Page last updated: 2024-08-17

cytidine and Cancer of Pancreas

cytidine has been researched along with Cancer of Pancreas in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (42.86)29.6817
2010's3 (21.43)24.3611
2020's5 (35.71)2.80

Authors

AuthorsStudies
Enoki, Y; Imoto, S; Ito, C; Matsumoto, K; Moroi, Y; Taguchi, K; Tokuda, R; Yamasaki, K1
Chen, H; Feng, Z; Han, D; Jiang, L; Li, K; Liang, H; Liang, J; Ma, Y; Peng, C; Qin, K; Shen, B; Shi, M; Zhao, S1
Leung, E; Lozano Hernandez, L; Reginald-Opara, JN; Svirskis, D; Tang, M; Wang, H; Wu, Z1
Bhutkar, S; Dukhande, V; Patel, K; Patki, M; Saraswat, A1
Babiker, H; Benaim, E; Borad, MJ; Bullock, AJ; Burhani, N; Elquza, E; Heaton, C; Hicks, LG; Mahadevan, D; Ocean, AJ; Peterson, C; Schlegel, PJ1
An, Y; Cai, H; Chen, X; Duan, Y; Liu, S; Sun, D; Wu, X; Yang, Y; Zhang, Y1
El Hassouni, B; Funel, N; Giovannetti, E; Infante, J; Mantini, G; Peters, GJ; Ricci, C1
Fritzer-Szekeres, M; Giessrigl, B; Golakoti, T; Graser, G; Grusch, M; Jaeger, W; Krupitza, G; Lackner, A; Saiko, P; Schuster, H; Somepalli, V; Steinmann, MT; Szekeres, T1
Angel, A; Congiatu, C; Gavazza, F; Jones, PA; Marquez, VE; McGuigan, C; Siddiqui, MA; Valente, R; Yoo, CB1
Barten-Van Rijbroek, AD; Kal, HB; Leen, R; Rodermond, HM; Van Bree, C; Van Kuilenburg, AB1
Fujioka, A; Fukushima, M; Kazuno, H; Matsuda, A; Sakamoto, K; Sasaki, T1
Dietze, O; Hahn, EG; Hauser-Kronberger, C; Herold, C; Leu, T; Neureiter, D; Ocker, M; Zopf, S1
Leen, R; Medema, J; Rodermond, H; van Bree, C; van Kuilenburg, A1
Fujioka, A; Fukushima, M; Kato, T; Kazuno, H; Matsuda, A; Murakami, Y; Ohshimo, H; Sasaki, T; Shimamoto, Y1

Trials

1 trial(s) available for cytidine and Cancer of Pancreas

ArticleYear
A multicenter phase 1/2 study investigating the safety, pharmacokinetics, pharmacodynamics and efficacy of a small molecule antimetabolite, RX-3117, plus nab-paclitaxel in pancreatic adenocarcinoma.
    Investigational new drugs, 2022, Volume: 40, Issue:1

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Albumins; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Cytidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Half-Life; Humans; Male; Maximum Tolerated Dose; Metabolic Clearance Rate; Middle Aged; Paclitaxel; Pancreatic Neoplasms

2022

Other Studies

13 other study(ies) available for cytidine and Cancer of Pancreas

ArticleYear
Trimethoxy Trityl Groups as a Potent Substituent for Anti-cancer Cytidine Analog Prodrugs.
    Journal of pharmaceutical sciences, 2022, Volume: 111, Issue:8

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cytidine; Humans; Mice; Pancreatic Neoplasms; Prodrugs

2022
The LINC00623/NAT10 signaling axis promotes pancreatic cancer progression by remodeling ac4C modification of mRNA.
    Journal of hematology & oncology, 2022, 08-17, Volume: 15, Issue:1

    Topics: Acetyltransferases; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cytidine; Gene Expression Regulation, Neoplastic; Humans; N-Terminal Acetyltransferases; Neoplasm Invasiveness; Pancreatic Neoplasms; RNA, Long Noncoding; RNA, Messenger; Ubiquitin-Specific Proteases

2022
Zebularine suppressed gemcitabine-induced senescence and improved the cellular and plasma pharmacokinetics of gemcitabine, augmented by liposomal co-delivery.
    International journal of pharmaceutics, 2021, Jun-01, Volume: 602

    Topics: Animals; Cell Line, Tumor; Cytidine; Deoxycytidine; Drug Resistance, Neoplasm; Gemcitabine; Liposomes; Pancreatic Neoplasms; Rats

2021
In vitro assessment of a synergistic combination of gemcitabine and zebularine in pancreatic cancer cells.
    Experimental cell research, 2021, 08-15, Volume: 405, Issue:2

    Topics: Antimetabolites, Antineoplastic; Apoptosis Regulatory Proteins; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cytidine; Cytidine Deaminase; Deoxycytidine; Gemcitabine; Humans; Pancreas; Pancreatic Neoplasms

2021
Identification of ENTPD8 and cytidine in pancreatic cancer by metabolomic and transcriptomic conjoint analysis.
    Cancer science, 2018, Volume: 109, Issue:9

    Topics: Adenosine Triphosphatases; Adult; Aged; Aged, 80 and over; Cell Line, Tumor; Cytidine; Female; Gene Expression Profiling; Humans; Male; Metabolomics; Middle Aged; Pancreatic Neoplasms

2018
Uridine Cytidine Kinase 2 as a Potential Biomarker for Treatment with RX-3117 in Pancreatic Cancer.
    Anticancer research, 2019, Volume: 39, Issue:7

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Biomarkers, Tumor; Cell Line, Tumor; Cytidine; Female; Humans; Male; Pancreatic Neoplasms; RNA, Messenger; Uridine Kinase

2019
Digalloylresveratrol, a novel resveratrol analog inhibits the growth of human pancreatic cancer cells.
    Investigational new drugs, 2013, Volume: 31, Issue:5

    Topics: Antineoplastic Agents; Biphenyl Compounds; Cell Cycle; Cell Line, Tumor; Cytidine; DNA; Free Radical Scavengers; Gallic Acid; Humans; Mitogen-Activated Protein Kinases; Pancreatic Neoplasms; Picrates; Proto-Oncogene Mas; Ribonucleotide Reductases; Stilbenes

2013
Activation of p16 gene silenced by DNA methylation in cancer cells by phosphoramidate derivatives of 2'-deoxyzebularine.
    Journal of medicinal chemistry, 2008, Dec-11, Volume: 51, Issue:23

    Topics: Adenocarcinoma; Amides; Cytidine; DCMP Deaminase; DNA Methylation; Dose-Response Relationship, Drug; Gene Silencing; Genes, p16; Humans; Molecular Structure; Pancreatic Neoplasms; Phosphoric Acids; Reverse Transcriptase Polymerase Chain Reaction; Stereoisomerism; Thymidylate Synthase; Tumor Cells, Cultured

2008
Cyclopentenyl cytosine has biological and anti-tumour activity, but does not enhance the efficacy of gemcitabine and radiation in two animal tumour models.
    International journal of oncology, 2009, Volume: 34, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Combined Modality Therapy; Cytidine; Cytidine Triphosphate; Deoxycytidine; Disease Models, Animal; Drug Synergism; Female; Gemcitabine; Humans; Lung Neoplasms; Mice; Mice, Nude; Middle Aged; Pancreatic Neoplasms; Rats; Rats, Inbred BN

2009
Possible antitumor activity of 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine (ECyd, TAS-106) against an established gemcitabine (dFdCyd)-resistant human pancreatic cancer cell line.
    Cancer science, 2005, Volume: 96, Issue:5

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cytidine; Deoxycytidine; Deoxyribonucleotides; Drug Resistance, Neoplasm; Gemcitabine; Humans; Inhibitory Concentration 50; Male; Mice; Mice, Nude; Pancreatic Neoplasms; Ribonucleotides; RNA, Messenger; Xenograft Model Antitumor Assays

2005
Apoptosis, proliferation and differentiation patterns are influenced by Zebularine and SAHA in pancreatic cancer models.
    Scandinavian journal of gastroenterology, 2007, Volume: 42, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Cell Differentiation; Cell Proliferation; Cytidine; DNA, Neoplasm; Epigenesis, Genetic; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Immunohistochemistry; Male; Mice; Mice, Nude; Neoplasm Proteins; Pancreatic Neoplasms; Tumor Cells, Cultured; Vorinostat

2007
Cyclopentenyl cytosine increases gemcitabine radiosensitisation in human pancreatic cancer cells.
    British journal of cancer, 2008, Apr-08, Volume: 98, Issue:7

    Topics: Apoptosis; Cell Line, Tumor; Cell Survival; Cytidine; Cytidine Triphosphate; Deoxycytidine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Gemcitabine; Humans; Lung Neoplasms; Pancreatic Neoplasms; Radiation Tolerance; Radiation-Sensitizing Agents

2008
Antitumor activity and pharmacokinetics of TAS-106, 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine.
    Japanese journal of cancer research : Gann, 2001, Volume: 92, Issue:3

    Topics: Animals; Antimetabolites, Antineoplastic; Breast Neoplasms; Cell Survival; Colonic Neoplasms; Cytidine; Female; Humans; Lung Neoplasms; Male; Pancreatic Neoplasms; Rats; Rats, Inbred F344; Rats, Nude; Stomach Neoplasms; Tissue Distribution; Transplantation, Heterologous; Tumor Cells, Cultured

2001