug Therapy, Combination; Female; Injections, Intraperitoneal; Nerve Regeneration; Nootropic Agents; Rats; Rats, Sprague-Dawley; Recovery of Function; Sciatic Nerve; Sciatic Neuropathy | 2012 |
Mouse model of endemic Burkitt translocations reveals the long-range boundaries of Ig-mediated oncogene deregulation.
Topics: Animals; B-Lymphocytes; Burkitt Lymphoma; Cells, Cultured; Cytidine; Disease Models, Animal; Endemic Diseases; Enhancer Elements, Genetic; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gene Rearrangement, B-Lymphocyte; Genes, Immunoglobulin Heavy Chain; Genes, myc; Humans; Immunoglobulin Class Switching; Mice; Oncogene Proteins, Fusion; Plasma Cells; Transcription Initiation Site; Translocation, Genetic; Uracil-DNA Glycosidase | 2012 |
The in vitro and in vivo effects of re-expressing methylated von Hippel-Lindau tumor suppressor gene in clear cell renal carcinoma with 5-aza-2'-deoxycytidine.
Topics: Adenocarcinoma, Clear Cell; Animals; Antimetabolites, Antineoplastic; Azacitidine; Cytidine; Decitabine; Disease Models, Animal; DNA Methylation; Gene Silencing; Humans; Kidney Neoplasms; Mice; Pyrimidine Nucleosides; Reverse Transcriptase Polymerase Chain Reaction; Transfection; Transplantation, Heterologous; Tumor Cells, Cultured; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases; Von Hippel-Lindau Tumor Suppressor Protein | 2004 |
Absence of cardiotoxicity of the experimental cytotoxic drug cyclopentenyl cytosine (CPEC) in rats.
Topics: Animals; Annexin A5; Antineoplastic Agents; Apoptosis; Cardiomyopathies; Cytidine; Disease Models, Animal; Heart; Heart Atria; In Situ Nick-End Labeling; Male; Myocardial Contraction; Myocardium; Organotechnetium Compounds; Rats; Rats, Wistar; Tomography, Emission-Computed, Single-Photon; Troponin T | 2005 |
Peripheral administration of CDP-choline, phosphocholine or choline increases plasma adrenaline and noradrenaline concentrations.
Topics: Adrenal Glands; Animals; Atropine Derivatives; Autonomic Nervous System; Central Nervous System; Choline; Cytidine; Cytidine Diphosphate Choline; Cytidine Monophosphate; Disease Models, Animal; Dose-Response Relationship, Drug; Epinephrine; Female; Hemorrhage; Hexamethonium; Injections, Intraperitoneal; Injections, Intraventricular; Mecamylamine; Nicotinic Antagonists; Norepinephrine; Phosphorylcholine; Rats; Rats, Wistar; Time Factors | 2008 |
Long term prevention of allergic lung inflammation in a mouse model of asthma by CpG oligodeoxynucleotides.
Topics: Allergens; Animals; Anti-Allergic Agents; Asthma; Chemotaxis, Leukocyte; Cytidine; Dinucleoside Phosphates; Disease Models, Animal; Female; Guanosine; Immunoglobulin E; Interferon-gamma; Interleukin-4; Mice; Mice, Inbred BALB C; Mice, Mutant Strains; Nebulizers and Vaporizers; Oligodeoxyribonucleotides; Plant Proteins; Pollen; Pulmonary Eosinophilia; Th1 Cells; Th2 Cells; Time Factors; Trachea | 1999 |
Maedi-visna virus, a model for in vitro testing of potential anti-HIV drugs.
Topics: Animals; Anti-HIV Agents; Cells, Cultured; Cytidine; Cytopathogenic Effect, Viral; Disease Models, Animal; Dose-Response Relationship, Drug; Sheep; Viral Load; Virus Replication; Visna-maedi virus; Zalcitabine | 2001 |
Degradative enzyme systems in osteoarthritic cartilage.
Topics: Acid Phosphatase; Animals; Cartilage, Articular; Cytidine; Disease Models, Animal; Edetic Acid; Egtazic Acid; Endopeptidases; Glycosaminoglycans; Humans; Hydrogen-Ion Concentration; Metalloendopeptidases; Microbial Collagenase; Osteoarthritis; Rabbits; Thymidine | 1985 |
Prolonged carotid arterial radiosensitizer infusion and radiation therapy of mouse gliomas.
Topics: Animals; Brain Neoplasms; Bromine; Carotid Arteries; Catheterization; Craniotomy; Cytidine; Deoxyribonucleosides; Disease Models, Animal; DNA; Floxuridine; Glioma; Injections, Intra-Arterial; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Radiation-Sensitizing Agents; Sodium Chloride; Thymidine; Time Factors; Transplantation, Homologous | 1972 |