cytarabine and Down Syndrome

cytarabine has been researched along with Down Syndrome in 80 studies

Research

Studies (80)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (6.25)	18.7374
1990's	18 (22.50)	18.2507
2000's	30 (37.50)	29.6817
2010's	24 (30.00)	24.3611
2020's	3 (3.75)	2.80

Authors

Authors	Studies
Al-Antary, ET; Edwards, H; Ge, Y; Gupte, A; Ravindranath, Y; Taub, JW	1
Fujiwara, K; Ishida, H; Kanamitsu, K; Nishida, K; Noda, T; Ochi, M; Tamai, K; Tamefusa, K; Tsukahara, H; Washio, K; Washio, Y; Yoshimoto, J	1
Alonzo, T; Beckman, A; Berman, JN; Brodersen, L; Chisholm, K; Druley, T; Gamis, A; Gerbing, R; Heerema-McKenney, A; Hijiya, N; Hirsch, B; Hitzler, J; Kolb, EA; Loken, M; O'Brien, M; Raimondi, S; Schore, R; Taub, J; Tong, S; Viola, S; Wang, YC	1
Alonzo, TA; Berman, JN; Campana, D; Coustan-Smith, E; Gamis, AS; Ge, Y; Gerbing, RB; Head, D; Hirsch, B; Hitzler, JK; Lacayo, NJ; Mast, K; Mathew, P; Raimondi, S; Sorrell, AD; Taub, JW; Wang, YC	1
Shand, JC	1
Becktell, K; Burke, MJ; Houser, K	1
Bhatnagar, N; Greenough, A; James, B; Norton, A; O'Marcaigh, AS; Roberts, I; Tunstall, O; Vyas, P; Watts, T; Wright, M	1
Creutzig, U; de Haas, V; Flasinski, M; Klusmann, JH; Reinhardt, D; Reinhardt, K; Scheibke, K; van der Velden, VHJ; Verwer, F; von Neuhoff, C; Zimmermann, M; Zwaan, CM	1
Okamura, T; Shimada, A; Tani, K; Tsukahara, H; Washio, Y; Yoshimoto, J	1
Geerlinks, A; Hitzler, J; Keis, J; Ngan, B; Shammas, A; Vali, R	1
Buck, SA; Caldwell, JT; Edwards, H; Ge, Y; Taub, JW	1
Caldwell, JT; Ge, Y; Taub, JW	1
Adachi, S; Goto, H; Horibe, K; Ito, E; Iwamoto, S; Kinoshita, A; Koh, K; Kudo, K; Moritake, H; Nakahata, T; Nakayama, H; Saito, AM; Shimada, A; Taga, T; Takahashi, H; Taki, T; Tawa, A; Terui, K; Toki, T; Tomizawa, D; Watanabe, T	1
Bochennek, K; Creutzig, U; Gilfert, J; Hassler, A; Lehrnbecher, T; Perner, C; Reinhardt, D; Schöning, S	1
Bradshaw, WT; Rhoderick, JA	1
Kassam, A; Mandel, K	1
Campana, D; Crews, KR; Downing, JR; Gandhi, VV; Pounds, S; Pui, CH; Raimondi, SC; Razzouk, BI; Ribeiro, RC; Rubnitz, JE; Yang, S	1
Abe, D; Adachi, S; Asai, K; Daifu, T; Izawa, K; Kato, I; Matubara, H; Nakahata, T; Tokumasu, M; Umeda, K; Uryu, K; Watanabe, K	1
Britt-Marie, F; Curt, P; Frost, BM; Gudmar, L; Hasle, H; Hellebostad, M; Henrik, H; Josefine, P; Jukka, K; Kanerva, J; Kjeld, S; Lönnerholm, G; Marit, H; Palle, J; Petersson, C; Schmiegelow, K	1
Bessho, F; Hama, A; Ishii, R; Kinoshita, A; Kobayashi, N; Kojima, S; Kudo, K; Morimoto, A; Okimoto, Y; Sunami, S; Tawa, A; Tsukimoto, I	1
Baruchel, A; Clavel, J; Nacka, F; Pérel, Y; Tandonnet, J	1
Abe, M; Arai, J; Katayama, N; Kato, K; Kobayashi, C; Koike, K; Mouri, Y; Shiono, J; Tsuchida, M; Yanase, K; Yoshimi, A	1
Ravindranath, Y; Taub, JW	2
Higa, T; Horikoshi, Y; Itoh, M; Iwai, A; Kanegane, H; Kogawa, K; Ogawa, A; Okada, M; Saiwakawa, Y; Shimomura, Y; Taga, T; Tsurusawa, M; Ueyama, J; Watanabe, A; Yamanaka, J	1
Hirabayashi, K; Ishii, E; Koike, K; Nakamura, T; Saito, S; Sakashita, K; Shiohara, M; Takahashi, D; Tanaka, M; Yanagisawa, R	1
Alonzo, TA; Arceci, RJ; Barnard, D; Doyle, J; Gamis, AS; Gerbing, RB; Hilden, JM; Loew, TW; Massey, G; Perentesis, J; Ravindranath, Y; Sharma, M; Smith, FO; Sorrell, AD; Taub, J	1
Balci, TB; Berman, JN; Buck, SA; Dellaire, G; Dombkowski, AA; Edwards, H; Ge, Y; Matherly, LH; Taub, JW; Xavier, AC; Xie, C	1
Hidaka, T; Koga, H; Miyako, K; Suga, N; Takahashi, N	1
Roberts, I; Vyas, P	1
Kimoto, Y; Moritake, H; Nunoi, H; Sawa, D; Shimonodan, H; Yamada, A	1
Alonzo, TA; Arceci, RJ; Barnard, D; Gamis, AS; Gerbing, RB; Hathaway, L; Hilden, JM; Loew, TW; Ravindranath, Y; Smith, FO; Sorrell, AD; Taub, JW; Woods, WG	1
Creutzig, U; Klusmann, JH; Kolenova, A; Neuhoff, C; Pekrun, A; Reinhardt, D; Reinhardt, K; Rössig, C; Sander, A; Sauerbrey, A; von Stackelberg, A	1
Ge, Y; Jensen, TL; Matherly, LH; Taub, JW	1
Creutzig, U; Kaiser, J; Klingebiel, T; Lehrnbecher, T; Reinhardt, D; Varwig, D	1
Abhyankar, D; Advani, S; Amare Kadam, P; Baisane, C; Bakshi, C; Banavali, S	1
Flatley, RM; Ge, Y; Grohar, PJ; Jensen, TL; Matherly, LH; Ravindranath, Y; Stout, ML; Taub, JW	1
Dormann, S; Hentschel, R; Kontny, U; Krüger, M; Niemeyer, C; Rasenack, R; Strahm, B	1
Buck, S; Ge, Y; Jensen, TL; Matherly, LH; Ravindranath, Y; Stout, ML; Tatman, DA; Taub, JW; Thomas, RL	1
Bradbury, J	1
Creutzig, U; Diekamp, S; Dworzak, M; Reinhardt, D; Stary, J; Zimmermann, M	1
Becton, D; Camitta, B; Carroll, A; Chang, M; Civin, C; Dahl, G; Raimondi, SC; Ravindranath, Y; Steuber, CP; Weinstein, HJ	1
Hasle, H; Hokland, P; Lund, B; Nyvold, CG; Østergaard, M	1
Becton, DL; Buck, SA; Dombkowski, AA; Ge, Y; LaFiura, KM; Massey, G; Matherly, LH; Ravindranath, Y; Stout, ML; Tatman, D; Taub, JW; Weinstein, HJ; Yedidi, RS	1
Hatakeyama, N; Hori, T; Kuroiwa, Y; Mizue, N; Suzuki, N; Yamamoto, M	1
de Graaf, SS; Gibson, BE; Hann, IM; Hills, RK; O'Marcaigh, A; Rao, A; Stiller, C; Webb, DK; Wheatley, K	1
Abildgaard, L; Abrahamsson, J; Ellebaek, E; Gustafsson, G; Hasle, H; Hovi, L; Jonmundsson, G; Zeller, B	1
Al-Ahmari, A; Hitzler, J; Shah, N; Sung, L; Zipursky, A	1
Hanada, R; Kigasawa, H; Kinoshita, A; Tabuchi, K; Tomizawa, D; Tsuchida, M; Tsukimoto, I	1
Becton, DL; Buck, S; Chang, M; Raimondi, SC; Ravindranath, Y; Savaşan, S; Weinstein, H	1
Alghzaly, AA; Alkindi, S; Muralitharan, S; Pathare, AV; Raeburn, JA; Udayakumar, AM	1
Hamamoto, K; Hanada, R; Horibe, K; Imaizumi, M; Kigasawa, H; Kobayashi, R; Kojima, S; Kudo, K; Morimoto, A; Nakayama, H; Tabuchi, K; Tawa, A; Tsuchida, M; Tsukimoto, I; Yabe, H	1
Buck, SA; Chen, Q; Diakiw, AE; Dombkowski, AA; Ge, Y; LaFiura, KM; Matherly, LH; Payton, SG; Salagrama, S; Taub, JW	1
Preston, RJ	1
Lehmann, AR; Parshad, R; Price, FM; Sanford, KK; Tarone, RE	1
Parshad, R; Price, FM; Sanford, KK; Schapiro, MB; Tarone, RE	1
Grønn, M; Holte, H; Lie, SO; Seip, M; Slørdahl, SH; Smeland, EB	1
Bernaudin, F; Boccara, JF; Denavit, MF; Dommergues, JP; Lejeune, F; Tchernia, G	1
Chen, PM; Chiou, TJ; Fan, FS; Hsieh, RK; Liu, JH; Tzeng, CH; Wei, CH; Yu, IT	1
Buck, SA; Gurney, JG; Matherly, LH; Ravindranath, Y; Stout, ML; Taub, JW	1
Conter, V; D'Angelo, P; Dampier, C; Jankovic, M; Johnson, FL; Masera, G; Rizzari, C	1
Melnick, LK; Nee, LE; Parshad, RP; Price, FM; Robbins, JH; Sanford, KK; Schapiro, MB; Tarone, RE	1
Becton, DL; Buck, SA; Huang, X; Ravindranath, Y; Stout, ML; Taub, JW; Vega, RA	1
Alfaro, E; Casak, S; Cygler, A; Felice, MS; Fraquelli, L; Gallego, M; Pérez, LE; Quinteros, R; Sackmann-Muriel, F; Zubizarreta, P	1
Parshad, R; Price, FM; Sanford, KK; Schapiro, MB	1
Readett, D; Richards, M; Vora, AJ; Watmore, A; Welch, J	1
Conter, V; Dell'Orto, M; Ferrari, E; Jankovic, M; Malberti, R; Milani, M; Rizzari, C	1
Becton, DL; Buck, SA; Chang, MN; Huang, X; Massey, GV; Matherly, LH; Ravindranath, Y; Stout, ML; Taub, JW; Weinstein, HJ	1
Akiyama, Y; Eguchi, M; Hayashi, Y; Hosoi, G; Ishii, E; Kato, K; Koike, K; Kojima, S; Nishimura, S; Ohara, A; Okamura, J; Okimoto, Y; Sako, M; Sato, T; Tsukimoto, I; Ueda, K; Yazaki, M; Yoshikawa, T	1
Frost, BM; Gustafsson, G; Larsson, R; Lönnerholm, G; Nygren, P	1
Lange, B	1
Dutcher, JA; Ge, Y; Huang, X; Matherly, LH; Mohammad, RM; Ravindranath, Y; Stout, ML; Taub, JW	1
Creutzig, U; de Vries, E; Hählen, K; Huismans, DR; Janka-Schaub, GE; Jansen, G; Kaspers, GJ; Peters, GJ; Pieters, R; Rots, MG; van Zantwijk, CH; Veerman, AJ; Zwaan, CM	1
Abella, E; Alvarado, CS; Chauvenet, A; Dubowy, R; Harris, M; Inoue, S; Krischer, JP; Ravindranath, Y; Ritchey, AK; Wiley, J	1
Balcar-Boroń, A; Graduszewska-Czerebiej, K; Nowaczyk-Michalak, A	1
Berglund, G; Gustafsson, G; Jonmundsson, G; Lie, SO; Siimes, M; Yssing, M	1
Brecher, ML; Freeman, AI; Green, DM; Sandberg, AA; Simon, JH; Tebbi, CK	1
Boutard, P; Guihard, J; Reman, O	1
Levy, JM; Lutz, P; Seiller, F; Stoll, C	1
Clarkson, B; Fried, J; Okita, T; Ota, K; Sakai, Y; Strife, A	1

Reviews

6 review(s) available for cytarabine and Down Syndrome

Article	Year
The paradox of Myeloid Leukemia associated with Down syndrome. Biochemical pharmacology, 2022, Volume: 201 Topics: Child; Cytarabine; Down Syndrome; GATA1 Transcription Factor; Humans; Leukemia, Myeloid, Acute; Leukemoid Reaction	2022
Prognosis and management of acute myeloid leukemia in patients with Down syndrome. Expert review of hematology, 2014, Volume: 7, Issue:6 Topics: Antimetabolites, Antineoplastic; Bone Marrow Transplantation; Child; Cytarabine; Down Syndrome; GATA1 Transcription Factor; Humans; Leukemia, Myeloid, Acute; Prognosis	2014
Optimal treatment intensity in children with Down syndrome and myeloid leukaemia: data from 56 children treated on NOPHO-AML protocols and a review of the literature. Annals of hematology, 2006, Volume: 85, Issue:5 Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Cytarabine; Disease-Free Survival; Down Syndrome; Humans; Leukemia, Myeloid; Male; Remission Induction; Retrospective Studies; Survival Rate	2006
Down syndrome and acute myeloid leukemia. Lessons learned from experience with high-dose Ara-C containing regimens. Advances in experimental medicine and biology, 1999, Volume: 457 Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Deoxycytosine Nucleotides; Disease-Free Survival; Dose-Response Relationship, Drug; Down Syndrome; Humans; Leukemia, Myeloid, Acute	1999
The management of neoplastic disorders of haematopoiesis in children with Down's syndrome. British journal of haematology, 2000, Volume: 110, Issue:3 Topics: Acute Disease; Adolescent; Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cytarabine; Daunorubicin; Disease-Free Survival; Down Syndrome; Female; Genetic Predisposition to Disease; Humans; Infant; Infant, Newborn; Leukemia; Leukemia, Myeloid; Male; Maternal Age; Myeloproliferative Disorders; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Vincristine	2000
Acute megakaryoblastic leukemia associated with mosaic Down's syndrome. Cancer, 1987, Nov-15, Volume: 60, Issue:10 Topics: Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 17; Clone Cells; Cyclophosphamide; Cytarabine; Down Syndrome; Doxorubicin; Etoposide; Female; Humans; Hydrocortisone; Infant; Leukemia, Megakaryoblastic, Acute; Methotrexate; Mosaicism; Prednisone; Thioguanine; Trisomy	1987

Trials

17 trial(s) available for cytarabine and Down Syndrome

Article	Year
High-dose AraC is essential for the treatment of ML-DS independent of postinduction MRD: results of the COG AAML1531 trial. Blood, 2021, 12-09, Volume: 138, Issue:23 Topics: Antimetabolites, Antineoplastic; Child, Preschool; Cytarabine; Dose-Response Relationship, Drug; Down Syndrome; Female; Humans; Infant; Leukemia, Myeloid; Male; Neoplasm, Residual; Prognosis; Treatment Outcome	2021
Improved outcomes for myeloid leukemia of Down syndrome: a report from the Children's Oncology Group AAML0431 trial. Blood, 2017, 06-22, Volume: 129, Issue:25 Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Cytarabine; Cytogenetic Analysis; Daunorubicin; Disease-Free Survival; Down Syndrome; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Myelodysplastic Syndromes; Neoplasm, Residual; Treatment Outcome	2017
Low-dose cytarabine to prevent myeloid leukemia in children with Down syndrome: TMD Prevention 2007 study. Blood advances, 2018, 07-10, Volume: 2, Issue:13 Topics: Cytarabine; Disease Progression; Down Syndrome; Historically Controlled Study; Humans; Infant; Infant, Newborn; Leukemia, Myeloid; Leukemoid Reaction; Neoplasm, Residual; Survival Analysis	2018
Preserved High Probability of Overall Survival with Significant Reduction of Chemotherapy for Myeloid Leukemia in Down Syndrome: A Nationwide Prospective Study in Japan. Pediatric blood & cancer, 2016, Volume: 63, Issue:2 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Disease-Free Survival; Down Syndrome; Doxorubicin; Etoposide; Female; Humans; Induction Chemotherapy; Infant; Japan; Kaplan-Meier Estimate; Leukemia, Myeloid; Male; Prospective Studies	2016
Infectious Complications in Children With Acute Myeloid Leukemia and Down Syndrome: Analysis of the Prospective Multicenter Trial AML-BFM 2004. Pediatric blood & cancer, 2016, Volume: 63, Issue:6 Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Down Syndrome; Etoposide; Female; Humans; Idarubicin; Infant; Infections; Leukemia, Myeloid, Acute; Male; Mitoxantrone	2016
Combination of cladribine and cytarabine is effective for childhood acute myeloid leukemia: results of the St Jude AML97 trial. Leukemia, 2009, Volume: 23, Issue:8 Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cladribine; Combined Modality Therapy; Cytarabine; Daunorubicin; Down Syndrome; Drug Administration Schedule; Etoposide; Hematopoietic Stem Cell Transplantation; Humans; Infant; Kaplan-Meier Estimate; Leukemia, Myeloid; Myelodysplastic Syndromes; Prognosis; Proportional Hazards Models; Remission Induction; Young Adult	2009
Thioguanine pharmacokinetics in induction therapy of children with acute myeloid leukemia. Anti-cancer drugs, 2009, Volume: 20, Issue:1 Topics: Administration, Oral; Adolescent; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Down Syndrome; Doxorubicin; Drug Administration Schedule; Drug Monitoring; Erythrocytes; Etoposide; Female; Guanine Nucleotides; Humans; Infant; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Registries; Scandinavian and Nordic Countries; Thioguanine; Thionucleotides; Treatment Outcome	2009
Continuous and high-dose cytarabine combined chemotherapy in children with down syndrome and acute myeloid leukemia: Report from the Japanese children's cancer and leukemia study group (JCCLSG) AML 9805 down study. Pediatric blood & cancer, 2011, Jul-15, Volume: 57, Issue:1 Topics: Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Cytarabine; Disease-Free Survival; Down Syndrome; Doxorubicin; Female; Humans; Infant; Infant, Newborn; Japan; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Survival Rate; Vincristine	2011
Natural history of transient myeloproliferative disorder clinically diagnosed in Down syndrome neonates: a report from the Children's Oncology Group Study A2971. Blood, 2011, Dec-22, Volume: 118, Issue:26 Topics: Acute Disease; Antimetabolites, Antineoplastic; Cytarabine; Disease Progression; Down Syndrome; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Kaplan-Meier Estimate; Leukemia, Megakaryoblastic, Acute; Leukemia, Myeloid; Male; Myeloproliferative Disorders; Prognosis; Prospective Studies; Time Factors; Treatment Outcome	2011
Favorable survival maintained in children who have myeloid leukemia associated with Down syndrome using reduced-dose chemotherapy on Children's Oncology Group trial A2971: a report from the Children's Oncology Group. Cancer, 2012, Oct-01, Volume: 118, Issue:19 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Daunorubicin; Dexamethasone; Disease-Free Survival; Down Syndrome; Drug Administration Schedule; Etoposide; Female; Humans; Infant; Kaplan-Meier Estimate; Leukemia, Myeloid; Male; Thioguanine; Treatment Outcome	2012
AML patients with Down syndrome have a high cure rate with AML-BFM therapy with reduced dose intensity. Leukemia, 2005, Volume: 19, Issue:8 Topics: Adolescent; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Disease-Free Survival; Down Syndrome; Etoposide; Female; Humans; Idarubicin; Infant; Leukemia, Megakaryoblastic, Acute; Leukemia, Myeloid, Acute; Male; Survival Rate; Treatment Outcome	2005
Pediatric Oncology Group (POG) studies of acute myeloid leukemia (AML): a review of four consecutive childhood AML trials conducted between 1981 and 2000. Leukemia, 2005, Volume: 19, Issue:12 Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Antineoplastic Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Dose-Response Relationship, Drug; Down Syndrome; Follow-Up Studies; Humans; Infant; Infant, Newborn; Leukemia, Myeloid; Prognosis; Remission Induction; Survival Analysis; Treatment Outcome	2005
Treatment for myeloid leukaemia of Down syndrome: population-based experience in the UK and results from the Medical Research Council AML 10 and AML 12 trials. British journal of haematology, 2006, Volume: 132, Issue:5 Topics: Adolescent; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Cytogenetic Analysis; Daunorubicin; Down Syndrome; Drug Administration Schedule; Etoposide; Female; Humans; Infant; Leukemia, Myeloid; Leukocyte Count; Male; Mitoxantrone; Thioguanine; Treatment Outcome; United Kingdom	2006
Repetitive cycles of high-dose cytarabine are effective for childhood acute myeloid leukemia: long-term outcome of the children with AML treated on two consecutive trials of Tokyo Children's Cancer Study Group. Pediatric blood & cancer, 2007, Volume: 49, Issue:2 Topics: Acute Disease; Adolescent; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Down Syndrome; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Hydrocortisone; Infant; Infections; Japan; Kaplan-Meier Estimate; Leukemia, Myeloid; Male; Methotrexate; Mitoxantrone; Remission Induction; Survival Analysis; Transplantation, Autologous; Transplantation, Homologous; Treatment Outcome; Tretinoin; Vincristine	2007
Prospective study of a pirarubicin, intermediate-dose cytarabine, and etoposide regimen in children with Down syndrome and acute myeloid leukemia: the Japanese Childhood AML Cooperative Study Group. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Dec-01, Volume: 25, Issue:34 Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Disease-Free Survival; Down Syndrome; Doxorubicin; Etoposide; Female; Humans; Infant; Leukemia, Megakaryoblastic, Acute; Male; Prospective Studies; Treatment Outcome	2007
An effective chemotherapeutic regimen for acute myeloid leukemia and myelodysplastic syndrome in children with Down's syndrome. Leukemia, 2000, Volume: 14, Issue:5 Topics: Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Cytarabine; Daunorubicin; Disease-Free Survival; Down Syndrome; Etoposide; Female; Humans; Infant; Leukemia, Megakaryoblastic, Acute; Leukemia, Myeloid, Acute; Male; Myelodysplastic Syndromes; Probability; Remission Induction; Survival Rate; Time Factors; Treatment Outcome	2000
High-dose Ara-C as a single-agent consolidation therapy in childhood acute myelogenous leukemia. Haematology and blood transfusion, 1990, Volume: 33 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cross-Sectional Studies; Cytarabine; Down Syndrome; Doxorubicin; Humans; Iceland; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Life Tables; Multicenter Studies as Topic; Preleukemia; Remission Induction; Scandinavian and Nordic Countries; Survival Rate; Thioguanine	1990

Other Studies

57 other study(ies) available for cytarabine and Down Syndrome

Article	Year
Three Cases of Down Syndrome with Transient Abnormal Myelopoiesis who Underwent Liver Biopsy before Induction of Low-Dose Cytarabine. Acta medica Okayama, 2023, Volume: 77, Issue:2 Topics: Biopsy; Child; Cytarabine; Down Syndrome; Humans; Liver	2023
Looking up for AML in Down syndrome. Blood, 2017, 06-22, Volume: 129, Issue:25 Topics: Cytarabine; Down Syndrome; Etoposide; Humans; Leukemia, Myeloid, Acute	2017
Epigenetic Therapy in a Patient With Down Syndrome and Refractory Acute Myeloid Leukemia. Journal of pediatric hematology/oncology, 2019, Volume: 41, Issue:1 Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Decitabine; Down Syndrome; Granulocyte Colony-Stimulating Factor; Humans; Infant; Leukemia, Myeloid, Acute; Male; Vidarabine; Vorinostat	2019
Guidelines for the investigation and management of Transient Leukaemia of Down Syndrome. British journal of haematology, 2018, Volume: 182, Issue:2 Topics: Antimetabolites, Antineoplastic; Blood Cell Count; Cell Transformation, Neoplastic; Critical Illness; Cytarabine; DNA Mutational Analysis; Down Syndrome; Exchange Transfusion, Whole Blood; Female; Fetal Diseases; GATA1 Transcription Factor; Humans; Leukapheresis; Leukemoid Reaction; Liver Diseases; Mutation; Neoplasm, Residual; Pregnancy; Prenatal Diagnosis; Prognosis; Recurrence; Risk Factors	2018
Exchange Transfusion and Cytarabine for Transient Abnormal Myelopoiesis in Hydrops Fetalis. Acta medica Okayama, 2019, Volume: 73, Issue:2 Topics: Antimetabolites, Antineoplastic; Cytarabine; Down Syndrome; Exchange Transfusion, Whole Blood; Female; Humans; Hydrops Fetalis; Infant, Newborn; Male; Myelopoiesis	2019
Unusual lymphoid malignancy and treatment response in two children with Down syndrome. Pediatric blood & cancer, 2019, Volume: 66, Issue:9 Topics: Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Down Syndrome; Herpesvirus 4, Human; Humans; Male; Methotrexate; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; T-Lymphocytes	2019
Targeting the wee1 kinase for treatment of pediatric Down syndrome acute myeloid leukemia. Pediatric blood & cancer, 2014, Volume: 61, Issue:10 Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Child; Cytarabine; Down Syndrome; Drug Synergism; Flow Cytometry; Humans; Leukemia, Myeloid, Acute; Nuclear Proteins; Protein-Tyrosine Kinases; Pyrazoles; Pyrimidines; Pyrimidinones; Reverse Transcriptase Polymerase Chain Reaction	2014
Transient myeloproliferative disorder in a newborn with Down syndrome. Advances in neonatal care : official journal of the National Association of Neonatal Nurses, 2008, Volume: 8, Issue:4 Topics: Adult; Antimetabolites, Antineoplastic; Comorbidity; Cytarabine; Down Syndrome; Education, Nursing, Continuing; Fatal Outcome; Female; Humans; Infant, Newborn; Maternal Age; Myeloproliferative Disorders; Nursing Care; Pregnancy; Radiography; Risk Factors	2008
Chemotherapy induced esophageal stricture. Pediatric blood & cancer, 2009, Volume: 52, Issue:4 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Down Syndrome; Esophageal Stenosis; Esophagectomy; Humans; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Methotrexate; Tretinoin	2009
[Relapsed acute myeloid leukemia with Down syndrome showing long disease-free survival after bone marrow transplantation]. [Rinsho ketsueki] The Japanese journal of clinical hematology, 2009, Volume: 50, Issue:2 Topics: Adolescent; Antimetabolites, Antineoplastic; Bone Marrow Transplantation; Chromosomes, Human, Pair 7; Cytarabine; Disease-Free Survival; Down Syndrome; GATA1 Transcription Factor; Humans; Leukemia, Myeloid, Acute; Male; Monosomy; Mutation; Recurrence; Remission Induction; Risk; Time Factors	2009
Mosaic Down syndrome-associated acute myeloid leukemia does not require high-dose cytarabine treatment for induction and consolidation therapy. International journal of hematology, 2010, Volume: 91, Issue:4 Topics: Antimetabolites, Antineoplastic; Child, Preschool; Cytarabine; Disease-Free Survival; Dose-Response Relationship, Drug; Down Syndrome; Female; GATA1 Transcription Factor; Humans; Infant; Leukemia, Megakaryoblastic, Acute; Male; Mosaicism; Prevalence; Retrospective Studies; Survival Rate	2010
Myeloid leukaemia in children with Down syndrome: report of the registry-based French experience between 1990 and 2003. Pediatric blood & cancer, 2010, Jul-01, Volume: 54, Issue:7 Topics: Antineoplastic Agents; Child, Preschool; Cytarabine; Disease-Free Survival; Dose-Response Relationship, Drug; Down Syndrome; Female; France; Humans; Infant; Leukemia, Myeloid; Male; Registries; Treatment Outcome	2010
Transient abnormal myelopoiesis in a cytogenetically normal neonate. International journal of hematology, 2010, Volume: 92, Issue:3 Topics: Antineoplastic Agents; Cytarabine; Cytogenetic Analysis; Down Syndrome; Etoposide; Exons; GATA1 Transcription Factor; Humans; Infant, Newborn; Karyotyping; Mutation; Myelopoiesis; Myeloproliferative Disorders	2010
What's up with down syndrome and leukemia-A lot! Pediatric blood & cancer, 2011, Jul-15, Volume: 57, Issue:1 Topics: Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Cytarabine; Disease-Free Survival; Down Syndrome; Doxorubicin; Female; Humans; Infant; Infant, Newborn; Japan; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Survival Rate; Vincristine	2011
Retrospective analysis of risk factors for development of liver dysfunction in transient leukemia of Down syndrome. Leukemia & lymphoma, 2011, Volume: 52, Issue:8 Topics: Cytarabine; Disease Progression; Down Syndrome; Female; Hepatomegaly; Humans; Hyaluronic Acid; Immunosuppressive Agents; Infant; Infant, Newborn; Leukemia; Liver Cirrhosis; Liver Diseases; Male; Respiration Disorders; Retrospective Studies; Risk Factors; Splenomegaly	2011
A unique role of GATA1s in Down syndrome acute megakaryocytic leukemia biology and therapy. PloS one, 2011, Volume: 6, Issue:11 Topics: Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytarabine; Daunorubicin; Down Syndrome; Down-Regulation; Etoposide; GATA1 Transcription Factor; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Interleukin-1alpha; Lentivirus; Leukemia, Megakaryoblastic, Acute; Megakaryocytes; Proto-Oncogene Proteins c-bcl-2; RNA, Small Interfering	2011
Improving circulatory disturbance in transient abnormal myelopoiesis. Journal of pediatric hematology/oncology, 2012, Volume: 34, Issue:4 Topics: Antimetabolites, Antineoplastic; Blood Transfusion; Cytarabine; Down Syndrome; Fatal Outcome; GATA1 Transcription Factor; Humans; Hypertension, Pulmonary; Infant, Newborn; Infant, Newborn, Diseases; Liver Failure; Male; Mutation; Myelopoiesis; Renal Insufficiency	2012
Enigmatic variation. Blood, 2011, Dec-22, Volume: 118, Issue:26 Topics: Cytarabine; Down Syndrome; Female; Humans; Leukemia, Megakaryoblastic, Acute; Male; Myeloproliferative Disorders	2011
Acute megakaryoblastic leukemia and severe pulmonary fibrosis in a child with Down syndrome: successful treatment with ultra low-dose cytarabine using GATA1 mutation to monitor minimal residual disease. American journal of hematology, 2012, Volume: 87, Issue:4 Topics: Antimetabolites, Antineoplastic; Biomarkers; Biomarkers, Tumor; Cytarabine; Cytokines; Disease Progression; Down Syndrome; Drug Monitoring; Female; GATA1 Transcription Factor; Genetic Predisposition to Disease; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Leukemia, Megakaryoblastic, Acute; Mucin-1; Myeloproliferative Disorders; Neoplasm Proteins; Prednisone; Pulmonary Fibrosis; Remission Induction	2012
[GATA1-mutation associated leukemia in children with trisomy 21 mosaic]. Klinische Padiatrie, 2012, Volume: 224, Issue:3 Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Down Syndrome; Female; Follow-Up Studies; GATA1 Transcription Factor; Hematopoietic Stem Cell Transplantation; Humans; Infant; Infant, Newborn; Leukemia, Megakaryoblastic, Acute; Leukemia, Myeloid, Acute; Male; Mosaicism; Mutation; Myelopoiesis; Myeloproliferative Disorders	2012
Transcriptional regulation of the cystathionine-beta -synthase gene in Down syndrome and non-Down syndrome megakaryocytic leukemia cell lines. Blood, 2003, Feb-15, Volume: 101, Issue:4 Topics: Cystathionine beta-Synthase; Cytarabine; DNA; DNA-Binding Proteins; Down Syndrome; Gene Expression Regulation, Enzymologic; Humans; Leukemia, Megakaryoblastic, Acute; Luciferases; Mutagenesis, Site-Directed; Phosphorylation; Promoter Regions, Genetic; Sp1 Transcription Factor; Sp3 Transcription Factor; Transcription Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured	2003
Infectious complications in pediatric acute myeloid leukemia: analysis of the prospective multi-institutional clinical trial AML-BFM 93. Leukemia, 2004, Volume: 18, Issue:1 Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bacteremia; Bacteria; Child; Child, Preschool; Clinical Trials as Topic; Cytarabine; Down Syndrome; Etoposide; Female; Fever; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans; Infant; Infant, Newborn; Leukemia, Myeloid; Male; Mitoxantrone; Neutropenia; Prospective Studies; Retrospective Studies; Thioguanine	2004
Chromosomal rearrangement in Down syndrome with acute myeloid leukemia. Indian journal of pediatrics, 2003, Volume: 70, Issue:9 Topics: Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Chromosome Aberrations; Chromosome Deletion; Cytarabine; Daunorubicin; Down Syndrome; Female; Humans; Leukemia, Monocytic, Acute; Thioguanine; Translocation, Genetic	2003
The role of cytidine deaminase and GATA1 mutations in the increased cytosine arabinoside sensitivity of Down syndrome myeloblasts and leukemia cell lines. Cancer research, 2004, Jan-15, Volume: 64, Issue:2 Topics: Base Sequence; Cell Death; Cell Line, Tumor; Cells, Cultured; Cytarabine; Cytosine Deaminase; DNA Primers; DNA-Binding Proteins; Down Syndrome; Erythroid-Specific DNA-Binding Factors; Exons; GATA1 Transcription Factor; Humans; Introns; Leukemia; Molecular Sequence Data; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factors; Transcription, Genetic	2004
Life-threatening complications of transient abnormal myelopoiesis in neonates with Down syndrome. European journal of pediatrics, 2004, Volume: 163, Issue:7 Topics: Blood Cell Count; Blood Cells; Cytarabine; Down Syndrome; Female; Hematologic Diseases; Humans; Hydrops Fetalis; Immunosuppressive Agents; Infant, Newborn; Liver Cirrhosis; Male; Myelopoiesis; Respiratory Insufficiency; Treatment Outcome	2004
GATA1, cytidine deaminase, and the high cure rate of Down syndrome children with acute megakaryocytic leukemia. Journal of the National Cancer Institute, 2005, Feb-02, Volume: 97, Issue:3 Topics: Antimetabolites, Antineoplastic; Arabinofuranosylcytosine Triphosphate; Arabinofuranosyluracil; Blotting, Western; Child; Cytarabine; Cytidine Deaminase; DNA-Binding Proteins; Down Syndrome; Erythroid-Specific DNA-Binding Factors; GATA1 Transcription Factor; Humans; Leukemia, Megakaryoblastic, Acute; Polymerase Chain Reaction; Time Factors; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Up-Regulation	2005
High leukaemia cure rate in Down's syndrome explained. The Lancet. Oncology, 2005, Volume: 6, Issue:3 Topics: Cytarabine; DNA-Binding Proteins; Down Syndrome; Erythroid-Specific DNA-Binding Factors; Humans; Leukemia, Megakaryoblastic, Acute; Mutation; Transcription Factors	2005
WT1 gene expression in children with Down syndrome and transient myeloproliferative disorder. Leukemia research, 2006, Volume: 30, Issue:5 Topics: Acute Disease; Cytarabine; Down Syndrome; Female; Follow-Up Studies; GATA1 Transcription Factor; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Genes, Wilms Tumor; Humans; Infant, Newborn; Leukemia, Myeloid; Longitudinal Studies; Male; Mutation; Myeloproliferative Disorders; Reverse Transcriptase Polymerase Chain Reaction; Treatment Outcome	2006
Differential gene expression, GATA1 target genes, and the chemotherapy sensitivity of Down syndrome megakaryocytic leukemia. Blood, 2006, Feb-15, Volume: 107, Issue:4 Topics: Child; Cluster Analysis; Cytarabine; DNA Primers; Down Syndrome; GATA1 Transcription Factor; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Megakaryoblastic, Acute; Luciferases; Nucleic Acid Hybridization; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; Transfection; Tumor Cells, Cultured	2006
[Prognostic value of serum markers for liver fibrosis in transient abnormal myelopoiesis (TAM)]. [Rinsho ketsueki] The Japanese journal of clinical hematology, 2005, Volume: 46, Issue:11 Topics: Biomarkers; Blood Transfusion; Cytarabine; Down Syndrome; Humans; Hyaluronic Acid; Infant, Newborn; Liver Cirrhosis; Male; Myelopoiesis; Myeloproliferative Disorders; Peptide Fragments; Predictive Value of Tests; Procollagen; Retrospective Studies	2005
Long-term results of an ultra low-dose cytarabine-based regimen for the treatment of acute megakaryoblastic leukaemia in children with Down syndrome. British journal of haematology, 2006, Volume: 133, Issue:6 Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Diterpenes; Down Syndrome; Drug Administration Schedule; Epidemiologic Methods; Humans; Leukemia, Megakaryoblastic, Acute; Retinyl Esters; Treatment Outcome; Vincristine; Vitamin A	2006
CD36 (thrombospondin receptor) expression in childhood acute megakaryoblastic leukemia: in vitro drug sensitivity and outcome. Leukemia & lymphoma, 2006, Volume: 47, Issue:10 Topics: Adolescent; Adult; Biomarkers, Tumor; CD36 Antigens; Cell Membrane; Child; Child, Preschool; Cytarabine; Daunorubicin; Down Syndrome; Gene Expression Regulation, Neoplastic; Humans; Immunophenotyping; Infant; Infant, Newborn; Leukemia, Megakaryoblastic, Acute; Sensitivity and Specificity; Treatment Outcome	2006
Trisomy 21 as a sole acquired abnormality in an adult Omani patient with CD7- and CD9-positive acute myeloid leukemia. Archives of medical research, 2007, Volume: 38, Issue:7 Topics: Adult; Antigens, CD; Antigens, CD7; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Cytogenetic Analysis; Daunorubicin; Down Syndrome; Humans; Karyotyping; Leukemia, Myeloid, Acute; Male; Membrane Glycoproteins; Remission Induction; Tetraspanin 29; Treatment Outcome	2007
The role of the proto-oncogene ETS2 in acute megakaryocytic leukemia biology and therapy. Leukemia, 2008, Volume: 22, Issue:3 Topics: Acute Disease; Cell Differentiation; Child; Chromosomes, Human, Pair 21; Cytarabine; Daunorubicin; Down Syndrome; Drug Resistance, Neoplasm; Erythroid Precursor Cells; Erythropoiesis; GATA1 Transcription Factor; Gene Dosage; Gene Expression Regulation, Leukemic; Genetic Predisposition to Disease; Humans; K562 Cells; Leukemia, Megakaryoblastic, Acute; Leukemia, Myeloid; Megakaryocytes; Neoplasm Proteins; Proto-Oncogene Mas; Proto-Oncogene Protein c-ets-2; Thrombopoiesis	2008
X-ray-induced chromosome aberrations in Down lymphocytes: an explanation of their increased sensitivity. Environmental mutagenesis, 1981, Volume: 3, Issue:1 Topics: Chromosome Aberrations; Cytarabine; Down Syndrome; Humans; Lymphocytes; Radiation, Ionizing; X-Rays	1981
G2 phase repair of X-ray-induced chromosomal DNA damage in trichothiodystrophy cells. Mutation research, 1995, Volume: 346, Issue:2 Topics: Abnormalities, Multiple; Ataxia Telangiectasia; Cell Line; Chromosome Aberrations; Chromosomes, Human; Cockayne Syndrome; Cytarabine; DNA Damage; DNA Repair; Down Syndrome; G2 Phase; Hair; Humans; Skin; Skin Diseases; X-Rays; Xeroderma Pigmentosum	1995
X-ray-induced chromatid damage in cells from Down syndrome and Alzheimer disease patients in relation to DNA repair and cancer proneness. Cancer genetics and cytogenetics, 1993, Oct-01, Volume: 70, Issue:1 Topics: Adult; Aged; Alzheimer Disease; Cell Cycle; Chromatids; Cytarabine; DNA Damage; DNA Repair; Down Syndrome; Female; Humans; In Vitro Techniques; Interphase; Male; Middle Aged; Neoplasms; X-Rays	1993
Leukemic blasts with markers of four cell lineages in Down's syndrome ("megakaryoblastic leukemia"). Medical and pediatric oncology, 1993, Volume: 21, Issue:4 Topics: Adolescent; Adult; Antibodies, Monoclonal; Antigens, CD; Biomarkers, Tumor; Cytarabine; Down Syndrome; Doxorubicin; Female; Humans; Immunophenotyping; Leukemia, Megakaryoblastic, Acute; Male; Microscopy, Fluorescence; Neoplastic Stem Cells	1993
Erythroblastic and/or megakaryoblastic leukemia in Down syndrome: treatment with low-dose arabinosyl cytosine. Journal of pediatric hematology/oncology, 1996, Volume: 18, Issue:1 Topics: Antimetabolites, Antineoplastic; Child, Preschool; Cytarabine; Disease-Free Survival; Down Syndrome; Drug Administration Schedule; Female; Humans; Infant; Leukemia, Erythroblastic, Acute; Leukemia, Megakaryoblastic, Acute; Male; Remission Induction	1996
Trisomy 21 in acute myeloid leukemia. Cancer genetics and cytogenetics, 1996, Volume: 86, Issue:2 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Down Syndrome; Humans; Hydroxyurea; Idarubicin; Karyotyping; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myelomonocytic, Acute; Male; Mitoxantrone	1996
Enhanced metabolism of 1-beta-D-arabinofuranosylcytosine in Down syndrome cells: a contributing factor to the superior event free survival of Down syndrome children with acute myeloid leukemia. Blood, 1996, Apr-15, Volume: 87, Issue:8 Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Cell Line, Transformed; Cells, Cultured; Child; Child, Preschool; Chromosomes, Human, Pair 21; Cystathionine beta-Synthase; Cytarabine; Deoxycytosine Nucleotides; Disease-Free Survival; Down Syndrome; Female; Herpesvirus 4, Human; Homocysteine; Humans; Infant; Infant, Newborn; Leukemia, Megakaryoblastic, Acute; Leukemia, Myeloid; Male; Methotrexate; Myelodysplastic Syndromes; Neoplastic Stem Cells; Remission, Spontaneous; Survival Rate	1996
High-dose cytosine arabinoside and fractionated total body irradiation as a preparative regimen for the treatment of children with acute lymphoblastic leukemia and Down syndrome by allogeneic bone marrow transplantation. Bone marrow transplantation, 1996, Volume: 17, Issue:2 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child, Preschool; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Daunorubicin; Down Syndrome; Fatal Outcome; Graft vs Host Disease; Humans; Male; Mercaptopurine; Methotrexate; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Salvage Therapy; Transplantation, Homologous; Vincristine; Whole-Body Irradiation	1996
Fluorescent light-induced chromatid breaks distinguish Alzheimer disease cells from normal cells in tissue culture. Proceedings of the National Academy of Sciences of the United States of America, 1996, May-14, Volume: 93, Issue:10 Topics: Alzheimer Disease; Caffeine; Case-Control Studies; Cells, Cultured; Chromatids; Cytarabine; DNA; DNA Damage; DNA Repair; Down Syndrome; Female; Fibroblasts; G1 Phase; G2 Phase; Humans; Light; Lymphocytes; Male; Ultraviolet Rays	1996
Myeloblasts from Down syndrome children with acute myeloid leukemia have increased in vitro sensitivity to cytosine arabinoside and daunorubicin. Leukemia, 1997, Volume: 11, Issue:9 Topics: Acute Disease; Bone Marrow; Cell Survival; Child; Cytarabine; Daunorubicin; Down Syndrome; Humans; Leukemia, Myeloid; Tumor Cells, Cultured	1997
Acute myelogenous leukemia in Down's syndrome: report of a single pediatric institution using a BFM treatment strategy. Leukemia research, 1998, Volume: 22, Issue:5 Topics: Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Argentina; Bone Marrow Cells; Child, Preschool; Cytarabine; Down Syndrome; Etoposide; Female; Humans; Idarubicin; Infant; Karyotyping; Leukemia, Myeloid, Acute; Male; Retrospective Studies; Treatment Outcome	1998
Effect of DNA repair inhibitors on the in vitro test for Alzheimer's disease. Journal of the American Geriatrics Society, 1998, Volume: 46, Issue:10 Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Antimetabolites, Antineoplastic; Cells, Cultured; Chromatids; Chromosome Breakage; Cytarabine; DNA Damage; DNA Repair; Down Syndrome; Female; Humans; Light; Male; Middle Aged	1998
Trisomy 21 associated transient neonatal myeloproliferation in the absence of Down's syndrome. Archives of disease in childhood. Fetal and neonatal edition, 1998, Volume: 79, Issue:3 Topics: Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 6; Cytarabine; Down Syndrome; Etoposide; Female; Hematopoietic Stem Cells; Humans; In Situ Hybridization, Fluorescence; Infant, Newborn; Karyotyping; Male; Mitoxantrone; Myeloproliferative Disorders; Time Factors	1998
Transient myeloproliferative disorder associated with trisomy 21: is a short course of chemotherapy indicated in patients with liver impairment and severe clinical problems? Medical and pediatric oncology, 1999, Volume: 32, Issue:6 Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Down Syndrome; Drug Administration Schedule; Dyspnea; Fever; Hepatomegaly; Humans; Infant, Newborn; Male; Muscle Weakness; Myeloproliferative Disorders; Nutrition Disorders; Splenomegaly	1999
Expression of chromosome 21-localized genes in acute myeloid leukemia: differences between Down syndrome and non-Down syndrome blast cells and relationship to in vitro sensitivity to cytosine arabinoside and daunorubicin. Blood, 1999, Aug-15, Volume: 94, Issue:4 Topics: Adolescent; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Child; Child, Preschool; Chromosomes, Human, Pair 21; Cytarabine; Daunorubicin; Down Syndrome; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Infant; Infant, Newborn; Leukemia, Myeloid; Leukocytes; Tumor Cells, Cultured	1999
Cellular cytotoxic drug sensitivity in children with acute leukemia and Down's syndrome: an explanation to differences in clinical outcome? Leukemia, 2000, Volume: 14, Issue:5 Topics: Antineoplastic Agents; Blast Crisis; Cell Survival; Child; Cytarabine; Dexamethasone; Down Syndrome; Doxorubicin; Etoposide; Humans; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Thioguanine; Treatment Outcome; Tumor Cells, Cultured	2000
Cystathionine-beta-synthase cDNA transfection alters the sensitivity and metabolism of 1-beta-D-arabinofuranosylcytosine in CCRF-CEM leukemia cells in vitro and in vivo: a model of leukemia in Down syndrome. Cancer research, 2000, Nov-15, Volume: 60, Issue:22 Topics: Animals; Antimetabolites, Antineoplastic; Chromosomes, Human, Pair 21; Cystathionine beta-Synthase; Cytarabine; Deoxycytidine Kinase; DNA, Complementary; Down Syndrome; Female; Gene Expression; Humans; Leukemia, Experimental; Male; Mice; Mice, Inbred ICR; Mice, SCID; Transfection; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2000
Different drug sensitivity profiles of acute myeloid and lymphoblastic leukemia and normal peripheral blood mononuclear cells in children with and without Down syndrome. Blood, 2002, Jan-01, Volume: 99, Issue:1 Topics: Amsacrine; Anthracyclines; Antineoplastic Agents; Busulfan; Cell Survival; Child; Child, Preschool; Cytarabine; Down Syndrome; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Etoposide; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Thioguanine; Vincristine	2002
Acute myeloid leukemia (AML) in Down's syndrome is highly responsive to chemotherapy: experience on Pediatric Oncology Group AML Study 8498. Blood, 1992, Nov-01, Volume: 80, Issue:9 Topics: Acute Disease; Adolescent; Adult; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Azacitidine; Child; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Daunorubicin; Down Syndrome; Etoposide; Female; Follow-Up Studies; Humans; Leukemia, Myeloid; Male; Mercaptopurine; Methotrexate; Prednisone; Remission Induction; Thioguanine; Vincristine	1992
[Cure of acute myeloblastic leukemia in a child with Down syndrome and tetralogy of Fallot]. Wiadomosci lekarskie (Warsaw, Poland : 1960), 1992, Volume: 45, Issue:5-6 Topics: Abnormalities, Multiple; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Down Syndrome; Humans; Infant; Leukemia, Myeloid, Acute; Male; Remission Induction; Tetralogy of Fallot; Thioguanine	1992
Efficacy of low-dose Aracytine in 3 cases of refractory anemia in transformation in children. Nouvelle revue francaise d'hematologie, 1988, Volume: 30, Issue:4 Topics: Anemia, Refractory; Child, Preschool; Cytarabine; Down Syndrome; Female; Humans; Male; Remission Induction	1988
[Megakaryoblastic leukemia with hypodiploidy in a girl with trisomy 21]. Annales de pediatrie, 1985, Volume: 32, Issue:6 Topics: Blood Platelets; Bone Marrow; Child, Preschool; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Down Syndrome; Female; Humans; Leukemia; Primary Myelofibrosis	1985
Studies of cellular proliferation in human leukemia. 3. Behavior of leukemic cells in three adults with acute leukemia given continuous infusions of 3H-thymidine for 8 or 10 days. Cancer, 1970, Volume: 25, Issue:6 Topics: Acute Disease; Adult; Aged; Autoradiography; Bone Marrow; Bone Marrow Cells; Cell Division; Cell Nucleus; Culture Techniques; Cytarabine; Down Syndrome; Female; Floxuridine; Humans; Karyotyping; Leukemia; Leukocytes; Lymphocytes; Male; Mitosis; Prednisone; Thioguanine; Thymidine; Tritium; Vincristine	1970