cytarabine has been researched along with Leukemia in 1245 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 853 (68.51) | 18.7374 |
| 1990's | 160 (12.85) | 18.2507 |
| 2000's | 136 (10.92) | 29.6817 |
| 2010's | 84 (6.75) | 24.3611 |
| 2020's | 12 (0.96) | 2.80 |
| Authors | Studies |
|---|---|
| Watkins, WM | 1 |
| Chou, TH; Kessel, D; Khilanani, P; Lomen, PL | 1 |
| Matsuda, A; Sasaki, T; Takenuki, K; Ueda, T | 1 |
| McIntee, EJ; Wagner, CR | 1 |
| Addo, SN; Das, SG; Doshi, JM; Hermanson, DL; Srinivasan, B; Tian, D; Xing, C | 1 |
| Chen, Y; Ding, Y; Guo, J; Ivanov, I; Li, J; Li, KK; Li, L; Li, Q; Li, S; Liu, N; Long, H; Long, J; Luo, M; Ma, C; Wang, PG; Wen, L; Wu, Z; Xi, R; Xue, Q; Yan, C; Zhang, Q; Zhao, C; Zhu, H | 1 |
| Fischer, AS; Kersh, AE; Rosenbach, M; Shields, BE; Torre, EA; Xu, X | 1 |
| Cabot, MC; Claxton, DF; Coalson, HS; Feith, DJ; Fisher-Wellman, KH; Fox, TE; Hagen, JT; Kao, LP; Kassai, M; Kester, M; Loughran, TP; McLaughlin, KL; Nelson, MAM; Tan, SF | 1 |
| Xiang, R; Yi, J | 1 |
| Chen, X; Gao, XH; Hao, HL; Huang, C; Li, J; Li, JY; Li, Y; Liu, JY; Tu, CQ; Wang, DW; Wang, RC; Xiong, X; Yang, J; Yang, YB; Yuan, J; Zhang, XX; Zhang, XY; Zheng, CF; Zou, LL | 1 |
| Chorna, N; Diaz-Quiñones, AO; Maldonado, HM; Ortiz, WIS; Rodríguez-Vázquez, GO; Salgado-Villanueva, IK; Tang, J | 1 |
| Alexander, TB; Galeotti, J; Hucks, G; Sperlazza, J | 1 |
| Basile, P; Ebadi, M; Gordon, PM; Johnson, K; Jonart, LM; Makori, J | 1 |
| Beutel, G; Dammann, E; Eder, M; Eggers, H; Ehrlich, S; Gabdoulline, R; Ganser, A; Göhring, G; Hambach, L; Heuser, M; Klement, P; Koenecke, C; Markel, D; Neziri, B; Rehberg, A; Reuter, M; Schlegelberger, B; Shahswar, R; Stadler, M; Thol, F; Wichmann, M | 1 |
| Kolb, HJ; Schmid, C | 1 |
| Cerchione, C; Martinelli, G | 1 |
| Arai, S; Ikegawa, M; Kamikubo, Y; Kurokawa, M; Maki, H; Morita, K; Shimada, T; Yoshimi, A | 1 |
| Akhtar, N; Britton, D; Casado, P; Cutillas, PR; Dokal, A; Fitzgibbon, J; Gerdes, H; Hijazi, M; Khorsandi, S; Osuntola, R; Rajeeve, V; Travers, J | 1 |
| Bechara, A; Bincoletto, C; Calgarotto, AK; Erustes, AG; Garcia, DM; Lima, CS; Michelin, LFG; Oliveira, CR; Palmeira-Dos-Santos, C; Paredes-Gamero, E; Peixoto-da-Silva, J; Pereira, GJS; Smaili, SS; Spindola, DG | 1 |
| Blijlevens, NMA; Kox, M; Leijte, GP; Pickkers, PP; Scheffer, GJ; Timmermans, K | 1 |
| Sonmez, M; Yucel, B | 1 |
| Dünweber, A; Fridthjof, KS; Friis, LS; Gørløv, JS; Kampmann, P; Kjeldsen, L; Moser, C; Møller, T; Nexø, C; Nørskov, KH; Welinder, PC | 1 |
| Arcangeli, A; Bernini, A; Bracci, L; Lelli, B; Niccolai, N; Petroni, G; Pillozzi, S; Spiga, O | 1 |
| Bridges, AG; El-Azhary, RA; Hashmi, SK; Hunjan, MK; Lehman, JS; Nowsheen, S; Ramos-Rodriguez, AJ | 1 |
| Farooq, A; Farooq, MU; Khan, DH; Mir, MA; Mushtaq, F | 1 |
| Aladjidi, N; Auperin, A; Couec, ML; Gandemer, V; Haouy, S; Jourdain, A; Lambliotte, A; Landman-Parker, J; Leblanc, T; Michon, J; Minard-Colin, V; Patte, C; Plat, G; Rigaud, C | 1 |
| Alloush, H; Anderson, E; Conway, M; Lamont, J; Martin, A; Mehta, P; Ruddock, M; Salisbury, V; Smith, JG; Smith, MA | 1 |
| Brennig, S; Dilloo, D; Flasshove, M; Lachmann, N; Moritz, T; Phaltane, R | 1 |
| Chen, J; Fu, J; Huang, B; Liang, A; Lu, H; Xiong, H; Xiu, B; Zhang, W | 1 |
| Arioka, Y; Funato, T; Hara, T; Kawasoe, M; Markey, SP; Matsunami, H; Moriwaki, H; Okawa, K; Saito, K; Takeda, M; Takemura, M; Tsurumi, H; Yamamoto, Y | 1 |
| Chan, TS; Chim, CS; Gill, H; Hwang, YY; Kwong, YL; Leung, AY; Lie, AK; Tse, E | 1 |
| Aljitawi, OS; Garimella, R; Kambhampati, S; Li, D; Lin, TL; Ramachandran, K; Stehno-Bittel, L; Van Veldhuizen, P; Xiao, Y; Zhang, D | 1 |
| Reese, ND; Schiller, GJ | 1 |
| Asano, S; Chen, MH; Izawa, K; Kobayashi, S; Maruyama, K; Soda, Y; Tani, K; Tojo, A | 1 |
| Cheng, J; Lu, Y; Lv, Y; Mitchelson, K; Xing, W; Xu, Y; Zeng, L; Zhang, G | 1 |
| Cheng, J; Fan, D; Li, W; Li, Z; Shi, R; Wang, J; Xiong, D; Yan, Y; Yang, M; Zhang, M | 1 |
| Carpi, FM; Costanzi, S; Micozzi, D; Polidori, P; Polzonetti, V; Pucciarelli, S; Vilar, S; Vincenzetti, S; Williams, B | 1 |
| Barbosa, CM; Bincoletto, C; Jurkiewicz, A; Palmeira dos Santos, C; Pereira, GJ; Smaili, SS | 1 |
| Arsikin, K; Bogdanovic, A; Bosnjak, M; Bumbasirevic, V; Harhaji-Trajkovic, L; Markovic, I; Mircic, A; Paunovic, V; Perovic, V; Ristic, B; Suzin-Zivkovic, V; Trajkovic, V | 1 |
| Huang, GN; Jia, DY; Liu, J; Mu, XY; Wang, YP; Xu, CY; Zhang, MS; Zhang, YY; Zhu, JH | 1 |
| Dong, B; Huang, H; Qu, L; Weng, H; Zhao, P; Zhou, H | 1 |
| Beck, J; Burmeister, T; Dengler, J; Döhner, H; Domanska-Czyz, K; Dührsen, U; Fietkau, R; Gökbuget, N; Hertenstein, B; Hiddemann, W; Hoelzer, D; Horst, HA; Hüttmann, A; Kneba, M; Reichle, A; Rieder, H; Schaich, M; Schmidt-Wolf, IG; Schwartz, S; Serve, H; Spiekermann, K; Thiel, E; Viardot, A; Walewski, J | 1 |
| Kotsianidis, I; Tsatalas, C | 1 |
| Fondy, TP; Trendowski, M; Wong, V; Yu, G | 1 |
| Liu, SH; Lu, W; Shi, J; Wan, Y; Wang, H; Zhai, YM; Zhu, XY | 1 |
| Kong, P; Li, J; Ma, Y; Shen, Z; Zeng, D; Zhang, C; Zhang, X; Zhu, L; Zou, Z | 1 |
| Ikezoe, T; Nishioka, C; Yokoyama, A | 1 |
| Costanzo, P; Drott, K; Gullberg, U; Jernmark-Nilsson, H; Montano, G; Sodaro, G; Ullmark, T; Vidovic, K | 1 |
| Bruheim, S; Suo, Z; Wendel, T; Wiedlocha, A; Zhen, Y | 1 |
| Brand, P; Cairo, MS; Fabricatore, S; Harrison, L; Hochberg, J; Militano, O; Morris, E; Wolownik, K | 1 |
| Gerber, JM; Grunwald, MR; Induru, R; McDonnell, MH | 1 |
| Kong, PY; Ma, YY; Shen, ZH; Zeng, DF; Zhang, X | 1 |
| Hayakawa, F; Kato, H; Miyata, Y; Mizuno, H; Nakayama, T; Naoe, T; Nishiwaki, S; Saito, S; Sugimoto, K; Suzuki, R; Takami, A; Takeshita, K; Ueda, R | 1 |
| Appelhans, D; Klajnert-Maculewicz, B; Pulaski, L; Szulc, A; Voit, B | 1 |
| Cao, J; Chen, C; Chen, W; Ding, NN; Feng, H; Niu, MS; Qiu, TT; Wu, QY; Xu, KL; Zhu, HH | 1 |
| Azevedo, EA; Coelho-Silva, JL; Franca, RF; Franca-Neto, PL; Hemmelgarn, BT; Krause, A; Lange, AP; Lucena-Araujo, AR; Morais-Sobral, MC; Paiva, HH; Pereira-Martins, DA; Rego, EM; Scheucher, PS; Silva, CL; Thomé, C | 1 |
| Bajwa, RPS; Gerhardt, CA; Hagedoorn, M; Keim, MC; Lehmann, V; Olshefski, RS; Tuinman, MA; Winning, AM | 1 |
| Fan, DM; Gao, YD; Ji, Q; Jia, HR; Wang, JH; Xiong, DS; Yang, CZ; Yang, M | 1 |
| Bhojwani, D; Pui, CH | 1 |
| Deeren, D | 1 |
| Chen, XW; Li, CG; Li, CR; Shi, HS; Yue, LJ; Zhang, M | 1 |
| Cinatl, J; Doerr, HW; Klassert, D; Michaelis, M; Ogbomo, H | 1 |
| Jiang, SY; Li, BS; Xie, XT; Yang, LL | 1 |
| Behrendt, CE; Gehan, EA | 1 |
| Barretto, NN; Bennett, CA; Hemenway, CS; Winters, AC | 1 |
| Aimiuwu, J; Blum, W; Chan, KK; Chen, P; Grever, MR; Klisovic, R; Liu, S; Liu, Z; Marcucci, G; Pang, J; Xie, Z | 1 |
| Hofheinz, RD; Kripp, M | 1 |
| Hong, M; Li, JY; Qian, SX; Qiu, HX; Wu, HX; Xu, W; Zhang, R | 1 |
| Angelucci, E; Murru, R; Pettinau, M; Romani, C | 1 |
| Chen, ZC; Li, L; Li, QB; Xia, LH; You, Y; Zou, P | 1 |
| Einsele, H; Grigoleit, GU; Kapp, M; Mielke, S; Stuhler, G; Tan, SM; Topp, MS; Unzicker, C | 1 |
| Faderl, S | 1 |
| Akutsu, M; Furukawa, Y; Izumi, T; Kano, Y; Mano, H; Miyawaki, S; Tanaka, M; Tsunoda, S; Yazawa, Y | 1 |
| Andreeff, M; Bornmann, W; Duvvuri, S; Fiegl, M; Harmancey, R; Kaluarachchi, K; Kantarjian, H; Konopleva, M; Korchin, B; Samudio, I; Taegtmeyer, H | 1 |
| Chan, TH; Davenport, A; Dou, QP; Frezza, M; Ge, Y; Huo, C; Shen, M | 1 |
| Fan, DM; Gao, YD; Ji, Q; Shao, XF; Wang, JH; Xiong, DS; Xu, YF; Yang, CZ; Yang, M; Zhou, Y | 1 |
| Keating, A; Wang, XH; Williams, BA | 1 |
| Ishigatsubo, Y; Kanamoari, H; Maruta, A; Tachibana, T; Takasaki, H; Tanaka, M | 1 |
| Adema, AD; Kathmann, I; Losekoot, N; Myhren, F; Peters, GJ; Sandvold, ML; Smid, K | 1 |
| Hsu, CH; Liu, CI | 1 |
| Carlo-Stella, C; Delia, D; Drago, C; Lambertenghi Deliliers, G; Lecis, D; Manzoni, L; Onida, F; Polli, E; Scavullo, C; Seneci, P; Servida, F | 1 |
| Batey, RA; Datti, A; Fonseca, SB; Gronda, M; Hurren, R; Kelley, SO; Minden, MD; Schimmer, AD; Sharmeen, S; Skrtic, M; Sukhai, MA; Sun, H; Wang, X; Ward, R; Wood, TE; Wrana, J | 1 |
| Altman, JK; Fukunaga, R; Glaser, H; Joshi, S; Platanias, LC; Sassano, A; Tallman, MS; Ueda, T; Watanabe-Fukunaga, R | 1 |
| Asano, S; Funayama, K; Murai, F; Nomura, H; Shimane, M | 1 |
| Chhikara, BS; Mandal, D; Parang, K | 1 |
| Cho, SY; Huh, J; Jun, KR; Kim, B; Kim, HR; Kim, MJ; Lee, JN; Lee, JY; Oh, SH; Park, TS; Shin, JH; Song, SA | 1 |
| Reilly, AF; Rheingold, SR; Seif, AE | 1 |
| Chhikara, BS; Parang, K | 1 |
| Faderl, S; Ghandhi, V; Ghanem, H; Jabbour, E; Kantarjian, H; Plunkett, W | 1 |
| DA, WM; Lu, DP; Luo, RM; Sun, Y; Tong, CR; Wang, JB; Wei, ZJ; Wu, T; Zhang, JP; Zhang, WJ; Zhao, YL | 1 |
| Hara, T; Kanemura, N; Kasahara, S; Kitagawa, J; Moriwaki, H; Shimizu, M; Tsurumi, H | 1 |
| Brion, A; Chauchet, A; Daguindau, E; Deconinck, E; Delaby, P; Fontan, J; Garnache-Ottou, F; Heczko, M; Helias, P; Larosa, F; Legrand, F; Schillinger, F; Vuillier, J | 1 |
| Alino, K; Bagain, L; Blackford, A; Briel, J; Carraway, H; Doyle, LA; Gore, SD; Greer, JM; Joseph, B; Karp, JE; Levis, MJ; Mackey, K; McDevitt, MA; Moton-Nelson, D; Resar, LS; Rudek, MA; Smith, BD; Wright, JJ; Zhao, M | 1 |
| Hori, H; Negoro, E; Nishi, R; Ueda, T; Urasaki, Y; Yamauchi, T | 1 |
| Chastagner, P; Clement, L; Contet, A; Kimmoun, A; Salmon, A; Schmitt, C; Sudour, H | 1 |
| Gottschalk, M; Lawson, EB; Schiff, DE | 1 |
| Allan, JM; Fordham, SE; Irving, JA; Matheson, EC; Scott, K | 1 |
| Hirabayashi, K; Ishii, E; Koike, K; Nakamura, T; Saito, S; Sakashita, K; Shiohara, M; Takahashi, D; Tanaka, M; Yanagisawa, R | 1 |
| Baker, SD; Campana, D; Christensen, R; Coustan-Smith, E; Furmanski, BD; Heym, KM; Inaba, H; Li, L; Mascara, GP; Onciu, M; Pounds, SB; Pui, CH; Ribeiro, RC; Rubnitz, JE; Shurtleff, SA | 1 |
| Adjei, AA; Ames, MM; Chen, Y; Erlichman, C; Flatten, KS; Greer, J; Hogan, W; Ivy, SP; Karnitz, LM; Karp, JE; Kaufmann, SH; Litzow, MR; Loegering, DA; Maurer, MJ; Mesa, RA; Peterson, KL; Reid, JM; Schneider, PA; Smith, BD; Steensma, DP | 1 |
| Shigematsu, A | 1 |
| Chuttani, K; Jacob, S; Mishra, AK; Sachdeva, G; Sawant, KK; Yadav, KS | 1 |
| Adema, AD; Honeywell, RJ; Losekoot, N; Myhren, F; Peters, GJ; Sandvold, ML; Smid, K; Verheul, HM | 1 |
| Dube, B; Sawant, K; Sharma, P | 2 |
| Fritzer-Szekeres, M; Golakoti, T; Graser, G; Jaeger, W; Krupitza, G; Madlener, S; Saiko, P; Schwarz, S; Somepalli, V; Szekeres, T | 1 |
| Chen, ZT; Kong, PY; Li, DZ; Li, GH; Sun, JG; Wang, XX; Zhou, YB | 1 |
| Liu, X; Wan, Q; Xi, A; Zhang, C | 1 |
| Albiero, E; Bernardi, M; Castegnaro, S; Chieregato, K; Madeo, D; Rodeghiero, F; Visco, C; Zanon, C | 1 |
| Braess, J; Holdenrieder, S; Kolligs, FT; Manukyan, D; Stieber, P | 1 |
| Ceruti, M; Cosco, D; Fresta, M; Paolino, D; Rocco, F; Vono, M | 1 |
| Ambinder, RF; Bolaños-Meade, J; Borowitz, MJ; Brodsky, RA; Carraway, HE; Cho, SY; Crilley, PA; Gladstone, DE; Huff, CA; Jones, RJ; Kasamon, YL; Matsui, WH; Smith, BD; Swinnen, LJ; Tsai, HL | 1 |
| Chiarella, MT; Feldman, EJ; Kolitz, JE; Lancet, JE; Liboiron, BD; Louie, AC; Mayer, LD; Swenson, CE; Trang, JM | 1 |
| Davis, S; Granier, CJ; Kokorina, NA; Rabson, AB; Sabaawy, HE; Zakharkin, SO | 1 |
| Borne, J; Jankowski, G; Nevarez, JG; Sirninger, J | 1 |
| Zyrina, GV | 1 |
| Jiang, B; Qu, YN; Wang, YH | 1 |
| Giles, FJ | 1 |
| Ono, R | 1 |
| Akutsu, M; Furukawa, Y; Izumi, T; Kano, Y; Ohmine, K; Tsunoda, S | 1 |
| Balduzzi, A; Biondi, A; Bonanomi, S; Dassi, M; Gaipa, G; Perseghin, P; Rovelli, A; Uderzo, C | 1 |
| Bezombes, C; Jaffrézou, JP; Laurent, G; Lerouge, S; Terrisse, AD | 1 |
| Balcerzak, SP; Bloomfield, CD; Byrd, JC; Caligiuri, MA; Cataland, SR; Chan, KK; Dai, G; Farag, SF; Fisher, DB; Frankel, SR; Grever, MR; Klisovic, MI; Kourlas, PJ; Kraut, EH; Lin, ZP; Lucas, D; Marcucci, G; Porcu, P; Young, DC; Zwiebel, JA | 1 |
| He, DM; Lei, XY; Zhang, H | 1 |
| Burgin, AB; Chrencik, JE; Pommier, Y; Redinbo, MR; Stewart, L | 1 |
| Liu, Z; Xiao, J; Zou, P | 1 |
| Ito, T; Koizumi, S; Maeba, H; Nishimura, R; Ota, K; Saikawa, Y; Sasaki, T; Tanaka, M; Uehara, T; Yue, L | 1 |
| Barge, RM; Honders, MW; Spoelder, HE; Veuger, MJ; Willemze, R | 1 |
| Buatti, J; deMagalhaes-Silverman, M; Gingrich, RD; Hayashi, M; Hohl, RJ; Lee, CK; Schlueter, A; Strauss, RG; Wen, BC | 1 |
| Lei, XY; Zhang, Y | 1 |
| Fukuda, T; Ghazizadeh, M; Kawanami, O; Nagashima, M; Shimizu, H; Suzuki, T | 1 |
| Dai, Y; Decker, RH; Grant, S; Kramer, LB; Levin, J | 1 |
| Begum, G; Craddock, CF; Craig, JI; Duncan, N; Mahendra, P; Marcus, RE; Nitu-Whalley, IC; Shankaranarayana, P; Tauro, S | 1 |
| Huang, XJ; Lu, DP; Lu, J | 1 |
| Akiyama, T; Fujimi, A; Hirayama, Y; Kato, J; Kawano, Y; Kobune, M; Kohda, K; Kuroda, H; Matsunaga, T; Miyake, K; Niitsu, Y; Sakamaki, S; Sato, T; Takemoto, N; Takimoto, R; Tanaka, I | 1 |
| Bramwell, V; Crump, M; Levine, M; Pritchard, K; Shepherd, L; Tu, D | 1 |
| Cox, J; Johnson, L; Lickliter, JD; McHugh, G; Tan, J; Wickham, NW; Wood, F; Wood, NJ | 1 |
| Asou, N; Horikawa, K; Koh, Y; Matsuno, F; Mitsuya, H; Nakamura, M; Tajiri, T; Tatetsu, H; Yonemura, Y | 1 |
| Frankel, MC; Georgala, S; Itakura, H; Junkins-Hopkins, JM; Rook, AH; Schuster, SJ; Shapiro, M; Vittorio, CC; Wasik, MA | 1 |
| BOSTWICK, L; EVANS, JS; MENGEL, GD | 1 |
| EVANS, JS; MENGEL, GD | 1 |
| CHU, MY; FISCHER, GA | 1 |
| Wang, LL; Xu, CG; Zhang, MH | 1 |
| Flatley, RM; Ge, Y; Grohar, PJ; Jensen, TL; Matherly, LH; Ravindranath, Y; Stout, ML; Taub, JW | 1 |
| Kimura, S; Kuroda, J; Maekawa, T; Nogawa, M; Ottmann, OG; Sato, K; Segawa, H; Yuasa, T | 1 |
| Corazza, F; Harfi, I; Hayez, N; Lema-Kisoka, R; Sariban, E; Svoboda, M | 1 |
| Bergman, AM; Comijn, EM; Hendriks, HR; Kuiper, CM; Myhren, F; Peters, GJ; Sandvold, ML; Voorn, DA | 1 |
| Agazzi, A; Bertolini, F; Calabrese, L; Cinieri, S; Cocquio, A; Goldhirsch, A; Laszlo, D; Martinelli, G; Pruneri, G; Rabascio, C | 1 |
| Bornhäuser, M; Braess, J; Ehninger, G; Freiberg-Richter, J; Illmer, T; Köhne, Ch; Le Coutre, P; Ottmann, OG; Platzbecker, U; Pursche, J; Schaich, M; Schleyer, E; Thiede, C; von Bonin, M | 1 |
| Billi, AM; Bortul, R; Cocco, L; Conte, R; Manzoli, L; Martelli, AM; Tabellini, G; Tazzari, PL | 1 |
| Asou, K; Higurashi, A; Ishikawa, M; Kanno, S; Shouji, A; Watanabe, Y | 1 |
| Bainbridge, T; Cherrington, JM; Heinrich, MC; McGreevey, L; O'Farrell, AM; Schittenhelm, M; Town, AR; Yee, KW | 1 |
| Chervontseva, AM; Romanov, IuA; Savchenko, VG | 1 |
| Berg, SL; Blaney, SM; Bomgaars, L; Dahl, G; Franklin, J; Geyer, JR; Klenke, R; Park, J; Winick, NJ | 1 |
| Burnett, AK; Milligan, DW; Wheatley, K | 1 |
| Beran, M; Bonate, P; Cortes, J; Du, M; Estey, E; Estrov, Z; Faderl, S; Ferrajoli, A; Gandhi, V; Garcia-Manero, G; Giles, FJ; Kantarjian, H; Keating, M; Kwari, M; O'Brien, S; Plunkett, W; Wierda, W | 1 |
| Ikarashi, Y; Imai, C; Kakihara, T; Tanaka, A; Uchiyama, M; Watanabe, A | 1 |
| Broekhuizen, AJ; Creutzig, U; Gibson, B; Hubeek, I; Kaspers, GJ; Peters, GJ; Schouten van Meeteren, AY; Talianidis, I; van Wering, ER | 1 |
| Bergman, AM; Hendriks, HR; Kuiper, CM; Myhren, F; Peters, GJ; Sandvold, ML | 1 |
| Horio, T; Kaminishi, Y; Katsuma, S; Nakagawa, S; Ohgi, T; Takagaki, K; Tanaka, T; Yano, J | 1 |
| Bauer, KS; Garimella, TS; Karp, JE; Ross, DD; Tan, M; Wu, S | 1 |
| Meng, XL | 1 |
| Aksu, S; Güven, GS; Koçak, T; Ozçakar, L | 1 |
| Billi, AM; Bortul, R; Cappellini, A; Conte, R; Grafone, T; Mantovani, I; Martelli, AM; Martinelli, G; Tabellini, G; Tazzari, PL | 1 |
| Ueda, T; Yamauchi, T | 1 |
| Pavlidis, N; Pentheroudakis, G | 1 |
| Abella, E; Brunet, S; del Potro, E; Esteve, J; Oriol, A; Ribera, JM | 1 |
| Fu, L; Kogoshi, H; Koyama, T; Nara, N; Tohda, S | 1 |
| Amadori, S; Beksac, M; Cermak, J; de Witte, T; Fenaux, P; Harousseau, J; Loeffler-Ragg, J; Neuwirtova, R; Nuessler, V; Solbu, G; Suciu, S; Willemze, R; Zwierzina, H | 1 |
| Barbier, M; Bignon, J; Boutonnat, J; Colle, PE; Faussat, AM; Marie, JP; Ronot, X; Thierry, J; Wdzieczak-Bakala, J | 1 |
| Giles, FJ; Huang, P; Keating, MJ; Pelicano, H; Xu, RH; Zhang, H | 1 |
| Albitar, M; Cahill, A; Cortes, J; Faderl, S; Ferrajoli, A; Garcia-Manero, G; Gerson, S; Giles, F; Jabbour, E; Kantarjian, H; Karsten, V; Kornblau, S; O'Brien, S; Ravandi, F; Sznol, M; Thomas, D; Verstovsek, S; Yee, K | 1 |
| Alakavuklar, M; Firat, D; Kansu, E; Kars, A; Koc, Y; Tekuzman, G | 1 |
| Broekhuizen, R; Creutzig, U; den Boer, ML; Gibson, BE; Hubeek, I; Janka-Schaub, GE; Kaaijk, P; Kaspers, GJ; Peters, GJ; Pieters, R; van Wering, ES; Zwaan, CM | 1 |
| Asakura, H; Endo, T; Kami, M; Kim, SW; Kumano, K; Minauchi, K; Mori, S; Nakao, S; Nishio, M; Okumura, H; Ozaki, J; Shimadoi, S; Sugimori, N; Takami, A; Takaue, Y; Takemoto, Y; Yamazaki, H | 1 |
| Akutsu, M; Furukawa, Y; Izumi, T; Kano, Y; Kobayashi, H; Mano, H; Tsunoda, S | 1 |
| Cleverley, J | 1 |
| Aoun, M; Beguin, H; Georgala, A; Husson, M; Meuleman, N; Nolard, N; Vekemans, M | 1 |
| Duan, LN; Guo, ZK; Ji, SQ; Wang, HX | 1 |
| Braeckman, R; Chamberlain, M; Maria, B; Phuphanich, S | 1 |
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| Hara, M; Kimura, I; Kitazima, K; Takahashi, I; Tokuda, M; Yorimitsu, S | 1 |
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| Gerasimova, GK; Golenko, OD; Maiakova, SA; Sidorova, TA; Volkova, MA | 1 |
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| Chen, SC; Chu, JY; Demello, D; Gale, GB; O'Connor, DM | 1 |
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| Azarnia, N; Brennan, J; Browman, G; Chervenick, P; Goldberg, J; Grunwald, H; Miller, K; Preisler, HD; Raza, A; Vogler, R | 1 |
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| Preisler, HD; Raza, A | 3 |
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| Abramson, N; Jones, GT | 1 |
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| Aoyagi, A; Fujiwara, M; Fuse, I; Hanano, M; Hattori, A; Hirosawa, H; Kashimura, M; Kishi, K; Koike, T; Koyama, S; Miura, R; Moriyama, Y; Nagayama, R; Ohnishi, M; Sakai, C; Sanada, M; Shibata, A; Shinada, S; Takahashi, M; Takai, K; Urushiyama, M | 1 |
| Arlin, ZA; Clarkson, BD; Dellaquila, C; Flomenberg, N; Gee, TS; Kempin, SJ; Mertelsmann, R; Straus, DJ; Young, CW | 1 |
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| Geissler, M; Jain, NC; Weller, RE | 1 |
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| Barlogie, B; Chubb, S; Plunkett, W | 1 |
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| Hirano, M; Ino, T; Matsui, T; Morishita, Y; Nakamura, K; Ono, Y; Saito, M; Shigemura, H; Shimizu, S | 1 |
| Fülle, HH; Koeppen, KM; Rühl, H; Schwerdtfeger, R | 1 |
| Jones, SP; Paterson, AR; Sawyer, WH; Wiley, JS | 1 |
| Early, AP; Preisler, HD; Rustum, YM; Slocum, H | 1 |
| Boiron, M; Gisselbrecht, C; Jacquillat, C; Marty, M; Weil, M | 1 |
| Hasegawa, K; Hida, K; Kano, Y; Kasahara, T; Okamura, J; Sakamoto, S; Sasaki, H; Takaku, F; Tsukada, T | 1 |
| Beswick, W; Chesterman, CN; Firkin, FC; Garson, OM; Januszewicz, E; Keating, MJ; Penington, DG | 1 |
| Doi, S; Ha, K; Ikeda, T; Tawa, A; Yabuuchi, H; Yumura, K | 1 |
| Adachi, T; Endo, Y; Fujimoto, S; Hara, M; Kimura, I; Kitajima, K; Kohi, F; Lai, M; Oda, Y; Ohmoto, E; Sanada, H; Takahashi, I; Takaoka, K; Tokioka, M; Uchida, K; Watanabe, S; Yorimitsu, S | 1 |
| Bennett, JM; Bertino, JR; Carbone, PP; Costello, W; Marsh, JC; Oken, MM; Skeel, RT; Tobin, MS | 1 |
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| Ganeshaguru, K; Hoffbrand, AV; Tattersall, MH | 1 |
| Krieger, O; Lutz, D; Nowotny, H; Waldner, R | 1 |
| Avilés-Miranda, A; Conte-Lanza, G; Monroy-Arellano, LM; Morales-Polanco, MR; Pizzuto-Chávez, J | 1 |
| Malarme, M; Stryckmans, PA | 1 |
| Cheever, MA; Farewell, VT; Fefer, A; Glucksberg, H; Sale, GE; Thomas, ED | 1 |
| David, R; Duhamel, G; Gorin, NC; Najman, A; Parlier, Y; Petit, JC; Salmon, C; Stachowiak, J | 1 |
| Moloney, WC; Rosenthal, DS | 1 |
| Kondrat'eva, NA; Kovaleva, LG; Kruglova, GV; Makhonova, LA; Volkova, MA | 1 |
| Shibata, A; Takahashi, M | 1 |
| Ohno, R; Yamada, K | 1 |
| Chang, LJ; Izaguirre, CA; McCulloch, EA; Smith, LJ | 1 |
| Goldberg, J; Gottlieb, AJ; Kirshner, JJ; Nelson, DA | 1 |
| Wiernik, PH | 3 |
| Bodey, GP; Bolivar, R; Fainstein, V | 1 |
| Kimura, K | 2 |
| Andreeff, M; Büchner, T; Clarkson, BD; Hiddemann, W; Melamed, MR | 1 |
| Bottomley, SS; Hussein, KK; Livingston, RB; Salem, Z | 1 |
| Andreeff, M; Büchner, T; Clarkson, BD; Hiddemann, W; Melamed, MR; Wörmann, B | 1 |
| Abe, I; Hori, K; Saito, S; Sato, H; Suzuki, M | 1 |
| Amare, M; Goodwin, JW; Maloney, TR; Morrison, FS; Park, CH | 1 |
| Appelbaum, FR; Cheever, MA; Fefer, A; Greenberg, PD; Kaplan, HG; Wood, T | 1 |
| Bodey, GP; Freireich, EJ; Gehan, EA; Keating, MJ; McCredie, KB; Smith, TL | 1 |
| Freireich, EJ; Gehan, EA; Keating, MJ; Smith, TL | 1 |
| Moffatt, JG; Okabayashi, T | 1 |
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| Breithaupt, H; Eckhardt, T; Löffler, H; Pralle, H; Schick, J; von Hattingberg, M | 1 |
| Berliner, S; Gallant, LA; Garfinkel, D; Pinkhas, J; Rothenberg, M; Shaklai, M; Shoenfeld, Y | 1 |
| Clarkson, BD; Gee, TS; Mertelsmann, R; Miké, V; Passe, S | 1 |
| Armitage, JO; Aunan, SB; Burns, CP; Dick, FR; Slymen, DJ | 1 |
| Ascari, E; Berzuini, C; Cresci, R; Mazzini, G; Montecucco, C; Riccardi, A; Traversi, E | 1 |
| Killmann, SA; Wantzin, GL | 1 |
| Burke, PJ; Karp, JE; Sanford, PL; Vaughan, WP | 1 |
| Danks, MK | 1 |
| Bakshi, D; Buscaglia, D; Early, AP; Kelly, E; Preisler, H; Rustum, YM; Slocum, HK; Wang, G; Wrzosek, C | 1 |
| Amare, M; Morrison, FS; Oishi, N; Pendleton, O; Saiki, JH; Schreiter, SL; Stuckey, WJ; Vial, R | 1 |
| Amare, M; Balcerzak, S; Benjamin, R; Costanzi, JJ; Hussein, K; Morrison, FS; Pendleton, OJ; Ryan, DH | 1 |
| Abe, M; Aiba, K; Chinen, T; Ezaki, K; Horikoshi, N; Ichiba, K; Inagaki, J; Inoue, K; Kobayashi, T; Kuraishi, Y; Meguro, S; Nagata, T; Ogawa, M | 1 |
| Andersson, B; Björkholm, M; Engstedt, L; Gahrton, G; Hast, R; Holm, G; Killander, A; Lantz, B; Lockner, D; Lönnqvist, B; Mellstedt, H; Oberg, G; Palmblad, J; Paul, C; Peterson, C; Simonsson, B; Stalfelt, AM; Udén, AM; Wadman, B | 1 |
| Dekker, AW; Punt, K; Sixma, JJ | 1 |
| Fujiwara, M; Hirosawa, H; Kishi, K; Koyama, S; Moriyama, Y; Sakai, C; Sanada, M; Shibata, A; Takahashi, M; Takai, K; Urushiyama, M | 1 |
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| Bateman, JR; Lewis, JP; Linman, JW; Pajak, TF | 1 |
| Cassileth, PA; Kahn, SB; Silber, R; Weiler, C | 1 |
| Drenthe-Schonk, A; Haanen, C; Linssen, P; Wessels, H | 1 |
| Early, AP; Gottlieb, AJ; Lanchant, NA; Preisler, HD | 1 |
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| Bloomfield, CD; Hasbrouck, DJ; Hurd, DD; Peterson, BA | 1 |
| Breithaupt, H; Schick, J | 1 |
| Fishman, DJ; Herzig, GP; Herzig, RH; Lazarus, HM; Phillips, GL; Roessmann, U | 1 |
| Oguro, M; Sueyama, H; Takagi, T | 1 |
| Maekawa, T; Omine, M; Tsuchiya, J | 1 |
| Kato, Y; Suzuki, H; Yamada, K | 1 |
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| Fujii, S; Hiroshige, Y; Ishida, Y; Kaku, K; Matsumoto, N; Miwa, S; Nakashima, K; Shinohara, K; Yaga, K | 1 |
| Brennan, DC; Lewis, JP | 1 |
| Amare, M; Goodwin, JW; Hoogstraten, B; Newcomb, MM; Park, CH; Savin, MA | 1 |
| Ezaki, K; Kato, Y; Kawashima, K; Kobayashi, M; Kodera, Y; Minami, S; Morishima, Y; Morishita, T; Nishiwaki, H; Ogura, M; Ohara, K; Ohno, R; Suzuki, H; Takeyama, H; Tanimoto, M; Watanabe, E; Yamada, H; Yamada, K; Yamaguchi, H; Yokomaku, S; Yoshikawa, S | 1 |
| Bremer, AM; Hayakawa, T; Mogami, H; Ushio, Y; West, CR; Yamada, K | 1 |
| Bloomfield, CD; Bosl, GJ; Gibbs, G; Malloy, M; Peterson, BA | 1 |
| Matthews, JH; Wood, JK | 1 |
| Hattori, KI; Kobayashi, S; Mitamura, E; Nakamura, S; Ohtake, S; Tanimoto, K; Yoshida, T | 1 |
| Barlogie, B; Keating, M; Latreille, J; McCredie, K; Plunkett, W; Raber, M | 1 |
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| Abe, T; Fujii, H; Kuzuyama, Y; Nakagawa, H; Sakabe, H; Sonoda, Y | 1 |
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| Oehme, J; Reckelkamm, E | 1 |
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| Frei, E; Gottlieb, JA; Gutterman, JU; McCredie, KB; Rodriguez, V | 1 |
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107 review(s) available for cytarabine and Leukemia
| Article | Year |
|---|---|
Influencing Factors and Coping Strategies of Hospitalization in Children with Leukemia Complicated with Pneumonia.
Topics: Adaptation, Psychological; Child; Cytarabine; Hospitalization; Humans; Leukemia; Pneumonia; Retrospective Studies | 2022 |
The FLAMSA concept-past and future.
Topics: Amsacrine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Forecasting; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Immunotherapy, Adoptive; Leukemia; Transplantation Conditioning; Transplantation, Homologous; Vidarabine | 2020 |
Myeloprotection by cytidine deaminase gene transfer in antileukemic therapy.
Topics: Animals; Antineoplastic Agents; Cytarabine; Cytidine Deaminase; Drug Resistance, Neoplasm; Gene Expression; Gene Transfer Techniques; Genetic Therapy; Hematopoietic Stem Cells; Humans; Leukemia; Mice; Myelopoiesis | 2013 |
High-dose cytarabine (HD araC) in the treatment of leukemias: a review.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Consolidation Chemotherapy; Cytarabine; Drug Administration Schedule; Humans; Induction Chemotherapy; Leukemia | 2013 |
Cutaneous manifestations in leukemia patients.
Topics: Adenine Nucleotides; Antineoplastic Agents; Arabinonucleosides; Clofarabine; Cytarabine; Dermatomycoses; Etoposide; Humans; Leukemia; Mastocytosis; Niacinamide; Paraneoplastic Syndromes; Phenylurea Compounds; Skin Diseases, Bacterial; Skin Neoplasms; Sorafenib | 2016 |
Intrathecal liposomal cytarabine: more friend than foe?
Topics: Antimetabolites, Antineoplastic; Cytarabine; Drug Carriers; Humans; Injections, Spinal; Leukemia; Liposomes; Treatment Outcome | 2008 |
Treatment of lymphomatous and leukemic meningitis with liposomal encapsulated cytarabine.
Topics: Antimetabolites, Antineoplastic; Capsules; Clinical Trials as Topic; Cytarabine; Humans; Injections, Spinal; Leukemia; Liposomes; Lymphoma; Meningitis; Treatment Outcome | 2008 |
Intrathecal liposomal cytarabine in relapsed or refractory infant and pediatric leukemias: the Children's Hospital of Philadelphia experience and review of the literature.
Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Child, Preschool; Cytarabine; Drug Resistance, Neoplasm; Female; Humans; Infant; Injections, Spinal; Leukemia; Liposomes; Male; Philadelphia; Recurrence | 2010 |
Development of cytarabine prodrugs and delivery systems for leukemia treatment.
Topics: Antineoplastic Agents; Cytarabine; Drug Delivery Systems; Humans; Leukemia; Lymphoma, Non-Hodgkin; Prodrugs | 2010 |
Clofarabine in leukemia.
Topics: Adenine Nucleotides; Antineoplastic Agents; Arabinonucleosides; Clinical Trials as Topic; Clofarabine; Cytarabine; Drug Therapy, Combination; Humans; Leukemia; Lymphoproliferative Disorders | 2010 |
[Significance of intensified conditioning regimen for allogeneic hematopoietic stem cell transplantation for treatment of acute leukemias].
Topics: Acute Disease; Cyclophosphamide; Cytarabine; Etoposide; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Melphalan; Recurrence; Risk; Transplantation Conditioning; Transplantation, Homologous; Whole-Body Irradiation | 2011 |
Troxacitabine-based therapy of refractory leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Cytarabine; Cytosine; Dioxolanes; Humans; Idarubicin; Leukemia; Remission Induction; Topotecan | 2002 |
Imatinib mesylate selectively influences the cellular metabolism of cytarabine in BCR/ABL negative leukemia cell lines and normal CD34+ progenitor cells.
Topics: Antigens, CD; Antigens, CD34; Benzamides; Bone Marrow Cells; Cell Line, Tumor; Cytarabine; Gene Deletion; Genes, abl; Humans; Imatinib Mesylate; Leukemia; Piperazines; Pyrimidines | 2004 |
Management of leptomeningeal malignancy.
Topics: Adenocarcinoma; Algorithms; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Arachnoid Cysts; Carcinoma; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Delayed-Action Preparations; Enzyme Inhibitors; Humans; Injections, Intravenous; Injections, Spinal; Leukemia; Lymphoma; Meningeal Neoplasms; Methotrexate; Palliative Care; Randomized Controlled Trials as Topic; Thiotepa; Topoisomerase I Inhibitors; Topotecan | 2005 |
[Strategy for chemical biology using affinity magnetic nanobeads].
Topics: Affinity Labels; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Deoxycytidine Kinase; Drug Evaluation, Preclinical; Humans; Leukemia; Methotrexate; Microspheres; Mitochondria; Nanoparticles; Polymethacrylic Acids; Porphyrins; Proteins | 2007 |
Liposomal cytarabine for leukemic and lymphomatous meningitis: recent developments.
Topics: Animals; Cytarabine; Humans; Leukemia; Liposomes; Lymphoma; Meningitis; Randomized Controlled Trials as Topic | 2008 |
Therapy in childhood acute nonlymphocytic leukemia (ANLL). Evolution of current concepts of chemotherapy.
Topics: Acute Disease; Adolescent; Adult; Asparaginase; Azauridine; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia; Prednisone; Thioguanine; Thioinosine; Vincristine | 1981 |
[Chemotherapy of the malignancies from the viewpoint of pharmacology and biochemistry of cytosine arabinoside (ara-C) and its derivatives].
Topics: Ancitabine; Cytarabine; Humans; Kinetics; Leukemia | 1982 |
Methods for evaluating response to treatment in adult acute leukemia.
Topics: Acute Disease; Adult; Aging; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Clinical Trials as Topic; Cytarabine; Doxorubicin; Drug Therapy, Combination; Glycopeptides; Humans; Leukemia; Models, Biological; Peptide Fragments; Prednisone; Pro-Opiomelanocortin; Prognosis; Prospective Studies; Regression Analysis; Vincristine | 1983 |
Adult acute nonlymphocytic leukemia.
Topics: Acute Disease; Adult; Aged; Antigens, Neoplasm; Antigens, Surface; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cytarabine; Daunorubicin; Humans; Leukemia; Meningeal Neoplasms; Methotrexate; Middle Aged; Thioguanine | 1984 |
[Symposium on treatment of cancer. 1. Chemotherapy of acute leukemia in adults].
Topics: Aclarubicin; Acute Disease; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Clinical Trials as Topic; Cytarabine; Doxorubicin; Humans; Interferon Type I; Leukemia; Middle Aged; Naphthacenes | 1984 |
[Chemotherapy of acute leukemia].
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; DNA, Neoplasm; Drug Administration Schedule; Drug Tolerance; Female; Humans; Leukemia; Male; Middle Aged | 1984 |
[Neurological problems in malignant hemopathies in children. II. Neurotoxicity of antiblastic drugs and radiotherapy].
Topics: Antineoplastic Agents; Asparaginase; Central Nervous System Diseases; Child; Child, Preschool; Cytarabine; Humans; Infant; Leukemia; Lymphoma; Methotrexate; Radiotherapy; Vincristine | 1982 |
Is there a role for thymidine in cancer chemotherapy?
Topics: Cytarabine; Drug Therapy, Combination; Fluorouracil; Humans; Kinetics; Leukemia; Methotrexate; Neoplasms; Thymidine | 1982 |
Adult acute nonlymphocytic leukemias.
Topics: Acute Disease; Aged; Anemia; Anemia, Aplastic; Anemia, Sideroblastic; Blood Transfusion; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Drug Resistance; Female; Hemorrhage; Humans; Immunotherapy; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Platelet Transfusion; Spinal Cord; Syndrome | 1980 |
Deoxyribonucleoside triphosphate pools in human bone marrow and leukaemic cells.
Topics: Bone Marrow; Cells, Cultured; Cytarabine; Deoxyribonucleosides; DNA; Humans; Leukemia; Myeloproliferative Disorders; Phytohemagglutinins; Time Factors | 1980 |
[The clinical significance of the Philadelphia chromosome in acute leukaemia (author's transl)].
Topics: Acute Disease; Adult; Blood Transfusion; Chromosomes, Human, 21-22 and Y; Cytarabine; Female; Glucocorticoids; Hematopoietic Stem Cells; Humans; Leukapheresis; Leukemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Vincristine | 1980 |
[Prophylactic treatment of meningeal leukemia (author's transl)].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Antineoplastic Agents; Child; Cytarabine; Female; Humans; Injections, Spinal; Leukemia; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Nitrosourea Compounds; Radiation Injuries; Radiotherapy Dosage | 1981 |
[In-vitro prediction of clinical response to chemotherapy in leukemia].
Topics: Cell Division; Colony-Forming Units Assay; Cytarabine; Daunorubicin; Humans; In Vitro Techniques; Leukemia; Mitotic Index | 1981 |
Renewal and determination in leukemic blast populations.
Topics: Antibodies, Monoclonal; Cell Differentiation; Cell Division; Cells, Cultured; Cytarabine; Doxorubicin; Genes; Granulocytes; Hematopoietic Stem Cells; Humans; Leukemia; Leukemia, Myeloid, Acute; Models, Biological; Phytohemagglutinins; Transfection | 1982 |
Infectious complications in leukemic patients.
Topics: Acute Disease; Aminoglycosides; Anti-Bacterial Agents; Antibody Formation; Bacterial Infections; Clostridium Infections; Corynebacterium Infections; Cytarabine; Drug Synergism; Hepatitis A; Hepatitis B; Herpes Zoster; Humans; Immunity, Cellular; Legionnaires' Disease; Leukemia; Methicillin; Mycoses; Pseudomonas Infections; Staphylococcal Infections | 1982 |
Overview of progress in hematology in 1981 with special reference to leukocyte.
Topics: Aclarubicin; Acute Disease; Adult; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Cells, Cultured; Child; Cytarabine; Deoxycytidine Monophosphate; Drug Therapy, Combination; Humans; Kinetics; Leukemia; Leukemia L1210; Leukocytes; Naphthacenes | 1982 |
Evolution of the arabinosides and the pharmacology of fludarabine.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biological Availability; Cytarabine; Humans; Leukemia; Vidarabine | 1994 |
Assay of cell resistance to ara-C.
Topics: Adult; Aged; Bromodeoxyuridine; Cell Separation; Cytarabine; DNA, Neoplasm; Drug Resistance; Flow Cytometry; Humans; In Vitro Techniques; Leukemia; Middle Aged; Staining and Labeling; Tumor Cells, Cultured | 1994 |
Modulation of arabinosylcytosine metabolism during leukemia therapy.
Topics: Antineoplastic Agents; Arabinofuranosylcytosine Triphosphate; Biotransformation; Cytarabine; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia; Vidarabine | 1994 |
Adult leukaemia in 1995: new directions.
Topics: Adult; Aged; Bone Marrow Transplantation; Child; Chromosomes, Human, Pair 22; Chromosomes, Human, Pair 9; Cytarabine; Humans; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Promyelocytic, Acute; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Translocation, Genetic; Tretinoin | 1995 |
[State of the art of chemotherapy for adult acute leukemia in Japan].
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Humans; Japan; Leukemia; Mercaptopurine; Middle Aged; Multicenter Studies as Topic; Prednisolone; Remission Induction; Survival Rate | 1993 |
Intravenous mercaptopurine: life begins at 40.
Topics: Acute Disease; Animals; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Infusions, Intravenous; Leukemia; Mercaptopurine; Methotrexate | 1993 |
Growth factors in the management of adult acute leukemia.
Topics: Acute Disease; Adjuvants, Immunologic; Adult; Aged; Antineoplastic Agents; Bone Marrow Diseases; Cell Differentiation; Clinical Trials as Topic; Cytarabine; Drug Evaluation; Growth Substances; Hematopoietic Cell Growth Factors; Hematopoietic Stem Cells; Humans; Immunologic Factors; Leukemia; Middle Aged | 1993 |
Cellular pharmacodynamics of anticancer drugs.
Topics: Cytarabine; DNA, Neoplasm; Humans; Leukemia | 1993 |
Biochemical modulation of arabinosylcytosine for therapy of leukemias.
Topics: Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Cytarabine; Humans; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Vidarabine | 1993 |
Intracellular pharmacodynamics in leukemia therapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Cytarabine; Humans; Leukemia; Mitoxantrone; Vidarabine | 1996 |
Treatment of adult acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Clinical Trials as Topic; Combined Modality Therapy; Cytarabine; Hematopoietic Cell Growth Factors; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Mice; Middle Aged; Multicenter Studies as Topic; Remission Induction; Risk Factors; Survival Analysis | 1997 |
[Update on malignant hematologic diseases].
Topics: Antineoplastic Agents; Cytarabine; Humans; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Multiple Myeloma | 1998 |
The management of neoplastic disorders of haematopoiesis in children with Down's syndrome.
Topics: Acute Disease; Adolescent; Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cytarabine; Daunorubicin; Disease-Free Survival; Down Syndrome; Female; Genetic Predisposition to Disease; Humans; Infant; Infant, Newborn; Leukemia; Leukemia, Myeloid; Male; Maternal Age; Myeloproliferative Disorders; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Vincristine | 2000 |
The role of purine analogue combinations in the management of acute leukemias.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Synergism; Humans; Leukemia; Purines | 2001 |
[Intrathecal application of antineoplastic agents (author's transl)].
Topics: Aminopterin; Antineoplastic Agents; Asparaginase; Azaguanine; Brain Neoplasms; Cyclophosphamide; Cytarabine; Encephalitis; Folic Acid Antagonists; Gold Radioisotopes; Humans; Injections, Spinal; Kinetics; Leukemia; Lumbar Vertebrae; Methotrexate; Thiotepa; Vinca Alkaloids | 1978 |
The mechanisms of lethal action of arabinosyl cytosine (araC) and arabinosyl adenine (araA).
Topics: Adenine; Adenosine Deaminase Inhibitors; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Azepines; Cell Division; Cell Survival; Cells, Cultured; Cytarabine; Cytidine Deaminase; Cytosine Nucleotides; Deoxyribonucleosides; DNA; Humans; Inosine Nucleotides; Leukemia; Tetrahydrouridine; Vidarabine; Virus Diseases | 1977 |
Metabolism of 1-beta-D-arabinofuranosylcytosine in human leukemic cells.
Topics: Bone Marrow; Cytarabine; DNA, Neoplasm; Drug Therapy, Combination; Female; Humans; In Vitro Techniques; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Male; RNA, Neoplasm; Tetrahydrouridine; Thymidine | 1977 |
Current concepts of leukemia and results of recent treatment programs.
Topics: Cell Transformation, Neoplastic; Clone Cells; Cytarabine; Hematopoiesis; Hematopoietic Stem Cells; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute | 1978 |
Approaches to the treatment of acute leukemia and lymphoma in adults.
Topics: Acute Disease; Adult; Animals; BCG Vaccine; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Environment, Controlled; Humans; Immunotherapy; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma; Mice; Prednisone; Vincristine | 1978 |
[Research results and prospects in the field of experimental leukemia chemotherapy].
Topics: Alkylating Agents; Amino Acids; Antibiotics, Antineoplastic; Antineoplastic Agents; Cytarabine; Drug Therapy, Combination; Humans; Leukemia; Nitrosourea Compounds; Pyrimidine Nucleosides; Research; Structure-Activity Relationship; USSR | 1979 |
Treatment of overt CNS leukemia.
Topics: Adrenal Cortex Hormones; Aminopterin; Antineoplastic Agents; Asparaginase; Blood-Brain Barrier; Carmustine; Child; Cytarabine; Drug Therapy, Combination; Humans; Injections, Spinal; Leukemia; Meningeal Neoplasms; Methotrexate; Pyrimethamine | 1979 |
Drug resistance in leukemia.
Topics: Alkylating Agents; Antimetabolites; Antineoplastic Agents; Cytarabine; Dactinomycin; Daunorubicin; Doxorubicin; Drug Resistance; Drug Therapy, Combination; Leukemia; Methotrexate; Prednisone; Purines; Pyrimidines; Vinblastine; Vincristine | 1975 |
Management of acute leukemia in adults.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Blood Transfusion; Cytarabine; Daunorubicin; Drug Therapy, Combination; Hematopoietic Stem Cells; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Middle Aged; Prognosis; Remission, Spontaneous; Thioguanine; Thrombocytopenia; Time Factors | 1975 |
Early consolidation chemotherapy for adults with acute leukemia in remission.
Topics: Acute Disease; Adolescent; Adult; Anti-Bacterial Agents; Antineoplastic Agents; Bacterial Infections; Cytarabine; Enterocolitis, Pseudomembranous; Female; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Necrosis; Prednisone; Remission, Spontaneous; Vincristine | 1976 |
Conditioning regimens for allogeneic bone marrow transplantation.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Purging; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Cytarabine; Etoposide; Humans; Leukemia; Lymphocyte Depletion; Melphalan; T-Lymphocytes; Transplantation, Homologous; Whole-Body Irradiation | 1992 |
Current pharmacological treatment approaches to central nervous system leukaemia.
Topics: Adolescent; Adult; Antineoplastic Agents; Central Nervous System Diseases; Child; Child, Preschool; Cytarabine; Drug Evaluation; Humans; Infant; Infant, Newborn; Leukemia; Meningeal Neoplasms; Methotrexate | 1991 |
Effect of dose on the pharmacokinetic and pharmacodynamic effects of cytarabine.
Topics: Animals; Cytarabine; DNA, Neoplasm; Dose-Response Relationship, Drug; Humans; Leukemia; Remission Induction | 1991 |
Antimetabolites.
Topics: Antimetabolites, Antineoplastic; Cytarabine; Humans; Leukemia; Purines | 1991 |
Idarubicin: a second-generation anthracycline.
Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Drug Evaluation; Humans; Idarubicin; Leukemia; Neoplasms; Remission Induction | 1991 |
Leukemia: experimental and preclinical studies.
Topics: Alkylating Agents; Animals; Antibiotics, Antineoplastic; Cell Line; Chromosome Aberrations; Cytarabine; Drug Resistance; Humans; Leukemia; Methotrexate; Prognosis | 1990 |
Pharmacologically directed design of leukemia therapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cytarabine; Drug Evaluation; Humans; Leukemia; Leukemia, Myeloid, Acute; Mitoxantrone | 1990 |
Differentiating agents in the treatment of leukemia.
Topics: Cell Differentiation; Cytarabine; Humans; Interferon Type I; Leukemia; Leukemia, Hairy Cell; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Myelodysplastic Syndromes; Tretinoin | 1990 |
Differentiating agents in the treatment of leukemia and myelodysplastic syndromes.
Topics: Cell Differentiation; Cell Division; Cytarabine; Humans; Interferon Type I; Leukemia; Leukemia, Hairy Cell; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Myelodysplastic Syndromes; Tretinoin | 1990 |
Nonhematologic toxicities of selected chemotherapeutic agents used in the treatment of adult leukemia.
Topics: Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia; Mitoxantrone; Nursing Assessment | 1990 |
Cell kinetics as related to treatment of patients with acute nonlymphoid leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bone Marrow; Bone Marrow Cells; Cell Cycle; Child; Cytarabine; Daunorubicin; Doxorubicin; Etoposide; Flow Cytometry; Hematopoietic Stem Cells; Humans; Hydrocortisone; Leukemia; Methotrexate; Mitotic Index; Neoplastic Stem Cells; Prednisone; Prognosis; Vincristine | 1985 |
Central nervous system pharmacology of antileukemic drugs.
Topics: Antineoplastic Agents; Central Nervous System; Child; Cytarabine; Humans; Leukemia; Mercaptopurine; Methotrexate; Thiotepa | 1989 |
[Use of recombinant hematopoietic growth factors after chemotherapy and high-dose chemo-radiotherapy].
Topics: Anemia, Aplastic; Antineoplastic Agents; Colony-Stimulating Factors; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Drug Evaluation; Etoposide; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Melphalan; Neoplasms; Radiotherapy | 1989 |
Etoposide: fifteen years experience.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Evaluation; Etoposide; Hodgkin Disease; Humans; Leukemia; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Lomustine; Melphalan; Mitoxantrone | 1989 |
Central nervous system leukemia.
Topics: Child; Clinical Trials as Topic; Combined Modality Therapy; Cytarabine; Humans; Leukemia; Meningeal Neoplasms; Methotrexate; Radiotherapy Dosage | 1988 |
New strategies in the management of acute leukemias.
Topics: Acute Disease; Amsacrine; Aneuploidy; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Drug Evaluation; Humans; Leukemia; Leukemia, Lymphoid; Myelodysplastic Syndromes; Prognosis; Remission Induction | 1987 |
Role of thymidine in biochemical modulation: a review.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Cytarabine; Deoxycytidine Kinase; DNA Replication; DNA, Neoplasm; Drug Evaluation; Drug Synergism; Fluorouracil; Folic Acid Antagonists; Humans; Interphase; Kinetics; Leukemia; Methotrexate; Mice; Neoplasms; Neoplasms, Experimental; Nucleic Acid Synthesis Inhibitors; Nucleotides; Phosphonoacetic Acid; RNA, Neoplasm; Species Specificity; Thymidine | 1987 |
Current status of treatment of acute leukemia in adults: an overview of the Memorial experience and review of literature.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Examination; Cytarabine; Female; Humans; Leukemia; Leukemia, Lymphoid; Male; Middle Aged; Prognosis; Recurrence; Thioguanine; Time Factors | 1986 |
Overview of the clinical relevance of autologous bone marrow transplantation.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmustine; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Drug Evaluation; Drug Resistance; Etoposide; Hodgkin Disease; Humans; Leukemia; Leukemia, Lymphoid; Lymphoma; Melphalan; Neoplasm Recurrence, Local; Neoplasms; Thioguanine; Transplantation, Autologous | 1986 |
[Cell differentiation induction therapy in leukemia].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Cell Differentiation; Cell Division; Cell Line; Cytarabine; Humans; Leukemia; Leukemia, Experimental; Tretinoin | 1986 |
Differentiation factors.
Topics: Acetamides; Antineoplastic Agents; Calcitriol; Cell Differentiation; Colony-Stimulating Factors; Cytarabine; Humans; Leukemia; Lymphokines; Retinoids; Tetradecanoylphorbol Acetate | 1986 |
Indications for and benefits of intensive therapies in treatment of childhood cancers.
Topics: Acute Disease; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Etoposide; Humans; Leukemia; Leukemia, Lymphoid; Lymphoma; Melphalan; Methotrexate; Neoplasms; Osteosarcoma; Risk; Sarcoma, Ewing | 1986 |
A critical appraisal of low-dose cytosine arabinoside in patients with acute non-lymphocytic leukemia and myelodysplastic syndromes.
Topics: Acute Disease; Adolescent; Adult; Aged; Bone Marrow; Child; Cytarabine; Follow-Up Studies; Humans; Leukemia; Leukocyte Count; Middle Aged; Myelodysplastic Syndromes; Platelet Count | 1986 |
Leukemic cell maturation.
Topics: Cell Differentiation; Cell Line; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Dimethyl Sulfoxide; Genotype; Hematopoietic Stem Cells; Humans; Leukemia; Leukemia, Myeloid, Acute; Neoplastic Stem Cells; Neutrophils; Oncogenes; Phenotype; Tetradecanoylphorbol Acetate; Vitamin A | 1985 |
Acute nonlymphocytic leukemia.
Topics: Adolescent; Adult; Antigens, Surface; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Chromosome Aberrations; Cytarabine; Doxorubicin; Hematopoietic Stem Cells; Humans; Leukemia; Leukemia, Myeloid, Acute; Nervous System Neoplasms; Prednisolone; Prognosis; Recurrence; Risk; Vincristine | 1985 |
Sequential high-dose ara-C and asparaginase in the therapy of previously treated and untreated patients with acute leukemia.
Topics: Aging; Animals; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Asparaginase; Child; Clinical Trials as Topic; Cytarabine; Daunorubicin; DNA; Dose-Response Relationship, Drug; Drug Resistance; Humans; Kinetics; Leukemia; Leukemia, Lymphoid; Middle Aged; Time Factors | 1985 |
Studies on the cytotoxicity of cytosine arabinoside.
Topics: Adolescent; Adult; Arabinofuranosylcytosine Triphosphate; Bone Marrow; Cell Cycle; Cell Differentiation; Cells, Cultured; Clone Cells; Colony-Forming Units Assay; Cytarabine; DNA; Drug Resistance; Female; Granulocytes; Half-Life; Humans; Interphase; Kinetics; Leukemia; Male; Middle Aged; Phosphorylation; Recurrence | 1985 |
Dose-related pharmacologic effects of high-dose ara-C and its self-potentiation.
Topics: Aging; Animals; Arabinofuranosyluracil; Biological Transport; Bone Marrow; Cell Line; Cell Membrane; Clinical Trials as Topic; Cytarabine; DNA; Dose-Response Relationship, Drug; Drug Resistance; Half-Life; Humans; Interphase; Leukemia; Leukemia L5178; Time Factors | 1985 |
Cytosine arabinoside in experimental combination therapy.
Topics: Aminoacridines; Amsacrine; Animals; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Cisplatin; Cyclophosphamide; Cytarabine; Daunorubicin; DNA; DNA Repair; Doxorubicin; Drug Interactions; Drug Resistance; Humans; Interphase; Leukemia; Mercaptopurine; Phosphorylation; Thioguanine; Thymidine; Time Factors | 1985 |
Cellular and clinical pharmacology of low-dose ara-C.
Topics: Adult; Aged; Aphidicolin; Bone Marrow; Cell Differentiation; Cell Division; Cell Line; Cytarabine; Diterpenes; DNA; DNA Replication; Dose-Response Relationship, Drug; Female; Hemoglobins; Humans; Karyotyping; Kinetics; Leukemia; Male; Middle Aged; Preleukemia | 1985 |
Acute leukemia in adults.
Topics: Adult; Alkaline Phosphatase; BCG Vaccine; Blood Transfusion; Bone Marrow Examination; Central Nervous System Diseases; Cytarabine; Daunorubicin; Diagnosis, Differential; Drug Combinations; Drug Therapy, Combination; Esterases; Humans; Immunotherapy; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphocyte Transfusion; Meningitis; Microscopy, Electron; Neutrophils; Staining and Labeling; Subarachnoid Hemorrhage; Thioguanine | 1974 |
Paraplegia following intrathecal chemotherapy.
Topics: Adolescent; Alcohols; Autopsy; Benzyl Compounds; Child; Child, Preschool; Cytarabine; Female; Humans; Injections, Spinal; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Male; Methotrexate; Parabens; Paraplegia; Pharmaceutic Aids; Spinal Nerve Roots; Time Factors | 1972 |
Passive immunization against varicella-zoster infections and other modes of therapy.
Topics: Adult; Blood Transfusion; Chickenpox; Child; Cross Infection; Cytarabine; Female; Herpes Zoster; Humans; Idoxuridine; Immune System Diseases; Immunity, Maternally-Acquired; Immunization; Immunoglobulins; Interferon Inducers; Leukemia; Pregnancy; Pregnancy Complications, Infectious; Steroids | 1973 |
The emergence of drug resistance in tumours: a characteristic which may be exploited therapeutically.
Topics: Aminohydrolases; Animals; Cytarabine; Cytidine; DNA; Drug Resistance; Humans; Leukemia; Leukemia L1210; Methotrexate; Neoplasms | 1973 |
[Treatment of acute leukemias].
Topics: Acute Disease; Adult; Age Factors; Antineoplastic Agents; Asparaginase; Child; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methods; Methotrexate; Prednisolone; Recurrence; Remission, Spontaneous; Vincristine | 1973 |
[Achievements in the treatment of leukemia and lymphoma].
Topics: Acute Disease; Animals; Antineoplastic Agents; Burkitt Lymphoma; Chemical Phenomena; Chemistry; Cytarabine; Drug Therapy, Combination; Humans; Immunotherapy; Leukemia; Lymphoma; Methods; Remission, Spontaneous; Time Factors | 1973 |
Present treatment of acute leukemias.
Topics: Asparaginase; Blood Transfusion; Cytarabine; Daunorubicin; Humans; Immunotherapy; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocytes; Meninges; Mercaptopurine; Methotrexate; Prednisone; Remission, Spontaneous | 1973 |
Predictive tests in cancer. Tuesday 9 April 1974.
Topics: Age Factors; Breast Neoplasms; Cell Movement; Clinical Enzyme Tests; Colonic Neoplasms; Cytarabine; Diagnosis, Differential; Doxorubicin; Drug Combinations; Drug Evaluation; Drug Evaluation, Preclinical; Fluorouracil; Humans; Kinetics; Leukemia; Mercaptopurine; Methods; Methotrexate; Models, Chemical; Neoplasms; Prognosis; Sarcoma; Testosterone; Thioguanine | 1974 |
[Current status of cytostatic therapy].
Topics: Adrenal Cortex Hormones; Alkylating Agents; Antibiotics, Antineoplastic; Antineoplastic Agents; Cytarabine; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Hodgkin Disease; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Mitosis; Neoplasm Metastasis; Thymine Nucleotides | 1974 |
Chemotherapy and the life cycle of leukaemic cells. A comparison between the growth characteristics of human acute leukaemia and the murine leukaemia L 1210.
Topics: Anilides; Animals; Cell Division; Cyclophosphamide; Cytarabine; DNA, Neoplasm; Fluorouracil; Humans; Hydroxyurea; In Vitro Techniques; Leukemia; Leukemia L1210; Leukemia, Lymphoid; Mechlorethamine; Mercaptopurine; Methotrexate; Mice; Mitosis; Nitroso Compounds; Prednisone; Thymidine; Time Factors; Tritium; Vinblastine; Vincristine | 1969 |
[Burkitt's lymphoma and acute leukemias].
Topics: Acute Disease; Animals; Asparaginase; Burkitt Lymphoma; Child; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Fluorouracil; Humans; Leukemia; Melphalan; Mercaptopurine; Methotrexate; Mice; Oncogenic Viruses; Prednisolone; Prednisone; Vincristine | 1969 |
Treatment of acute leukemia.
Topics: Adrenal Cortex Hormones; Age Factors; Anti-Bacterial Agents; Asparaginase; Blood Platelets; Blood Transfusion; Bone Marrow Cells; Cyclophosphamide; Cytarabine; Folic Acid Antagonists; Humans; Leukemia; Mercaptopurine; Metals; Methotrexate; Prognosis; Radioisotopes; Radiotherapy; Staphylococcal Infections; Steroids; Vincristine | 1969 |
[Cytostatic therapy of acute leukemia (review of the literature)].
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Asparaginase; Cyclophosphamide; Cytarabine; Drug Synergism; Humans; Hydroxyurea; Leukemia; Vinblastine; Vincristine | 1969 |
[Biochemistry of antileukemic drugs].
Topics: Adrenal Cortex Hormones; Alkylating Agents; Antineoplastic Agents; Asparaginase; Busulfan; Chlorambucil; Cyclophosphamide; Cytarabine; Daunorubicin; Leukemia; Mannomustine; Mercaptopurine; Methotrexate; Vincristine | 1970 |
[Nucleic acid metabolism of leukemia cell].
Topics: Busulfan; Cytarabine; Dexamethasone; DNA; DNA, Neoplasm; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukocytes; Mercaptopurine; Nucleic Acids; Prednisolone; Pyrimidines; RNA; RNA, Neoplasm | 1970 |
Kinetics of normal and leukemic leukocyte populations and relevance to chemotherapy.
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Bone Marrow Cells; Cell Division; Cytarabine; Hematopoietic System; Humans; Kinetics; Leukemia; Leukemia L1210; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Lymphocytes; Mice; Neoplasm Transplantation; Thymidine; Time Factors; Tritium | 1970 |
Changing concepts of treatment in acute leukemia.
Topics: Acute Disease; Animals; Antineoplastic Agents; Asparaginase; Cell Differentiation; Cell Division; Cytarabine; DNA; Erythropoiesis; Hematopoiesis; Humans; Immunosuppressive Agents; Kinetics; Leukemia; Leukemia, Experimental; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mice; Mitosis; Models, Biological; Oncogenic Viruses; Prednisone; Remission, Spontaneous; Time Factors | 1971 |
[Cytostatic chemotherapy of neoplasms in children].
Topics: Adrenal Cortex Hormones; Aminopterin; Antineoplastic Agents; Asparaginase; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Cytarabine; Daunorubicin; Fluorouracil; Humans; Leukemia; Lymphoma; Mercaptopurine; Methotrexate; Nitrogen Mustard Compounds; Procarbazine; Sarcoma; Vinblastine; Vincristine | 1971 |
[Antimetabolites].
Topics: Allopurinol; Animals; Antimetabolites; Azathioprine; Cell Division; Chemical Phenomena; Chemistry; Cytarabine; DNA, Neoplasm; Fluorouracil; Folic Acid Antagonists; Humans; Leukemia; Mercaptopurine; Methotrexate; Neoplasms; Pyrimidines; Thioguanine | 1971 |
[Competitive enzyme mechanisms in the therapy of hemoblastosis using antimetabolites].
Topics: Adult; Allopurinol; Amidohydrolases; Antimetabolites; Cytarabine; Enzyme Inhibitors; Female; Fluorouracil; Folic Acid Antagonists; Humans; Leukemia; Ligases; Male; Mercaptopurine; Middle Aged; Thymidine Kinase; Xanthine Oxidase | 1968 |
Multiple combination therapy in cancer chemotherapy in Japan.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Chloroquine; Cyclophosphamide; Cytarabine; Drug Synergism; Fluorouracil; Humans; Japan; Leukemia; Lymphoma; Mercaptopurine; Mitomycins; Neoplasms; Podophyllin; Prednisolone; Thiotepa; Vincristine; Vitamin K 1 | 1969 |
138 trial(s) available for cytarabine and Leukemia
| Article | Year |
|---|---|
FLA-IDA salvage chemotherapy combined with a seven-day course of venetoclax (FLAVIDA) in patients with relapsed/refractory acute leukaemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia; Male; Middle Aged; Recurrence; Salvage Therapy; Sulfonamides; Vidarabine | 2020 |
Outcome of relapse in children and adolescents with B-cell non-Hodgkin lymphoma and mature acute leukemia: A report from the French LMB study.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Carboplatin; Child; Child, Preschool; Cytarabine; Disease-Free Survival; Etoposide; Female; Follow-Up Studies; France; Humans; Ifosfamide; Infant; Leukemia; Lymphoma, Large B-Cell, Diffuse; Male; Prospective Studies; Recurrence; Rituximab; Survival Rate | 2019 |
Improved outcome of adult Burkitt lymphoma/leukemia with rituximab and chemotherapy: report of a large prospective multicenter trial.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Murine-Derived; Antigens, CD20; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Cyclophosphamide; Cytarabine; Disease-Free Survival; Etoposide; Female; Humans; Ifosfamide; Immunotherapy; Injections, Spinal; Leukemia; Male; Methotrexate; Middle Aged; Prognosis; Prospective Studies; Remission Induction; Rituximab; Young Adult | 2014 |
[IDA-FLAG regimen in treatment of patients with refractory or relapsed acute leukemia].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Vidarabine | 2009 |
Phase 1 and pharmacokinetic study of bolus-infusion flavopiridol followed by cytosine arabinoside and mitoxantrone for acute leukemias.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Flavonoids; Humans; Infusion Pumps; Leukemia; Male; Middle Aged; Mitoxantrone; Piperidines; Young Adult | 2011 |
Phase I pharmacokinetic and pharmacodynamic study of the multikinase inhibitor sorafenib in combination with clofarabine and cytarabine in pediatric relapsed/refractory leukemia.
Topics: Adenine Nucleotides; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Benzenesulfonates; Child; Clofarabine; Cytarabine; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Recurrence; Sorafenib | 2011 |
Phase I and pharmacological study of cytarabine and tanespimycin in relapsed and refractory acute leukemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Benzoquinones; Checkpoint Kinase 1; Cytarabine; Female; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Leukemia; Male; Middle Aged; Protein Kinases; Recurrence; Time Factors | 2011 |
[Clinical study of kangai injection plus FLAG regimen for refractory/relapsed acute leukemia].
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drugs, Chinese Herbal; Female; Granulocyte Colony-Stimulating Factor; Humans; Injections; Leukemia; Male; Middle Aged; Vidarabine | 2011 |
Brief intensive therapy for older adults with newly diagnosed Burkitt or atypical Burkitt lymphoma/leukemia.
Topics: Adult; Aged; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Cyclophosphamide; Cytarabine; Drug Administration Schedule; Female; Humans; Injections, Spinal; Kaplan-Meier Estimate; Leukemia; Male; Methotrexate; Middle Aged; Mucositis; Neutropenia; Prednisone; Remission Induction; Rituximab; Time Factors; Treatment Outcome; Vincristine | 2013 |
Pharmacokinetics of CPX-351; a nano-scale liposomal fixed molar ratio formulation of cytarabine:daunorubicin, in patients with advanced leukemia.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia; Liposomes; Male; Middle Aged; Nanotechnology; Prognosis | 2012 |
Peripheral blood stem cell collection in children with acute leukemia: effectiveness of the 'DIAVE' mobilizing regimen.
Topics: Acute Disease; Adolescent; Adult; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Cell Count; Child; Child, Preschool; Cytarabine; Dexamethasone; Etoposide; Graft Survival; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Humans; Idarubicin; Leukapheresis; Leukemia; Peripheral Blood Stem Cell Transplantation; Vincristine | 2002 |
Phase 1 and pharmacodynamic studies of G3139, a Bcl-2 antisense oligonucleotide, in combination with chemotherapy in refractory or relapsed acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Down-Regulation; Female; Genes, bcl-2; Granulocyte Colony-Stimulating Factor; Humans; Leukemia; Male; Middle Aged; Oligonucleotides, Antisense; Remission Induction; Salvage Therapy; Thionucleotides; Vidarabine | 2003 |
Phase I trial of intrathecal liposomal cytarabine in children with neoplastic meningitis.
Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Catheters, Indwelling; Child; Child, Preschool; Cytarabine; Drug Delivery Systems; Female; Glioma; Humans; Injections, Spinal; Leukemia; Liposomes; Male; Maximum Tolerated Dose; Medulloblastoma; Meningeal Neoplasms; Spinal Puncture | 2004 |
Results of a phase 1-2 study of clofarabine in combination with cytarabine (ara-C) in relapsed and refractory acute leukemias.
Topics: Acute Disease; Adenine Nucleotides; Aged; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cytarabine; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Karyotyping; Leukemia; Male; Middle Aged; Recurrence; Treatment Outcome | 2005 |
Glomerular dysfunction, independent of tubular dysfunction, induced by antineoplastic chemotherapy in children.
Topics: Acute Disease; Adolescent; Albuminuria; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Creatinine; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Glomerular Filtration Rate; Humans; Kidney Tubules; Leukemia; Lymphoma; Methotrexate; Neoplasms; Neuroblastoma; Osteosarcoma; Proteinuria; Rhabdomyosarcoma; Vincristine | 2004 |
A phase I and pharmacologic study of idarubicin, cytarabine, etoposide, and the multidrug resistance protein (MDR1/Pgp) inhibitor PSC-833 in patients with refractory leukemia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cyclosporins; Cytarabine; Drug Interactions; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Idarubicin; Leukemia; Male; Maximum Tolerated Dose; Middle Aged; Treatment Outcome | 2005 |
Low-dose cytosine arabinoside (LD-AraC) vs LD-AraC plus granulocyte/macrophage colony stimulating factor vs LD-AraC plus Interleukin-3 for myelodysplastic syndrome patients with a high risk of developing acute leukemia: final results of a randomized phase
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Injections, Subcutaneous; Interleukin-3; Leukemia; Male; Middle Aged; Myelodysplastic Syndromes; Risk Factors; Treatment Outcome | 2005 |
Phase I study of cloretazine (VNP40101M), a novel sulfonylhydrazine alkylating agent, combined with cytarabine in patients with refractory leukemia.
Topics: Adult; Aged; Alkylating Agents; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Base Pair Mismatch; Cohort Studies; Cytarabine; Disease Progression; DNA; DNA Repair; Female; Humans; Hydrazines; Leukemia; Leukocytes, Mononuclear; Male; Middle Aged; Models, Chemical; O(6)-Methylguanine-DNA Methyltransferase; Sulfonamides; Time Factors | 2005 |
Prospective trial of high-dose chemotherapy followed by infusions of peripheral blood stem cells and dose-escalated donor lymphocytes for relapsed leukemia after allogeneic stem cell transplantation.
Topics: Adult; Antimetabolites, Antineoplastic; Cytarabine; Disease-Free Survival; Female; Graft vs Host Disease; Humans; Leukemia; Lymphocyte Transfusion; Male; Middle Aged; Peripheral Blood Stem Cell Transplantation; Prospective Studies; Recurrence; Remission Induction; Transplantation, Homologous; Treatment Outcome | 2005 |
A pharmacokinetic study of intra-CSF administered encapsulated cytarabine (DepoCyt) for the treatment of neoplastic meningitis in patients with leukemia, lymphoma, or solid tumors as part of a phase III study.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Cytarabine; Delayed-Action Preparations; Disease Progression; Female; Humans; Injections, Spinal; Leukemia; Lymphoma; Male; Meningeal Neoplasms; Meningitis; Middle Aged | 2007 |
Donor lymphocyte infusion for the treatment of leukemia relapse after HLA-mismatched/haploidentical T-cell-replete hematopoietic stem cell transplantation.
Topics: Adolescent; Adult; Antineoplastic Agents; Benzamides; Child; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Graft vs Host Disease; Graft vs Leukemia Effect; Haplotypes; Histocompatibility; HLA Antigens; Humans; Imatinib Mesylate; Immunosuppressive Agents; Kaplan-Meier Estimate; Leukemia; Lymphocyte Transfusion; Male; Methotrexate; Mitoxantrone; Pancytopenia; Peripheral Blood Stem Cell Transplantation; Piperazines; Pyrimidines; Recurrence; Remission Induction; Salvage Therapy; Tissue Donors; Treatment Outcome | 2007 |
Sequential oral hydroxyurea and intravenous cytosine arabinoside in refractory childhood acute leukemia: a pediatric oncology group phase 1 study.
Topics: Adolescent; Adult; Child; Child, Preschool; Cytarabine; Humans; Hydroxyurea; Infections; Leukemia; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Myeloid, Acute; Liver; Skin; Survival Analysis | 2008 |
Contrasting benefits of two maintenance programs following identical induction in children with acute nonlymphocytic leukemia: a report from the Childrens Cancer Study Group.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Child; Cyclophosphamide; Cytarabine; Humans; Leukemia; Thioguanine; Vincristine | 1984 |
[Results of cooperative clinical studies of cyclocytidine in leukemia in children and adults].
Topics: Adolescent; Adult; Aged; Ancitabine; Cancer Care Facilities; Child; Child, Preschool; Clinical Trials as Topic; Cytarabine; Follow-Up Studies; Humans; Infant; Interinstitutional Relations; Leukemia; Middle Aged; Remission, Spontaneous; USSR | 1980 |
Treatment of acute nonlymphocytic leukemia in adults: response to 2,2-anhydro-1-B-D-arabinofuranosyl-5-fluorocytosine and thioguanine on the L-12 protocol.
Topics: Adolescent; Adult; Aged; Ancitabine; Antineoplastic Agents; Bacterial Vaccines; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Pseudomonas aeruginosa; Random Allocation; Thioguanine | 1981 |
[Comparative study of 2 preparations of cyclocytidine (USSR, Japan) in leukemia patients].
Topics: Ancitabine; Child; Child, Preschool; Clinical Trials as Topic; Cytarabine; Humans; Leukemia | 1982 |
Sequential combination of systemic high-dose ara-C and asparaginase for the treatment of central nervous system leukemia and lymphoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Brain Neoplasms; Child; Clinical Trials as Topic; Cytarabine; Humans; Leukemia; Lymphoma; Male; Meningeal Neoplasms; Tomography, X-Ray Computed | 1984 |
Full dose versus attenuated dose daunorubicin, cytosine arabinoside, and 6-thioguanine in the treatment of acute nonlymphocytic leukemia in the elderly.
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Administration Schedule; Heart; Hemorrhage; Humans; Leukemia; Quality of Life; Random Allocation; Respiratory Distress Syndrome; Thioguanine | 1984 |
Reinduction chemotherapy for acute nonlymphocytic leukemia.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Doxorubicin; Female; Humans; Leukemia; Male; Middle Aged; Retrospective Studies; Thioguanine | 1984 |
Mitoxantrone as a single agent and in combination chemotherapy in patients with refractory acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Anthraquinones; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Clinical Trials as Topic; Cytarabine; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Prednisone; Vincristine | 1984 |
[Symposium on treatment of cancer. 1. Chemotherapy of acute leukemia in adults].
Topics: Aclarubicin; Acute Disease; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Clinical Trials as Topic; Cytarabine; Doxorubicin; Humans; Interferon Type I; Leukemia; Middle Aged; Naphthacenes | 1984 |
A randomized study of the efficacy of consolidation therapy in adult acute nonlymphocytic leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Central Nervous System Diseases; Chemical and Drug Induced Liver Injury; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Evaluation; Female; Humans; Leukemia; Male; Middle Aged; Random Allocation; Thioguanine; United States | 1984 |
In adult acute nonlymphoblastic leukaemia extended maintenance chemotherapy has no benefit.
Topics: Acute Disease; Adolescent; Adult; Cytarabine; Doxorubicin; Humans; Leukemia; Middle Aged; Podophyllotoxin; Prognosis | 1984 |
Topical corticosteroid therapy for corneal toxicity from systemically administered cytarabine.
Topics: Administration, Topical; Adrenal Cortex Hormones; Adult; Aged; Clinical Trials as Topic; Cornea; Cytarabine; Daunorubicin; Double-Blind Method; Female; Humans; Infusions, Parenteral; Keratitis; Leukemia; Male; Middle Aged; Ophthalmic Solutions | 1982 |
Adult acute leukemia studies utilizing cytarabine: early Southwest Oncology Group trials.
Topics: Adult; Clinical Trials as Topic; Cytarabine; Drug Therapy, Combination; Humans; Leukemia | 1982 |
Immunotherapy maintenance in acute non-lymphocytic leukaemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Humans; Hydroxyurea; Immunotherapy; Leukemia; Middle Aged; Prednisolone; Prognosis; Random Allocation; Vincristine | 1982 |
Adjuvant specific immunotherapy in maintenance treatment of adult acute non-lymphocytic leukemia.
Topics: Adolescent; Adult; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Immunotherapy; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Thioguanine; Vincristine | 1981 |
Cyclophosphamide, cytosine arabinoside and methotrexate versus cytosine arabinoside and thioguanine for acute non-lymphocytic leukemia in adults.
Topics: Adult; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Methotrexate; Middle Aged; Remission, Spontaneous; Thioguanine; Time Factors | 1980 |
[Combined chemotherapy: prednisone, cytosine arabinose and vincristine in the treatment of acute non-lymphoblastic leukemia in the adult].
Topics: Acute Disease; Adolescent; Aged; Clinical Trials as Topic; Cytarabine; Drug Synergism; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Prednisone; Vincristine | 1980 |
High-dose combination chemotherapy for acute nonlymphoblastic leukemia in adults.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents; Child; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Infections; Leukemia; Middle Aged; Prednisone; Prognosis; Remission, Spontaneous; Thioguanine; Vincristine | 1981 |
[Results of a clinical study of the preparation Lenvis in leukemias in children and adults].
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Clinical Trials as Topic; Cytarabine; Drug Therapy, Combination; Humans; Infant; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Middle Aged; Prednisolone; Thioguanine | 1981 |
[Development of new antileukemic agents].
Topics: Aclarubicin; Adolescent; Adult; Aged; Animals; Antibiotics, Antineoplastic; Clinical Trials as Topic; Cytarabine; Humans; Leukemia; Mice; Middle Aged; Naphthacenes | 1981 |
Sequential studies of daunorubicin and adriamycin in acute nonlymphocytic leukemia.
Topics: Acute Disease; Adult; Age Factors; Antineoplastic Agents; Clinical Trials as Topic; Cytarabine; Daunorubicin; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Humans; Leukemia | 1981 |
Prednimustine and vincristine compared with cytosine arabinoside and thioguanine for treatment of elderly patients with acute nonlymphoblastic leukemia.
Topics: Acute Disease; Aged; Blood Cell Count; Chlorambucil; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Middle Aged; Prednimustine; Thioguanine; Vincristine | 1982 |
Randomized trial of loperamide versus dose escalation of octreotide acetate for chemotherapy-induced diarrhea in bone marrow transplant and leukemia patients.
Topics: Adult; Aged; Antidiarrheals; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Cytarabine; Diarrhea; Female; Humans; Leukemia; Loperamide; Male; Middle Aged; Octreotide | 1995 |
Treatment with cytosine arabinoside and granulocyte colony-stimulating factor in patients with myelodysplastic syndrome and its leukemic phase.
Topics: Adult; Aged; Aged, 80 and over; Cytarabine; Drug Administration Schedule; Drug Therapy, Combination; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia; Male; Middle Aged; Myelodysplastic Syndromes; Recombinant Proteins; Remission Induction | 1994 |
Dexamethasone in the treatment of meningeal leukemia.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cell Count; Child; Cytarabine; Dexamethasone; Humans; Infant; Leukemia; Meningeal Neoplasms; Methotrexate; Middle Aged | 1995 |
Autologous bone marrow transplantation with alkyl-lysophospholipid-purged marrow.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Purging; Bone Marrow Transplantation; Combined Modality Therapy; Cryopreservation; Cyclophosphamide; Cytarabine; Etoposide; Female; Hematopoietic Stem Cells; Humans; Infections; Leukemia; Life Tables; Male; Middle Aged; Neoplastic Stem Cells; Phospholipid Ethers; Salvage Therapy; Survival Analysis; Tissue Preservation; Whole-Body Irradiation | 1993 |
Prognostic value of immunophenotyping in acute myeloid leukemia. Australian Leukaemia Study Group.
Topics: Acute Disease; Adolescent; Adult; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Daunorubicin; Etoposide; Follow-Up Studies; HLA-DR Antigens; Humans; Immunophenotyping; Leukemia; Middle Aged; Predictive Value of Tests; Prognosis; Survival Analysis; Time Factors | 1994 |
Phase I study of a continuous infusion of high-dose ara-C in conjunction with a fixed dose of 2'-deoxycytidine (IND 28108) in patients with refractory leukemia: an interim report.
Topics: Adult; Aged; Blast Crisis; Cytarabine; Deoxycytidine; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Middle Aged; Neutropenia; Remission Induction; Thrombocytopenia | 1993 |
A randomized phase II study of low-dose cytosine arabinoside (LD-AraC) plus granulocyte-macrophage colony-stimulating factor (rhGM-CSF) in myelodysplastic syndromes (MDS) with a high risk of developing leukemia. EORTC Leukemia Cooperative Group.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Cytarabine; Dose-Response Relationship, Drug; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia; Male; Middle Aged; Myelodysplastic Syndromes; Recombinant Proteins; Risk Factors | 1994 |
[Hypoplastic leukemia which achieved remission with administration of M-CSF along with low dose ara-C].
Topics: Aged; Cytarabine; Female; Humans; Leukemia; Macrophage Colony-Stimulating Factor; Remission Induction | 1993 |
Combination of quinine as a potential reversing agent with mitoxantrone and cytarabine for the treatment of acute leukemias: a randomized multicenter study.
Topics: Acute Disease; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Cytarabine; Drug Resistance, Multiple; Female; Hematopoiesis; Humans; Leukemia; Male; Middle Aged; Mitoxantrone; Quinine | 1996 |
CD6-depleted allogeneic bone marrow transplantation for acute leukemia in first complete remission.
Topics: Acute Disease; Adult; Antibiotics, Antineoplastic; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Purging; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Female; Graft Survival; Graft vs Host Disease; Humans; Infections; Leukemia; Life Tables; Lymphocyte Depletion; Male; Middle Aged; Neoplasms, Second Primary; Remission Induction; Risk; Survival Analysis; T-Lymphocyte Subsets; Transplantation, Homologous; Treatment Outcome | 1997 |
[Chemotherapy schedules and bacteremia in adult patients with acute leukemia].
Topics: Acute Disease; Adolescent; Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bacteremia; Cytarabine; Daunorubicin; Drug Therapy, Combination; Etoposide; Female; Humans; Leukemia; Male; Mitoxantrone; Neutropenia; Risk Factors | 1996 |
Phase I/II study of idarubicin given with continuous infusion fludarabine followed by continuous infusion cytarabine in children with acute leukemia: a report from the Children's Cancer Group.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Female; Humans; Idarubicin; Infant; Infusions, Intravenous; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Vidarabine | 1997 |
Navoban (tropisetron, ICS 205-930) and dexamethasone combination in the prevention of vomiting for patients receiving preconditioning high-dose chemotherapy before marrow transplantation.
Topics: Adolescent; Adult; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Carmustine; Child; Cyclophosphamide; Cytarabine; Dexamethasone; Dizziness; Drug Therapy, Combination; Female; Headache; Heartburn; Humans; Indoles; Leukemia; Male; Melphalan; Middle Aged; Multiple Myeloma; Podophyllotoxin; Transplantation Conditioning; Tropisetron; Vomiting; Whole-Body Irradiation | 1998 |
Tallimustine, an effective antileukemic agent in a severe combined immunodeficient mouse model of adult myelogenous leukemia, induces remissions in a phase I study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Agents; Cytarabine; Diarrhea; Distamycins; Drug Administration Schedule; Female; Humans; Injections, Intravenous; Leukemia; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Mice; Mice, SCID; Middle Aged; Nausea; Nitrogen Mustard Compounds; Transplantation, Heterologous; Tumor Cells, Cultured; Vomiting | 1997 |
A prospective study of autologous bone marrow or peripheral blood stem cell transplantation after intensive chemotherapy in myelodysplastic syndromes. Groupe Français des Myélodysplasies. Group Ouest-Est d'étude des Leucémies aiguës myéloïdes.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Cytarabine; Disease-Free Survival; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Life Tables; Male; Middle Aged; Mitoxantrone; Myelodysplastic Syndromes; Prognosis; Prospective Studies; Quinine; Remission Induction; Risk Factors; Survival Analysis; Survival Rate; Transplantation Conditioning; Transplantation, Autologous | 1999 |
Addition of high-dose Ara-C to the BMT conditioning regimen reduces leukemia relapse without an increase in toxicity.
Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Humans; Leukemia; Male; Middle Aged; Recurrence; Transplantation Conditioning | 1999 |
Cyclophosphamide, ara-C and topotecan (CAT) for patients with refractory or relapsed acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Humans; Leukemia; Middle Aged; Recurrence; Topotecan; Treatment Outcome | 2000 |
Mitoxantrone, etoposide, carboplatinum and ara-C combination therapy (MECA) in refractory and relapsed acute leukemia.
Topics: Actuarial Analysis; Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cytarabine; Disease-Free Survival; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Male; Middle Aged; Mitoxantrone; Recurrence; Risk Factors; Salvage Therapy; Treatment Outcome | 2000 |
Efficacy of fludarabine, intermittent sequential high-dose cytosine arabinoside, and mitoxantrone (FIS-HAM) salvage therapy in highly resistant acute leukemias.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Drug Administration Schedule; Drug Resistance; Humans; Leukemia; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Salvage Therapy; Therapeutic Equivalency; Treatment Outcome; Vidarabine | 2001 |
Phase I trial with escalating doses of idarubicin and multidrug resistance reversal by short-course cyclosporin A, sequential high-dose cytosine arabinoside, and granulocyte colony-stimulating factor for adult patients with refractory acute leukemia.
Topics: Acute Disease; Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cyclosporine; Cytarabine; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia; Male; Maximum Tolerated Dose; Middle Aged; Salvage Therapy; Treatment Outcome | 2002 |
Randomized, double-blind, crossover, placebo-controlled trial of intravenous ondansetron for the prevention of intrathecal chemotherapy-induced vomiting in children.
Topics: Adolescent; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cross-Over Studies; Cytarabine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Headache; Humans; Hydrocortisone; Injections, Intravenous; Leukemia; Male; Mercaptopurine; Methotrexate; Nausea; Ondansetron; Risk; Serotonin Antagonists; Treatment Outcome; Vincristine; Vomiting | 2001 |
Daunomycin, cytosine arabinoside and 6-thioguanine (DAT) vs vincristine, cytosine arabinoside and 6-thioguanine (VAT) in the induction treatment of acute nonlymphocyte leukemia: a randomized collaborative study.
Topics: Adolescent; Adult; Antineoplastic Agents; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Prednisone; Remission, Spontaneous; Thioguanine; Time Factors; Vincristine | 1978 |
The effect of thioguanine on a combination of daunorubicine, cytarabine and prednisone in the treatment of acute leukaemia in adults. The Finnish Leukaemia Group.
Topics: Acute Disease; Adolescent; Adult; Aged; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Middle Aged; Prednisone; Prognosis; Remission, Spontaneous; Thioguanine | 1979 |
Randomized clinical trial of cystosine arabinoside and 6-thioguanine in remission induction and consolidation of adult nonlymphocytic acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Bone Marrow; Clinical Trials as Topic; Cytarabine; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Middle Aged; Remission, Spontaneous; Thioguanine | 1977 |
Increased survival in childhood acute nonlymphocytic leukemia after treatment with prednisone, cytosine arabinoside, 6-thioguanine, cyclophosphamide, and oncovin (PATCO) combination chemotherapy.
Topics: Acute Disease; Adolescent; Antineoplastic Agents; Child; Child, Preschool; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia; Leukocyte Count; Male; Prednisone; Prognosis; Remission, Spontaneous; Thioguanine; Vincristine | 1978 |
Limited activity of ICRF-159 in advanced acute leukemia.
Topics: Clinical Trials as Topic; Cytarabine; Drug Therapy, Combination; Humans; Leukemia; Leukemia, Lymphoid; Piperazines; Razoxane | 1979 |
Phase I evaluation of tetrahydrouridine combined with cytosine arabinoside.
Topics: Bone Marrow; Clinical Trials as Topic; Cytarabine; Drug Evaluation; Drug Synergism; Drug Therapy, Combination; Humans; Leukemia; Lymphoma; Middle Aged; Neoplasms; Nucleoside Deaminases; Pyrimidine Nucleosides; Tetrahydrouridine; Uridine | 1979 |
Interhospital differences in the treatment of acute leukaemia in adults. The Finnish Leukaemia Group.
Topics: Acute Disease; Adult; Aged; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Finland; Humans; Leukemia; Leukemia, Myeloid, Acute; Middle Aged; Prednisone; Prognosis; Remission, Spontaneous | 1979 |
Refractory anemia with excess of blast cells: prognostic factors and effect of treatment with androgens or cytosine arabinoside. Results of a prospective trial in 58 patients. Cooperative Group for the Study of Aplastic and Refractory Anemias.
Topics: Acute Disease; Adult; Aged; Anemia, Aplastic; Bone Marrow; Clinical Trials as Topic; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged; Preleukemia; Prognosis; Testosterone Congeners | 1979 |
[Revaluation of the two step DCMP chemotherapy for acute leukemias (author's transl)].
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisolone | 1979 |
Prophylactic CNS therapy in childhood acute leukemia: review of methods used.
Topics: Antineoplastic Agents; Catheters, Indwelling; Central Nervous System; Central Nervous System Diseases; Child; Clinical Trials as Topic; Cytarabine; Drug Therapy, Combination; Humans; Hydrocortisone; Injections, Intraventricular; Injections, Spinal; Leukemia; Leukemia, Lymphoid; Methotrexate; Radiotherapy; Radiotherapy Dosage; Time Factors | 1979 |
Treatment of acute nonlymphoid leukaemia with five different schedules including cytosine arabinoside and 6-thioguanine.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Asparaginase; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Middle Aged; Thioguanine; Vincristine | 1977 |
Intensification of remission induction therapy for acute nonlymphocytic leukemia (ANLL). I. Response and toxicity in four different regimens.
Topics: Acute Disease; Age Factors; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Ifosfamide; Leukemia; Methods; Middle Aged; Thioguanine; Vincristine | 1979 |
Combination intrathecal therapy for meningeal leukemia: two versus three drugs.
Topics: Brain Neoplasms; Child; Cytarabine; Drug Therapy, Combination; Humans; Hydrocortisone; Injections, Spinal; Leukemia; Meninges; Methotrexate; Remission, Spontaneous | 1977 |
Chemotherapy of acute leukemia: a comparison of vincristine, cytarabine, and prednisone alone and in combination with cyclophosphamide or daunorubicin.
Topics: Acute Disease; Adult; Aged; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Humans; Leukemia; Male; Middle Aged; Prednisone; Remission, Spontaneous; Time Factors; Vincristine | 1978 |
Early consolidation chemotherapy for adults with acute leukemia in remission.
Topics: Acute Disease; Adolescent; Adult; Anti-Bacterial Agents; Antineoplastic Agents; Bacterial Infections; Cytarabine; Enterocolitis, Pseudomembranous; Female; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Necrosis; Prednisone; Remission, Spontaneous; Vincristine | 1976 |
A study of intermittent alternating drug program reinduction therapy on the frequency and duration of response in adult acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Agents; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Drug Administration Schedule; Female; Humans; Infant; Infant, Newborn; Leukemia; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Remission, Spontaneous; Vincristine | 1976 |
Study of cytosine arabinoside (NSC-63878) synchronization plus vincristine (NSC-67574), prednisone (NSC-10023), and L-asparaginase (NSC-109229) for remission induction in advanced acute leukemia in children.
Topics: Acute Disease; Adolescent; Antineoplastic Agents; Asparaginase; Cell Division; Cells, Cultured; Child; Cytarabine; DNA, Neoplasm; Drug Therapy, Combination; Humans; Leukemia; Prednisone; Remission, Spontaneous; Vincristine | 1976 |
Progress in the treatment of adults with acute leukemia: review of regimens containing cytarabine studied by the Southwest Oncology Group.
Topics: Acute Disease; Adult; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Humans; Leukemia; Leukemia, Lymphoid; Middle Aged; Prednisone; Vincristine | 1976 |
Randomized clinical comparison of daunorubicin (NSC-82151) alone with a combination of daunorubicin, cytosine arabinoside (NSC-63878), 6-thioguanine (NSC-752), and pyrimethamine (NSC-3061) for the treatment of acute nonlymphocytic leukemia.
Topics: Acute Disease; Aged; Antineoplastic Agents; Bone Marrow; Central Nervous System Diseases; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Guanazole; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Meninges; Middle Aged; Pyrimethamine; Remission, Spontaneous; Skin Tests; Thioguanine | 1976 |
Cell kinetics in leukemia. Correlation with clinical features and response to chemotherapy.
Topics: Bone Marrow; Bone Marrow Cells; Cytarabine; Daunorubicin; DNA, Neoplasm; Drug Therapy, Combination; Humans; Kinetics; Leucovorin; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Methotrexate; Mitotic Index; Thioguanine | 1975 |
An attempt at synchronization of marrow cells in acute leukemia: relationship to therapeutic response.
Topics: Adult; Age Factors; Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Cell Division; Cytarabine; Female; Humans; Leucovorin; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Male; Methotrexate; Middle Aged; Remission, Spontaneous; Sex Factors; Vincristine | 1976 |
[Clinical use of cytosine arabinoside in infancy. I. Cytosine arabinoside in the treatment of acute leukosis].
Topics: Acute Disease; Adolescent; Child; Child, Preschool; Clinical Trials as Topic; Cytarabine; Drug Evaluation; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male | 1975 |
[Results of therapy in acute leukemia in adults. Comparison of different combinations of cytotoxic drugs].
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Aminosalicylic Acids; Antineoplastic Agents; Cytarabine; Drug Combinations; Esterases; Histocytochemistry; Humans; Leukemia; Mercaptopurine; Methotrexate; Middle Aged; Peroxidases; Prednisone; Prognosis; Remission, Spontaneous; Vincristine | 1975 |
[Experience with using aclarubicin in the treatment of acute leukemia and blast crisis of chronic myeloid leukemia].
Topics: Aclarubicin; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Cytarabine; Humans; Leukemia; Leukemia, Monocytic, Acute; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction | 1992 |
Treatment of myelodysplastic syndromes (MDS) and high leukaemic risk with low-dose cytosine arabinoside (LD-AraC) plus granulocyte-macrophage colony-stimulating factor (rh GM-CSF). The EORTC Leukaemia Group.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anemia, Refractory, with Excess of Blasts; Bone Marrow; Cytarabine; Drug Administration Schedule; Drug Therapy, Combination; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Injections, Subcutaneous; Leukemia; Male; Middle Aged; Risk Factors; Survival Rate | 1992 |
Low-dose cytosine arabinoside for treating hypocellular acute leukemia in the elderly.
Topics: Acute Disease; Age Factors; Aged; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Injections, Subcutaneous; Leukemia; Male; Middle Aged; Time Factors | 1992 |
Phase I study of busulfan, cyclophosphamide, and timed sequential escalating doses of cytarabine followed by bone marrow transplantation.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Drug Administration Schedule; Drug Evaluation; Female; Graft vs Host Disease; Humans; Leukemia; Lymphoma; Male; Middle Aged | 1992 |
Ceftazidime as initial therapy in febrile patients with acute leukemia during induction chemotherapy. Leukemia Group of Middle Sweden.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bacterial Infections; Ceftazidime; Cytarabine; Daunorubicin; Female; Fever; Fever of Unknown Origin; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Thioguanine | 1992 |
Current pharmacological treatment approaches to central nervous system leukaemia.
Topics: Adolescent; Adult; Antineoplastic Agents; Central Nervous System Diseases; Child; Child, Preschool; Cytarabine; Drug Evaluation; Humans; Infant; Infant, Newborn; Leukemia; Meningeal Neoplasms; Methotrexate | 1991 |
Therapy of refractory/relapsed acute leukemia with cytosine arabinoside plus tetrahydrouridine (an inhibitor of cytidine deaminase)--a pilot study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Drug Evaluation; Female; Humans; Leukemia; Male; Metabolic Clearance Rate; Middle Aged; Tetrahydrouridine | 1991 |
[A trial of the use of high doses of cytosar with autologous bone marrow protection in acute leukemias].
Topics: Acute Disease; Adolescent; Adult; Blood Cells; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Female; Humans; Leukemia; Male; Recurrence; Remission Induction; Time Factors; Transplantation, Autologous | 1990 |
Induction failures in childhood acute nonlymphocytic leukemia: etoposide/5-azacytidine for cases refractory to daunorubicin/cytarabine.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Child; Clinical Trials as Topic; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia; Male | 1986 |
Bone marrow transplantation for the treatment of leukaemia-results of the Munich Cooperative Group.
Topics: Adolescent; Adult; Bone Marrow Transplantation; Carmustine; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Female; Germany, West; Graft vs Host Disease; Humans; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Middle Aged; Multicenter Studies as Topic; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Survival Rate; Whole-Body Irradiation | 1989 |
An in vitro method which assesses corneal epithelial toxicity due to antineoplastic, preservative and antimicrobial agents.
Topics: Adult; Aged; Aminoglycosides; Animals; Antineoplastic Agents; Antiviral Agents; Cells, Cultured; Cornea; Cytarabine; Deoxycytidine; Double-Blind Method; Epithelium; Female; Hodgkin Disease; Humans; Keratitis; Leukemia; Male; Middle Aged; Preservatives, Pharmaceutical; Rabbits; Thymidine; Toxicology | 1989 |
[Intermediate-dose cytosine arabinoside therapy in refractory acute leukemia].
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cytarabine; Doxorubicin; Drug Resistance; Female; Humans; Leukemia; Male; Middle Aged; Multicenter Studies as Topic; Remission Induction; Vincristine | 1989 |
Idarubicin in acute leukemias: experience of the Italian Cooperative Group GIMEMA.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Female; Humans; Idarubicin; Leukemia; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Random Allocation; Remission Induction | 1989 |
Idarubicin in acute leukemia: results of studies at Memorial Sloan-Kettering Cancer Center.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Cytarabine; Daunorubicin; Female; Humans; Idarubicin; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Remission Induction | 1989 |
[Value of high-dose cytosine-arabinoside in the treatment of resistant acute leukemia].
Topics: Acute Disease; Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Cytarabine; Drug Resistance; Humans; Infusions, Intravenous; Leukemia; Middle Aged; Neoplasm Recurrence, Local | 1987 |
[A study of B-triple V (behenoyl-ara C, etoposide, vincristine, vinblastine) in acute leukemia].
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Etoposide; Female; Humans; Leukemia; Male; Middle Aged; Vinblastine; Vincristine | 1988 |
Central nervous system leukemia.
Topics: Child; Clinical Trials as Topic; Combined Modality Therapy; Cytarabine; Humans; Leukemia; Meningeal Neoplasms; Methotrexate; Radiotherapy Dosage | 1988 |
[Urotoxicity of enocitabine (BH-AC) and aclarubicin (ACM) in pediatric patients with hematological malignancies].
Topics: Aclarubicin; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Female; Hematuria; Humans; Infant; Leukemia; Lymphoma; Male; Multicenter Studies as Topic; Retrospective Studies | 1988 |
Antithrombin III during high-dose cytosine arabinoside therapy with or without asparaginase.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Antithrombin III; Asparaginase; Cytarabine; Female; Humans; Leukemia; Liver; Lymphoma; Male; Middle Aged | 1986 |
The role of mitozantrone in the treatment of acute leukaemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Clinical Trials as Topic; Combined Modality Therapy; Cytarabine; Humans; Leukemia; Mitoxantrone | 1987 |
High-dose cytarabine and total body irradiation with or without cyclophosphamide as a preparative regimen for marrow transplantation for acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Humans; Immunosuppression Therapy; Infant; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid | 1988 |
Maintenance chemotherapy prolongs remission duration in adult acute nonlymphocytic leukemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Administration Schedule; Follow-Up Studies; Humans; Leukemia; Thioguanine | 1988 |
Intensive postremission therapy in adults with acute nonlymphocytic leukemia using various dose schedules of ara-C: a progress report from the CALGB. Cancer and Leukemia Group B.
Topics: Acute Disease; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Evaluation; Humans; Leukemia; Middle Aged; Prognosis | 1987 |
Treatment of childhood acute nonlymphocytic leukemia with individually scheduled high doses of cytarabine: preliminary results of study ANLL-82 of the Dutch Childhood Leukemia Study Group (DCLSG).
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Clinical Trials as Topic; Cytarabine; Doxorubicin; Drug Administration Schedule; Female; Humans; Leukemia; Male; Netherlands; Prednisolone; Vincristine | 1987 |
[Treatment of acute nonlymphoblastic leukemia in childhood: results of protocol ANLL-827 and ANLL-861 studies. Children's Cancer and Leukemia Study Group].
Topics: Acute Disease; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Combinations; Humans; Leukemia; Prednisone; Remission Induction; Vincristine | 1987 |
Intensive maintenance therapy improves survival in adult acute nonlymphocytic leukemia: an eight-year follow-up.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Central Nervous System Diseases; Cytarabine; Evaluation Studies as Topic; Female; Follow-Up Studies; Humans; Immunotherapy; Leukemia; Male; Middle Aged; Neuraminidase; Remission Induction; Splenectomy; Thioguanine | 1988 |
Overview of the clinical relevance of autologous bone marrow transplantation.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmustine; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Drug Evaluation; Drug Resistance; Etoposide; Hodgkin Disease; Humans; Leukemia; Leukemia, Lymphoid; Lymphoma; Melphalan; Neoplasm Recurrence, Local; Neoplasms; Thioguanine; Transplantation, Autologous | 1986 |
[A phase III study of BHAC-MMP (behenoyl-ara-C, mitoxantrone, 6-mercaptopurine prednisolone) in acute leukemia. Hanshin Cooperative Study Group of Hematological Disorders].
Topics: Acute Disease; Adolescent; Adult; Aged; Anthraquinones; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Female; Humans; Leukemia; Leukemia, Lymphoid; Male; Mercaptopurine; Middle Aged; Mitoxantrone; Prednisolone | 1986 |
[Mitoxantrone as combination chemotherapy in patients with acute leukemia. Tokai Blood Cancer Study Group].
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Clinical Trials as Topic; Cytarabine; Female; Humans; Leukemia; Male; Mercaptopurine; Middle Aged; Mitoxantrone; Prednisolone; Vincristine | 1986 |
A new regimen of amsacrine with high-dose cytarabine is safe and effective therapy for acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Clinical Trials as Topic; Cytarabine; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged | 1987 |
Comparison of three remission induction regimens and two postinduction strategies for the treatment of acute nonlymphocytic leukemia: a cancer and leukemia group B study.
Topics: Acute Disease; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Humans; Leukemia; Prognosis; Random Allocation; Remission Induction; Research Design; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination | 1987 |
A strategy for evaluation of new treatments in untreated patients: application to a clinical trial of AMSA for acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Doxorubicin; Humans; Leukemia; Middle Aged; Prednisone; Prognosis; Time Factors; Vincristine | 1987 |
Effect of amsacrine on ara-CTP cellular pharmacology in human leukemia cells during high-dose cytarabine therapy.
Topics: Acute Disease; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cells, Cultured; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged | 1987 |
Growth response of residual leukemia after initial drug therapy.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cytarabine; Daunorubicin; Humans; Leukemia; Middle Aged | 1986 |
Treatment of patients with acute nonlymphocytic leukemia in relapse: a Leukemia Intergroup study.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartate Aminotransferases; Clinical Trials as Topic; Cytarabine; Daunorubicin; Doxorubicin; Female; Humans; Leukemia; Leukocyte Count; Male; Middle Aged; Platelet Count | 1985 |
High rate of long-term survival in adult acute leukemia following ten-day chemotherapy (OAP) induction. Maintenance with chemotherapy or chemotherapy plus BCG vaccine.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Clinical Trials as Topic; Cytarabine; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisone; Random Allocation; Sex Factors; Time Factors; Vincristine | 1985 |
Sequential high-dose ara-C and asparaginase in the therapy of previously treated and untreated patients with acute leukemia.
Topics: Aging; Animals; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Asparaginase; Child; Clinical Trials as Topic; Cytarabine; Daunorubicin; DNA; Dose-Response Relationship, Drug; Drug Resistance; Humans; Kinetics; Leukemia; Leukemia, Lymphoid; Middle Aged; Time Factors | 1985 |
Dose-related pharmacologic effects of high-dose ara-C and its self-potentiation.
Topics: Aging; Animals; Arabinofuranosyluracil; Biological Transport; Bone Marrow; Cell Line; Cell Membrane; Clinical Trials as Topic; Cytarabine; DNA; Dose-Response Relationship, Drug; Drug Resistance; Half-Life; Humans; Interphase; Leukemia; Leukemia L5178; Time Factors | 1985 |
Sequential studies on the role of mitoxantrone in the treatment of acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Agranulocytosis; Anthraquinones; Antineoplastic Agents; Bone Marrow Transplantation; Clinical Trials as Topic; Cytarabine; Female; Heart; Humans; Leukemia; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Nausea; Stroke Volume; Vomiting | 1985 |
High-dose cytosine arabinoside therapy with and without anthracycline antibiotics for remission reinduction of acute nonlymphoblastic leukemia.
Topics: Acute Disease; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Blood Cells; Bone Marrow; Clinical Trials as Topic; Cytarabine; Daunorubicin; Doxorubicin; Humans; Leukemia; Naphthacenes; Time Factors | 1985 |
[High-dose cytosine arabinoside in acute leukemia: a cooperative study].
Topics: Acute Disease; Adolescent; Adult; Child; Clinical Trials as Topic; Cytarabine; Drug Resistance; Female; Humans; Leukemia; Male; Middle Aged | 1985 |
Treatment of leukemia with low dose Ara-C: a study of 159 cases.
Topics: Acute Disease; Aged; Clinical Trials as Topic; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia; Leukemia, Lymphoid; Middle Aged | 1985 |
The epipodophyllotoxin VP16-213 in combination chemotherapy for adults with acute nonlymphoblastic leukaemia.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Doxorubicin; Etoposide; Humans; Leukemia; Podophyllotoxin; Thioguanine | 1985 |
A therapeutic trial with low-dose cytarabine in myelodysplastic syndromes and acute leukemia.
Topics: Acute Disease; Aged; Bone Marrow Diseases; Clinical Trials as Topic; Cytarabine; Drug Administration Schedule; Humans; Leukemia; Middle Aged; Syndrome; Time Factors | 1985 |
[Results of follow-up studies on prognosis after immunotherapy with bestatin in acute nonlymphocytic leukemia].
Topics: Aclarubicin; Acute Disease; Adjuvants, Immunologic; Adolescent; Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Follow-Up Studies; Humans; Leucine; Leukemia; Mercaptopurine; Middle Aged; Naphthacenes; Prednisolone; Prognosis; Random Allocation | 1986 |
Cytarabine for acute leukemia in adults. Effect of schedule on therapeutic response.
Topics: Acute Disease; Adult; Blood Cell Count; Blood Platelets; Cytarabine; Female; Hemoglobinometry; Humans; Infusions, Parenteral; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Regression, Spontaneous; Remission, Spontaneous; Sex Factors; Time Factors | 1974 |
Chemotherapy of acute leukemia. Comparison of cytarabine alone and in combination with vincristine, prednisone, and cyclophosphamide.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Anemia; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocyte Count; Leukopenia; Male; Middle Aged; Nausea; Prednisone; Time Factors; Vincristine; Vomiting | 1974 |
Current trends in clinical pharmacology in the USA.
Topics: Animals; Asparaginase; Burkitt Lymphoma; Cannabis; Carcinogens; Clinical Trials as Topic; Contraceptives, Oral; Cyclamates; Cyclophosphamide; Cytarabine; Female; Humans; Legislation, Drug; Leukemia; Pharmacology; Psychology, Adolescent; Substance-Related Disorders; Thromboembolism; United States; United States Food and Drug Administration; Uterine Cervical Neoplasms | 1970 |
Clinical trials of 1-beta-D-arabinofuranosyl cytosine and 1,3-bis-(2-chloroethyl)-1-nitrosourea combination in metastatic cancer and acute leukemia.
Topics: Age Factors; Blood Cell Count; Blood Platelets; Blood Urea Nitrogen; Clinical Trials as Topic; Cytarabine; Drug Synergism; Female; Hemoglobins; Humans; Injections, Intravenous; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Neoplasm Metastasis; Neoplasms; Nitrogen Mustard Compounds; Nitroso Compounds; Nitrosourea Compounds; Remission, Spontaneous; Reticulocytes; Sex Factors; Urea; Uric Acid | 1971 |
Therapy of acute leukemia with the combination of cytosine arabinoside (NSC-63878) and cyclophosphamide (NSC-26271).
Topics: Acute Disease; Adolescent; Adult; Aged; Alanine Transaminase; Alopecia; Aspartate Aminotransferases; Bone Marrow Diseases; Child; Clinical Trials as Topic; Cyclophosphamide; Cystitis; Cytarabine; Drug Combinations; Evaluation Studies as Topic; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphoma, Large B-Cell, Diffuse; Male; Middle Aged; Nausea; Remission, Spontaneous; Vomiting | 1970 |
1007 other study(ies) available for cytarabine and Leukemia
| Article | Year |
|---|---|
Blood group gene specified glycosyltransferases in rare ABO groups and in leukaemia.
Topics: ABO Blood-Group System; Erythrocytes; Fucosyl Galactose alpha-N-Acetylgalactosaminyltransferase; Galactosyltransferases; Guanosine Diphosphate Fucose; Hexosyltransferases; Humans; Leukemia; Pedigree; Phenotype; Transferases | 1978 |
Variation of levels of plasma guanosine diphosphate L-fucose:beta-D-galactosyl alpha-2-L-fucosyltransferase in acute adult leukemia.
Topics: Acute Disease; Adult; Aged; Female; Fucose; Galactose; Guanosine Diphosphate Fucose; Hexosyltransferases; Humans; Leukemia; Male; Middle Aged | 1977 |
Nucleosides and nucleotides. 94. Radical deoxygenation of tert-alcohols in 1-(2-C-alkylpentofuranosyl) pyrimidines: synthesis of (2'S)-2'-deoxy-2'-C-methylcytidine, an antileukemic nucleoside.
Topics: Animals; Antimetabolites, Antineoplastic; Deoxycytidine; Drug Screening Assays, Antitumor; Humans; Indicators and Reagents; Leukemia; Leukemia L1210; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Molecular Structure; Neoplasms; Structure-Activity Relationship | 1991 |
Amino acid phosphoramidate nucleosides: potential ADEPT/GDEPT substrates.
Topics: Acid Phosphatase; Amides; Cell Division; Enzymes; Humans; Leukemia; Nucleosides; Phosphoric Acids; Protein Tyrosine Phosphatases; Substrate Specificity; Tumor Cells, Cultured | 2001 |
Structure-activity relationship and molecular mechanisms of ethyl 2-amino-4-(2-ethoxy-2-oxoethyl)-6-phenyl-4h-chromene-3-carboxylate (sha 14-1) and its analogues.
Topics: Apoptosis; Benzopyrans; Camptothecin; Cell Line, Tumor; Drug Resistance, Neoplasm; Humans; Leukemia; Mitoxantrone; Structure-Activity Relationship | 2009 |
Natural Product Micheliolide (MCL) Irreversibly Activates Pyruvate Kinase M2 and Suppresses Leukemia.
Topics: Acetylation; Active Transport, Cell Nucleus; Amino Acid Sequence; Animals; Antineoplastic Agents; Carcinogenesis; Carrier Proteins; Cell Line, Tumor; Cell Nucleus; Enzyme Activation; Gene Expression Regulation, Neoplastic; Humans; Leukemia; Membrane Proteins; Phosphorylation; Protein Domains; Protein Multimerization; Protein Structure, Quaternary; Sesquiterpenes, Guaiane; Substrate Specificity; Thyroid Hormone-Binding Proteins; Thyroid Hormones; Xenograft Model Antitumor Assays; Zebrafish | 2018 |
Angiokeratoma-like purpuric palmar nodules following chemotherapy.
Topics: Angiokeratoma; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Diagnosis, Differential; Female; Hand Dermatoses; Humans; Hydroxyurea; Leukemia; Methotrexate; Middle Aged; Purpura; Skin Neoplasms | 2021 |
Alterations in sphingolipid composition and mitochondrial bioenergetics represent synergistic therapeutic vulnerabilities linked to multidrug resistance in leukemia.
Topics: Cytarabine; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; HL-60 Cells; Humans; Leukemia; Mitochondria; Oxidative Phosphorylation; Sphingolipids; Vincristine | 2022 |
Topics: Apoptosis; Artesunate; Caspase 3; Caspase 9; Cell Line; Cytarabine; Daunorubicin; Humans; Leukemia; Leukemia, Myeloid, Acute; Mutation; Retrospective Studies | 2022 |
Synergistic interactions of cytarabine-adavosertib in leukemic cell lines proliferation and metabolomic endpoints.
Topics: Cell Line; Cell Proliferation; Cytarabine; Humans; Leukemia; Leukocytes, Mononuclear | 2023 |
Multiple lineage switches in KMT2A rearranged infant leukemia, responsive to combination therapy with CPX-351 and inotuzumab.
Topics: Cytarabine; Daunorubicin; Humans; Infant; Leukemia | 2023 |
Disrupting the leukemia niche in the central nervous system attenuates leukemia chemoresistance.
Topics: Animals; Central Nervous System; Cytarabine; Drug Resistance, Neoplasm; Humans; Leukemia; Mice; Quality of Life; Tumor Microenvironment | 2020 |
Acute leukemias in 2020: state of the art.
Topics: Acute Disease; Aminopyridines; Antineoplastic Agents; Antineoplastic Agents, Immunological; Congresses as Topic; Cytarabine; Daunorubicin; fms-Like Tyrosine Kinase 3; Gemtuzumab; Glycine; Humans; Leukemia; Pyridines; Recombinant Fusion Proteins; Staurosporine; Triazines | 2020 |
Physical interaction between BAALC and DBN1 induces chemoresistance in leukemia.
Topics: Antimetabolites, Antineoplastic; Cytarabine; Drug Resistance, Neoplasm; Gene Expression Regulation, Leukemic; HEK293 Cells; Humans; Jurkat Cells; Leukemia; Neoplasm Proteins; Neuropeptides; Protein Interaction Maps | 2021 |
Drug ranking using machine learning systematically predicts the efficacy of anti-cancer drugs.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Computational Biology; Cytarabine; Drug Screening Assays, Antitumor; Hep G2 Cells; Humans; Leukemia; Machine Learning; Neoplasms; Prognosis; Proteomics | 2021 |
Cafestol, a diterpene molecule found in coffee, induces leukemia cell death.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; CD11b Antigen; Cell Cycle Checkpoints; Cell Proliferation; Cell Survival; Coffea; Cytarabine; Diterpenes; Dose-Response Relationship, Drug; Fucosyltransferases; Hematopoietic Stem Cells; HL-60 Cells; Humans; K562 Cells; Leukemia; Lewis X Antigen; Male; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Phosphatidylserines; Phytotherapy; Plants, Medicinal; Reactive Oxygen Species | 2017 |
Release of Danger-Associated Molecular Patterns following Chemotherapy Does Not Induce Immunoparalysis in Leukemia Patients.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Biomarkers; Case-Control Studies; Cells, Cultured; Cholesterol, LDL; Cytarabine; Cytokines; DNA; DNA, Mitochondrial; Female; HLA-DR Antigens; Humans; Idarubicin; Leukemia; Leukemia, Myeloid, Acute; Leukocytes; Lipopolysaccharides; Male; Middle Aged; Myelodysplastic Syndromes; Young Adult | 2017 |
Repression of oxidative phosphorylation sensitizes leukemia cell lines to cytarabine.
Topics: Antimetabolites, Antineoplastic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytarabine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Gene Expression; Glycolysis; HL-60 Cells; Humans; K562 Cells; Leukemia; Oxidative Phosphorylation; Oxygen Consumption; STAT3 Transcription Factor | 2018 |
Systematic patient involvement for homebased outpatient administration of complex chemotherapy in acute leukemia and lymphoma.
Topics: Acute Disease; Adult; Aged; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cytarabine; Female; Humans; Infusion Pumps; Leukemia; Lymphoma; Male; Melphalan; Middle Aged; Outpatients; Podophyllotoxin | 2018 |
Peptides and small molecules blocking the CXCR4/CXCL12 axis overcome bone marrow‑induced chemoresistance in acute leukemias.
Topics: Bone Marrow; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chemokine CXCL12; Cytarabine; Drug Resistance, Neoplasm; Humans; Leukemia; Molecular Dynamics Simulation; Peptides; Protein Binding; Receptors, CXCR4; Signal Transduction; Small Molecule Libraries; Structure-Activity Relationship | 2019 |
Chemotherapy-induced skin toxicity and capillary leak syndrome.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capillary Leak Syndrome; Clofarabine; Cytarabine; Erythema; Female; Humans; Leukemia; Male; Middle Aged; Skin; Stevens-Johnson Syndrome | 2019 |
FLAG vs FLAG-IDA: outcomes in relapsed/refractory acute leukemias.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia; Middle Aged; Pakistan; Progression-Free Survival; Recurrence; Remission Induction; Retrospective Studies; Salvage Therapy; Survival Analysis; Survival Rate; Vidarabine; Young Adult | 2019 |
A novel bioluminescent bacterial biosensor for measurement of Ara-CTP and cytarabine potentiation by fludarabine in seven leukaemic cell lines.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Arabinofuranosylcytosine Triphosphate; Bacterial Proteins; Biosensing Techniques; Cell Line, Tumor; Cytarabine; HL-60 Cells; Humans; K562 Cells; Leukemia; Luminescent Measurements; Luminescent Proteins; Treatment Outcome; Vidarabine | 2013 |
Genetic inhibition of vascular endothelial growth factor receptor-1 significantly inhibits the migration and proliferation of leukemia cells and increases their sensitivity to chemotherapy.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Apoptosis; Bevacizumab; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cytarabine; HL-60 Cells; Humans; Leukemia; RNA Interference; RNA, Small Interfering; S Phase; U937 Cells; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2 | 2013 |
Acquired resistance of leukemic cells to AraC is associated with the upregulation of aldehyde dehydrogenase 1 family member A2.
Topics: Aldehyde Dehydrogenase 1 Family; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Doxorubicin; Drug Resistance, Neoplasm; Electrophoresis, Gel, Two-Dimensional; Enzyme Induction; Gene Expression Regulation, Leukemic; Humans; Idarubicin; K562 Cells; Leukemia; Leukemia, Erythroblastic, Acute; Neoplasm Proteins; Prodrugs; Retinal Dehydrogenase; RNA Interference; RNA, Small Interfering; Transfection; Up-Regulation | 2013 |
Primary treatment of leukemia relapses after allogeneic hematopoietic stem cell transplantation with reduced-intensity conditioning second transplantation from the original donor.
Topics: Adolescent; Adult; Cohort Studies; Cytarabine; Disease-Free Survival; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Male; Middle Aged; Recurrence; Transplantation Conditioning; Transplantation, Homologous; Young Adult | 2013 |
A novel three-dimensional stromal-based model for in vitro chemotherapy sensitivity testing of leukemia cells.
Topics: Antineoplastic Agents; Apoptosis; Bone Marrow Cells; Cadherins; Cell Culture Techniques; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Coculture Techniques; Cytarabine; Dose-Response Relationship, Drug; Doxorubicin; Flow Cytometry; HL-60 Cells; Humans; Immunohistochemistry; Ki-67 Antigen; Leukemia; Mesenchymal Stem Cells; Models, Biological | 2014 |
A versatile drug delivery system using streptavidin-tagged pegylated liposomes and biotinylated biomaterials.
Topics: Animals; Antibodies, Monoclonal; Antigens, CD7; Biological Transport; Biotinylation; Cell Survival; Chemistry, Pharmaceutical; Cytarabine; Dose-Response Relationship, Drug; Female; Fluoresceins; Fluorescent Dyes; Granulocyte Colony-Stimulating Factor; Humans; Inhibitory Concentration 50; Jurkat Cells; K562 Cells; Leukemia; Lipids; Liposomes; Mice; Mice, Inbred NOD; Mice, SCID; Polyethylene Glycols; Receptors, Granulocyte Colony-Stimulating Factor; Sialic Acid Binding Ig-like Lectin 3; Streptavidin; Technology, Pharmaceutical; Xenograft Model Antitumor Assays | 2013 |
Systematic dielectrophoretic analysis of the Ara-C-induced NB4 cell apoptosis combined with gene expression profiling.
Topics: Annexin A5; Apoptosis; Benzimidazoles; Carbocyanines; Cell Line, Tumor; Cluster Analysis; Cytarabine; Electric Conductivity; Electrophoresis; Gene Expression Profiling; Humans; Leukemia; Microscopy, Electron, Scanning; Real-Time Polymerase Chain Reaction | 2013 |
Cytosine arabinoside promotes cytotoxic effect of T cells on leukemia cells mediated by bispecific antibody.
Topics: Animals; Antibodies, Bispecific; B7-1 Antigen; B7-2 Antigen; Cell Line, Tumor; Cytarabine; Cytotoxicity, Immunologic; Female; Humans; Leukemia; Lymphocyte Activation; Mice; Mice, Nude; Mice, SCID; T-Lymphocytes | 2013 |
Human cytidine deaminase: a biochemical characterization of its naturally occurring variants.
Topics: Antineoplastic Agents; Catalysis; Cytarabine; Cytidine Deaminase; Humans; Kinetics; Leukemia; Mutagenesis, Site-Directed; Polymorphism, Single Nucleotide | 2014 |
Comparative study of autophagy inhibition by 3MA and CQ on Cytarabine‑induced death of leukaemia cells.
Topics: Adenine; Antimalarials; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Blotting, Western; Caspase 3; Cell Proliferation; Chloroquine; Cytarabine; Flow Cytometry; Fluorescent Antibody Technique; Humans; Immunophenotyping; Leukemia; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Tumor Cells, Cultured; Tumor Stem Cell Assay | 2014 |
Inhibition of mTOR-dependent autophagy sensitizes leukemic cells to cytarabine-induced apoptotic death.
Topics: AMP-Activated Protein Kinases; Antimetabolites, Antineoplastic; Apoptosis; Autophagy; Cell Line, Tumor; Cytarabine; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Leukemic; Humans; Leukemia; Leukocytes, Mononuclear; Proto-Oncogene Proteins c-akt; RNA Interference; Signal Transduction; TOR Serine-Threonine Kinases | 2014 |
[Effect of combined administration of Angelica polysaccharide and cytarabine on liver of human leukemia NOD/SCID mouse model].
Topics: Angelica; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cytarabine; Humans; K562 Cells; Leukemia; Liver; Male; Mice; Mice, SCID; Polysaccharides | 2014 |
Inhibition of miR-17 and miR-20a by oridonin triggers apoptosis and reverses chemoresistance by derepressing BIM-S.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Cell Growth Processes; Cytarabine; Diterpenes, Kaurane; Down-Regulation; Etoposide; HL-60 Cells; Humans; K562 Cells; Leukemia; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Microscopy, Confocal; Proto-Oncogene Proteins; Transfection; Up-Regulation | 2014 |
Sequential development of different acute leukemia types in the same patient.
Topics: Acute Disease; Antineoplastic Agents; Cytarabine; Humans; Idarubicin; Leukemia; Lymph Nodes; Male; Middle Aged; Neoplasm Recurrence, Local | 2014 |
Enlargement and multinucleation of u937 leukemia and MCF7 breast carcinoma cells by antineoplastic agents to enhance sensitivity to low frequency ultrasound and to DNA-directed anticancer agents.
Topics: Antineoplastic Agents; Cell Enlargement; Cell Nucleus; Cytarabine; Cytochalasin B; Doxorubicin; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Leukemia; MCF-7 Cells; Methotrexate; Mitomycin; Radiation-Sensitizing Agents; Sound | 2015 |
[Metformin Influences the Effect of Adipocytes on Leukemia Cell Chemoresistance through Regulation of Adipogenesis].
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; CCAAT-Enhancer-Binding Protein-alpha; Cell Differentiation; Cell Proliferation; Cytarabine; Drug Resistance, Neoplasm; Fatty Acid-Binding Proteins; Humans; Leukemia; Metformin; Mice; PPAR gamma; RNA, Messenger | 2015 |
[Effects of SDF-1/CXCR4 signal pathway blockade by AMD3100 on the adhesion of leukemia cells to osteoblast niche and the drug resistance of leukemia cells].
Topics: Apoptosis; Benzylamines; Cell Adhesion; Cell Line, Tumor; Chemokine CXCL12; Coculture Techniques; Cyclams; Cytarabine; Drug Resistance; Flow Cytometry; Heterocyclic Compounds; Humans; Leukemia; Mesenchymal Stem Cells; Osteoblasts; Receptors, CXCR4; Signal Transduction | 2015 |
Blockade of CD82 by a monoclonal antibody potentiates anti-leukemia effects of AraC in vivo.
Topics: Animals; Antibodies, Monoclonal; Antigens, CD34; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Cytarabine; Disease Models, Animal; Drug Synergism; Humans; Kangai-1 Protein; Leukemia; Mice; Mice, Transgenic; Xenograft Model Antitumor Assays | 2015 |
The hematopoietic tumor suppressor interferon regulatory factor 8 (IRF8) is upregulated by the antimetabolite cytarabine in leukemic cells involving the zinc finger protein ZNF224, acting as a cofactor of the Wilms' tumor gene 1 (WT1) protein.
Topics: Antimetabolites, Antineoplastic; Cell Line, Tumor; Cytarabine; Humans; Interferon Regulatory Factors; Leukemia; Up-Regulation; WT1 Proteins; Zinc Fingers | 2016 |
The novel HSP90 inhibitor NVP-AUY922 shows synergistic anti-leukemic activity with cytarabine in vivo.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cytarabine; Disease Models, Animal; Female; HSP90 Heat-Shock Proteins; Humans; Isoxazoles; Leukemia; Male; Neoplasm Proteins; Resorcinols; Signal Transduction | 2016 |
Safety of liposomal cytarabine CNS prophylaxis in children, adolescent and young adult hematopoietic stem cell transplant recipients with acute leukemia and non-Hodgkin lymphoma.
Topics: Acute Disease; Adolescent; Adult; Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Child; Cytarabine; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Liposomes; Lymphoma, Non-Hodgkin; Neoplasm Invasiveness; Treatment Outcome; Young Adult | 2016 |
AMD3100 and G-CSF disrupt the cross-talk between leukemia cells and the endosteal niche and enhance their sensitivity to chemotherapeutic drugs in biomimetic polystyrene scaffolds.
Topics: Antineoplastic Agents; Apoptosis; Benzylamines; Biomimetic Materials; Cell Adhesion; Cell Movement; Cells, Cultured; Chemokine CXCL12; Cyclams; Cytarabine; Granulocyte Colony-Stimulating Factor; Heterocyclic Compounds; Humans; Leukemia; Leukemia, Myeloid, Acute; Polystyrenes; Receptor Cross-Talk; Receptors, CXCR4; Stromal Cells | 2016 |
Fibroblast Growth Factor-2 facilitates the growth and chemo-resistance of leukemia cells in the bone marrow by modulating osteoblast functions.
Topics: Animals; Antineoplastic Agents; Bone Marrow Cells; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cytarabine; Drug Resistance, Neoplasm; Fibroblast Growth Factor 2; Humans; Imatinib Mesylate; Leukemia; Mice; Neoplasm Transplantation; Osteoblasts; Tumor Microenvironment | 2016 |
Ellison RR, Holland JF, Weil M, et al. Arabinosyl cytosine: a useful agent in the treatment of acute leukemia in adults. Blood. 1968;32(4):507-523.
Topics: Acute Disease; Adult; Antimetabolites, Antineoplastic; Cytarabine; History, 20th Century; Humans; Leukemia; Leukemia, Myeloid | 2016 |
Sugar-modified poly(propylene imine) dendrimers as drug delivery agents for cytarabine to overcome drug resistance.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Cell Line, Tumor; Cell Survival; Cytarabine; Dendrimers; Drug Delivery Systems; Drug Resistance, Neoplasm; Equilibrative Nucleoside Transporter 1; Humans; Leukemia; Leukocytes, Mononuclear; Maltose; Polypropylenes | 2016 |
Homoharringtonine combined with aclarubicin and cytarabine synergistically induces apoptosis in t(8;21) leukemia cells and triggers caspase-3-mediated cleavage of the AML1-ETO oncoprotein.
Topics: Aclarubicin; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Proliferation; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Core Binding Factor Alpha 2 Subunit; Cytarabine; Drug Synergism; Harringtonines; Homoharringtonine; Humans; Leukemia; Oncogene Proteins, Fusion; Proteolysis; RUNX1 Translocation Partner 1 Protein; Translocation, Genetic | 2016 |
ΔNp73 overexpression promotes resistance to apoptosis but does not cooperate with PML/RARA in the induction of an APL-leukemic phenotype.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Bone Marrow Transplantation; Cathepsin G; Cell Differentiation; Cell Proliferation; Cell Self Renewal; Cell Transformation, Neoplastic; Cells, Cultured; Cytarabine; Gene Expression Regulation, Leukemic; Genetic Predisposition to Disease; Leukemia; Mice, Inbred NOD; Mice, SCID; Mice, Transgenic; Neoplastic Stem Cells; Phenotype; Promyelocytic Leukemia Protein; Retinoic Acid Receptor alpha; Signal Transduction; Time Factors; Transfection; Tumor Protein p73; Up-Regulation | 2017 |
Psychosexual development and satisfaction in long-term survivors of childhood cancer: Neurotoxic treatment intensity as a risk indicator.
Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Case-Control Studies; Cranial Irradiation; Cytarabine; Female; Humans; Injections, Spinal; Leukemia; Lymphoma; Male; Methotrexate; Neoplasms; Neurotoxicity Syndromes; Orgasm; Personal Satisfaction; Psychosexual Development; Reproductive Health; Risk Factors; Sexual Partners; Surveys and Questionnaires; Survivors; Thiotepa; Young Adult | 2017 |
[Up-regulation of CD86 and cytokine expression in acute leukemia cells by Ara-C].
Topics: B7-2 Antigen; Cells, Cultured; Cytarabine; Cytokines; Gene Expression Regulation, Leukemic; Humans; Leukemia; Leukocytes, Mononuclear; Lymphocyte Activation; NF-kappa B; U937 Cells; Up-Regulation | 2008 |
Treatment of invasive aspergillosis with nonmyeloablative allogeneic stem cell transplantation: the hunter becomes the hunted.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Aspergillosis; Cytarabine; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Mitoxantrone; Transplantation Conditioning; Transplantation, Homologous | 2008 |
[Study on the relationship between human cytidine deaminase gene polymorphisms and Ara-C sensitivity].
Topics: Cytarabine; Cytidine Deaminase; Drug Resistance, Neoplasm; Humans; Leukemia; Polymorphism, Single Nucleotide | 2008 |
Resistance to cytarabine induces the up-regulation of NKG2D ligands and enhances natural killer cell lysis of leukemic cells.
Topics: Antimetabolites, Antineoplastic; Cell Line, Tumor; Cell Survival; Cytarabine; Drug Resistance; Drug Resistance, Neoplasm; Extracellular Signal-Regulated MAP Kinases; Humans; Interferon-gamma; Killer Cells, Natural; Leukemia; Ligands; NK Cell Lectin-Like Receptor Subfamily K; Phosphorylation; Up-Regulation | 2008 |
[Relationship between the expression of the genes encoding the key enzymes for cytarabine metabolism and the pharmacokinetics of cytarabine in the treatment of childhood acute leukemia with high-dose cytarabine].
Topics: Antimetabolites, Antineoplastic; Child; Cytarabine; Cytidine Deaminase; Deoxycytidine Kinase; Gene Expression; Humans; Leukemia; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2008 |
Treatment-subgroup interaction: an example from a published, phase II clinical trial.
Topics: Acute Disease; Adult; Amsacrine; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Bias; Clinical Trials, Phase II as Topic; Cytarabine; Humans; Leukemia; Patient Selection; Prednisone; Prognosis; Research Design; Treatment Outcome; Vincristine | 2009 |
Molecular targeting of MLL-rearranged leukemia cell lines with the synthetic peptide PFWT synergistically enhances the cytotoxic effect of established chemotherapeutic agents.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Cell Cycle; Cell Proliferation; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 4; Chromosomes, Human, Pair 9; Colony-Forming Units Assay; Cytarabine; DNA-Binding Proteins; Drug Synergism; Etoposide; Gene Rearrangement; Histone-Lysine N-Methyltransferase; Humans; Leukemia; Myeloid-Lymphoid Leukemia Protein; Necrosis; Nuclear Proteins; Peptide Fragments; Transcriptional Elongation Factors; Translocation, Genetic; Tumor Cells, Cultured | 2009 |
A LC-MS/MS method for the analysis of intracellular nucleoside triphosphate levels.
Topics: Antimetabolites, Antineoplastic; Bone Marrow Cells; Cell Line, Tumor; Chromatography, Liquid; Cytarabine; Humans; Leukemia; Leukemia, Myeloid, Acute; Linear Models; Nucleotides; Oligodeoxyribonucleotides; Sensitivity and Specificity; Tandem Mass Spectrometry | 2009 |
Sinusal bradycardia after receiving intermediate or high dose cytarabine: four cases from a single institution.
Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Bradycardia; Cytarabine; Female; Humans; Leukemia; Male; Treatment Outcome | 2009 |
A comparative study of outcomes of idarubicin- and etoposide-intensified conditioning regimens for allogeneic peripheral blood stem cell transplantation in patients with high-risk acute leukemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Aspergillus; Busulfan; China; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Disease-Free Survival; Etoposide; Female; Graft Survival; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Hydroxyurea; Idarubicin; Immunosuppressive Agents; Leukemia; Leukemia, Myeloid, Acute; Male; Methylprednisolone; Mucositis; Pneumonia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Premedication; Retrospective Studies; Risk Factors; Semustine; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Whole-Body Irradiation | 2009 |
Clofarabine-based salvage chemotherapy for relapsed or refractory acute leukemia before allogeneic stem cell transplantation: results from a case series.
Topics: Acute Disease; Adenine Nucleotides; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cyclophosphamide; Cytarabine; Drug Resistance, Neoplasm; Female; Humans; Leukemia; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Myelomonocytic, Acute; Male; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Salvage Therapy; Stem Cell Transplantation; Transplantation, Homologous; Treatment Outcome | 2009 |
Last exit clofarabine?
Topics: Acute Disease; Adenine Nucleotides; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cyclophosphamide; Cytarabine; Humans; Leukemia; Leukemia, Myeloid; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Salvage Therapy; Stem Cell Transplantation; Transplantation, Homologous; Treatment Outcome | 2009 |
The cytotoxic effects of gemtuzumab ozogamicin (mylotarg) in combination with conventional antileukemic agents by isobologram analysis in vitro.
Topics: Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Etoposide; Gemtuzumab; HL-60 Cells; Humans; Idarubicin; Immunotoxins; Leukemia; Mercaptopurine; Methotrexate; Mitoxantrone; Sialic Acid Binding Ig-like Lectin 3; U937 Cells; Vincristine | 2009 |
Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction.
Topics: Adenosine Triphosphate; Animals; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Biphenyl Compounds; Cell Proliferation; Cytarabine; Fatty Acid Synthases; Fatty Acids; Humans; Ion Channels; Leukemia; Mice; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mitochondrial Proteins; Nitrophenols; Oxidation-Reduction; Piperazines; Reactive Oxygen Species; Sulfonamides; Uncoupling Protein 2 | 2010 |
Celastrol and an EGCG pro-drug exhibit potent chemosensitizing activity in human leukemia cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Catechin; Cell Line, Tumor; Cytarabine; Daunorubicin; Fusion Proteins, bcr-abl; Humans; Leukemia; Molecular Structure; Pentacyclic Triterpenes; Plant Extracts; Prodrugs; Triterpenes | 2010 |
[The influence of Ara-C on anti-CD3/anti-Pgp mediating T-lymphocytes activities against multi-drug resistant leukemia cells.].
Topics: Cytarabine; Humans; K562 Cells; Leukemia; T-Lymphocytes | 2009 |
Clonogenic assays measure leukemia stem cell killing not detectable by chromium release and flow cytometric cytotoxicity assays.
Topics: ADP-ribosyl Cyclase 1; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Cell Culture Techniques; Cell Line, Tumor; Cell Separation; Chromium Isotopes; Cytarabine; Cytotoxicity Tests, Immunologic; Cytotoxicity, Immunologic; Daunorubicin; Flow Cytometry; Humans; Killer Cells, Natural; Leukemia; Neoplastic Stem Cells; Sensitivity and Specificity; Tumor Stem Cell Assay | 2010 |
[Successful selection of chemotherapy based on cell surface antigens in a patient with mixed phenotype acute leukemia].
Topics: Acute Disease; Antigens, Surface; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Daunorubicin; Humans; Leukemia; Male; Middle Aged; Prednisolone; Treatment Outcome; Vincristine | 2010 |
Induction of resistance to the lipophilic cytarabine prodrug elacytarabine (CP-4055) in CEM leukemic cells.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cytarabine; Cytidine Deaminase; Deoxycytidine; Drug Resistance, Neoplasm; Gemcitabine; Humans; Leukemia; Nucleoside Deaminases; Polymerase Chain Reaction | 2010 |
Leukaemia cutis at the site of striae distensae: an isotopic response?
Topics: Antineoplastic Combined Chemotherapy Protocols; Atrophy; Biopsy; Cytarabine; Female; Humans; Idarubicin; Leukemia; Middle Aged; Skin; Skin Diseases; Skin Neoplasms; Treatment Outcome | 2010 |
Novel second mitochondria-derived activator of caspases (Smac) mimetic compounds sensitize human leukemic cell lines to conventional chemotherapeutic drug-induced and death receptor-mediated apoptosis.
Topics: Antigens, CD34; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; Cytarabine; Drug Synergism; Etoposide; Humans; Inhibitor of Apoptosis Proteins; Intracellular Signaling Peptides and Proteins; Leukemia; Mitochondrial Proteins; Protein Binding; Stem Cells; TNF-Related Apoptosis-Inducing Ligand; X-Linked Inhibitor of Apoptosis Protein | 2011 |
The antiparasitic agent ivermectin induces chloride-dependent membrane hyperpolarization and cell death in leukemia cells.
Topics: Animals; Antineoplastic Agents; Antiparasitic Agents; Calcium; Cell Death; Cell Line, Tumor; Cell Membrane; Cell Size; Cell Survival; Chlorides; Cytarabine; Daunorubicin; Drug Synergism; Gene Expression Regulation, Leukemic; Humans; Ivermectin; Leukemia; Mice; Mice, SCID; Reactive Oxygen Species; Tumor Cells, Cultured | 2010 |
Negative regulatory effects of Mnk kinases in the generation of chemotherapy-induced antileukemic responses.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Line, Transformed; Cells, Cultured; Cytarabine; Drug Resistance, Neoplasm; Humans; K562 Cells; Leukemia; Mice; Protein Serine-Threonine Kinases; U937 Cells | 2010 |
Adhesion-induced drug resistance in leukemia stem cells.
Topics: Antineoplastic Agents; Bone Marrow Cells; Cell Adhesion; Cell Cycle; Cell Line, Tumor; Coculture Techniques; Cyclin-Dependent Kinase Inhibitor Proteins; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Etoposide; Humans; Leukemia; Lysosomes; Neoplastic Stem Cells; Osmolar Concentration; Proto-Oncogene Proteins c-bcl-2; Stem Cell Niche; Stromal Cells; Up-Regulation; Vacuolar Proton-Translocating ATPases | 2010 |
Synthesis and evaluation of fatty acyl ester derivatives of cytarabine as anti-leukemia agents.
Topics: Antimetabolites, Antineoplastic; Cell Proliferation; Cytarabine; Esters; Fatty Acids; Humans; Leukemia; Prodrugs; Tumor Cells, Cultured | 2010 |
Acute myeloid leukemia associated with t(10;17)(p13-15;q12-21) and phagocytic activity by leukemic blasts: a clinical study and review of the literature.
Topics: Adolescent; Adult; Antigens, CD; Antimetabolites, Antineoplastic; Blast Crisis; Child; Chromosome Mapping; Chromosomes, Human, Pair 10; Chromosomes, Human, Pair 17; Cytarabine; Daunorubicin; Female; Humans; Leukemia; Magnetic Resonance Imaging; Male; Middle Aged; Peroxidase; Phagocytes; Translocation, Genetic | 2010 |
[Successful treatment of high risk/refractory leukemia by tumor-ablative individualized conditioning allogeneic hematopoietic stem cell transplantation].
Topics: Cytarabine; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Transplantation Conditioning | 2010 |
Cell cycle-dependent priming action of granulocyte colony-stimulating factor (G-CSF) enhances in vitro apoptosis induction by cytarabine and etoposide in leukemia cell lines.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cytarabine; Etoposide; Flow Cytometry; Granulocyte Colony-Stimulating Factor; Humans; In Vitro Techniques; Leukemia | 2010 |
Intrathecal liposomal cytarabine (lipoCIT) administration in patients with leukemic or lymphomatous meningitis: efficacy and long-term safety in a single institution.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Cytarabine; Female; Humans; Injections, Spinal; Leukemia; Liposomes; Lymphoma; Male; Meningeal Neoplasms; Middle Aged; Retrospective Studies; Time Factors; Treatment Outcome; Young Adult | 2012 |
Characterization of cytarabine-resistant leukemic cell lines established from five different blood cell lineages using gene expression and proteomic analyses.
Topics: 5'-Nucleotidase; Antimetabolites, Antineoplastic; Cell Line, Tumor; Cell Lineage; Cell Survival; Cytarabine; Deoxycytidine Kinase; Drug Resistance, Neoplasm; Electrophoresis, Gel, Two-Dimensional; Enzyme Assays; Gene Expression Profiling; Genes, Neoplasm; Humans; Leukemia; Oligonucleotide Array Sequence Analysis; Proteome | 2011 |
Successful management with clofarabine for refractory leukaemia in a young adult with chronic renal failure.
Topics: Adenine Nucleotides; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cytarabine; Disease Management; Humans; Kidney Failure, Chronic; Leukemia; Male; Renal Dialysis; Salvage Therapy; Treatment Outcome; Young Adult | 2011 |
Insulin infusion to treat severe hypertriglyceridemia associated with pegaspargase therapy: a case report.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Cyclophosphamide; Cytarabine; Humans; Hypertriglyceridemia; Infusions, Intravenous; Insulin; Leukemia; Male; Mercaptopurine; Polyethylene Glycols | 2011 |
DNA mismatch repair status affects cellular response to Ara-C and other anti-leukemic nucleoside analogs.
Topics: Antimetabolites, Antineoplastic; Cytarabine; DNA Mismatch Repair; Humans; Leukemia; Nucleosides; Treatment Outcome | 2011 |
Retrospective analysis of risk factors for development of liver dysfunction in transient leukemia of Down syndrome.
Topics: Cytarabine; Disease Progression; Down Syndrome; Female; Hepatomegaly; Humans; Hyaluronic Acid; Immunosuppressive Agents; Infant; Infant, Newborn; Leukemia; Liver Cirrhosis; Liver Diseases; Male; Respiration Disorders; Retrospective Studies; Risk Factors; Splenomegaly | 2011 |
Long circulating PEGylated PLGA nanoparticles of cytarabine for targeting leukemia.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Cytarabine; Delayed-Action Preparations; Female; Humans; Lactic Acid; Leukemia; Male; Mice; Mice, Inbred BALB C; Nanoparticles; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley | 2011 |
Metabolism and accumulation of the lipophilic deoxynucleoside analogs elacytarabine and CP-4126.
Topics: Antineoplastic Agents; Cell Line; Cytarabine; Deoxycytidine; Deoxycytidine Kinase; Dipyridamole; Drug Resistance, Neoplasm; Gemcitabine; Humans; Leukemia; Nucleoside Transport Proteins; Nucleotidases | 2012 |
Development and evaluation of nanostructured lipid carriers of cytarabine for treatment of meningeal leukemia.
Topics: Calorimetry, Differential Scanning; Cytarabine; Drug Carriers; Humans; Leukemia; Lipids; Meningeal Neoplasms; Microscopy, Electron, Transmission; Nanostructures; Particle Size; Powder Diffraction | 2011 |
Combination effects of digalloylresveratrol with arabinofuranosylcytosine and difluorodeoxycytidine in human leukemia and pancreatic cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Proliferation; Cytarabine; Deoxycytidine; Gallic Acid; Gemcitabine; HL-60 Cells; Humans; Leukemia; Pancreatic Neoplasms; Stilbenes; Tumor Stem Cell Assay | 2011 |
Comparison of total body irradiation before and after chemotherapy in pretreatment for hematopoietic stem cell transplantation.
Topics: Adolescent; Adult; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Protocols; Child; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Female; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Lymphoma; Male; Middle Aged; Radiotherapy Dosage; Retrospective Studies; Transplantation Conditioning; Whole-Body Irradiation; Young Adult | 2012 |
Cytosine arabinoside potentiates the apoptotic effect of bendamustine on several B- and T-cell leukemia/lymphoma cells and cell lines.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Bendamustine Hydrochloride; Cell Cycle; Cell Line, Tumor; Cytarabine; Humans; Leukemia; Leukemia, B-Cell; Leukemia, T-Cell; Lymphoma; Lymphoma, B-Cell; Lymphoma, T-Cell; Nitrogen Mustard Compounds | 2012 |
Nature and dynamics of nucleosome release from neoplastic and non-neoplastic cells.
Topics: Apoptosis; Blast Crisis; Cytarabine; Etoposide; Hep G2 Cells; Humans; L-Lactate Dehydrogenase; Leukemia; Neoplasms; Neutrophils; Nucleosomes; Tetradecanoylphorbol Acetate; TNF-Related Apoptosis-Inducing Ligand | 2012 |
Self-assembled squalenoyl-cytarabine nanostructures as a potent nanomedicine for treatment of leukemic diseases.
Topics: Analysis of Variance; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Cytarabine; Humans; Leukemia; Liver; Mice; Nanomedicine; Nanoparticles; Particle Size; Spleen; Squalene; Survival Analysis; Tissue Distribution; Xenograft Model Antitumor Assays | 2012 |
PDCD2 knockdown inhibits erythroid but not megakaryocytic lineage differentiation of human hematopoietic stem/progenitor cells.
Topics: Antigens, CD34; Apoptosis Regulatory Proteins; Bone Marrow Cells; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cytarabine; Erythroid Cells; Gene Expression; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Gene Knockdown Techniques; Genetic Vectors; Hematopoiesis; Hematopoietic Stem Cells; Humans; K562 Cells; Lentivirus; Leukemia; Megakaryocytes; RNA Interference; Transduction, Genetic | 2012 |
Chemotherapeutic treatment for leukemia in a bearded dragon (Pogona vitticeps).
Topics: Animals; Antineoplastic Agents; Cytarabine; Fatal Outcome; Leukemia; Lizards; Male | 2011 |
[Lesions in the nervous system during chemotherapy of acute leukosis and non-Hodgkin lymphomas].
Topics: Acute Disease; Adult; Aged; Antineoplastic Agents; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Prednisolone; Vincristine | 2012 |
Synthesis of cytarabine lipid drug conjugate for treatment of meningeal leukemia: development, characterization and in vitro cell line studies.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cytarabine; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; In Vitro Techniques; Leukemia; Lipids; Meningeal Neoplasms; Mice; Models, Chemical; Particle Size; Polysorbates; Stearic Acids | 2012 |
[Studies on concentrations and interactions of drugs in patients with administration of high-dose of cytosine arabinoside and methotrexate].
Topics: Adolescent; Adult; Cytarabine; Drug Interactions; Female; Humans; Instillation, Drug; Leukemia; Male; Methotrexate; Middle Aged; Young Adult | 2012 |
[Progress in the field of hematology in the last 100 years: Medical history of acute leukemia].
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; History, 20th Century; Humans; Japan; Leukemia; Mercaptopurine; Prednisolone; Vincristine | 2002 |
Schedule-dependent synergism and antagonism between methotrexate and cytarabine against human leukemia cell lines in vitro.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Leukemia; Methotrexate; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2002 |
Daunorubicin- and Ara-C-induced interphasic apoptosis of human type II leukemia cells is caspase-8-independent.
Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Carrier Proteins; Caspase 8; Caspase 9; Caspases; Ceramides; Cytarabine; Daunorubicin; DNA Damage; Fas-Associated Death Domain Protein; Humans; Interphase; Jurkat Cells; Leukemia; Mutation; Time Factors; Tumor Cells, Cultured | 2002 |
[Bcl-2 antisense oligodeoxynucleotide enhances araninosyl cytosine-induced apoptosis of primary leukemia cells].
Topics: Antimetabolites, Antineoplastic; Apoptosis; Cytarabine; Drug Interactions; HL-60 Cells; Humans; K562 Cells; Leukemia; Oligodeoxyribonucleotides, Antisense; Proto-Oncogene Proteins c-bcl-2 | 2002 |
Structural impact of the leukemia drug 1-beta-D-arabinofuranosylcytosine (Ara-C) on the covalent human topoisomerase I-DNA complex.
Topics: Antimetabolites, Antineoplastic; Binding Sites; Crystallography; Cytarabine; DNA; DNA Topoisomerases, Type I; Enzyme Induction; Humans; Leukemia; Protein Structure, Tertiary | 2003 |
The effect of the Fas/FasL pathway during chemotherapeutic drug-induced apoptosis of leukaemeic cells.
Topics: Apoptosis; Cytarabine; Daunorubicin; Fas Ligand Protein; fas Receptor; HL-60 Cells; Humans; K562 Cells; Leukemia; Membrane Glycoproteins; U937 Cells | 2001 |
A functional single-nucleotide polymorphism in the human cytidine deaminase gene contributing to ara-C sensitivity.
Topics: Child, Preschool; Cytarabine; Cytidine Deaminase; Deamination; DNA, Complementary; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Leukemia; Microbial Sensitivity Tests; Polymorphism, Single Nucleotide; Recombinant Proteins; Saccharomyces cerevisiae; Sequence Alignment | 2003 |
Inactivation of deoxycytidine kinase and overexpression of P-glycoprotein in AraC and daunorubicin double resistant leukemic cell lines.
Topics: 2-Chloroadenosine; Alternative Splicing; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azacitidine; Biological Transport; Buthionine Sulfoximine; Calcium Channel Blockers; Cytarabine; Daunorubicin; Decitabine; Deoxyadenosines; Deoxycytidine Kinase; DNA Mutational Analysis; DNA, Neoplasm; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Glutathione; Humans; Idarubicin; Leukemia; Methotrexate; Neoplasm Proteins; Rats; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured; Verapamil | 2003 |
Donor T-lymphocyte infusion for unrelated allogeneic bone marrow transplantation with CD3+ T-cell-depleted graft.
Topics: Adolescent; Adult; Antigens, CD; Bone Marrow Transplantation; CD3 Complex; Cyclophosphamide; Cytarabine; Female; Graft vs Host Disease; Humans; Leukemia; Lymphocyte Depletion; Lymphocyte Transfusion; Lymphoma, Non-Hodgkin; Male; Middle Aged; Probability; Retrospective Studies; Survival Analysis; T-Lymphocytes; Time Factors; Transplantation Conditioning; Transplantation, Homologous; Whole-Body Irradiation | 2003 |
[Design of antisense oligodeoxynucleotide targeting at bcl-2 mRNA and observation on its effect on the sensitivity of leukemia cells to arabinosyl cytosine].
Topics: Antimetabolites, Antineoplastic; Apoptosis; Base Sequence; Cell Division; Cell Survival; Cytarabine; Drug Design; Drug Synergism; HL-60 Cells; Humans; Inhibitory Concentration 50; K562 Cells; Leukemia; Molecular Sequence Data; Nucleic Acid Conformation; Oligonucleotides, Antisense; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger | 2003 |
Molecular cytogenetic characterization of drug-resistant leukemia cell lines by comparative genomic hybridization and fluorescence in situ hybridization.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Blotting, Western; Cell Nucleus; Chromosome Mapping; Cytarabine; Doxorubicin; Drug Resistance, Neoplasm; Humans; In Situ Hybridization, Fluorescence; Inhibitory Concentration 50; Leukemia; Multidrug Resistance-Associated Proteins; Nucleic Acid Hybridization; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured; Vincristine | 2002 |
Enforced expression of the tumor suppressor p53 renders human leukemia cells (U937) more sensitive to 1-[beta-D-arabinofuranosyl]cytosine (ara-C)-induced apoptosis.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Arabinofuranosylcytosine Triphosphate; Cytarabine; Genes, p53; Genes, Tumor Suppressor; Humans; Leukemia; U937 Cells | 2003 |
Stem cell transplantation after salvage therapy with high-dose cytarabine and amsacrine in adults with high-risk leukaemia.
Topics: Adolescent; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Male; Middle Aged; Retrospective Studies; Salvage Therapy; Survival Analysis; Treatment Outcome | 2003 |
[The therapeutic effects of FLAG regime for refractory and relapsing acute leukemia].
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia; Male; Middle Aged; Recurrence; Vidarabine | 2003 |
Interaction between leukemic-cell VLA-4 and stromal fibronectin is a decisive factor for minimal residual disease of acute myelogenous leukemia.
Topics: Animals; Antibodies; Antimetabolites, Antineoplastic; Cytarabine; Drug Resistance, Neoplasm; Fibronectins; Humans; Integrin alpha4beta1; Integrin alpha5beta1; Leukemia; Leukemia, Myeloid, Acute; Mice; Mice, SCID; Neoplasm, Residual; Phosphatidylinositol 3-Kinases; Predictive Value of Tests; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Stromal Cells; Survival Rate; Time Factors; Tumor Cells, Cultured | 2003 |
Risk of acute leukemia following epirubicin-based adjuvant chemotherapy: a report from the National Cancer Institute of Canada Clinical Trials Group.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Cytarabine; Epirubicin; Female; Fluorouracil; Humans; Leukemia; Methotrexate; Middle Aged; Neoplasms, Multiple Primary; Risk | 2003 |
HA14-1 selectively induces apoptosis in Bcl-2-overexpressing leukemia/lymphoma cells, and enhances cytarabine-induced cell death.
Topics: Apoptosis; Benzopyrans; Blast Crisis; Bone Marrow Cells; Cell Death; Cell Survival; Cytarabine; Drug Synergism; Enzyme Inhibitors; Genes, bcl-2; Hematopoietic Stem Cells; Humans; Leukemia; Lymphoma; Nitriles; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured | 2003 |
[Allergic reaction against an emulsifier, HCO-60, contained in multamin and enocitabine].
Topics: Acute Disease; Antineoplastic Agents; Castor Oil; Cytarabine; Drug Hypersensitivity; Female; Humans; Leukemia; Middle Aged; Surface-Active Agents; Urticaria; Vitamins | 2003 |
Complete remission in advanced blastic NK-cell lymphoma/leukemia in elderly patients using the hyper-CVAD regimen.
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Humans; Killer Cells, Natural; Leukemia; Lymphoma, T-Cell; Male; Methotrexate; Middle Aged; Remission Induction; Vincristine | 2003 |
SYNERGISM OF THE ANTINEOPLASTIC ACTIVITY OF CYTOSINE ARABINOSIDE BY PORFIROMYCIN.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Body Weight; Cytarabine; Cytosine; Leukemia; Leukemia L1210; Leukemia, Experimental; Mice; Mitomycin; Mitomycins; Neoplasms; Neoplasms, Experimental; Nucleosides; Pharmacology; Porfiromycin; Research; Survival | 1964 |
THE REVERSAL OF CYTOSINE ARABINOSIDE ACTIVITY IN VIVO BY DEOXYCYTIDINE.
Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cytarabine; Cytosine; Deoxycytidine; Leukemia; Leukemia, Experimental; Neoplasms; Neoplasms, Experimental; Nucleosides; Pharmacology; Research; Sarcoma 180 | 1964 |
COMPARATIVE STUDIES OF LEUKEMIC CELLS SENSITIVE AND RESISTANT TO CYTOSINE ARABINOSIDE.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Chromatography; Cytarabine; Cytosine; DNA; DNA, Neoplasm; Leukemia; Leukemia, Experimental; Magnesium; Neoplasms; Nucleosides; Pharmacology; Phosphotransferases; Research; RNA; RNA, Neoplasm; Tissue Culture Techniques | 1965 |
[Synergistic effect of Apo2L and chemotherapeutic agents on leukemia cells].
Topics: Antineoplastic Agents; Apoptosis Regulatory Proteins; Cytarabine; Drug Synergism; Etoposide; Female; HL-60 Cells; Humans; Leukemia; Male; Membrane Glycoproteins; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha | 2003 |
The role of cytidine deaminase and GATA1 mutations in the increased cytosine arabinoside sensitivity of Down syndrome myeloblasts and leukemia cell lines.
Topics: Base Sequence; Cell Death; Cell Line, Tumor; Cells, Cultured; Cytarabine; Cytosine Deaminase; DNA Primers; DNA-Binding Proteins; Down Syndrome; Erythroid-Specific DNA-Binding Factors; Exons; GATA1 Transcription Factor; Humans; Introns; Leukemia; Molecular Sequence Data; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factors; Transcription, Genetic | 2004 |
Antiproliferative efficacy of the third-generation bisphosphonate, zoledronic acid, combined with other anticancer drugs in leukemic cell lines.
Topics: Antineoplastic Agents; Benzamides; Cell Death; Cell Division; Cell Line, Tumor; Cytarabine; Daunorubicin; Diphosphonates; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Hydroxyurea; Imatinib Mesylate; Imidazoles; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Methotrexate; Piperazines; Pyrimidines; Vincristine; Zoledronic Acid | 2004 |
The neuropeptides vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase activating polypeptide (PACAP) modulate several biochemical pathways in human leukemic myeloid cells.
Topics: Adenosine Triphosphate; Bromodeoxyuridine; Calcium; Cell Line, Tumor; Cyclic AMP; Cytarabine; Cytosol; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Interactions; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Estrenes; Flow Cytometry; Glycophorins; Humans; Immunosuppressive Agents; Inositol Phosphates; Intercellular Adhesion Molecule-1; Leukemia; Myeloid Cells; Neuropeptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Protein Binding; Proto-Oncogene Proteins; Pyrrolidinones; Receptors, Vasoactive Intestinal Peptide; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Thrombin; Time Factors; Transcription Factor AP-1; Vasoactive Intestinal Peptide | 2004 |
Antiproliferative activity and mechanism of action of fatty acid derivatives of arabinofuranosylcytosine in leukemia and solid tumor cell lines.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cytarabine; Cytidine Deaminase; DNA; Drug Screening Assays, Antitumor; Fatty Acids; Humans; Leukemia; Nucleoside Deaminases; Rats; RNA | 2004 |
Tailored therapy of adult acute leukaemia in Jehovah's Witnesses: unjustified reluctance to treat.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Case Management; Cytarabine; Daunorubicin; Etoposide; Female; Hemoglobins; Hemorrhage; Humans; Jehovah's Witnesses; Leukemia; Male; Middle Aged; Multiple Organ Failure; Patient Acceptance of Health Care; Refusal to Treat; Remission Induction; Tretinoin; Vincristine | 2004 |
Novel 2'-substituted, 3'-deoxy-phosphatidyl-myo-inositol analogues reduce drug resistance in human leukaemia cell lines with an activated phosphoinositide 3-kinase/Akt pathway.
Topics: Antineoplastic Agents; Apoptosis; Cell Survival; Cytarabine; Down-Regulation; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Humans; Leukemia; Neoplasm Proteins; Phosphatidylinositol 3-Kinases; Phosphatidylinositols; Phosphoinositide-3 Kinase Inhibitors; Phospholipid Ethers; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Tumor Cells, Cultured | 2004 |
Susceptibility to cytosine arabinoside (Ara-C)-induced cytotoxicity in human leukemia cell lines.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Cell Line, Tumor; Cell Nucleus; Cytarabine; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Genes, p53; Humans; Leukemia; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Suppressor Protein p53 | 2004 |
Synergistic effect of SU11248 with cytarabine or daunorubicin on FLT3 ITD-positive leukemic cells.
Topics: Antineoplastic Agents; Cell Division; Cell Line; Cell Line, Tumor; Cytarabine; Daunorubicin; Drug Synergism; Humans; Indoles; Intracellular Signaling Peptides and Proteins; Leukemia; Pyrroles; Sunitinib; Zinc Fingers | 2004 |
[Damage of vascular endothelium in the treatment of acute leukemia: in vitro study].
Topics: Acute Disease; Antineoplastic Agents; Cell Survival; Cells, Cultured; Culture Media; Cytarabine; Daunorubicin; Endothelial Cells; Endothelium, Vascular; Flow Cytometry; Humans; Immunohistochemistry; Leukemia; Models, Biological; Time Factors; Umbilical Veins | 2004 |
Fludarabine, cytosine arabinoside, granulocyte-colony stimulating factor with or without idarubicin in the treatment of high risk acute leukaemia or myelodysplastic syndromes.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia; Myelodysplastic Syndromes; Vidarabine | 2004 |
Immunocytochemical detection of deoxycytidine kinase in pediatric malignancies in relation to in vitro cytarabine sensitivity.
Topics: Antimetabolites, Antineoplastic; Brain; Brain Neoplasms; Cell Line, Tumor; Coloring Agents; Cytarabine; Deoxycytidine Kinase; Drug Resistance, Neoplasm; Humans; Immunohistochemistry; Leukemia; Neoplasms; Retinoblastoma; Tetrazolium Salts; Thiazoles | 2004 |
Antiproliferative activity and mechanism of action of fatty acid derivatives of arabinosylcytosine (ara-C) in leukemia and solid tumor cell lines.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Cell Proliferation; Cytarabine; Deoxycytidine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Fatty Acids; Gemcitabine; Humans; Inhibitory Concentration 50; Leukemia; Mice; Neoplasms; Rats; Time Factors | 2004 |
Gene-expression profiling reveals down-regulation of equilibrative nucleoside transporter 1 (ENT1) in Ara-C-resistant CCRF-CEM-derived cells.
Topics: Adenosine Deaminase; Caspase 3; Caspases; Cell Cycle Proteins; Cell Differentiation; Cell Line, Tumor; Cell Separation; Cytarabine; Down-Regulation; Drug Resistance, Neoplasm; Equilibrative Nucleoside Transporter 1; Gene Expression Profiling; Humans; Leukemia; Phosphorylation; Time Factors | 2004 |
[Sensitivity of survivin-positive primary leukemia cells to chemotherapy].
Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Antineoplastic Agents; Cell Survival; Cytarabine; Drug Screening Assays, Antitumor; Female; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Apoptosis Proteins; Leukemia; Male; Microtubule-Associated Proteins; Middle Aged; Neoplasm Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Survivin; Tumor Cells, Cultured | 2005 |
Knee arthritis as a rare inaugural manifestation of adult leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Arthritis; Cytarabine; Diagnosis, Differential; Dose-Response Relationship, Drug; Etoposide; Humans; Knee Joint; Leukemia; Magnetic Resonance Imaging; Male; Mitoxantrone; Radiography; Remission Induction; Treatment Outcome | 2005 |
Deguelin, A PI3K/AKT inhibitor, enhances chemosensitivity of leukaemia cells with an active PI3K/AKT pathway.
Topics: Acute Disease; Antigens, CD34; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cells, Cultured; Cytarabine; Drug Resistance, Neoplasm; Erythropoietin; Etoposide; HL-60 Cells; Humans; Leukemia; Leukemia, Myeloid; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Rotenone; Signal Transduction; Stem Cell Factor; Stem Cells | 2005 |
A sensitive new method for clinically monitoring cytarabine concentrations at the DNA level in leukemic cells.
Topics: Aged; Antimetabolites, Antineoplastic; Cytarabine; DNA, Neoplasm; Drug Monitoring; Female; HL-60 Cells; Humans; Leukemia; Male; Middle Aged; Sensitivity and Specificity; Tumor Cells, Cultured | 2005 |
Highly active antiretroviral therapy and outcome of AIDS-related Burkitt's lymphoma or leukemia. Results of the PETHEMA-LAL3/97 study.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Antiretroviral Therapy, Highly Active; Cyclophosphamide; Cytarabine; Dexamethasone; Disease-Free Survival; Etoposide; Female; Follow-Up Studies; Humans; Ifosfamide; Leucovorin; Leukemia; Lymphoma, AIDS-Related; Male; Methotrexate; Middle Aged; Prednisone; Treatment Outcome; Vincristine | 2005 |
Effect of notch ligands on in vitro sensitivity to chemo-therapeutic drugs in leukemia and lymphoma cells.
Topics: Antineoplastic Agents; Calcium-Binding Proteins; Caspase 3; Caspases; Cell Line, Tumor; Cell Proliferation; Cytarabine; Dexamethasone; Dose-Response Relationship, Drug; Doxorubicin; Enzyme Activation; Humans; Immunoblotting; Intercellular Signaling Peptides and Proteins; Intracellular Signaling Peptides and Proteins; Jagged-1 Protein; Leukemia; Ligands; Lymphoma; Membrane Proteins; Mitoxantrone; NF-kappa B; Phosphorylation; Poly(ADP-ribose) Polymerases; Receptors, Notch; Recombinant Proteins; Serrate-Jagged Proteins; U937 Cells | 2005 |
Usefulness of PKH fluorescent labelling to study leukemic cell proliferation with various cytostatic drugs or acetyl tetrapeptide--AcSDKP.
Topics: Amsacrine; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Bromodeoxyuridine; Cell Proliferation; Cytarabine; Daunorubicin; DNA; Etoposide; Flow Cytometry; Fluorescent Dyes; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hydrocarbons, Chlorinated; Leukemia; Leukemia, Myeloid, Acute; Microscopy, Fluorescence; Oligopeptides; Organic Chemicals; Radiation-Protective Agents | 2005 |
Synergistic effect of targeting mTOR by rapamycin and depleting ATP by inhibition of glycolysis in lymphoma and leukemia cells.
Topics: Adenosine Triphosphate; Apoptosis; Cell Proliferation; Cytarabine; Drug Synergism; Energy Metabolism; Glycolysis; Humans; Leukemia; Lymphoma; Protein Kinases; Sirolimus; TOR Serine-Threonine Kinases; Tumor Cells, Cultured | 2005 |
Mitoxantrone and cytosine arabinoside (ARA-C) in adult acute leukemia: an interim report.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Clinical Trials as Topic; Cytarabine; Drug Administration Schedule; Humans; Infusions, Intravenous; Leukemia; Leukemia, Myeloid, Acute; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome | 1989 |
In vitro sensitivity and cross-resistance to deoxynucleoside analogs in childhood acute leukemia.
Topics: Acute Disease; Child; Cytarabine; Drug Resistance, Multiple; Drug Screening Assays, Antitumor; Humans; Leukemia; Nucleosides | 2006 |
Cytotoxic effects of histone deacetylase inhibitor FK228 (depsipeptide, formally named FR901228) in combination with conventional anti-leukemia/lymphoma agents against human leukemia/lymphoma cell lines.
Topics: Antineoplastic Agents; Apoptosis; Benzamides; Camptothecin; Carboplatin; Cell Line, Tumor; Cell Survival; Cyclophosphamide; Cytarabine; Depsipeptides; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Etoposide; Histone Deacetylase Inhibitors; HL-60 Cells; Humans; Imatinib Mesylate; Irinotecan; K562 Cells; Leukemia; Lymphoma; Mercaptopurine; Piperazines; Pyrimidines; Time Factors | 2007 |
American Society of Clinical Oncology--42nd annual meeting. Poster presentations on leukemia and cytotoxic chemotherapy. 2-6 June 2006, Atlanta, GA, USA.
Topics: Clinical Trials as Topic; Cytarabine; Drug Combinations; Gossypol; Humans; Leukemia; Mastocytosis, Systemic; Molecular Structure; Pyrimidines; Pyrrolidines; Thionucleotides; Thymine; Trifluridine; Uracil | 2006 |
Zygomycosis in the immunocompromised patient: a case report.
Topics: Absidia; Acute Disease; Aerosols; Amphotericin B; Amsacrine; Antibiotic Prophylaxis; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Daunorubicin; Debridement; Drug Resistance, Fungal; Drug Resistance, Neoplasm; Etoposide; Fluconazole; Humans; Immunocompromised Host; Leukemia; Liposomes; Middle Aged; Mucormycosis; Sinusitis; Tomography, X-Ray Computed | 2006 |
Arsenic trioxide-responsive leukemia cutis in a patient with acute promyelocytic leukemia after ATRA treatment.
Topics: Adolescent; Anthracyclines; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Cytarabine; Female; Humans; Leukemia; Leukemia, Promyelocytic, Acute; Oxides; Risk; Skin; Tretinoin | 2006 |
Characterization of resistance to cytosine arabinoside (Ara-C) in NALM-6 human B leukemia cells.
Topics: Cell Line, Tumor; Cell Survival; Cytarabine; Cytidine Deaminase; Cytoprotection; Deoxycytidine Kinase; Dipyridamole; Drug Resistance, Neoplasm; Gene Expression; Humans; Leukemia; RNA, Messenger; Thioinosine | 2007 |
Synergistic antileukemia effect of genistein and chemotherapy in mouse xenograft model and potential mechanism through MAPK signaling.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cytarabine; Drug Synergism; Gene Expression Regulation, Neoplastic; Genistein; Humans; Leukemia; MAP Kinase Signaling System; Mice; Mice, SCID; Neoplasms, Experimental; Survival Rate; Transplantation, Heterologous; Tumor Burden | 2007 |
Antileukemic activity of sulfonamide conjugates of arabinosylcytosine.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Cell Proliferation; Cytarabine; Female; Leukemia; Male; Mice; Sulfonamides | 2006 |
Divergent cytotoxic effects of PKC412 in combination with conventional antileukemic agents in FLT3 mutation-positive versus -negative leukemia cell lines.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Cell Line, Tumor; Cytarabine; Doxorubicin; Etoposide; fms-Like Tyrosine Kinase 3; Humans; Idarubicin; Leukemia; Methotrexate; Mitoxantrone; Mutation; Protein Kinase C; Staurosporine | 2007 |
Anti-Cripto Mab inhibit tumour growth and overcome MDR in a human leukaemia MDR cell line by inhibition of Akt and activation of JNK/SAPK and bad death pathways.
Topics: Animals; Antibodies, Monoclonal; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; bcl-Associated Death Protein; bcl-X Protein; Caspase 9; Cell Growth Processes; Cell Line, Tumor; Cytarabine; Daunorubicin; Drug Synergism; Enzyme Activation; Epirubicin; Female; Humans; Intercellular Signaling Peptides and Proteins; Leukemia; MAP Kinase Kinase 4; Mice; Mice, SCID; Mitogen-Activated Protein Kinases; Oncogene Protein v-akt; Proto-Oncogene Proteins c-bcl-2 | 2007 |
Expression of multidrug resistance (MDR) proteins and in vitro drug resistance in acute leukemias.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Cell Survival; Child; Child, Preschool; Coloring Agents; Cytarabine; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Infant; Inhibitory Concentration 50; Leukemia; Leukemia, Myeloid; Male; Methylphenazonium Methosulfate; Middle Aged; Neoplasm Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Staining and Labeling; Tetrazolium Salts; Thiazoles; Treatment Outcome; Tumor Cells, Cultured | 2007 |
CODOX-M/IVAC (NCI 89-C-41) in children and adolescents with Burkitt's leukemia/lymphoma and large B-cell lymphomas: a 15-year monocentric experience.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Female; Humans; Ifosfamide; Leukemia; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Risk Factors; Survival Rate; Treatment Outcome; Vincristine | 2007 |
Biphenotypic acute leukaemia: a case series.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Female; Humans; Immunophenotyping; Leukemia; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome; Vincristine | 2007 |
A novel FLT3 inhibitor FI-700 selectively suppresses the growth of leukemia cells with FLT3 mutations.
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Blotting, Western; Cell Proliferation; Cytarabine; Drug Therapy, Combination; Enzyme Inhibitors; fms-Like Tyrosine Kinase 3; Humans; Leukemia; Mice; Mice, Inbred C3H; Mice, SCID; Mutation; Pyridines; Pyrimidines; Signal Transduction; STAT5 Transcription Factor; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2007 |
Toward optimal use of intrathecal liposomal cytarabine.
Topics: Brain Neoplasms; Cytarabine; Humans; Injections, Spinal; Leukemia; Liposomes | 2007 |
Resistance to Ara-C up-regulates the activation of NF-kappaB, telomerase activity and Fas expression in NALM-6 cells.
Topics: Antimetabolites, Antineoplastic; Apoptosis; bcl-2-Associated X Protein; BH3 Interacting Domain Death Agonist Protein; Cell Line, Tumor; Cytarabine; Drug Resistance, Neoplasm; fas Receptor; Formazans; Humans; Leukemia; NF-kappa B; Telomerase; Tetrazolium Salts; Tumor Suppressor Protein p53; Up-Regulation | 2007 |
Preclinical toxicology (subacute and acute) and efficacy of a new squalenoyl gemcitabine anticancer nanomedicine.
Topics: Animals; Antineoplastic Agents; Cytarabine; Deoxycytidine; Drug Evaluation, Preclinical; Gemcitabine; Leukemia; Mice; Mice, Inbred DBA; Nanomedicine; Nanostructures; Squalene; Treatment Outcome | 2008 |
Anti proliferative activity of ELACY (CP-4055) in combination with cloretazine (VNP40101M), idarubicin, gemcitabine, irinotecan and topotecan in human leukemia and lymphoma cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell Line, Tumor; Cytarabine; Deoxycytidine; Drug Interactions; Drug Screening Assays, Antitumor; Gemcitabine; Humans; Hydrazines; Idarubicin; Irinotecan; Leukemia; Lymphoma; Sulfonamides; Topotecan | 2008 |
Fludarabine/intermediate-dose cytarabine with or without allogeneic hematopoietic stem cell transplantation in poor-risk leukemia: a single center experience.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Male; Middle Aged; Recurrence; Risk Factors; Survival Rate; Transplantation, Homologous; Vidarabine | 2008 |
[The assay of intracelluar cytidine deaminase activity and its clinical significance in patient with acute leukemia].
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Cytarabine; Cytidine Deaminase; Drug Resistance, Neoplasm; Female; Humans; Intracellular Fluid; Leukemia; Male; Middle Aged; Young Adult | 2008 |
Reduced efficacy of topical corticosteroid in preventing cytarabine-induced kerato-conjunctivitis in patients receiving high-dose cytarabine and total body irradiation for allogeneic hematopoietic stem cell transplantation.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Cytarabine; Female; Hematopoietic Stem Cell Transplantation; Humans; Keratoconjunctivitis; Leukemia; Male; Middle Aged; Myelodysplastic Syndromes; Transplantation Conditioning; Transplantation, Homologous; Whole-Body Irradiation | 2008 |
Inhibition of in vitro lymphocyte transformation during chemotherapy in man.
Topics: Anemia, Hemolytic; Culture Techniques; Cyclophosphamide; Cytarabine; Humans; Immune Tolerance; Lectins; Leukemia; Lymphocytes; Mercaptopurine; Methotrexate; Neoplasms; Prednisolone; Smallpox Vaccine; Uveitis; Vincristine | 1967 |
Studies of 6-N-hydroxylamino-9-beta-D-ribofuranosylpurine in mouse leukemia.
Topics: Adenine; Animals; Body Weight; Cytarabine; Drug Antagonism; Drug Synergism; Fluorouracil; Guanine; Leukemia; Leukemia L1210; Mercaptopurine; Methotrexate; Mice; Nucleosides; Phosphotransferases; Purines; Vincristine | 1967 |
Clinical pharmacology and human antitumor activity of cytosine arabinoside.
Topics: Adenocarcinoma; Blood Platelets; Carcinoma, Squamous Cell; Cytarabine; Hemoglobinometry; Humans; Leukemia; Leukocyte Count; Lymphoma; Lymphoma, Non-Hodgkin | 1967 |
Acute leukemia treatment.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Child; Cytarabine; Humans; Leukemia; Mercaptopurine; Methotrexate; Prednisone; Vincristine | 1967 |
Informal discussion: experimental basis for the chemical eradication of leukemia.
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Cytarabine; Drug Antagonism; Drug Synergism; Humans; Leukemia; Liver; Methotrexate; Mice; Nitroso Compounds; Urea | 1967 |
The"real stuff" for intrathecal injection during leukaemia therapy.
Topics: Cerebrospinal Fluid; Cytarabine; Humans; Injections, Spinal; Leukemia; Meningeal Neoplasms; Methotrexate | 1982 |
Treatment of acute non-lymphoblastic leukaemia in elderly patients.
Topics: Acute Disease; Aged; Cytarabine; Humans; Leukemia | 1984 |
[Immunotherapy of acute blastic leukemia in adults].
Topics: Acute Disease; Adult; BCG Vaccine; Cytarabine; Doxorubicin; Hematopoietic Stem Cells; Humans; Immunotherapy; Leukemia; Thioguanine | 1981 |
[Inhibition of DNA synthesis in peripheral leukemic cells by cytosine-arabinoside; attempt at deriving therapeutic application].
Topics: Cell Division; Cytarabine; Depression, Chemical; DNA, Neoplasm; Humans; Leukemia; Leukocytes; Prognosis | 1981 |
Phase I study on 5-aza-2'-deoxycytidine in children with acute leukemia.
Topics: Acute Disease; Adolescent; Antineoplastic Agents; Azacitidine; Child; Child, Preschool; Cytarabine; Decitabine; Dose-Response Relationship, Drug; Drug Evaluation; Hematopoietic System; Humans; Leukemia; Male | 1981 |
[A case of hypoplastic leukemia in advanced age induced into complete remission with continuous drip infusion of cyclocytidine and prednisolone (author's transl)].
Topics: Ancitabine; Bone Marrow; Cytarabine; Drug Therapy, Combination; Female; Humans; Infusions, Parenteral; Leukemia; Middle Aged; Prednisolone | 1982 |
Combination chemotherapy with amsacrine (AMSA) and cyclocytidine in refractory childhood leukemia: preliminary observations of a phase II study.
Topics: Adolescent; Aminoacridines; Amsacrine; Ancitabine; Antineoplastic Agents; Child; Child, Preschool; Cytarabine; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Male; Retrospective Studies | 1983 |
[Comparative evaluation of combined chemotherapeutic regimens in acute non-lymphocytic leukemia].
Topics: Aclarubicin; Acute Disease; Adult; Age Factors; Ancitabine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Mercaptopurine; Middle Aged; Naphthacenes; Prednisolone | 1983 |
Results of intrathecal prophylaxis and treatment of CNS involvement in adult acute leukaemias.
Topics: Acute Disease; Brain Neoplasms; Cytarabine; Drug Administration Schedule; Humans; Injections, Spinal; Leukemia; Methotrexate; Prednisolone | 1984 |
[Initial results in allo- and auto-bone marrow transplantation in acute leukemia in East Germany].
Topics: Acute Disease; Adolescent; Adult; Body Weight; Bone Marrow Transplantation; Combined Modality Therapy; Cyclophosphamide; Cystitis; Cytarabine; Drug Therapy, Combination; Female; Germany, East; Humans; Leukemia; Male; Methotrexate; Mycoses; Stomatitis; Transplantation, Autologous; Transplantation, Homologous; Vincristine; Whole-Body Irradiation | 1984 |
Design of controlled clinical trials: use of historical controls.
Topics: Acute Disease; Adolescent; Adult; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Glioma; Humans; Leukemia; Male; Plicamycin; Random Allocation; Uracil; Vincristine | 1982 |
High-dose cytosine arabinoside therapy for refractory leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Bone Marrow Diseases; Cerebellar Ataxia; Cognition Disorders; Conjunctivitis; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Eruptions; Hemorrhage; Humans; Leukemia; Middle Aged | 1983 |
[Lung survival or healing? Description of a case of acute non-lymphoblastic leukosis].
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Follow-Up Studies; Humans; Leukemia; Male; Methotrexate; Thioguanine | 1984 |
High-dose cytosine arabinoside and m-AMSA is effective therapy in relapsed acute nonlymphocytic leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Aminoacridines; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Drug Eruptions; Hemorrhage; Humans; Leukemia; Middle Aged; Nausea; Recurrence; Vomiting | 1984 |
Prognostic factors in adult patients with acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Chromosome Aberrations; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Prednisolone; Prognosis; Vincristine; Zinostatin | 1983 |
Visceral herpesvirus infections in leukemic patients receiving cytarabine.
Topics: Adult; Cytarabine; Female; Herpesviridae Infections; Humans; Immunosuppression Therapy; Leukemia; Male; Risk; Skin Ulcer; Stomach Ulcer; Ulcer | 1980 |
Effects of tetrahydrouridine on the uptake and metabolism of 1-beta-D-arabinofuranosylcytosine in human normal and leukemic cells.
Topics: Bone Marrow; Cells, Cultured; Cytarabine; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Phosphotransferases; Tetrahydrouridine; Uridine | 1980 |
Human serum megakaryocyte colony-stimulating activity increases in response to intensive cytotoxic chemotherapy.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cells, Cultured; Colony-Stimulating Factors; Cytarabine; Daunorubicin; Humans; Leukemia; Megakaryocytes; Platelet Count; Thioguanine | 1984 |
Bone marrow ablation followed by allogeneic marrow grafting during first complete remission of acute nonlymphocytic leukemia.
Topics: Bone Marrow; Bone Marrow Transplantation; Cyclophosphamide; Cytarabine; Daunorubicin; Humans; Leukemia; Patient Isolation; Whole-Body Irradiation | 1983 |
A comparison of bone marrow transplantation with maintenance chemotherapy for patients with acute nonlymphoblastic leukemia in first complete remission.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transplantation; Cytarabine; Female; Graft vs Host Disease; Hematologic Diseases; Humans; Leukemia; Male; Recurrence; Thioguanine | 1984 |
Enhancement by methylxanthines of sister-chromatid exchange frequency induced by cytostatics in normal and leukemic human lymphocytes.
Topics: Caffeine; Cells, Cultured; Crossing Over, Genetic; Cytarabine; Drug Synergism; Humans; Leukemia; Lymphocytes; Mitomycin; Mitomycins; Mutagenicity Tests; Mutagens; Sister Chromatid Exchange; Xanthines | 1983 |
[Pharmacokinetics of intrathecal chemotherapy and clinical problems].
Topics: Acute Disease; Blood-Brain Barrier; Cytarabine; Humans; Infusions, Parenteral; Injections, Spinal; Kinetics; Leukemia; Meningeal Neoplasms; Methotrexate; Thiotepa | 1984 |
[ACNP therapy for DCMP-resistant acute leukemia (author's transl)].
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Agents; Cytarabine; Doxorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisolone; Zinostatin | 1981 |
[Characteristics of the electrophoretic mobility of blasts from acute non-lymphoid leukemias].
Topics: Acute Disease; Adult; Aged; Cytarabine; Electrophoresis; Female; Humans; Leukemia; Leukocytes; Male; Middle Aged | 1984 |
Prediction of response of acute nonlymphocytic leukaemia to therapy with 'high dose' cytosine arabinoside.
Topics: Age Factors; Aged; Bone Marrow; Cell Count; Cells, Cultured; Cytarabine; DNA; Humans; Leukemia; Middle Aged; Prognosis | 1984 |
The effect of low dose Ara-C in acute nonlymphoblastic leukaemias and atypical leukaemia.
Topics: Adult; Aged; Anemia, Aplastic; Cell Differentiation; Cells, Cultured; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged | 1984 |
High-dose cytosine arabinoside therapy for refractory leukemia.
Topics: Cytarabine; Graft vs Host Disease; Humans; Leukemia; Transfusion Reaction | 1984 |
Sequential combination of high dose ARA-C (HiDAC) and asparaginase (ASP) for the treatment of advanced acute leukemia and lymphoma.
Topics: Adolescent; Adult; Asparaginase; Cytarabine; Drug Therapy, Combination; Humans; Leukemia; Lymphoma | 1984 |
Probable cures of adult acute leukemia using short term intensive investigational chemotherapy.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Administration Schedule; Humans; Leukemia; Vincristine | 1984 |
Two-cycle timed-sequential chemotherapy for adult acute nonlymphocytic leukemia.
Topics: Acute Disease; Adult; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Humans; Leukemia; Recurrence | 1984 |
[High doses of cytosine arabinoside--a new use for an old drug].
Topics: Cytarabine; Humans; Leukemia | 1984 |
High-dose cytosine arabinoside. Active agent in treatment of non-Hodgkin's lymphoma.
Topics: Adult; Aged; Bone Marrow; Brain Neoplasms; Cytarabine; Female; Humans; Leukemia; Lymphoma; Male; Middle Aged; Spinal Cord Neoplasms | 1984 |
Quantitative analysis of chromosomal G-bands in human hematopoietic disorders by methotrexate synchronization technique.
Topics: Anemia; Bone Marrow; Cell Cycle; Chromosome Aberrations; Chromosome Banding; Chromosome Disorders; Cytarabine; Hematologic Diseases; Humans; Karyotyping; Kinetics; Leukemia; Metaphase; Methotrexate | 1984 |
Assessment of the drug sensitivity of acute nonlymphocytic leukaemia using the in vitro clonogenic assay.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cell Survival; Colony-Forming Units Assay; Cytarabine; Daunorubicin; Doxorubicin; Humans; Leukemia; Thioguanine; Tumor Stem Cell Assay | 1984 |
[Low-dose cytosine arabinoside (Ara-C) continuous infusion regimen for atypical nonlymphocytic leukemia--clinical study of the remission mechanism by serial chromosomal findings, colony formation and plasma Ara-C concentration].
Topics: Aged; Chromosome Aberrations; Cytarabine; Drug Administration Schedule; Female; Hematopoietic Stem Cells; Humans; Leukemia; Male; Middle Aged | 1984 |
[High-dose cytosine arabinoside therapy in refractory acute leukemia].
Topics: Acute Disease; Adult; Aged; Cytarabine; Drug Administration Schedule; Female; Humans; Leukemia; Male; Middle Aged | 1984 |
High-dose cytosine arabinoside therapy in acute non-lymphocytic leukemia.
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Humans; Leukemia; Middle Aged | 1984 |
[Biochemical criteria of the sensitivity of patients with leukosis to 6-mercaptopurine and cytosar].
Topics: Adult; Child, Preschool; Cytarabine; DNA, Neoplasm; Humans; Leukemia; Mercaptopurine; Middle Aged | 1984 |
The use of human cancer cell lines as a primary screening system for antineoplastic compounds.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line; Cell Survival; Colonic Neoplasms; Cytarabine; Drug Evaluation, Preclinical; Drug Resistance; Female; Fluorouracil; Humans; Leukemia; Methotrexate; Neoplasms | 1984 |
Inhibition of DNA synthesis by cytosine arabinoside: relation to response of acute non-lymphocytic leukemia to remission induction therapy and to stage of the disease.
Topics: Acute Disease; Aged; Cytarabine; DNA, Neoplasm; Humans; In Vitro Techniques; Interphase; Leukemia; Neoplasm Staging | 1984 |
[Treatment of acute leukemia].
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Deoxycytidine Monophosphate; Humans; Leukemia; Mercaptopurine; Prednisolone | 1984 |
Proliferation kinetics and prediction of chemotherapeutic effect in adult acute leukemia according to the FAB classification.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cell Division; Cytarabine; Daunorubicin; Female; Humans; Kinetics; Leukemia; Male; Mercaptopurine; Middle Aged; Neoplastic Stem Cells; Prednisolone; Prognosis | 1984 |
[Acute pancreatitis during the treatment of BH-AC AMP regimen for acute non-lymphocytic leukemia].
Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia; Male; Mercaptopurine; Middle Aged; Naphthacenes; Pancreatitis; Prednisolone | 1984 |
Acridinyl anisidide (m-AMSA) therapy in 11 patients with refractory acute leukemia.
Topics: Adolescent; Adult; Aminoacridines; Amsacrine; Bone Marrow; Cytarabine; Drug Evaluation; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Leukemia; Male; Pancytopenia; Thioguanine | 1984 |
History of intrathecal prophylaxis and therapy of meningeal leukemia.
Topics: Animals; Child; Cytarabine; Humans; Injections, Spinal; Kinetics; Leukemia; Meningeal Neoplasms; Methotrexate | 1983 |
Cytarabine (Ara-C): a drug profile.
Topics: Adult; Child; Cytarabine; Humans; Kinetics; Leukemia | 1984 |
Idiopathic refractory sideroachrestic anemia (IRSA) progressing to acute mixed lymphoblastic-myelomonoblastic leukemia. Case report and review of the literature.
Topics: Aged; Anemia, Sideroblastic; Bone Marrow Examination; Cerebrospinal Fluid; Cytarabine; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Pneumonia; Prednisone; Thioguanine; Tuberculosis, Miliary; Vincristine | 1983 |
Clinical correlations of leukemic clonogenic cell chemosensitivity assessed by in vitro continuous exposure to drugs.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Bone Marrow; Clone Cells; Cytarabine; Drug Administration Schedule; Drug Evaluation, Preclinical; Drug Therapy, Combination; Drug Tolerance; Female; Humans; Leukemia; Male; Methods; Middle Aged; Naphthacenes | 1983 |
Recognition of drug resistance during remission induction therapy for acute non-lymphocytic leukemia: utility of day 6 bone marrow biopsy.
Topics: Acute Disease; Aged; Antibiotics, Antineoplastic; Bone Marrow Examination; Cytarabine; Drug Resistance; Drug Therapy, Combination; Humans; Leukemia; Naphthacenes | 1983 |
Therapy of secondary acute nonlymphocytic leukemia.
Topics: Acute Disease; Antibiotics, Antineoplastic; Cytarabine; Drug Therapy, Combination; Humans; Leukemia; Naphthacenes | 1983 |
Pericarditis as presenting manifestation of acute nonlymphocytic leukemia in a young child.
Topics: Acute Disease; Child, Preschool; Cytarabine; Diagnosis, Differential; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Pericarditis; Thioguanine | 1983 |
[Changes of therapy results in acute leukemia under different treatment schedules with special reference to gnotobiotic measures].
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents; Asparaginase; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Patient Isolation; Prednisolone; Thioguanine; Vincristine | 1983 |
[VP 16-213 in the treatment of acute leukemia in childhood].
Topics: Acute Disease; Adolescent; Antineoplastic Agents; Child; Child, Preschool; Cytarabine; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Humans; Leukemia; Leukemia, Lymphoid; Male; Podophyllotoxin | 1983 |
[Aclacinomycin A and behenoyl ara-C combination chemotherapy for untreated acute non-lymphocytic leukemia].
Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged; Naphthacenes | 1983 |
Long term follow-up of remission patients in adult acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Female; Follow-Up Studies; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Prognosis; Time Factors; Vincristine | 1983 |
Therapeutic activity of 4-demethoxydauno-rubicin (idarubicin) in adult acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Daunorubicin; Drug Evaluation; Female; Humans; Idarubicin; Leukemia; Male; Middle Aged; Time Factors | 1983 |
Relationship between the per cent of marrow cells in S phase and the outcome of remission-induction therapy for acute nonlymphocytic leukaemia.
Topics: Acute Disease; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Female; Humans; Interphase; Leukemia; Male; Middle Aged; Naphthacenes; Thioguanine | 1984 |
Effect of dose and schedule on pharmacokinetics of high-dose cytosine arabinoside in plasma and cerebrospinal fluid.
Topics: Cytarabine; Drug Administration Schedule; Humans; Kinetics; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma | 1983 |
[Central nervous system involvement in adult acute leukemia].
Topics: Acute Disease; Adult; Aged; Brain Neoplasms; Combined Modality Therapy; Cytarabine; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged | 1984 |
The relationship between growth in agar, karyotype and prognosis in acute leukaemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells; Cells, Cultured; Chromosome Aberrations; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Karyotyping; Leukemia; Leukemia, Lymphoid; Male; Middle Aged; Neoplastic Stem Cells; Prednisolone; Prednisone; Prognosis; Thioguanine; Vincristine | 1984 |
High dose araC in acute nonlymphocytic leukemia complicating Hodgkin's disease.
Topics: Acute Disease; Cytarabine; Dose-Response Relationship, Drug; Hodgkin Disease; Humans; Leukemia; Male; Middle Aged | 1983 |
Continuous infusion high-dose cytosine arabinoside in refractory childhood leukemia.
Topics: Acute Disease; Adolescent; Arabinofuranosylcytosine Triphosphate; Bone Marrow; Child; Child, Preschool; Cytarabine; Deoxycytosine Nucleotides; Drug Administration Schedule; Humans; Infusions, Parenteral; Kinetics; Leukemia; Leukemia, Lymphoid | 1984 |
In vitro assessment of drug sensitivity in acute nonlymphocytic leukemia.
Topics: Acute Disease; Antibiotics, Antineoplastic; Antineoplastic Agents; Biological Transport; Colony-Forming Units Assay; Cytarabine; Drug Evaluation, Preclinical; Humans; Leukemia; Naphthacenes; Prognosis; Tumor Stem Cell Assay | 1984 |
Aclarubicin in the treatment of acute nonlymphocytic leukemia refractory to treatment with daunorubicin and cytarabine: a phase II trial.
Topics: Aclarubicin; Acute Disease; Adult; Aged; Antibiotics, Antineoplastic; Cytarabine; Daunorubicin; Drug Evaluation; Heart; Humans; Leukemia; Leukopenia; Middle Aged; Naphthacenes; Prospective Studies; Thrombocytopenia | 1984 |
Phase I and early phase II study of PL-AC [N4-palmitoyl-(1-beta-D-arabinofuranosyl) cytosine] on hematopoietic malignancies.
Topics: Adolescent; Adult; Child; Cytarabine; Drug Administration Schedule; Drug Evaluation; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma; Male; Middle Aged | 1984 |
[Sunrabin for injection].
Topics: Acute Disease; Adult; Animals; Antineoplastic Agents; Cytarabine; Humans; Injections; Lethal Dose 50; Leukemia; Mice; Rats | 1983 |
The clonogenic assay as a reproducible in vitro system to study predictive parameters of treatment outcome in acute nonlymphoblastic leukemia.
Topics: Acute Disease; Bone Marrow Cells; Clone Cells; Colony-Forming Units Assay; Cytarabine; Doxorubicin; Drug Evaluation, Preclinical; Drug Resistance; Humans; Leukemia; Prognosis; Recurrence | 1983 |
A rapid in vitro drug-sensitivity assay in acute nonlymphocytic leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Cells, Cultured; Cytarabine; Daunorubicin; Drug Evaluation, Preclinical; Female; Hematopoietic Stem Cells; Humans; Leukemia; Male; Middle Aged; Sulfates; Sulfur Radioisotopes | 1983 |
[Prediction of the response of patients with acute leukemia to chemotherapeutic agents by tritiated thymidine uptake by leukocytes].
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia; Leukocytes; Male; Middle Aged; Thymidine; Tritium | 1983 |
Cytarabine: low-dose, high-dose, no dose?
Topics: Cytarabine; Drug Administration Schedule; Humans; Leukemia | 1983 |
Cerebellar degeneration caused by high-dose cytosine arabinoside: a clinicopathological study.
Topics: Acute Disease; Adolescent; Adult; Aged; Cerebellar Ataxia; Cerebellar Cortex; Cerebellar Nuclei; Cerebellum; Cytarabine; Dose-Response Relationship, Drug; Eye Movements; Female; Humans; Leukemia; Male; Middle Aged; Nerve Degeneration; Nystagmus, Pathologic; Purkinje Cells | 1983 |
Phase I trial of cytarabine and hydroxyurea.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Child; Cytarabine; Drug Evaluation; Drug Resistance; Female; Gastrointestinal Diseases; Humans; Hydroxyurea; Leukemia; Lymphoma; Male; Middle Aged; Skin Diseases | 1983 |
Gastrointestinal necrosis in acute leukemia: a complication of induction therapy.
Topics: Cytarabine; Gastrointestinal Diseases; Humans; Leukemia; Necrosis | 1983 |
Alteration of the pharmacokinetics of high-dose ara-C by its metabolite, high ara-U in patients with acute leukemia.
Topics: Acute Disease; Arabinofuranosyluracil; Chromatography, High Pressure Liquid; Cytarabine; Cytidine Deaminase; Dose-Response Relationship, Drug; Humans; Infusions, Parenteral; Kinetics; Leukemia; Models, Biological; Nucleoside Deaminases; Radioimmunoassay; Time Factors; Uridine | 1983 |
[Leukemic colony (L-CFU) formation in vitro: clinical correlations of the in vitro growth pattern of L-CFU and drug sensitivity in acute leukemia].
Topics: Acute Disease; Cell Division; Colony-Forming Units Assay; Cytarabine; Daunorubicin; Deoxycytidine Monophosphate; Humans; Leukemia; Tumor Stem Cell Assay | 1983 |
Colony forming ability of bone marrow cells from patients with acute leukemia.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Colony-Forming Units Assay; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Mercaptopurine; Middle Aged; Prednisolone; Prognosis | 1983 |
Cytosine arabinoside transport by human leukaemic cells.
Topics: Acute Disease; Adolescent; Adult; Aged; Biological Transport; Cell Membrane; Child; Child, Preschool; Cytarabine; Deoxycytidine; Humans; Infant; Kinetics; Leukemia; Leukocytes; Middle Aged; Phloretin; Thioinosine | 1983 |
Leukemic cell differentiation in vivo and in vitro: arrest of proliferation parallels the differentiation induced by the antileukemic drug Harringtonine.
Topics: Acute Disease; Adult; Alkaloids; Cell Differentiation; Cell Division; Cell Line; Clone Cells; Cytarabine; Female; Harringtonines; Humans; Leukemia; Male; Middle Aged; Monocytes; Thioguanine | 1984 |
Acute doxorubicin toxicity. Relationship to pretreatment liver function, response, and pharmacokinetics in patients with acute nonlymphocytic leukemia.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Doxorubicin; Drug Administration Schedule; Drug Evaluation; Female; Humans; Kinetics; Leukemia; Liver; Liver Function Tests; Male; Middle Aged; Prognosis | 1984 |
Thymidine as a kinetic and biochemical modulator of 1-beta-D-arabinofuranosylcytosine in human acute nonlymphocytic leukemia.
Topics: Acute Disease; Adult; Cytarabine; Deoxycytidine; Female; Humans; Interphase; Kinetics; Leukemia; Male; Middle Aged; Phosphorylation; Thymidine | 1984 |
High-dose cytosine arabinoside for acute nonlymphocytic leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia; Liver; Male | 1984 |
Treatment of poor risk acute leukemia with sequential high-dose ARA-C and asparaginase.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cell Transformation, Neoplastic; Child; Cytarabine; Drug Resistance; Female; Humans; Leukemia; Male; Middle Aged | 1984 |
Differentiation versus cytoreduction during remission induction in acute nonlymphoblastic leukemia treated with sequential high-dose ara-C and asparaginase.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow; Cell Differentiation; Cytarabine; Hematopoietic Stem Cells; Humans; Leukemia; Leukocyte Count; Male; Middle Aged | 1984 |
High-dose cytosine arabinoside: response to therapy in acute leukaemia and non-Hodgkin's lymphoma.
Topics: Adolescent; Adult; Aged; Alopecia; Child; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia; Middle Aged; Nausea; Neutropenia | 1984 |
Synergistic inhibition of human leukemia cell growth by deoxyguanosine and 1-beta-D-arabinofuranosylcytosine.
Topics: Cell Line; Cytarabine; Deoxyguanosine; Drug Synergism; Guanosine Triphosphate; Humans; Leukemia; Phosphorylation | 1984 |
Acute cerebellar dysfunction with high-dose Ara-C therapy.
Topics: Acute Disease; Adult; Cerebellar Diseases; Cytarabine; Humans; Leukemia | 1984 |
Successful treatment of meningeal leukemia using systemic high-dose cytosine arabinoside.
Topics: Acute Disease; Adult; Aged; Cytarabine; Drug Evaluation; Female; Humans; Injections, Intravenous; Leukemia; Male; Meningeal Neoplasms; Middle Aged; Recurrence | 1984 |
The use of intermediate dose cytosine arabinoside (ID Ara-C) in the treatment of acute non-lymphocytic leukaemia in relapse.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Doxorubicin; Half-Life; Humans; Leukemia; Middle Aged; Vincristine | 1984 |
TdT-positive acute leukemia with monocytoid characteristics: clinical, cytochemical, cytogenetic, and immunologic findings.
Topics: Acute Disease; Adult; Aged; Antibodies, Monoclonal; Cell Membrane; Chromosome Aberrations; Cytarabine; Daunorubicin; DNA Nucleotidylexotransferase; DNA Nucleotidyltransferases; Female; Histocytochemistry; Humans; Leukemia; Male; Middle Aged; Monocytes; Neoplastic Stem Cells; Phenotype; Prednisone; Vincristine | 1984 |
Thyroid dysfunction among long-term survivors of bone marrow transplantation.
Topics: Adolescent; Adult; Anemia, Aplastic; Bone Marrow Transplantation; Carmustine; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Female; Humans; Immunologic Deficiency Syndromes; Infant; Leukemia; Lymphoma; Male; Radiation Injuries; Thyroid Diseases; Thyroid Function Tests; Time Factors; Whole-Body Irradiation | 1982 |
Bone marrow transplantation with high-dose cytosine arabinoside.
Topics: Bone Marrow Transplantation; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia | 1982 |
Modulation of the cellular pharmacology and clinical toxicity of 1-beta-D-arabinofuranosylcytosine.
Topics: Arabinofuranosylcytosine Triphosphate; Cell Line; Cytarabine; Deoxyribonucleotides; DNA; Drug Therapy, Combination; Humans; Hydroxyurea; Leukemia; Ribonucleotide Reductases; Ribonucleotides; Thymidine | 1982 |
Pharmacologic and clinical studies of N4-behenoyl-1-beta-D-arabinofuranosylcytosine.
Topics: Animals; Bone Marrow; Cytarabine; Drug Evaluation; Female; Haplorhini; Humans; Leukemia; Macaca; Male; Middle Aged; Neoplasms; Remission, Spontaneous | 1980 |
[Acute adult leukemia. Therapeutic options including supportive measures].
Topics: Acute Disease; Adrenal Cortex Hormones; Adult; Asparaginase; Cytarabine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Humans; Leukemia; Methotrexate; Remission, Spontaneous; Vincristine | 1980 |
High remission induction (traditional sino-western HOAP) regimen for acute nonlymphocytic leukemia.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Agents; Child; Cytarabine; Drug Therapy, Combination; Female; Harringtonines; Homoharringtonine; Humans; Leukemia; Male; Medicine, Chinese Traditional; Middle Aged; Prednisone; Vincristine | 1980 |
Long-term disease-free survival in acute nonlymphocytic leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Cytarabine; Daunorubicin; Female; Humans; Leukemia; Long-Term Care; Male; Middle Aged; Prednisone; Recurrence; Thioguanine | 1981 |
Diamine oxidase as a plasma marker of rat intestinal mucosal injury and regeneration after administration of 1-beta-D-arabinofuranosylcytosine.
Topics: Alkaline Phosphatase; alpha-Glucosidases; Amine Oxidase (Copper-Containing); Animals; Cytarabine; Disaccharidases; Female; Humans; Injections, Subcutaneous; Intestinal Diseases; Intestinal Mucosa; Leukemia; Rats; Regeneration; Time Factors | 1981 |
Central and peripheral myelinopathy associated with systemic neoplasia and chemotherapy.
Topics: Adult; Aged; Axons; Brain; Cytarabine; Cytoskeleton; Female; Humans; Injections, Spinal; Leukemia; Male; Melanoma; Middle Aged; Myelin Sheath; Skin Neoplasms; Spinal Cord; Thiotepa | 1981 |
Hypoparathyroidism and hypocalcaemia during treatment for acute leukaemia.
Topics: Adolescent; Adult; Aged; Child; Cytarabine; Doxorubicin; Female; Humans; Hypocalcemia; Hypoparathyroidism; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Magnesium; Male; Middle Aged; Parathyroid Hormone | 1982 |
Remission-induction, consolidation and maintenance therapy by AVA protocol in acute nonlymphoblastic leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Child; Child, Preschool; Cytarabine; Doxorubicin; Female; Humans; Leukemia; Male; Middle Aged; Vincristine | 1982 |
Adverse effects of aneuploidy on the outcome of remission induction therapy for acute nonlymphocytic leukaemia: analysis of types of treatment failure.
Topics: Acute Disease; Aneuploidy; Bone Marrow; Cytarabine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Female; Humans; Karyotyping; Leukemia; Male; Metaphase; Middle Aged; Prognosis | 1983 |
Effects of 12-O-tetradecanoylphorbol-13-acetate on the proliferation and differentiation of normal and leukemic myeloid progenitor cells.
Topics: Bone Marrow; Cell Differentiation; Cell Division; Cells, Cultured; Culture Media; Cytarabine; Humans; Leukemia; Macrophages; Neutrophils; Phorbols; Tetradecanoylphorbol Acetate | 1983 |
Posttransfusion hepatitis in acute nonlymphocytic leukemia: lack of a beneficial influence.
Topics: Acute Disease; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Hepatitis; Humans; Leukemia; Male; Prognosis; Transfusion Reaction | 1983 |
Therapy of secondary acute nonlymphocytic leukemia with cytarabine.
Topics: Acute Disease; Adult; Aged; Chromosome Aberrations; Cytarabine; Humans; Leukemia; Middle Aged | 1983 |
Cell kinetic responses in childhood acute nonlymphocytic leukemia during high-dose therapy with cytosine arabinoside.
Topics: Acute Disease; Adolescent; Bone Marrow; Bone Marrow Cells; Cell Division; Child; Child, Preschool; Cytarabine; DNA; Dose-Response Relationship, Drug; Female; Humans; Kinetics; Leukemia; Male | 1983 |
Pharmacokinetics of N4-behenoyl-1-beta-D-arabinofuranosylcytosine in patients with acute leukemia.
Topics: Acute Disease; Adult; Antineoplastic Agents; Arabinofuranosyluracil; Bone Marrow; Child; Child, Preschool; Chromatography, High Pressure Liquid; Cytarabine; Erythrocytes; Gas Chromatography-Mass Spectrometry; Humans; Infant; Infusions, Parenteral; Kinetics; Leukemia; Middle Aged; Time Factors | 1983 |
High-dose cytarabine in acute leukemia: toxicity and pharmacokinetics.
Topics: Acute Disease; Adolescent; Adult; Cytarabine; Cytidine Deaminase; Female; Half-Life; Humans; Kinetics; Leukemia; Leukocyte Count; Male; Middle Aged; Nausea; Nucleoside Deaminases; Vomiting | 1983 |
Does treatment with ARA-C in low dosage cause differentiation of leukemic cells?
Topics: Acute Disease; Aged; Cell Differentiation; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia | 1983 |
The clinical pharmacology of cytosine arabinoside.
Topics: Cytarabine; Humans; Infusions, Parenteral; Injections, Intravenous; Injections, Subcutaneous; Kinetics; Leukemia; Lymphoma | 1983 |
A phase I-II study of combination therapy with thymidine and cytosine arabinoside.
Topics: Adolescent; Adult; Child; Child, Preschool; Cytarabine; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Infant; Leukemia; Lymphoma; Male; Middle Aged; Thymidine | 1983 |
Central nervous system toxicity of high-dose cytosine arabinoside.
Topics: Acute Disease; Adult; Aged; Central Nervous System; Cerebellum; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged | 1983 |
[Therapeutic results of DCMP therapy (2M-80) in acute non-lymphocytic leukemia--the relationship between the residual leukemic cells and duration of remission].
Topics: Acute Disease; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Humans; Leukemia; Mercaptopurine; Middle Aged; Prednisolone | 1982 |
Treatment of acute leukemia in relapse with 4'(9-acridinylamino) methanesulfon-m-anisidide (AMSA) in combination with cytosine arabinoside and thioguanine.
Topics: Acute Disease; Adolescent; Adult; Aged; Aminoacridines; Amsacrine; Antineoplastic Agents; Chemical and Drug Induced Liver Injury; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Middle Aged; Neoplasm Recurrence, Local; Thioguanine | 1981 |
Cytokinetically based induction chemotherapy and splenectomy for childhood acute nonlymphocytic leukemia.
Topics: Acute Disease; Adolescent; Asparaginase; Brain Neoplasms; Child; Cyclophosphamide; Cytarabine; Doxorubicin; Humans; Injections, Spinal; Leukemia; Mercaptopurine; Methotrexate; Prednisone; Splenectomy; Vincristine | 1982 |
Cytostatic drugs are without significant effect on digitoxin plasma level and renal excretion.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Digitoxin; Female; Heart Failure; Humans; Leukemia; Lymphoma; Male; Middle Aged; Prednisone; Procarbazine; Vincristine | 1982 |
The efficiency of strict reverse isolation and antimicrobial decontamination in remission induction therapy of acute leukemia.
Topics: Acute Disease; Adult; Cytarabine; Daunorubicin; Decontamination; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Patient Isolation; Retrospective Studies | 1980 |
Myeloblastic leukemia and leukemic meningitis in a dog.
Topics: Animals; Cytarabine; Dog Diseases; Dogs; Female; Leukemia; Leukemia, Myeloid, Acute; Meningitis; Thioguanine | 1980 |
Cytokinetic changes in the peripheral blood of leukemic patients during cytostatic therapy. VI. Effect of arabinosylcytosine.
Topics: Adult; Aged; Blood Cells; Cytarabine; DNA; Female; Humans; Interphase; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Primary Myelofibrosis | 1980 |
Simultaneous determination of 1-beta-D-arabinofuranosylcytosine 5'-triphosphate and 3-deazauridine 5'-triphosphate in human leukemia cells by high-performance liquid chromatography.
Topics: 3-Deazauridine; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cells, Cultured; Chromatography, High Pressure Liquid; Cytarabine; Cytidine Triphosphate; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Uracil Nucleotides; Uridine; Uridine Triphosphate | 1980 |
Re-induction of complete remissions in adults with acute non-lymphocytic leukemia.
Topics: Cytarabine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Thioguanine | 1981 |
A four-year experience with anthracycline, cytosine arabinoside, vincristine and prednisone combination chemotherapy in 325 adults with acute leukemia.
Topics: Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Cytarabine; Drug Administration Schedule; Drug Therapy, Combination; Female; Glycosides; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Naphthacenes; Prednisone; Vincristine | 1981 |
[Treatment of acute non-lymphocytic leukemia with concurrent administration of N4-behenoyl-beta-D-arabinofuranosylcytosine, aclacinomycin A, 6-mercaptopurine and prednisolone; a pilot study (author's transl)].
Topics: Aclarubicin; Adult; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Naphthacenes; Prednisolone | 1981 |
Chemotherapy of leukemia in mice, rats, and humans relating time of humoral stimulation, tumor growth, and clinical response.
Topics: Animals; Cell Division; Cytarabine; Daunorubicin; DNA, Neoplasm; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia L1210; Leukemia, Experimental; Leukemia, Myeloid, Acute; Mice; Rats | 1981 |
Cytosine arabinoside influx and nucleoside transport sites in acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Binding Sites; Bone Marrow Cells; Carrier Proteins; Cell Transformation, Neoplastic; Child; Child, Preschool; Cytarabine; Humans; Infant; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Middle Aged; Nucleosides; Thioinosine; Time Factors | 1982 |
A pilot study of high-dose 1-beta-D-arabinofuranosylcytosine for acute leukemia and refractory lymphoma: clinical response and pharmacology.
Topics: Adolescent; Adult; Aged; Blood; Bone Marrow; Brain; Brain Neoplasms; Child; Cytarabine; Drug Evaluation; Eye; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma; Male; Middle Aged; Pilot Projects | 1982 |
Anthracyclines in the treatment of acute nonlymphocytic leukemias.
Topics: Acute Disease; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Bone Marrow; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Heart Diseases; Humans; Leukemia; Middle Aged; Naphthacenes | 1981 |
Vincristine and prednisolone therapy in blast crisis of chronic myelogenous leukaemia in childhood.
Topics: Adolescent; Child; Cyclophosphamide; Cytarabine; DNA Nucleotidylexotransferase; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Meningeal Neoplasms; Prednisolone; Prognosis; Vincristine | 1981 |
Retrospective analysis of 158 cases of adult acute leukaemia: factors influencing prognosis and treatment response.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Karyotyping; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Middle Aged; Prednisolone; Prognosis; Regression Analysis; Retrospective Studies; Thioguanine; Vincristine | 1982 |
[Adriamycin and Ara-C infusions in the treatment of refractory leukemia].
Topics: Acute Disease; Adolescent; Child; Child, Preschool; Cytarabine; Doxorubicin; Drug Administration Schedule; Female; Humans; Infusions, Intra-Arterial; Leukemia; Leukemia, Lymphoid; Male | 1982 |
[Comparative evaluation of a combination of daunorubicin and cytosine arabinoside and that of aclarubicin and cytosine arabinoside in remission induction in acute non-lymphocytic leukemia].
Topics: Aclarubicin; Adult; Aged; Antibiotics, Antineoplastic; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Naphthacenes; Random Allocation | 1982 |
The University of Cape Town leukaemia centre: the first 5 years.
Topics: Academic Medical Centers; Acute Disease; Bone Marrow Transplantation; Cytarabine; Doxorubicin; Drug Therapy, Combination; Humans; Leukapheresis; Leukemia; Podophyllotoxin; South Africa; Transplantation, Homologous | 1980 |
High dose chemotherapy and autologous bone marrow transplantation in acute leukemias, malignant lymphomas and solid tumors. A study of 23 patients.
Topics: Adolescent; Adult; Bone Marrow Transplantation; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Female; Freezing; Hematopoiesis; Humans; Leukemia; Leukocyte Count; Lomustine; Lymphoma; Male; Middle Aged; Neoplasms; Platelet Count; Thioguanine; Transplantation, Autologous | 1981 |
Treatment of early acute nonlymphatic leukemia with low dose cytosine arabinoside.
Topics: Adult; Aged; Animals; Bone Marrow; Bone Marrow Transplantation; Cell Division; Cytarabine; Drug Administration Schedule; Female; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Rats | 1981 |
Predictive value of the CFU-C assay in acute nonlymphocytic leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Bone Marrow Transplantation; Child; Child, Preschool; Colony-Forming Units Assay; Cytarabine; Doxorubicin; Drug Therapy, Combination; Humans; Leukemia; Middle Aged; Naphthacenes; Prognosis | 1982 |
Bone marrow cell count per cubic millimeter bone marrow: a new parameter for quantitating therapy-induced cytoreduction in acute leukemia.
Topics: Acute Disease; Bone Marrow; Cell Count; Cytarabine; Daunorubicin; Humans; Leukemia; Thioguanine; Thymidine | 1982 |
Acute leukemia in idiopathic sideroblastic anemia: response to combination chemotherapy.
Topics: Acute Disease; Aged; Anemia, Sideroblastic; Blood Transfusion; Cytarabine; Drug Therapy, Combination; Humans; Leukemia; Male; Middle Aged; Prednisone; Time Factors; Vincristine | 1982 |
Cell kinetics in acute leukemia: a critical reevaluation based on new data.
Topics: Biopsy; Bone Marrow; Cytarabine; DNA; Drug Therapy, Combination; Flow Cytometry; Humans; Interphase; Kinetics; Leukemia; Mitotic Index | 1982 |
Role of dephosphorylation in accumulation of 1-beta-D-arabinofuranosylcytosine 5'-triphosphate in human lymphoblastic cell lines with reference to their drug sensitivity.
Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cell Division; Cell Line; Cells, Cultured; Cytarabine; DNA, Neoplasm; Humans; Hydroxyurea; Leukemia; Lymphoma; Phosphorylation; Thymidine | 1982 |
Chemotherapy sensitivity assessment of leukemic colony-forming cells with in vitro simultaneous exposure to multiple drugs: clinical correlations in acute nonlymphocytic leukemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clone Cells; Cytarabine; Daunorubicin; Doxorubicin; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Middle Aged; Prednisone; Vincristine | 1982 |
Treatment of refractory acute nonlymphocytic leukemia with a combination of pyrazofurin and cytarabine.
Topics: Acute Disease; Amides; Antibiotics, Antineoplastic; Cytarabine; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Humans; Leukemia; Pyrazoles; Ribonucleosides; Ribose | 1982 |
A prognostic factor analysis for use in development of predictive models for response in adult acute leukemia.
Topics: Acute Disease; Adult; Aged; Antibiotics, Antineoplastic; Bone Marrow; Cytarabine; Daunorubicin; Doxorubicin; Female; Humans; Leukemia; Male; Middle Aged; Prednisone; Prognosis; Vincristine | 1982 |
Prediction of remission in adult acute leukemia: development and testing of predictive models.
Topics: Acute Disease; Adult; Aged; Antibiotics, Antineoplastic; Cytarabine; Daunorubicin; Doxorubicin; Humans; Leukemia; Middle Aged; Models, Biological; Prednisone; Prognosis; Regression Analysis; Vincristine | 1982 |
Radioimmunoassay of 1-beta-D-arabinofuranosylcytosine.
Topics: Animals; Cytarabine; Humans; Hydrogen-Ion Concentration; Leukemia; Mice; Rabbits; Radioimmunoassay; Structure-Activity Relationship | 1982 |
Efficacy of granulocyte transfusions collected from nonstimulated donors.
Topics: Acute Disease; Aged; Agranulocytosis; Blood Donors; Blood Transfusion; Centrifugation; Cytarabine; Doxorubicin; Fever; Humans; Leukapheresis; Leukemia; Leukocyte Transfusion; Middle Aged; Premedication | 1982 |
Clinical results and pharmacokinetics of high-dose cytosine arabinoside (HD ARA-C).
Topics: Adult; Arabinofuranosyluracil; Cytarabine; Drug Administration Schedule; Female; Gastrointestinal Diseases; Half-Life; Humans; Kinetics; Leukemia; Male; Metabolic Clearance Rate; Middle Aged; Teratoma; Time Factors | 1982 |
Absence of predictive parameters for CNS involvement in adult non-lymphocytic leukaemia at time of diagnosis.
Topics: Adult; Central Nervous System Diseases; Cytarabine; Female; Fever; Hepatomegaly; Humans; Leukemia; Lymph Nodes; Male; Methotrexate; Middle Aged; Splenomegaly | 1982 |
Acute nonlymphoblastic leukemia: prognostic factors in adults with long-term follow-up.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bacterial Vaccines; Carmustine; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydroxyurea; Leukemia; Male; Methotrexate; Middle Aged; Platelet Count; Prognosis; Pseudomonas; Statistics as Topic; Thioguanine; Vincristine | 1982 |
Results of aggressive chemotherapy for acute nonlymphoblastic leukemia in adults.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents; Cytarabine; Daunorubicin; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Humans; Leukemia; Male; Middle Aged; Prednisone; Thioguanine; Time Factors; Vincristine | 1982 |
Sequential vincristine, arabinosylcytosine and adriamycin in acute leukemia: cytologic and cytokinetic studies.
Topics: Acute Disease; Cytarabine; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Humans; Interphase; Leukemia; Vincristine | 1982 |
The kinetics of leukemic blast cells in man and the cytokinetic effect of cytostatic agents in vivo.
Topics: Blood Cells; Cell Cycle; Cytarabine; Daunorubicin; Humans; Kinetics; Leukemia; Methotrexate; Mitotic Index; Neoplastic Cells, Circulating; Prednisone; Vincristine | 1982 |
Recruitment of quiescent tumor by humoral stimulatory activity: requirements for successful chemotherapy.
Topics: Acute Disease; Animals; Cell Division; Cell Survival; Cells, Cultured; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Leukemia; Leukemia, Experimental; Rats | 1982 |
Two simple high-performance liquid chromatographic methods for simultaneous determination of 2'-deoxycytidine 5'-triphosphate and cytosine arabinoside 5'-triphosphate concentrations in biological samples.
Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Bone Marrow; Child; Chromatography, High Pressure Liquid; Cytarabine; Deoxycytosine Nucleotides; Humans; Leukemia; Spectrophotometry, Ultraviolet | 1982 |
Brook Lodge Symposium on "The pharmacology of Cytosar-U as it relates to its therapeutic usage". Kalamazoo, Michigan, December 13-15, 1981.
Topics: Cytarabine; Humans; Leukemia | 1982 |
Effect of schedule and combinations on clinical effectiveness of Ara-C in adult acute leukemia.
Topics: Adult; Cytarabine; Drug Administration Schedule; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Humans; Leukemia | 1982 |
Relationship between plasma Ara-C and intracellular Ara-CTP pools under conditions of continuous infusion and high-dose Ara-C treatment.
Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cytarabine; Dose-Response Relationship, Drug; Humans; Kinetics; Leukemia | 1982 |
Adriamycin combined with 10-day Ara-C, vincristine, and prednisone (10-day ADOAP) in the treatment of adult acute leukemia patients under fifty years of age. A Southwest Oncology Group Study.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Agents; Bone Marrow; Cytarabine; Doxorubicin; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Middle Aged; Prednisone; United States; Vincristine | 1982 |
Rubidazone in combination with Ara-C, vincristine and prednisone (ROAP) in the treatment of adult acute leukemia. A Southwest Oncology Group Study.
Topics: Acute Disease; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Bone Marrow; Cytarabine; Daunorubicin; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Middle Aged; Prednisone; United States; Vincristine | 1982 |
[DCTP (I) combination chemotherapy of adult acute non-lymphocytic leukemia].
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Middle Aged; Prednisolone; Thioguanine | 1982 |
The management of acute non-lymphocytic leukaemia in adults. Evaluation of the results in a non-selected group of 114 patients.
Topics: Acute Disease; Aged; Cytarabine; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Middle Aged; Retrospective Studies; Vincristine | 1982 |
[An in vitro chemotherapy sensitivity test on leukemic colony-forming cells (L-CFU) and its clinical evaluation].
Topics: Acute Disease; Antineoplastic Agents; Colony-Forming Units Assay; Cytarabine; Daunorubicin; Drug Evaluation, Preclinical; Drug Resistance; Hematopoietic Stem Cells; Humans; In Vitro Techniques; Leukemia | 1982 |
Teratogenic effects of antileukemic chemotherapy.
Topics: Abnormalities, Drug-Induced; Adult; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Infant, Newborn; Leukemia; Male; Pregnancy; Pregnancy Complications; Thioguanine; Thumb; Toes | 1981 |
Cytokinetic changes after cytosine arabinoside in acute non-lymphocyte leukemia.
Topics: Adult; Cell Cycle; Cytarabine; DNA; Dose-Response Relationship, Drug; Female; Humans; Leukemia; Male; Middle Aged; Time Factors | 1981 |
Phase I--II study of N4-behenoyl-1-beta-D-arabinofuranosylcytosine.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Child; Cytarabine; Drug Evaluation; Female; Humans; Leukemia; Male; Middle Aged; Neoplasms | 1981 |
Maintenance management of acute nonlymphocytic leukemia.
Topics: Acute Disease; Adult; Aged; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Middle Aged; Statistics as Topic; Thioguanine; Time Factors | 1981 |
Induction therapy and intensive consolidation with daunorubicin, cytosine arabinoside, and 6-thioguanine in adult acute nonlymphoblastic leukemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Agents; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Middle Aged; Thioguanine | 1981 |
Determination of 1-beta-D-arabinofuranosylcytosine and 1-beta-D-arabinofuranosyluracil in human plasma by high-performance liquid chromatography.
Topics: Arabinofuranosyluracil; Chromatography, High Pressure Liquid; Cytarabine; Humans; Leukemia; Uridine | 1981 |
Treatment of refractory adult acute lymphocytic leukaemia and acute undifferentiated leukaemia with an anthracycline antibiotic and cytosine arabinoside.
Topics: Adolescent; Adult; Aged; Cytarabine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Lymphoid; Male; Middle Aged; Prednisone; Vincristine | 1981 |
Growth and differentiation patterns of human acute non lymphoid leukemia in diffusion chambers before and after treatment.
Topics: Acute Disease; Adolescent; Adult; Aged; Animals; Cell Differentiation; Cells, Cultured; Child; Culture Techniques; Cytarabine; Daunorubicin; Female; Humans; Leukemia; Male; Methylprednisolone; Mice; Middle Aged; Thioguanine | 1981 |
Intensified remission induction therapy for acute nonlymphocytic leukemia (ANLL). Treatment report on 60 patients.
Topics: Acute Disease; Adolescent; Adult; Aged; Cytarabine; Daunorubicin; Humans; Leukemia; Middle Aged; Thioguanine; Thrombocytopenia | 1981 |
Management of patients with acute non-lymphocytic leukemia who fail first cycle of induction therapy.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Agents; Bone Marrow; Cell Count; Cytarabine; Doxorubicin; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Middle Aged; Prednisone; Prognosis; Thioguanine; Time Factors; Vincristine | 1981 |
Determination of cytarabine and uracil arabinoside in human plasma and cerebrospinal fluid by high-performance liquid chromatography.
Topics: Arabinofuranosyluracil; Chromatography, High Pressure Liquid; Cytarabine; Humans; Leukemia; Time Factors; Uridine | 1981 |
Central nervous system toxicity of high-dose systemic cytosine arabinoside.
Topics: Adolescent; Adult; Aged; Brain; Brain Diseases; Cerebellar Ataxia; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Leukemia; Male; Middle Aged; Purkinje Cells | 1981 |
[Treatment of acute leukemia with newly synthesized N4-behenoyl-l-beta-D-arabinofuranosylcytosine (BH-AC) (author's transl)].
Topics: Acute Disease; Adolescent; Adult; Aged; Cytarabine; Drug Evaluation; Female; Humans; Leukemia; Male; Middle Aged | 1981 |
Clinical implications of cytokinetic and biochemical features of acute leukemia cells.
Topics: Acute Disease; Cell Transformation, Neoplastic; Cytarabine; Daunorubicin; Humans; Leukemia; Prednisolone; Thioinosine | 1980 |
Phase III study of N4-behenoyl-l-beta-D-arabinofuranosylcytosine in adult acute leukemia-BH-AC-DMP therapy.
Topics: Acute Disease; Adolescent; Adult; Cytarabine; Daunorubicin; Female; Humans; Leukemia; Male; Middle Aged; Prednisolone; Thioinosine | 1980 |
Mechanism of action of antileukemic agents: inhibition of DNA polymerases.
Topics: Animals; Cattle; Cytarabine; Daunorubicin; DNA Polymerase I; DNA Polymerase II; Doxorubicin; Guanosine; Leukemia; Nucleic Acid Synthesis Inhibitors; Thionucleosides | 1980 |
Combination chemotherapy with daunorubicin, cytosine arabinoside and prednisolone (DAP) in acute nonlymphocytic leukemia.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Child; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Middle Aged; Prednisolone | 1981 |
Remission-induction regimens in acute nonlymphocytic leukemia.
Topics: Aged; Cytarabine; Daunorubicin; Drug Administration Schedule; Humans; Leukemia; Middle Aged; Thioguanine | 1980 |
Prediction of chemotherapy response in human leukemia using an in vitro chemotherapy sensitivity test on the leukemic colony-forming cells.
Topics: Adult; Aged; Antineoplastic Agents; Cell Survival; Cells, Cultured; Cytarabine; Daunorubicin; Doxorubicin; Female; Hematopoietic Stem Cells; Humans; Leukemia; Male; Middle Aged; Prednisone; Vincristine | 1980 |
[DCTP and DCMP two step therapy in acute non-lymphocytic leukemia (author's transl)].
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Agents; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia; Middle Aged; Prednisolone; Thioguanine; Thioinosine | 1980 |
[Intraventricular chemotherapy for treatment of meningeal dissemination from malignant neoplasms (author's transl)].
Topics: Antineoplastic Agents; Cytarabine; Hydrocortisone; Injections, Intraventricular; Leukemia; Lymphoma; Meningeal Neoplasms; Methotrexate; Neoplasm Invasiveness | 1980 |
Intensive five-drug combination chemotherapy for adult acute non-lymphocytic leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Agents; Arrhythmias, Cardiac; Cytarabine; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Heart Failure; Humans; Leukemia; Male; Middle Aged; Prednisone; Prognosis; Remission, Spontaneous; Thioguanine; Vincristine | 1980 |
Male fertility during chemotherapy for acute leukemia.
Topics: Acute Disease; Adult; Cytarabine; Daunorubicin; Female; Fertility; Humans; Leukemia; Male; Pregnancy; Thioguanine | 1980 |
A simple rapid autoradiography for 3H-thymidine labeling index and its application to therapy of adult acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Autoradiography; Cell Cycle; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged; Thymidine; Tritium | 1980 |
In vivo cellular kinetic and pharmacological studies of 1-beta-D-arabinofuranosylcytosine and 3-deazauridine chemotherapy for relapsing acute leukemia.
Topics: 3-Deazauridine; Adolescent; Adult; Aged; Cell Cycle; Cytarabine; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Metabolic Clearance Rate; Middle Aged; Uridine | 1981 |
Ara-C lung: noncardiogenic pulmonary edema complicating cytosine arabinoside therapy of leukemia.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Cytarabine; Female; Humans; Infant; Leukemia; Lung; Male; Middle Aged; Pulmonary Edema | 1981 |
Evaluation of the cytotoxic activity of gemcitabine in primary cultures of tumor cells from patients with hematologic or solid tumors.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Breast Neoplasms; Cisplatin; Cladribine; Colorectal Neoplasms; Cytarabine; Deoxycytidine; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Female; Gemcitabine; Humans; In Vitro Techniques; Leukemia; Lung Neoplasms; Lymphoma; Ribonucleotide Reductases; Tumor Cells, Cultured; Urogenital Neoplasms | 1995 |
[Successful collection of peripheral blood stem cells mobilized by a combination of G-CSF with high-dose Ara-C or high-dose etoposide].
Topics: Acute Disease; Adolescent; Adult; Blood Component Removal; Cytarabine; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Lymphoma, Non-Hodgkin; Male; Middle Aged | 1993 |
Comparative genotoxicity of 2,3'-O-cyclocytidine, beta-xylocytidine and 1-beta-D-arabinofuranosylcytosine in human tumor cell lines.
Topics: Ancitabine; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cell Survival; Child; Cytarabine; Cytidine; DNA Damage; DNA Repair; DNA Replication; DNA, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Leukemia; Neoplasms; Tumor Cells, Cultured | 1994 |
Characterization of enriched CD34+ cells from healthy volunteers and those from patients treated with chemotherapy plus granulocyte colony-stimulating factor (G-CSF).
Topics: Adult; Antigens, CD; Antigens, CD34; Antigens, Differentiation, Myelomonocytic; Bone Marrow Cells; CD13 Antigens; Cell Separation; Colony-Forming Units Assay; Cytarabine; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Leukemia; Lymphoma; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-kit; Receptor Protein-Tyrosine Kinases; Receptors, Colony-Stimulating Factor; Sialic Acid Binding Ig-like Lectin 3 | 1995 |
Cellular pharmacology of N4-hexadecyl-1-beta-D-arabinofuranosylcytosine in the human leukemic cell lines K-562 and U-937.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Arabinofuranosylcytosine Triphosphate; Cell Differentiation; Cytarabine; Dipyridamole; DNA; Drug Carriers; Drug Interactions; Half-Life; Humans; Leukemia; Liposomes; Tumor Cells, Cultured | 1995 |
Functional hyperactivity of monocytes after bone marrow transplantation: possible relevance for the development of post-transplant complications or relapse.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Biopterins; Bone Marrow Transplantation; Busulfan; Carmustine; Cells, Cultured; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Disease Susceptibility; Female; Graft vs Host Disease; Hepatic Veno-Occlusive Disease; Humans; Leukemia; Lymphoma; Male; Melphalan; Middle Aged; Monocytes; Neopterin; Podophyllotoxin; Respiratory Burst; Superoxides; Tumor Necrosis Factor-alpha; Whole-Body Irradiation | 1995 |
[Hypoplastic leukemia achieved long-term remission with low-dose cytosine arabinoside].
Topics: Aged; Anemia; Cytarabine; Female; Humans; Leukemia; Leukopenia; Remission Induction | 1995 |
Unrelated bone marrow donor transplants for children with leukemia or myelodysplasia.
Topics: Actuarial Analysis; Adolescent; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cyclophosphamide; Cyclosporine; Cytarabine; Disease-Free Survival; Female; Graft vs Host Disease; Hepatic Veno-Occlusive Disease; Histocompatibility; Humans; Infections; Leukemia; Lung Diseases, Interstitial; Male; Methylprednisolone; Myelodysplastic Syndromes; Retrospective Studies; Risk Factors; Survival Analysis; Tissue Donors; Treatment Outcome; Whole-Body Irradiation; Wisconsin | 1995 |
Viridans streptococcal bacteraemia in patients with neutropenia.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Bacteremia; Case-Control Studies; Cytarabine; Environment, Controlled; Female; Humans; Leukemia; Lymphoma; Male; Middle Aged; Mouth; Neutropenia; Prospective Studies; Risk Factors; Saliva; Streptococcal Infections; Streptococcus | 1995 |
Collection and transplantation of peripheral blood stem cells in very small children weighting 20 kg or less.
Topics: Antineoplastic Combined Chemotherapy Protocols; Blood Component Removal; Blood Preservation; Body Weight; Bone Marrow Diseases; Carboplatin; Catheterization, Central Venous; Catheters, Indwelling; Child, Preschool; Cisplatin; Colony-Forming Units Assay; Combined Modality Therapy; Contraindications; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Female; Graft Survival; Hematopoietic Stem Cell Transplantation; Humans; Infant; Leukemia; Male; Neoplasms; Platelet Transfusion; Retrospective Studies; Safety | 1995 |
Intracellular pharmacodynamic studies of the synergistic combination of 6-mercaptopurine and cytosine arabinoside in human leukemia cell lines.
Topics: Arabinofuranosylcytosine Triphosphate; Cell Division; Cell Survival; Cytarabine; Deoxycytidine Kinase; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Resistance; Drug Synergism; Humans; Kinetics; Leukemia; Mercaptopurine; Tumor Cells, Cultured | 1995 |
Antileukemic activity studies and cellular pharmacology of the analogues of 2-hydroxy-1H-isoindole-1,3-dione (HISD) alone and in combination with cytosine arabinoside (ara-C) against human leukemia cells CEM/0.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; DNA, Neoplasm; Humans; Indoles; Leukemia; Tumor Cells, Cultured | 1994 |
A novel microculture kinetic assay (MiCK assay) for malignant cell growth and chemosensitivity.
Topics: Animals; Cell Count; Cell Division; Cytarabine; Drug Screening Assays, Antitumor; Humans; Hydrogen-Ion Concentration; Kinetics; Leukemia; Mice; Optics and Photonics; Tumor Cells, Cultured | 1994 |
Acute leukemia coexpressing myeloid, B- and T-lineage associated markers: multiparameter analysis of criteria defining lineage commitment and maturational stage in a case of undifferentiated leukemia.
Topics: Acute Disease; Antigens, CD; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Marrow; Cytarabine; Daunorubicin; Fatal Outcome; Female; Hematopoietic Cell Growth Factors; Humans; Immunophenotyping; Leukemia; Middle Aged; Mitoxantrone; Neoplastic Stem Cells; Remission Induction; Thioguanine; Tumor Stem Cell Assay | 1995 |
Cytosine arabinoside and mitoxantrone treatment of relapsed or refractory childhood leukemia: initial response and relationship to multidrug resistance gene 1.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Carrier Proteins; Child; Child, Preschool; Cytarabine; Drug Evaluation; Drug Resistance; Female; Gene Expression; Humans; Infant; Leukemia; Leukemia, Myeloid, Acute; Male; Membrane Glycoproteins; Mitoxantrone; Molecular Sequence Data; Polymerase Chain Reaction; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction | 1994 |
[Therapeutic effects of peripheral blood stem cell transplantation following combination chemotherapy using ranimustine, cytarabine, etoposide and cyclophosphamide for patients with hematological malignancies].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Lymphoma; Male; Middle Aged; Nitrosourea Compounds | 1994 |
Itraconazole in leukemic patients with invasive aspergillosis (IA): impact on intensive chemotherapy completion.
Topics: Adult; Aspergillosis; Cytarabine; Daunorubicin; Humans; Itraconazole; Leukemia; Male; Middle Aged | 1994 |
Characterization of newly established adriamycin resistant human leukemic cell lines (KY-ADR1 and KY-ADR2).
Topics: Antibodies, Monoclonal; Antigens, CD; Antigens, Surface; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Division; Cell Line; Cytarabine; Doxorubicin; Drug Resistance; Gene Expression; Growth Substances; Humans; Interleukin-1; Kinetics; Leukemia; Thymidine; Tumor Cells, Cultured | 1994 |
[Mitoxantrone-aracytine with or without quinine in the treatment of refractory or relapsed acute leukemia].
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged; Mitoxantrone; Quinine; Recurrence | 1994 |
2 chlorodeoxyadenosine activity and cross resistance patterns in primary cultures of human hematologic neoplasms.
Topics: Cladribine; Cytarabine; Doxorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Humans; Leukemia; Lymphoma, Non-Hodgkin; Mechlorethamine; Multiple Myeloma; Protein Binding; Tumor Cells, Cultured; Vincristine | 1993 |
[Neutropenic typhlitis: a frequently missed complication of aplasia-inducing tumor therapy with a possible association to the combination of etoposide with high-dose cytosine-arabinoside].
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Synergism; Enterocolitis, Pseudomembranous; Etoposide; Female; Humans; Leukemia; Male; Neutropenia; Retrospective Studies | 1994 |
[The use of diflucan in myelotoxic agranulocytosis].
Topics: Acute Disease; Adult; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Candidiasis; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Evaluation; Female; Fluconazole; Humans; Leukemia; Prednisolone; Vincristine | 1993 |
Resistance to cytosine arabinoside in acute leukemia: the significance of mutations in CTP synthetase.
Topics: Acute Disease; Adult; Carbon-Nitrogen Ligases; Cytarabine; DNA Mutational Analysis; Drug Resistance; Humans; Leukemia; Ligases; Mutation; Tumor Cells, Cultured | 1994 |
Report from the 34th annual meeting of the American Society of Hematology, December 4-8, 1992.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interferon-alpha; Leukemia; Lymphoma, Non-Hodgkin; Medical Oncology; Multiple Myeloma; Societies, Medical | 1993 |
[Pharmacodynamics and action mechanism of antitumor agents].
Topics: Antineoplastic Agents; Blood Transfusion; Cytarabine; DNA Damage; DNA Repair; Humans; Leukemia; Neoplasms | 1993 |
The ileocecal syndrome in acute leukemia--is thrombosis an important part of pathogenesis?
Topics: Cytarabine; Enterocolitis, Pseudomembranous; Humans; Leukemia; Neutropenia; Thrombosis | 1993 |
Synthesis and testing of new antileukemic Schiff bases of N-hydroxy-N'-aminoguanidine against CCRF-CEM/0 human leukemia cells in vitro and synergism studies with cytarabine (Ara-C).
Topics: Antineoplastic Agents; Cell Division; Cytarabine; Drug Screening Assays, Antitumor; Drug Synergism; Guanidines; Humans; Isoquinolines; Leukemia; Oxidation-Reduction; Schiff Bases; Tumor Cells, Cultured | 1993 |
Role of total body irradiation as based on the comparison of preparation regimens for allogeneic bone marrow transplantation for acute leukemia in first complete remission.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Etoposide; Female; Humans; Infant; Japan; Leukemia; Male; Methotrexate; Nimustine; Proportional Hazards Models; Radiotherapy Dosage; Remission Induction; Transplantation, Homologous; Whole-Body Irradiation | 1993 |
Induction of surface antigen recognized by new monoclonal antibody, YU311, on 1-beta-D-arabinofuranosylcytosine-resistant human leukemic cell line.
Topics: Animals; Antibodies, Monoclonal; Antigens, CD; Antigens, Surface; Cell Line; Cytarabine; Drug Resistance; Flow Cytometry; Immunoblotting; Immunophenotyping; Leukemia; Membrane Proteins; Mice; Mice, Inbred BALB C; Tumor Cells, Cultured | 1993 |
Pneumocystis carinii pneumonia in adults with acute leukaemia: is there a need for primary chemoprophylaxis?
Topics: Aclarubicin; Acute Disease; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cohort Studies; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Etoposide; Female; Finland; Humans; Immunocompromised Host; Incidence; Leukemia; Male; Mercaptopurine; Methotrexate; Middle Aged; Mitoxantrone; Pneumonia, Pneumocystis; Prednisone; Premedication; Retrospective Studies; Thioguanine; Trimethoprim, Sulfamethoxazole Drug Combination; Vincristine | 1996 |
Modulation of metabolism and cytotoxicity of cytosine arabinoside with N-(phosphon)-acetyl-L-aspartate in human leukemic blast cells and cell lines.
Topics: Antimetabolites, Antineoplastic; Arabinofuranosylcytosine Triphosphate; Aspartic Acid; Cytarabine; Cytidine Triphosphate; DNA, Neoplasm; Drug Screening Assays, Antitumor; HL-60 Cells; Humans; Leukemia; Phosphonoacetic Acid; Tumor Cells, Cultured; Uridine Triphosphate | 1996 |
Combination chemotherapy of carboplatin and cytosine arabinoside for high-risk leukemia: a pilot study.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged; Neutropenia; Pilot Projects; Remission Induction; Risk Factors; Thrombocytopenia | 1995 |
Central nervous system relapse after bone marrow transplantation for acute leukemia in first remission.
Topics: Actuarial Analysis; Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cerebrospinal Fluid; Child, Preschool; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Disease-Free Survival; Female; Humans; Hydrocortisone; Injections, Spinal; Leukemia; Leukemic Infiltration; Male; Meninges; Methotrexate; Prospective Studies; Recurrence; Remission Induction; Risk; Transplantation, Homologous; Treatment Outcome; Whole-Body Irradiation | 1996 |
Analysis of bases, nucleosides, and (oligo)nucleotides by capillary electrophoresis.
Topics: Capillary Action; Cytarabine; DNA; Drug Monitoring; Electrophoresis; Humans; Leukemia; Lymphocytes; Nucleosides; Nucleotides; Oligonucleotides; Purines; Pyrimidines; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 1996 |
Interaction of cyclin-dependent kinase 2 and the Lyn tyrosine kinase in cells treated with 1-beta-D-arabinofuranosylcytosine.
Topics: Antimetabolites, Antineoplastic; CDC2-CDC28 Kinases; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Cyclins; Cytarabine; Enzyme Activation; Humans; Immunoblotting; Leukemia; Membrane Proteins; Nuclear Proteins; Phosphorylation; Platelet-Derived Growth Factor; Precipitin Tests; Protein Serine-Threonine Kinases; Recombinant Fusion Proteins; src-Family Kinases; Subcellular Fractions; Tumor Cells, Cultured; Tyrosine | 1996 |
[CD7, HLA-DR, CD38 positive acute undifferentiated leukemia with subcutaneous tumor and thymoma].
Topics: Acute Disease; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Antigens, CD; Antigens, CD7; Antigens, Differentiation; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Etoposide; Gene Rearrangement; HLA-DR Antigens; Humans; Immunoglobulin Heavy Chains; Immunophenotyping; Leukemia; Membrane Glycoproteins; Mitoxantrone; N-Glycosyl Hydrolases; Prednisolone; Receptors, Antigen, T-Cell, gamma-delta; Remission Induction; Skin Neoplasms; Thymoma; Thymus Neoplasms | 1996 |
Acute polyneuropathy after high dose cytosine arabinoside in patients with leukemia.
Topics: Acute Disease; Adult; Antimetabolites, Antineoplastic; Cerebellar Diseases; Cytarabine; Demyelinating Diseases; Female; Humans; Leukemia; Male; Middle Aged; Peripheral Nervous System Diseases; Retrospective Studies | 1996 |
Effects of cytosine arabinoside on human leukemia cells.
Topics: Aged; Cell Line; Chromatography, High Pressure Liquid; Cytarabine; Humans; Leukemia; Male; Tumor Cells, Cultured | 1996 |
Seeking the nucleoside transporter.
Topics: Animals; Antimetabolites, Antineoplastic; Carrier Proteins; Cell Membrane; Cladribine; Cloning, Molecular; Cytarabine; Deoxycytidine; Erythrocytes; Gemcitabine; Glucose Transporter Type 1; Humans; Leukemia; Lymphoma; Membrane Proteins; Monosaccharide Transport Proteins; Nucleosides; Oocytes; Recombinant Proteins; Uridine; Vidarabine; Xenopus | 1997 |
Induction of apoptosis by camptothecin and topotecan.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Bone Marrow; Camptothecin; Cell Cycle; Cytarabine; DNA Damage; Enzyme Inhibitors; HL-60 Cells; Humans; Leukemia; Topotecan | 1996 |
NONMEM population pharmacokinetic studies of cytosine arabinoside after high-dose and after loading bolus followed by continuous infusion of the drug in pediatric patients with leukemias.
Topics: Adolescent; Adult; Arabinofuranosyluracil; Child; Child, Preschool; Chromatography, High Pressure Liquid; Cytarabine; Half-Life; Humans; Infant; Infusions, Intravenous; Leukemia; Metabolic Clearance Rate; Models, Biological | 1996 |
[Involvement of ICE/CED 3 family proteases in antitumor agent-induced apoptosis].
Topics: Antineoplastic Agents; Apoptosis; Camptothecin; Caspase 1; Cycloheximide; Cysteine Endopeptidases; Cytarabine; Doxorubicin; Humans; Leukemia; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1997 |
Study of the apoptosis induced in vitro by antitumoral drugs on leukaemic cells.
Topics: Acute Disease; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Cell Cycle; Cytarabine; Daunorubicin; Drug Screening Assays, Antitumor; Flow Cytometry; Humans; Idarubicin; Kinetics; Leukemia; Mitoxantrone | 1997 |
Autologous bone marrow purging by in situ IL-2 activation of endogenous killer cells.
Topics: Bone Marrow Purging; Bone Marrow Transplantation; Breast Neoplasms; Colony-Forming Units Assay; Cytarabine; Cytotoxicity, Immunologic; Daunorubicin; Drug Resistance, Neoplasm; Etoposide; Female; Hematopoietic Stem Cells; HL-60 Cells; Humans; Interleukin-2; Killer Cells, Lymphokine-Activated; Killer Cells, Natural; Leukemia; Lung Neoplasms; Lymphocyte Activation; Tissue Donors; Transplantation, Autologous; Transplantation, Homologous; Tumor Cells, Cultured | 1997 |
Differential incorporation of ara-C, gemcitabine, and fludarabine into replicating and repairing DNA in proliferating human leukemia cells.
Topics: Antineoplastic Agents; Binding Sites; Cytarabine; Deoxycytidine; DNA Repair; DNA Replication; DNA, Neoplasm; Gemcitabine; Humans; Leukemia; Tumor Cells, Cultured; Vidarabine | 1997 |
Sensitivity of acute leukemia cells to cytarabine is a correlate of cellular es nucleoside transporter site content measured by flow cytometry with SAENTA-fluorescein.
Topics: Acute Disease; Adenosine; Affinity Labels; Antimetabolites, Antineoplastic; Carrier Proteins; Cell Death; Cytarabine; Flow Cytometry; Fluorescein; Fluoresceins; Humans; Leukemia; Nucleosides; Thionucleosides; Tumor Cells, Cultured | 1997 |
Allogeneic bone marrow transplantation for children with acute leukemia: long-term follow-up of patients prepared with high-dose cytosine arabinoside and fractionated total body irradiation.
Topics: Acute Disease; Adolescent; Adult; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Follow-Up Studies; Graft Survival; Humans; Infant; Leukemia; Myelodysplastic Syndromes; Transplantation, Homologous; Treatment Outcome; Whole-Body Irradiation | 1997 |
Pharmacokinetics of high-dose cytarabine and its deamination product--a reappraisal.
Topics: Acute Disease; Adult; Aged; Antimetabolites, Antineoplastic; Arabinofuranosyluracil; Cytarabine; Deamination; Dose-Response Relationship, Drug; Female; Humans; Leukemia; Male; Middle Aged; Myelodysplastic Syndromes | 1997 |
Techniques of magna-field irradiation.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Clinical Protocols; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dose Fractionation, Radiation; Drug Administration Schedule; Humans; Leukemia; Transplantation Conditioning; Whole-Body Irradiation | 1983 |
Bcr-Abl exerts its antiapoptotic effect against diverse apoptotic stimuli through blockage of mitochondrial release of cytochrome C and activation of caspase-3.
Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspases; Cysteine Endopeptidases; Cytarabine; Cytochrome c Group; Enzyme Activation; Etoposide; Fusion Proteins, bcr-abl; Humans; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Promyelocytic, Acute; Membrane Potentials; Mitochondria; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Sphingolipids; Transfection; Tumor Cells, Cultured | 1998 |
Follicular mucinosis as a presenting sign of acute myeloblastic leukemia.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cytarabine; Doxorubicin; Follow-Up Studies; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Mucinosis, Follicular; Mycosis Fungoides; Paraneoplastic Syndromes; Remission Induction; Skin Neoplasms; T-Lymphocytes | 1998 |
Regulation of deoxycytidine kinase by deoxycytidine and deoxycytidine 5' triphosphate in whole leukemia and tumor cells.
Topics: Animals; Arabinofuranosylcytosine Triphosphate; CHO Cells; Cricetinae; Cytarabine; Deoxycytidine; Deoxycytidine Kinase; Deoxycytosine Nucleotides; HL-60 Cells; Homeostasis; Humans; Leukemia; Ribonucleotide Reductases; Tumor Cells, Cultured | 1998 |
Activation of deoxycytidine kinase by various nucleoside analogues.
Topics: Adenine Nucleotides; Antimetabolites, Antineoplastic; Arabinonucleosides; Cell Cycle; Cells, Cultured; Cladribine; Clofarabine; Cytarabine; Deoxycytidine Kinase; Enzyme Activation; HL-60 Cells; Humans; Leukemia; Lymphocytes; Palatine Tonsil; Thymidine Kinase; Tumor Cells, Cultured; Vidarabine | 1998 |
Different effects of an oligonucleotide uptake stimulating protein on leukemic cells in their primitive and differentiated state.
Topics: Biological Transport; Cell Differentiation; Cell Division; Cytarabine; DNA-Binding Proteins; Fungal Proteins; Gene Transfer Techniques; Granulocytes; HL-60 Cells; Humans; Hydroxyurea; Leukemia; Leukocytes, Mononuclear; Oligodeoxyribonucleotides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1998 |
Case 17: Essential thrombocythaemia with inversion 3 terminating in acute leukaemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Chromosome Inversion; Chromosomes, Human, Pair 3; Cytarabine; Etoposide; Fatal Outcome; Female; Humans; Karyotyping; Leukemia; Middle Aged; Mitoxantrone; Thrombocythemia, Essential | 1998 |
p53 may mediate the mdr-1 expression via the WT1 gene in human vincristine-resistant leukemia/lymphoma cell lines.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p16; Cytarabine; DNA-Binding Proteins; Doxorubicin; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Genes, p53; Genes, Retinoblastoma; Humans; Leukemia; Lymphoma; Multidrug Resistance-Associated Proteins; Proto-Oncogene Proteins c-myc; RNA, Messenger; RNA, Neoplasm; Transcription Factors; Tumor Cells, Cultured; Vincristine; WT1 Proteins | 1998 |
Augmentation of 1-beta-D-arabinofuranosylcytosine (Ara-C) cytotoxicity in leukaemia cells by co-administration with antisignalling drugs.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Cytarabine; HL-60 Cells; Humans; Leukemia; Ribonucleotide Reductases | 1998 |
Human leukemic K562 cells treated with cytosine arabinoside: enhancement of erythroid differentiation by retinoic acid and retinol.
Topics: Antimetabolites, Antineoplastic; Cell Differentiation; Cytarabine; Drug Synergism; Erythropoiesis; Humans; K562 Cells; Keratolytic Agents; Leukemia; Tretinoin; Vitamin A | 1998 |
Haemopoietic cell transplantation activity and results: a single institution experience.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cytarabine; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Histocompatibility Testing; Humans; Hungary; Leukemia; Melphalan; Podophyllotoxin; Recurrence; Transplantation Conditioning; Transplantation, Autologous; Treatment Outcome; Whole-Body Irradiation | 1998 |
Re: V.I. Avramis et al., Pharmacokinetic and pharmacodynamic studies of fludarabine and cytosine arabinoside administered as loading boluses followed by continuous infusions after a Phase I/II study in pediatric patients with relapsed leukemias. Clin. Can
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Cytarabine; Humans; Leukemia; Terminology as Topic; Vidarabine; Vidarabine Phosphate | 1999 |
Signaling defect in the activation of caspase-3 and PKCdelta in human TUR leukemia cells is associated with resistance to apoptosis.
Topics: Apoptosis; Caspase 3; Caspases; Cytarabine; Enzyme Activation; Etoposide; Humans; Isoenzymes; Leukemia; Nucleic Acid Synthesis Inhibitors; Protein Kinase C; Protein Kinase C-delta; Signal Transduction; Tumor Cells, Cultured; U937 Cells | 1999 |
Early detection by ultrasound scan of severe post-chemotherapy gut complications in patients with acute leukemia.
Topics: Acute Disease; Adult; Anti-Infective Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dilatation, Pathologic; Enterocolitis; Etoposide; Female; Gallbladder Diseases; Gastrointestinal Diseases; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Intubation, Gastrointestinal; Leukemia; Leukemia, Myelomonocytic, Acute; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Neutropenia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome; Ultrasonography | 1999 |
Chemotherapy and donor peripheral blood progenitor cells for acute leukemia in early relapse after allogeneic bone marrow transplantation.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Etoposide; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Mitoxantrone; Recurrence; Time Factors; Tissue Donors; Transplantation Chimera; Transplantation, Homologous | 1999 |
Cyclophosphamide, cytosine arabinoside and TBI as a conditioning regimen for allogeneic bone marrow transplantation in patients with leukemia.
Topics: Adolescent; Adult; Bone Marrow Transplantation; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Female; Graft vs Host Disease; Hepatic Veno-Occlusive Disease; Humans; Leukemia; Male; Middle Aged; Prospective Studies; Recurrence; Transplantation Conditioning; Transplantation, Homologous; Whole-Body Irradiation | 1999 |
Exonucleases and the incorporation of aranucleotides into DNA.
Topics: Animals; Cattle; Chromatography; Cytarabine; Cytidine Monophosphate; DNA; DNA Polymerase gamma; DNA Repair; DNA Replication; DNA-Directed DNA Polymerase; Electrophoresis, Polyacrylamide Gel; Exodeoxyribonucleases; HL-60 Cells; Humans; Kinetics; Leukemia; Recombinant Proteins; Thymus Gland; Time Factors; Tissue Inhibitor of Metalloproteinases | 1999 |
Inhibition of protein kinase C activator-mediated induction of p21CIP1 and p27KIP1 by deoxycytidine analogs in human leukemia cells: relationship to apoptosis and differentiation.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Bryostatins; Cell Cycle Proteins; Cell Differentiation; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Cytarabine; Deoxycytidine; Drug Interactions; Enzyme Activation; Gemcitabine; Humans; Lactones; Leukemia; Macrolides; Microtubule-Associated Proteins; Mitogens; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Suppressor Proteins; U937 Cells | 1999 |
Pharmacokinetics of anticancer drugs in vitro.
Topics: Amino Acids; Antineoplastic Agents; Asparaginase; Cyclophosphamide; Cytarabine; Etoposide; HL-60 Cells; Humans; Leukemia; Tumor Cells, Cultured | 1999 |
[Evaluation of cytarabine-induced apoptosis in leukemic cell lines; utility of annexin V method].
Topics: Annexin A5; Apoptosis; Cytarabine; Enzyme Inhibitors; HL-60 Cells; Humans; K562 Cells; Leukemia; Methods; U937 Cells | 1999 |
Bcl-2, bax and bcl-xL expression in human sensitive and resistant leukemia cell lines.
Topics: Annexin A5; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; bcl-2-Associated X Protein; bcl-X Protein; Blotting, Western; Cytarabine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Flow Cytometry; Gene Expression; HL-60 Cells; Humans; Inhibitory Concentration 50; Leukemia; Microscopy, Fluorescence; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured; Vault Ribonucleoprotein Particles | 1999 |
FLAG (fludarabine, high-dose cytarabine and G-CSF) for refractory and high-risk relapsed acute leukemia in children.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Leukemia; Recurrence; Risk Factors; Vidarabine | 2000 |
Comparison of DiOC(6)(3) uptake and annexin V labeling for quantification of apoptosis in leukemia cells and non-malignant T lymphocytes from children.
Topics: Annexin A5; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Carbocyanines; Child; Cytarabine; Daunorubicin; Flow Cytometry; Fluorescent Dyes; HL-60 Cells; Humans; Indicators and Reagents; Leukemia; Propidium; T-Lymphocytes; Tumor Cells, Cultured; U937 Cells; Vincristine | 2000 |
Nonionic surfactant vesicles (niosomes) of cytarabine hydrochloride for effective treatment of leukemias: encapsulation, storage, and in vitro release.
Topics: Antimetabolites, Antineoplastic; Chemistry, Pharmaceutical; Cytarabine; Delayed-Action Preparations; Humans; Leukemia; Surface-Active Agents | 2000 |
Post-translational modifications of eukaryotic initiation factor-5A (eIF-5A) as a new target for anti-cancer therapy.
Topics: Antineoplastic Agents; Cell Cycle; Cell Death; Chelating Agents; Cytarabine; Deferoxamine; Epidermal Growth Factor; ErbB Receptors; Eukaryotic Translation Initiation Factor 5A; Exotoxins; Humans; Interferon-gamma; Iron; Kinetics; Leukemia; Lysine; Oropharyngeal Neoplasms; Peptide Initiation Factors; Protein Processing, Post-Translational; RNA-Binding Proteins; Transforming Growth Factor alpha; Tumor Cells, Cultured | 1999 |
Enhanced cytotoxic effect of Ara-C by low intensity ultrasound to HL-60 cells.
Topics: Antimetabolites, Antineoplastic; Cell Death; Cytarabine; HL-60 Cells; Humans; Leukemia; Neoplasms; Ultrasonic Therapy | 2000 |
In vitro leukemia cell models of Ara-C resistance.
Topics: Antimetabolites, Antineoplastic; Cytarabine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Gene Expression Regulation, Neoplastic; Humans; Leukemia; Oligodeoxyribonucleotides, Antisense; Polymerase Chain Reaction; Tumor Cells, Cultured | 2000 |
Palliative cytoreduction in refractory acute leukemia: a retrospective study of 57 adult patients.
Topics: Acute Disease; Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Diarrhea; Female; Humans; Injections, Intravenous; Injections, Subcutaneous; Leukemia; Leukocyte Count; Male; Mercaptopurine; Methotrexate; Middle Aged; Nausea; Palliative Care; Retrospective Studies; Stomatitis; Thioguanine | 2000 |
Lung toxicity following fludarabine, cytosine arabinoside and mitoxantrone (flan) treatment for acute leukemia.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Hemorrhage; Humans; Infant, Newborn; Leukemia; Leukemia, Myeloid, Acute; Lung Diseases; Male; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Respiratory Distress Syndrome, Newborn; Staphylococcal Infections; Vidarabine | 2000 |
Potentiation of 1-beta-D-arabinofuranosylcytosine-mediated mitochondrial damage and apoptosis in human leukemia cells (U937) overexpressing bcl-2 by the kinase inhibitor 7-hydroxystaurosporine (UCN-01).
Topics: Alkaloids; Antineoplastic Agents; Apoptosis; Cytarabine; Drug Synergism; Enzyme Inhibitors; Humans; Leukemia; Mitochondria; Protein Kinase C; Proto-Oncogene Proteins c-bcl-2; Staurosporine; U937 Cells | 2000 |
Antileukemic drugs increase death receptor 5 levels and enhance Apo-2L-induced apoptosis of human acute leukemia cells.
Topics: Acute Disease; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Apoptotic Protease-Activating Factor 1; BH3 Interacting Domain Death Agonist Protein; Carrier Proteins; Caspase 3; Caspase 8; Caspase 9; Caspases; Cytarabine; Cytochrome c Group; Doxorubicin; Etoposide; HL-60 Cells; Humans; Jurkat Cells; Leukemia; Membrane Glycoproteins; Proteins; Proto-Oncogene Proteins c-bcl-2; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53; U937 Cells; Up-Regulation | 2000 |
Chemotherapy and marrow transplantation for congenital leukaemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Etoposide; Female; Humans; Infant, Newborn; Leukemia; Methotrexate; Mitoxantrone; Prednisolone; Treatment Outcome; Vincristine | 2001 |
Action of topoisomerase targeting drugs on non-Hodgkin's lymphoma and leukemia. Correlation of clinical and cell culture studies.
Topics: Acute Disease; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase I as Topic; Cytarabine; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA-Binding Proteins; DNA, Neoplasm; Enzyme Inhibitors; Etoposide; Humans; Isoenzymes; Leukemia; Leukocytes; Lymphoma, Non-Hodgkin; Mitoxantrone; Polymerase Chain Reaction; RNA, Messenger; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Topotecan | 2000 |
Combination chemotherapy of intermediate-dose cytarabine, idarubicin, plus etoposide and subsequent mobilized donor leukocyte infusion for relapsed acute leukemia after allogeneic bone marrow transplantation.
Topics: Actuarial Analysis; Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Disease-Free Survival; Etoposide; Female; Graft vs Host Disease; Hematopoietic Stem Cell Mobilization; Humans; Idarubicin; Leukemia; Leukocyte Transfusion; Male; Recurrence; Survival Rate; Transplantation, Homologous | 2001 |
Potential protective effects of melatonin on bone marrow of rats exposed to cytotoxic drugs.
Topics: Acid Phosphatase; Adjuvants, Immunologic; Alkaline Phosphatase; Animals; Bone Marrow Cells; Cell Survival; Corticosterone; Cytarabine; Erythrocyte Count; Hemoglobins; Immunosuppressive Agents; Leukemia; Leukocyte Count; Male; Melatonin; Rats; Rats, Sprague-Dawley; Serum Albumin; Serum Globulins; Thiobarbituric Acid Reactive Substances | 1998 |
Respiratory chain-generated oxidative stress following treatment of leukemic blasts with DNA-damaging agents.
Topics: Apoptosis; Ceramides; Cytarabine; Digitonin; DNA Damage; Electron Transport; Electron Transport Complex III; Etoposide; Gamma Rays; Leukemia; Mitochondria; Nucleic Acid Synthesis Inhibitors; Oxidative Stress; Permeability; Reactive Oxygen Species; Thioredoxins; Tumor Cells, Cultured | 2001 |
In vitro cytotoxic effects of a tyrosine kinase inhibitor STI571 in combination with commonly used antileukemic agents.
Topics: Antineoplastic Agents; Apoptosis; Benzamides; Cytarabine; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Enzyme Inhibitors; Fusion Proteins, bcr-abl; Harringtonines; Homoharringtonine; Humans; Hydroxyurea; Imatinib Mesylate; Interferon-alpha; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Methotrexate; Microbial Sensitivity Tests; Neoplasm Proteins; Neoplasms; Piperazines; Pyrimidines; Tumor Cells, Cultured; Vincristine | 2001 |
Increased sensitivity to cytosine arabinoside in human leukemia by c-raf-1 antisense oligonucleotides.
Topics: Antimetabolites, Antineoplastic; Blotting, Northern; Cell Division; Cytarabine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; K562 Cells; Leukemia; Oligonucleotides, Antisense; Proto-Oncogene Proteins c-raf; Signal Transduction; U937 Cells | 2001 |
Effect of granulocyte colony-stimulating factor on chemotherapeutic activity of cytosine arabinoside in acute leukemic cell lines.
Topics: Acute Disease; Antineoplastic Agents; Apoptosis; Cell Count; Cell Division; Cytarabine; Drug Synergism; Flow Cytometry; Granulocyte Colony-Stimulating Factor; Humans; Leukemia; Tumor Cells, Cultured | 2001 |
Imbalanced DNA synthesis induced by cytosine arabinoside and fludarabine in human leukemia cells.
Topics: Antineoplastic Agents; Cytarabine; DNA Replication; DNA, Neoplasm; Humans; Leukemia; Tumor Cells, Cultured; Vidarabine | 2001 |
Fludarabine and cytarabine as a sequential infusion regimen for treatment of adults with recurrent, refractory or poor prognosis acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Cytarabine; Cytogenetic Analysis; Disease-Free Survival; Drug Administration Schedule; Female; Hematologic Diseases; Humans; Infections; Infusion Pumps; Leukemia; Lung Diseases; Male; Middle Aged; Nervous System Diseases; Prognosis; Recurrence; Retrospective Studies; Survival Rate; Treatment Outcome; Vidarabine | 2001 |
The widening role of statins: RAS signal transduction and drug-induced cytotoxicity in human leukemia: a commentary to 'interaction of cytosine arabinoside and lovastatin in human leukemia cells'.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Synergism; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leukemia; Lovastatin; ras Proteins | 2001 |
Leukemia cutis in an elderly patient treated with low dose cytosine arabinoside and etoposide.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Etoposide; Exanthema; Humans; Immunophenotyping; Leukemia; Leukemia, Myeloid, Acute; Male | 2001 |
Differential effects of the MDR1 (multidrug resistance) gene-activating agents on protein kinase C: evidence for redundancy of mechanisms of acquired MDR in leukemia cells.
Topics: Ceramides; Cytarabine; Drug Resistance, Multiple; Enzyme Activation; Gene Expression Regulation; Genes, MDR; Humans; Leukemia; Protein Kinase C; Second Messenger Systems; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation | 2000 |
Reversal of cytosine arabinoside (ara-C) resistance by the synergistic combination of 6-thioguanine plus ara-C plus PEG-asparaginase (TGAP) in human leukemia lines lacking or expressing p53 protein.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Asparaginase; Cytarabine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; HL-60 Cells; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, T-Cell; Polyethylene Glycols; Proto-Oncogene Proteins c-bcl-2; Thioguanine; Tumor Cells, Cultured; Tumor Suppressor Protein p53; U937 Cells | 2001 |
Selective protection of mitogenically stimulated human lymphocytes but not leukemic cells from cytosine arabinoside-induced apoptosis by LY294002, a phosphoinositol-3 kinase inhibitor.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Blotting, Western; Cell Cycle; Cell Division; Chromones; Cyclins; Cytarabine; Enzyme Activation; Enzyme Inhibitors; Flow Cytometry; Humans; Immunoenzyme Techniques; Leukemia; Lymphocytes; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Phytohemagglutinins; Poly(ADP-ribose) Polymerases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Tumor Cells, Cultured; Up-Regulation | 2001 |
Mechanisms of uptake and resistance to troxacitabine, a novel deoxycytidine nucleoside analogue, in human leukemic and solid tumor cell lines.
Topics: Amino Acid Sequence; Antineoplastic Agents; Biological Transport; Carrier Proteins; Cytarabine; Cytidine Deaminase; Cytosine; Deoxycytidine; Deoxycytidine Kinase; Dioxolanes; Drug Resistance, Neoplasm; Gemcitabine; Humans; Leukemia; Male; Membrane Proteins; Molecular Sequence Data; Nucleoside Transport Proteins; Phosphorylation; Prostatic Neoplasms; Sequence Homology, Amino Acid; Sodium; Stereoisomerism; Tritium; Tumor Cells, Cultured; Uridine | 2001 |
In vitro effects of dexrazoxane (Zinecard) and classical acute leukemia therapy: time to consider expanded clinical trials?
Topics: Acute Disease; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Cell Death; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Humans; Inhibitory Concentration 50; Leukemia; Mitoxantrone; Razoxane; Tumor Cells, Cultured | 2001 |
Selection of drug-resistant transduced cells with cytosine nucleoside analogs using the human cytidine deaminase gene.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Bone Marrow Cells; Colony-Forming Units Assay; Cytarabine; Cytidine Deaminase; Decitabine; Deoxycytidine; DNA Modification Methylases; Drug Evaluation; Drug Resistance; Enzyme Inhibitors; Flow Cytometry; Gene Transfer Techniques; Genetic Vectors; Green Fluorescent Proteins; Humans; Leukemia; Luminescent Proteins; Retroviridae; Transgenes | 2001 |
Treatment of relapse after allogeneic bone marrow transplantation with reduced intensity conditioning (FLAG +/- Ida) and second allogeneic stem cell transplant.
Topics: Acute Disease; Adult; Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Disease-Free Survival; Female; Filgrastim; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia; Leukemia, Myeloid; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recombinant Proteins; Recurrence; Reoperation; Retrospective Studies; Survival Rate; Transplantation Conditioning; Transplantation, Homologous; Vidarabine | 2001 |
Standard versus alternative myeloablative conditioning regimens in allogeneic hematopoietic stem cell transplantation for high-risk acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Busulfan; Child; Child, Preschool; Cyclophosphamide; Cyclosporine; Cytarabine; Disease-Free Survival; Etoposide; Female; Graft Survival; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Immunosuppressive Agents; Infant; Leukemia; Life Tables; Male; Methylprednisolone; Middle Aged; Premedication; Retrospective Studies; Risk; Survival Analysis; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Whole-Body Irradiation | 2002 |
Bryostatin 1 increases 1-beta-D-arabinofuranosylcytosine-induced cytochrome c release and apoptosis in human leukemia cells ectopically expressing Bcl-x(L).
Topics: Antineoplastic Agents; Apoptosis; bcl-X Protein; Bryostatins; Cytarabine; Cytochrome c Group; Drug Interactions; Humans; Lactones; Leukemia; Macrolides; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured | 2002 |
Oral manifestations of acute myelomonocytic leukemia: a case report and review of the classification of leukemias.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Fatal Outcome; Gingival Hemorrhage; Gingival Overgrowth; Humans; Idarubicin; Leukemia; Leukemia, Myelomonocytic, Acute; Male; Middle Aged | 2002 |
[Diagnostic image (92). A man with fever during chemotherapy. Invasive pulmonary mycosis].
Topics: Amphotericin B; Antibiotics, Antineoplastic; Antifungal Agents; Antimetabolites, Antineoplastic; Cytarabine; Fever; Humans; Idarubicin; Leukemia; Lung; Lung Diseases, Fungal; Male; Middle Aged; Radiography | 2002 |
Bone marrow transplantation with intensive combination chemotherapy/radiation therapy (SCARI) in acute leukemia.
Topics: Adolescent; Adult; Bone Marrow Cells; Bone Marrow Transplantation; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Graft vs Host Reaction; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Thioguanine; Time Factors; Transplantation, Homologous | 1977 |
Acute leukemia in children: experience in Saskatchewan in 1966-72.
Topics: Acute Disease; Adolescent; Antineoplastic Agents; Blood Transfusion; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Follow-Up Studies; Hematopoietic Stem Cells; Humans; Leukemia; Leukemia, Lymphoid; Palliative Care; Prednisone; Saskatchewan; Vincristine | 1975 |
[New drugs for the therapy of acute leukemia].
Topics: Acute Disease; Antineoplastic Agents; Azacitidine; Cytarabine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Guanazole; Humans; Leukemia; Lomustine; Peptichemio; Podophyllotoxin; Razoxane; Zinostatin | 1975 |
Deoxycytidine kinase: properties of the enzyme from human leukemic granulocytes.
Topics: Azacitidine; Blood Proteins; Cell Separation; Cell-Free System; Cytarabine; Cytidine Deaminase; Deoxycytidine; Granulocytes; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Molecular Weight; Phosphates; Phosphotransferases; Tissue Extracts; Uridine Kinase | 1975 |
[Experiences with polychemotherapy of acute leukemias in adults with special reference to the COAP combination].
Topics: Acute Disease; Adolescent; Adult; Aged; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Middle Aged; Prednisone; Vincristine | 1975 |
Serum vitamin B12-binding proteins in a case of eosinophilic leukemia.
Topics: Adult; Alpha-Globulins; Beta-Globulins; Cyclophosphamide; Cytarabine; Eosinophils; Humans; Leukemia; Male; Prednisone; Protein Binding; Remission, Spontaneous; Vincristine; Vitamin B 12 | 1975 |
Biochemical pharmacology of cytidine analog metabolism in human leukemic cells.
Topics: Acute Disease; Adolescent; Adult; Aged; Azacitidine; Cytarabine; Cytidine Deaminase; Humans; In Vitro Techniques; Leukemia; Middle Aged; Phosphotransferases; Uridine Kinase | 1975 |
The therapy of acute leukemia in the adult: a progress report.
Topics: Acute Disease; Adult; Antineoplastic Agents; Azacitidine; Blood Transfusion; Cytarabine; Daunorubicin; Dexamethasone; Etoposide; Granulocytes; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Patient Isolation; Platelet Transfusion; Pneumonia; Prednisone; Pyrimethamine; Remission, Spontaneous; Thioguanine; Vincristine; Zinostatin | 1976 |
[Chemotherapy of acute leukemia with cyclocytidine, with special reference to serum ara-C deaminase activity (author's transl)].
Topics: Acute Disease; Adolescent; Adult; Aged; Aminohydrolases; Ancitabine; Antineoplastic Agents; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged; Remission, Spontaneous | 1977 |
Cytarabine and leukaemia remission.
Topics: Cytarabine; Drug Resistance; Humans; Leukemia; Prognosis; Remission, Spontaneous | 1978 |
Acute eosinophilic leukemia. An ultrastructural study.
Topics: Adult; Bone Marrow; Cytarabine; Daunorubicin; Eosinophils; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Prednisone; Recurrence | 1978 |
Treatment of acute nonlymphocytic leukemia (ANLL) in elderly patients. Results of a multicentric study.
Topics: Acute Disease; Aged; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Middle Aged; Remission, Spontaneous; Thioguanine | 1979 |
Effects of 5-fluorodeoxyuridine on cell viability and uptake of deoxycytidine and (3H)cytosine arabinoside in L5178Y cells.
Topics: Animals; Cells, Cultured; Cytarabine; Deoxycytidine; DNA; Floxuridine; Kinetics; Leukemia; Mice; RNA | 1976 |
Clinical application of bone marrow culture from patients with acute leukemia.
Topics: Acute Disease; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Cytarabine; Humans; Leukemia; Methods | 1976 |
Occurrence of BK virus and BK virus-specific antibodies in the urine of patients receiving chemotherapy for malignancy.
Topics: Adolescent; Adult; Aged; Animals; Antibodies, Viral; BK Virus; Child; Child, Preschool; Chlorocebus aethiops; Cyclophosphamide; Cytarabine; Cytopathogenic Effect, Viral; Daunorubicin; Drug Therapy, Combination; Erythrocytes; Fluorescent Antibody Technique; Hemagglutination Inhibition Tests; Humans; Immunosuppression Therapy; Kidney; Leukemia; Middle Aged; Polyomavirus; Prednisone; Simian virus 40; Urine; Vincristine; Virus Cultivation | 1975 |
On the mode of decrease of leukemic cells during treatment of acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aminobiphenyl Compounds; Antineoplastic Agents; Asparaginase; Bone Marrow; Cell Survival; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Leukocyte Count; Male; Mercaptopurine; Mesylates; Methotrexate; Middle Aged; Neutrophils; Prednisolone; Time Factors; Zinostatin | 1976 |
Sister chromatid exchange studies for monitoring DNA damage and repair capacity after cytostatics in vitro and in lymphocytes of leukaemic patients under cytostatic therapy.
Topics: Antineoplastic Agents; Busulfan; Cells, Cultured; Chlorambucil; Chromatids; Crossing Over, Genetic; Cyclophosphamide; Cytarabine; DNA Repair; Erythritol; Humans; Leukemia; Lymphocytes; Mesylates; Mitomycins; Vincristine | 1978 |
Heparin lock: how, what, why.
Topics: Adult; Cyclophosphamide; Cytarabine; Heparin; Humans; Infusions, Parenteral; Leukemia; Male | 1979 |
Current concepts in acute leukemia.
Topics: Acute Disease; Adult; Age Factors; BCG Vaccine; Cytarabine; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Humans; Leukemia; Leukemia, Myeloid, Acute; Middle Aged; Prednisone; Vincristine | 1977 |
Multiple-drug chemotherapy for acute leukemia The TRAMPCOL regimen: results in 86 patients.
Topics: Adolescent; Asparaginase; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Methotrexate; Prednisolone; Remission, Spontaneous; Thioguanine; Vincristine | 1977 |
Adult acute leukemia: frequency of central system involvement in long term survivors.
Topics: Adolescent; Adult; Brain Neoplasms; Cytarabine; Female; Follow-Up Studies; Humans; Leukemia; Leukemia, Lymphoid; Male; Meningeal Neoplasms; Methotrexate; Recurrence; Remission, Spontaneous; Time Factors | 1977 |
[Results and problems in the treatment of childhood leukaemia (author's transl)].
Topics: Age Factors; Child; Cytarabine; Daunorubicin; Humans; Hungary; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Prednisolone; Thioguanine; Vincristine | 1978 |
Maintenance therapy of adult acute nonlymphoblastic leukemia: an argument against the need for central nervous system prophlyaxis.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission, Spontaneous; Thioguanine | 1978 |
Therapy of acute nonlymphocytic leukemia: I. Clinical aspects.
Topics: Acute Disease; Aged; Blood Transfusion; Cytarabine; Daunorubicin; Doxorubicin; Female; Humans; Leukemia; Male; Middle Aged; Pancytopenia | 1979 |
[Therapy of acute nonlymphocytic leukemia: 2. Biological characteristics and prediction of response].
Topics: Acute Disease; Age Factors; Cytarabine; Daunorubicin; Doxorubicin; Humans; Infections; Leukemia | 1979 |
[Occurrence of infectious complications during therapy for acute leukemia].
Topics: Antineoplastic Agents; Bacterial Infections; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Neutropenia; Prednisone; Thioguanine | 1979 |
Serial studies on in vitro colony formation in patients with acute leukemia in relation to the maintenance of remission.
Topics: Acute Disease; Adult; Child; Colony-Forming Units Assay; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisolone; Remission, Spontaneous | 1978 |
Meningeal involvement in leukemias and malignant lymphomas of adults: incidence, course of disease, and treatment for prevention.
Topics: Adult; Cytarabine; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma; Meningeal Neoplasms; Methotrexate; Prognosis; Retrospective Studies; Time Factors | 1979 |
Prognostic value of colony-stimulating and colony-forming cells in peripheral blood in acute non-lymphoblastic leukemia.
Topics: Adult; Aged; Cell Division; Cells, Cultured; Clone Cells; Colony-Stimulating Factors; Cytarabine; Daunorubicin; Female; Humans; Leukemia; Leukemia, Myeloid, Acute; Leukocyte Count; Leukocytes; Male; Middle Aged; Prognosis; Remission, Spontaneous | 1977 |
Kinetics of inhibition of deoxynucleotide-polymerizing enzyme activities from normal and leukemic human cells by 9-beta-D-arabinofuranosyladenine 5'-triphosphate and 1-beta-D-arabinofuranosylcytosine 5'-triphosphate.
Topics: B-Lymphocytes; Cell Line; Cytarabine; DNA Nucleotidyltransferases; Kinetics; Leukemia; Nucleic Acid Synthesis Inhibitors; T-Lymphocytes; Vidarabine | 1977 |
Biochemical determinants for antileukemia drug treatment.
Topics: Adenosine Deaminase; Adenosine Deaminase Inhibitors; Arabinofuranosylcytosine Triphosphate; Coformycin; Cytarabine; Humans; Leukemia; Methotrexate; Pentostatin; Phosphorylation; Tissue Distribution | 1979 |
ABO blood group system and bone marrow transplantation.
Topics: ABO Blood-Group System; Adolescent; Adult; Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Cells; Bone Marrow Transplantation; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Graft Rejection; Graft vs Host Disease; Histocompatibility; Humans; Immunosuppression Therapy; Isoantibodies; Leukemia; Male; Thioguanine; Transplantation Immunology; Transplantation, Homologous | 1977 |
Approaches to leukemic relapse following bone marrow transplantation.
Topics: Adolescent; Adult; Bone Marrow Transplantation; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Graft vs Host Disease; HLA Antigens; Humans; Leukemia; Middle Aged; Mycoses; Neoplasm Recurrence, Local; Thioguanine; Transplantation, Homologous | 1978 |
Aggressive therapy in acute respiratory failure from leukemic pulmonary infiltrates.
Topics: Acute Disease; Adult; Cytarabine; Doxorubicin; Female; Humans; Leukemia; Lung Neoplasms; Oxygen; Respiration, Artificial; Respiratory Insufficiency | 1979 |
Continuous intravenous arabinosyl cytosine infusions delivered by a new portable infusion system.
Topics: Acute Disease; Adolescent; Adult; Aged; Ambulatory Care; Cytarabine; Evaluation Studies as Topic; Humans; Infusions, Parenteral; Leukemia; Middle Aged; Safety; Time Factors | 1979 |
The use of cell kinetics in the development of drug combinations.
Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Division; Cell Separation; Cell Survival; Cytarabine; DNA, Neoplasm; Drug Administration Schedule; Drug Therapy, Combination; Humans; Kinetics; Leukemia; Models, Biological; Multiple Myeloma; Neoplasms | 1979 |
Remission induction and remission maintenance in adult acute nonlymphocytic leukemia employing a modified cytostatic (COAP) regimen.
Topics: Acute Disease; Adolescent; Adult; Aged; Cyclophosphamide; Cytarabine; Female; Humans; Leukemia; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Time Factors; Vincristine | 1979 |
Daunorubicin, cytosine arabinoside and 6-thioguanine (DAT) combination chemotherapy for the treatment of acute non-lymphocytic leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Agents; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Middle Aged; Thioguanine | 1979 |
High dose cytosine arabinoside (HDARAC) in refractory acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Agents; Central Nervous System; Child; Child, Preschool; Cytarabine; Digestive System; Drug Resistance; Female; Humans; Infusions, Parenteral; Leukemia; Male; Middle Aged; Remission, Spontaneous; Time Factors | 1979 |
[Results of treating acute nonlymphoblastic leukaemia in adults (author's transl)].
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Cytarabine; Daunorubicin; Female; Humans; Leukemia; Male; Middle Aged | 1979 |
[Varicella infections in children with acute leukemia (author's transl)].
Topics: Acute Disease; Adolescent; Age Factors; Chickenpox; Child; Child, Preschool; Cytarabine; Female; Humans; Leukemia; Male | 1979 |
Remission induction in acute nonlymphocytic leukemia: comparison of a seven-day and ten-day infusion of cytosine arabinoside in combination with adriamycin.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Cytarabine; Doxorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Middle Aged; Remission, Spontaneous; Time Factors | 1979 |
[Tests of cell mediated immunity during the treatment of acute leukemia in infants (author's transl)].
Topics: Acute Disease; Adolescent; Child; Child, Preschool; Cytarabine; Daunorubicin; Humans; Immune Adherence Reaction; Immunity, Cellular; Infant; Leukemia; Mercaptopurine; Prednisolone; Vincristine | 1977 |
Antimetabolites in the central nervous system.
Topics: Animals; Antimetabolites, Antineoplastic; Central Nervous System; Central Nervous System Diseases; Cytarabine; Humans; Injections, Spinal; Leukemia; Methotrexate | 1977 |
Treatment of meningeal neoplasms.
Topics: Adult; Animals; Antineoplastic Agents; Brain Neoplasms; Carcinoma 256, Walker; Catheterization; Child; Cytarabine; Disease Models, Animal; Drug Therapy, Combination; Humans; Injections, Intraventricular; Injections, Spinal; Leukemia; Lumbosacral Region; Meninges; Methotrexate; Rats; Spinal Cord Neoplasms | 1977 |
Restoration of the bone marrow pluripotent stem cells in AKR mice after arabinosylcytosine treatment.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Cytarabine; Female; Leukemia; Mice; Mice, Inbred AKR; Organ Size; Spleen; Stimulation, Chemical; Thymus Gland | 1977 |
Treating acute nonlymphocytic leukemia.
Topics: Acute Disease; Aged; Anemia; Antineoplastic Agents; Bacterial Infections; Blood Transfusion; Cytarabine; Drug Therapy, Combination; Hemorrhage; Humans; Leukemia; Middle Aged; Mycoses; Remission, Spontaneous | 1978 |
Acute leukemia in pregnancy. Successful delivery after cytarabine and doxorubicin.
Topics: Acute Disease; Adult; Cesarean Section; Cytarabine; Doxorubicin; Female; Humans; Leukemia; Pregnancy; Pregnancy Complications, Hematologic; Remission, Spontaneous | 1978 |
[Progressive pulmonary fibrosis during combination chemotherapy with BCNU (author's transl)].
Topics: Acute Disease; Carmustine; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia; Middle Aged; Pulmonary Fibrosis | 1978 |
[A case of leukemia obtained complete remission after delivery (author's transl)].
Topics: Acute Disease; Adult; Cytarabine; Daunorubicin; Female; Humans; Leukemia; Prednisolone; Pregnancy; Pregnancy Complications, Hematologic; Remission, Spontaneous; Vincristine | 1978 |
[Treatment results of therapy resistant acute leukemias with 7 cystostatic agents (TRAMPCO-scheme)].
Topics: Acute Disease; Adolescent; Adult; Aged; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Resistance; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Methotrexate; Middle Aged; Prednisolone; Thioguanine; Vincristine | 1978 |
Cytosine arabinoside induced gastrointestinal toxic alterations in sequential chemotherapeutic protocols: a clinical-pathologic study of 33 patients.
Topics: Antineoplastic Agents; Bone Marrow; Cell Cycle; Cytarabine; Digestive System; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Humans; Infections; Infusions, Parenteral; Intestinal Mucosa; Kidney; Leukemia; Male; Serum Albumin; Water-Electrolyte Imbalance | 1978 |
Cytosine arabinoside modulation of the mitotic index in treatment of adult acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged; Mitosis; Mitotic Index | 1978 |
Rapid remission induction in adult acute non-lymphoblastic leukaemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Cytarabine; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Humans; Leukemia; Male; Middle Aged; Podophyllotoxin; Remission, Spontaneous; Sepsis; Time Factors | 1978 |
[Therapeutic results in adult acute non-lymphoblastic leukemia].
Topics: Acute Disease; Adult; Cytarabine; Daunorubicin; Female; Humans; Leukemia; Male | 1978 |
[Therapeutic results in patients with acute leukemia].
Topics: Acute Disease; Adolescent; Adult; Blood Platelets; Blood Transfusion; Cytarabine; Daunorubicin; Humans; Leukemia; Middle Aged; Prognosis | 1978 |
Further local experience in the treatment of acute non-lymphoblastic leukaemia.
Topics: Acute Disease; Adult; Aged; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia; Middle Aged; Prednisone; Thioguanine; Vincristine | 1978 |
Perspectives and prospectives in the management of acute leukemia.
Topics: BCG Vaccine; Cytarabine; Daunorubicin; Humans; Immunotherapy; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Life Expectancy; Mycobacterium bovis; Nucleotides, Cyclic; Prednisone; Remission, Spontaneous; Vincristine | 1976 |
Advances in the management of acute nonlymphocytic leukemia.
Topics: Acute Disease; Anti-Bacterial Agents; Blood Transfusion; Cytarabine; Daunorubicin; Drug Therapy, Combination; Granulocytes; Hemorrhage; Humans; Immunotherapy; Infection Control; Infections; Kidney Diseases; Leukemia; Platelet Transfusion; Transplantation, Homologous | 1976 |
[Adverse effects and complications of intensive therapy of acute leukemia in adults using the OAP scheme (oncovin, cytosine arabinoside, prednisolone)].
Topics: Acute Disease; Adult; Cytarabine; Drug Therapy, Combination; Humans; Leukemia; Prednisolone; Vincristine | 1977 |
Continuous drug delivery methods reflect progress in therapy for chronic diseases.
Topics: Aged; Chronic Disease; Cytarabine; Dosage Forms; Drug Implants; Glaucoma; Humans; Injections, Intravenous; Leukemia; Levodopa; Neoplasms; Parkinson Disease; Pilocarpine; Research | 1977 |
Treatment of acute nonlymphocytic leukemia in elderly patients: a prospective study of intensive chemotherapy.
Topics: Acute Disease; Aged; Antineoplastic Agents; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Infections; Length of Stay; Leukemia; Male; Middle Aged; Prednisone; Prospective Studies; Remission, Spontaneous; Thioguanine; Time Factors | 1977 |
Treatment of acute nonlymphoblastic leukemia in children with a multiple-drug protocol.
Topics: Acute Disease; Adolescent; Antineoplastic Agents; Asparaginase; Child; Child, Preschool; Cytarabine; Doxorubicin; Drug Therapy, Combination; Female; Humans; Infant; Leukemia; Male; Meningeal Neoplasms; Remission, Spontaneous; Thioguanine | 1977 |
Chemotherapy for adult acute nonlymphocytic leukemia with daunorubicin and cytosine arabinoside.
Topics: Acute Disease; Adolescent; Adult; Aged; Central Nervous System Diseases; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Meningeal Neoplasms; Middle Aged; Neoplasm Metastasis; Remission, Spontaneous; Time Factors | 1977 |
[Varicella-zoster virus infections. Course, virologic findings and therapeutic trials in healthy and in immunologic disease children].
Topics: Chickenpox; Child; Child, Preschool; Cytarabine; Herpes Zoster; Humans; Infant; Leukemia | 1976 |
[Cytostatic therapy in haemoblastoses].
Topics: Asparaginase; Cytarabine; Daunorubicin; Doxorubicin; Humans; Leukemia; Mercaptopurine; Methotrexate; Prednisolone; Thioguanine; Vincristine | 1976 |
Clinical studies of beta-thioguanine deoxyriboside alone and in combination with arabinosyl cytosine.
Topics: Acute Disease; Adolescent; Adult; Aged; Child; Child, Preschool; Cytarabine; Deoxyguanosine; Deoxyribonucleosides; Drug Therapy, Combination; Female; Guanosine; Humans; Leukemia; Leukopenia; Male; Middle Aged; Neoplasm Metastasis; Neoplasms; Remission, Spontaneous; Thioguanine; Thionucleosides; Thrombocytopenia; Time Factors | 1976 |
Early responses to chemotherapy detected by pulse cytophotometry.
Topics: Adult; Antineoplastic Agents; Asparaginase; Bone Marrow; Bone Marrow Cells; Cell Division; Child; Cytarabine; DNA, Neoplasm; Doxorubicin; Fluorometry; Humans; Leukemia; Lymphoma, Non-Hodgkin; Melphalan; Prednisone; Vincristine | 1976 |
Preventing central nervous system leukemia.
Topics: Animals; Brain; Central Nervous System Diseases; Child; Child, Preschool; Cytarabine; Humans; Hydrocortisone; Injections, Spinal; Leukemia; Methotrexate; Recurrence; Spine; Time Factors | 1976 |
Maintenance of remission in adult acute nonlymphoblastic leukemia using intermittent courses of cytosine arabinoside (NSC-63878) and 6-thioguanine (NSC-752).
Topics: Acute Disease; Adolescent; Adult; Aged; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Middle Aged; Remission, Spontaneous; Thioguanine | 1976 |
The effect of cytosine arabinoside on platelet aggregation.
Topics: Acute Disease; Cytarabine; Humans; In Vitro Techniques; Leukemia; Platelet Aggregation; Remission, Spontaneous | 1976 |
[Pretherapeutic sensitivity tests of human leukemia cells against cytostatic drugs in vitro in relation to the in vivo effects].
Topics: Antineoplastic Agents; Cell Transformation, Neoplastic; Cytarabine; Daunorubicin; Humans; In Vitro Techniques; Leukemia; Thymidine | 1976 |
[Personal experience with the treatment of infantile acute leukemia with cytosine-arabinoside].
Topics: Adolescent; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Drug Evaluation; Drug Therapy, Combination; Humans; Infant; Leukemia; Prednisone; Thioguanine | 1976 |
Treatment of meningeal leukemia.
Topics: Catheterization; Central Nervous System Diseases; Child; Child, Preschool; Cytarabine; Drug Therapy, Combination; Female; Humans; Hydrocortisone; Injections, Intraventricular; Injections, Spinal; Leukemia; Methotrexate | 1976 |
Occurrence of hepatitis and hepatitis B surface antigen in adult patients with acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Blood Transfusion; Cyclophosphamide; Cytarabine; Female; Follow-Up Studies; Hepatitis; Hepatitis B Antigens; Humans; Immunoelectrophoresis; Leukemia; Leukemia, Lymphoid; Male; Middle Aged; Nitrosourea Compounds; Radioimmunoassay; Remission, Spontaneous; Statistics as Topic; Vincristine | 1975 |
[In vitro study of sensitivity of leukemic cells to cytotoxic drugs (anticytogram)].
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Agents; Asparaginase; Carbon Radioisotopes; Cells, Cultured; Cyclophosphamide; Cytarabine; Daunorubicin; Depression, Chemical; Humans; In Vitro Techniques; Leukemia; Leukemia, Lymphoid; Mercaptopurine; Middle Aged; Monomethylhydrazine; Prednisolone; Remission, Spontaneous; Thymidine; Tritium; Uridine; Vincristine | 1975 |
Drugs five years later: cytarabine.
Topics: Acute Disease; Adult; Animals; Bone Marrow Diseases; Central Nervous System Diseases; Cyclophosphamide; Cytarabine; Daunorubicin; DNA, Neoplasm; Drug Therapy, Combination; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma; Prednisone; Remission, Spontaneous; Thioguanine; Vincristine; Virus Diseases | 1975 |
Cell kinetics and practical consequences for therapy of acute leukemia.
Topics: Adrenal Cortex Hormones; Asparaginase; Bone Marrow; Bone Marrow Cells; Cell Division; Cells, Cultured; Cytarabine; Daunorubicin; DNA; DNA, Neoplasm; Drug Therapy, Combination; Humans; Kinetics; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate; Mitosis; Prognosis; Vincristine | 1975 |
Cyclocytidine study in the treatment of acute leukemia.
Topics: Cytarabine; Drug Evaluation; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Prednisolone | 1975 |
Non-Hodgkin's lymphoma in children: results of treatment with LSA2-L2 protocol.
Topics: Adolescent; Antineoplastic Agents; Asparaginase; Bone Neoplasms; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Leukemia; Leukemia, Lymphoid; Lymph Nodes; Lymphoma; Male; Mediastinal Neoplasms; Methotrexate; Nasopharyngeal Neoplasms; Ovarian Neoplasms; Skin Neoplasms; Stomach Neoplasms; Thioguanine; Vincristine | 1975 |
[Results of combined chemotherapy in treatment-resistant leukaemia of adults (author's transl)].
Topics: Acute Disease; Adolescent; Adult; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia; Leukemia, Myeloid, Acute; Methotrexate; Middle Aged; Prednisone; Remission, Spontaneous; Thioguanine; Time Factors; Vincristine | 1975 |
Cytokinetics of human acute leukemia before and after chemotherapy.
Topics: Adolescent; Adult; Asparaginase; Bone Marrow; Bone Marrow Cells; Cell Division; Cells, Cultured; Child; Cytarabine; DNA, Neoplasm; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphocytes; Male; Thioguanine; Thymidine | 1975 |
Chronic neurologic disturbance in childhood leukemia.
Topics: Adolescent; Antineoplastic Agents; Child; Cyclophosphamide; Cytarabine; Folic Acid; Humans; Learning Disabilities; Leukemia; Leukemia, Lymphoid; Methotrexate; Movement Disorders; Nervous System Diseases; Prospective Studies; Radiotherapy; Seizures; Time Factors | 1976 |
Correlation of response to 1-beta-D-arabinofuranosyl cytosine and metabolism of drug by tumor.
Topics: Cytarabine; Cytosine Nucleotides; Deamination; Female; Hemangiopericytoma; Humans; Leukemia; Leukemia, Myeloid; Melanoma; Middle Aged; Neoplasms; Neoplastic Cells, Circulating; Oxidative Phosphorylation; Splenic Neoplasms | 1976 |
Usefulness of cytosine arabinoside (NSC-63878) and prednisone (NSC-10023) in refractory childhood lymphoblastic leukemia.
Topics: Bone Marrow; Bone Marrow Cells; Child; Cytarabine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Leukemia; Leukemia, Lymphoid; Prednisone; Remission, Spontaneous | 1976 |
Serial quantitative observations of leukemic and normal hematopoietic cells in the bone marrow of acute leukemia under chemotherapy.
Topics: Bone Marrow; Bone Marrow Cells; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Prednisolone; Remission, Spontaneous; Vincristine | 1976 |
Combinations of arabinosyl cytosine and 6-thioguanine for treatment of adults with acute leukemia.
Topics: Adolescent; Adult; Aged; Bone Marrow; Cytarabine; DNA; Drug Therapy, Combination; Female; Hematopoietic Stem Cells; Humans; Injections, Intravenous; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission, Spontaneous; Thioguanine | 1975 |
Treatment of adult acute non-lymphoblastic leukemia using intermittent combination chemotherapy with daunomycin, cytosine arabinoside, 6-mercaptopurine and prednisolone-DCMP two step therapy.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisolone; Remission, Spontaneous | 1976 |
Aids in the management of leukemia (cellremoval by continuous flow leukapheresis and impulsecytophotometry).
Topics: Blood Cell Count; Blood Cells; Blood Platelets; Bone Marrow; Bone Marrow Cells; Cell Division; Cell Separation; Cytarabine; DNA; Doxorubicin; Erythrocytes; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Thioguanine | 1976 |
Treatment of adult acute non-lymphocytic leukemia.
Topics: Acute Disease; Adolescent; Adult; Cytarabine; Humans; Leukemia; Middle Aged; Remission, Spontaneous; Thioguanine | 1975 |
Letter: Epipodophyllotoxin VP 16213 in acute non-lymphoblastic leukaemia.
Topics: Cytarabine; Doxorubicin; Drug Therapy, Combination; Humans; Leukemia; Podophyllotoxin; Thiophenes | 1975 |
Growth kinetics of solid tumors. Implications for chemotherapy.
Topics: Acute Disease; Adenocarcinoma; Animals; Antineoplastic Agents; Cell Division; Colonic Neoplasms; Culture Techniques; Cytarabine; DNA; Humans; Kinetics; Leukemia; Meiosis; Melanoma; Mitosis; Neoplasms; Neoplasms, Experimental; Rats; Thymidine; Tritium; Vinblastine | 1975 |
[Models of polychemotherapy in acute leukemias].
Topics: Acute Disease; Antineoplastic Agents; Asparaginase; Carmustine; Cyclophosphamide; Cytarabine; Dacarbazine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia; Mercaptopurine; Thioguanine | 1975 |
Mechanism of action of cyclocytidine in leukemic cells.
Topics: Cells, Cultured; Cytarabine; DNA, Neoplasm; Humans; Leukemia | 1975 |
[Cytosine arabinoside in the treatment of acute leukemia in children].
Topics: Acute Disease; Age Factors; Child; Cytarabine; Drug Evaluation; Humans; Leukemia | 1975 |
[Treatment of leukemia (author's transl)].
Topics: Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia | 1975 |
[New quadruple combination intermittent therapy (cyclocytidine, adriamycin, 6MP and prednisolone: CyAMP) for adult acute leukemia (author's transl)].
Topics: Acute Disease; Adult; Aged; Cytarabine; Doxorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Mercaptopurine; Middle Aged; Prednisolone | 1975 |
[Cell cycle effect of cytosine arabinoside, vincristine, and massive leukapheresis on human leukemic blasts and its application to a quadruple combination chemotherapy of acute leukemia (author's transl)].
Topics: Acute Disease; Adult; Blood Transfusion; Bone Marrow; Bone Marrow Cells; Cytarabine; DNA, Neoplasm; Drug Therapy, Combination; Female; Humans; Leukemia; Leukocytes; Male; Mitosis; Vincristine | 1975 |
[A new quadruple combination chemotherapy (Neo-DCMP) in acute leukemia (author's transl)].
Topics: Acute Disease; Adult; Child; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia; Mercaptopurine; Middle Aged; Prednisolone | 1975 |
[Quadruple combination chemotherapy of acute leukemia using daunomycin, cytosine arabinoside, vincristine and prednisolone (author's transl)].
Topics: Acute Disease; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia; Prednisolone; Vincristine | 1975 |
[Diagnosis and therapy of neoplastic meningosis].
Topics: Acute Disease; Central Nervous System Diseases; Cytarabine; Humans; Injections, Spinal; Leukemia; Meninges; Methotrexate; Mitolactol; Neoplasm Metastasis; Nitrosourea Compounds; Pyrimethamine; Radiotherapy | 1975 |
Clincal pharmacology of O2,2'-cyclocytidine.
Topics: Administration, Oral; Anhydrides; Antineoplastic Agents; Cytarabine; Deamination; Half-Life; Humans; Hydrolysis; Injections, Intramuscular; Injections, Intravenous; Injections, Spinal; Injections, Subcutaneous; Leukemia; Neoplasms; Time Factors | 1975 |
The role of cytosine arabinoside maintenance in acute nonlymphoblastic leukemia.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Bone Marrow Diseases; Child; Cytarabine; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Leukemia; Middle Aged; Muramidase; Prednisone; Vincristine | 1975 |
Letter: Treatment of acute leukaemia.
Topics: Acute Disease; Cytarabine; Doxorubicin; Drug Therapy, Combination; Humans; Leukemia; Methotrexate; Podophyllotoxin | 1975 |
Cytosine arabinoside and cranial irradiation in the treatment of meningeal leukemia.
Topics: Adult; Brain Diseases; Cobalt Radioisotopes; Cytarabine; Humans; Leukemia; Male | 1975 |
[Significance of the synchronization of the leukemic cell population in the therapy of patients with acute leukemia].
Topics: Antimetabolites, Antineoplastic; Bone Marrow; Bone Marrow Cells; Cytarabine; Evaluation Studies as Topic; Humans; Leukemia; Mercaptopurine; Methotrexate; Mitosis; Prednisolone; Time Factors; Vincristine | 1975 |
[Method of administration and inactivation of cytosine arabinoside in acute leukemia].
Topics: Acute Disease; Cytarabine; Humans; Leukemia | 1975 |
[First clinical experiences with a modified COAP schedule in acute leukoses of adults].
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Humans; Leukemia; Middle Aged; Prednisone; Vincristine | 1975 |
[Chemotherapy with cytosine arabinoside, daunomycin and vincristine in refractory leukemia of childhood (author's transl)].
Topics: Adolescent; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Infant; Leukemia; Male; Vincristine | 1975 |
[Treatment of central nervous system leukemia in acute childhood leukemia. I. Results of intrathecal single or multiple drug combination therapy (author's transl)].
Topics: Acute Disease; Central Nervous System Diseases; Child; Child, Preschool; Cytarabine; Drug Therapy, Combination; Female; Humans; Hydrocortisone; Infant; Injections, Spinal; Leukemia; Male; Methotrexate | 1975 |
[Number and kinds of drug side-effects in a medical clinic (author's transl)].
Topics: Adrenal Cortex Hormones; Adult; Aged; Cytarabine; Drug-Related Side Effects and Adverse Reactions; Female; Glucocorticoids; Heparin; Hodgkin Disease; Humans; Kidney Failure, Chronic; Leukemia; Male; Middle Aged; Renal Dialysis | 1976 |
Letter: Intravenous cytarabine in treatment of herpes zoster in haematological malignancy.
Topics: Adolescent; Adult; Aged; Child; Cytarabine; Female; Herpes Zoster; Humans; Leukemia; Lymphoma; Male; Middle Aged | 1976 |
Close reproduction by different laboratories of characteristics of circadian rhythm in 1-beta-D-arabinofuranosylcytosine tolerance by mice.
Topics: Animals; Circadian Rhythm; Cytarabine; Drug Administration Schedule; Leukemia; Mice; Mice, Inbred Strains | 1976 |
Inhibition of RNA polymerase as a possible anti-leukaemic action of cytosine arabinoside.
Topics: Arabinofuranosyluracil; Cell-Free System; Cells, Cultured; Cytarabine; DNA-Directed RNA Polymerases; Kinetics; Leukemia; Structure-Activity Relationship | 1976 |
Leukemic reticuloendotheliosis: report of a case with prolonged remission following intensive chemotherapy.
Topics: Adult; Anemia, Aplastic; Cyclophosphamide; Cytarabine; Female; Humans; Leukemia; Leukopenia; Lymphatic Diseases; Remission, Spontaneous; Splenomegaly; Thrombocytopenia | 1976 |
Feasibility of using quinine, a potential multidrug resistance-reversing agent, in combination with mitoxantrone and cytarabine for the treatment of acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytarabine; Drug Resistance; Feasibility Studies; Female; Humans; Leukemia; Male; Membrane Glycoproteins; Middle Aged; Mitoxantrone; Neoplasm Proteins; Quinine; Treatment Outcome | 1992 |
[Treatment of leukemia: discussion].
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Granulocyte Colony-Stimulating Factor; Hematologic Tests; Humans; L-Lactate Dehydrogenase; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mercaptopurine; Prednisolone; Remission Induction | 1992 |
Recombinant human granulocyte colony-stimulating factor enhanced cytotoxicity of Ara-C in Ara-C-resistant leukemic cells from a patient with biphenotypic leukemia in cell kinetic quiescence.
Topics: Cell Cycle; Cell Division; Child; Cytarabine; DNA; Dose-Response Relationship, Drug; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Female; Granulocyte Colony-Stimulating Factor; Humans; In Vitro Techniques; Leukemia; Phenotype; Recombinant Proteins; Tritium; Tumor Cells, Cultured | 1992 |
Collection of peripheral blood stem cells mobilized by high-dose Ara-C plus VP-16 or aclarubicin followed by recombinant human granulocyte-colony stimulating factor.
Topics: Aclarubicin; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Cells; Blood Component Removal; Blood Transfusion, Autologous; Cytarabine; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Hematopoiesis; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Leukemia; Lymphoma; Male; Middle Aged; Recombinant Proteins | 1992 |
Neuropsychologic impairment in adult bone marrow transplant candidates.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Attention; Bone Marrow Transplantation; Central Nervous System Neoplasms; Chemotherapy, Adjuvant; Cognition Disorders; Cranial Irradiation; Cytarabine; Female; Humans; Leukemia; Lymphoma; Male; Memory; Methotrexate; Middle Aged; Neuropsychology; Psychomotor Performance; Regression Analysis; Whole-Body Irradiation | 1992 |
A case of congenital leukemia with monosomy 7.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 7; Cytarabine; Doxorubicin; Humans; Infant, Newborn; Karyotyping; Leukemia; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Megakaryoblastic, Acute; Male; Mercaptopurine; Monosomy; Prednisolone; Remission Induction | 1992 |
Non-aggressive therapy for chronic myeloid leukaemia in blastic transformation.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Child; Cytarabine; Daunorubicin; Doxorubicin; Female; Humans; Hydroxyurea; Leukemia; Leukemia, Myeloid, Chronic-Phase; Male; Methotrexate; Middle Aged; Remission Induction; Thioguanine; Vincristine | 1992 |
[Mitoxantrone and conventional-dose cytosine arabinoside for relapsed and refractory acute leukemia].
Topics: Acute Disease; Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Female; Humans; Leukemia; Male; Middle Aged; Mitoxantrone; Remission Induction | 1992 |
Leukemia following cisplatin-based chemotherapy for ovarian carcinoma at Roswell Park.
Topics: Adult; Carcinoma, Papillary; Cisplatin; Cyclophosphamide; Cytarabine; Doxorubicin; Female; Humans; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Middle Aged; Neoplasms, Second Primary; Ovarian Neoplasms; Thrombocytopenia | 1992 |
Intracellular cytosine arabinoside accumulation and cytosine arabinoside triphosphate formation in leukemic blast cells is inhibited by etoposide and teniposide.
Topics: Acute Disease; Adult; Aged; Amsacrine; Arabinofuranosylcytosine Triphosphate; Cytarabine; Drug Interactions; Etoposide; Humans; Leukemia; Middle Aged; Neoplastic Stem Cells; Phosphorylation; Teniposide; Tumor Cells, Cultured | 1992 |
[Clinical study of leukemia].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Humans; Leukemia; Mercaptopurine; Prednisolone | 1992 |
[Clinical application of enzyme inhibitors--hematologic malignancies].
Topics: Cytarabine; Deoxycytidine; DNA Topoisomerases, Type I; Etoposide; Gemcitabine; Humans; Leukemia; Mercaptopurine; Methotrexate; Purines; Pyrimidines; Thioguanine; Topoisomerase I Inhibitors | 1991 |
[p170 in multiple myeloma and acute leukemia].
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biomarkers, Tumor; Colonic Neoplasms; Cytarabine; Daunorubicin; Drug Resistance; Female; Gene Expression Regulation, Neoplastic; Humans; Leukemia; Male; Melphalan; Membrane Glycoproteins; Middle Aged; Multiple Myeloma; Neoplasm Proteins; Neoplastic Stem Cells; Peptichemio; Plasma Cells; Prednisone; Remission Induction; Survival Rate; Tumor Cells, Cultured; Vincristine | 1991 |
Depletion of bone marrow T-lymphocytes with an anti-CD5 monoclonal immunotoxin (ST-1 immunotoxin): effective prophylaxis for graft-versus-host disease.
Topics: Adolescent; Adult; Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation; Bone Marrow; Bone Marrow Cells; Bone Marrow Transplantation; CD5 Antigens; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Drug Evaluation; Graft vs Host Disease; Humans; Immunotoxins; Leukemia; Middle Aged; Myelodysplastic Syndromes; Ricin; Risk Factors; T-Lymphocytes; Whole-Body Irradiation | 1990 |
Myelodysplastic syndromes: analysis of 51 cases. Therapy with low doses of arabinosyl cytosine of leukaemic transformation.
Topics: Aged; Cytarabine; Cytogenetics; Humans; Leukemia; Middle Aged; Myelodysplastic Syndromes; Prognosis; Survival Analysis | 1990 |
[Kinetics of circulating hematopoietic stem cells following chemotherapy in patients with hematopoietic malignancies].
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cell Cycle; Colony-Stimulating Factors; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cells; Humans; Leukemia; Lymphoma, Non-Hodgkin; Male; Mercaptopurine; Middle Aged; Multiple Myeloma; Prednisolone; Prednisone; Vincristine | 1990 |
Comparison of antineoplastic activity of cytosine arabinoside and 5-aza-2'-deoxycytidine against human leukemic cells of different phenotype.
Topics: Antineoplastic Agents; Azacitidine; Cytarabine; Decitabine; DNA; Humans; Leukemia; Methylation; Phenotype; Tumor Cells, Cultured | 1990 |
Effects of rGM-CSF on leukemia cell proliferation and on the incorporation of cytosine arabinoside into DNA.
Topics: Bone Marrow; Cell Division; Cytarabine; DNA, Neoplasm; Gene Expression Regulation, Leukemic; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; In Vitro Techniques; Leukemia; Neoplastic Stem Cells; Proto-Oncogenes; Recombinant Proteins | 1991 |
Remission of hypoplastic acute leukemia by low dose Ara-C: one case report.
Topics: Acute Disease; Aged; Cytarabine; Female; Humans; Leukemia; Remission Induction | 1991 |
[Subleukemic acute monophagocytic leukemia. A biological phenotype close to malignant histiocytosis].
Topics: Aged; Aged, 80 and over; Aneuploidy; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Doxorubicin; Etoposide; Female; Giant Cells; Histiocytic Sarcoma; Humans; Leukemia; Leukemia, Myeloid; Phagocytosis; Thioguanine | 1991 |
Pharmacologic approaches to the treatment of meningeal malignancy.
Topics: Adolescent; Adult; Antineoplastic Agents; Aziridines; Benzoquinones; Blood-Brain Barrier; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Humans; Infant; Infant, Newborn; Leukemia; Meningeal Neoplasms; Mercaptopurine; Methotrexate; Thiotepa | 1991 |
Amsacrine is safe and effective therapy for patients with myocardial dysfunction and acute leukemia.
Topics: Amsacrine; Cardiac Output, Low; Cytarabine; Drug Therapy, Combination; Humans; Leukemia; Leukemia, Myeloid, Acute; Myocardium; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Stroke Volume | 1991 |
High-dose ara-C and etoposide in refractory or relapsing acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Evaluation; Etoposide; Female; Humans; Leukemia; Male; Middle Aged; Recurrence; Time Factors | 1991 |
[In vitro effect of combined use of BH-AC and nitrosourea derivatives against adriamycin-resistant human leukemia cell line].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Doxorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Leukemia; Nimustine; Nitrosourea Compounds; Tumor Cells, Cultured | 1991 |
A critical role for uridine nucleotides in the regulation of deoxycytidine kinase and the concentration dependence of 1-beta-D-arabinofuranosylcytosine phosphorylation in human leukemia cells.
Topics: Blast Crisis; Cytarabine; Deoxycytidine Kinase; Humans; Kinetics; Leukemia; Phosphorylation; Ribonucleotides; Tumor Cells, Cultured; Uracil Nucleotides | 1991 |
Effect of tetrahydrouridine and deoxytetrahydrouridine on the interaction between 2'-deoxycytidine and 1-beta-D-arabinofuranosylcytosine in human leukemia cells.
Topics: Arabinofuranosylcytosine Triphosphate; Cell Division; Cytarabine; Cytidine Deaminase; DCMP Deaminase; Deamination; Deoxycytidine; Deoxycytosine Nucleotides; DNA, Neoplasm; Humans; Leukemia; Tetrahydrouridine; Tumor Cells, Cultured | 1991 |
Neutropenic enterocolitis following treatment with cytosine arabinoside-containing regimens for hematological malignancies: a potentiating role for amsacrine.
Topics: Adult; Cytarabine; Enterocolitis; Humans; Leukemia; Lymphoma, Non-Hodgkin; Middle Aged; Neutropenia; Retrospective Studies; Risk Factors; Sepsis | 1991 |
Increased accumulation of cytosine arabinoside in human leukemic cells and enhancement of its cell-killing activity by uridine.
Topics: Cell Survival; Cytarabine; Drug Synergism; Humans; Leukemia; Phosphorylation; Tumor Cells, Cultured; Uridine | 1990 |
Cytarabine.
Topics: Adult; Child; Cytarabine; Humans; Leukemia | 1990 |
Ophthalmological and other toxicities related to cytosine arabinoside and total body irradiation as preparative regimen for bone marrow transplantation.
Topics: Bone Marrow Transplantation; Cerebellar Diseases; Cyclosporins; Cytarabine; Diarrhea; Evaluation Studies as Topic; Female; Georgia; Humans; Leukemia; Lymphoma; Male; Methotrexate; Myelodysplastic Syndromes; Preoperative Care; Remission Induction; Retinitis; Survival Rate; Transplantation, Autologous; Transplantation, Homologous; Whole-Body Irradiation | 1990 |
Induction of c-fos gene expression by arabinofuranosylcytosine in human KG-1 leukemia cells.
Topics: Blotting, Northern; Cycloheximide; Cytarabine; Dactinomycin; DNA-Binding Proteins; Dose-Response Relationship, Drug; Gene Expression Regulation, Leukemic; Humans; In Vitro Techniques; Leukemia; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; RNA, Messenger; Transcription, Genetic | 1990 |
Recurrent spleen enlargement during cyclic granulocyte-macrophage colony-stimulating factor therapy for myelodysplastic syndrome.
Topics: Aged; Colony-Stimulating Factors; Cytarabine; Drug Therapy, Combination; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Humans; Indium Radioisotopes; Leukemia; Lymphocyte Activation; Myelodysplastic Syndromes; Splenomegaly | 1990 |
[Comparison among three preconditioning regimens for allogeneic bone marrow transplantation in hematological malignancies].
Topics: Acute Disease; Bone Marrow Transplantation; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Humans; Leukemia; Remission Induction; Retrospective Studies; Risk; Survival Rate; Whole-Body Irradiation | 1990 |
[Two cases of bi-phenotypic type hybrid acute leukemia with 8;21 translocation].
Topics: Aclarubicin; Acute Disease; Aged; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Cytarabine; Female; Humans; Leukemia; Phenotype; Translocation, Genetic | 1990 |
[A case of complete remission from acute unclassified leukemia achieved by using a prodrug of ara C, stearyl-ara-CMP (YNK01)].
Topics: Acute Disease; Administration, Oral; Antineoplastic Agents; Arabinonucleotides; Cytarabine; Cytidine Monophosphate; Drug Administration Schedule; Female; Humans; Leukemia; Middle Aged; Prodrugs; Remission Induction | 1990 |
A phase I study of intermittent continuous infusion high dose cytosine arabinoside for acute leukemia.
Topics: Adult; Blast Crisis; Cytarabine; Drug Evaluation; Female; Gastrointestinal Diseases; Humans; Infusions, Intravenous; Leukemia; Male; Middle Aged | 1990 |
[Various aspects of production of a therapeutic form of liposomal cytarabine].
Topics: Cytarabine; Drug Contamination; Drug Storage; Freeze Drying; Humans; Injections, Intravenous; Leukemia; Liposomes; Technology, Pharmaceutical; USSR | 1990 |
Fatal pulmonary failure complicating high-dose cytosine arabinoside therapy in acute leukemia.
Topics: Acute Disease; Adult; Aged; Cytarabine; Drug Administration Schedule; Female; Humans; Intestinal Mucosa; Leukemia; Lung; Male; Middle Aged; Myocardium; Respiratory Distress Syndrome; Respiratory Insufficiency | 1990 |
Magnetic resonance imaging follow-up in patients with acute leukemia during induction chemotherapy.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Daunorubicin; Humans; Leukemia; Magnetic Resonance Imaging; Middle Aged; Mitoxantrone; Remission Induction; Thioguanine | 1990 |
Chronic myelomonocytic leukemia: clinical data, morphological features, and outcome in 56 patients.
Topics: Biomarkers, Tumor; Blast Crisis; Bone Marrow; Cytarabine; Germany, West; Hemorrhage; Humans; Leukemia; Leukemia, Myelomonocytic, Chronic; Life Tables; Prednisone; Splenomegaly; Survival Rate | 1990 |
Treatment of relapsed or refractory acute leukemia: comparison of two different regimens.
Topics: Acute Disease; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Combined Modality Therapy; Cytarabine; Etoposide; Humans; Leukemia; Mitoxantrone; Neoplasm Recurrence, Local | 1990 |
Modulatory activity of 2',2'-difluorodeoxycytidine on the phosphorylation and cytotoxicity of arabinosyl nucleosides.
Topics: Arabinonucleosides; Arabinonucleotides; Cytarabine; Deoxycytidine; Gemcitabine; Humans; Leukemia; Phosphorylation; Tumor Cells, Cultured; Vidarabine | 1990 |
Respiratory failure elicited by streptococcal septicaemia in patients treated with cytosine arabinoside.
Topics: Cytarabine; Humans; Leukemia; Respiratory Insufficiency; Sepsis; Streptococcal Infections | 1990 |
Saturation of intracellular cytosine arabinoside triphosphate accumulation in human leukemic blast cells.
Topics: Acute Disease; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Binding Sites; Biological Transport; Cell Membrane; Cytarabine; Deoxycytidine Kinase; Extracellular Space; Humans; Leukemia; Lymphocytes; Nucleosides; Phosphorylation; Thioinosine; Tumor Cells, Cultured | 1990 |
Metabolic basis of arabinonucleoside selectivity for human leukemic T- and B-lymphoblasts.
Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleosides; B-Lymphocytes; Cell Line; Cell Survival; Cytarabine; Deoxyguanosine; Humans; Leukemia; Phosphorylation; T-Lymphocytes; Vidarabine; Vidarabine Phosphate | 1985 |
High-dose cytosine arabinoside-associated pancreatitis.
Topics: Adult; Amylases; Cytarabine; Female; Humans; Isoenzymes; Leukemia; Lipase; Lymphoma; Nausea; Pain; Pancreatitis; Retrospective Studies | 1985 |
Fractional administration of adriblastin and modified route of ara-C administration for the treatment of acute leukaemia.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Doxorubicin; Humans; Leukemia; Middle Aged | 1985 |
3-Deazauridine (NSC 126849): an interesting modulator of biochemical response.
Topics: 3-Deazauridine; Acute Disease; Animals; Antineoplastic Agents; Azacitidine; Cytarabine; Decitabine; Drug Evaluation; Drug Synergism; Galactosamine; Humans; Kinetics; Leukemia; Neoplasms; Thymidine; Uridine | 1986 |
Determination of the antileukemia agents cytarabine and azacitidine and their respective degradation products by high-performance liquid chromatography.
Topics: Azacitidine; Biotransformation; Chromatography, High Pressure Liquid; Cytarabine; Drug Stability; Humans; Indicators and Reagents; Kinetics; Leukemia; Powders; Spectrophotometry, Ultraviolet | 1986 |
Influence of small doses cytosine arabinoside (Ara-C) on leukemic cells in vitro and in vivo. Results in patients with leukemia and myelodysplastic syndrome.
Topics: Adult; Aged; Blast Crisis; Bone Marrow Cells; Cell Differentiation; Cells, Cultured; Cytarabine; Dose-Response Relationship, Drug; Female; Histocytochemistry; Humans; Leukemia; Male; Middle Aged; Myelodysplastic Syndromes | 1986 |
Differential modulation of 1-beta-D-arabinofuranosylcytosine metabolism by hydroxyurea in human leukemic cell lines.
Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; B-Lymphocytes; Cell Line; Cytarabine; Deoxyadenine Nucleotides; Deoxyadenosines; Deoxycytidine; Deoxycytosine Nucleotides; Humans; Hydroxyurea; Leukemia; T-Lymphocytes; Thymine Nucleotides; Vidarabine Phosphate | 1988 |
Interaction of arabinosyl nucleotides in K562 human leukemia cells.
Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleosides; Arabinonucleotides; Cytarabine; Deoxyribonucleotides; Drug Interactions; Guanosine Triphosphate; Humans; Leukemia; Phosphorylation; Phosphotransferases; Tumor Cells, Cultured; Vidarabine; Vidarabine Phosphate | 1989 |
Leukaemia Research Fund international research symposium on cytotoxic drug resistance in leukemia and other malignancies.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Biological Transport; Cisplatin; Congresses as Topic; Cytarabine; DNA; Drug Resistance; Gene Amplification; Glutathione Transferase; Humans; Leukemia; Leukemia, Myeloid, Acute; Neoplasms; Nucleosides; Oxygen; Phenotype; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1989 |
Idarubicin in combination with intermediate-dose cytarabine in the treatment of refractory or relapsed acute leukemias.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Idarubicin; Leukemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1989 |
[Study on pathophysiology of the myelodysplastic syndromes (MDS)--pattern of dysmegakaryopoiesis related to leukemic transformation].
Topics: Aged; Cytarabine; Female; Hematopoiesis; Humans; Leukemia; Male; Megakaryocytes; Middle Aged; Myelodysplastic Syndromes | 1989 |
[Treatment of acute leukemia with "MB-triple V" therapy--a comparative study of "MB-triple V" therapy and B-triple V therapy].
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Evaluation; Etoposide; Female; Humans; Leukemia; Leukocyte Count; Male; Middle Aged; Mitoxantrone; Remission Induction; Vinblastine; Vincristine; Vindesine | 1989 |
Central nervous system involvement in haematological malignancies.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Therapy; Cytarabine; Humans; Injections, Spinal; Leukemia; Lymphoma; Meningeal Neoplasms; Methotrexate; Remission Induction; Spinal Neoplasms | 1989 |
Ara-CTP metabolism following hydroxyurea or methotrexate treatment in human leukemia cell lines.
Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cytarabine; Deoxycytidine; Deoxycytosine Nucleotides; Drug Synergism; Humans; Hydroxyurea; Leukemia; Leukemia, Promyelocytic, Acute; Methotrexate; Thymine Nucleotides; Tumor Cells, Cultured | 1989 |
[Relationship between Ara-C sensitivity of leukemic-colony forming units (L-CFU) and [3H] deoxycytidine suicide test of L-CFU].
Topics: Adult; Aged; Cell Survival; Cytarabine; Deoxycytidine; Female; Humans; Leukemia; Male; Middle Aged; Neoplastic Stem Cells; Thymidine; Tritium; Tumor Stem Cell Assay | 1989 |
High-performance liquid chromatographic assay for cytosine arabinoside and uracil arabinoside in cerebrospinal fluid and plasma.
Topics: Arabinofuranosyluracil; Chromatography, High Pressure Liquid; Cytarabine; Humans; Leukemia; Spectrophotometry, Ultraviolet; Uridine | 1989 |
[High doses of ARA C in the treatment of acute leukemia].
Topics: Acute Disease; Adolescent; Adult; Child, Preschool; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged | 1989 |
Effect of cell growth and cell differentiation on 1-beta-D-arabinofuranosylcytosine metabolism in myeloid cells.
Topics: Cell Cycle; Cell Differentiation; Cell Line; Cytarabine; Cytidine Deaminase; DCMP Deaminase; Deoxycytidine Kinase; Humans; Leukemia; Tumor Cells, Cultured | 1989 |
Central nervous system (CNS) leukemia: the role of high dose cytarabine (HDAra-C).
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Combined Modality Therapy; Cytarabine; Female; Humans; Leukemia; Lymphoma, Non-Hodgkin; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Remission Induction | 1989 |
Respiratory insufficiency in acute leukemia following treatment with cytosine arabinoside and septicemia with streptococcus viridans.
Topics: Acute Disease; Adult; Cytarabine; Female; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Respiratory Insufficiency; Sepsis; Streptococcal Infections | 1989 |
Experience with combinations containing mitoxantrone in the treatment of adult acute leukemias.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged; Mitoxantrone; Vincristine | 1989 |
A study of the mechanisms of cytotoxicity of Ara-C on three human leukemic cell lines.
Topics: Arabinofuranosylcytosine Triphosphate; Cytarabine; Deoxycytidine Kinase; Deoxycytosine Nucleotides; DNA; DNA Ligases; DNA Polymerase II; DNA, Neoplasm; Humans; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Promyelocytic, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1989 |
[High-dose cytosine arabinoside treatment of leukemia with special reference to the optimal number of doses].
Topics: Adolescent; Adult; Aged; Agranulocytosis; Bone Marrow; Cytarabine; Depression, Chemical; Drug Administration Schedule; Drug Evaluation; Female; Humans; Leukemia; Male; Middle Aged; Remission Induction | 1989 |
Combined medical and psychological treatment of postchemotherapy nausea and vomiting: a case study.
Topics: Acute Disease; Behavior Therapy; Combined Modality Therapy; Cytarabine; Diazepam; Flurazepam; Humans; Leukemia; Male; Middle Aged; Nausea; Vomiting | 1989 |
Clinical pharmacology of N4-palmitoyl-1-beta-D-arabinofuranosylcytosine in patients with hematologic malignancies.
Topics: Adult; Aged; Antineoplastic Agents; Arabinofuranosyluracil; Cytarabine; Female; Hematologic Diseases; Humans; Leukemia; Male; Middle Aged; Polycythemia Vera | 1989 |
[Effects of low dose Ara-C regimen in acute leukemias and RAEB].
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Anemia, Refractory, with Excess of Blasts; Cytarabine; Drug Evaluation; Female; Humans; Leukemia; Male; Middle Aged; Remission Induction | 1989 |
Determination of 3H-labelled cytosine arabinoside and eight metabolites in cell extracts by high-performance liquid chromatography and scintillation spectrometry.
Topics: Arabinofuranosyluracil; Cell Line; Chromatography, High Pressure Liquid; Cytarabine; Humans; Hydrogen-Ion Concentration; Leukemia; Scintillation Counting; Spectrophotometry, Ultraviolet; Tumor Cells, Cultured | 1989 |
Study of differentiation of fresh human leukemic cells by low dose cytosine arabinoside (LD Ara-C) and 12-O-tetradecanoylphorbol-13-acetate (TPA).
Topics: Antigens, Neoplasm; Blast Crisis; Bone Marrow; Cell Adhesion Molecules; Cell Differentiation; Cytarabine; Glycoproteins; Humans; Leukemia; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Inappropriate increase in erythropoietin titers during chemotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Asparaginase; Cyclophosphamide; Cytarabine; Daunorubicin; Erythropoietin; Female; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Vincristine | 1989 |
Differential metabolism of 9-beta-D-arabinofuranosylguanine in human leukemic cells.
Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleosides; Arabinonucleotides; Cell Division; Cytarabine; Guanine; Humans; In Vitro Techniques; Leukemia; T-Lymphocytes; Tumor Cells, Cultured | 1989 |
Low-dose cytosine arabinoside-induced remission of lymphoblastic leukemia in a cat.
Topics: Animals; Cat Diseases; Cats; Cytarabine; Leukemia; Leukemia Virus, Feline; Leukemia, Lymphoid; Remission Induction | 1987 |
Effect of 1-beta-D-arabinofuranosylcytosine (ara-C) on nuclear topoisomerase II activity and on the DNA cleavage and cytotoxicity produced by 4'-(9-acridinylamino)methanesulfon-m-anisidide (m-AMSA) and etoposide in m-AMSA-sensitive and -resistant human le
Topics: Amsacrine; Cell Division; Cell Nucleus; Cytarabine; DNA; DNA Topoisomerases, Type II; Drug Resistance; Etoposide; Humans; Leukemia; Tumor Cells, Cultured | 1987 |
[The effect of antileukemic drugs on superoxide (O2-) production by human neutrophils].
Topics: Aclarubicin; Antineoplastic Agents; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia; Naphthacenes; Neutrophils; Superoxides | 1987 |
Acute leukaemia during pregnancy.
Topics: Acute Disease; Adult; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Female; Humans; Infant, Newborn; Labor, Induced; Leukemia; Pregnancy; Pregnancy Complications, Neoplastic; Thioguanine | 1988 |
Pharmacology studies of 1-beta-D-arabinofuranosylcytosine in pediatric patients with leukemia and lymphoma after a biochemically optimal regimen of loading bolus plus continuous infusion of the drug.
Topics: Adolescent; Child; Child, Preschool; Cytarabine; Deoxycytidine Kinase; Humans; Infant; Leukemia; Lymphoma | 1989 |
4-demethoxydaunorubicin (idarubicin) in combination with 1-beta-D-arabinofuranosylcytosine in the treatment of relapsed or refractory acute leukemia.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Evaluation; Female; Humans; Idarubicin; Leukemia; Male; Middle Aged | 1989 |
In vitro evidence for dose-dependent cytotoxicity as the predominant effect of low dose Ara-C on human leukemic and normal marrow cells.
Topics: Bone Marrow; Cell Differentiation; Cell Survival; Cells, Cultured; Cytarabine; Dose-Response Relationship, Drug; Hematopoietic Stem Cells; Humans; Leukemia | 1989 |
[New combination chemotherapy of adult acute nonlymphocytic leukemia].
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Leukemia; Male; Methotrexate; Middle Aged; Prednisolone; Vincristine; Zinostatin | 1985 |
Combination therapy with aclacinomycin in acute leukemia.
Topics: Aclarubicin; Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Leukemia; Naphthacenes; Thioguanine | 1986 |
Influence of cytarabine on mitochondrial function and mitochondrial biogenesis.
Topics: Cell Line; Citrate (si)-Synthase; Cytarabine; Electron Transport Complex IV; Humans; Intracellular Membranes; Leukemia; Membrane Potentials; Mitochondria; Proteins | 1987 |
Simultaneous infusion of high-dose cytosine arabinoside with cyclophosphamide followed by total body irradiation and marrow infusion for the treatment of patients with advanced hematological malignancy.
Topics: Adolescent; Adult; Bone Marrow Transplantation; Child; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Whole-Body Irradiation | 1988 |
Low-dose cytarabine in myelodysplastic syndromes and acute leukemia. A comment.
Topics: Acute Disease; Cytarabine; Hematopoietic Stem Cells; Humans; Leukemia; Myelodysplastic Syndromes | 1986 |
Low-dose cytosine arabinoside in the treatment of relapsed and refractory acute non-lymphocytic leukaemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia | 1986 |
Formation of cytosine arabinoside-5'-triphosphate in cultured human leukemic cell lines correlates with nucleoside transport capacity.
Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Biological Transport; Cell Line; Cell Membrane; Cytarabine; Humans; Leukemia | 1987 |
Low-dose cytosine arabinoside in the treatment of acute nonlymphocytic leukemia.
Topics: Cytarabine; Humans; Leukemia | 1988 |
[Megakaryoblastic leukemia with hypodiploidy in a girl with trisomy 21].
Topics: Blood Platelets; Bone Marrow; Child, Preschool; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Down Syndrome; Female; Humans; Leukemia; Primary Myelofibrosis | 1985 |
In vitro short-term sensitivity test for the prediction of response to chemotherapy in acute non-lymphocytic leukemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cells, Cultured; Cytarabine; Daunorubicin; Drug Screening Assays, Antitumor; Female; Humans; Leukemia; Male; Middle Aged; Time Factors; Uridine | 1988 |
[Intermediate-dose cytosine arabinoside in combination with mitoxantrone in the treatment of refractory leukemia].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged; Mitoxantrone; Remission Induction | 1988 |
["A-Triple-V" treatment of relapsed or refractory acute leukemia].
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Evaluation; Etoposide; Female; Humans; Leukemia; Male; Middle Aged; Pilot Projects; Remission Induction; Vinblastine; Vincristine | 1988 |
Effects of clinical combinations of antileukemic drugs on DNA ligase from human thymocytes and normal, stimulated, or leukemic lymphocytes.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Daunorubicin; DNA Ligases; Doxorubicin; Drug Screening Assays, Antitumor; Female; Humans; Kinetics; Leukemia; Lymphocytes; Male; Middle Aged; Polynucleotide Ligases; Prednisone; T-Lymphocytes; Vincristine | 1988 |
Combined chemotherapy with m-amsacrine in high-risk patients with acute non-lymphocytic leukemia.
Topics: Acute Disease; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Follow-Up Studies; Humans; Leukemia; Middle Aged; Thioguanine | 1987 |
High-dose ara-C and VP-16 before conditioning for bone marrow transplantation in patients with high-risk leukemia.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Cytarabine; Etoposide; Female; Humans; Leukemia; Male | 1987 |
Bone marrow transplantation for acute leukemia and lymphoma with high-dose cytosine arabinoside and total body irradiation.
Topics: Adolescent; Bone Marrow Transplantation; Child; Combined Modality Therapy; Cytarabine; Humans; Leukemia; Lymphoma; Whole-Body Irradiation | 1987 |
Proto-oncogene transcript levels and acute nonlymphocytic leukemia.
Topics: Acute Disease; Blast Crisis; Bone Marrow; Cell Differentiation; Cell Division; Cytarabine; Gene Expression Regulation; Histones; Humans; Leukemia; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogenes; RNA, Neoplasm; Triose-Phosphate Isomerase | 1987 |
Prolonged survival after high-dose cytosine arabinoside and amsacrine induction in patients with previously untreated de novo acute nonlymphocytic leukemia.
Topics: Acute Disease; Amsacrine; Bone Marrow Transplantation; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia; Prognosis | 1987 |
Sequential pilot studies of intensive postremission chemotherapy for acute nonlymphocytic leukemia.
Topics: Acute Disease; Adolescent; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmustine; Combined Modality Therapy; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia; Male; Middle Aged; Mitoxantrone; Pilot Projects; Thioguanine | 1987 |
Modulation of arabinosylnucleoside metabolism by arabinosylnucleotides in human leukemia cells.
Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cytarabine; Humans; Leukemia; Phosphorylation; Tumor Cells, Cultured; Vidarabine | 1988 |
Consolidation therapy without maintenance for acute non-lymphoblastic leukaemia.
Topics: Actuarial Analysis; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Humans; Leukemia; Male; Middle Aged; Prognosis; Remission Induction; Retrospective Studies; Thioguanine; Time Factors | 1988 |
VP-16-based regimen in adult acute nonlymphoblastic leukemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Erythropoiesis; Etoposide; Hematopoietic Stem Cells; Humans; Leukemia; Thioguanine; Vincristine | 1988 |
Chemotherapy for relapsed and resistant acute nonlymphoblastic leukemia. Effect of ATA, an amsacrine-containing regime.
Topics: Acute Disease; Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Resistance; Female; Humans; Leukemia; Male; Middle Aged; Recurrence; Thioguanine | 1988 |
[Experiences with low-dos Ara-C in the therapy of hematological neoplasms].
Topics: Adult; Aged; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia; Male; Middle Aged; Myelodysplastic Syndromes | 1988 |
Non-cardiogenic pulmonary edema complicating intermediate and high-dose Ara C treatment for relapsed acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged; Pulmonary Edema; Radiography, Thoracic; Recurrence; Retrospective Studies | 1988 |
Therapeutic effects of low-dose cytosine arabinoside, alpha-interferon, 1 alpha-hydroxyvitamin D3 and retinoic acid in acute leukemia and myelodysplastic syndromes.
Topics: Actuarial Analysis; Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Female; Humans; Hydroxycholecalciferols; Interferon Type I; Leukemia; Male; Middle Aged; Myelodysplastic Syndromes; Remission Induction; Tretinoin | 1988 |
Mitoxantrone.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cytarabine; Daunorubicin; DNA; Drug Administration Schedule; Humans; Leukemia; Mitoxantrone | 1988 |
[A therapeutic trial with low-dose Ara-C in acute nonlymphocytic leukemia and myelodysplastic syndromes: a study of 15 cases].
Topics: Acute Disease; Adult; Aged; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged; Myelodysplastic Syndromes | 1988 |
Recurrent fungal pneumonias in patients with acute nonlymphocytic leukemia undergoing multiple courses of intensive chemotherapy.
Topics: Acute Disease; Adult; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Doxorubicin; Female; Humans; Leukemia; Lung Diseases, Fungal; Male; Pneumonia; Recurrence; Remission Induction; Risk Factors | 1988 |
A study on the induction of differentiation of human leukemic cells by harringtonine combined with cytarabine.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cell Differentiation; Cytarabine; Female; Harringtonines; Humans; Leukemia; Leukocyte Count; Male; Middle Aged; Pancytopenia; Tumor Stem Cell Assay | 1988 |
Cerebrospinal fluid protein findings during prophylaxis and treatment of neuromeningosis in leukaemic patients.
Topics: Adult; Aged; Albumins; Central Nervous System Diseases; Cerebrospinal Fluid Proteins; Cytarabine; Female; Humans; Immunoglobulin A; Immunoglobulin G; Injections, Spinal; Leukemia; Male; Meningeal Neoplasms; Methotrexate; Middle Aged | 1987 |
[Treatment of childhood acute non-lymphocytic leukemia with the AVC regimen (adriamycin, vincristine and cytosine arabinoside)].
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Administration Schedule; Female; Humans; Infant; Leukemia; Leukocyte Count; Male; Vincristine | 1987 |
[Effectiveness of low dose Ara-C in acute nonlymphocytic leukemia and myelodysplastic syndromes--analysis of factors influencing the duration of responses, survival and clinical effects].
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged; Myelodysplastic Syndromes; Remission Induction | 1987 |
[The effect of N4-behenoyl-1-beta-D-arabinofuranosylcytosine on human erythrocytes].
Topics: Acute Disease; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood Sedimentation; Cytarabine; Erythrocytes; Humans; Leukemia; Osmotic Fragility | 1987 |
["B-triple V" therapy as a initial induction treatment of acute leukemias].
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Humans; Leukemia; Male; Middle Aged; Remission Induction; Vinblastine; Vincristine | 1987 |
[Care of patients with leukemia complicated by diabetes mellitus during chemotherapy].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Diabetes Mellitus; Female; Harringtonines; Humans; Leukemia; Male; Prednisone; Vincristine | 1987 |
Ocular toxicity of low dose cytosar.
Topics: Acute Disease; Cytarabine; Eye; Humans; Leukemia | 1987 |
[Low-dose cytosine arabinoside therapy in relapsed acute leukemia: correlation of clinical response and in vitro sensitivity tests].
Topics: Acute Disease; Adolescent; Adult; Age Factors; Child; Cytarabine; Drug Screening Assays, Antitumor; Female; Humans; Leukemia; Male; Recurrence; Tumor Cells, Cultured | 1987 |
Aclacinomycin A and behenoyl arabinofuranosylcytosine combination chemotherapy for previously untreated acute leukemia.
Topics: Aclarubicin; Actuarial Analysis; Acute Disease; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Child; Child, Preschool; Cytarabine; Humans; Leukemia; Middle Aged; Naphthacenes | 1986 |
Neurotoxicity associated with systemic high-dose cytosine arabinoside.
Topics: Acute Disease; Adolescent; Adult; Aged; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Nervous System Diseases | 1986 |
Current and future aspects on the clinical use of Ara-C in leukemia. Proceedings from a symposium held at the 3rd European Conference on Clinical Oncology and Cancer Nursing, June 19, 1985, in Stockholm.
Topics: Cytarabine; Humans; Leukemia | 1986 |
Dose-related pharmacologic effects of high dose ara-C and its use in combination with asparaginase for the treatment of patients with acute non-lymphocytic leukemia.
Topics: Acute Disease; Animals; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Carcinoma, Ehrlich Tumor; Cell Line; Cytarabine; Dose-Response Relationship, Drug; Drug Resistance; Humans; Leukemia; Leukemia L5178; Mice | 1986 |
Cellular pharmacology and optimal therapeutic concentrations of 1-beta-D-arabinofuranosylcytosine 5'-triphosphate in leukemic blasts during treatment of refractory leukemia with high-dose 1-beta-D-arabinofuranosylcytosine.
Topics: Acute Disease; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Biotransformation; Chromatography, High Pressure Liquid; Cytarabine; Humans; Kinetics; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute | 1986 |
[Effect of low-dose Ara-C in the treatment of refractory, atypical leukemia and myelodysplastic syndrome].
Topics: Adolescent; Adult; Aged; Child; Cytarabine; Drug Administration Schedule; Drug Evaluation; Female; Humans; Infusions, Parenteral; Injections, Subcutaneous; Leukemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes | 1986 |
A phase I-II study of cytosine arabinoside, daunorubicin, and VP16-213 in adult patients with acute non-lymphocytic leukemia.
Topics: Acute Disease; Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Evaluation; Etoposide; Female; Humans; Leukemia; Male; Middle Aged; Nausea; Stomatitis; Vomiting | 1986 |
Prediction of response of patients with acute nonlymphocytic leukaemia to remission induction therapy: use of clinical measurements.
Topics: Acute Disease; Age Factors; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Humans; Leukemia; Middle Aged; Naphthacenes; Prognosis; Retrospective Studies; Time Factors | 1986 |
[Mucosal injury of aclacinomycin A in patients with adult acute leukemia--comparison of BH-AC. AMP therapy and BH-AC. DMP therapy].
Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Hemorrhage; Humans; Leukemia; Male; Mercaptopurine; Middle Aged; Mucous Membrane; Naphthacenes; Prednisolone; Urinary Bladder Diseases | 1986 |
Pharmacology and toxicity of high-dose cytarabine by 72-hour continuous infusion.
Topics: Acute Disease; Cytarabine; Dose-Response Relationship, Drug; Drug Evaluation; Humans; Infusions, Parenteral; Kinetics; Leukemia; Leukemia, Lymphoid | 1986 |
Oral idarubicin in combination with cytosine-arabinoside in previously untreated patients with acute non-lymphocytic leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Daunorubicin; Female; Humans; Idarubicin; Leukemia; Male; Middle Aged | 1986 |
Treatment of acute leukaemia with m-AMSA in combination with cytosine arabinoside.
Topics: Aged; Amsacrine; Chemical and Drug Induced Liver Injury; Cytarabine; Female; Gastrointestinal Diseases; Heart Diseases; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Neutropenia; Thrombocytopenia | 1986 |
Surgery for the acute abdomen in adults with leukaemia.
Topics: Abdomen, Acute; Adolescent; Adult; Appendectomy; Colectomy; Cytarabine; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Retrospective Studies | 1986 |
In-vitro studies on phosphorylation and dephosphorylation of cytosine arabinoside in human leukemic cells.
Topics: Bone Marrow; Cytarabine; Humans; In Vitro Techniques; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Phosphorylation | 1987 |
Saturation of 1-beta-D-arabinofuranosylcytosine 5'-triphosphate accumulation in leukemia cells during high-dose 1-beta-D-arabinofuranosylcytosine therapy.
Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Blast Crisis; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Infusions, Intravenous; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Metabolic Clearance Rate | 1987 |
A phase II study of high-dose cytosine arabinoside in the treatment of acute leukaemia in adults.
Topics: Acute Disease; Adult; Aged; Blast Crisis; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Middle Aged; Time Factors | 1987 |
Daunorubicin versus aclarubicin in combination with cytarabine and thioguanine in elderly patients with acute nonlymphocytic leukemia, a preliminary report.
Topics: Aclarubicin; Acute Disease; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia; Male; Middle Aged; Naphthacenes; Thioguanine | 1987 |
Idarubicin in sequential combination with cytosine arabinoside in the treatment of relapsed and refractory patients with acute non-lymphoblastic leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Idarubicin; Leukemia; Male; Middle Aged | 1987 |
Comparison between the plasma and intracellular pharmacology of 1-beta-D-arabinofuranosylcytosine and 9-beta-D-arabinofuranosyl-2-fluoroadenine 5'-monophosphate in patients with relapsed leukemia.
Topics: Adult; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cytarabine; DNA Replication; Drug Evaluation; Female; Half-Life; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Vidarabine | 1987 |
Biochemical pharmacology of high dose 1-beta-D-arabinofuranosylcytosine in childhood acute leukemia.
Topics: Arabinofuranosylcytosine Triphosphate; Child; Cytarabine; Half-Life; Humans; Leukemia; Leukemia, Lymphoid; Neutropenia | 1987 |
Idarubicin in combination with etoposide and cytarabine in adult untreated acute non lymphoblastic leukemia.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Idarubicin; Leukemia; Male; Middle Aged | 1987 |
Regulation of 1-beta-D-arabinofuranosylcytosine 5'-triphosphate accumulation in human leukemia cells by deoxycytidine 5'-triphosphate.
Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cell Cycle; Cell Line; Cytarabine; Deoxycytosine Nucleotides; Humans; Interphase; Leukemia; Nucleotides; Phosphorylation; T-Lymphocytes | 1986 |
Effects of 1-beta-D-arabinofuranosylcytosine on proto-oncogene expression in human U-937 cells.
Topics: Actins; Cell Division; Cell Line; Cytarabine; Humans; Leukemia; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogenes; Transcription, Genetic; Tretinoin | 1986 |
Cerebrospinal fluid beta-2-microglobulin: a reliable index of leukaemic infiltration of central nervous system.
Topics: Acute Disease; Adolescent; Adult; Aged; beta 2-Microglobulin; Central Nervous System Diseases; Child; Cytarabine; Female; Follow-Up Studies; Humans; Injections, Spinal; Leukemia; Male; Methotrexate; Middle Aged | 1986 |
Fatal cardiac toxicity in bone marrow transplant patients receiving cytosine arabinoside, cyclophosphamide, and total body irradiation.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cyclophosphamide; Cytarabine; Female; Heart Diseases; Humans; Leukemia; Myocardium; Pericardium; Whole-Body Irradiation | 1987 |
Separation of 1-beta-D-arabinofuranosylcytosine 5'-triphosphate and 9-beta-D-arabinofuranosyl-2-fluoroadenine 5'-triphosphate in human leukemia cells by high-performance liquid chromatography.
Topics: Cells, Cultured; Chromatography, High Pressure Liquid; Cytarabine; Humans; Kinetics; Leukemia; Nucleotides; Vidarabine | 1987 |
[Intensive polychemotherapy in the treatment of acute non-lymphoblastic leukemia: comparison of the prospective protocols DATOP/79 and DATOP/82].
Topics: Actuarial Analysis; Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia; Male; Middle Aged; Prednisone; Thioguanine; Vincristine | 1987 |
[In vitro test for studying sensitivity to Ara-C in leukemic patients].
Topics: Adolescent; Adult; Child; Colony-Forming Units Assay; Cytarabine; DNA, Neoplasm; Humans; Leukemia; Middle Aged; Tumor Stem Cell Assay | 1987 |
[The clinical effect of low-dose Ara-C in patients with refractory acute nonlymphocytic leukemia and myelodysplastic syndrome].
Topics: Acute Disease; Adult; Aged; Chromatography, High Pressure Liquid; Cytarabine; Female; Humans; Infusions, Intravenous; Injections, Subcutaneous; Leukemia; Male; Middle Aged; Myelodysplastic Syndromes | 1987 |
In vitro exposure of leukemic cells to low concentration Arabinosyl Cytosine: no evidence of differentiation inducing activity.
Topics: Acute Disease; Adult; Aged; Bone Marrow; Bone Marrow Cells; Cell Differentiation; Cell Transformation, Neoplastic; Cells, Cultured; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia; Middle Aged; Myelodysplastic Syndromes | 1987 |
In vitro correlates of low dose ara-C efficacy: clinical, cytogenetic, and bone marrow culture analysis.
Topics: Acute Disease; Adult; Aged; Bone Marrow Cells; Cells, Cultured; Cytarabine; Cytogenetics; Dose-Response Relationship, Drug; Female; Humans; Leukemia; Male; Middle Aged | 1987 |
[Neuromeningeal localizations in acute leukemia and non-Hodgkin's lymphoma. Protocol combining BCNU-cytosine arabinoside].
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cytarabine; Leukemia; Lymphoma, Non-Hodgkin; Meningeal Neoplasms | 1987 |
Evaluation of intensive postremission chemotherapy for adults with acute nonlymphocytic leukemia using high-dose cytosine arabinoside with L-asparaginase and amsacrine with etoposide.
Topics: Acute Disease; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cytarabine; Drug Evaluation; Etoposide; Humans; Leukemia; Middle Aged; Remission Induction; Statistics as Topic | 1987 |
Cerebellar toxicity with high-dose cytosine arabinoside.
Topics: Adolescent; Adult; Age Factors; Aged; Cerebellar Diseases; Child; Child, Preschool; Cytarabine; Female; Humans; Infant; Leukemia; Lymphoma; Male; Middle Aged | 1987 |
CYTOSAR-U sterile powder: therapeutic biological effects. Proceedings of a symposium. November 30-December 2, 1986, Kalamazoo, MI.
Topics: Acute Disease; Animals; Cytarabine; Humans; Leukemia; Lymphoma | 1987 |
Low-dose ara-C in acute nonlymphocytic leukemia and myelodysplastic syndromes: a review of 20 years' experience.
Topics: Acute Disease; Cytarabine; Humans; Leukemia; Myelodysplastic Syndromes; Prognosis | 1987 |
High-dose cytosine arabinoside and daunorubicin as consolidation therapy for acute nonlymphocytic leukemia in first remission: an update.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Humans; Leukemia; Middle Aged; Prognosis | 1987 |
Pharmacokinetic parameters of 1-beta-D-arabinofuranosylcytosine (ara-C) and their relationship to intracellular metabolism of ara-C, toxicity, and response of patients with acute nonlymphocytic leukemia treated with conventional and high-dose ara-C.
Topics: Acute Disease; Animals; Arabinofuranosylcytosine Triphosphate; Arabinofuranosyluracil; Cytarabine; Drug Administration Schedule; Humans; Leukemia; Leukemia L1210; Metabolic Clearance Rate; Mice; Uridine Kinase | 1987 |
Saturation of ara-CTP accumulation during high-dose ara-C therapy: pharmacologic rationale for intermediate-dose ara-C.
Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Infusions, Intravenous; Leukemia; Metabolic Clearance Rate | 1987 |
High-dose cytosine arabinoside and mitoxantrone in high-risk acute nonlymphoblastic leukemia.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Leukemia; Male; Middle Aged; Mitoxantrone | 1987 |
ara-C in plasma and ara-CTP in leukemic cells after subcutaneous injection and continuous intravenous infusion of ara-C in patients with acute nonlymphoblastic leukemia.
Topics: Acute Disease; Adult; Aged; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cytarabine; Female; Humans; Infusions, Intravenous; Injections, Subcutaneous; Leukemia; Male; Metabolic Clearance Rate; Middle Aged | 1987 |
Central nervous system effects of high-dose cytosine arabinoside.
Topics: Adult; Age Factors; Aged; Cerebellar Diseases; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Leukemia; Middle Aged | 1987 |
Studies of ara-C metabolism in acute leukemia.
Topics: Acute Disease; Arabinofuranosylcytosine Triphosphate; Bromodeoxyuridine; Cell Line; Cytarabine; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Resistance; Humans; Leukemia; Thymidine | 1987 |
Cell cycle and drug sensitivity studies of leukemic cells that appear relevant in determining response to chemotherapy in acute nonlymphocytic leukemia.
Topics: Acute Disease; Bone Marrow; Bromodeoxyuridine; Cell Cycle; Cytarabine; DNA Replication; DNA, Neoplasm; Humans; Leukemia | 1987 |
High-dose cytosine arabinoside in the consolidation therapy of acute nonlymphocytic leukemia in remission.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Female; Humans; Leukemia; Male; Methotrexate; Methylprednisolone; Middle Aged | 1987 |
Sequential high-dose ara-C and asparaginase versus high-dose ara-C alone in the treatment of patients with relapsed and refractory acute leukemias.
Topics: Acute Disease; Asparaginase; Cerebellar Diseases; Cytarabine; Diarrhea; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation; Humans; Leukemia; Neoplasm Recurrence, Local | 1987 |
Long-term relapse-free survival in childhood acute nonlymphocytic leukemia.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Diterpenes; Dose-Response Relationship, Drug; Doxorubicin; Humans; Leukemia; Retinyl Esters; Thioguanine; Vitamin A | 1987 |
[Clinical and pharmacokinetic studies of high dose N4-behenoyl-1-beta-D-arabinofuranosylcytosine].
Topics: Antineoplastic Agents; Cytarabine; Humans; Kinetics; Leukemia; Lymphoma, Non-Hodgkin | 1987 |
Toxicity of high dose Ara-C in children and adolescents.
Topics: Adolescent; Child; Child, Preschool; Cytarabine; Drug Evaluation; Female; Humans; Infant; Leukemia; Male; Remission Induction | 1987 |
Deoxycytidine preferentially protects normal versus leukemic myeloid progenitor cells from cytosine arabinoside-mediated cytotoxicity.
Topics: Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Cytarabine; Deoxycytidine; DNA; Humans; Leukemia; Neoplastic Stem Cells; Phosphates; Stem Cells | 1987 |
Pediatric Oncology Group Study of in vitro clonal growth patterns of leukemic cells in childhood acute nonlymphocytic leukemia as a predictor of induction response.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Child; Clone Cells; Cytarabine; Daunorubicin; Dexamethasone; Humans; Leukemia; Prognosis; Remission Induction; Thioguanine; Tumor Stem Cell Assay; Vincristine | 1987 |
Preliminary results of consolidation therapy with high-dose cytosine arabinoside for patients with bad-risk or relapsed acute leukemia or lymphoblastic non-Hodgkin's lymphoma.
Topics: Acute Disease; Adolescent; Adult; Cytarabine; Female; Humans; Leukemia; Lymphoma, Non-Hodgkin; Male; Middle Aged; Neoplasm Recurrence, Local; Risk | 1987 |
Small-dose cytosine arabinoside in the treatment of elderly patients with acute leukemia and refractory anemia with excess of blast.
Topics: Acute Disease; Aged; Anemia, Refractory, with Excess of Blasts; Bone Marrow Diseases; Cytarabine; Humans; Infections; Injections, Subcutaneous; Leukemia; Male; Middle Aged; Nausea | 1986 |
[A phase II study of N4-palmitoyl-1-beta-D-arabinofuranosylcytosine (PL-AC) in patients with acute leukemia and myelodysplastic syndromes. Cooperative Study Group for PL-AC].
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Cytarabine; Drug Evaluation; Female; Humans; Leukemia; Male; Middle Aged; Myelodysplastic Syndromes | 1987 |
Low-dose Ara-C in myelodysplastic syndromes and acute nonlymphoid leukemia. Experience with seven patients.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Leukemia; Male; Middle Aged; Myelodysplastic Syndromes | 1987 |
The use of amsacrine plus intermediate-dose cytosine arabinoside in relapsed and refractory acute nonlymphocytic leukemia.
Topics: Acute Disease; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Leukemia; Middle Aged; Remission Induction | 1987 |
Serum zinc and copper as prognostic factors in acute nonlymphocytic leukemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Copper; Cytarabine; Daunorubicin; Female; Humans; Leukemia; Male; Middle Aged; Prognosis; Remission Induction; Vincristine; Zinc | 1987 |
Treatment of refractory acute leukemia with high-dose cytosine arabinoside.
Topics: Acute Disease; Adolescent; Adult; Cytarabine; Female; Hepatitis B virus; Humans; Leukemia; Male; Middle Aged | 1987 |
[High-dose cytosine arabinoside and L-asparaginase in the treatment of refractory or recurrent acute non-lymphoblastic leukemia].
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged; Neoplasm Recurrence, Local; Remission Induction | 1987 |
Cell kinetic effect of low dose arabinosyl cytosine.
Topics: Acute Disease; Bone Marrow; Cell Cycle; Cytarabine; Humans; Leukemia; Time Factors | 1987 |
Variables predicting response to high dose cytosine arabinoside therapy in patients with refractory acute leukemia.
Topics: Acute Disease; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia | 1987 |
High-dose VP-16 with intermediate-dose cytosine arabinoside in the treatment of relapsed acute nonlymphocytic leukemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Evaluation; Female; Humans; Leukemia; Liver; Male; Middle Aged; Podophyllotoxin; Recurrence; Time Factors | 1987 |
Pharmacokinetic studies of intermediate-to high-dose 1-beta-D-arabinofuranosylcytosine in children with acute leukemia and lymphoma.
Topics: Acute Disease; Child; Chromatography, High Pressure Liquid; Cytarabine; Humans; Leukemia; Lymphoma, Non-Hodgkin | 1987 |
High-dose cytosine arabinoside, daunomycin and 6-thioguanine in relapsed or refractory acute nonlymphocytic leukemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Diseases; Cytarabine; Daunorubicin; Gastrointestinal Diseases; Humans; Leukemia; Recurrence; Remission Induction; Thioguanine | 1987 |
Phase I clinical and pharmacokinetic study of N4-behenoyl-1-beta-D-arabinofuranosylcytosine.
Topics: Adult; Aged; Antineoplastic Agents; Cytarabine; Dose-Response Relationship, Drug; Drug Evaluation; Drug Tolerance; Female; Hematopoiesis; Humans; Kinetics; Leukemia; Lymphoma; Male; Metabolic Clearance Rate; Middle Aged | 1986 |
Clinical effect of low dose ara-C in twenty patients with acute nonlymphocytic leukemia, atypical leukemia, and refractory anemia with excess of blasts.
Topics: Acute Disease; Adult; Aged; Anemia, Refractory; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged | 1986 |
Effect of cytosine arabinoside on leukemic blast cell colonies.
Topics: Acute Disease; Adolescent; Adult; Aged; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged; Neoplastic Stem Cells | 1986 |
[Treatment of atypical leukemia].
Topics: Aged; Cytarabine; Drug Administration Schedule; Humans; Leukemia; Male | 1986 |
[High-dose Ara-C treatment of acute leukemia].
Topics: Acute Disease; Antineoplastic Agents; Cytarabine; Drug Resistance; Humans; Leukemia | 1986 |
Metabolism of ara-C by blast cells from patients with ANLL.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Cytarabine; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Resistance; Female; Humans; Leukemia; Male; Middle Aged | 1986 |
Treatment of leukemia and myelodysplastic syndromes with orally administered N4-palmitoyl-1-beta-D-arabinofuranosylcytosine.
Topics: Administration, Oral; Adolescent; Adult; Aged; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged; Myelodysplastic Syndromes; Myeloproliferative Disorders | 1986 |
Comprehensive protective care in the management of acute leukemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cross Infection; Cytarabine; Daunorubicin; Humans; Leukemia; Middle Aged; Patient Care Planning; Prednisone; Thioguanine; Vincristine | 1986 |
[A new drug and current strategy in the treatment of acute non-lymphocytic leukemia in adults].
Topics: Acute Disease; Adult; Aminoacridines; Amsacrine; Anthraquinones; Antineoplastic Agents; Cytarabine; Drug Administration Schedule; Etoposide; Humans; Leukemia; Mitoxantrone | 1986 |
Drug sensitivity and cross-resistance of the 4'-(9-acridinylamino)methanesulfon-m-anisidide-resistant subline of HL-60 human leukemia.
Topics: Aminoacridines; Amsacrine; Cell Line; Cell Survival; Cytarabine; Doxorubicin; Drug Resistance; Etoposide; Humans; Leukemia | 1986 |
Toxicity of sequential high-dose ARA-C asparaginase treatment in childhood poor risk leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Cytarabine; Drug Evaluation; Female; Humans; Leukemia; Male | 1986 |
[Myelodysplastic syndromes].
Topics: Chromosome Aberrations; Cytarabine; Humans; Leukemia; Myelodysplastic Syndromes; Prognosis | 1986 |
Effect of m-AMSA on the cellular pharmacology of ara-CTP in human leukemic cells during therapy with high-dose ara-C.
Topics: Amsacrine; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia; Metabolic Clearance Rate | 1986 |
Low-dose Ara-C can cause complete remission of acute non-lymphocytic leukemia: differentiation induction?
Topics: Acute Disease; Adolescent; Adult; Bone Marrow; Cell Differentiation; Child, Preschool; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged; Remission Induction | 1986 |
Low dose ara-C administered by continuous subcutaneous infusion: a pharmacologic evaluation.
Topics: Adult; Aged; Cytarabine; Humans; Leukemia; Male; Middle Aged; Preleukemia | 1986 |
Ara-C syndrome during low-dose continuous infusion therapy.
Topics: Aged; Cytarabine; Female; Fever; Humans; Infusions, Intravenous; Leukemia; Male; Middle Aged; Pericarditis; Peritonitis; Skin Diseases; Syndrome | 1986 |
[Strategy of chemotherapy of a patient with acute leukemia based on the mechanism of action of drugs].
Topics: Acute Disease; Cytarabine; Erythrocytes; Humans; Kinetics; Leukemia; Mercaptopurine | 1986 |
[Prognostic factors related to remission duration and the effects of maintenance therapy in BHAC-DMP therapy in adult acute non-lymphocytic leukemia patients].
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Deoxycytidine Monophosphate; Humans; Leukemia; Middle Aged; Prognosis; Regression Analysis; Remission Induction | 1986 |
[Intermediate- and high-dose cytosine arabinoside therapy in acute refractory leukemia].
Topics: Acute Disease; Adult; Cytarabine; Drug Administration Schedule; Drug Resistance; Female; Humans; Leukemia; Male; Middle Aged | 1987 |
Prolonged unmaintained remission after intensive consolidation therapy in adult acute nonlymphocytic leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Humans; Leukemia; Middle Aged; Mycoses; Pilot Projects | 1987 |
Etoposide in combination with cytarabine, doxorubicin, and 6-thioguanine for treatment of acute nonlymphoblastic leukemia in a protocol adjusted for age.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Bone Marrow; Cytarabine; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Leukemia; Male; Middle Aged; Thioguanine | 1987 |
Limited efficacy of a four-day course of high-dose cytosine arabinoside in the treatment of poor-risk patients with acute nonlymphocytic leukemia.
Topics: Acute Disease; Adult; Age Factors; Aged; Aged, 80 and over; Cytarabine; Humans; Leukemia; Middle Aged; Pilot Projects; Prognosis; Risk; Time Factors | 1986 |
Membrane transport influences the rate of accumulation of cytosine arabinoside in human leukemia cells.
Topics: Acute Disease; Adult; Animals; Biological Transport; Carcinoma, Ehrlich Tumor; Cell Line; Cell Membrane; Cytarabine; Humans; Kinetics; Leukemia; Leukemia L5178; Leukemia P388; Mathematics; Mice | 1987 |
High-dose cytosine arabinoside as the initial treatment of poor-risk patients with acute nonlymphocytic leukemia: a Leukemia Intergroup Study.
Topics: Acute Disease; Aged; Blood Cell Count; Bone Marrow; Cytarabine; Hematopoiesis; Humans; Leukemia; Prognosis; Statistics as Topic; Time Factors | 1987 |
[Cytosine arabinoside as a polyvalent drug in the treatment of acute non-lymphoid leukemias].
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Biological Availability; Cell Differentiation; Cytarabine; DNA Replication; Humans; Infusions, Intravenous; Injections, Intravenous; Injections, Subcutaneous; Leukemia; Lymphocytes | 1986 |
[Therapeutic effects of a combination of intermediate-dose cytosine arabinoside, adriamycin and vincristine in relapsed acute leukemia].
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Doxorubicin; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Leukemia; Male; Middle Aged; Recurrence; Vincristine | 1987 |
[Treatment of a case of childhood acute non-lymphocytic leukemia (ANLL) using high-dose cytosine arabinoside for intensification of early therapy].
Topics: Aclarubicin; Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Administration Schedule; Female; Humans; Leukemia; Methotrexate; Naphthacenes; Vincristine | 1987 |
High-dose, continuous-infusion cyclophosphamide, cytarabine, vincristine, and prednisone for remission induction in refractory adult acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Female; Hematologic Diseases; Humans; Leukemia; Male; Middle Aged; Prednisone; Vincristine | 1987 |
Abrogation of the prognostic significance of low leukemic cell retention of cytosine arabinoside triphosphate by intensification of therapy and by alteration in the dose and schedule of administration of cytosine arabinoside.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Bone Marrow; Cytarabine; Doxorubicin; Humans; Leukemia; Middle Aged; Neoplasm Proteins; Phosphorylation; Prognosis | 1987 |
[Modified VAPA therapy in children with acute nonlymphocytic leukemia].
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Doxorubicin; Female; Humans; Infant; Leukemia; Male; Methotrexate; Methylprednisolone; Metoclopramide; Prognosis; Remission Induction; Vincristine | 1986 |
[Patient with hypoplastic leukemia successfully treated with N4-palmitoyl-1-beta-D-arabinofuranosyl cytosine].
Topics: Aged; Cytarabine; Drug Administration Schedule; Humans; Leukemia; Male | 1985 |
[High dose cytosine arabinoside (HDCA) in children with refractory leukemia or malignant lymphoma (3 g/m2 vs 1.5 g/m2)].
Topics: Adolescent; Child; Cytarabine; Female; Humans; Kinetics; Leukemia; Lymphoma; Male | 1985 |
Combination amsacrine and high-dose cytosine arabinoside in acute leukemia.
Topics: Aminoacridines; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Leukemia | 1985 |
High-dose cytosine arabinoside and mAMSA induction and consolidation in patients with previously untreated de novo acute nonlymphocytic leukemia: Phase I Pilot Study for the Eastern Cooperative Oncology Group.
Topics: Aminoacridines; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Evaluation; Drug Resistance; Humans; Leukemia | 1985 |
Treatment of acute leukemia with amsacrine and high-dose cytarabine.
Topics: Acute Disease; Aminoacridines; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Diarrhea; Dose-Response Relationship, Drug; Humans; Leukemia; Nausea | 1985 |
Amsacrine with high-dose cytarabine in acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Aminoacridines; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Hematologic Diseases; Humans; Leukemia; Middle Aged | 1985 |
SQ chemotherapy at home.
Topics: Acute Disease; Cytarabine; Humans; Injections, Subcutaneous; Leukemia; Self Administration | 1985 |
Treatment of refractory leukemia with high-dose cytosine arabinoside.
Topics: Acute Disease; Adult; Aged; Cytarabine; Female; Humans; Leukemia; Leukemia, Myeloid; Male; Middle Aged | 1985 |
Chemotherapy of acute leukemia in adults.
Topics: Aclarubicin; Acute Disease; Adult; Antineoplastic Agents; Cytarabine; Doxorubicin; Drug Evaluation; Humans; Interferon Type I; Leukemia; Naphthacenes | 1985 |
[Induction of remission by sequential treatment with cytosine arabinoside (araC/high dose) and L-asparaginase].
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Cytarabine; Drug Administration Schedule; Female; Humans; Leukemia; Leukemia, Lymphoid; Male; Middle Aged; Podophyllotoxin | 1985 |
Low dose cytarabine in acute non-lymphoblastic leukemia or myelodysplastic syndrome: report of six cases and review of the literature.
Topics: Acute Disease; Aged; Anemia, Aplastic; Bone Marrow; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged; Recurrence | 1985 |
Leukemia relapse in long-term survivors of acute leukemia.
Topics: Actuarial Analysis; Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Child; Child, Preschool; Cytarabine; Daunorubicin; Female; Health Surveys; Humans; Infant; Japan; Leukemia; Leukemia, Lymphoid; Male; Mercaptopurine; Middle Aged; Nervous System Neoplasms; Prednisolone; Recurrence; Testicular Neoplasms | 1985 |
Low-dose cytosine arabinoside (Ara-C) therapy in the myelodysplastic syndromes and acute leukemia.
Topics: Acute Disease; Adult; Aged; Bone Marrow; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Injections, Subcutaneous; Leukemia; Leukemia, Myeloid; Male; Middle Aged; Preleukemia | 1985 |
Idarubicin alone or in combination with cytarabine and etoposide (3 + 3 + 5 protocol) in acute non-lymphoblastic leukaemia.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Idarubicin; Leukemia; Male; Middle Aged | 1985 |
Pharmacokinetics and cellular determinants of response to 1-beta-arabinofuranosylcytosine (ara-C).
Topics: Animals; Arabinofuranosylcytosine Triphosphate; Bone Marrow; Cytarabine; Dose-Response Relationship, Drug; Drug Resistance; Humans; Leukemia; Leukemia L1210; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mice; Mice, Inbred DBA | 1985 |
High-dose cytosine arabinoside in the treatment of resistant acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Child; Cytarabine; Drug Resistance; Female; Humans; Leukemia; Leukemia, Myeloid; Male; Middle Aged; Recurrence; Time Factors | 1985 |
Sequential high-dose cytosine arabinoside and L-asparaginase in childhood leukemia in relapse.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bacterial Infections; Child; Child, Preschool; Cytarabine; Female; Humans; Infant; Leukemia; Leukemia, Lymphoid; Male; Neutropenia; Recurrence; Thrombocytopenia | 1985 |
Evolution of clinical studies with high-dose cytosine arabinoside at the M.D. Anderson Hospital.
Topics: Arabinofuranosylcytosine Triphosphate; Chromosome Aberrations; Cytarabine; Drug Evaluation; Drug Resistance; Half-Life; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Prognosis; Time Factors | 1985 |
Sequential high-dose cytosine arabinoside-asparaginase treatment in advanced childhood leukemia.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cytarabine; Drug Evaluation; Female; Humans; Infant; Infusions, Parenteral; Injections, Intramuscular; Leukemia; Leukemia, Lymphoid; Male; Recurrence; Time Factors | 1985 |
[Gastrointestinal symptoms of aclacinomycin A in patients with adult acute nonlymphocytic leukemia--comparison of BH-AC-DMP therapy and BH-AC-AMP therapy].
Topics: Aclarubicin; Acute Disease; Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Digestive System; Female; Gastrointestinal Diseases; Humans; Leukemia; Male; Mercaptopurine; Naphthacenes; Prednisolone | 1985 |
Bone marrow response to chemotherapy in acute lymphocytic leukaemia and acute non-lymphocytic leukaemia.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Asparaginase; Bone Marrow; Bone Marrow Cells; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Humans; Leukemia; Leukemia, Lymphoid; Lymphocyte Depletion; Middle Aged; Plasma Cells; Prednisone; Thioguanine; Vincristine | 1985 |
[High-dose cytosine arabinoside administration in the treatment of refractory leukemia].
Topics: Adolescent; Adult; Cytarabine; Drug Administration Schedule; Female; Humans; Leukemia; Leukemia, Myeloid; Lymphoma; Male; Middle Aged | 1985 |
Comparison of autoradiography and DNA histograms in assessing S-phase cells from patients with myeloid leukemias.
Topics: Animals; Autoradiography; Bone Marrow; Cells, Cultured; Cytarabine; DNA Replication; DNA, Neoplasm; Doxorubicin; Flow Cytometry; Humans; Interphase; Leukemia; Leukemia P388; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphocytes; Mice | 1985 |
Cytosine arabinoside transport and metabolism in acute leukemias and T cell lymphoblastic lymphoma.
Topics: Adolescent; Adult; Aged; Arabinofuranosylcytosine Triphosphate; Biological Transport, Active; Biotransformation; Child; Child, Preschool; Cytarabine; Humans; In Vitro Techniques; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Middle Aged; T-Lymphocytes | 1985 |
[High-dose treatment].
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cytarabine; Daunorubicin; Doxorubicin; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Humans; Infusions, Parenteral; Leucovorin; Leukemia; Methotrexate; Neoplasms | 1985 |
Leukemogenesis and differentiation.
Topics: Animals; Antineoplastic Agents; Cell Differentiation; Clone Cells; Colony-Stimulating Factors; Cytarabine; Dexamethasone; Humans; Leukemia; Leukocytes; Mice | 1985 |
Continuous infusion of high-dose cytosine arabinoside for treatment of childhood acute leukemia and non-Hodgkin's lymphoma in relapse.
Topics: Acute Disease; Adolescent; Adult; B-Lymphocytes; Bacterial Infections; Burkitt Lymphoma; Cerebellar Ataxia; Child; Child, Preschool; Cytarabine; Female; Gastrointestinal Diseases; Humans; Leukemia; Leukemia, Lymphoid; Lymphoma; Male; Neutropenia; Recurrence; Thrombocytopenia | 1985 |
Double labeling of human leukemic cells using 3H-cytarabine and monoclonal antibody against bromodeoxyuridine.
Topics: Antibodies, Monoclonal; Autoradiography; Bone Marrow; Bromodeoxyuridine; Cells, Cultured; Cytarabine; DNA; Fluorescent Antibody Technique; Humans; Leukemia; Thymidine; Tritium; Tumor Stem Cell Assay | 1985 |
[Non-hematologic toxicity in high-dose cytarabine therapy].
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Brain Diseases; Cytarabine; Dose-Response Relationship, Drug; Humans; Keratitis; Leukemia; Skin Diseases; Vomiting | 1985 |
[High-dose cytarabine treatment in acute leukemias and leukemic meningiosis: clinical aspects and pharmacokinetics].
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Kinetics; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Meningeal Neoplasms; Middle Aged | 1985 |
[Experiences with HD-Ara C treatment in leukemia patients].
Topics: Acute Disease; Aminoacridines; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia; Leukemia, Myeloid, Acute | 1985 |
[Principles of high-dose cytarabinoside treatment].
Topics: Acute Disease; Bone Marrow; Cell Cycle; Cytarabine; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Resistance; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphoma; Metabolic Clearance Rate; RNA, Neoplasm | 1985 |
[Results of therapy with high-dose cytosine arabinoside].
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged | 1985 |
[High-dose cytosine arabinoside].
Topics: Acute Disease; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia | 1985 |
[Results of high-dose cytarabine therapy. A review].
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma | 1985 |
Remission from central nervous system involvement in adults with acute leukemia. Effect of intensive therapy and prognostic factors.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Humans; Hydrocortisone; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Meningeal Neoplasms; Methotrexate; Prognosis; Radiotherapy Dosage | 1985 |
Bone marrow transplantation for acute leukemia and lymphoma with high-dose cytosine arabinoside and total body irradiation.
Topics: Acute Disease; Adolescent; Adult; Bone Marrow Transplantation; Central Nervous System Diseases; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Diarrhea; Graft vs Host Disease; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphoma; Pulmonary Fibrosis; Skin Diseases; Whole-Body Irradiation | 1985 |
Central nervous system toxicity with high-dose cytosine arabinoside.
Topics: Acute Disease; Aging; Central Nervous System Diseases; Combined Modality Therapy; Cytarabine; Drug Evaluation; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphoma; Middle Aged; Whole-Body Irradiation | 1985 |
In vitro and in vivo assessment of sensitivity to ara-C in myeloid leukemias.
Topics: Adult; Aged; Bone Marrow; Bromodeoxyuridine; Cytarabine; DNA; Drug Resistance; Female; Fluorescent Antibody Technique; Humans; Immunoenzyme Techniques; Interphase; Leukemia; Leukemia, Myeloid; Male; Middle Aged | 1985 |
Summary overview of clinical session.
Topics: Acute Disease; Adult; Antineoplastic Agents; Bone Marrow Transplantation; Child; Cytarabine; Follow-Up Studies; HLA Antigens; Humans; Leukemia | 1985 |
Cytosine arabinoside, cyclophosphamide and total body irradiation conditioning regimens for bone marrow transplantation.
Topics: Adolescent; Adult; Anemia, Aplastic; Bone Marrow Transplantation; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Female; Graft Rejection; Humans; Immunosuppression Therapy; Infant; Leukemia; Male; Middle Aged; Multiple Myeloma; Whole-Body Irradiation | 1985 |
Double labeling and in vitro versus in vivo incorporation of bromodeoxyuridine in patients with acute nonlymphocytic leukemia.
Topics: Automation; Autoradiography; Bone Marrow Cells; Bromodeoxyuridine; Cell Cycle; Cytarabine; DNA, Neoplasm; Fluorescent Antibody Technique; Humans; Immunoenzyme Techniques; Leukemia; Thymidine | 1985 |
Transplantation of HLA-haploidentical T-cell-depleted marrow for leukemia: addition of cytosine arabinoside to the pretransplant conditioning prevents rejection.
Topics: Adolescent; Adult; Bone Marrow; Bone Marrow Cells; Bone Marrow Transplantation; Child; Cytarabine; Genotype; Graft Rejection; Graft vs Host Disease; Histocompatibility Testing; HLA Antigens; Humans; Immunosuppression Therapy; Leukemia; T-Lymphocytes | 1985 |
[Thrombocyte replacement in hematologic diseases].
Topics: Acute Disease; Adolescent; Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Blood Platelets; Blood Transfusion; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Daunorubicin; Disseminated Intravascular Coagulation; Doxorubicin; Fever; Hematologic Diseases; Hemorrhage; Histocompatibility; HLA Antigens; Humans; Leukemia; Leukemia, Myeloid, Acute; Middle Aged; Plateletpheresis | 1985 |
Results of therapy in adult acute nonlymphoblastic leukemia: experience in Jerusalem, Israel, during 1975-1982.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Israel; Leukemia; Middle Aged; Thioguanine; Time Factors | 1985 |
Low-dose cytarabine: persistence of a clonal abnormality during complete remission of acute nonlymphocytic leukemia.
Topics: Acute Disease; Aged; Chromosome Aberrations; Clone Cells; Cytarabine; Humans; Leukemia; Male; Metaphase; Y Chromosome | 1986 |
Low-dose cytosine arabinoside therapy in a patient with myelofibrosis during transformation to acute non-lymphocytic leukemia.
Topics: Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia; Lymphocyte Activation; Male; Middle Aged; Primary Myelofibrosis | 1986 |
[Etoposide (VP 16/NK 171) and cytosine arabinoside combination chemotherapy in refractory childhood leukemia].
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Drug Administration Schedule; Etoposide; Female; Humans; Infant; Leukemia; Lymphoma; Male; Myeloproliferative Disorders; Podophyllotoxin | 1986 |
Cerebrospinal fluid concentrations of cytosine arabinoside during intravenous therapy with intermediate dose: a preliminary report.
Topics: Acute Disease; Adolescent; Adult; Cytarabine; Humans; Infusions, Parenteral; Leukemia; Male | 1985 |
Clinical evidence of a cumulative effect of high-dose cytarabine on the cerebellum in patients with acute leukemia: a leukemia intergroup report.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Diseases; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged | 1985 |
Low-dose cytosine arabinoside treatment for acute nonlymphocytic leukemia in elderly patients.
Topics: Acute Disease; Aged; Ambulatory Care; Bone Marrow; Cytarabine; Hematologic Diseases; Humans; Injections, Subcutaneous; Leukemia; Nausea; Recurrence | 1985 |
Pharmacokinetics of 1-beta-D-arabinofuranosylcytosine 5'-triphosphate in leukemic cells after intravenous and subcutaneous administration of 1-beta-D-arabinofuranosylcytosine.
Topics: Aged; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cytarabine; Female; Humans; Injections, Intravenous; Injections, Subcutaneous; Kinetics; Leukemia; Male; Middle Aged; Phosphorylation | 1985 |
Low-dose cytarabine: chromosomal findings suggesting its cytostatic as well as differentiating effect.
Topics: Aged; Bone Marrow; Cell Differentiation; Chromosome Aberrations; Cytarabine; Humans; Leukemia; Male | 1985 |
Low dose cytosine arabinoside in the treatment of acute non-lymphocytic leukaemia.
Topics: Acute Disease; Adult; Aged; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia; Male; Middle Aged | 1985 |
Clinical pharmacology of low-dose cytosine arabinoside.
Topics: Acute Disease; Cytarabine; Delayed-Action Preparations; Dose-Response Relationship, Drug; Humans; Infusions, Parenteral; Leukemia; Preleukemia; Radioimmunoassay | 1985 |
High-dose cytosine arabinoside and daunorubicin as consolidation therapy for acute nonlymphocytic leukemia in first remission: a pilot study.
Topics: Acute Disease; Adolescent; Adult; Aged; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leukemia; Life Expectancy; Male; Middle Aged; Recurrence | 1985 |
How much is too much high-dose cytosine arabinoside?
Topics: Adult; Central Nervous System Diseases; Cytarabine; Gastrointestinal Diseases; Humans; Length of Stay; Leukemia; Meningeal Neoplasms; Pulmonary Edema | 1985 |
Cerebellar toxicity following high-dose cytosine arabinoside.
Topics: Ataxia; Cerebellar Diseases; Cytarabine; Dysarthria; Humans; Leukemia; Male; Middle Aged; Purkinje Cells | 1985 |
Monitoring the remission induction therapy of acute nonlymphoblastic leukemia by bone marrow cell culture criteria.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cells, Cultured; Colony-Forming Units Assay; Cytarabine; Daunorubicin; Humans; Leukemia; Monitoring, Physiologic; Thioguanine | 1985 |
[Myelodysplastic syndromes].
Topics: Acute Disease; Androgens; Cytarabine; Glucocorticoids; Hemorrhage; Humans; Immunotherapy; Infections; Leukemia; Myelodysplastic Syndromes; Prognosis; Vitamins | 1985 |
Inhibition of 1-beta-D-arabinofuranosylcytosine transport and net accumulation by teniposide and etoposide in Ehrlich ascites cells and human leukemic blasts.
Topics: Animals; Binding Sites; Biological Transport; Carcinoma, Ehrlich Tumor; Cells, Cultured; Cytarabine; Etoposide; Humans; Leukemia; Male; Mice; Mice, Inbred Strains; Podophyllotoxin; Teniposide; Thioinosine; Tritium | 1985 |
Response of therapy-associated acute nonlymphocytic leukemia to intensive induction chemotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Doxorubicin; Female; Humans; Leukemia; Leukemia, Radiation-Induced; Male; Middle Aged; Neoplasms; Prednisone; Prognosis; Thioguanine; Vincristine | 1985 |
High-dose cytosine arabinoside and daunomycin as primary therapy for adults with acute nonlymphoblastic leukemia: a pilot study.
Topics: Adolescent; Adult; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Infections; Leukemia; Middle Aged | 1985 |
Treatment of leukemia with low-dose ara-C: a study of 160 cases.
Topics: Acute Disease; Aged; Aging; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia | 1985 |
Pharmacologically directed ara-C therapy for refractory leukemia.
Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cytarabine; DNA; Drug Resistance; Humans; Kinetics; Leukemia | 1985 |
Low-dose cytosine arabinoside in the treatment of acute nonlymphoblastic leukemia and myelodysplastic syndromes.
Topics: Acute Disease; Adult; Aged; Bone Marrow; Bone Marrow Diseases; Cells, Cultured; Cytarabine; Granulocytes; Hematopoiesis; Humans; Leukemia; Middle Aged; Syndrome | 1985 |
Intensive postremission therapy in adults with acute nonlymphocytic leukemia with ara-C by continuous infusion or bolus administration: preliminary results of a CALGB phase I study.
Topics: Adolescent; Adult; Aged; Cytarabine; Drug Evaluation; Drug Resistance; Female; Humans; Leukemia; Male; Middle Aged | 1985 |
Drug sensitivity test for patients with acute leukemia on high-dose ara-C therapy.
Topics: Cytarabine; DNA; Dose-Response Relationship, Drug; Drug Resistance; Humans; In Vitro Techniques; Leukemia | 1985 |
The treatment of patients with acute nonlymphocytic leukemia in remission.
Topics: Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Cytarabine; Humans; Kinetics; Leukemia; Prognosis; Recurrence; Time Factors | 1985 |
Effect of 1-beta-D-arabinofuranosyl cytosine and hydroxyurea on the repair of X-ray-induced DNA single-strand breaks in human leukemic blasts.
Topics: Cells, Cultured; Cytarabine; DNA; DNA Repair; DNA, Single-Stranded; Humans; Hydroxyurea; Leukemia; X-Rays | 1985 |
Meningeal involvement in patients with acute nonlymphocytic leukemia. Incidence, management, and predictive factors.
Topics: Actuarial Analysis; Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Prognosis | 1985 |
Modulation of 1-beta-D-arabinofuranosylcytosine metabolism by thymidine in human acute leukemia.
Topics: Acute Disease; Cytarabine; Deoxycytosine Nucleotides; DNA; Drug Interactions; Drug Therapy, Combination; Humans; Leukemia; Thymidine; Thymine Nucleotides | 1985 |
Central nervous system toxicity with high-dose Ara-C.
Topics: Adolescent; Adult; Aged; Brain Diseases; Central Nervous System Diseases; Cerebellar Diseases; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged | 1985 |
Terminal deoxynucleotidyl transferase-positive acute leukemias evolving from a myelodysplastic syndrome.
Topics: Acute Disease; Adult; Cytarabine; DNA Nucleotidylexotransferase; DNA Nucleotidyltransferases; Humans; Leukemia; Myeloproliferative Disorders; Preleukemia | 1985 |
Low-dose arabinosyl cytosine in acute leukemia after a myelodysplastic syndrome and in elderly leukemia.
Topics: Acute Disease; Adult; Aged; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia; Middle Aged; Myeloproliferative Disorders; Preleukemia | 1985 |
Relationship between leukemic cell retention of cytosine arabinoside triphosphate and the duration of remission in patients with acute non-lymphocytic leukemia.
Topics: Acute Disease; Adult; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged; Phosphorylation; Time Factors | 1985 |
Daunomycin administered by continuous intravenous infusion is effective in the treatment of acute nonlymphocytic leukaemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Humans; Infusions, Parenteral; Leukemia; Middle Aged; Thioguanine; Time Factors | 1985 |
Outcome of aggressive induction therapy in acute non-lymphocytic leukaemia.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia; Male; Mercaptopurine; Prednisolone; Vincristine | 1985 |
Favourable remission rate by repeating low dose ARA-C treatment in ANLL and RAEB.
Topics: Acute Disease; Adolescent; Adult; Aged; Anemia, Aplastic; Bone Marrow; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged | 1985 |
Treatment of acute nonlymphocytic leukemia in young and elderly patients.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Daunorubicin; Female; Humans; Leukemia; Male; Middle Aged; Prognosis; Recurrence; Sex Factors; Vincristine | 1985 |
Subacute pulmonary failure complicating therapy with high-dose Ara-C in acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Cytarabine; Drug Evaluation; Female; Humans; Leukemia; Lung Diseases; Male; Middle Aged; Pulmonary Edema; Respiratory Insufficiency | 1985 |
Relationship of 1-beta-D-arabinofuranosylcytosine in plasma to 1-beta-D-arabinofuranosylcytosine 5'-triphosphate levels in leukemic cells during treatment with high-dose 1-beta-D-arabinofuranosylcytosine.
Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cytarabine; Humans; Kinetics; Leukemia | 1985 |
Treatment of dysmyelopoietic/leukemic syndromes with myelofibrosis and megakaryocytic hyperplasia with large doses of cytosine arabinoside.
Topics: Acute Disease; Adult; Aged; Biopsy; Blood Cell Count; Bone Marrow; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Hyperplasia; Leukemia; Male; Megakaryocytes; Middle Aged; Myelodysplastic Syndromes; Pancytopenia; Primary Myelofibrosis; Thrombocythemia, Essential | 1985 |
Low-dose Ara-C in treatment of overt acute leukaemia.
Topics: Acute Disease; Cytarabine; Humans; Leukemia | 1985 |
Intrathecal methotrexate.
Topics: Central Nervous System; Cytarabine; Humans; Hydrogen-Ion Concentration; Injections, Spinal; Leukemia; Methotrexate; Osmolar Concentration | 1972 |
[Cytostatics in hematology].
Topics: Antineoplastic Agents; Asparaginase; Cell Division; Chemistry; Culture Techniques; Cytarabine; Daunorubicin; Depression, Chemical; DNA; Drug Combinations; Drug Resistance; Germ-Free Life; Half-Life; History, 20th Century; Hodgkin Disease; Humans; Leukemia; Lymphatic Diseases; Mercaptopurine; Remission, Spontaneous; Stimulation, Chemical; Thioguanine | 1972 |
Combination chemotherapy: rationale for schedule selection and use of agents with independent toxicities in phase I and II clinical trials.
Topics: Acute Disease; Adult; Agranulocytosis; BCG Vaccine; Bleomycin; Cytarabine; Doxorubicin; Drug Combinations; Humans; Immunosuppression Therapy; Leukemia; Lymphopenia; Mitosis; Nitrogen Mustard Compounds; Prednisone; Thrombocytopenia; Vincristine | 1973 |
[Acute undifferentiated leukemia--acute lymphocytic leukemia of adults. Differential diagnosis, prognosis, results of therapy].
Topics: Acute Disease; Adult; Age Factors; Aged; Aminosalicylic Acids; Asparaginase; Cytarabine; Cytodiagnosis; Cytoplasm; Daunorubicin; Diagnosis, Differential; Drug Therapy, Combination; Female; Glycogen; Histocytochemistry; Humans; Leukemia; Leukemia, Lymphoid; Male; Methotrexate; Middle Aged; Prognosis; Staining and Labeling; Vincristine | 1974 |
Adult acute leukaemia.
Topics: Acute Disease; Administration, Oral; Adult; Aged; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Cytosine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Humans; Injections, Intravenous; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Middle Aged; Prednisone; Remission, Spontaneous; Staining and Labeling; Thioguanine; Vincristine | 1974 |
Allogeneic marrow grafts in man using cyclophosphamide.
Topics: Amidines; Bone Marrow; Bone Marrow Cells; Bone Marrow Transplantation; Cyclophosphamide; Cytarabine; Cytomegalovirus; Graft vs Host Disease; Graft vs Host Reaction; Herpesviridae; Histocompatibility Testing; Humans; Immunologic Deficiency Syndromes; Injections, Spinal; Karyotyping; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukocyte Count; Lymphocyte Culture Test, Mixed; Methotrexate; Phenyl Ethers; Pneumonia; Prednisone; Transplantation Immunology; Transplantation, Homologous | 1974 |
Bone-marrow transplantation following combination chemotherapy immunosuppression (B.A.C.T.) in patients with acute leukemia.
Topics: ABO Blood-Group System; Acute Disease; Blood Group Incompatibility; Bone Marrow Cells; Bone Marrow Transplantation; Child; Chimera; Cyclophosphamide; Cytarabine; Drug Resistance; Drug Therapy, Combination; Female; Graft vs Host Reaction; Histocompatibility; Humans; Leukemia; Leukemia, Lymphoid; Male; Methotrexate; Nitrosourea Compounds; Thioguanine; Transplantation, Homologous | 1974 |
Studies on a new mechanism of resistance of L5178Y murine leukemia cells to cytosine arabinoside.
Topics: Animals; Chromosomes; Culture Techniques; Cytarabine; Cytosine Nucleotides; Depression, Chemical; Hydrogen-Ion Concentration; Leukemia; Leukemia Virus, Murine; Leukemia, Experimental; Mice; Mutation; Nucleosides; Nucleotides; Solubility; Staining and Labeling; Thymidine; Tritium; Uridine | 1968 |
[The acute leukemia in adults, therapy and prognosis].
Topics: Acute Disease; Adolescent; Adult; Aged; Cyclophosphamide; Cytarabine; Drug Resistance, Microbial; Female; Humans; Leukemia; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Prognosis; Vincristine | 1969 |
[Activity of methionine synthetase (5-methyl-5,6,7,8-tetrahydrofolate: homocysteine methyltransferase) as a proliferation parameter in growing cells].
Topics: Cell Division; Cells, Cultured; Cytarabine; DNA Nucleotidyltransferases; Folic Acid; Humans; In Vitro Techniques; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Methionine; Methyltransferases; Prednisolone; Tetrahydrofolates; Thioguanine; Thymidine Kinase; Vincristine | 1973 |
[Therapy of acute leukoses].
Topics: Acute Disease; Adult; Antineoplastic Agents; Asparaginase; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Infection Control; Leukemia; Life Expectancy; Male; Mercaptopurine; Methotrexate; Middle Aged; Patient Isolators; Prednisolone; Thioguanine; Time Factors; Vincristine | 1973 |
Treatment of central nervous system leukemia with intrathecal cytosine arabinoside.
Topics: Adolescent; Adult; Animals; Brain Neoplasms; Child; Child, Preschool; Cytarabine; Dogs; Female; Haplorhini; Headache; Humans; Injections, Spinal; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphoma, Non-Hodgkin; Male; Meninges; Middle Aged; Vomiting | 1973 |
Macroglobulinemia in a child with acute leukemia.
Topics: Bence Jones Protein; Bone Marrow Cells; Child; Chromatography, Gel; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Electrophoresis; Fluorescent Antibody Technique; Humans; Immune Sera; Immunoelectrophoresis; Immunoglobulin Fab Fragments; Immunoglobulin Fc Fragments; Injections, Spinal; Leukemia; Male; Mercaptopurine; Methotrexate; Microscopy, Electron; Prednisone; Vincristine; Waldenstrom Macroglobulinemia | 1974 |
Human leukemia antigens: partial isolation and characterization.
Topics: Animals; Antigens, Neoplasm; Cell Line; Cell Membrane; Centrifugation; Chromatography, Gel; Cycloheximide; Cytarabine; Cytotoxicity Tests, Immunologic; Dactinomycin; Haplorhini; Histocompatibility Antigens; Humans; Immune Sera; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Lymphocytes; Microscopy, Electron; Neuraminidase; Papain; Potassium Chloride; Pronase; Puromycin; Rabbits; Subcellular Fractions; Temperature; Trypsin | 1974 |
Immunoglobulins in acute leukemia in children.
Topics: Adolescent; Bone Marrow; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Female; Humans; Immunodiffusion; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Immunoglobulins; Infant; Leukemia; Leukemia, Myeloid; Lymphocytes; Male; Mercaptopurine; Methotrexate; Prednisone; Vincristine | 1974 |
Studies of cellular proliferation in human leukemia. 3. Behavior of leukemic cells in three adults with acute leukemia given continuous infusions of 3H-thymidine for 8 or 10 days.
Topics: Acute Disease; Adult; Aged; Autoradiography; Bone Marrow; Bone Marrow Cells; Cell Division; Cell Nucleus; Culture Techniques; Cytarabine; Down Syndrome; Female; Floxuridine; Humans; Karyotyping; Leukemia; Leukocytes; Lymphocytes; Male; Mitosis; Prednisone; Thioguanine; Thymidine; Tritium; Vincristine | 1970 |
Acute leukemia and infection.
Topics: Acute Disease; Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Agranulocytosis; Aspergillosis; Candidiasis; Cytarabine; Female; Humans; Leukemia; Male; Mercaptopurine; Methotrexate; Middle Aged; Mucormycosis; Nocardia Infections; Prednisone; Proteus Infections; Pseudomonas Infections; Sepsis; Staphylococcal Infections; Strongyloidiasis; Uracil; Vinblastine | 1967 |
Interferon production by human leukocytes in vitro: some biological characteristics.
Topics: Antimetabolites; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Culture Techniques; Cytarabine; Dactinomycin; DNA, Viral; Humans; Interferons; Leukemia; Leukocytes; Parainfluenza Virus 1, Human; Phenylalanine; Puromycin; Thymidine; Uridine; Virus Cultivation; Virus Replication | 1969 |
The child with acute leukemia.
Topics: Age Factors; Asparaginase; Chickenpox; Child, Preschool; Counseling; Cyclophosphamide; Cytarabine; Cytomegalovirus Infections; Daunorubicin; Drug-Related Side Effects and Adverse Reactions; Humans; Injections, Spinal; Leukemia; Mercaptopurine; Methotrexate; Patient Care Planning; Pediatrics; Physician-Patient Relations; Prednisone; Prognosis; Sex Factors; Vincristine | 1974 |
Letter: Febrile response to cytarabine.
Topics: Acute Disease; Adult; Cytarabine; Female; Fever; Humans; Leukemia | 1974 |
[Therapeutic experience in acute infantile leukosis].
Topics: Antineoplastic Agents; Betamethasone; Child; Child, Preschool; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Prednisone | 1974 |
Daunorubicin-DNA: further clinical trials in acute non-lymphoblastic leukemia.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Cytarabine; Daunorubicin; DNA; Drug Combinations; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Middle Aged; Remission, Spontaneous; Vincristine | 1974 |
[Treatment of adult acute leukemia with a combination of cytosine arabinoside, vincristine, 6-mercaptopurine, prednisolone, and L-asparaginase (author's transl)].
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Agents; Asparaginase; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Mercaptopurine; Middle Aged; Prednisolone; Vincristine | 1974 |
[Anhydro-arabinosylcytosine (cyclocytidine) in the therapy of acute leukemia].
Topics: Acute Disease; Adolescent; Adult; Aged; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged | 1974 |
DCMP therapy in acute leukemia--the experimental and clinical study.
Topics: Acute Disease; Adult; Animals; Child; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia; Leukemia L1210; Mercaptopurine; Prednisolone; Time Factors | 1974 |
Adriamycin in the treatment of acute leukaemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Resistance; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Middle Aged; Remission, Spontaneous | 1972 |
Combination chemotherapy of adult acute nonlymphoblastic leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Bone Marrow; Cytarabine; Drug Synergism; Female; Humans; Hydroxyurea; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Nausea; Remission, Spontaneous; Thioguanine; Vomiting | 1972 |
[Experience in the therapy of acute leukemia in the period from March, 1959 to February, 1971].
Topics: Adolescent; Adult; Asparaginase; Child; Child, Preschool; Cytarabine; Evaluation Studies as Topic; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Remission, Spontaneous; Vincristine | 1972 |
Serum muramidase levels in acute leukemia.
Topics: Adult; Aged; Blood Cell Count; Bone Marrow Cells; Bone Marrow Examination; Child; Cytarabine; Densitometry; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Muramidase; Remission, Spontaneous; Thioguanine; Vincristine | 1972 |
[Effect of daunomycin and adriamycin in cytostatic combination therapy of acute leukoses of the adult].
Topics: Acute Disease; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Blood Coagulation Disorders; Bone Marrow Diseases; Carbenicillin; Cytarabine; Daunorubicin; Drug Synergism; Female; Glycosides; Hair; Heart Diseases; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisolone; Remission, Spontaneous; Skin Diseases; Vincristine | 1972 |
Prediction of the response of patients with acute nonlymphocytic leukemia to cytosine arabinoside (NSC-63878) therapy.
Topics: Adult; Aged; Cytarabine; Female; Humans; Kinetics; Leukemia; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukocyte Count; Leukocytes; Male; Middle Aged; Remission, Spontaneous; Thymidine; Tritium | 1972 |
The outlook for the adult with acute leukaemia, 1972.
Topics: Acute Disease; Adolescent; Adult; Aged; Bacterial Infections; Cytarabine; Drug Combinations; Female; Hemorrhage; Humans; Hydroxyurea; Length of Stay; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Patient Isolators; Prednisone; Remission, Spontaneous; Thioguanine | 1972 |
[Successful intrathecal treatment of meningeal leukaemia with methotrexate in the adult].
Topics: Adult; Blood-Brain Barrier; Cortisone; Cytarabine; Female; Humans; Injections, Spinal; Leukemia; Leukemia, Lymphoid; Meninges; Methotrexate; Prednisone; Time Factors | 1973 |
Acute leukemia presenting as a breast mass.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Biopsy, Needle; Breast Neoplasms; Child; Cytarabine; Daunorubicin; Diagnosis, Differential; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Menarche; Mercaptopurine; Methotrexate; Prednisolone; Sulfates; Vincristine | 1973 |
Optimism in leukemia treatment.
Topics: Acute Disease; Adult; Child; Cyclophosphamide; Cytarabine; Humans; Hydroxyurea; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Prednisolone; Thioguanine; Vincristine | 1973 |
[Otitis and leukemia].
Topics: Adult; Antineoplastic Agents; Cytarabine; Daunorubicin; Ear Neoplasms; Gentamicins; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Otitis; Otitis Externa; Punctures | 1973 |
Refractory leukemia treated with cytosine arabinoside and cyclophosphamide.
Topics: Adolescent; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Evaluation Studies as Topic; Female; Humans; Infant; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Prednisone; Remission, Spontaneous; Vincristine | 1973 |
Treatment of acute myeloid leukaemia according to the Hammersmith protocol: preliminary report.
Topics: Adolescent; Adult; Age Factors; Aged; Child; Cytarabine; Daunorubicin; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; London; Middle Aged; Prednisolone; Remission, Spontaneous; Thioguanine | 1973 |
Comparative chemotherapy of AKR lymphoma and human hematological neoplasia.
Topics: Animals; Antineoplastic Agents; Biological Assay; Carmustine; Cyclohexanes; Cyclophosphamide; Cytarabine; Daunorubicin; Disease Models, Animal; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Fluorouracil; Hodgkin Disease; Humans; Leukemia; Leukemia L1210; Leukemia, Experimental; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma; Male; Mechlorethamine; Melphalan; Mice; Mice, Inbred AKR; Multiple Myeloma; Nitrosourea Compounds; Prednisone; Remission, Spontaneous; Vinblastine; Vincristine | 1974 |
Adult acute leukaemia--a suitable case for treatment?
Topics: Acute Disease; Adult; Aged; Agranulocytosis; Anemia; Blood Platelet Disorders; Blood Transfusion; Bone Marrow Diseases; Cytarabine; Daunorubicin; Female; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Mouth Diseases; Ulcer | 1973 |
Complications of cytostatic therapy in childhood leukemia.
Topics: Adrenal Cortex Hormones; Antineoplastic Agents; Asparaginase; Autopsy; Brain Neoplasms; Child; Child, Preschool; Cytarabine; Female; Humans; Infant; Kidney Neoplasms; Leukemia; Leukemia, Myeloid; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Time Factors | 1973 |
Eventual control of clinical leukemia.
Topics: Administration, Oral; Africa; Burkitt Lymphoma; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Injections, Spinal; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate; Prednisone; United States; Vincristine | 1973 |
Agar culture studies in 127 cases of untreated acute leukemia: the prognostic value of reclassification of leukemia according to in vitro growth characteristics.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Bone Marrow; Bone Marrow Cells; Cell Division; Cells, Cultured; Child; Clone Cells; Cytarabine; Daunorubicin; Densitometry; Drug Therapy, Combination; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Middle Aged; Prognosis; Remission, Spontaneous; Vincristine | 1974 |
Serial studies of immunocompetence of patients undergoing chemotherapy for acute leukemia.
Topics: Adolescent; Adult; Aged; Antibody Formation; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Follow-Up Studies; Humans; Hypersensitivity, Delayed; Immunotherapy; In Vitro Techniques; Lectins; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphocyte Activation; Lymphocytes; Middle Aged; Prednisone; Prognosis; Remission, Spontaneous; Skin Tests; Streptolysins; Vincristine | 1974 |
[Cytosine-arabinoside in the treatment of acute leukemias].
Topics: Acute Disease; Adolescent; Adult; Aged; Child; Child, Preschool; Cytarabine; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Middle Aged; Polycythemia | 1972 |
Proceedings: Treatment of acute leukaemia in adults.
Topics: Acute Disease; Adult; Allopurinol; Anti-Bacterial Agents; Bacterial Infections; Child; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Hydroxyurea; Leukemia; Leukemia, Lymphoid; Metabolic Diseases; Prednisone; Remission, Spontaneous; Thioguanine; Uric Acid; Vincristine | 1974 |
Prognosis of acute leukaemia in adults.
Topics: Acute Disease; Adult; Age Factors; Antineoplastic Agents; Child; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Middle Aged; Prednisolone; Prognosis; Remission, Spontaneous; Thioguanine; Vincristine | 1974 |
Blood and neoplastic diseases. Rational approach to the chemotherapy of human malignant disease-II.
Topics: Antineoplastic Agents; Brain Neoplasms; Busulfan; Cell Count; Cell Division; Cytarabine; Diffusion; Drug Tolerance; Hodgkin Disease; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukocyte Count; Lymphoma; Methotrexate; Multiple Myeloma; Neoplasms; Vincristine | 1974 |
[Neuroleukemia].
Topics: Adolescent; Adult; Child; Child, Preschool; Cytarabine; Humans; Leukemia; Leukemia, Lymphoid; Meninges; Methotrexate; Nervous System Diseases; Radioisotope Teletherapy; Remission, Spontaneous | 1974 |
Comparative results obtained in the treatment of acute leukemia.
Topics: Antineoplastic Agents; Asparaginase; Carmustine; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Hydroxyurea; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Meningitis; Methotrexate; Prednisone; Thioguanine; Vincristine | 1973 |
Symptomatic disorders of cardiac conduction in childhood leukemia.
Topics: Arrhythmias, Cardiac; Bradycardia; Child; Cyclophosphamide; Cytarabine; Female; Heart Block; Humans; Leukemia; Leukemia, Myeloid; Male; Myocardium; Prednisolone; Vincristine | 1974 |
Proceedings: Cellular kinetics in acute leukemia.
Topics: Acute Disease; Asparaginase; Cell Division; Cell Survival; Cytarabine; DNA; Glucocorticoids; Humans; Leukemia; Methotrexate; Mitosis; Thymidine; Tritium; Vincristine | 1972 |
Treatment of the acute leukemias.
Topics: Adjuvants, Immunologic; Asparaginase; Bacterial Vaccines; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Synergism; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Mycobacterium bovis; Prednisone; Remission, Spontaneous; Thioguanine; Vincristine | 1972 |
Marrow grafting and immunotherapy in identical twins with hematologic malignancies.
Topics: Adolescent; Adult; Antigens, Neoplasm; Bone Marrow Cells; Bone Marrow Transplantation; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Diseases in Twins; Humans; Immunotherapy; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphocyte Transfusion; Transplantation, Homologous | 1973 |
Influence of chemotherapeutic agents on the antibacterial activity of normal and leukemic sera.
Topics: Antineoplastic Agents; Blood Bactericidal Activity; Carmustine; Cell Membrane; Complement System Proteins; Cyclophosphamide; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Escherichia coli; Fluorouracil; Humans; Immunoglobulins; Leukemia; Mechlorethamine; Methotrexate; Microbial Sensitivity Tests; Muramidase; Prednisone; Vincristine | 1974 |
Biochemical techniques for classification of leukemic cell types.
Topics: Cytarabine; Cytological Techniques; DNA, Neoplasm; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Phosphorus | 1973 |
[Experimental and clinical studies on the combined use of cytosine arabinoside and vincristine in the treatment of leukemia].
Topics: Animals; Cytarabine; Drug Synergism; Humans; Leukemia; Lymphoma, Non-Hodgkin; Mice; Vincristine | 1972 |
[Cytarabine: mechanism of action and clinical application].
Topics: Cytarabine; DNA Nucleotidyltransferases; Humans; Immunosuppression Therapy; Leukemia; Mitosis | 1972 |
[The role of cytarabine in polychemotherapy of leukemia].
Topics: Asparaginase; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Synergism; Female; Humans; Leukemia; Male; Nitrosourea Compounds; Thioguanine; Vincristine | 1972 |
[Preliminary results of cytosine arabinoside therapy in various chemotherapeutic combinations in acute leukemias].
Topics: Acute Disease; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Combinations; Drug Interactions; Drug Synergism; Humans; Leukemia; Mercaptopurine; Prednisone; Thioguanine | 1972 |
Antagonism between inhibitors of DNA synthesis.
Topics: Animals; Body Weight; Cytarabine; Drug Combinations; Leukemia; Male; Meninges; Methotrexate; Mice; Mice, Inbred CBA; Rats; Rats, Inbred Strains | 1972 |
[The effect of cytosine arabinoside on cell kinetics in adult acute leukemia and its correlation to the therapeutic response].
Topics: Acute Disease; Adolescent; Adult; Bone Marrow; Bone Marrow Cells; Cell Count; Cytarabine; Erythropoiesis; Female; Humans; Injections, Intravenous; Leukemia; Male; Middle Aged; Mitosis | 1972 |
[Quadruple combination chemotherapy of acute leukemia using daunomycin, cytosine arabinoside, 6-mercaptopurine riboside and prednisolone].
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Cytarabine; Daunorubicin; Humans; Injections, Intravenous; Leukemia; Mercaptopurine; Middle Aged; Prednisolone | 1972 |
[Clinical advances in chemotherapy of leukemia].
Topics: Adult; Antineoplastic Agents; Cytarabine; Fluorouracil; Humans; Leukemia; Male; Mitomycins | 1972 |
[Mechanism of inactivation of cytosine arabinoside in human leukemic leukocytes in relation to clinical effects of the agent].
Topics: Cytarabine; Deamination; Humans; Leukemia; Leukocytes | 1972 |
[Acute leukemia - our therapeutic methods].
Topics: Adrenal Cortex Hormones; Adult; Cytarabine; Humans; Leukemia; Male; Mercaptopurine; Vincristine | 1972 |
Pharmacological disposition in mice of O 2 :2'-anhydro-1- -D-arabinosylcytosine 3'-phosphate, a potential antileukemic agent.
Topics: Anhydrides; Animals; Antineoplastic Agents; Carbon Isotopes; Chromatography, Ion Exchange; Chromatography, Paper; Cytarabine; Electrophoresis; Female; Leukemia; Mice; Mice, Inbred DBA; Phosphates; Rats; Time Factors | 1973 |
Cecal necrosis and perforation with systemic chemotherapy.
Topics: Adult; Asparaginase; Breast Neoplasms; Cecal Diseases; Child; Cytarabine; Daunorubicin; Female; Fluorouracil; Humans; Intestinal Perforation; Leukemia; Male; Mercaptopurine; Methotrexate; Middle Aged; Necrosis; Prednisone; Thioguanine; Vincristine | 1973 |
[Cytarabine (Alexan) for induction and intermediate therapy of acute leukemia in children and adolescents with special reference to oral administration].
Topics: Administration, Oral; Adolescent; Child; Cytarabine; Humans; Leukemia | 1973 |
[Polychemotherapy of acute leukemias in children and young persons].
Topics: Acute Disease; Adolescent; Ambulatory Care; Antineoplastic Agents; Asparaginase; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Humans; Immunotherapy; Leukemia; Mercaptopurine; Methotrexate; Prednisolone; Vincristine | 1973 |
Host defense, chemical immunosuppression, and the transplant recipient. Relative effects of intermittent versus continuous immunosuppressive therapy with reference to the objectives of treatment.
Topics: Antibody Formation; Antigens, Bacterial; Antigens, Fungal; Arthrodermataceae; Candida; Cyclophosphamide; Cytarabine; Drug Combinations; Hemocyanins; Humans; Hypersensitivity, Delayed; Immunity; Immunosuppressive Agents; Leukemia; Lymphocyte Activation; Mumps; Prednisone; Remission, Spontaneous; Skin Tests; Streptodornase and Streptokinase; Transplantation Immunology; Vincristine | 1973 |
[Combination chemotherapy with cytosine arabinoside and daunomycin in childhood acute leukemia].
Topics: Acute Disease; Child; Child, Preschool; Cytarabine; Daunorubicin; Female; Humans; Infant; Leukemia; Male | 1973 |
Chemotherapy of malignant lymphoma with adriamycin.
Topics: Cyclophosphamide; Cytarabine; Doxorubicin; Drug Therapy, Combination; Hematopoietic System; Hodgkin Disease; Humans; Injections, Intravenous; Leukemia; Lymphoma; Prednisone; Remission, Spontaneous; Vincristine | 1973 |
Proceedings: Management of acute leukemia.
Topics: Acute Disease; Adult; Cyclophosphamide; Cytarabine; Drug Synergism; Drug Therapy, Combination; Humans; Leukemia; Prednisone; Remission, Spontaneous; Vincristine | 1972 |
Cell kinetic patterns in human acute leukemia-evidence for control mechanisms.
Topics: Acute Disease; Bone Marrow; Bone Marrow Cells; Cell Division; Cell Survival; Cytarabine; Humans; Leukemia; Methotrexate; Mitosis; Radiation Effects; Vincristine | 1973 |
An analysis of the relationship of leukemic cell kinetics to chemotherapy.
Topics: Bone Marrow; Bone Marrow Cells; Cytarabine; Daunorubicin; DNA; Drug Therapy, Combination; Hematopoietic Stem Cells; Humans; Kinetics; Leukemia; Methotrexate; Mitosis; Prednisone; Thymidine; Tritium; Vincristine | 1973 |
[Triggering of Go in cycle cells under the effect of cytotoxic substances].
Topics: Cell Division; Cytarabine; Doxorubicin; Humans; Leukemia; Male; Methotrexate; Middle Aged; Vincristine | 1973 |
[Treatment of acute leukemia with 2,2'-anhydro-1-beta-D-arabinofuranosylcytosine hydrochloride (cyclocytidine) (author's transl)].
Topics: Acute Disease; Adolescent; Adult; Anhydrides; Antineoplastic Agents; Child, Preschool; Cytarabine; Drug Evaluation; Female; Humans; Leukemia; Male; Middle Aged | 1973 |
Effect of cytostatic drugs on the kinetics of leukemic blast cells in man.
Topics: Antineoplastic Agents; Asparaginase; Bone Marrow; Bone Marrow Cells; Cell Division; Cytarabine; Daunorubicin; DNA, Neoplasm; Drug Therapy, Combination; Humans; Leukemia; Methotrexate; Mitosis; Prednisone; Spectrophotometry; Thymidine; Time Factors; Vincristine | 1974 |
Proceedings: Triple chemotherapy in acute non-lymphocytic leukaemia.
Topics: Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia; Vincristine | 1974 |
[Modern treatment of adult acute non-lymphocytic leukemia].
Topics: Acute Disease; Adult; Antineoplastic Agents; Cytarabine; Humans; Leukemia; Methotrexate; Prednisone; Vincristine | 1974 |
Local experience in the treatment of acute non-lymphoblastic leukaemia.
Topics: Acute Disease; Adult; Antineoplastic Agents; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia; Mercaptopurine; Middle Aged; Prednisone; Remission, Spontaneous; Retrospective Studies; Vincristine | 1974 |
Management of acute non-lymphocytic leukaemia.
Topics: Acute Disease; Age Factors; Cytarabine; Daunorubicin; Female; Humans; Injections; Leukemia; Male; Methods; Prognosis; Remission, Spontaneous; Time Factors; Vincristine | 1974 |
Studies on cellular proliferation in human leukemia. VII. Cytokinetic behavior of neoplastic cells in a patient with reticulum cell sarcoma in a leukemic phase.
Topics: Adult; Autoradiography; Biopsy; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Cell Differentiation; Culture Techniques; Cytarabine; DNA, Neoplasm; Female; Histocytochemistry; Humans; Leukemia; Leukocytes; Lymphoma, Non-Hodgkin; Mitosis; Phagocytosis; Thymidine; Tritium | 1971 |
Cytosine arabinoside in a case of reticulum cell leukemia.
Topics: Adolescent; Cytarabine; Female; Humans; Leukemia; Lymphoid Tissue; Remission, Spontaneous | 1972 |
[Polychemotherapy of acute leukemias in children and adolescents].
Topics: Acute Disease; Adolescent; Age Factors; Antineoplastic Agents; Asparaginase; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Glucocorticoids; Humans; Leukemia; Mercaptopurine; Methotrexate; Prednisone; Vincristine | 1972 |
A cellular approach to the chemotherapy of spontaneous leukemia of AKR mice.
Topics: Animals; Asparaginase; Biological Assay; Cell Survival; Cyclophosphamide; Cytarabine; Female; Hydrocortisone; Leukemia; Lymphatic Metastasis; Mice; Neoplasm Transplantation; Nitrosourea Compounds; Prednisolone; Splenomegaly; Thymectomy; Thymus Gland; Vinblastine; Vincristine | 1972 |
Action of 1- -D-arabinofuranosylcytosine on mammalian tumor cells. 2. Inhibition of mammalian and oncogenic viral polymerases.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Cytarabine; DNA Nucleotidyltransferases; Leukemia; Liver; Lymphoma; Mice; Oncogenic Viruses; Rauscher Virus | 1972 |
Management of CNS leukemia in childhood. An outline of current concepts.
Topics: Central Nervous System Diseases; Child; Child, Preschool; Cytarabine; Humans; Leukemia; Meninges; Methotrexate; Pyrimethamine | 1972 |
Cyclophosphamide (NSC-26271), vincristine (NSC-67574), cytosine arabinoside (NSC-63878), and prednisone (NSC-10023) (COAP) combination chemotherapy for acute leukemia in adults.
Topics: Adolescent; Adult; Age Factors; Aged; Blood Platelets; Chemical and Drug Induced Liver Injury; Cyclophosphamide; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged; Prednisone; Remission, Spontaneous; Vincristine | 1972 |
A micro-system for screening anti-leukemic drugs utilizing human whole blood.
Topics: Adult; Aged; Cytarabine; DNA; Evaluation Studies as Topic; Female; Humans; Infant; Leukemia; Leukocytes; Male; Mercaptopurine; Middle Aged; Quinacrine; RNA; Thymidine; Tritium; Uridine | 1971 |
[In vitro proliferation of leukemic blast cells and response to daunorubidomycin-cytosine arabinoside].
Topics: Autoradiography; Bone Marrow; Bone Marrow Cells; Cell Count; Cytarabine; Daunorubicin; Humans; Leukemia; Muramidase; Thymidine; Tritium | 1971 |
[Significance of cellular kinetics in relation to chemotherapy of human leukemias].
Topics: Adult; Aged; Alkylating Agents; Antibiotics, Antineoplastic; Antineoplastic Agents; Blood Platelets; Cell Division; Cell Movement; Cytarabine; Female; Humans; Immunosuppressive Agents; Leukemia; Leukocytes; Male; Middle Aged; Neoplastic Cells, Circulating; Nitrogen Mustard Compounds; Nitroso Compounds; Urea | 1971 |
[Kinetic aspects of the chemotherapy of acute leukemia in children].
Topics: Acute Disease; Antibiotics, Antineoplastic; Antineoplastic Agents; Child; Cyclophosphamide; Cytarabine; Humans; Leukemia; Mercaptopurine; Methotrexate; Prednisolone; Vinblastine; Vincristine | 1971 |
[Therapy of leukemic meningiosis. I].
Topics: Acute Disease; Adolescent; Child; Child, Preschool; Cytarabine; Electroencephalography; Humans; Infant; Injections, Spinal; Leukemia; Meninges; Methotrexate; Neoplasm Metastasis; Neurologic Manifestations; Recurrence | 1971 |
Prediction of in vivo cytotoxicity of chemotherapeutic agents by their effect on malignant leukocytes in vitro.
Topics: Blood Cell Count; Cytarabine; DNA; Humans; In Vitro Techniques; Injections, Intravenous; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Mercaptopurine; Multiple Myeloma; Prednisone; RNA; Tritium; Uridine; Vincristine | 1967 |
[Chemotherapy of acute leukemia].
Topics: Acute Disease; Adrenal Cortex Hormones; Adult; Antineoplastic Agents; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Thrombocythemia, Essential; Vincristine | 1967 |
Summary: recent advances in the treatment of acute leukemia and Burkitt's tumor.
Topics: Antineoplastic Agents; Asparaginase; Burkitt Lymphoma; Cyclophosphamide; Cytarabine; Daunorubicin; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Nitroso Compounds; Prednisone; Urea; Vincristine | 1967 |
Biochemical studies with 1 beta-D-arabinofuranosylcytosine in human leukemic leukocytes and normal bone marrow cells.
Topics: Adolescent; Adult; Aged; Animals; Bone Marrow; Bone Marrow Cells; Child, Preschool; Cytarabine; DNA Replication; DNA, Neoplasm; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukocyte Count; Leukocytes; Male; Middle Aged; Neoplasm Proteins; Nucleosides; RNA, Neoplasm; Sarcoma, Experimental; Tritium | 1968 |
Drugs in the treatment of leukemia.
Topics: Asparaginase; Busulfan; Chlorambucil; Cyclophosphamide; Cytarabine; Humans; Hydroxyurea; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Pipobroman; Prednisolone; Vincristine | 1968 |
Uptake and phosphorylation of cytosine arabinoside by normal and leukemic human blood cells in vitro.
Topics: Blood Platelets; Cell Membrane Permeability; Cytarabine; Cytosine Nucleotides; Erythrocytes; Humans; In Vitro Techniques; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphocytes; Oxidative Phosphorylation; Temperature; Tritium | 1969 |
Drug effect in acute leukemia.
Topics: Adolescent; Bone Marrow; Bone Marrow Cells; Child; Child, Preschool; Cytarabine; DNA, Neoplasm; Humans; Hydrocortisone; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mitosis; Prednisone; Thymidine; Tritium; Vincristine | 1969 |
Hypersplenism due to disseminated candidiasis in a patient with acute leukemia.
Topics: Acute Disease; Adult; Amphotericin B; Blood Cell Count; Blood Platelets; Candida; Candidiasis; Cytarabine; Feces; Fever; Humans; Hypersplenism; Leukemia; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Nose; Pharynx; Prednisone; Skin; Spleen | 1969 |
Prolonged infusion of arabinosyl cytosine in childhood leukemia.
Topics: Adolescent; Body Surface Area; Bone Marrow; Child; Child, Preschool; Cytarabine; Female; Humans; Infant; Injections, Intravenous; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukopenia; Male; Time Factors | 1970 |
Intrathecal arabinosyl cytosine in meningeal leukemia.
Topics: Adolescent; Brain Neoplasms; Cerebrospinal Fluid; Child; Child, Preschool; Cytarabine; Female; Humans; Injections, Spinal; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Meninges; Time Factors | 1970 |
Experience with the use of cytosine arabinoside in adult acute leukaemia.
Topics: Acute Disease; Adolescent; Adult; Cyclophosphamide; Cytarabine; Female; Humans; Injections, Intravenous; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged | 1970 |
Preliminary evaluation of cyclophosphamide (NSC-26271) and cytosine arabinoside (NSC-63878) in acute leukemia of children.
Topics: Adolescent; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Female; Humans; Infant; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male | 1969 |
Leukemia and lymphoma.
Topics: Antineoplastic Agents; BCG Vaccine; Burkitt Lymphoma; Busulfan; Chlorambucil; Cyclophosphamide; Cytarabine; Hodgkin Disease; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma; Lymphoma, Non-Hodgkin; Prednisone; Vincristine | 1970 |
[Treatment of acute leukemia].
Topics: Acute Disease; Adolescent; Adult; Antibiotics, Antineoplastic; Antilymphocyte Serum; Antineoplastic Agents; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Drug Synergism; Female; Humans; Immunotherapy; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Prednisone; Vincristine | 1970 |
L-asparaginase: clinical, biochemical, pharmacological, and immunological studies.
Topics: Adolescent; Adult; Antibody Formation; Antineoplastic Agents; Asparaginase; Asparagine; Bone Marrow Examination; Child; Child, Preschool; Cytarabine; Drug Hypersensitivity; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisone; Remission, Spontaneous | 1971 |
[Round table conference--present status and the future of treatment of leukemia].
Topics: Acute Disease; Asparaginase; Cytarabine; Daunorubicin; Glutaminase; Humans; Leukemia; Leukemia, Myeloid; Vinblastine; Vincristine | 1971 |
Cytarabine.
Topics: Acute Disease; Amino Sugars; Anemia; Antibiotics, Antineoplastic; Antineoplastic Agents; Blood Cell Count; Cyclophosphamide; Cytarabine; Glycosides; Humans; Injections, Intravenous; Injections, Subcutaneous; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukopenia; Lymphoma; Prednisone; Remission, Spontaneous; Thioguanine; Thrombocytopenia; Vincristine | 1971 |
Experiences with cytosine arabinoside in childhood leukaemia and lymphoma.
Topics: Acute Disease; Adolescent; Central Nervous System Diseases; Child; Child, Preschool; Cytarabine; Female; Humans; Infant; Injections, Intravenous; Injections, Spinal; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Neoplasm Regression, Spontaneous | 1971 |
Cytidine deaminase and the development of resistance to arabinosyl cytosine.
Topics: Adult; Aminohydrolases; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Cyclophosphamide; Cytarabine; Cytidine; Drug Resistance; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Spectrum Analysis; Time Factors | 1971 |
Observations on the plasma amino acids of patients with acute leukemia.
Topics: Acute Disease; Alanine; Amino Acids; Asparaginase; Cytarabine; Glucocorticoids; Glutamine; Histidine; Humans; Indicators and Reagents; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Methionine; Methotrexate; Nitrogen; Proline; Threonine; Vincristine | 1971 |
Hyperleukocytosis before the beginning of treatment in acute leukaemia in children and its subsequent repetition at the onset of relapses.
Topics: Acute Disease; Antibiotics, Antineoplastic; Bone Marrow Examination; Child; Cytarabine; Humans; Leukemia; Leukemia, Lymphoid; Leukocytosis; Mercaptopurine; Methotrexate; Prednisone; Prognosis; Recurrence; Vincristine | 1970 |
[Therapy of acute leukemia. 4. Remission induction and remission maintenance therapy].
Topics: Acute Disease; Adolescent; Adrenal Cortex Hormones; Adult; Age Factors; Aged; Asparaginase; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Middle Aged; Remission, Spontaneous; Vincristine | 1971 |
[Experiences in the treatment of immature cell leukemias with cytosine arabinoside and daunorubidomycin].
Topics: Adolescent; Adult; Aged; Agranulocytosis; Allopurinol; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Blood Transfusion; Cytarabine; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Middle Aged; Muramidase; Nausea; Prednisolone; Thrombocytopenia; Vincristine | 1971 |
Selecting drug regimens in human leukemia.
Topics: Antineoplastic Agents; Cell Membrane Permeability; Child; Cyclophosphamide; Cytarabine; Drug Combinations; Drug Resistance; Follow-Up Studies; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Nucleotides; Prednisone; Prognosis; Vincristine | 1971 |
DNA synthesis in leukemic cells under the action of cytotoxic agents in vitro and in vivo.
Topics: Adult; Aged; Antineoplastic Agents; Cells, Cultured; Cytarabine; Daunorubicin; DNA, Neoplasm; Female; Glucocorticoids; Humans; In Vitro Techniques; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocytes; Male; Methotrexate; Middle Aged; Prognosis; Thymine Nucleotides; Tritium | 1971 |
[Induction and interval treatment of leukemias in children and juveniles].
Topics: Adolescent; Antineoplastic Agents; Asparaginase; Central Nervous System Diseases; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Injections, Intravenous; Leukemia; Male; Meninges; Mercaptopurine; Methotrexate; Prednisone; Vincristine | 1969 |
[Spinal administration of cytosine arabinose in a case of refractory meningocerebral leukemia].
Topics: Child; Cytarabine; Humans; Leukemia; Male | 1969 |
[Progress in the treatment of acute leukemias].
Topics: Antineoplastic Agents; Asparaginase; Cytarabine; Daunorubicin; Humans; Leukemia; Prednisone; Vincristine | 1969 |
[Biochemical basis of the treatment of leukemia with cytosine-arabinoside].
Topics: Cytarabine; DNA, Neoplasm; Humans; Leukemia; Leukocytes; Prednisolone; RNA, Neoplasm; Thymidine Kinase | 1970 |
[Acute leukemia].
Topics: Acute Disease; Asparaginase; Cytarabine; Daunorubicin; Humans; Leukemia | 1970 |
Severe generalized primary herpes treated with cytarabine.
Topics: Adult; Cytarabine; Encephalitis; Herpes Simplex; Humans; Leukemia; Male; Stomatitis | 1970 |
Combinations, schedules, and new agents for the chemotherapy of acute leukemia.
Topics: Acute Disease; Adult; Antineoplastic Agents; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Humans; Leukemia; Leukemia, Lymphoid; Mercaptopurine; Methotrexate; Nitroso Compounds; Prednisone; Urea; Vincristine | 1970 |
[Treatment of leukemia with cytosine arabinoside--on the intensification of remission].
Topics: Adolescent; Adult; Aged; Child; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged; Nucleosides | 1970 |
[A common therapy program of leukemia for several hospitals].
Topics: Acute Disease; Adult; Asparaginase; Blood Platelets; Blood Transfusion; Cyclophosphamide; Cytarabine; Humans; Leukemia; Leukocytes; Mercaptopurine; Prednisolone; Sweden | 1970 |
1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU; NSC-409962) given concomitantly with cytosine arabinoside (NSC-63878) in the treatment of cancer.
Topics: Adult; Aged; Antineoplastic Agents; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged; Neoplasm Metastasis; Neoplasms; Nitroso Compounds; Nitrosourea Compounds; Urea | 1970 |
[New cytostatics in the treatment of acute leukemias in childhood].
Topics: Acute Disease; Aminopterin; Antineoplastic Agents; Asparaginase; Child; Cortisone; Cyclophosphamide; Cytarabine; Daunorubicin; Evaluation Studies as Topic; Humans; Leukemia; Mercaptopurine; Methotrexate; Prednisone; Vincristine | 1970 |
Methotrexate and cytosine arabinoside modulation of thymidylate synthetase activity in CCRF-CEM cells.
Topics: Cell Line; Culture Techniques; Cytarabine; Dialysis; Humans; Leukemia; Leukocytes; Methotrexate; Methyltransferases; Stimulation, Chemical; Time Factors; Transferases; Uracil Nucleotides | 1971 |
Cytosine arabinoside. Results of a cooperative study in acute childhood leukemia.
Topics: Acute Disease; Adolescent; Blood Cell Count; Blood Platelets; Bone Marrow; Bone Marrow Cells; Child; Child, Preschool; Cytarabine; Female; Follow-Up Studies; Humans; Injections, Intravenous; Leukemia; Leukocyte Count; Male | 1968 |
Therapy for acute leukemia in adults with cytosine arabinoside (NSC-63878), vincristine (NSC-67574), and prednisone (NSC-10023).
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Agents; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged; Prednisone; Vincristine | 1968 |
Cytosine arabinoside (NSC-63878) therapy for acute leukemia in adults.
Topics: Adolescent; Adult; Aged; Cytarabine; Female; Humans; Injections, Intravenous; Leukemia; Male; Middle Aged | 1969 |
Cytosine arabinoside (NSC-63878) given subcutaneously to patients with cancer.
Topics: Adolescent; Adult; Aged; Blood Cell Count; Child; Cytarabine; Female; Humans; Injections, Subcutaneous; Leukemia; Lymphoma; Male; Middle Aged | 1969 |
The treatment of acute leukaemia with cytosine arabinoside: biochemical and clinical findings.
Topics: Cytarabine; Cytosine Nucleotides; Leukemia; Nucleotides; Prednisolone; Prednisone; Thymidine Kinase | 1969 |
[A new agent active in the treatment of acute leukemia: cytosine arabinoside].
Topics: Adolescent; Adult; Child; Child, Preschool; Cytarabine; Humans; Leukemia | 1966 |
Cytosine arabinoside (NSC-63878) in acute leukemia in children.
Topics: Adolescent; Child; Child, Preschool; Cytarabine; Female; Humans; In Vitro Techniques; Leukemia; Male | 1966 |