cytarabine and Leukemia L5178

cytarabine has been researched along with Leukemia L5178 in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199014 (66.67)18.7374
1990's4 (19.05)18.2507
2000's1 (4.76)29.6817
2010's2 (9.52)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dias, CB; Hansch, C; Khwaja, TA; Pentecost, S; Selassie, CD1
Cariou, O; Guizon, I; Laroche-Prigent, N; Ledieu, S; Paillard, F; Thybaud, V1
Hynes, L1
Aardema, MJ; Lorenzon, G; Lorge, E; Marzin, D; Oliver, J; Thybaud, V; Wakata, A1
Allaudeen, HS; Chang, PK; Chu, MY; Itoh, YH; Sartorelli, AC1
Arlett, CF; Cole, J; Green, MH; Lowe, J; Muriel, W1
Capizzi, RL; Morgenstern, B; Schwartz, SA1
Arlett, CF; Burns, VW; Hill, R; Lehmann, AR; Rogers, AM1
Calabresi, P; Chu, MY; Srivastava, SP; Steim, JM; Tibbetts, LM; Turcotte, JG1
Caspary, WJ; Hines, KC; Spencer, DL1
Côte-Rozanes, C; Czyzewska-Szafran, H; Jastrzebski, Z; Remiszewska, M1
Kornacka, L; Malec, J; Sawecka, J1
Capizzi, RL; Kucera, GL1
Capizzi, RL; Wang, LM; White, JC1
Capizzi, RL; Chandrasekaran, B; Dimling, J; Kute, TE; Morgan, T1
Capizzi, RL; Daniel, LW; King, L; Waite, M; Yang, JL1
Johanson, KJ; Szumiel, I; Wlodek, D1
Capizzi, RL; Cooper, MR; Jackson, DV; Muss, HB; Powell, BL; Rathmell, JP; Richards, F; Stuart, JJ; White, DR; White, JC1
Capizzi, RL; Rathmell, JP; White, JC1
Capizzi, RL; Cheng, E; Cheng, YC; Kute, T; Rathmell, JP; White, JC; Yang, JL1
Capizzi, RL; Cheng, EH; Cheng, YC; Kute, T; Yang, JL1

Reviews

1 review(s) available for cytarabine and Leukemia L5178

ArticleYear
Dose-related pharmacologic effects of high-dose ara-C and its self-potentiation.
    Seminars in oncology, 1985, Volume: 12, Issue:2 Suppl 3

    Topics: Aging; Animals; Arabinofuranosyluracil; Biological Transport; Bone Marrow; Cell Line; Cell Membrane; Clinical Trials as Topic; Cytarabine; DNA; Dose-Response Relationship, Drug; Drug Resistance; Half-Life; Humans; Interphase; Leukemia; Leukemia L5178; Time Factors

1985

Trials

1 trial(s) available for cytarabine and Leukemia L5178

ArticleYear
Dose-related pharmacologic effects of high-dose ara-C and its self-potentiation.
    Seminars in oncology, 1985, Volume: 12, Issue:2 Suppl 3

    Topics: Aging; Animals; Arabinofuranosyluracil; Biological Transport; Bone Marrow; Cell Line; Cell Membrane; Clinical Trials as Topic; Cytarabine; DNA; Dose-Response Relationship, Drug; Drug Resistance; Half-Life; Humans; Interphase; Leukemia; Leukemia L5178; Time Factors

1985

Other Studies

20 other study(ies) available for cytarabine and Leukemia L5178

ArticleYear
Comparative structure-activity relationships of antifolate triazines inhibiting murine tumor cells sensitive and resistant to methotrexate.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:3

    Topics: Animals; Chemical Phenomena; Chemistry, Physical; Chickens; Drug Resistance; Folic Acid Antagonists; Humans; Leukemia L5178; Leukemia, Experimental; Mathematics; Methotrexate; Mice; Structure-Activity Relationship; Triazines

1984
Cytosine arabinoside, vinblastine, 5-fluorouracil and 2-aminoanthracene testing in the in vitro micronucleus assay with L5178Y mouse lymphoma cells at Sanofi Aventis, with different cytotoxicity measurements, in support of the draft OECD Test Guideline on
    Mutation research, 2010, Oct-29, Volume: 702, Issue:2

    Topics: Animals; Anthracenes; Cell Count; Cell Line, Tumor; Cytarabine; Fluorouracil; France; Guidelines as Topic; Leukemia L5178; Mice; Micronucleus Tests; Mutagens; Vinblastine

2010
Comparison of different methods for an accurate assessment of cytotoxicity in the in vitro micronucleus test without cytokinesis block.
    Mutation research, 2010, Oct-29, Volume: 702, Issue:2

    Topics: Animals; Benzopyrenes; Cell Count; Cell Line, Tumor; Cell Proliferation; Cytarabine; Cytokinesis; Diethylstilbestrol; Etoposide; Guidelines as Topic; Leukemia L5178; Mice; Micronucleus Tests; Mutagens

2010
SFTG international collaborative study on in vitro micronucleus test I. General conditions and overall conclusions of the study.
    Mutation research, 2006, Aug-04, Volume: 607, Issue:1

    Topics: Aneugens; Animals; Bleomycin; Cell Line; CHO Cells; Clofibrate; Colchicine; Cricetinae; Cytarabine; Cytochalasin B; Diethylstilbestrol; Fluorouracil; Griseofulvin; Humans; In Vitro Techniques; International Cooperation; Leukemia L5178; Lymphocytes; Mannitol; Mice; Micronucleus Tests; Mitomycin; Mutagens; Thiabendazole

2006
Evaluation of 2,2'-anhydro-1-(3'-Ok-acetyl-beta-D-arabinofuranosyl)-5-iodocytosine hydrochloride and related compounds as antineoplastic and antiviral agents.
    Chemico-biological interactions, 1981, Volume: 33, Issue:2-3

    Topics: Animals; Antineoplastic Agents; Antiviral Agents; Cells, Cultured; Cytarabine; Female; Leukemia L1210; Leukemia L5178; Leukemia P388; Macromolecular Substances; Mice; Nucleic Acid Synthesis Inhibitors; Simplexvirus

1981
A comparison of the agar cloning and microtitration techniques for assaying cell survival and mutation frequency in L5178Y mouse lymphoma cells.
    Mutation research, 1983, Volume: 111, Issue:3

    Topics: Agar; Animals; Cell Survival; Clone Cells; Culture Media; Culture Techniques; Cytarabine; Leukemia L5178; Leukemia, Experimental; Mice; Mutation; Thioguanine

1983
Schedule-dependent synergy and antagonism between high-dose 1-beta-D-arabinofuranosylcytosine and asparaginase in the L5178Y murine leukemia.
    Cancer research, 1982, Volume: 42, Issue:6

    Topics: Animals; Asparaginase; Biological Transport; Cell Division; Cell Survival; Cytarabine; Drug Administration Schedule; Drug Antagonism; Drug Synergism; Drug Therapy, Combination; Kinetics; Leukemia L5178; Leukemia, Experimental; Mice; Mitotic Index

1982
The induction and characterization of mouse lymphoma L5178Y cell lines resistant to 1-beta-d-arabinofuranosylcytosine.
    Mutation research, 1980, Volume: 69, Issue:1

    Topics: 2-Acetylaminofluorene; Animals; Cell Line; Cytarabine; Drug Resistance; Ethidium; Ethyl Methanesulfonate; Leukemia L5178; Leukemia, Experimental; Mice; Mutagens; Mutation; Thymidine

1980
Cytotoxic liponucleotide analogs. II. Antitumor activity of CDP-diacylglycerol analogs containing the cytosine arabinoside moiety.
    Biochimica et biophysica acta, 1980, Sep-08, Volume: 619, Issue:3

    Topics: Animals; Antineoplastic Agents; Cell Line; Cytarabine; Cytidine Diphosphate Diglycerides; Humans; Leukemia L5178; Leukemia P388; Mice; Neoplasms, Experimental; Nucleoside Diphosphate Sugars

1980
An in situ protocol for measuring the expression of chemically-induced mutations in mammalian cells.
    Mutation research, 1994, Volume: 312, Issue:2

    Topics: Animals; Azacitidine; Cell Division; Cell Separation; Cytarabine; Dose-Response Relationship, Drug; Drug Resistance; Leukemia L5178; Mice; Mutagenesis, Site-Directed; Mutagenicity Tests; Mutagens; Phenotype; Reproducibility of Results; Thymidine Kinase; Trifluridine; Tumor Cells, Cultured

1994
Intracellular accumulation of cytosine arabinoside in murine normal and neoplastic lymphocytes following their exposure to sodium 2-mercaptoethanesulphonate.
    Leukemia research, 1993, Volume: 17, Issue:9

    Topics: Animals; Cells, Cultured; Cytarabine; Dose-Response Relationship, Drug; Female; Leukemia L5178; Lymphocyte Activation; Lymphocytes; Lymphoma, Non-Hodgkin; Male; Mesna; Mice; Phytohemagglutinins; Tumor Cells, Cultured

1993
Differential cell-cycle-dependent inhibition of DNA synthesis by hydroxyurea and cytosine arabinoside in cultured L5178Y mouse lymphoma cells.
    Archivum immunologiae et therapiae experimentalis, 1979, Volume: 27, Issue:4

    Topics: Animals; Cell Cycle; Cell Line; Cytarabine; DNA, Neoplasm; Hydroxyurea; Leukemia L5178; Leukemia, Experimental; Mice; Mitosis

1979
1-beta-D-arabinofuranosylcytosine-diphosphate-choline is formed by the reversal of cholinephosphotransferase and not via cytidylyltransferase.
    Cancer research, 1992, Jul-15, Volume: 52, Issue:14

    Topics: Animals; Choline-Phosphate Cytidylyltransferase; Cytarabine; Cytidine Diphosphate Choline; Diacylglycerol Cholinephosphotransferase; Leukemia L5178; Nucleotidyltransferases; Vidarabine Phosphate

1992
The effect of ara-C-induced inhibition of DNA synthesis on its cellular pharmacology.
    Cancer chemotherapy and pharmacology, 1990, Volume: 25, Issue:6

    Topics: Animals; Arabinofuranosylcytosine Triphosphate; Cytarabine; Depression, Chemical; DNA-Directed DNA Polymerase; DNA, Neoplasm; Leukemia L5178; Mice; Ribonucleoside Diphosphate Reductase; Thymidine; Thymidine Kinase; Thymine Nucleotides; Tumor Cells, Cultured; Tumor Stem Cell Assay

1990
Modulation of the metabolism and pharmacokinetics of 1-beta-D-arabinofuranosylcytosine by 1-beta-D-arabinofuranosyluracil in leukemic mice.
    Cancer research, 1989, Jun-15, Volume: 49, Issue:12

    Topics: Animals; Arabinofuranosyluracil; Cytarabine; Cytidine Deaminase; Kidney; Kinetics; Leukemia L5178; Leukemia, Experimental; Liver; Male; Mice; Mice, Inbred Strains; Uridine

1989
Effect of cytarabine upon metabolism of phospholipids in leukemia L5178Y cells.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1986, Volume: 7, Issue:4

    Topics: Animals; Cell Line; Cytarabine; Leukemia L5178; Leukemia, Experimental; Mice; Phospholipids

1986
Impaired repair of UVC-induced DNA damage in L5178Y-R cells: DNA unwinding studies with the use of 1-beta-D-arabinofuranosyl cytosine.
    Photochemistry and photobiology, 1988, Volume: 48, Issue:2

    Topics: Animals; Cytarabine; DNA Damage; DNA Repair; DNA Replication; DNA, Neoplasm; Leukemia L5178; Mice; Ultraviolet Rays

1988
Dose-related pharmacologic effects of high dose ara-C and its use in combination with asparaginase for the treatment of patients with acute non-lymphocytic leukemia.
    Scandinavian journal of haematology. Supplementum, 1986, Volume: 44

    Topics: Acute Disease; Animals; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Carcinoma, Ehrlich Tumor; Cell Line; Cytarabine; Dose-Response Relationship, Drug; Drug Resistance; Humans; Leukemia; Leukemia L5178; Mice

1986
Membrane transport influences the rate of accumulation of cytosine arabinoside in human leukemia cells.
    The Journal of clinical investigation, 1987, Volume: 79, Issue:2

    Topics: Acute Disease; Adult; Animals; Biological Transport; Carcinoma, Ehrlich Tumor; Cell Line; Cell Membrane; Cytarabine; Humans; Kinetics; Leukemia; Leukemia L5178; Leukemia P388; Mathematics; Mice

1987
Effect of uracil arabinoside on metabolism and cytotoxicity of cytosine arabinoside in L5178Y murine leukemia.
    The Journal of clinical investigation, 1985, Volume: 75, Issue:1

    Topics: Animals; Arabinofuranosyluracil; Cytarabine; Cytotoxicity, Immunologic; Drug Interactions; Humans; Kinetics; Leukemia L5178; Leukemia, Experimental; Tumor Stem Cell Assay; Uridine

1985