cytarabine and Experimental Leukemia

cytarabine has been researched along with Experimental Leukemia in 173 studies

Research

Studies (173)

TimeframeStudies, this research(%)All Research%
pre-1990141 (81.50)18.7374
1990's24 (13.87)18.2507
2000's6 (3.47)29.6817
2010's2 (1.16)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bentrude, WG; Beres, J; Kruppa, G; McKernan, PA; Robins, RK1
Dias, CB; Hansch, C; Khwaja, TA; Pentecost, S; Selassie, CD1
Chu, CK; Fox, JJ; Hollenberg, DH; Reichman, U; Watanabe, KA1
Baker, SD; Buelow, DR; Cotton, A; Dang, J; Drenberg, CD; Fu, Q; Gruber, TA; Guy, RK; Hu, S; Inaba, H; Jeon, JY; Li, M; Orwick, SJ; Pioso, M; Ribeiro, RC; Rubnitz, JE; Shelat, A1
Kataoka, K; Koya, J; Kurokawa, M; Morita, K; Nakazaki, K; Sato, T; Sumitomo, Y; Tsuruta-Kishino, T1
Bridger, G; DiPersio, JF; Holt, MS; Ley, TJ; Nervi, B; Piwnica-Worms, D; Prior, JL; Ramirez, P; Rettig, MP; Ritchey, JK; Uy, GL1
Barbeau, S; Bouffard, DY; Gourdeau, H; Hamelin, B; Jolivet, J; Leblond, L; Ouellet, F; Richard, A1
CHU, MY; FISCHER, GA4
BOSTWICK, L; EVANS, JS; MENGEL, GD1
EVANS, JS; MENGEL, GD1
BOSTWICK, L; EVANS, JS; MENGEL, GD; MUSSER, EA1
Cano, F; Follows, GA; Pannel, R; Rabbitts, TH1
Hall, TC; Kessel, D; Wodinsky, I1
Buskirk, HH; Lummis, WL; Smith, CG1
Imamishi, J; Tanaka, A1
Chechik, BE; Gelfand, EW; Letarte, M; Mak, TW; Nagasawa, K; Sengupta, S1
Damin, LA; Graham, J; Kreis, W1
Lee, SH; Sartorelli, AC1
Gotlib, VIa; Pelevina, II1
Beck, WT; Conter, V1
Kuliczkowski, K; Preisler, HD; Raza, A; Weidong, G1
Burke, PJ; Vaughan, WP1
Boyd, A; Cheng, ZM; Leyden, M; Manoharan, A; Sullivan, J1
Arlett, CF; Cole, J; Green, MH; Lowe, J; Muriel, W1
Hayashi, M; Honma, Y; Hozumi, M; Okabe-Kado, J; Tsuruo, T1
Ambaye, RY; Gokhale, SV; Parchure, M1
Burke, PJ; Karp, JE; Vaughan, WP2
Howell, SB; Streifel, JA1
Reusch, K; Schmähl, D; Zeller, WJ1
Capizzi, RL; Morgenstern, B; Schwartz, SA1
Burchenal, JH; Chou, TC; Fox, JJ; Lokys, L; Smith, RS; Su, TL; Watanabe, KA1
Braun, TJ; Burchenal, JH; Chou, TC; Fox, JJ; Philips, FS; Schmid, FA; Su, TL; Watanabe, KA1
Burke, PJ; Karp, JE; Sanford, PL; Vaughan, WP1
Colly, LP; van Bekkum, DW1
Epstein, J; Preisler, H1
Ross, DW1
Schmähl, D; Zeller, WJ2
Arlett, CF; Burns, VW; Hill, R; Lehmann, AR; Rogers, AM1
Preisler, HD1
Barkhotkina, MF; Bukhman, VM1
Iida, H; Naganuma, K; Tsukagoshi, S; Tsuruo, T1
Honders, WH; Landegent, JE; Ruiz van Haperen, VW; Stegmann, AP; Willemze, R1
Honders, MW; Landegent, JE; Stegmann, AP; Willemze, R1
De Traversay, J; Jean, Y; Lemieux, P1
Cope, FO; Feuers, RJ; Scheving, LA; Scheving, LE; Tsai, TH1
Buckingham, L; Coon, JS; Holian, O; Komarov, PG; Mechetner, EB; Roninson, IB; Shtil, AA; Tee, L1
Balzarini, J; Breistøl, K; De Clercq, E; Fodstad, O; Martinsen, M; Myhren, F; Sandvold, ML1
El-Beltagi, HM; Hagenbeek, A; Martens, AC1
Korycka, A; Lech-Maranda, E; Robak, T1
Dutcher, JA; Ge, Y; Huang, X; Matherly, LH; Mohammad, RM; Ravindranath, Y; Stout, ML; Taub, JW1
Karon, M; Lee, T; Monparler, RL1
Bocaccino, CA; Greenberger, JS; Moloney, WC; Szot, SJ1
Igarashi, T; Kishimoto, T; Okada, M; Yamamura, Y1
Burchenal, JH; Chisholm, J; Kalaher, K; O'Toole, T1
Egan, EM; Ensminger, WD; Greenberger, JS; Moloney, WC; Muse, MB1
Chu, MY; Raetz, CR; Srivastava, S; Turcotte, JG1
Bekesi, JG; Holland, JF1
Rustum, YM1
Chabner, BA; Hande, KR1
Lauzon, GJ; Paran, JH; Paterson, AR1
Belch, AW; Lauzon, GJ; Paterson, AR1
Aglietta, M; Colly, L1
Burke, PJ; Jung, J; Vaughn, WP1
Chou, TC; Clarkson, BD; Ferguson, R; Fried, J; Kitahara, T; Oyama, A; Strife, A; Sullivan, S1
Cheng, YC; Creaven, P; Mihich, E; Pavelic, Z; Rustum, Y1
Kornacka, L; Malec, J; Sawecka, J1
Kim, M; Perry, S; Woo, KB1
Hoshi, A; Kuretani, K; Yoshida, M1
Lloyd, HH; Schabel, FM; Skipper, HE1
Kataoka, T; Kobayashi, T; Sakurai, Y; Tsukagoshi, S1
Fey, F; Ring, G1
Gavosto, F; Masera, P; Pagliardi, GL1
Burchenal, JH; Currie, VE; Dowling, MD; Fox, JJ; Krakoff, IH1
Mihich, E1
Burchenal, JH1
Ivankovic, S; Schmähl, D; Zeller, WJ1
Sakurai, Y1
Harrap, KR; Mulder, JH1
Atassi, G; Schaus, C; Tagnon, HJ1
Avery, T; Rivera, G; Roberts, DW1
Hoshi, A; Ichino, M; Kanai, T; Kuretani, K; Yoshida, M1
Barra, Y; Cano, JP; Carcassonne, Y; Riva, C; Rustum, Y1
Lotem, J; Sachs, L3
Suzuki, H1
Chou, TC; Kong, XB; Tong, WP1
Kristensen, J; Larsson, R; Nygren, P; Sandberg, C1
Brach, MA; Herrmann, F; Kharbanda, SM; Kufe, DW1
Datta, R; Kharbanda, S; Kufe, DW1
Nakamura, T; Uchida, M; Ueda, T1
Bhandal, AK; Carter, DL; Moore, DC; Studzinski, GP1
Boise, L; Grant, S; Howe, C; McCrady, C; Pettit, GR; Turner, A; Westin, E1
Bouffard, DY; Momparler, LF; Momparler, RL1
Hindahl, M; Hussein, AM; Jimenez, JJ; Yunis, AA1
Ben-Ishay, Z; Prindull, G; Sharon, S1
Amagasaki, T; Green, R; Jacobsen, DW1
Hussein, AM; Jimenez, JJ; McCall, CA; Yunis, AA1
Arentsen-Honders, W; Colly, LP; Edelbroek, PM; Richel, DJ; Starrenburg, IW; Willemze, R1
Bianchi-Scarră, G; Capra, V; Fiorentini, P; Garrĕ, C; Ravazzolo, R1
Capizzi, RL; White, JC; Yang, JL1
Iwabuchi, M; Takahashi, K1
Chitnis, MP; Deshpande, SS; Satyamoorthy, K1
Arnon, R; Hurwitz, E; Kashi, R; Sela, M; Wilchek, M1
Higashigawa, M; Hori, H; Kamiya, H; Kawasaki, H; Nobori, T; Ochiai, H; Ohkubo, T; Sakurai, M1
Capizzi, RL; Chandrasekaran, B; Dimling, J; Kute, TE; Morgan, T1
Hamazaki, M; Higashigawa, M; Ido, M; Kamiya, H; Kawasaki, H; Ohkubo, T; Sakurai, M; Taniguchi, K1
Capizzi, RL; Daniel, LW; King, L; Waite, M; Yang, JL1
Bolognesi, DP; Buckheit, RW; Weinhold, KJ1
Dontje, BH; Kroon, AM; Van den Bogert, C1
Boullier, BA; McKenna, PG1
Al-Ansari, HM; Farkas, WR; Walden, TL1
Jekunen, A1
Honma, Y; Hozumi, M; Kasukabe, T; Nishii, Y; Suda, T1
Colly, LP; Hagenbeek, A; Martens, AC1
Burke, PJ; Karp, JE; Saylor, PL1
Ishikura, H; Izumi, Y; Mochizuki, T; Okazaki, T; Sawada, H; Tashima, M; Uchino, H1
Cassileth, PA; Gale, RP1
Buchheit, DJ; Hong, CI; Kirisits, AJ; Nechaev, A; West, CR1
Harrison, SD; O'Dwyer, PJ; Trader, MW1
Ben-Ishay, Z; Borenstein, A; Prindull, G; Sharon, S1
Hoshino, A; Ito, Y; Machida, S1
Capizzi, RL; Cheng, EH; Cheng, YC; Kute, T; Yang, JL1
Bierling, R1
Aoshima, M; Sakurai, Y1
Burchenal, JH; Dowling, MD; Tan, CT1
Cihák, A; Veselỳ, J1
Furusawa, M; Ikawa, Y; Kawaguchi, T; Sugano, H1
Chu, MY; Fischer, GA; Momparler, RL1
Chu, MY; Hoovis, ML2
Gang, M; Kline, I; Tyrer, DD; Venditti, JM; Waravdekar, VS1
Durham, JP; Ives, DH1
Schabel, FM; Skipper, HE1
Capizzi, RL; Nahas, A1
Atwell, GJ; Cain, BF1
Amiel, JL; De Vassal, F; Hayat, M; Jasmin, C; Mathé, G; Pouillart, P; Rappaport, H; Rosenfeld, C; Schneider, M; Schwarzenberg, L; Weiner, R1
Handschumacher, RE; Summers, WP1
Frei, E; Goldin, A; Schabel, FM1
Bodey, GP; Frei, E; Freireich, E; Ho, DH1
Cardoso, SS; Good, RA; Halberg, F; Haus, E; Kühl, JF; Lee, JK; Pauly, JE; Rosene, G; Runge, W; Scheving, LE; Shiotsuka, R; Spalding, JF1
Adamson, RH; Hahn, MA1
Glynn, JP; Goldberg, AI; Goldin, A; Kende, M; Mantel, N1
Avery, TL; Roberts, D1
Burchenal, JH; Giner-Sorolla, A; Longley-Cook, J; McCravey, M1
Omine, M; Perry, S1
Hoshi, A; Ichino, M; Kanai, T; Kanzawa, F; Kuretani, K1
Hoshi, A; Kanai, T; Kanazawa, F; Kikugawa, K; Kuretani, K1
Omine, M; Perry, S; Sarna, GP1
Kensler, CJ; Swiniarski, J; Venditti, JM; Wodinsky, I1
Clarkson, BD; Fried, J1
Frei, E; Goldin, A; Henderson, ES; Holland, JF; Newman, JW; Sandberg, JS1
Chirigos, MA1
Cain, BF2
Hutchison, DJ; Schmid, FA2
Lamerton, LF1
Hoshi, A; Kanzawa, F; Kuretani, K1
Chu, MY1
Fischer, GA1
Benvenisti, D; Burchenal, JH; Dollinger, M1
Laster, WR; Schabel, FM; Skipper, HE; Trader, MW1
Inagaki, A; Nakamura, T; Wakisaka, G1
Goldin, A; Schrecker, AW1
Zeleznick, LD1
Kensler, CJ; Wodinsky, I1
Adams, HH; Burchenal, JH; Fox, JJ; Newell, NS1

Reviews

10 review(s) available for cytarabine and Experimental Leukemia

ArticleYear
Duration of the dormant state in an established cell line of human hematopoietic cells.
    Cancer research, 1977, Volume: 37, Issue:12

    Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Division; Cell Line; Cell Survival; Clone Cells; Cytarabine; Demecolcine; Drug Resistance; Humans; Interphase; Kinetics; Leukemia, Experimental; Thymidine

1977
Murine and human leukemias.
    Bibliotheca haematologica, 1975, Issue:40

    Topics: Animals; Antineoplastic Agents; Asparaginase; Cyclophosphamide; Cytarabine; Drug Evaluation, Preclinical; Drug Resistance; Leukemia L1210; Leukemia, Experimental; Mercaptopurine; Methotrexate; Mice; Mice, Inbred AKR; Prednisone; Vincristine

1975
[Cell differentiation induction therapy in leukemia].
    Nihon rinsho. Japanese journal of clinical medicine, 1986, Volume: 44, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Cell Differentiation; Cell Division; Cell Line; Cytarabine; Humans; Leukemia; Leukemia, Experimental; Tretinoin

1986
Amsacrine: a review.
    Leukemia research, 1986, Volume: 10, Issue:11

    Topics: Amsacrine; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Evaluation; Drug Resistance; Humans; Leukemia, Experimental; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma

1986
Treatment of acute lymphoblastic leukemia.
    Annual review of medicine, 1972, Volume: 23

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Animals; Antineoplastic Agents; Asparaginase; Central Nervous System Diseases; Child; Cyclophosphamide; Cytarabine; Cytopathogenic Effect, Viral; Daunorubicin; Humans; Kinetics; Leukemia, Experimental; Leukemia, Lymphoid; Meninges; Mercaptopurine; Methotrexate; Mice; Oncogenic Viruses; Patient Care Team; Remission, Spontaneous; Reverse Transcriptase Inhibitors; RNA Viruses; RNA-Directed DNA Polymerase; Time Factors; Vincristine

1972
Resistance of mammalian tumour cells toward pyrimidine analogues. A review.
    Oncology, 1973, Volume: 28, Issue:3

    Topics: Animals; Antimetabolites; Azacitidine; Azauridine; Bromouracil; Carcinoma, Ehrlich Tumor; Cell Line; Cricetinae; Cytarabine; Deoxycytidine; Drug Resistance; Fluorouracil; Genetic Code; Leukemia, Experimental; Leukemia, Lymphoid; Mast-Cell Sarcoma; Mice; Mutation; Neoplasms, Experimental; Oncogenic Viruses; Phosphotransferases; Pyrimidines; Sarcoma, Experimental; Selection, Genetic; Thymidine Kinase; Uracil; Virus Replication

1973
Toward a chronotherapy of neoplasia: tolerance of treatment depends upon host rhythms.
    Experientia, 1973, Aug-15, Volume: 29, Issue:8

    Topics: Animals; Antineoplastic Agents; Bone Marrow Cells; Circadian Rhythm; Cytarabine; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Tolerance; Duodenum; Female; Humans; Infant, Newborn; Leukemia, Experimental; Leukocytes; Liver; Mice; Mitosis; Models, Biological; Neoplasms; Pancreas; Radiation Injuries, Experimental; Rats; Skin

1973
Changing concepts of treatment in acute leukemia.
    The Medical clinics of North America, 1971, Volume: 55, Issue:3

    Topics: Acute Disease; Animals; Antineoplastic Agents; Asparaginase; Cell Differentiation; Cell Division; Cytarabine; DNA; Erythropoiesis; Hematopoiesis; Humans; Immunosuppressive Agents; Kinetics; Leukemia; Leukemia, Experimental; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mice; Mitosis; Models, Biological; Oncogenic Viruses; Prednisone; Remission, Spontaneous; Time Factors

1971
The chemotherapy of human and animal acute leukemia.
    Cancer chemotherapy reports, 1971, Volume: 55, Issue:4

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Asparaginase; Azaserine; Cell Division; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Disease Models, Animal; Drug Combinations; Humans; Kinetics; Leukemia L1210; Leukemia, Experimental; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Neoplasms; Prednisone; Remission, Spontaneous; RNA, Neoplasm; Vincristine

1971
Experimental cancer chemotherapy: strategy for cure.
    The New Zealand medical journal, 1971, Volume: 73, Issue:465

    Topics: Alkylating Agents; Animals; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Half-Life; Haplorhini; Leukemia, Experimental; Mercaptopurine; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Transplantation, Homologous

1971

Trials

4 trial(s) available for cytarabine and Experimental Leukemia

ArticleYear
Active immunotherapy in leukemia with neuraminidase-modified leukemic cells.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1977, Issue:62

    Topics: Animals; Antigens, Neoplasm; Clinical Trials as Topic; Cytarabine; Daunorubicin; Humans; Hypersensitivity, Delayed; Immunization; Immunotherapy; Leukemia Virus, Murine; Leukemia, Experimental; Leukemia, Myeloid, Acute; Mice; Mice, Inbred AKR; Mice, Inbred C57BL; Mice, Inbred DBA; Neuraminidase; Tumor Virus Infections

1977
Design of adjuvant chemotherapy based on target cell determinants of drug action: possibilities and limitations.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1979, Volume: 67

    Topics: Animals; Antineoplastic Agents; Clinical Trials as Topic; Cytarabine; Drug Evaluation; Humans; Leukemia, Experimental; Leukemia, Myeloid, Acute; Mice; Neoplasms; Research Design

1979
Amsacrine: a review.
    Leukemia research, 1986, Volume: 10, Issue:11

    Topics: Amsacrine; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Evaluation; Drug Resistance; Humans; Leukemia, Experimental; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma

1986
The chemotherapy of human and animal acute leukemia.
    Cancer chemotherapy reports, 1971, Volume: 55, Issue:4

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Asparaginase; Azaserine; Cell Division; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Disease Models, Animal; Drug Combinations; Humans; Kinetics; Leukemia L1210; Leukemia, Experimental; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Neoplasms; Prednisone; Remission, Spontaneous; RNA, Neoplasm; Vincristine

1971

Other Studies

161 other study(ies) available for cytarabine and Experimental Leukemia

ArticleYear
Synthesis and antitumor and antiviral activities of a series of 1-beta-D-ribofuranosyl-5-halocytosine (5-halocytidine) cyclic 3',5'-monophosphates.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:4

    Topics: Animals; Antineoplastic Agents; Antiviral Agents; Cyclic CMP; Cytosine Nucleotides; Leukemia, Experimental; Mice; Protein Kinases

1985
Comparative structure-activity relationships of antifolate triazines inhibiting murine tumor cells sensitive and resistant to methotrexate.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:3

    Topics: Animals; Chemical Phenomena; Chemistry, Physical; Chickens; Drug Resistance; Folic Acid Antagonists; Humans; Leukemia L5178; Leukemia, Experimental; Mathematics; Methotrexate; Mice; Structure-Activity Relationship; Triazines

1984
Nucleosides. 116. 1-(beta-D-Xylofuranosyl)-5-fluorocytosines with a leaving group on the 3' position. Potential double-barreled masked precursors of anticancer nucleosides.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:10

    Topics: Animals; Antineoplastic Agents; Cell Line; Cytosine Nucleotides; Leukemia, Experimental; Mice; Structure-Activity Relationship

1980
A high-throughput screen indicates gemcitabine and JAK inhibitors may be useful for treating pediatric AML.
    Nature communications, 2019, 05-16, Volume: 10, Issue:1

    Topics: Adult; Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transplantation; Cell Line, Tumor; Child; Child, Preschool; Cytarabine; Deoxycytidine; Disease-Free Survival; Female; Gemcitabine; High-Throughput Screening Assays; Humans; Infant; Janus Kinase Inhibitors; Leukemia, Experimental; Leukemia, Myeloid, Acute; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Taxoids; Whole-Body Irradiation; Xenograft Model Antitumor Assays; Young Adult

2019
Cytoprotective autophagy maintains leukemia-initiating cells in murine myeloid leukemia.
    Blood, 2016, 09-22, Volume: 128, Issue:12

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Autophagy; Autophagy-Related Protein 5; Autophagy-Related Protein 7; Cytarabine; Leukemia, Experimental; Leukemia, Myeloid, Acute; Mice; Mice, Inbred C57BL; Mice, Knockout; Neoplastic Stem Cells; Signal Transduction

2016
Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100.
    Blood, 2009, Jun-11, Volume: 113, Issue:24

    Topics: Animals; Anti-HIV Agents; Antimetabolites, Antineoplastic; Apoptosis; Benzylamines; Bone Marrow; Cathepsin G; Cathepsins; Colony-Forming Units Assay; Cyclams; Cytarabine; Drug Synergism; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cells; Heterocyclic Compounds; Leukemia, Experimental; Leukemia, Promyelocytic, Acute; Mice; Mice, Inbred C57BL; Protein Transport; Receptors, CXCR4; Serine Endopeptidases; Stromal Cells; Tumor Cells, Cultured

2009
Complementary antineoplastic activity of the cytosine nucleoside analogues troxacitabine (Troxatyl) and cytarabine in human leukemia cells.
    Cancer chemotherapy and pharmacology, 2003, Volume: 52, Issue:6

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biological Transport; Cell Line, Tumor; Cell Survival; Cytarabine; Cytosine; Dioxolanes; DNA, Neoplasm; Female; Humans; Inhibitory Concentration 50; Injections, Intraperitoneal; Leukemia, Experimental; Mice; Mice, SCID; Neoplasm Transplantation

2003
A proposed mechanism of action of 1-beta-D-arabinofuranosyl-cytosine as an inhibitor of the growth of leukemic cells.
    Biochemical pharmacology, 1962, Volume: 11

    Topics: Animals; Antineoplastic Agents; Cytarabine; Cytosine; Leukemia, Experimental; Nucleosides; Nucleotides

1962
SYNERGISM OF THE ANTINEOPLASTIC ACTIVITY OF CYTOSINE ARABINOSIDE BY PORFIROMYCIN.
    Biochemical pharmacology, 1964, Volume: 13

    Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Body Weight; Cytarabine; Cytosine; Leukemia; Leukemia L1210; Leukemia, Experimental; Mice; Mitomycin; Mitomycins; Neoplasms; Neoplasms, Experimental; Nucleosides; Pharmacology; Porfiromycin; Research; Survival

1964
THE REVERSAL OF CYTOSINE ARABINOSIDE ACTIVITY IN VIVO BY DEOXYCYTIDINE.
    Biochemical pharmacology, 1964, Volume: 13

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cytarabine; Cytosine; Deoxycytidine; Leukemia; Leukemia, Experimental; Neoplasms; Neoplasms, Experimental; Nucleosides; Pharmacology; Research; Sarcoma 180

1964
THE EFFECT OF 1-BETA-D-ARABINOFURANOSYLCYTOSINE HYDROCHLORIDE ON MURINE NEOPLASMS.
    Cancer research, 1964, Volume: 24

    Topics: Animals; Anti-Bacterial Agents; Antibodies; Antineoplastic Agents; Blood Cells; Carcinoma, Ehrlich Tumor; Cortisone; Cytarabine; Cytosine; Leukemia L1210; Leukemia, Experimental; Lymphoma; Mercaptopurine; Methotrexate; Mice; Neoplasms; Neoplasms, Experimental; Pharmacology; Research; Sarcoma 180

1964
COMPARATIVE STUDIES OF LEUKEMIC CELLS SENSITIVE AND RESISTANT TO CYTOSINE ARABINOSIDE.
    Biochemical pharmacology, 1965, Volume: 14

    Topics: Adenosine Triphosphate; Antineoplastic Agents; Chromatography; Cytarabine; Cytosine; DNA; DNA, Neoplasm; Leukemia; Leukemia, Experimental; Magnesium; Neoplasms; Nucleosides; Pharmacology; Phosphotransferases; Research; RNA; RNA, Neoplasm; Tissue Culture Techniques

1965
Preclinical modeling of cytosine arabinoside response in Mll-Enl translocator mouse leukemias.
    Molecular cancer therapeutics, 2008, Volume: 7, Issue:3

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cytarabine; Leukemia, Experimental; Mice; Models, Theoretical; Myeloid-Lymphoid Leukemia Protein; Oncogene Proteins, Fusion

2008
Transport and phosphorylation as factors in the antitumor action of cytosine arabinoside.
    Science (New York, N.Y.), 1967, Jun-02, Volume: 156, Issue:3779

    Topics: Animals; Biological Transport; Chromatography, Paper; Cytarabine; In Vitro Techniques; Leukemia L1210; Leukemia, Experimental; Mice; Neoplasm Transplantation; Nucleotides; Phosphates

1967
Nucleic acids. II. Cytotoxicity studies with nucleotides and dinucleoside phosphates containing ara-cytidine.
    Journal of medicinal chemistry, 1967, Volume: 10, Issue:5

    Topics: Animals; Antineoplastic Agents; Culture Techniques; Cytarabine; Cytosine Nucleotides; Leukemia, Experimental; Mice; Neoplasms, Experimental; Nucleosides; Nucleotides

1967
[Experimental research to clinical application of interferons].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:1

    Topics: Animals; Bleomycin; Cytarabine; Drug Therapy, Combination; Humans; Interferon Inducers; Interferon Type I; Interferon-gamma; Interferons; Leukemia, Experimental; Melanoma; Mice; Mitomycin; Mitomycins; Neoplasms; Neoplasms, Experimental

1984
Modulation of human T-cell differentiation markers by 12-O-tetradecanoylphorbol-13-acetate.
    Thymus, 1981, Volume: 3, Issue:4-5

    Topics: 5'-Nucleotidase; Adenosine Deaminase; Adult; Animals; Cell Transformation, Neoplastic; Colony-Forming Units Assay; Cytarabine; DNA; DNA Nucleotidylexotransferase; Histocompatibility Antigens Class II; Humans; Leukemia, Experimental; Nucleotidases; Phorbols; Phytohemagglutinins; Rosette Formation; Sheep; T-Lymphocytes; Tetradecanoylphorbol Acetate

1981
Phosphorylation of selected substrates by semipurified cytoplasmic kinases of three P815 murine leukemias exhibiting collateral sensitivity (P815/TG), sensitivity (P815) or resistance (P815/ARA-C) to 1-beta-D-arabinofuranosylcytosine.
    Biochemical pharmacology, 1982, Dec-01, Volume: 31, Issue:23

    Topics: Animals; Cells, Cultured; Cytarabine; Cytoplasm; Drug Resistance; Leukemia, Experimental; Mice; Phosphorylation; Phosphotransferases

1982
The effects of inhibitors of DNA biosynthesis on the cytotoxicity of 6-thioguanine.
    Cancer biochemistry biophysics, 1981, Volume: 5, Issue:3

    Topics: Animals; Cells, Cultured; Cytarabine; DNA; DNA Replication; Floxuridine; Hydroxyurea; Interphase; Leukemia, Experimental; Mice; Thioguanine

1981
[Radiosensitizing of experimental animal tumors using inhibitors of repair].
    Meditsinskaia radiologiia, 1984, Volume: 29, Issue:12

    Topics: Animals; Cell Survival; Cells, Cultured; Cytarabine; DNA Repair; DNA, Neoplasm; Female; Hydroxyurea; Leukemia, Experimental; Mice; Radiation Tolerance; Sarcoma 37; Sarcoma, Experimental

1984
Acquisition of multiple drug resistance by CCRF-CEM cells selected for different degrees of resistance to vincristine.
    Cancer treatment reports, 1984, Volume: 68, Issue:6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Division; Cell Line; Cell Survival; Cytarabine; Daunorubicin; Doxorubicin; Drug Resistance; Humans; Leukemia, Experimental; Lymphocytes; Phenotype; Vincristine

1984
Comparison of in vitro assays for detecting subpopulations of P388 leukemic cells resistant to AraC.
    Medical oncology and tumor pharmacotherapy, 1984, Volume: 1, Issue:3

    Topics: Animals; Cell Survival; Cytarabine; DNA, Neoplasm; Drug Resistance; Leukemia P388; Leukemia, Experimental; Mice; Tritium

1984
Development of a cell kinetic approach to curative therapy of acute myelocytic leukemia in remission using the cell cycle-specific drug 1-beta-D-arabinofuranosylcytosine in a rat model.
    Cancer research, 1983, Volume: 43, Issue:5

    Topics: Animals; Cell Cycle; Cyclophosphamide; Cytarabine; Drug Administration Schedule; Female; Leukemia, Experimental; Leukemia, Myeloid; Rats

1983
Low dose cytosine arabinoside: partial remission of acute myeloid leukaemia without evidence of differentiation induction.
    British journal of haematology, 1984, Volume: 57, Issue:2

    Topics: Adult; Aged; Animals; Cell Count; Cell Differentiation; Cell Line; Cells, Cultured; Clone Cells; Cytarabine; Female; Humans; Injections, Subcutaneous; Leukemia, Experimental; Leukemia, Myeloid, Acute; Male; Middle Aged

1984
A comparison of the agar cloning and microtitration techniques for assaying cell survival and mutation frequency in L5178Y mouse lymphoma cells.
    Mutation research, 1983, Volume: 111, Issue:3

    Topics: Agar; Animals; Cell Survival; Clone Cells; Culture Media; Culture Techniques; Cytarabine; Leukemia L5178; Leukemia, Experimental; Mice; Mutation; Thioguanine

1983
Effects of inducers of erythroid differentiation of human leukemia K562 cells on vincristine-resistant K562/VCR cells.
    Leukemia research, 1983, Volume: 7, Issue:4

    Topics: Animals; Butyrates; Butyric Acid; Cell Differentiation; Cells, Cultured; Cytarabine; Dactinomycin; Doxorubicin; Drug Resistance; Erythropoiesis; Hemin; Humans; Leukemia, Experimental; Mitomycins; Verapamil; Vincristine

1983
Combination of anticancer agents with folic acid in the treatment of murine leukaemia P388.
    Chemotherapy, 1984, Volume: 30, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Evaluation, Preclinical; Drug Synergism; Fluorouracil; Folic Acid; Leukemia P388; Leukemia, Experimental; Methotrexate; Mice; Mitomycins

1984
Chemotherapy of leukemia in mice, rats, and humans relating time of humoral stimulation, tumor growth, and clinical response.
    Journal of the National Cancer Institute, 1981, Volume: 67, Issue:3

    Topics: Animals; Cell Division; Cytarabine; Daunorubicin; DNA, Neoplasm; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia L1210; Leukemia, Experimental; Leukemia, Myeloid, Acute; Mice; Rats

1981
A rationale for sequential high-dose chemotherapy of leukemia timed to coincide with induced tumor proliferation.
    Blood, 1980, Volume: 55, Issue:6

    Topics: Animals; Cell Transformation, Neoplastic; Cytarabine; Dose-Response Relationship, Drug; Female; Kinetics; Leukemia, Experimental; Rats; Rats, Inbred Lew; Time Factors

1980
Synergistic interaction between 1-beta-D-arabinofuranosylcytosine, thymidine, and hydroxyurea against human B cells and leukemic blasts in vitro.
    Proceedings of the National Academy of Sciences of the United States of America, 1981, Volume: 78, Issue:8

    Topics: Animals; B-Lymphocytes; Cells, Cultured; Cytarabine; DNA Replication; DNA, Neoplasm; Drug Synergism; Drug Therapy, Combination; Humans; Hydroxyurea; Leukemia, Experimental; Thymidine

1981
Chemoimmunotherapy for autochthonous acute rat leukemias.
    Cancer treatment reports, 1982, Volume: 66, Issue:2

    Topics: Animals; Antineoplastic Agents; BCG Vaccine; Cytarabine; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Ethylnitrosourea; Leukemia, Experimental; Male; Rats; Rats, Inbred Strains; Vincristine

1982
Schedule-dependent synergy and antagonism between high-dose 1-beta-D-arabinofuranosylcytosine and asparaginase in the L5178Y murine leukemia.
    Cancer research, 1982, Volume: 42, Issue:6

    Topics: Animals; Asparaginase; Biological Transport; Cell Division; Cell Survival; Cytarabine; Drug Administration Schedule; Drug Antagonism; Drug Synergism; Drug Therapy, Combination; Kinetics; Leukemia L5178; Leukemia, Experimental; Mice; Mitotic Index

1982
Activity of 2-fluoro-5-methylarabinofuranosyluracil against mouse leukemias sensitive to and resistant to 1-beta-D-arabinofuranosylcytosine.
    Cancer research, 1982, Volume: 42, Issue:7

    Topics: Animals; Arabinofuranosyluracil; Cells, Cultured; Cytarabine; Humans; Leukemia L1210; Leukemia P388; Leukemia, Experimental; Mice; Pyrimidine Nucleosides

1982
Biochemical effects of 2'-fluoro-5-methyl-1-beta-D-arabinofuranosyluracil and 2'-fluoro-5-iodo-1-beta-D-arabinofuranosylcytosine in mouse leukemic cells sensitive and resistant to 1-beta-D-arabinofuranosylcytosine.
    Cancer research, 1982, Volume: 42, Issue:10

    Topics: Animals; Arabinofuranosyluracil; Cell Survival; Cytarabine; Deoxycytidine; DNA Replication; Kinetics; Leukemia L1210; Leukemia, Experimental; Mice; Thymidine; Uridine

1982
Recruitment of quiescent tumor by humoral stimulatory activity: requirements for successful chemotherapy.
    Blood cells, 1982, Volume: 8, Issue:3

    Topics: Acute Disease; Animals; Cell Division; Cell Survival; Cells, Cultured; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Leukemia; Leukemia, Experimental; Rats

1982
A recommendation for high-dose Ara-C interval treatment based on studies in a slow-growing leukemia model (BNML).
    Medical and pediatric oncology, 1982, Volume: 10 Suppl 1

    Topics: Animals; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Leukemia, Experimental; Male; Rats

1982
Effects of cytosine arabinoside on DNA synthesis and the clonogenicity of RF/UN murine myeloid leukemia cells.
    Experimental hematology, 1980, Volume: 8, Issue:8

    Topics: Animals; Cell Line; Cell Survival; Colony-Forming Units Assay; Cytarabine; DNA; Friend murine leukemia virus; Hematopoietic Stem Cells; Leukemia, Experimental; Mice

1980
Volume increase in L5222 leukemic cells following chemotherapy: manifestation of leukemic cell damage.
    Leukemia research, 1981, Volume: 5, Issue:1

    Topics: Animals; Ascitic Fluid; Cytarabine; Daunorubicin; Fluorouracil; Hydroxyurea; Leukemia, Experimental; Rats; Vincristine

1981
Comparative chemotherapeutic investigations on transplanted and autochthonous acute rat leukemias.
    Journal of cancer research and clinical oncology, 1981, Volume: 100, Issue:3

    Topics: Acute Disease; Animals; Antineoplastic Agents; Cytarabine; Doxorubicin; Drug Therapy, Combination; Leukemia, Experimental; Male; Neoplasm Transplantation; Prognosis; Rats; Vincristine

1981
The induction and characterization of mouse lymphoma L5178Y cell lines resistant to 1-beta-d-arabinofuranosylcytosine.
    Mutation research, 1980, Volume: 69, Issue:1

    Topics: 2-Acetylaminofluorene; Animals; Cell Line; Cytarabine; Drug Resistance; Ethidium; Ethyl Methanesulfonate; Leukemia L5178; Leukemia, Experimental; Mice; Mutagens; Mutation; Thymidine

1980
Acquisition of selected subpopulations of leukemic cells for study.
    Antibiotics and chemotherapy, 1980, Volume: 28

    Topics: Animals; Cell Separation; Cytarabine; DNA, Neoplasm; Doxorubicin; Humans; Leukemia, Experimental; Lymphocytes; Mice; Spleen

1980
[Effect of deoxycytidine on the efficacy of cytosine arabinoside in BALB/C mice with Rauscher erythroblastic leukemia].
    Biulleten' eksperimental'noi biologii i meditsiny, 1980, Volume: 90, Issue:10

    Topics: Animals; Cytarabine; Deoxycytidine; Drug Combinations; Female; Leukemia, Experimental; Mice; Mice, Inbred BALB C; Organ Size; Rauscher Virus; Spleen

1980
Lymph node metastasis and effects of 1-beta-D-arabinofuranosylcytosine, 5-fluorouracil, and their lipophilic derivatives in an experimental model system using P388 leukemia.
    Cancer research, 1980, Volume: 40, Issue:12

    Topics: Animals; Cytarabine; Female; Fluorouracil; Leukemia, Experimental; Lymphatic Metastasis; Mice; Solubility; Structure-Activity Relationship

1980
Transfection of wild-type deoxycytidine kinase (dck) cDNA into an AraC- and DAC-resistant rat leukemic cell line of clonal origin fully restores drug sensitivity.
    Blood, 1995, Mar-01, Volume: 85, Issue:5

    Topics: Animals; Azacitidine; Base Sequence; Cytarabine; Decitabine; Deoxycytidine Kinase; DNA, Complementary; Drug Resistance; Leukemia, Experimental; Molecular Sequence Data; Phosphorylation; Rats; Recombinant Fusion Proteins; RNA, Messenger; Transfection; Tumor Cells, Cultured

1995
De novo induced mutations in the deoxycytidine kinase (dck) gene in rat leukemic clonal cell lines confer resistance to cytarabine (AraC) and 5-aza-2'-deoxycytidine (DAC).
    Leukemia, 1995, Volume: 9, Issue:6

    Topics: Animals; Antineoplastic Agents; Azacitidine; Blotting, Southern; Cell Line; Cytarabine; Decitabine; Deoxycytidine Kinase; Drug Resistance; Gene Expression; Kinetics; Leukemia, Experimental; Polymerase Chain Reaction; Polymorphism, Genetic; Rats; Restriction Mapping; Time Factors; Transcription, Genetic; Tumor Cells, Cultured

1995
Teaching cancer chemotherapy by means of a computer simulation.
    International journal of bio-medical computing, 1994, Volume: 36, Issue:4

    Topics: Animals; Antineoplastic Agents; Carcinoma; Cause of Death; Computer Simulation; Computer-Assisted Instruction; Cyclophosphamide; Cytarabine; Drug Administration Schedule; Drug Screening Assays, Antitumor; Humans; Leukemia, Experimental; Melanoma; Methotrexate; Mice; Models, Biological; Models, Educational; Neoplasms, Experimental; Sarcoma, Experimental; Software; Survival Rate; Teaching

1994
Chronobiology as it relates to toxicology, pharmacology, and chemotherapy.
    Regulatory toxicology and pharmacology : RTP, 1993, Volume: 17, Issue:2 Pt 1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Circadian Rhythm; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Resistance; Humans; Leukemia, Experimental; Mice

1993
Activation of the LRP (lung resistance-related protein) gene by short-term exposure of human leukemia cells to phorbol ester and cytarabine.
    Oncology research, 1998, Volume: 10, Issue:4

    Topics: Antimetabolites, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinogens; Cytarabine; Gene Expression Regulation, Leukemic; Genes, MDR; HL-60 Cells; Humans; K562 Cells; Leukemia, Experimental; Leukemia, T-Cell; Neoplasm Proteins; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcriptional Activation; Tumor Cells, Cultured; Vault Ribonucleoprotein Particles

1998
Antitumor activity of P-4055 (elaidic acid-cytarabine) compared to cytarabine in metastatic and s.c. human tumor xenograft models.
    Cancer research, 1999, Jun-15, Volume: 59, Issue:12

    Topics: Animals; Antimetabolites, Antineoplastic; Biological Transport; Carcinoma; Carrier Proteins; Cytarabine; Disease Models, Animal; Drug Screening Assays, Antitumor; Fatty Acids, Unsaturated; Female; Humans; Leukemia L1210; Leukemia, Experimental; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Nucleoside Transport Proteins; Rats; Rats, Nude; Transplantation, Heterologous; Tumor Cells, Cultured

1999
Leukemia cell lines resistant to cytosine arabinoside, cyclophosphamide or daunomycin are equally sensitive to the drug acetyldinaline as the parental cell line.
    Leukemia, 2000, Volume: 14, Issue:1

    Topics: Animals; Antineoplastic Agents; Benzamides; Cyclophosphamide; Cytarabine; Daunorubicin; Disease Models, Animal; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Leukemia, Experimental; Phenylenediamines; Rats; Tumor Cells, Cultured

2000
The interaction of gemcitabine and cytarabine on murine leukemias L1210 or P388 and on human normal and leukemic cell growth in vitro.
    Haematologica, 2000, Volume: 85, Issue:6

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cell Culture Techniques; Cytarabine; Deoxycytidine; Gemcitabine; Humans; Leukemia, Experimental; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Mice; Mice, Inbred Strains; Stem Cells; Tumor Cells, Cultured

2000
Cystathionine-beta-synthase cDNA transfection alters the sensitivity and metabolism of 1-beta-D-arabinofuranosylcytosine in CCRF-CEM leukemia cells in vitro and in vivo: a model of leukemia in Down syndrome.
    Cancer research, 2000, Nov-15, Volume: 60, Issue:22

    Topics: Animals; Antimetabolites, Antineoplastic; Chromosomes, Human, Pair 21; Cystathionine beta-Synthase; Cytarabine; Deoxycytidine Kinase; DNA, Complementary; Down Syndrome; Female; Gene Expression; Humans; Leukemia, Experimental; Male; Mice; Mice, Inbred ICR; Mice, SCID; Transfection; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2000
Cellular phosphorylation of 1-beta-D-arabinofuranosylcytosine 5-azacytidine with intact fibrosarcoma and leukemic cells.
    Cancer research, 1975, Volume: 35, Issue:9

    Topics: Animals; Azacitidine; Binding, Competitive; Cells, Cultured; Cricetinae; Cytarabine; Cytidine; Deoxycytidine; Drug Resistance; Fibrosarcoma; Kinetics; Leukemia, Experimental; Mice; Phosphorus; Sarcoma, Experimental

1975
Chemotherapeutic remissions in Wistar Furth rat acute myelogenous leukemia: a model for human AML.
    Acta haematologica, 1977, Volume: 57, Issue:4

    Topics: Animals; Antineoplastic Agents; Busulfan; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Dexamethasone; Disease Models, Animal; Doxorubicin; Leukemia, Experimental; Leukemia, Myeloid, Acute; Methotrexate; Rats; Remission, Spontaneous; Vinblastine; Vincristine

1977
In vitro induction of polyclonal killer T cells with 2-mercaptoethanol and the essential role of macrophages in this process.
    Journal of immunology (Baltimore, Md. : 1950), 1977, Volume: 118, Issue:5

    Topics: Animals; Antigens, Neoplasm; Burkitt Lymphoma; Cell Division; Cells, Cultured; Clone Cells; Cytarabine; Cytotoxicity Tests, Immunologic; DNA; Epitopes; Female; Hydroxyurea; Immunity, Cellular; In Vitro Techniques; Leukemia, Experimental; Macrophages; Mast-Cell Sarcoma; Mercaptoethanol; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Plasmacytoma; T-Lymphocytes

1977
Synergistic effects of the combination of cis-platinum diamminodichloride and 2,2'-anhydro-1-beta-D-arabinofuranosyl-5-fluorocytosine in transplanted mouse leukemias.
    Cancer research, 1977, Volume: 37, Issue:11

    Topics: Ancitabine; Animals; Cells, Cultured; Cisplatin; Cytarabine; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Leukemia L1210; Leukemia, Experimental; Methotrexate; Mice; Mice, Inbred C57BL; Mice, Inbred DBA

1977
Technique for preclinical evaluation of continuous infusion chemotherapy with the use of WF rat acute myelogenous leukemia.
    Journal of the National Cancer Institute, 1979, Volume: 62, Issue:5

    Topics: Animals; Antineoplastic Agents; Cytarabine; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Infusions, Parenteral; Injections, Intravenous; Leukemia, Experimental; Leukemia, Myeloid, Acute; Rats; Rats, Inbred WF; Thymidine; Zinostatin

1979
A phospholipid derivative of cytosine arabinoside and its conversion to phosphatidylinositol by animal tissue.
    Science (New York, N.Y.), 1977, Apr-15, Volume: 196, Issue:4287

    Topics: Animals; Biotransformation; CDPdiacylglycerol-Serine O-Phosphatidyltransferase; Cytarabine; Diglycerides; Glycerides; Humans; Leukemia, Experimental; Liver; Mice; Phosphatidylglycerols; Phosphatidylinositols; Phosphotransferases; Rats

1977
Metabolism and intracellular retention of 1-beta-D-arabinofuranosylcytosine as predictors of response of animal tumors.
    Cancer research, 1978, Volume: 38, Issue:3

    Topics: Animals; Carcinoma, Hepatocellular; Cytarabine; Female; Leukemia L1210; Leukemia, Experimental; Liver Neoplasms; Mice; Mice, Inbred DBA; Neoplasms, Experimental; Tissue Distribution

1978
Pyrimidine nucleoside monophosphate kinase from human leukemic blast cells.
    Cancer research, 1978, Volume: 38, Issue:3

    Topics: Animals; Cell Line; Cytarabine; Deoxycytidine Monophosphate; Humans; In Vitro Techniques; Kinetics; Leukemia, Experimental; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Molecular Weight; Nucleoside-Phosphate Kinase; Phosphotransferases; Pyrimidine Nucleotides; Sulfhydryl Reagents

1978
Formation of 1-beta-D-arabinofuranosylcytosine diphosphate choline in cultured human leukemic RPMI 6410 cells.
    Cancer research, 1978, Volume: 38, Issue:6

    Topics: 3-Deazauridine; Animals; Cell Division; Cells, Cultured; Choline; Cytarabine; Cytidine Diphosphate Choline; Drug Synergism; Humans; Hydrolysis; Leukemia, Experimental; Leukemia, Myeloid, Acute

1978
Formation of 1-beta-D-arabinofuranosylcytosine diphosphate choline in neoplastic and normal cells.
    Cancer research, 1978, Volume: 38, Issue:6

    Topics: 3-Deazauridine; Animals; Choline; Cytarabine; Cytidine Diphosphate Choline; Drug Synergism; Female; HeLa Cells; Leukemia L1210; Leukemia, Experimental; Leukemia, Myeloid, Acute; Liver; Lymphocytes; Mice; Mice, Inbred Strains

1978
Relevance of recruitment-synchronization in the scheduling of 1-beta-D-arabinofuranosylcytosine in a slow-growing acute myeloid leukemia of the rat.
    Cancer research, 1979, Volume: 39, Issue:7 Pt 1

    Topics: Animals; Cell Cycle; Colony-Forming Units Assay; Cytarabine; Hematopoietic Stem Cells; Interphase; Leukemia, Experimental; Leukemia, Myeloid, Acute; Male; Mice; Mice, Inbred Strains; Neoplasm Transplantation

1979
Leukemias induced by ethylnitrosourea in Wistar rats: incidence and chemotherapy.
    Leukemia research, 1979, Volume: 3, Issue:4

    Topics: Acute Disease; Animals; Cytarabine; Doxorubicin; Drug Therapy, Combination; Ethylnitrosourea; Leukemia, Experimental; Leukemia, Myeloid; Leukocyte Count; Male; Nitrosourea Compounds; Rats; Vincristine

1979
BN rat myeloid leukemia transferred to the (LEW x BN)F1 rat.
    Journal of the National Cancer Institute, 1978, Volume: 61, Issue:3

    Topics: Animals; Cytarabine; Female; Leukemia, Experimental; Leukemia, Myeloid; Neoplasm Transplantation; Rats; Rats, Inbred BN; Rats, Inbred Lew; Transplantation, Homologous

1978
Differential cell-cycle-dependent inhibition of DNA synthesis by hydroxyurea and cytosine arabinoside in cultured L5178Y mouse lymphoma cells.
    Archivum immunologiae et therapiae experimentalis, 1979, Volume: 27, Issue:4

    Topics: Animals; Cell Cycle; Cell Line; Cytarabine; DNA, Neoplasm; Hydroxyurea; Leukemia L5178; Leukemia, Experimental; Mice; Mitosis

1979
A quantitative approach to the design of antitumor drug dosage schedule via cell cycle kinetics and systems theory.
    Annals of biomedical engineering, 1977, Volume: 5, Issue:1

    Topics: Animals; Antineoplastic Agents; Cell Division; Cell Survival; Cytarabine; DNA, Neoplasm; Drug Administration Schedule; Kinetics; Leukemia, Experimental; Models, Biological; Models, Chemical; Neoplasms

1977
Mode of action of 5-fluorouridine 5'-phosphate in vivo and in vitro.
    Chemical & pharmaceutical bulletin, 1978, Volume: 26, Issue:2

    Topics: Animals; Antimetabolites, Antineoplastic; Cells, Cultured; Cytarabine; Fluorouracil; Leukemia L1210; Leukemia, Experimental; Mice; Nucleic Acid Precursors; Uracil Nucleotides

1978
Experimental therapeutics and kinetics: selection and overgrowth of specifically and permanently drug-resistant tumor cells.
    Seminars in hematology, 1978, Volume: 15, Issue:3

    Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Drug Resistance; Kinetics; Leukemia, Experimental; Mice

1978
Enhancement of anti-tumor activity of 1-beta-D-arabinofuranosylcytosine by encapsulation in liposomes.
    International journal of cancer, 1977, Oct-15, Volume: 20, Issue:4

    Topics: Administration, Oral; Amines; Animals; Cholesterol; Cytarabine; Drug Synergism; Female; Injections, Intravenous; Injections, Subcutaneous; Leukemia, Experimental; Liposomes; Mice; Mice, Inbred Strains; Sphingomyelins

1977
[A modified screening model for potential cancerostatics by i.v. application of L 1210 ascites cells (author's transl)].
    Archiv fur Geschwulstforschung, 1976, Volume: 46, Issue:6

    Topics: Animals; Cyclophosphamide; Cytarabine; Drug Evaluation, Preclinical; Leukemia, Experimental; Mice; Mice, Inbred DBA; Models, Biological

1976
[Cytokinetics, chemotherapy and clinical course of acute leukemias].
    Minerva medica, 1975, Jul-14, Volume: 66, Issue:51

    Topics: Animals; Antineoplastic Agents; Cytarabine; Humans; Kinetics; Leukemia, Experimental; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mice; Mitosis; Prognosis

1975
Experimental and clinical studies on nucleoside analogs as antitumor agents.
    Annals of the New York Academy of Sciences, 1975, Aug-08, Volume: 255

    Topics: Aged; Animals; Cytarabine; Drug Resistance; Flucytosine; Fluorouracil; Humans; Leukemia L1210; Leukemia, Experimental; Male; Methotrexate; Mice; Nasopharyngeal Neoplasms; Structure-Activity Relationship

1975
Immunosuppression in cancer therapeutics.
    Transplantation proceedings, 1975, Volume: 7, Issue:2

    Topics: Animals; Cytarabine; Graft Rejection; Humans; Hydrazones; Immunosuppressive Agents; Leukemia, Experimental; Mice; Mice, Inbred CBA; Mice, Inbred DBA; Skin Transplantation; Transplantation, Homologous

1975
Chemotherapy of the transplantable acute leukemia L5222 in rats.
    Cancer research, 1975, Volume: 35, Issue:5

    Topics: Acute Disease; Animals; Antineoplastic Agents; Asparaginase; Carmustine; Cell Division; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Hydrazones; Leukemia, Experimental; Male; Mercaptopurine; Neoplasm Transplantation; Prednisolone; Rats; Transplantation, Homologous; Vincristine

1975
Sensitivity of DBLA-6 leukemia of rats to known antitumor agents in relation to their clinical effects.
    Bibliotheca haematologica, 1975, Issue:40

    Topics: Alkylating Agents; Animals; Antineoplastic Agents; Cell Line; Cyclophosphamide; Cytarabine; Daunorubicin; Injections, Intravenous; Leukemia, Experimental; Mercaptopurine; Methotrexate; Nitrosourea Compounds; Rats; Vinblastine; Vincristine

1975
Cytosine arabinoside uptake by tumour cells in vitro.
    European journal of cancer, 1975, Volume: 11, Issue:5

    Topics: Animals; Cytarabine; Deoxycytidine; Diffusion; Female; In Vitro Techniques; Kinetics; Leukemia L1210; Leukemia, Experimental; Neoplasms, Experimental; Rats; Sarcoma, Yoshida

1975
R17934-NSC238159: a new antitumor drug--II. Effect on mitotic cycle of L1210 leukemia cells in vivo and synergism with cytosine arabinoside (NSC63878).
    European journal of cancer, 1975, Volume: 11, Issue:9

    Topics: Animals; Antineoplastic Agents; Benzimidazoles; Carbamates; Cytarabine; Drug Synergism; Drug Therapy, Combination; Leukemia L1210; Leukemia, Experimental; Mice; Mitosis

1975
Response of L1210 to combinations of cytosine arabinoside and VM-26 or VP16-213.
    European journal of cancer, 1975, Volume: 11, Issue:9

    Topics: Animals; Cytarabine; Drug Therapy, Combination; Etoposide; Female; Leukemia L1210; Leukemia, Experimental; Mice; Podophyllotoxin; Pyrans; Teniposide

1975
Action of 5-fluorocyclocytidine on cultured L-5178Y cells.
    Gan, 1975, Volume: 66, Issue:5

    Topics: Animals; Cell Line; Cytarabine; Deoxyribonucleosides; DNA, Neoplasm; Leucine; Leukemia, Experimental; Neoplasm Proteins; RNA, Neoplasm; Thymidine; Uridine

1975
Effect of tetrahydrouridine on metabolism and transport of 1-beta-D-arabinofuranosylcytosine in human cells.
    Chemotherapy, 1992, Volume: 38, Issue:5

    Topics: Cells, Cultured; Cytarabine; Humans; Leukemia, Experimental; Liver; Nucleoside Deaminases; Tetrahydrouridine; Tumor Cells, Cultured

1992
Hematopoietic cytokines inhibit apoptosis induced by transforming growth factor beta 1 and cancer chemotherapy compounds in myeloid leukemic cells.
    Blood, 1992, Oct-01, Volume: 80, Issue:7

    Topics: Animals; Antineoplastic Agents; Apoptosis; Azides; Cell Survival; Cycloheximide; Cytarabine; Cytokines; DNA Damage; Dose-Response Relationship, Drug; Doxorubicin; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoiesis; Hematopoietic Cell Growth Factors; Interferon Type I; Interleukin-1; Interleukin-3; Interleukin-6; Leukemia, Experimental; Leukemia, Myeloid; Mice; Recombinant Proteins; Sodium Azide; Stem Cell Factor; Transforming Growth Factor beta; Tumor Cells, Cultured; Vincristine

1992
[Antitumor drugs and potentiators aiming circumvention of drug resistance].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:3 Pt 1

    Topics: Animals; Antineoplastic Agents; Bleomycin; Carcinoma, Ehrlich Tumor; Cytarabine; Drug Resistance; Drug Screening Assays, Antitumor; Drug Synergism; Leukemia, Experimental; Mice; Peplomycin

1990
Induction of deoxycytidine kinase by 5-azacytidine in an HL-60 cell line resistant to arabinosylcytosine.
    Molecular pharmacology, 1991, Volume: 39, Issue:2

    Topics: Azacitidine; Base Sequence; Cytarabine; Deoxycytidine; Deoxycytidine Kinase; DNA, Neoplasm; Drug Resistance; Enzyme Induction; Humans; Kinetics; Leukemia, Experimental; Leukemia, Myeloid; Methylation; Molecular Sequence Data; Time Factors; Tritium; Tumor Cells, Cultured

1991
Laboratory determination of chemotherapeutic drug resistance in tumor cells from patients with leukemia, using a fluorometric microculture cytotoxicity assay (FMCA).
    International journal of cancer, 1992, Jan-21, Volume: 50, Issue:2

    Topics: Antineoplastic Agents; Cytarabine; Doxorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Fluorometry; Humans; Leukemia, Experimental; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Tumor Cells, Cultured

1992
Activation of the transcription factor kappa B in human KG-1 myeloid leukemia cells treated with 1-beta-D-arabinofuranosylcytosine.
    Molecular pharmacology, 1992, Volume: 41, Issue:1

    Topics: Base Sequence; Cytarabine; DNA; Electrophoresis; Gene Expression Regulation, Leukemic; Humans; Leukemia, Experimental; Leukemia, Myeloid; Molecular Sequence Data; NF-kappa B; Nuclear Proteins; Signal Transduction; Transcription, Genetic; Translocation, Genetic; Tumor Cells, Cultured

1992
Transcriptional and posttranscriptional regulation of H1 histone gene expression by 1-beta-D-arabinofuranosylcytosine.
    Molecular pharmacology, 1992, Volume: 41, Issue:1

    Topics: Cycloheximide; Cytarabine; Dactinomycin; Down-Regulation; Gene Expression Regulation, Leukemic; Histones; Humans; Leukemia, Experimental; Leukemia, Myeloid; Protein Processing, Post-Translational; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured

1992
[Clinical pharmacology of anticancer agents (Part 4). Antimetabolites (1)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:2

    Topics: Animals; Antimetabolites; Cytarabine; Fluorouracil; Leukemia, Experimental; Nucleotides; Permeability; Pyrimidines; Tumor Cells, Cultured

1992
Inhibition by 1,25 dihydroxyvitamin D3 of chemically induced erythroid differentiation of K562 leukemia cells.
    Blood, 1991, Apr-01, Volume: 77, Issue:7

    Topics: Animals; Calcitriol; Cell Differentiation; Cell Division; Cell Line; Cytarabine; Humans; Kinetics; Leukemia, Experimental; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Receptors, Calcitriol; Receptors, Steroid; Ribavirin; RNA, Messenger; Time Factors

1991
In vitro effects of bryostatin 1 on the metabolism and cytotoxicity of 1-beta-D-arabinofuranosylcytosine in human leukemia cells.
    Biochemical pharmacology, 1991, Jul-25, Volume: 42, Issue:4

    Topics: Antineoplastic Agents; Arabinofuranosylcytosine Triphosphate; Bryostatins; Cell Count; Cytarabine; Diterpenes; DNA, Neoplasm; Humans; Kinetics; Lactones; Leukemia, Experimental; Leukemia, Myeloid; Macrolides; Phorbol 12,13-Dibutyrate; Phosphorylation; Terpenes; Time Factors; Tumor Cells, Cultured

1991
Comparison of antineoplastic activity of 2',2'-difluorodeoxycytidine and cytosine arabinoside against human myeloid and lymphoid leukemic cells.
    Anti-cancer drugs, 1991, Volume: 2, Issue:1

    Topics: Antimetabolites, Antineoplastic; Cell Division; Cytarabine; Deoxycytidine; DNA, Neoplasm; Gemcitabine; Humans; Kinetics; Leukemia, Experimental; Leukemia, Lymphoid; Leukemia, Myeloid; Phenotype; Tumor Cells, Cultured

1991
Synergism of ara-C-imuvert combination in aborting the development of transplanted chloroleukemia in the rat.
    The American journal of the medical sciences, 1991, Volume: 301, Issue:2

    Topics: Animals; Biological Products; Cell Differentiation; Cell Division; Colony-Forming Units Assay; Colony-Stimulating Factors; Cytarabine; Drug Synergism; Immunologic Factors; In Vitro Techniques; Leukemia, Experimental; Monocytes; Rats; Tumor Cells, Cultured

1991
Improved prognosis in mice with advanced myeloid leukemia following administration of GM-CSF and cytosine arabinoside.
    Leukemia research, 1991, Volume: 15, Issue:5

    Topics: Animals; Bone Marrow; Colony-Forming Units Assay; Combined Modality Therapy; Cytarabine; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cells; Leukemia, Experimental; Leukemia, Myeloid; Male; Mice; Mice, Inbred BALB C; Recombinant Proteins

1991
Expression of transcobalamin II receptors by human leukemia K562 and HL-60 cells.
    Blood, 1990, Oct-01, Volume: 76, Issue:7

    Topics: Cell Division; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Cobalt Radioisotopes; Cytarabine; Dose-Response Relationship, Drug; Down-Regulation; Gene Expression; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Experimental; Leukemia, Myeloid; Receptors, Cell Surface; Transcobalamins; Trypsin; Up-Regulation; Vitamin B 12

1990
Protection from chemotherapy-induced alopecia in a rat model.
    Science (New York, N.Y.), 1990, Sep-28, Volume: 249, Issue:4976

    Topics: Alopecia; Animals; Biological Products; Cytarabine; Disease Models, Animal; Immunologic Factors; Leukemia, Experimental; Rats; Rats, Inbred F344; Skin

1990
A simplified assay for measurement of cytosine arabinoside incorporation into DNA in Ara-C-sensitive and -resistant leukemic cells.
    Cancer chemotherapy and pharmacology, 1990, Volume: 27, Issue:2

    Topics: Animals; Cell Line; Chromatography, High Pressure Liquid; Cytarabine; DNA, Neoplasm; Humans; Leukemia, Experimental; Radioimmunoassay; Rats

1990
Synthesis of a 60 kD nuclear DNA binding protein induced by cytosine arabinoside in the HL 60 leukemic cell line.
    European journal of haematology, 1990, Volume: 44, Issue:3

    Topics: Cell Line; Chromatography, Affinity; Cytarabine; DNA-Binding Proteins; Dose-Response Relationship, Drug; Humans; Leukemia, Experimental; Leukemia, Myeloid; Methionine; Molecular Weight

1990
Enhanced retention of cytosine arabinoside and its metabolites and synergistic cytotoxicity by sequential treatment with dipyridamole in L5178Y leukemia.
    Cancer chemotherapy and pharmacology, 1990, Volume: 26, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dipyridamole; DNA; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Leukemia, Experimental; Mice; Time Factors; Tritium

1990
[Kinetics of etoposide cytotoxicity against mouse P388 leukemia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:11

    Topics: Animals; Bleomycin; Cell Cycle; Cell Survival; Cisplatin; Colony-Forming Units Assay; Cytarabine; Doxorubicin; Etoposide; Fluorouracil; Leukemia P388; Leukemia, Experimental; Melphalan; Mice; Peplomycin; Podophyllotoxin; Tumor Stem Cell Assay; Vinblastine

1985
Differential effect of collaterally sensitive antimetabolites on P388 murine leukemia sensitive and resistant to adriamycin in vitro.
    Neoplasma, 1989, Volume: 36, Issue:6

    Topics: Animals; Antimetabolites, Antineoplastic; Aphidicolin; Cytarabine; Diterpenes; DNA Polymerase II; DNA, Neoplasm; Doxorubicin; Drug Resistance; Hydroxyurea; Inosine; Leukemia P388; Leukemia, Experimental; Mice; Ribonucleotide Reductases; RNA, Neoplasm; Tumor Cells, Cultured

1989
The covalent linking of two nucleotide analogues to antibodies.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:1

    Topics: Animals; Antibodies; Cytarabine; Dextrans; Dosage Forms; Leukemia, Experimental; Mice; Uridine

1985
Intracellular pharmacokinetics of N4-behenoyl-1-beta-D-arabinofuranosylcytosine.
    Advances in experimental medicine and biology, 1989, Volume: 253B

    Topics: Animals; Antineoplastic Agents; Chromatography, High Pressure Liquid; Cytarabine; DNA; Leukemia P388; Leukemia, Experimental; Mice; Tumor Cells, Cultured

1989
Modulation of the metabolism and pharmacokinetics of 1-beta-D-arabinofuranosylcytosine by 1-beta-D-arabinofuranosyluracil in leukemic mice.
    Cancer research, 1989, Jun-15, Volume: 49, Issue:12

    Topics: Animals; Arabinofuranosyluracil; Cytarabine; Cytidine Deaminase; Kidney; Kinetics; Leukemia L5178; Leukemia, Experimental; Liver; Male; Mice; Mice, Inbred Strains; Uridine

1989
Increased sensitivity to 1-beta-D-arabinofuranosylcytosine in P388 murine leukemic cells resistant to etoposide.
    Leukemia research, 1989, Volume: 13, Issue:1

    Topics: Animals; Arabinofuranosylcytosine Triphosphate; Cell Line; Cytarabine; Deoxyribonucleotides; Drug Resistance; Etoposide; Leukemia P388; Leukemia, Experimental; Mice

1989
Effect of cytarabine upon metabolism of phospholipids in leukemia L5178Y cells.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1986, Volume: 7, Issue:4

    Topics: Animals; Cell Line; Cytarabine; Leukemia L5178; Leukemia, Experimental; Mice; Phospholipids

1986
Regulation of cell surface receptors for different hematopoietic growth factors on myeloid leukemic cells.
    The EMBO journal, 1986, Volume: 5, Issue:9

    Topics: Animals; Bone Marrow; Cell Differentiation; Cell Line; Cytarabine; Dactinomycin; Growth Substances; Leukemia, Experimental; Lymph Nodes; Macrophages; Mice; Mice, Inbred Strains; Receptors, Cell Surface; Thymus Gland

1986
The effects of leukemosuppressive immunotherapy on bone marrow infectious cell centers in AKR mice.
    Virology, 1987, Volume: 157, Issue:2

    Topics: Animals; Antigens, Viral; Bone Marrow; Cytarabine; Dexamethasone; Friend murine leukemia virus; Glycoproteins; Hematopoietic Stem Cells; Immunization, Passive; Leukemia Virus, Murine; Leukemia, Experimental; Mice; Mice, Inbred AKR; T-Lymphocytes; Viral Envelope Proteins

1987
Doxycycline in combination chemotherapy of a rat leukemia.
    Cancer research, 1988, Dec-01, Volume: 48, Issue:23

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Doxorubicin; Doxycycline; Leukemia, Experimental; Male; Rats

1988
Cell killing and mutagenesis by alkylating agents and UV irradiation in wild-type and deoxycytidine-kinase-deficient Friend murine leukaemia cells.
    Mutagenesis, 1988, Volume: 3, Issue:2

    Topics: Animals; Cell Survival; Clone Cells; Cytarabine; Drug Resistance; Ethyl Methanesulfonate; Leukemia, Experimental; Methyl Methanesulfonate; Mice; Mutagenicity Tests; Mutation; Ultraviolet Rays

1988
Elevation of blood levels of zinc protoporphyrin by radiomimetic drugs and Friend leukemia virus.
    Acta oncologica (Stockholm, Sweden), 1987, Volume: 26, Issue:3

    Topics: Animals; Antineoplastic Agents; Bone Marrow Transplantation; Cyclophosphamide; Cytarabine; Erythropoiesis; Folic Acid Deficiency; Friend murine leukemia virus; Hydroxyurea; Leukemia, Experimental; Male; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Porphyrins; Protoporphyrins; Radiation Dosage; Radiation Effects; Whole-Body Irradiation

1987
Deamination rates of 1-beta-D-arabinofuranosylcytosine, deoxycytidine and 5-methyl-2'-deoxycytidine in seven hematopoietic cell lines.
    Medical biology, 1987, Volume: 65, Issue:4

    Topics: Animals; Cell Line; Cytarabine; Cytidine Deaminase; Deamination; Deoxycytidine; Hematopoietic Stem Cells; Humans; Leukemia, Experimental; Nucleoside Deaminases; Sonication

1987
Control of proliferating potential of myeloid leukemia cells during long-term treatment with vitamin D3 analogues and other differentiation inducers in combination with antileukemic drugs: in vitro and in vivo studies.
    Cancer research, 1987, Jan-15, Volume: 47, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Calcitriol; Cell Differentiation; Cell Division; Cytarabine; Dactinomycin; Daunorubicin; Dexamethasone; Hydroxycholecalciferols; Leukemia, Experimental; Leukemia, Myeloid, Acute; Mice; Time Factors

1987
In vivo development of cytosine arabinoside resistance in the BN acute myelocytic leukemia.
    Seminars in oncology, 1987, Volume: 14, Issue:2 Suppl 1

    Topics: Animals; Cell Line; Cytarabine; Cytidine Deaminase; Deoxycytidine Kinase; Drug Resistance; Leukemia, Experimental; Leukemia, Myeloid, Acute; Nucleoside Deaminases; Rats

1987
Drug induced host factors which stimulate growth of residual leukemia in Lewis x Brown Norway F1 (LEW-BN) rats.
    Cancer research, 1986, Volume: 46, Issue:4 Pt 1

    Topics: Animals; Bone Marrow; Cytarabine; Drug Administration Schedule; Female; Growth Substances; Leukemia, Experimental; Rats; Rats, Inbred BN; Rats, Inbred Lew

1986
1-beta-D-arabinofuranosylcytosine conjugates of thioether phospholipids as a new class of potential antitumor drugs.
    Cancer drug delivery, 1986,Spring, Volume: 3, Issue:2

    Topics: Animals; Antineoplastic Agents; Arabinonucleotides; Cytarabine; Cytidine Monophosphate; Leukemia L1210; Leukemia P388; Leukemia, Experimental; Male; Mice; Mice, Inbred DBA; Structure-Activity Relationship

1986
Therapeutic synergism of tiazofurin and selected antitumor drugs against sensitive and resistant P388 leukemia in mice.
    Cancer research, 1986, Volume: 46, Issue:7

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Cisplatin; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Female; Leukemia P388; Leukemia, Experimental; Mice; Phosphonoacetic Acid; Ribavirin; Ribonucleosides; Thioguanine

1986
Effects of chemotherapy on bone marrow stroma in mice with acute myelogenous leukemia. Correlation with CFU-C and CFU-D.
    Leukemia research, 1985, Volume: 9, Issue:8

    Topics: Animals; Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Cytarabine; Diffusion; Doxorubicin; Fibroblasts; Granulocytes; Hematopoietic Stem Cells; Hydroxyurea; Leukemia, Experimental; Leukemia, Myeloid, Acute; Macrophages; Male; Mice; Mice, Inbred C57BL; Time Factors

1985
[Effects of combination chemotherapy of MCNU with various anti-cancer agents].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Doxorubicin; Female; Fluorouracil; Leukemia L1210; Leukemia P388; Leukemia, Experimental; Mercaptopurine; Methotrexate; Mice; Mice, Inbred DBA; Mitomycin; Mitomycins; Nitrosourea Compounds; Thioguanine

1985
Effect of uracil arabinoside on metabolism and cytotoxicity of cytosine arabinoside in L5178Y murine leukemia.
    The Journal of clinical investigation, 1985, Volume: 75, Issue:1

    Topics: Animals; Arabinofuranosyluracil; Cytarabine; Cytotoxicity, Immunologic; Drug Interactions; Humans; Kinetics; Leukemia L5178; Leukemia, Experimental; Tumor Stem Cell Assay; Uridine

1985
Experimental investigations on problems of the clinical use of L-asparaginase.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1970, Volume: 33

    Topics: Animals; Antibody Formation; Antineoplastic Agents; Asparaginase; Cytarabine; Dactinomycin; Drug Resistance; Drug Synergism; Escherichia coli; Immunization; Immunosuppressive Agents; Leukemia, Experimental; Melphalan; Mice; Mice, Inbred Strains; Neoplasm Metastasis; Neoplasm Transplantation; Podophyllin; Procarbazine; Time Factors; Vincristine

1970
Sensitivity of transplantable rat leukemia, DBLA-6, to antitumor agents.
    Gan, 1972, Volume: 63, Issue:3

    Topics: Alkanesulfonates; Animals; Antineoplastic Agents; Asparaginase; Biphenyl Compounds; Bleomycin; Cell Line; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Leukemia, Experimental; Leukocyte Count; Mercaptopurine; Methotrexate; Mitomycins; Neoplasm Transplantation; Nitrosourea Compounds; Rats; Streptococcus; Tosyl Compounds; Vinblastine; Vincristine

1972
Enhancement of erythrocytic maturation of Friend virus-induced leukemia cells in vivo.
    Bibliotheca haematologica, 1973, Volume: 39

    Topics: Animals; Anti-Bacterial Agents; Ascitic Fluid; Bleomycin; Cell Line; Cells, Cultured; Clone Cells; Cytarabine; Dimethyl Sulfoxide; DNA; Erythrocyte Aging; Fluorescent Antibody Technique; Friend murine leukemia virus; Glycerol; Leukemia, Experimental; Male; Mice; Microscopy, Electron; Mitomycins; Nitrogen Mustard Compounds; Retroviridae; Rifampin; Vincristine

1973
Studies on a new mechanism of resistance of L5178Y murine leukemia cells to cytosine arabinoside.
    Biochimica et biophysica acta, 1968, Jul-23, Volume: 161, Issue:2

    Topics: Animals; Chromosomes; Culture Techniques; Cytarabine; Cytosine Nucleotides; Depression, Chemical; Hydrogen-Ion Concentration; Leukemia; Leukemia Virus, Murine; Leukemia, Experimental; Mice; Mutation; Nucleosides; Nucleotides; Solubility; Staining and Labeling; Thymidine; Tritium; Uridine

1968
Sensitivity of human leukemic cells to anti-cancer agents in culture.
    Biochemical pharmacology, 1974, Feb-01, Volume: 23, Issue:3

    Topics: Animals; Antineoplastic Agents; Azauridine; Cells; Cells, Cultured; Chlorambucil; Culture Media; Cyclophosphamide; Cytarabine; Drug Resistance; Floxuridine; Horses; Humans; Leukemia, Experimental; Mercaptopurine; Methotrexate; Mice; Prednisone; Thioguanine; Vincristine

1974
Effectiveness of cytosine arabinoside therapy on leukemia (L-1210) of the central nervous system in mice arising during methotrexate treatment.
    Gan, 1968, Volume: 59, Issue:6

    Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Cytarabine; Leukemia, Experimental; Meninges; Methotrexate; Mice; Neoplasm Transplantation; Neoplasms, Nerve Tissue; Splenic Neoplasms

1968
Deoxycytidine kinase. I. Distribution in normal and neoplastic tissues and interrelationships of deoxycytidine and 1-beta-D-arabinofuranosylcytosine phosphorylation.
    Molecular pharmacology, 1969, Volume: 5, Issue:4

    Topics: Adenocarcinoma; Animals; Carcinoma, Hepatocellular; Cattle; Chick Embryo; Chromatography, Ion Exchange; Cytarabine; Cytosine Nucleotides; Deoxyuridine; Escherichia coli; Fibrosarcoma; Kinetics; Leukemia L1210; Leukemia, Experimental; Liver Neoplasms; Lymphoid Tissue; Mice; Mitosis; Neoplasms, Experimental; Nucleosides; Nucleotides; Phosphotransferases; Rats; Thymidine; Thymus Gland

1969
Spontaneous AK leukemia (lymphoma) as a model for human leukemias and lymphomas.
    Cancer chemotherapy reports. Part 3, 1972, Volume: 3, Issue:1

    Topics: Animals; Cyclophosphamide; Cytarabine; Disease Models, Animal; Drug Combinations; Leukemia Virus, Murine; Leukemia, Experimental; Lymphoma; Mice; Mice, Inbred Strains; Remission, Spontaneous; Thymectomy; Time Factors; Vincristine

1972
Effect of in vivo treatment with L-asparaginase on the in vitro uptake and phosphorylation of some antileukemic agents.
    Cancer research, 1974, Volume: 34, Issue:10

    Topics: Animals; Antimetabolites; Asparaginase; Biological Transport; Cytarabine; Dose-Response Relationship, Drug; Fluorouracil; Leucine; Leukemia, Experimental; Male; Mercaptopurine; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Oxidative Phosphorylation; Tetrahydrofolate Dehydrogenase; Time Factors

1974
The experimental antitumour properties of three congeners of the acridylmethanesulphonanilide (AMSA) series.
    European journal of cancer, 1974, Volume: 10, Issue:8

    Topics: Acridines; Animals; Anisoles; Antineoplastic Agents; Chemical Phenomena; Chemistry, Physical; Cytarabine; Dose-Response Relationship, Drug; Injections, Intradermal; Injections, Intraperitoneal; Injections, Intravenous; Injections, Subcutaneous; Leukemia L1210; Leukemia, Experimental; Mammary Neoplasms, Experimental; Melanoma; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Phenylenediamines; Skin Neoplasms; Structure-Activity Relationship; Sulfones

1974
Attempts at immunotherapy of 100 patients with acute lymphoid leukemia: some factors influencing results.
    National Cancer Institute monograph, 1972, Volume: 35

    Topics: Animals; Bone Marrow Examination; Central Nervous System; Corynebacterium; Cytarabine; Cytotoxicity Tests, Immunologic; Disease Models, Animal; Female; Humans; Immune Sera; Immunotherapy; Leukemia, Experimental; Leukemia, Lymphoid; Lymphocyte Activation; Male; Methotrexate; Mice; Mice, Inbred AKR; Remission, Spontaneous

1972
The rate of mutation of L5178Y asparagine-dependent mouse leukemia cells to asparagine independence and its biological consequences.
    Cancer research, 1973, Volume: 33, Issue:7

    Topics: Animals; Asparagine; Carbon Isotopes; Cell Division; Cell Line; Cytarabine; Disease Models, Animal; Genes; Leukemia, Experimental; Leukemia, Lymphoid; Mice; Mutation; Phenotype; Time Factors

1973
Comparative chemotherapy of AKR lymphoma and human hematological neoplasia.
    Cancer research, 1974, Volume: 34, Issue:1

    Topics: Animals; Antineoplastic Agents; Biological Assay; Carmustine; Cyclohexanes; Cyclophosphamide; Cytarabine; Daunorubicin; Disease Models, Animal; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Fluorouracil; Hodgkin Disease; Humans; Leukemia; Leukemia L1210; Leukemia, Experimental; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma; Male; Mechlorethamine; Melphalan; Mice; Mice, Inbred AKR; Multiple Myeloma; Nitrosourea Compounds; Prednisone; Remission, Spontaneous; Vinblastine; Vincristine

1974
Pharmacologic and cytokinetic studies of arabinosyl cytosine.
    Bibliotheca haematologica, 1973, Volume: 39

    Topics: Adolescent; Adult; Animals; Antibody Formation; Cell Migration Inhibition; Child; Child, Preschool; Cyclophosphamide; Cytarabine; DNA; DNA Nucleotidyltransferases; Drug Therapy, Combination; Humans; Leukemia, Experimental; Leukemia, Myeloid, Acute; Lymphocyte Activation; Macrophages; Mice; Mitosis; Multiple Myeloma; Prednisone; Vincristine

1973
Different blocks in the differentiation of myeloid leukemic cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1974, Volume: 71, Issue:9

    Topics: Animals; Binding Sites, Antibody; Blood; Cell Differentiation; Cell Membrane; Cells, Cultured; Complement System Proteins; Cytarabine; Dactinomycin; Endotoxins; Erythrocytes; Granulocytes; Immune Adherence Reaction; Immunoglobulins; Leukemia, Experimental; Leukemia, Myeloid; Leukocytes; Macrophages; Mice; Prednisolone; Sheep; Uracil

1974
Pharmacology of 3,5-diamino-1,24-triazole (guanazole). 1. Antitumor activity of guanazole.
    Journal of the National Cancer Institute, 1972, Volume: 48, Issue:3

    Topics: Amines; Animals; Antineoplastic Agents; Carcinoma 256, Walker; Cyclophosphamide; Cytarabine; Depression, Chemical; Female; Hydroxyurea; In Vitro Techniques; Leukemia L1210; Leukemia, Experimental; Lymphoma, Large B-Cell, Diffuse; Male; Mast-Cell Sarcoma; Methotrexate; Mice; Neoplasms, Experimental; Nitrosourea Compounds; Plasmacytoma; Structure-Activity Relationship; Triazoles

1972
Relationship between white blood cell count and diagnosis and therapeutic response in AKR mice with spontaneous leukemia (lymphoma).
    Cancer chemotherapy reports, 1972, Volume: 56, Issue:6

    Topics: Animals; Cyclophosphamide; Cytarabine; Female; Leukemia, Experimental; Leukocyte Count; Leukocytes; Liver; Male; Mice; Mice, Inbred AKR; Organ Size; Spleen; Thymus Gland; Time Factors

1972
Combination chemotherapy with cytosine arabinoside, L-asparaginase, and 6-azauridine for transplantable murine leukemias.
    Cancer research, 1973, Volume: 33, Issue:4

    Topics: Animals; Asparaginase; Azauridine; Cytarabine; Drug Synergism; Female; Leukemia L1210; Leukemia, Experimental; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Transplantation; Transplantation, Homologous

1973
Enhancement of the antiproliferative action of 1- -D-arabinofuranosylcytosine by methotrexate in murine leukemic cells (L5178Y).
    Cancer research, 1973, Volume: 33, Issue:3

    Topics: Animals; Cell Survival; Cells, Cultured; Clone Cells; Cytarabine; Drug Synergism; Furans; Hypoxanthines; Leukemia, Experimental; Methotrexate; Mice; Mitosis; Phosphates; Serine; Time Factors; Tritium

1973
Heterocyclic thiosemicarbazones and related derivatives. Synthesis and screening data.
    Journal of medicinal chemistry, 1973, Volume: 16, Issue:9

    Topics: Animals; Antineoplastic Agents; Cytarabine; Drug Resistance; Leukemia L1210; Leukemia, Experimental; Mercaptopurine; Mice; Purines; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Thiosemicarbazones; Vincristine

1973
Perturbation of leukemic cell population in AKR mice due to chemotherapy.
    Cancer research, 1973, Volume: 33, Issue:11

    Topics: Animals; Cell Count; Cell Division; Cell Survival; Cytarabine; Leukemia, Experimental; Lymph Nodes; Mice; Mice, Inbred AKR; Organ Size; Spleen; Thymus Gland; Time Factors

1973
Effect of phosphorylated cyclocytidine on deoxyribonucleic acid polymerase.
    Biochemical pharmacology, 1973, Nov-15, Volume: 22, Issue:22

    Topics: Anhydrides; Animals; Antineoplastic Agents; Carbon Radioisotopes; Cytarabine; Cytosine Nucleotides; DNA Nucleotidyltransferases; DNA, Neoplasm; Leukemia L1210; Leukemia, Experimental; Male; Mice; Nucleosides; Phosphotransferases; Thymidine; Tritium

1973
Antitumor activity of cyclocytidine derivatives.
    Gan, 1973, Volume: 64, Issue:5

    Topics: Anhydrides; Animals; Antineoplastic Agents; Cytarabine; Leukemia, Experimental; Male; Mice; Structure-Activity Relationship

1973
Composition of leukemic cell populations in AKR leukemia and effects of chemotherapy.
    European journal of cancer, 1973, Volume: 9, Issue:8

    Topics: Animals; Autoradiography; Cell Count; Cell Division; Cell Separation; Cyclophosphamide; Cytarabine; Leukemia, Experimental; Mice; Mice, Inbred AKR; Nitrosourea Compounds; Prednisolone; Thymus Gland; Tritium; Vincristine

1973
Combination radiotherapy and chemotherapy for P388 lymphocytic leukemia in vivo.
    Cancer chemotherapy reports. Part 2, 1974, Volume: 4, Issue:1

    Topics: Alanine; Animals; Cisplatin; Cobalt Radioisotopes; Cyclophosphamide; Cytarabine; Female; Fluorouracil; Leukemia, Experimental; Leukemia, Lymphoid; Male; Mechlorethamine; Methotrexate; Mice; Neoplasm Transplantation; Prednisone; Procarbazine; Prognosis; Radioisotope Teletherapy; Radiotherapy Dosage; Transplantation, Homologous; Vinblastine; Vincristine

1974
Current studies on the therapy of experimental leukemia.
    Bibliotheca haematologica, 1970, Issue:36

    Topics: Alkylating Agents; Animals; Antibodies, Viral; Cytarabine; Dactinomycin; Friend murine leukemia virus; Glycine; Leukemia, Experimental; Lymphoma, Large B-Cell, Diffuse; Mercaptopurine; Mice; Mice, Inbred BALB C; Moloney murine leukemia virus; Nitrogen Mustard Compounds; Poly I-C; Porfiromycin; Purines; Pyrans; Rauscher Virus; Remission, Spontaneous; Spleen; Vincristine; Virus Replication

1970
Collateral sensitivity of resistant lines of mouse leukemias L1210 and L5178Y.
    Cancer research, 1972, Volume: 32, Issue:4

    Topics: Animals; Antineoplastic Agents; Azirines; Cell Line; Cyclophosphamide; Cytarabine; Cytogenetics; Drug Resistance; Female; Leukemia L1210; Leukemia, Experimental; Mercaptopurine; Methotrexate; Mice; Mice, Inbred Strains; Transplantation, Heterologous; Transplantation, Homologous

1972
Cell proliferation and the differential response of normal and malignant tissues. Silvanus Thompson Memorial Lecture.
    The British journal of radiology, 1972, Volume: 45, Issue:531

    Topics: Animals; Blood Vessels; Busulfan; Cell Survival; Cyclophosphamide; Cytarabine; Diffusion; Epithelial Cells; Epithelium; Fibrosarcoma; Hematopoietic Stem Cells; Intestine, Small; Leukemia L1210; Leukemia, Experimental; Methotrexate; Mice; Mitosis; Necrosis; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms; Oxygen; Radiation Effects; Rats

1972
Antitumor activity of cyclocytidine in a variety of tumors.
    Gan, 1972, Volume: 63, Issue:3

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cell Line; Cyclization; Cyclophosphamide; Cytarabine; Cytidine; Dose-Response Relationship, Drug; Female; Fluorouracil; Leukemia L1210; Leukemia, Experimental; Male; Mercaptopurine; Methotrexate; Mice; Mitomycins; Neoplasms, Experimental; Sarcoma 180

1972
Induction and characteristics of resistance to L-asparaginase (NSC-109229) in mouse leukemia L5178Y.
    Cancer chemotherapy reports, 1971, Volume: 55, Issue:2

    Topics: Amino Acids; Animals; Asparaginase; Azaserine; Body Weight; Cytarabine; Drug Resistance; Female; Leukemia, Experimental; Male; Methotrexate; Mice; Neoplasm Transplantation; Time Factors

1971
Incorporation of arabinosyl cytosine into 2-7S ribonucleic acid and cell death.
    Biochemical pharmacology, 1971, Volume: 20, Issue:8

    Topics: Acrylamides; Animals; Cell Line; Cell Survival; Cells, Cultured; Centrifugation, Density Gradient; Cytarabine; In Vitro Techniques; Leukemia, Experimental; Mice; RNA, Neoplasm; Tritium; Uridine

1971
Predictive tests in culture of drug-resistant mutants selected in vivo.
    National Cancer Institute monograph, 1971, Volume: 34

    Topics: Animals; Antineoplastic Agents; Biological Assay; Cell Line; Clone Cells; Cytarabine; Drug Resistance; Idoxuridine; Leukemia, Experimental; Methods; Methotrexate; Mice; Mice, Inbred Strains; Molecular Biology; Mutagens; Mutation; Prognosis

1971
Experimental leukaemia chemotherapy: a perspective.
    The New Zealand medical journal, 1970, Volume: 72, Issue:458

    Topics: Animals; Cyclophosphamide; Cytarabine; Leukemia, Experimental; Mice

1970
Experimental studies with L-asparaginase in mouse leukemias.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1970, Volume: 33

    Topics: Animals; Antibiotics, Antineoplastic; Asparaginase; Asparagine; Carmustine; Cell Line; Child, Preschool; Cytarabine; Dactinomycin; Drug Resistance; Drug Synergism; Female; Half-Life; Humans; Leukemia, Experimental; Leukemia, Lymphoid; Mice; Neoplasm Proteins; Podophyllin; Pyridines; Stereoisomerism; Thioguanine; Thiosemicarbazones; Time Factors; Tritium; Valine

1970
Response to therapy of spontaneous, first passage, and long passage lines of AK leukemia.
    Cancer chemotherapy reports, 1969, Volume: 53, Issue:6

    Topics: Age Factors; Animals; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Leukemia L1210; Leukemia, Experimental; Lymphoma; Mice; Time Factors; Vincristine

1969
Studies on the mechanism of action of 1-beta-D-arabinofuranosylcytosine as an inhibitor of DNA synthesis in human leukemic leukocytes.
    Cancer research, 1969, Volume: 29, Issue:12

    Topics: Animals; Binding Sites; Cytarabine; DNA Nucleotidyltransferases; DNA, Neoplasm; Humans; Hydroxyurea; In Vitro Techniques; Leukemia, Experimental; Leukocytes; Tritium; Uridine

1969
Antitumor effect and mode of action of 1-beta-D-arabinofuranosylcytosine 5'-phosphate in leukemia L1210.
    Cancer research, 1968, Volume: 28, Issue:4

    Topics: Animals; Antineoplastic Agents; Biological Transport, Active; Carbon Isotopes; Cytarabine; Leukemia L1210; Leukemia, Experimental; Male; Mice; N-Glycosyl Hydrolases

1968
Effects of cytosine arabinoside on the cell viability and uptake of deoxypyrimidine nucleosides in L5178Y cells.
    Biochemical pharmacology, 1968, Volume: 17, Issue:5

    Topics: Animals; Culture Techniques; Cytarabine; Depression, Chemical; DNA, Neoplasm; Leukemia, Experimental; Lymphocytes; Methotrexate; Mice; Nucleosides; Phosphates; RNA, Neoplasm; Thymidine; Tritium

1968
The incorporation of 3H-cytosine arabinoside and its effect on murine leukemic cells (L5178Y).
    Biochemical pharmacology, 1968, Volume: 17, Issue:5

    Topics: Animals; Cell Division; Chromatography, Ion Exchange; Chromatography, Paper; Culture Techniques; Cytarabine; Cytosine Nucleotides; Depression, Chemical; DNA, Neoplasm; Leukemia, Experimental; Mice; Nucleosides; RNA, Neoplasm; Solubility; Time Factors; Tritium

1968
Nucleic acids. X. Enzymatic hydrolysis of dinucleoside phosphates containing ara-cytidine (cytarabine).
    Biochemical pharmacology, 1969, Volume: 18, Issue:4

    Topics: Animals; Antiviral Agents; Carcinoma, Squamous Cell; Cytarabine; Esterases; Esters; Humans; Kidney; Leukemia, Experimental; Liver; Mice; Nucleosides; Phosphates; Rabbits; Thymidine

1969
Activity of cytosine arabinoside (NSC-63878) in a spectrum of rodent tumors.
    Cancer chemotherapy reports, 1965, Volume: 47

    Topics: Animals; Cytarabine; In Vitro Techniques; Leukemia, Experimental; Mice; Neoplasms, Experimental; Rats

1965
Comparative activity of 1-beta-d-arabinofuranosyl-5-fluorocytosine and related compounds against transplanted mouse leukemias in vivo and in vitro.
    Cancer research, 1966, Volume: 26, Issue:3

    Topics: Animals; Antineoplastic Agents; Cytarabine; In Vitro Techniques; Leukemia, Experimental; Mice; Nucleosides

1966