cytarabine has been researched along with Experimental Neoplasms in 188 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 169 (89.89) | 18.7374 |
1990's | 9 (4.79) | 18.2507 |
2000's | 5 (2.66) | 29.6817 |
2010's | 3 (1.60) | 24.3611 |
2020's | 2 (1.06) | 2.80 |
Authors | Studies |
---|---|
Bauer, CH; Grünholz, H; Reutter, W; Vischer, P | 1 |
Reutter, W; Vischer, P | 1 |
An, SH; Bernacki, RJ; Bobek, M; De Clercq, E; Skrincosky, D | 1 |
Kim, SH; Rosowsky, A; Ross, J; Wick, MM | 1 |
Hong, CI; MacCoss, M; Matsushita, T; Ross, RJ; Ryu, EK; West, CR | 1 |
Chen, Y; Dong, R; Duan, C; Huang, J; Jiang, F; Li, H; Li, S; Liu, C; Lu, T; Tang, W; Wang, X; Xu, J; Zhang, T; Zhang, Y; Zhu, G; Zhu, Y | 1 |
Cheng, X; Fu, C; Huang, F; Jia, X; Meng, Y; Shao, G; Wang, L; Wang, T; Wang, X; Wu, H; Yang, T | 1 |
Chen, CD; Jiang, H; Li, X; Liu, M; Zhang, Y; Zheng, L | 1 |
Han, AR; Kim, HJ; Kim, SH; Lee, JY; Min, WS; Park, G | 1 |
Amano, S; Gao, Y; Gu, C; Koizumi, S; Namba, H; Tokuyama, T; Yokota, N | 1 |
Bagg, A; Carroll, M; Scialla, TJ; Simpson, SE; Xu, Q | 1 |
BOSTWICK, L; EVANS, JS; MENGEL, GD | 1 |
EVANS, JS; MENGEL, GD | 1 |
BOSTWICK, L; EVANS, JS; MENGEL, GD; MUSSER, EA | 1 |
Chen, J; Chen, SJ; Chen, Z; Gao, L; Gu, LJ; Kang, H; Liu, P; Shen, ZX; Wang, L; Wang, ZY; Weng, XQ; Xie, J; Yan, M; Zhang, DE; Zhang, FX; Zhou, GB | 1 |
Cheang, PT; Chen, CS; Fred Wong, WS; Han, JH; Khan, M; Shen, J; Stephen Wong, CH; Tai, YC; Xie, Z; Zhou, J | 1 |
Buskirk, HH; Lummis, WL; Smith, CG | 1 |
Skipper, HE | 2 |
Ford, CH; Howell, A; Newman, CE; Wilson, AP | 1 |
Imamishi, J; Tanaka, A | 1 |
Bothwell, MA; Gunning, PW; Landreth, GE; Shooter, EM | 1 |
Tsukagoshi, S | 1 |
Hori, K; Naganuma, K; Sakurai, Y; Tsukagoshi, S; Tsuruo, T | 1 |
Floersheim, GL | 1 |
Fujita, M; Hayata, S; Taguchi, T | 1 |
Faanes, RB; Merluzzi, VJ; Susskind, BM | 1 |
Marbrook, J; Reid, ML | 1 |
Lauzon, GJ; Paterson, AR; Yang, S | 1 |
Barzi, A; Bonmassar, E; Frati, L; Migliorati, G | 1 |
Au, JL; Danhauser, L; Luccioni, C; Rustum, YM | 1 |
Maruyama, Y; Young, JA | 1 |
Richardson, VJ; Ryman, BE | 1 |
Curt, GA; Richardson, VJ; Ryman, BE | 1 |
Brockman, RW; Corbett, TH; Griswold, DP; Laster, WR; Schabel, FM; Skipper, HE; Trader, MW | 1 |
Burke, PJ; Karp, JE; Saylor, PL; Vaughan, WP | 1 |
Barlogie, B; Bergerat, JP; Corry, P; Drewinko, B; Ho, DH | 1 |
Allen, TM; Gyorffy, E; Mausolf, S; McAllister, L | 1 |
Reiter, H | 1 |
Danhauser, LL; Rustum, YM | 1 |
Monaghan, P; Peckham, MJ; Selby, PJ; Sloane, J; Thomas, JM | 1 |
O'Neill, GJ; Stebbing, N | 1 |
Corbett, TH; Griswold, DP; Simpson-Herren, L | 1 |
O'Neill, GJ | 1 |
Mazrimas, JA; Pallavicini, MG | 1 |
Calabresi, P; Chu, MY; Srivastava, SP; Steim, JM; Tibbetts, LM; Turcotte, JG | 1 |
Feuers, RJ; McClellan, JL; Scheving, LA; Scheving, LE | 1 |
De Traversay, J; Jean, Y; Lemieux, P | 1 |
Nagase, S; Saito, T; Sato, S; Watanabe, S | 1 |
Endo, Y; Sasaki, T; Zhang, M | 1 |
Hanaoka, K; Hisaoka, M; Ikeda, T; Iwabuchi, H; Kaneko, M; Kobayashi, T; Kurakata, S; Matsuda, A; Mitsuhashi, Y; Miura, S; Nakagawa, A; Nomura, T; Sasaki, T; Shibayama, T; Suzuki, M; Tanaka, K; Tanzawa, F; Tomida, A; Tsuruo, T; Wataya, Y | 1 |
Duesberg, P; Hehlmann, R; Kraemer, A; Li, R; Rasnick, D; Rausch, C; Willer, A; Yerganian, G | 1 |
Asai, T; Kondo, M; Kuromi, K; Matsuda, A; Ogino, K; Oku, N; Shimizu, K; Shuto, S; Taki, T; Watanabe, K | 1 |
Kreis, W; Meyers, MB | 2 |
Borsos, T; Ohanian, SH; Segerling, M | 2 |
Kagawa, S; Yokota, T | 1 |
Abe, I; Sato, S | 1 |
Basler, GA; Shapiro, WR | 1 |
Igarashi, T; Kishimoto, T; Okada, M; Yamamura, Y | 1 |
Murphy, GP; Sufrin, G | 1 |
Grieder, A; Maurer, R; Stähelin, H | 1 |
Chen, FP; El Dareer, SM; Hill, DL; Mellett, LB; Tillery, K; White, VM | 1 |
Barranco, SC; Gee, EL; Haenelt, BR | 1 |
Iwaguchi, T; Kitagawa, H | 1 |
Fodstad, O | 1 |
Schabel, FM | 1 |
Azizkhan, JC; Goode, D; Speeg, KV; Stromberg, K | 1 |
Furner, RL; Mellett, LB | 1 |
Brockman, RW; Nelson, JA; Rose, LM; Schabel, FM; Shaddix, SC; Williams, M | 1 |
Tevethia, MJ; Tevethia, SS | 1 |
Roubal, J | 1 |
Carlevarini, LA; Krakoff, IH; Kreis, W; Meyers, MB; Woodcock, TM | 1 |
Rustum, YM | 2 |
Marz, R; Plagemann, PG; Wohlhueter, RM | 1 |
Konings, AW; Trieling, WB | 1 |
Dumenil, D; Fache, MP; Frindel, E; Guigon, M | 1 |
Grindey, GB; Mihich, E | 1 |
Belousova, AK | 1 |
Cooper, IA; Fox, RM; Woodcock, DM | 1 |
Krieg, L; Mattern, J; Volm, M; Wayss, K | 1 |
Hession, C; Kreis, W; Scully, K; Soricelli, A | 1 |
Higby, DJ; Rustum, YM | 1 |
Bonmassar, E; Fioretti, MC; Giampietri, A; Goldin, A; Puccetti, P; Riccardi, C | 1 |
Hellman, S; Little, JB; Nove, JJ; Piro, AJ; Weichselbaum, RR | 1 |
Bonmassar, E; Giovanella, B; Goldin, A; Merletti, PR | 1 |
Finch, LR; Harris, AW; Reynolds, EC | 1 |
Shimkin, MB; Stoner, GD; Theiss, JC | 1 |
Fox, JJ; Hollenberg, DH; Watanabe, KA | 1 |
Chinnadurai, G; Gilead, Z; Green, M; Jeng, YH | 1 |
Baker, MS; Benedict, WF; Bertram, JS; Jones, PA | 1 |
Nicolini, C | 1 |
Kreis, W | 2 |
Murphy, P; Sufrin, G | 1 |
Bichel, P; Dombernowsky, P; Hartmann, NR | 1 |
Arai, T; Ishiguro, K; Okamoto, K; Terao, K | 1 |
Furner, RL; Herren, TC; Mellett, LB | 1 |
Bergsagel, DE; Librach, SL; Ogawa, M | 1 |
Benedict, WF; Kouri, RE; Mark, C; Rucker, N | 1 |
Curby, WA; Rosenoer, VM | 1 |
Konopliannikov, AG | 1 |
Benedict, WF; Kouri, RE; Kurtz, SA; Price, PJ | 1 |
Menkes, JH; Yavin, E; Yavin, Z | 1 |
Harrap, KR; Mulder, JH | 1 |
O'Neill, FJ | 1 |
Keogh, B; Murphy, GP; Williams, P | 1 |
Gidoni, D; Hod, I; Schonfeld, S; Zimber, A | 1 |
Carchman, RA; Harris, LS; Munson, AE | 1 |
Bichel, P; Dombernowsky, P | 1 |
Agur, Z; Arnon, R; Schechter, B | 1 |
Dykes, DJ; Griswold, DP; Harrison, SD; Schmid, SM; Stevens, JJ; Waud, WR | 1 |
Bernacki, RJ; Hong, CI; Hui, SW; Rustum, Y; West, CR | 1 |
Arakawa, M; Ekimoto, H; Ishii, T; Kusama, K; Nagahata, T; Shibasaki, C; Takahashi, K; Uchida, T | 1 |
Nishimura, T; Okabe, T; Sato, I; Suzuki, H; Tanaka, N; Wu, RT; Yuan, BD | 1 |
Beitová, M; Grimová, J; Kargerová, A; Kejhová, I; Krepelka, J; Mĕlka, M; Miko, M; Pokorná, S; Reichlová, R; Sedivá, J | 1 |
Capizzi, RL | 1 |
Hartmann, HR; Hengartner, H; Rubas, W; Schott, H; Schwendener, RA; Supersaxo, A | 1 |
Hoth, DF; King, SA; Leyland-Jones, B; O'Dwyer, PJ | 1 |
Buckle, AM; Goepel, JR; Rees, RC | 1 |
Berdel, WE; Danhauser, S; Fink, U; Fromm, M; Hong, CI; Rastetter, J; Reichert, A; Schick, HD; West, CR | 1 |
Leyland-Jones, B; O'Dwyer, PJ | 1 |
Khoo, K; Kovnat, A; Selby, P; Tannock, I | 1 |
Bark, GA; Hunter, JM; Magin, RL; Niesman, MR | 1 |
Maurer-Schultze, B; Schäfer, E | 1 |
Bassukas, I; Fietkau, R; Schäfer, E; Schultze, B | 1 |
Goetz, I; Roberts, E; Sisken, BF | 1 |
Garin, AM; Lobova, TG; Preobrazhenskaia, MN; Zharkov, SA | 1 |
Seidel, HJ | 1 |
Frei, E | 1 |
Cihák, A; Veselỳ, J | 1 |
Goerttler, K; Kaufmann, M; Mattern, J; Volm, M; Wayss, K | 1 |
Lichter, W; Lopez, DM; Sigel, MM | 1 |
Kline, I | 1 |
Ablashi, DV; Dienhardt, F; Falk, L; Klein, G; Pearson, G; Rabin, H; Rabson, A; Wolfe, L | 1 |
Brockman, RW | 1 |
Evans, MJ; Yohn, DS | 1 |
Kemper, B; Rich, A | 1 |
Gilden, RV; Huebner, RJ; Kern, J | 1 |
Bhuyan, BK; Fraser, TJ; Scheidt, LG | 1 |
Temin, HM | 1 |
Gerber, P | 1 |
Buck, M; Cleeland, R; Grunberg, E; Prince, HN | 1 |
Durham, JP; Ives, DH | 1 |
Black, PH; Burns, WH | 1 |
Sambrook, J; Shatkin, AJ | 1 |
Defendi, V; Girardi, AJ | 1 |
Lewis, AM; Rowe, WP | 1 |
Hahn, E; Maruyama, Y; Schwartz, S; Thomson, JM | 1 |
Peterkofsky, B; Tomkins, GM | 1 |
Davies, DA | 1 |
Benoy, CJ; Elson, LA; Jones, M; Schneider, R | 1 |
LePage, GA | 1 |
Atwell, GJ; Cain, BF | 1 |
Cheeks, JB; Laster, WR; Schabel, FM; Skipper, HE; Trader, MW | 1 |
Dominick, CA; Dykes, DJ; Griswold, DP; Kelley, CA; Roberts, BJ | 1 |
Gutterman, JU; Hersh, EM; Mavligit, GM; Reed, RC | 1 |
Adamson, RH; Hahn, MA | 1 |
Borberg, H; Drahovsky, D; Kreis, W | 1 |
Cikes, M; Klein, G | 1 |
LePage, GA; White, SC | 1 |
Bhuyan, BK; Fraser, TJ; Gray, LG; Kuentzel, SL; Neil, GL | 1 |
Byfield, JE; Karlsson, U | 1 |
Cain, BF | 1 |
Benoy, CJ; Elson, LA; Schneider, R | 1 |
Bruce, WR; Lin, H | 1 |
Hoshi, A; Kanzawa, F; Kuretani, K | 1 |
Shapiro, WR | 1 |
Bertalanffy, FD; Gibson, MH | 1 |
Groth, DP; Horwitz, S; Vogler, WR | 1 |
Robins, RK; Tolman, RL | 1 |
Humphrey, EW; Mizuno, NS | 1 |
Goldenberg, DM | 1 |
Bruce, DL; Bruce, WR; Lin, HS | 1 |
Griswold, DP; Schabel, FM; Simpson-Herren, L | 1 |
Drahovsky, D; Kreis, W | 1 |
Campio, L | 1 |
Lucas, MB; Pittillo, RF | 1 |
Granoff, A; Kucera, LS | 1 |
Goldenberg, DM; Schricker, KT; Sögtrop, HH; von der Emde, J | 1 |
Katz, C; Melchionne, S; Sivak, A; Van Duuren, BL | 1 |
Baserga, R; McDonough, M; Sasaki, T; Shimkin, MB; Thatcher, D; Wieder, R | 1 |
Bather, R; Buck, BM | 1 |
Kreis, W; Uchida, K | 1 |
Kensler, CJ; Wodinsky, I | 1 |
Adamson, RH; Dixon, RL | 1 |
12 review(s) available for cytarabine and Experimental Neoplasms
Article | Year |
---|---|
Determinants of response to antimetabolites and their modulation by normal purine and pyrimidine metabolites.
Topics: Animals; Antimetabolites, Antineoplastic; Cytarabine; DNA, Neoplasm; Fluorodeoxyuridylate; Fluorouracil; Humans; Leukemia L1210; Neoplasms; Neoplasms, Experimental; Thymidine; Thymidylate Synthase; Uridine | 1981 |
Experimental basis for ciradian cancer chemotherapy.
Topics: Animals; Antineoplastic Agents; Cell Division; Circadian Rhythm; Cytarabine; Digestive System; Drug Administration Schedule; Humans; Mitosis; Neoplasms, Experimental | 1995 |
Rationale for adjuvant chemotherapy.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Carmustine; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Therapy, Combination; Female; Floxuridine; Fluorouracil; Humans; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental | 1977 |
Multiple basis of combination chemotherapy.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Antagonism; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Humans; Leucovorin; Mercaptopurine; Methotrexate; Neoplasms; Neoplasms, Experimental; Uridine | 1977 |
[Molecular mechanisms of the occurrence of tumor drug resistance and ways to overcome it].
Topics: Alkylating Agents; Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Cytarabine; Drug Resistance; Drug Synergism; Humans; Molecular Biology; Neoplasms; Neoplasms, Experimental; Phenotype; Purines; Pyrimidine Nucleosides; Pyrimidines | 1978 |
Role of thymidine in biochemical modulation: a review.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Cytarabine; Deoxycytidine Kinase; DNA Replication; DNA, Neoplasm; Drug Evaluation; Drug Synergism; Fluorouracil; Folic Acid Antagonists; Humans; Interphase; Kinetics; Leukemia; Methotrexate; Mice; Neoplasms; Neoplasms, Experimental; Nucleic Acid Synthesis Inhibitors; Nucleotides; Phosphonoacetic Acid; RNA, Neoplasm; Species Specificity; Thymidine | 1987 |
Biochemical modulation: application of laboratory models to the clinic.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Cytarabine; Dose-Response Relationship, Drug; Drug Evaluation; Fluorouracil; Humans; Methotrexate; Neoplasms, Experimental; Organophosphorus Compounds; Phosphonoacetic Acid; Thymidine | 1986 |
Combination cancer therapy: Presidential address.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Bleomycin; Cell Division; Cytarabine; DNA Replication; Hodgkin Disease; Humans; Immunosuppression Therapy; Leukemia, Lymphoid; Mice; Neoplasm Metastasis; Neoplasms; Neoplasms, Experimental; Prognosis; Remission, Spontaneous; Time Factors; Vincristine | 1972 |
Resistance of mammalian tumour cells toward pyrimidine analogues. A review.
Topics: Animals; Antimetabolites; Azacitidine; Azauridine; Bromouracil; Carcinoma, Ehrlich Tumor; Cell Line; Cricetinae; Cytarabine; Deoxycytidine; Drug Resistance; Fluorouracil; Genetic Code; Leukemia, Experimental; Leukemia, Lymphoid; Mast-Cell Sarcoma; Mice; Mutation; Neoplasms, Experimental; Oncogenic Viruses; Phosphotransferases; Pyrimidines; Sarcoma, Experimental; Selection, Genetic; Thymidine Kinase; Uracil; Virus Replication | 1973 |
Biochemical aspects of drug combinations.
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Bleomycin; Camptothecin; Cell Division; Cytarabine; Deferoxamine; Diamines; DNA, Neoplasm; Doxorubicin; Drug Therapy, Combination; Leukemia L1210; Macromolecular Substances; Mice; Neoplasms; Neoplasms, Experimental; Nitrosourea Compounds; Purine Nucleotides; Ribonucleotide Reductases; Thioguanine; Triazoles | 1974 |
Immunochemotherapy of human cancer.
Topics: Acute Disease; Adjuvants, Immunologic; Adult; Animals; Antineoplastic Agents; BCG Vaccine; Cytarabine; Humans; Immunosuppressive Agents; Immunotherapy; Leukemia L1210; Lymphoma; Melanoma; Mice; Neoplasms; Neoplasms, Experimental; Prednisone; Vincristine | 1974 |
Experimental cancer chemotherapy: strategy for cure.
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Half-Life; Haplorhini; Leukemia, Experimental; Mercaptopurine; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Transplantation, Homologous | 1971 |
176 other study(ies) available for cytarabine and Experimental Neoplasms
Article | Year |
---|---|
Glycosyltransferases and glycosidases in Morris hepatomas.
Topics: Animals; Carcinoma, Hepatocellular; Cell Differentiation; Cytidine Monophosphate N-Acetylneuraminic Acid; Female; Fucose; Glycoside Hydrolases; Guanosine Diphosphate Fucose; Hexosyltransferases; Liver Neoplasms; Male; Neoplasms, Experimental; Rats; Rats, Inbred ACI; Rats, Inbred BUF; Sialyltransferases | 1977 |
Specific alterations of fucoprotein biosynthesis in the plasma membrane of Morris hepatoma 7777.
Topics: Carcinoma, Hepatocellular; Cell Membrane; Fucose; Glycoproteins; Guanosine Diphosphate Fucose; Guanosine Diphosphate Mannose; Hexosamines; Hexoses; Liver; Liver Neoplasms; Neoplasms, Experimental | 1978 |
2'-Fluorinated isonucleosides. 1. Synthesis and biological activity of some methyl 2'-deoxy-2'-fluoro-2'-pyrimidinyl-D-arabinopyranosides.
Topics: Animals; Arabinonucleosides; Chemical Phenomena; Chemistry; Chemistry, Physical; Chlorine; Female; Fluorine; Humans; Kinetics; Leukemia L1210; Lung Neoplasms; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Molecular Conformation; Neoplasms, Experimental; Nucleotides; Sarcoma, Experimental; Tumor Cells, Cultured; Uracil; Viruses | 1989 |
Lipophilic 5'-(alkyl phosphate) esters of 1-beta-D-arabinofuranosylcytosine and its N4-acyl and 2,2'-anhydro-3'-O-acyl derivatives as potential prodrugs.
Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Cytarabine; Drug Resistance; Esters; Hydrolysis; Leukemia L1210; Melanoma; Mice; Neoplasms, Experimental | 1982 |
Phospholipid-nucleoside conjugates. 3. Syntheses and preliminary biological evaluation of 1-beta-D-arabinofuranosylcytosine 5'-monophosphate-L-1,2-dipalmitin and selected 1-beta-D-arabinofuranosylcytosine 5-diphosphate-L-1,2-diacylglycerols.
Topics: Animals; Antineoplastic Agents; Arabinonucleotides; Cell Division; Chemical Phenomena; Chemistry, Physical; Cytarabine; Diglycerides; Glycerides; Leukemia L1210; Mice; Multiple Myeloma; Neoplasms, Experimental | 1982 |
Discovery of coumarin derivatives as potent and selective cyclin-dependent kinase 9 (CDK9) inhibitors with high antitumour activity.
Topics: Animals; Antineoplastic Agents; Cell Proliferation; Coumarins; Cyclin-Dependent Kinase 9; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Female; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Mice, Nude; Models, Molecular; Molecular Structure; Neoplasms, Experimental; Protein Kinase Inhibitors; Structure-Activity Relationship | 2020 |
Aprepitant Sensitizes Acute Myeloid Leukemia Cells to the Cytotoxic Effects of Cytosine Arabinoside in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Aprepitant; Cell Cycle Checkpoints; Cell Proliferation; Cell Survival; Cytarabine; Drug Screening Assays, Antitumor; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Mice; Neoplasms, Experimental | 2020 |
UTX is an escape from X-inactivation tumor-suppressor in B cell lymphoma.
Topics: Animals; Antimetabolites, Antineoplastic; B-Lymphocytes; Brain Neoplasms; Carcinogenesis; Cytarabine; Drug Resistance, Neoplasm; Ephrin-B1; Female; Gene Dosage; Gene Expression Regulation, Neoplastic; Histone Demethylases; Humans; Lymphoma, B-Cell; Male; Mice; Mice, Knockout; Neoplasms, Experimental; Sex Factors; Signal Transduction; Survival Analysis; X Chromosome Inactivation | 2018 |
A CXCR4 antagonist leads to tumor suppression by activation of immune cells in a leukemia-induced microenvironment.
Topics: Adult; Aged; Aged, 80 and over; Animals; Apoptosis; Benzylamines; Bone Marrow Cells; Cell Movement; Chemokine CXCL12; Cyclams; Cytarabine; Female; Hematopoietic Stem Cells; Heterocyclic Compounds; Humans; Leukemia, Myeloid, Acute; Male; Mice; Middle Aged; Neoplasms, Experimental; Neoplastic Stem Cells; Receptors, CXCR4; Tumor Microenvironment | 2015 |
Molecular targeting therapy against promyelocytic leukemia protein using arsenic acids in experimental intracranial medulloblastoma.
Topics: Animals; Antineoplastic Agents; Arsenates; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Cerebellar Neoplasms; Cytarabine; Humans; Medulloblastoma; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Targeted Therapy; Neoplasms, Experimental; Nuclear Proteins; Oxides; Promyelocytic Leukemia Protein; Transcription Factors; Tumor Suppressor Proteins | 2012 |
Survival of acute myeloid leukemia cells requires PI3 kinase activation.
Topics: Acute Disease; Animals; Cell Survival; Cytarabine; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Everolimus; Humans; Leukemia, Myeloid; Mice; Mice, SCID; Neoplasms, Experimental; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Signal Transduction; Sirolimus; Transplantation, Heterologous | 2003 |
SYNERGISM OF THE ANTINEOPLASTIC ACTIVITY OF CYTOSINE ARABINOSIDE BY PORFIROMYCIN.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Body Weight; Cytarabine; Cytosine; Leukemia; Leukemia L1210; Leukemia, Experimental; Mice; Mitomycin; Mitomycins; Neoplasms; Neoplasms, Experimental; Nucleosides; Pharmacology; Porfiromycin; Research; Survival | 1964 |
THE REVERSAL OF CYTOSINE ARABINOSIDE ACTIVITY IN VIVO BY DEOXYCYTIDINE.
Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cytarabine; Cytosine; Deoxycytidine; Leukemia; Leukemia, Experimental; Neoplasms; Neoplasms, Experimental; Nucleosides; Pharmacology; Research; Sarcoma 180 | 1964 |
THE EFFECT OF 1-BETA-D-ARABINOFURANOSYLCYTOSINE HYDROCHLORIDE ON MURINE NEOPLASMS.
Topics: Animals; Anti-Bacterial Agents; Antibodies; Antineoplastic Agents; Blood Cells; Carcinoma, Ehrlich Tumor; Cortisone; Cytarabine; Cytosine; Leukemia L1210; Leukemia, Experimental; Lymphoma; Mercaptopurine; Methotrexate; Mice; Neoplasms; Neoplasms, Experimental; Pharmacology; Research; Sarcoma 180 | 1964 |
Oridonin, a diterpenoid extracted from medicinal herbs, targets AML1-ETO fusion protein and shows potent antitumor activity with low adverse effects on t(8;21) leukemia in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Apoptosis; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Core Binding Factor Alpha 2 Subunit; Cytarabine; Diterpenes; Diterpenes, Kaurane; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Leukemia, Myeloid, Acute; Mice; Mice, Nude; Neoplasms, Experimental; Oncogene Proteins, Fusion; Plant Extracts; Plants, Medicinal; RUNX1 Translocation Partner 1 Protein; Translocation, Genetic; U937 Cells | 2007 |
Synergistic antileukemia effect of genistein and chemotherapy in mouse xenograft model and potential mechanism through MAPK signaling.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cytarabine; Drug Synergism; Gene Expression Regulation, Neoplastic; Genistein; Humans; Leukemia; MAP Kinase Signaling System; Mice; Mice, SCID; Neoplasms, Experimental; Survival Rate; Transplantation, Heterologous; Tumor Burden | 2007 |
Nucleic acids. II. Cytotoxicity studies with nucleotides and dinucleoside phosphates containing ara-cytidine.
Topics: Animals; Antineoplastic Agents; Culture Techniques; Cytarabine; Cytosine Nucleotides; Leukemia, Experimental; Mice; Neoplasms, Experimental; Nucleosides; Nucleotides | 1967 |
Criteria associated with destruction of leukemia and solid tumor cells in animals.
Topics: Animals; Cricetinae; Cyclophosphamide; Cytarabine; Leukemia L1210; Methotrexate; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Nitroso Compounds; Urea | 1967 |
A comparison of three assays used for the in vitro chemosensitivity testing of human tumours.
Topics: Animals; Antineoplastic Agents; Bleomycin; Cell Line; Cell Survival; Cisplatin; Cytarabine; Dose-Response Relationship, Drug; Doxorubicin; Female; Fluorouracil; Humans; Leucine; Neoplasms, Experimental; Nucleotides; Rats | 1984 |
[Experimental research to clinical application of interferons].
Topics: Animals; Bleomycin; Cytarabine; Drug Therapy, Combination; Humans; Interferon Inducers; Interferon Type I; Interferon-gamma; Interferons; Leukemia, Experimental; Melanoma; Mice; Mitomycin; Mitomycins; Neoplasms; Neoplasms, Experimental | 1984 |
Differential and synergistic actions of nerve growth factor and cyclic AMP in PC12 cells.
Topics: Adrenal Gland Neoplasms; Animals; Bucladesine; Cell Differentiation; Cell Line; Cholera Toxin; Colchicine; Cyclic AMP; Cytarabine; Cytochalasin B; Drug Synergism; Neoplasms, Experimental; Nerve Growth Factors; Pheochromocytoma; Rats; RNA, Neoplasm | 1981 |
[Introduction of new screening system in National Cancer Institute].
Topics: Animals; Antineoplastic Agents; Cisplatin; Cricetinae; Cyclophosphamide; Cytarabine; Drug Evaluation, Preclinical; Female; Methotrexate; Mice; National Institutes of Health (U.S.); Neoplasms, Experimental; Rats; United States | 1984 |
Antitumor effects and pharmacology of orally administered N4-palmitoyl-1-beta-D-arabinofuranosylcytosine in mice.
Topics: Adenocarcinoma; Administration, Oral; Animals; Colonic Neoplasms; Cytarabine; Drug Evaluation, Preclinical; Leukemia L1210; Leukemia P388; Lung Neoplasms; Male; Mammary Neoplasms, Experimental; Melanoma; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Neoplasms, Experimental | 1984 |
Comparative growth of human tumors in pharmacologically immunosuppressed, immune-deprived, cyclosporin A-treated and nude mice.
Topics: Animals; Antilymphocyte Serum; Cyclophosphamide; Cyclosporins; Cytarabine; Humans; Male; Mice; Mice, Inbred C3H; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Procarbazine; T-Lymphocytes; Thymectomy; Transplantation, Heterologous; Whole-Body Irradiation | 1982 |
Relationship of chemotherapy on human cancer xenografts in nude mice to clinical response in donor patient.
Topics: Adult; Animals; Cytarabine; Drug Resistance; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Mice; Mice, Nude; Middle Aged; Mitomycins; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Tegafur; Transplantation, Heterologous | 1980 |
Effect of cytarabine on cytotoxic T-cell development.
Topics: Animals; Cell Line; Cells, Cultured; Cytarabine; Cytotoxicity, Immunologic; Interleukin-1; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasms, Experimental; Proteins; Spleen; T-Lymphocytes | 1982 |
Antibody-induced cell-cycle synchrony.
Topics: Animals; Antibodies, Neoplasm; Cell Cycle; Cells, Cultured; Cytarabine; Immunotherapy; Mice; Neoplasms, Experimental | 1983 |
Cell cycle arrest as a basis of enhancement of 1-beta-D-arabinofuranosylcytosine anabolism in human lymphoblastoid RPMI 6410 cells cultured with 3-deazauridine.
Topics: 3-Deazauridine; Cell Cycle; Cell Division; Cells, Cultured; Cytarabine; HeLa Cells; Humans; Kinetics; Lymphoma, Non-Hodgkin; Neoplasms, Experimental; Phosphorylation; Time Factors; Uridine | 1981 |
Influence of Ara-C on effector activity of cytotoxic T-lymphocytes in vitro.
Topics: Animals; Cytarabine; Cytotoxicity, Immunologic; Lymphoma; Mice; Neoplasms, Experimental; Spleen; T-Lymphocytes | 1981 |
Uptake of cytosine arabinoside (Ara-C) by LSA lymphoma after irradiation in the stationary phase of growth.
Topics: Adult; Animals; Cell Line; Cell Survival; Cytarabine; Humans; In Vitro Techniques; Lymphoma; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Time Factors | 1982 |
Effect of liposomally trapped antitumour drugs on a drug-resistant mouse lymphoma in vivo.
Topics: Animals; Antineoplastic Agents; Arabinofuranosylcytosine Triphosphate; Cell Survival; Cytarabine; Dose-Response Relationship, Drug; Drug Resistance; Liposomes; Lymphoma; Methotrexate; Mice; Mice, Inbred CBA; Neoplasms, Experimental | 1982 |
Liposomally trapped AraCTP to overcome AraC resistance in a murine lymphoma in vitro.
Topics: Animals; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cell Line; Cytarabine; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Resistance; Liposomes; Lymphoma; Mice; Neoplasms, Experimental; Thymidine | 1982 |
Drug control of Ara-C-resistant tumor cells.
Topics: 3-Deazauridine; Adenocarcinoma; Animals; Anthraquinones; Antimetabolites, Antineoplastic; Colonic Neoplasms; Cyclophosphamide; Cytarabine; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combination; Leukemia L1210; Mice; Mitoxantrone; Neoplasms, Experimental | 1982 |
The correlation of maximal drug dose, tumor recruitment, and sequence timing with therapeutic advantage: schedule-dependent toxicity of cytosine arabinoside.
Topics: Animals; Cytarabine; Drug Administration Schedule; Female; Neoplasms, Experimental; Rats | 1982 |
Synergistic lethal effect of cis-dichlorodiammineplatinum and 1-beta-D-arabinofuranosylcytosine.
Topics: Carcinoma; Cell Line; Cell Survival; Cisplatin; Colonic Neoplasms; Cytarabine; Dose-Response Relationship, Drug; Drug Synergism; Humans; Neoplasms, Experimental | 1981 |
Liposome-cell interactions. A study of the interactions of liposomes containing entrapped anti-cancer drugs with the EMT6, S49 and AE1 (transport-deficient) cell lines.
Topics: Animals; Biological Transport; Cell Line; Cytarabine; Dactinomycin; Female; Liposomes; Lymphoma; Mammary Neoplasms, Experimental; Methotrexate; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Phospholipids; Ribonucleosides; Tubercidin | 1981 |
Thymidine enhancement of 1-beta-d-arabinofuranosylcytosine activity for mouse EL4 tumors.
Topics: Animals; Cell Survival; Cytarabine; Drug Synergism; Drug Therapy, Combination; In Vitro Techniques; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neoplasms, Experimental; Thymidine; Thymoma; Transplantation, Isogeneic | 1981 |
Effect of thymidine on the toxicity, antitumor activity, and metabolism of 1-beta-D-arabinofuranosylcytosine in rats bearing a chemically induced colon carcinoma.
Topics: Animals; Arabinofuranosylcytosine Triphosphate; Biotransformation; Colonic Neoplasms; Cytarabine; Deoxycytidine; Drug Interactions; Drug Therapy, Combination; Female; Neoplasms, Experimental; Rats; Thymidine; Tissue Distribution | 1980 |
Human tumour xenografts established and serially transplanted in mice immunologically deprived by thymectomy, cytosine arabinoside and whole-body irradiation.
Topics: Animals; Cytarabine; Female; Humans; Immunosuppression Therapy; Karyotyping; Male; Melanoma; Mice; Mice, Inbred CBA; Microscopy, Electron; Neoplasm Transplantation; Neoplasms, Experimental; Ovarian Neoplasms; Radiation Effects; Thymectomy; Time Factors; Transplantation, Heterologous; Uterine Neoplasms | 1980 |
Influence of C. parvum on the effectiveness of passive serotherapy in the control of the EL4 lymphoma in C57BL/6 mice.
Topics: Animals; Cytarabine; Dose-Response Relationship, Immunologic; Immune Sera; Immunization, Passive; Injections, Intraperitoneal; Injections, Intravenous; Lymphoma; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Propionibacterium acnes | 1980 |
The cell population kinetics and response to an S-phase specific agent of three transplantable colon tumor lines.
Topics: Adenocarcinoma; Animals; Carcinoma; Cell Cycle; Cell Division; Colonic Neoplasms; Cytarabine; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Palmitates; Thymidine | 1980 |
Serotherapy of a spontaneous mouse tumour.
Topics: Animals; Cytarabine; Female; Immunization, Passive; Lymphoma; Mice; Mice, Inbred C57BL; Neoplasms, Experimental | 1980 |
High-performance liquid chromatographic analysis of cytosine arabinoside and metabolites in biological samples.
Topics: Animals; Arabinofuranosylcytosine Triphosphate; Arabinofuranosyluracil; Chromatography, High Pressure Liquid; Cytarabine; Female; Mice; Neoplasms, Experimental | 1980 |
Cytotoxic liponucleotide analogs. II. Antitumor activity of CDP-diacylglycerol analogs containing the cytosine arabinoside moiety.
Topics: Animals; Antineoplastic Agents; Cell Line; Cytarabine; Cytidine Diphosphate Diglycerides; Humans; Leukemia L5178; Leukemia P388; Mice; Neoplasms, Experimental; Nucleoside Diphosphate Sugars | 1980 |
Teaching cancer chemotherapy by means of a computer simulation.
Topics: Animals; Antineoplastic Agents; Carcinoma; Cause of Death; Computer Simulation; Computer-Assisted Instruction; Cyclophosphamide; Cytarabine; Drug Administration Schedule; Drug Screening Assays, Antitumor; Humans; Leukemia, Experimental; Melanoma; Methotrexate; Mice; Models, Biological; Models, Educational; Neoplasms, Experimental; Sarcoma, Experimental; Software; Survival Rate; Teaching | 1994 |
Polyamine increase in rat tissues treated with 1-beta-D-arabinosylcytosine and 5-fluorouracil.
Topics: Animals; Body Weight; Chromatography, High Pressure Liquid; Cytarabine; Fluorouracil; Male; Neoplasms, Experimental; Organ Size; Polyamines; Rats; Rats, Sprague-Dawley | 1993 |
Determinants in chemosensitivity of oncogene-transformed NIH3T3 cells to 2'-C-cyano-2'-deoxy-1-beta-D-arabinofuranosylcytosine.
Topics: 3T3 Cells; Animals; Antineoplastic Agents; Cell Division; Cell Transformation, Neoplastic; Chick Embryo; Cytarabine; Cytidine Deaminase; Deoxycytidine Kinase; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Oncogenes; Transformation, Genetic; Tritium | 1999 |
Antitumor activity and novel DNA-self-strand-breaking mechanism of CNDAC (1-(2-C-cyano-2-deoxy-beta-D-arabino-pentofuranosyl) cytosine) and its N4-palmitoyl derivative (CS-682).
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Arabinonucleosides; Biotransformation; Breast Neoplasms; Cisplatin; Cytarabine; Cytosine; Deoxycytidine; Deoxycytidine Kinase; DNA Damage; DNA, Neoplasm; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Fluorouracil; Humans; KB Cells; Leukemia P388; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Mice, Nude; Mitomycin; Molecular Structure; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Rats, Nude; Specific Pathogen-Free Organisms; Stomach Neoplasms; Tumor Cells, Cultured; Vincristine | 1999 |
Aneuploidy precedes and segregates with chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aneuploidy; Animals; Carcinogens; Cell Line, Transformed; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Cricetulus; Cytarabine; DNA Mutational Analysis; Humans; Karyotyping; Male; Methylcholanthrene; Models, Biological; Neoplasms, Experimental; Precancerous Conditions; Time Factors | 2000 |
Anti-neovascular therapy by liposomal DPP-CNDAC targeted to angiogenic vessels.
Topics: Amino Acid Sequence; Angiogenesis Inhibitors; Animals; Cytarabine; Drug Delivery Systems; Liposomes; Male; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms, Experimental; Neovascularization, Pathologic; Oligopeptides; Phosphatidic Acids; Survival Analysis; Time Factors; Tissue Distribution; Treatment Outcome; Tumor Cells, Cultured | 2002 |
Comparison of enzymatic activities of two deoxycytidine kinases purified from cells sensitive (P815) or resistant (P815/ara-C) to 1-beta-D-arabinofuranosylcytosine.
Topics: Animals; Cytarabine; Deoxycytidine; Drug Resistance; Hydrogen-Ion Concentration; In Vitro Techniques; Isoenzymes; Kinetics; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasms, Experimental; Phosphotransferases; Substrate Specificity; Temperature | 1978 |
Chemotherapeutic drugs increase killing of tumor cells by antibody and complement.
Topics: Animals; Antigen-Antibody Reactions; Antineoplastic Agents; Azacitidine; Carcinoma, Hepatocellular; Cell Line; Complement System Proteins; Cyclophosphamide; Cytarabine; Fluorouracil; Guinea Pigs; Liver Neoplasms; Methotrexate; Neoplasms, Experimental; Nitrosamines; Vincristine | 1975 |
[Experimental studies on effects of carcinostatic agents (author's transl)].
Topics: Animals; Bleomycin; Carcinoma, Transitional Cell; Cytarabine; Mitomycins; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Rats, Inbred ACI; Transplantation, Homologous; Urinary Bladder Neoplasms | 1975 |
Enhancing effect by metabolic inhibitors on the killing of tumor cells by antibody and complement.
Topics: Animals; Antibodies, Neoplasm; Antigen-Antibody Reactions; Antineoplastic Agents; Azacitidine; Carcinoma, Hepatocellular; Cells, Cultured; Complement System Proteins; Cyclophosphamide; Cytarabine; Dactinomycin; Doxorubicin; Fluorouracil; Guinea Pigs; Hydroxyurea; Liver Neoplasms; Mercaptopurine; Methotrexate; Mitomycins; Neoplasms, Experimental; Puromycin; Vincristine | 1975 |
Beta-glucuronidase activity of Yoshida ascites hepatomas of different drug-sensitivity and its change after treatment of host rats with various anticancer agents.
Topics: Animals; Antineoplastic Agents; Bleomycin; Carbazilquinone; Carcinoma, Hepatocellular; Chromomycins; Cyclophosphamide; Cytarabine; Daunorubicin; Deoxyribonucleases; Fluorouracil; Glucuronidase; Liver Neoplasms; Male; Mesylates; Mitomycins; Neoplasms, Experimental; Nitro Compounds; Rats; Sarcoma, Yoshida; Tosyl Compounds; Vincristine; Zinostatin | 1976 |
Comparison of 2,2'-anhydro-1-beta-D-arabinofuranosyl-5-fluorocytosine and cytosine arabinoside in the treatment of murine brain tumor.
Topics: Ancitabine; Animals; Brain Neoplasms; Cell Survival; Cytarabine; DNA, Neoplasm; Lethal Dose 50; Mice; Neoplasms, Experimental; Thymidine | 1976 |
In vitro induction of polyclonal killer T cells with 2-mercaptoethanol and the essential role of macrophages in this process.
Topics: Animals; Antigens, Neoplasm; Burkitt Lymphoma; Cell Division; Cells, Cultured; Clone Cells; Cytarabine; Cytotoxicity Tests, Immunologic; DNA; Epitopes; Female; Hydroxyurea; Immunity, Cellular; In Vitro Techniques; Leukemia, Experimental; Macrophages; Mast-Cell Sarcoma; Mercaptoethanol; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Plasmacytoma; T-Lymphocytes | 1977 |
Pharmacokinetic studies of a transplantable murine renal adenocarcinoma.
Topics: Adenocarcinoma; Animals; Bleomycin; Carmustine; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Evaluation, Preclinical; Kidney Neoplasms; Lomustine; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms, Experimental | 1977 |
Comparative study of early effects of epipodophyllotoxin derivatives and other cytostatic agents on mastocytoma cultures.
Topics: Antineoplastic Agents; Bleomycin; Cell Division; Cell Line; Colchicine; Cytarabine; DNA, Neoplasm; Etoposide; Mast-Cell Sarcoma; Mechlorethamine; Mercaptopurine; Methotrexate; Mitosis; Neoplasm Proteins; Neoplasms, Experimental; Podophyllotoxin; Razoxane; RNA, Neoplasm; Teniposide; Vincristine; X-Rays | 1977 |
Distribution and excretion of 14C-cyclocytidine in experimental animals.
Topics: Administration, Oral; Ancitabine; Animals; Biotransformation; Cytarabine; Dogs; Drug Stability; Female; Haplorhini; Injections, Intravenous; Intestinal Absorption; Macaca mulatta; Male; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Rats; Species Specificity; Time Factors | 1977 |
Differential sensitivities of five rat hepatoma cell lines to anticancer drugs.
Topics: Animals; Antineoplastic Agents; Bleomycin; Carcinoma, Hepatocellular; Cell Line; Cell Survival; Cytarabine; Doxorubicin; Drug Resistance; Hydroxyurea; Liver Neoplasms; Lomustine; Neoplasms, Experimental; Rats; Semustine | 1978 |
Effect of chemotherapeutic agents on the growth of rat bladder cancer, BC-47.
Topics: Animals; Antineoplastic Agents; Bleomycin; Carmustine; Cytarabine; Doxorubicin; Fluorouracil; Mitomycins; Neoplasms, Experimental; Nitrogen Mustard Compounds; Rats; Urinary Bladder Neoplasms; Vincristine | 1978 |
Human gastrointestinal cancer grown in nude mice used to test new chemotherapeutic agents.
Topics: Abrin; Ancitabine; Animals; Colonic Neoplasms; Cytarabine; Drug Evaluation, Preclinical; Female; Fluorouracil; Humans; Male; Mice; Mice, Nude; Neoplasms, Experimental; Ricin | 1979 |
Stimulation of human chorionic gonadotropin by JAr line choriocarcinoma after inhibition of DNA synthesis.
Topics: Cell Line; Choriocarcinoma; Chorionic Gonadotropin; Cycloheximide; Cytarabine; DNA, Neoplasm; Dose-Response Relationship, Drug; Female; Floxuridine; Humans; Hydroxyurea; Methotrexate; Neoplasm Proteins; Neoplasms, Experimental; Pregnancy; Uterine Neoplasms | 1979 |
Kinase and deaminase activity in a variety of subcutaneous mouse tumors.
Topics: Adenocarcinoma; Aminohydrolases; Animals; Cell Line; Chick Embryo; Cytarabine; Freezing; Glioma; Lung Neoplasms; Mammary Neoplasms, Experimental; Melanoma; Mice; Mice, Inbred AKR; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasms, Experimental; Osteosarcoma; Phosphotransferases; Pyrimidine Nucleotides; Sarcoma 180; Tetrahydrouridine; Uridine | 1975 |
The mechanism of action of 3-deazauridine in tumor cells sensitive and resistant to arabinosylcytosine.
Topics: 3-Deazauridine; Adenocarcinoma; Animals; Cell Line; Cytarabine; Deoxycytidine; Deoxyribonucleotides; DNA, Neoplasm; Drug Resistance; Leukemia L1210; Liver; Mice; Neoplasms, Experimental; Orotic Acid; Phosphotransferases; Pyrimidine Nucleotides; Ribonucleotide Reductases; Ribonucleotides; RNA, Neoplasm; Uracil Nucleotides; Uridine | 1975 |
Biology of SV40 transplantation antigen (TrAg). I. Demonstration of SV40 TrAg on glutaraldehyde-fixed SV40-infected African green monkey kidney cells.
Topics: Animals; Antigens, Viral; Cell Line; Cytarabine; Dactinomycin; DNA, Viral; Glutaral; Haplorhini; Histocompatibility Antigens; Immunity; Mice; Mice, Inbred BALB C; Mutation; Neoplasm Transplantation; Neoplasms, Experimental; Simian virus 40; Temperature; Virus Replication | 1976 |
Cytosine-arabinoside does not inhibit incorporation of 3H-thymidine in herpes simplex virus transformed cells.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Cytarabine; DNA, Neoplasm; Neoplasms, Experimental; Simian virus 40; Simplexvirus; Thymidine | 1977 |
Physiologic disposition of cytosine arabinoside and its derivatives in man.
Topics: Administration, Oral; Cytarabine; Deamination; Deoxycytidine; Humans; In Vitro Techniques; Injections, Intravenous; Neoplasms, Experimental; Phosphotransferases; Time Factors | 1977 |
Metabolism and intracellular retention of 1-beta-D-arabinofuranosylcytosine as predictors of response of animal tumors.
Topics: Animals; Carcinoma, Hepatocellular; Cytarabine; Female; Leukemia L1210; Leukemia, Experimental; Liver Neoplasms; Mice; Mice, Inbred DBA; Neoplasms, Experimental; Tissue Distribution | 1978 |
Transport and metabolism of deoxycytidine and 1-beta-D-arabinofuranosylcytosine into cultured Novikoff rat hepatoma cells, relationship to phosphorylation, and regulation of triphosphate synthesis.
Topics: Animals; Biological Transport, Active; Carcinoma, Hepatocellular; Cells, Cultured; Cytarabine; Deoxycytidine; Deoxyribonucleotides; DNA, Neoplasm; Feedback; Hydroxyurea; Liver Neoplasms; Neoplasms, Experimental; Oxidative Phosphorylation; Rats; Thymidine | 1978 |
Multiple determinants of antimetabolite action in humans.
Topics: Animals; Antimetabolites, Antineoplastic; Arabinofuranosylcytosine Triphosphate; Arabinofuranosyluracil; Cytarabine; Daunorubicin; Deamination; DNA; Doxorubicin; Drug Resistance; Humans; Leukemia, Myeloid, Acute; Neoplasms, Experimental | 1979 |
The inhibition of DNA sythesis in vitamin-E-depleted lymphosarcoma cells by X-rays and cytostatics.
Topics: Animals; Cytarabine; Diet; DNA, Neoplasm; Doxorubicin; Lymphoma, Non-Hodgkin; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neoplasms, Experimental; Radiation Effects; Splenic Neoplasms; Vitamin E; X-Rays | 1977 |
Stimulating factors and cell recruitment in murine bone marrow stem cells and EMT6 tumours.
Topics: Animals; Bone Marrow Cells; Cell Cycle; Cells, Cultured; Colony-Stimulating Factors; Cytarabine; DNA; DNA, Neoplasm; Female; Hematopoietic Stem Cells; In Vitro Techniques; Mice; Neoplasms, Experimental | 1978 |
Evidence for a new mechanism of cytotoxicity of 1-beta-D arabinofuranosylcytosine.
Topics: Cell Cycle; Cell Line; Cell Survival; Chromosome Aberrations; Cytarabine; DNA; DNA Replication; Humans; Lymphocytes; Models, Biological; Neoplasms, Experimental | 1979 |
[Chemotherapy in solid transplantation tumors following synchronization (author's transl)].
Topics: Animals; Carcinoma 256, Walker; Cell Cycle; Cyclophosphamide; Cytarabine; Hydroxyurea; Male; Neoplasms, Experimental; Neurofibroma; Rats; Time Factors; Vincristine | 1979 |
Combinations of tetrahydrouridine and cytosine arabinoside in mouse tumors.
Topics: Adenocarcinoma; Animals; Cytarabine; Cytidine Deaminase; Deamination; Drug Evaluation; Drug Therapy, Combination; Female; Lung Neoplasms; Mice; Neoplasms, Experimental; Phosphotransferases; Sarcoma, Experimental; Tetrahydrouridine; Tritium; Uridine | 1977 |
Biochemical and clinical studies of chronic lymphocytic leukemia.
Topics: Aged; Animals; Chronic Disease; Cytarabine; DNA, Neoplasm; Humans; In Vitro Techniques; Leukemia, Lymphoid; Male; Mercaptopurine; Mice; Middle Aged; Neoplasms, Experimental; Ribonucleotides; RNA, Neoplasm | 1978 |
Structural comparison of deoxycytidine kinases purified from cells sensitive (P815) or resistant (P815/ara-C) to 1-beta-D-arabinofuranosylcytosine.
Topics: Amino Acids; Animals; Chloromercuribenzoates; Cyanogen Bromide; Cytarabine; Deoxycytidine; Drug Resistance; Isoenzymes; Mice; Molecular Weight; Neoplasms, Experimental; Phosphotransferases; Structure-Activity Relationship | 1978 |
Growth inhibition of normal or drug-treated lymphoma cells in lethally irradiated mice.
Topics: Animals; Antigens, Neoplasm; Cytarabine; Dacarbazine; Female; Graft Rejection; H-2 Antigens; Immunity; Lymphoma; Male; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Transplantation, Homologous; Triazenes | 1978 |
Proliferation kinetics of a human breast cancer line in vitro following treatment with 17beta-estradiol and 1-beta-D-arabinofuranosylcytosine.
Topics: Breast Neoplasms; Cell Cycle; Cell Division; Cell Line; Cytarabine; Dose-Response Relationship, Drug; Drug Interactions; Estradiol; Female; Humans; Kinetics; Neoplasms, Experimental; Receptors, Estrogen | 1978 |
Growth and inhibition of mouse or human tumors in "nude" (athymic) mice monitored by the extent of 125 I-5-Iodo-2'-deoxyuridine(125-IUdR) uptake.
Topics: Animals; Cyclophosphamide; Cytarabine; Doxorubicin; Female; Fluorouracil; HeLa Cells; Humans; Idoxuridine; Mice; Mice, Inbred C57BL; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosourea Compounds; Transplantation, Heterologous; X-Rays | 1978 |
Effect of thymidine on the sensitivity of cultured mouse tumor cells to 1-beta-D-arabinofuranosylcytosine.
Topics: Cell Line; Cytarabine; Deoxycytosine Nucleotides; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Neoplasms, Experimental; Thymidine | 1979 |
Murine pulmonary adenoma bioassay of potentially effective agents against slow-growing solid tumors.
Topics: Adenoma; Animals; Antineoplastic Agents; Cell Division; Cell Survival; Cells, Cultured; Cytarabine; Doxorubicin; Drug Evaluation, Preclinical; Female; Humans; Hydroxyurea; Lung Neoplasms; Male; Mice; Mice, Inbred A; Neoplasms, Experimental; Urethane | 1977 |
Nucleosides. 102. Synthesis of some 3'-deoxy-3'-substituted arabinofuranosylpyrimidine nucleosides.
Topics: Cells, Cultured; Cytarabine; Deoxyribonucleosides; Drug Evaluation, Preclinical; Neoplasms, Experimental; Pyrimidine Nucleosides | 1977 |
Identification of early proteins induced by highly oncogenic human adenovirus 12 during lytic infection and in hamster tumors.
Topics: Adenoviruses, Human; Animals; Cell Line; Cricetinae; Cycloheximide; Cytarabine; Molecular Weight; Neoplasms, Experimental; Osmolar Concentration; Protein Biosynthesis; Viral Proteins | 1977 |
Cell cycle-specific oncogenic transformation of C3H/10T1/2 clone 8 mouse embryo cells by 1-beta-D-arabinofuranosylcytosine.
Topics: Animals; Carcinogens; Cell Division; Cell Line; Cell Transformation, Neoplastic; Chromosomes; Cytarabine; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms, Experimental; Transplantation, Isogeneic | 1977 |
The principles and methods of cell synchronization in cancer chemotherapy.
Topics: Animals; Cell Division; Cell Line; Colchicine; Computers; Cytarabine; DNA Replication; Esophagus; Humans; Intestine, Small; Kinetics; Lasers; Mathematics; Mice; Mitosis; Models, Biological; Neoplasm Metastasis; Neoplasms; Neoplasms, Experimental; Organ Specificity; Thymidine; Time Factors | 1976 |
Combination therapy with mitomycin C,5-fluorouracil, and cytosine arabinoside in P815 ascites and solid mouse neoplasms.
Topics: Animals; Cytarabine; Drug Therapy, Combination; Fluorouracil; Mice; Mitomycins; Neoplasms, Experimental | 1976 |
Pharmacokinetic studies in the chemotherapy of neuroblastoma using the C1300 murine system.
Topics: Animals; Antineoplastic Agents; Carmustine; Cyclophosphamide; Cytarabine; DNA, Neoplasm; Doxorubicin; Drug Evaluation, Preclinical; Male; Mice; Mice, Inbred A; Neoplasms, Experimental; Neuroblastoma; RNA, Neoplasm | 1976 |
Resting cells in L1210 and JB-1 ascites tumors with special emphasis on recycling.
Topics: Animals; Cell Division; Cell Survival; Cytarabine; DNA, Neoplasm; Kinetics; Leukemia L1210; Mice; Mitotic Index; Models, Biological; Neoplasm Transplantation; Neoplasms, Experimental; Time Factors | 1976 |
HeLa cell-tumor in nude mice and its response to antitumor agents.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Drug Evaluation, Preclinical; Fluorouracil; HeLa Cells; Mice; Mice, Nude; Mitomycins; Neoplasm Transplantation; Neoplasms, Experimental; Transplantation, Heterologous | 1976 |
Influence of tetrahydrouridine on the phosphorylation of 1-beta-D-arabinofuranosyl-cytosine (ara-C) by enzymes from solid tumors in vitro.
Topics: Adenocarcinoma; Animals; Bone Neoplasms; Cytarabine; Cytidine Deaminase; Deoxycytidine; Female; In Vitro Techniques; Kinetics; L Cells; Liver; Lung Neoplasms; Male; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Osteosarcoma; Phosphorus; Phosphotransferases; Sarcoma 180; Spleen; Tetrahydrouridine; Uridine | 1975 |
Further considerations in the therapy with ara-C.
Topics: Animals; Cytarabine; Drug Resistance; Drug Synergism; Fluorouracil; Mice; Mitomycins; Neoplasms, Experimental; Thioguanine | 1975 |
Mouse myeloma. A model for studies of cell kinetics.
Topics: Alkylating Agents; Animals; Bone Marrow; Bone Marrow Cells; Bone Neoplasms; Cell Division; Cells, Cultured; Cyclophosphamide; Cytarabine; Disease Models, Animal; Kinetics; Melphalan; Methotrexate; Mice; Mice, Inbred BALB C; Myeloma Proteins; Neoplasms, Experimental; Plasmacytoma; Thymidine; Tritium; Vinblastine; Vincristine | 1975 |
Correlation between balance of specific chromosomes and expression of malignancy in hamster cells.
Topics: Animals; Animals, Newborn; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Chromosome Aberrations; Cricetinae; Cytarabine; Fibrosarcoma; Karyotyping; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosamines; Transplantation, Homologous | 1975 |
Growth kinetics of solid tumors. Implications for chemotherapy.
Topics: Acute Disease; Adenocarcinoma; Animals; Antineoplastic Agents; Cell Division; Colonic Neoplasms; Culture Techniques; Cytarabine; DNA; Humans; Kinetics; Leukemia; Meiosis; Melanoma; Mitosis; Neoplasms; Neoplasms, Experimental; Rats; Thymidine; Tritium; Vinblastine | 1975 |
[Suppression of postradiation regeneration as one of possible ways of increasing tumor cell destruction].
Topics: Animals; Cytarabine; Dactinomycin; DNA Repair; DNA Replication; DNA, Neoplasm; Neoplasms, Experimental; Radiation Effects | 1975 |
1-beta-D-arabinofuranosylcytosine-induced malignant transformation of hamster and rat cells in culture.
Topics: Animals; Benzopyrenes; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Cytarabine; DNA; Fetus; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Transplantation, Homologous | 1975 |
Polyunsaturated fatty acid metabolism in neuroblastoma cells in culture.
Topics: Animals; Cell Membrane; Clone Cells; Cytarabine; Linoleic Acids; Linolenic Acids; Lipids; Mice; Neoplasms, Experimental; Neuroblastoma; Phospholipids | 1975 |
Cytosine arabinoside uptake by tumour cells in vitro.
Topics: Animals; Cytarabine; Deoxycytidine; Diffusion; Female; In Vitro Techniques; Kinetics; Leukemia L1210; Leukemia, Experimental; Neoplasms, Experimental; Rats; Sarcoma, Yoshida | 1975 |
Selective destruction of cultured tumor cells with uncontrolled nuclear division by cytochalasin B and cytosine arabinoside.
Topics: Animals; Cell Division; Cell Line; Cell Nucleus; Cell Survival; Cells, Cultured; Cricetinae; Cytarabine; Cytochalasin B; Fibroblasts; Humans; In Vitro Techniques; Neoplasms, Experimental; Rhabdomyosarcoma; Time Factors | 1975 |
Chemotherapy of a murine neuroblastoma model.
Topics: Animals; Cell Line; Cytarabine; Disease Models, Animal; Doxorubicin; Drug Administration Schedule; Mice; Mice, Inbred A; Neoplasms, Experimental; Neuroblastoma | 1975 |
Solid intraperitoneal Landschütz tumour in mice: implications in cancer chemotherapy and immunology studies.
Topics: Animals; Cycloheximide; Cyclophosphamide; Cytarabine; Immune Sera; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms, Experimental; Transplantation, Homologous | 1975 |
The inhibition of DNA synthesis by cannabinoids.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Cannabidiol; Cannabis; Cyclophosphamide; Cytarabine; DNA; DNA, Neoplasm; Dronabinol; Fluorouracil; Idoxuridine; Leukemia L1210; Lung Neoplasms; Mice; Neoplasms, Experimental; Semustine | 1976 |
Recycling of resting cells in the JB-1 ascites tumour after treatment with 1-beta-D-arabinofuranosylcytosine (ara-C).
Topics: Animals; Autoradiography; Cell Division; Cytarabine; DNA, Neoplasm; Male; Mice; Mice, Inbred Strains; Mitotic Index; Neoplasms, Experimental; Plasmacytoma; Spectrophotometry; Thymidine | 1976 |
Effect of the dosing interval on myelotoxicity and survival in mice treated by cytarabine.
Topics: Animals; Bone Marrow; Cell Cycle; Cytarabine; Drug Administration Schedule; Lymphoma; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Tumor Cells, Cultured | 1992 |
Evaluation of combinations of interferons and cytotoxic drugs in murine tumor models in vivo.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cytarabine; Doxorubicin; Drug Screening Assays, Antitumor; Female; Interferon Type I; Interferon-gamma; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasms, Experimental | 1990 |
Formulation, stability, and antitumor activity of 1-beta-D-arabinofuranosylcytosine conjugate of thioether phospholipid.
Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Cytarabine; Drug Stability; Female; Freeze Fracturing; Leukemia L1210; Male; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Microscopy, Electron; Molecular Structure; Neoplasms, Experimental; Phospholipid Ethers; Sarcoma, Experimental | 1990 |
[Antitumor activity of a novel analog of cytarabine, 4-amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone 5'-(sodium octadecyl phosphate) monohydrate (YNK01)].
Topics: Administration, Oral; Animals; Antineoplastic Agents; Arabinonucleotides; Cytarabine; Cytidine Monophosphate; Cytosine Nucleotides; Drug Administration Schedule; Drug Screening Assays, Antitumor; Female; Injections, Intraperitoneal; Injections, Intravenous; Leukemia L1210; Male; Mice; Neoplasms, Experimental; Tumor Cells, Cultured | 1990 |
Biological activity of cadeguomycin. Inhibition of tumor growth and metastasis, immunostimulation, and potentiation of 1-beta-D-arabinofuranosylcytosine.
Topics: Adjuvants, Immunologic; Animals; Antibiotics, Antineoplastic; Cytarabine; Drug Synergism; Female; Guanosine; Humans; Interferons; Interleukin-1; Lung Neoplasms; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Phagocytosis | 1985 |
Substances with antineoplastic activity. XCVI. Some pharmacological properties and therapeutic synergism of 6-purinyl-N-(2-chloroethyl)thiocarbamate with cytosine arabinoside.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; DNA, Neoplasm; Female; Lymphoma, Large B-Cell, Diffuse; Melanoma, Experimental; Mercaptopurine; Mice; Mice, Inbred C57BL; Mustard Compounds; Neoplasms, Experimental; Rats; Rats, Inbred Strains; RNA, Neoplasm | 1989 |
New cytarabine analogs.
Topics: Animals; Biological Transport; Cytarabine; Drug Evaluation, Preclinical; Drug Resistance; Humans; Mice; Molecular Structure; Neoplasms; Neoplasms, Experimental | 1989 |
[Liposomes as carriers of lipophilic cytosine arabinoside and fluorodeoxyuridine derivatives. Their cytostatic effect and possibilities of tumor cell specific therapy].
Topics: Animals; Antibodies, Monoclonal; Cytarabine; Drug Therapy; Floxuridine; Humans; Leukemia L1210; Liposomes; Mice; Neoplasms, Experimental; Organ Specificity; Prodrugs | 1987 |
The effect of the immune status of the TAR mouse on the growth and metastasis of tumour xenografts.
Topics: Animals; Bone Marrow; Cytarabine; Female; Immunocompetence; Immunosuppression Therapy; Killer Cells, Natural; Mice; Mice, Inbred CBA; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Spleen; Thymectomy; Time Factors; Whole-Body Irradiation | 1987 |
Antineoplastic activity of conjugates of lipids and 1-beta-D-arabinofuranosylcytosine.
Topics: Animals; Antineoplastic Agents; Carcinoma; Cell Survival; Cytarabine; Dose-Response Relationship, Drug; Humans; Lung Neoplasms; Mice; Mice, Inbred C57BL; Molecular Conformation; Neoplasm Metastasis; Neoplasms, Experimental; Phospholipid Ethers; Tumor Cells, Cultured | 1987 |
Methods of immunosuppression for study of growth and lung colony formation by human tumor cells in mice.
Topics: Animals; Antilymphocyte Serum; Carrageenan; Cyclophosphamide; Cyclosporins; Cytarabine; Estradiol; Female; Immunosuppression Therapy; Killer Cells, Natural; Lung Neoplasms; Male; Methylprednisolone; Mice; Mice, Inbred CBA; Neoplasm Transplantation; Neoplasms, Experimental; Thymectomy; Transplantation, Heterologous; Whole-Body Irradiation | 1986 |
Effect of vesicle size on the clearance, distribution, and tumor uptake of temperature-sensitive liposomes.
Topics: Animals; Cytarabine; Female; Liposomes; Metabolic Clearance Rate; Methotrexate; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Particle Size; Temperature; Tissue Distribution | 1986 |
Cytocidal and toxic effect of various cytostatic drugs on three ascites tumors of the mouse.
Topics: Animals; Antineoplastic Agents; Ascites; Carcinoma, Ehrlich Tumor; Cisplatin; Cyclophosphamide; Cytarabine; Female; Mice; Neoplasms, Experimental; Vincristine | 1987 |
Cell kinetic studies of the effect of cytotoxic drugs on survival and proliferation of ascites and solid tumor cells of the mouse.
Topics: Adenocarcinoma; Animals; Ascites; Carcinoma, Ehrlich Tumor; Cell Cycle; Cell Survival; Cyclophosphamide; Cytarabine; Interphase; Leukemia L1210; Mice; Necrosis; Neoplasms, Experimental | 1985 |
Triethanolamine, tris, hepes, and cytosine arabinoside show neuritogenic activity in cultured chick embryo ganglia.
Topics: Animals; Buffers; Cells, Cultured; Chick Embryo; Cytarabine; Ethanolamines; Ganglia, Spinal; HEPES; Neoplasms, Experimental; Nerve Growth Factors; Nerve Regeneration; Neurons; Pheochromocytoma; Tromethamine | 1985 |
[Ribamidyl (ribavirin) as a modulator of the biological action of arabinosylcytosine and methotrexate].
Topics: Animals; Cytarabine; Drug Evaluation, Preclinical; Drug Synergism; Methotrexate; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Ribavirin; Ribonucleosides | 1985 |
[Estimation of tumor sensitivity in vitro. II. Studies with the solid Ehrlich carcinoma of the mouse and the GW 77, a heterotransplanted human carcinoma].
Topics: Animals; Antibiotics, Antineoplastic; Autoradiography; Carcinoma; Carcinoma, Ehrlich Tumor; Colonic Neoplasms; Cricetinae; Culture Media; Cytarabine; Dactinomycin; DNA, Neoplasm; Humans; Hydroxyurea; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Nucleosides; RNA, Neoplasm; Thymidine; Triaziquone; Tritium; Uridine | 1970 |
[Selective tumour chemotherapy using oncobiograms (author's transl)].
Topics: Animals; Antineoplastic Agents; Bleomycin; Cricetinae; Culture Techniques; Cytarabine; Dactinomycin; Daunorubicin; Doxorubicin; Drug Evaluation; Drug Resistance; Fluorouracil; Humans; Methods; Methotrexate; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Procarbazine; Radioisotopes; Rats; Scintillation Counting; Thymidine; Triaziquone; Uridine | 1974 |
In vitro methods to complement in vivo approaches utilizing combinations of chemotherapy and immunotherapy.
Topics: Animals; Antigens, Neoplasm; Antineoplastic Agents; Bleomycin; Carmustine; Cells, Cultured; Chickens; Clone Cells; Concanavalin A; Culture Techniques; Cytarabine; Cytological Techniques; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Humans; Immunity, Cellular; Immunotherapy; Lectins; Lipopolysaccharides; Lymphocytes; Melanoma; Mice; Mitosis; Neoplasms; Neoplasms, Experimental; Thymidine | 1974 |
Potentially useful combinations of chemotherapy detected in mouse tumor systems.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Azauridine; Bleomycin; Camptothecin; Cyclic P-Oxides; Cyclophosphamide; Cytarabine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Ethylamines; Fluorouracil; Imidazoles; Leukemia L1210; Lung Neoplasms; Methotrexate; Mice; Neoplasms, Experimental; Oxazines; Piperazines; Procarbazine; Propane; Triazenes | 1974 |
Antibody reactions to herpesvirus saimiri (HVS)-induced early and late antigens (EA and LA) in HVS-infected squirrel, marmoset and owl monkeys.
Topics: Animals; Antibodies, Anti-Idiotypic; Antibodies, Viral; Antibody Formation; Antigen-Antibody Complex; Antigen-Antibody Reactions; Antigens, Viral; Cells, Cultured; Culture Media; Cytarabine; Fluorescent Antibody Technique; Haplorhini; Herpesviridae; Immune Sera; Immunoglobulin E; Leukocyte Count; Lymphocytes; Lymphoma; Neoplasm Transplantation; Neoplasms, Experimental; Oncogenic Viruses; Staining and Labeling; Time Factors; Transplantation, Homologous | 1973 |
Application of the paired radioiodine-labeled antibody technique (PRILAT) to the detection of adenovirus 12 tumor (T) antigen.
Topics: Adenoviridae; Animals; Antibodies; Antigens; Carcinoma; Cell Line; Complement Fixation Tests; Connective Tissue; Cricetinae; Culture Techniques; Cytarabine; DNA, Viral; Embryo, Mammalian; Fluorescent Antibody Technique; gamma-Globulins; HeLa Cells; Humans; Immune Sera; Iodine Isotopes; Kidney; Laryngeal Neoplasms; Methods; Mouth Neoplasms; Neoplasms, Experimental | 1970 |
Identification of presumptive histone messenger RNA in rapidly labelled polysomal RNA of mouse myelomas.
Topics: Animals; Centrifugation, Density Gradient; Cytarabine; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Female; Histones; Isotope Labeling; Mice; Mice, Inbred BALB C; Multiple Myeloma; Neoplasms, Experimental; Plasmacytoma; Polyribosomes; RNA, Messenger; RNA, Ribosomal; Spectrophotometry, Ultraviolet; Time Factors; Tritium; Uridine | 1973 |
T antigens of bovine and canine adenoviruses demonstrated by immunofluorescence.
Topics: Adenoviridae; Animals; Antigens; Cattle; Cell Transformation, Neoplastic; Complement Fixation Tests; Culture Techniques; Cytarabine; Dogs; Embryo, Mammalian; Floxuridine; Fluorescent Antibody Technique; Kidney; Neoplasms, Experimental | 1969 |
Cell cycle phase specificity of antitumor agents.
Topics: Alkaloids; Alkylating Agents; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Carbazoles; Cell Line; Chlorambucil; Cricetinae; Cytarabine; Dactinomycin; Depression, Chemical; DNA; Fibroblasts; Floxuridine; In Vitro Techniques; Lung; Melphalan; Mitosis; Neoplasms, Experimental; Nitrosourea Compounds; Nucleosides; Protein Biosynthesis; RNA; Streptozocin; Thiosemicarbazones | 1972 |
Genetic and possible biochemical mechanisms in viral carcinogenesis.
Topics: Avian Sarcoma Viruses; Culture Techniques; Cytarabine; DNA; Floxuridine; Genetics; Methotrexate; Neoplasms, Experimental; Oncogenic Viruses; Radionuclide Imaging; RNA; Tritium | 1966 |
Studies on the transfer of subviral infectivity from SV40-induced hamster tumor cells to indicator cells.
Topics: Animals; Cricetinae; Culture Techniques; Cytarabine; Genes; Mice; Neoplasms, Experimental; Oncogenic Viruses; Parainfluenza Virus 1, Human; Radiation Effects; Simian virus 40; Tissue Extracts; Ultraviolet Rays | 1966 |
A comparative study of the antitumor and antiviral activity of 1-beta-D-arabinofuranosyl-5-fluorocytosine (FCA) and 1-beta-D-arabinofuranosylcytosine (CA).
Topics: Animals; Antineoplastic Agents; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Culture Techniques; Cytarabine; Cytosine; DNA Viruses; Enterovirus; Herpesviridae Infections; Leukemia L1210; Mammary Neoplasms, Experimental; Methods; Mice; Neoplasms, Experimental; Nucleosides; Orthomyxoviridae; Rabbits; Rats; RNA Viruses; Simplexvirus; Vaccinia virus | 1969 |
Deoxycytidine kinase. I. Distribution in normal and neoplastic tissues and interrelationships of deoxycytidine and 1-beta-D-arabinofuranosylcytosine phosphorylation.
Topics: Adenocarcinoma; Animals; Carcinoma, Hepatocellular; Cattle; Chick Embryo; Chromatography, Ion Exchange; Cytarabine; Cytosine Nucleotides; Deoxyuridine; Escherichia coli; Fibrosarcoma; Kinetics; Leukemia L1210; Leukemia, Experimental; Liver Neoplasms; Lymphoid Tissue; Mice; Mitosis; Neoplasms, Experimental; Nucleosides; Nucleotides; Phosphotransferases; Rats; Thymidine; Thymus Gland | 1969 |
Analysis of SV40-induced transformation of hamster kidney tissue in vitro. VI. Characteristics of mitomycin C induction.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Cytarabine; Embryo, Mammalian; Haplorhini; Humans; Interferons; Kidney; Lysogeny; Mice; Mitomycins; Mouth Mucosa; Neoplasms, Experimental; Simian virus 40; Virus Replication | 1969 |
Polynucleotide ligase activity in cells infected with simian virus 40, polyoma virus, or vaccinia virus.
Topics: Animals; Carbon Isotopes; Cell Line; Cell Nucleus; Chick Embryo; Cricetinae; Cytarabine; Cytoplasm; DNA Replication; DNA, Viral; Embryo, Mammalian; Fibroblasts; Haplorhini; HeLa Cells; Humans; Kidney; Ligases; Lymphoma; Mice; Neoplasms, Experimental; Polyomavirus; Puromycin; Rifampin; Simian virus 40; Thymoma; Vaccinia virus | 1969 |
Induction of SV40 transplantation antigen (TrAg) during the lytic cycle.
Topics: Animals; Animals, Newborn; Antigens; Bromodeoxyuridine; Cell Line; Cricetinae; Cycloheximide; Cytarabine; Cytopathogenic Effect, Viral; Dactinomycin; Female; Floxuridine; Fluorescent Antibody Technique; Haplorhini; Immune Tolerance; Immunity; Immunization; Kidney; Male; Neoplasms, Experimental; Neutralization Tests; Puromycin; Simian virus 40; Time Factors | 1970 |
Studies on nondefective adenovirus-simian virus 40 hybrid viruses. I. A newly characterized simian virus 40 antigen induced by the Ad2+ND 1 virus.
Topics: Adenoviridae; Animals; Antigens; Cattle; Cell Line; Cell Nucleus; Cell Transformation, Neoplastic; Cells, Cultured; Complement Fixation Tests; Cricetinae; Cytarabine; Fluorescent Antibody Technique; Genetics, Microbial; Guinea Pigs; Haplorhini; Hot Temperature; Humans; Hybridization, Genetic; Immune Sera; Kidney; Neoplasms, Experimental; Neutralization Tests; Simian virus 40 | 1971 |
Effect of chemotherapy and-or head irradiation on survival of mice with intracranial glioma.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Copper; Cytarabine; Disease Models, Animal; Ependymoma; Female; Glioblastoma; Hematoporphyrins; Male; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Nitroso Compounds; Nitrosourea Compounds; Porphyrins; Radiotherapy; Urea | 1971 |
Combination therapy: some concepts and results.
Topics: Animals; Antineoplastic Agents; Child; Cyclohexanes; Cyclophosphamide; Cytarabine; Dactinomycin; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Humans; Imidazoles; Leukemia L1210; Lung Neoplasms; Melanoma; Mice; Neoplasm Metastasis; Neoplasms; Neoplasms, Experimental; Nitrogen Mustard Compounds; Nitrosourea Compounds; Thioguanine; Triazenes; Wilms Tumor | 1974 |
Effect of inhibitors of nucleic acid synthesis on steroid-mediated induction of tyrosine aminotransferase in hepatoma cell cultures.
Topics: Carbon Isotopes; Culture Techniques; Cycloheximide; Cytarabine; Dactinomycin; Dexamethasone; DNA; Enzyme Induction; Mitomycins; Neoplasms, Experimental; RNA; Thymidine; Tritium; Tyrosine Transaminase; Uridine; Valine | 1967 |
The combined effect of drugs and tumor-specific antibodies in protection against a mouse lymphoma.
Topics: Animals; Antibodies, Neoplasm; Chlorambucil; Cytarabine; Immune Sera; Immunotherapy; Lymphoma; Melphalan; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Rabbits; Time Factors | 1974 |
Enhancement of the cancer chemotherapeutic effect of the cell cycle phase specific agents methotrexate and cytosine arabinoside when given as a water-oil-water emulsion.
Topics: Animals; Carcinoma 256, Walker; Cytarabine; Emulsions; Lymphoma; Methotrexate; Mice; Neoplasms, Experimental; Squalene; Time Factors; Water | 1974 |
Manipulation of DNA synthesis in normal and neoplastic tissues with drugs.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Carcinoma, Ehrlich Tumor; Cell Line; Cytarabine; Deoxyribonucleosides; DNA; DNA, Neoplasm; Female; Mice; Neoplasms, Experimental; Thioguanine; Time Factors; Vidarabine | 1974 |
The experimental antitumour properties of three congeners of the acridylmethanesulphonanilide (AMSA) series.
Topics: Acridines; Animals; Anisoles; Antineoplastic Agents; Chemical Phenomena; Chemistry, Physical; Cytarabine; Dose-Response Relationship, Drug; Injections, Intradermal; Injections, Intraperitoneal; Injections, Intravenous; Injections, Subcutaneous; Leukemia L1210; Leukemia, Experimental; Mammary Neoplasms, Experimental; Melanoma; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Phenylenediamines; Skin Neoplasms; Structure-Activity Relationship; Sulfones | 1974 |
Combination chemotherapy for spontaneous AKR lymphoma.
Topics: Animals; Antineoplastic Agents; Biological Assay; Carmustine; Cyclohexanes; Cyclophosphamide; Cytarabine; Disease Models, Animal; Doxorubicin; Drug Therapy, Combination; Lymphoma; Methotrexate; Mice; Mice, Inbred AKR; Neoplasms, Experimental; Nitrosourea Compounds; Organ Size; Palmitic Acids; Prednisone; Remission, Spontaneous; Rodent Diseases; Spleen; Splenomegaly; Thymus Gland; Time Factors; Vincristine | 1974 |
Approaches to combination chemotherapy in rat, mouse, and hamster tumors.
Topics: Adenocarcinoma; Amides; Androstanols; Animals; Antineoplastic Agents; Cricetinae; Cyclohexanes; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Therapy, Combination; Estradiol; Female; Hydroxyurea; Imidazoles; Mammary Neoplasms, Experimental; Melanoma; Melphalan; Mice; Mice, Inbred C3H; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Osteosarcoma; Plasmacytoma; Progesterone; Rats; Sarcoma, Experimental; Triazenes | 1974 |
Pharmacology of 3,5-diamino-1,24-triazole (guanazole). 1. Antitumor activity of guanazole.
Topics: Amines; Animals; Antineoplastic Agents; Carcinoma 256, Walker; Cyclophosphamide; Cytarabine; Depression, Chemical; Female; Hydroxyurea; In Vitro Techniques; Leukemia L1210; Leukemia, Experimental; Lymphoma, Large B-Cell, Diffuse; Male; Mast-Cell Sarcoma; Methotrexate; Mice; Neoplasms, Experimental; Nitrosourea Compounds; Plasmacytoma; Structure-Activity Relationship; Triazoles | 1972 |
Characterization of protein and DNA in P815 cells sensitive and resistant to 1- -D-arabinofuranosylcytosine.
Topics: Animals; Carbon Isotopes; Cell Line; Cytarabine; DNA, Neoplasm; Drug Resistance; Electrophoresis, Disc; Immunodiffusion; In Vitro Techniques; Mice; Neoplasm Proteins; Neoplasms, Experimental; Nucleic Acid Hybridization; Phosphotransferases; Tritium | 1972 |
Effects of inhibitors of protein and nucleic acid synthesis on the expression of H-2 and Moloney leukemia virus-determined cell-surface antigens on cultured murine lymphoma cells.
Topics: Animals; Antigens; Antigens, Neoplasm; Antigens, Viral; Antineoplastic Agents; Cell Membrane; Cells, Cultured; Culture Media; Cycloheximide; Cytarabine; Dactinomycin; Histocompatibility Antigens; Hydroxyurea; Lymphoma; Mice; Mitomycins; Moloney murine leukemia virus; Neoplasm Proteins; Neoplasms, Experimental; Puromycin; RNA, Neoplasm | 1972 |
Scheduling of arabinosylcytosine and 6-thioguanine therapy.
Topics: Animals; Bone Marrow; Cells, Cultured; Chromatography, Paper; Cytarabine; DNA; Female; Half-Life; Leukemia L1210; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Nucleotides; Sulfur Isotopes; Thioguanine; Time Factors | 1973 |
Cell-kill kinetics of several S-phase-specific drugs.
Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Division; Cell Line; Cell Survival; Cricetinae; Cytarabine; DNA, Neoplasm; Formates; Hydroxyurea; Kinetics; Leukemia L1210; Lung; Mice; Neoplasms, Experimental; Pyridines; Thiosemicarbazones; Time Factors | 1973 |
Inhibition of replication and differentiation in malignant mouse neuroblasts.
Topics: Amino Acids; Animals; Cell Differentiation; Cell Division; Cell Line; Cell Survival; Cytarabine; DNA Replication; Methotrexate; Mice; Microscopy, Electron; Neoplasm Proteins; Neoplasms, Experimental; Neuroblastoma; RNA; Thymidine; Tritium; Uridine | 1973 |
Multiple emulsions, a suitable vehicle to provide sustained release of cancer chemotherapeutic agents.
Topics: Animals; Antineoplastic Agents; Cytarabine; Delayed-Action Preparations; Diarrhea; Emulsions; Lymphoma; Methotrexate; Mice; Neoplasms, Experimental; Pharmaceutical Vehicles; Rats; Vinblastine; Vomiting | 1972 |
Chemotherapy of the transplanted KHT fibrosarcoma in mice.
Topics: Animals; Antineoplastic Agents; Biological Assay; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cyclophosphamide; Cytarabine; Drug Synergism; Female; Fibrosarcoma; Hematopoietic Stem Cells; Lung Neoplasms; Methotrexate; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosourea Compounds; Ultracentrifugation; Vinblastine | 1972 |
Antitumor activity of cyclocytidine in a variety of tumors.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cell Line; Cyclization; Cyclophosphamide; Cytarabine; Cytidine; Dose-Response Relationship, Drug; Female; Fluorouracil; Leukemia L1210; Leukemia, Experimental; Male; Mercaptopurine; Methotrexate; Mice; Mitomycins; Neoplasms, Experimental; Sarcoma 180 | 1972 |
The effect of chemotherapeutic agents on the incorporation of DNA precursors by experimental brain tumors.
Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Bone Marrow; Brain; Brain Neoplasms; Carbon Isotopes; Carmustine; Cyclohexanes; Cytarabine; Deoxyuridine; Disease Models, Animal; DNA, Neoplasm; Dose-Response Relationship, Drug; Ependymoma; Glioma; Lymph Nodes; Male; Methotrexate; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosourea Compounds; Thymidine; Tritium | 1972 |
In vivo synchrony of solid B16 melanoma by cytosine arabinoside, an inhibitor of DNA synthesis.
Topics: Animals; Autoradiography; Cell Division; Cell Survival; Cytarabine; DNA; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Male; Melanoma; Mice; Mice, Inbred C57BL; Mitosis; Neoplasm Transplantation; Neoplasms, Experimental; Thymidine; Time Factors; Transplantation, Homologous; Tritium | 1972 |
Studies on the effects of hydroxyurea and other anticancer drugs upon pyrimidine metabolism.
Topics: Amidohydrolases; Animals; Antineoplastic Agents; Ascites; Carbon Isotopes; Cyclophosphamide; Cytarabine; Deoxyuridine; DNA; Fluorouracil; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Leukocytes; Methotrexate; Mice; Neoplasms, Experimental; Orotic Acid; Pyrimidines; Transferases; Triazines | 1969 |
Synthesis of 1-beta-L-arabinofuranosylcytosine, the enantiomer of cytosine arabinoside.
Topics: Animals; Cytarabine; Furans; Leukemia L1210; Neoplasms, Experimental; Osteosarcoma; Stereoisomerism | 1971 |
Effect of combined therapy with cytosine arabinoside (NSC-63878) and l,3-bis-(2-chloroethyl)-1-nitrosourea (NSC-409962) on sarcoma 180 and L1210 in vivo.
Topics: Animals; Cytarabine; DNA, Neoplasm; Drug Synergism; Female; Leukemia L1210; Mice; Neoplasms, Experimental; Nitroso Compounds; Sarcoma, Experimental; Thymidine; Time Factors; Tritium; Urea | 1969 |
Radiopotentiating action of 1-beta-D-arabinofuranosylcytosine in a xenografted human colonic carcinoma.
Topics: Animals; Cheek; Colonic Neoplasms; Cricetinae; Cytarabine; Humans; Neoplasms, Experimental; Radiation-Sensitizing Agents | 1970 |
Reduction of colony-forming cell sensitivity to arabinosylcytosine by halothane anesthesia.
Topics: Anesthesia, Inhalation; Animals; Bone Marrow; Bone Marrow Cells; Cell Division; Cytarabine; Drug Synergism; Female; Halothane; Lymphoma; Mice; Neoplasms, Experimental; Nitrous Oxide; Splenic Neoplasms; Vinblastine | 1970 |
Altered sensitivity of a hamster plasmacytoma to cytosine arabinoside (NSC-63878).
Topics: Animals; Antineoplastic Agents; Cell Survival; Cricetinae; Cyclophosphamide; Cytarabine; Neoplasm Transplantation; Neoplasms, Experimental; Plasmacytoma; Thymidine; Time Factors | 1970 |
Studies on drug resistance. II. Kinase patterns in P815 neoplasms sensitive and resistant to 1-beta-D-arabinofuranosylcytosine.
Topics: Animals; Cell Line; Culture Techniques; Cytarabine; Mice; Neoplasms, Experimental; Nucleotidases; Phosphotransferases; Tritium | 1970 |
[Recent acquisitions in the metabolism, mechanism of action and toxicity of cytarabine].
Topics: Animals; Cytarabine; Dogs; Mice; Neoplasms, Experimental; Rats | 1971 |
Radiosensitization of bacteria by 1-beta-D-arabinofuranosylcytosine (NSC-63878).
Topics: Cytarabine; Micrococcus; Neoplasms, Experimental; Radiation Effects | 1967 |
Viruses and renal carcinoma of Rana pipiens. VI. Interrelationships of macromolecular synthesis and infectious virus production in frog virus 3-infected BHK 21/13 cells.
Topics: Adenine; Animals; Anura; Carbon Isotopes; Culture Techniques; Cycloheximide; Cytarabine; Dactinomycin; DNA; DNA, Viral; Herpesviridae; Hydroxyurea; Idoxuridine; Inclusion Bodies, Viral; Kidney Neoplasms; Leucine; Neoplasms, Experimental; Oncogenic Viruses; Protein Biosynthesis; RNA; RNA, Viral; Thymidine; Tritium; Uridine; Viral Proteins; Virus Replication | 1968 |
Peroral therapy with cytosine arabinoside. Preliminary laboratory and clinical findings.
Topics: Aged; Animals; Bone Marrow; Colonic Neoplasms; Cricetinae; Cytarabine; Esophageal Neoplasms; Humans; Leukemia L1210; Male; Middle Aged; Neoplasms, Experimental; Rectal Neoplasms; Stomach Neoplasms | 1968 |
Inhibition of tumor induction in two-stage carcinogenesis on mouse skin.
Topics: Aflatoxins; Animals; Antineoplastic Agents; Benz(a)Anthracenes; Chloroquine; Cyclohexanes; Cytarabine; Dactinomycin; Ethers, Cyclic; Female; Mice; Neoplasms, Experimental; Skin Neoplasms; Uracil | 1969 |
Relation of thymidine index to pulmonary tumor response in mice receiving urethan and other carcinogens.
Topics: Animals; Autoradiography; Carbamates; Carcinogens; Cytarabine; Dactinomycin; DNA; Fluorouracil; Injections, Intraperitoneal; Injections, Subcutaneous; Lung; Lung Neoplasms; Male; Mechlorethamine; Methylcholanthrene; Mice; Neoplasms, Experimental; Puromycin; Thymidine; Tritium; Urethane | 1969 |
Requirements for RNA and DNA synthesis in the transformation of mouse embryo cells by murine sarcoma virus (Moloney).
Topics: Cell Line; Cell Transformation, Neoplastic; Culture Techniques; Cytarabine; Dactinomycin; DNA; Embryo, Mammalian; Embryo, Nonmammalian; Mitomycins; Moloney murine leukemia virus; Neoplasms, Experimental; RNA; Thymidine; Tritium; Uridine; Virus Replication | 1969 |
Studies on drug resistance. I. Distribution of l-beta-D-arabinofuranosylcytosine, cytidine and deoxycytidine in mice bearing ara-C-sensitive and-resistant P815 neoplasms.
Topics: Animals; Brain Chemistry; Chromatography, Paper; Cytarabine; Drug Resistance, Microbial; Kidney; Liver; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Nucleosides; Oxidoreductases; Phosphotransferases; Tritium | 1969 |
Activity of cytosine arabinoside (NSC-63878) in a spectrum of rodent tumors.
Topics: Animals; Cytarabine; In Vitro Techniques; Leukemia, Experimental; Mice; Neoplasms, Experimental; Rats | 1965 |
Antitumor activity and pharmacologic disposition of cytosine arabinoside (NSC-63878).
Topics: Animals; Antineoplastic Agents; Cytarabine; Dogs; Female; Male; Mice; Neoplasms, Experimental; Rats; Tritium | 1965 |