cytarabine has been researched along with Disease Models, Animal in 119 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 45 (37.82) | 18.7374 |
| 1990's | 11 (9.24) | 18.2507 |
| 2000's | 15 (12.61) | 29.6817 |
| 2010's | 42 (35.29) | 24.3611 |
| 2020's | 6 (5.04) | 2.80 |
| Authors | Studies |
|---|---|
| Freeze, HH | 1 |
| Chen, G; Peng, L; Peng, S; Wang, Y; Wu, J; Yang, Y; Zhang, X; Zhao, M; Zheng, M | 1 |
| Braisted, J; Dranchak, P; Earnest, TW; Gu, X; Hoon, MA; Inglese, J; Oliphant, E; Solinski, HJ | 1 |
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Ben Khoud, M; Brinster, C; Figeac, M; Leprêtre, F; Mopin, A; Quesnel, B; Sebda, S; Villenet, C | 1 |
| Baggett, MA; Guillory, C; Jones, M; Steele, C; Sullivan, BN | 1 |
| Chu, W; Dong, JJ; Jin, XJ; Li, GQ; Li, JJ; Li, YL; Liu, YQ; Yao, J | 1 |
| Khodadoost, A; Kiani, A; Nik, SH; Pourahmad, J; Salimi, A | 1 |
| Cao, Z; Dong, H; Guan, D; Hou, J; Li, G; Yang, W; Zhao, X | 1 |
| Cole, PD; Gulinello, ME; Schmiegelow, K; Thomsen, AM; Wen, J | 1 |
| He, W; Hu, X; Jiang, W; Li, Z; Liu, R; Luan, Y; Zhang, D; Zhang, J | 1 |
| Gangoso, E; Marques-Torrejon, MA; Pollard, SM | 1 |
| Gao, Y; Min, Q; Sun, W; Wang, J; Zheng, M | 1 |
| Hu, L; Liu, M; Pan, S; Pei, L; Shang, Y; Song, L; Wu, Y; Xian, W; Xiong, W; Yao, S | 1 |
| Chen, BY; Cheng, D; Clark, PM; Salas, JR; Van Arnam, JS; Witte, ON; Wong, A | 1 |
| Chen, YL; Duan, CW; Fu, W; Hong, DL; Li, H; Li, MH; Liang, AB; Liu, SL; Sun, HY; Tang, C; Tang, ZH; Zhang, MY; Zhang, WJ; Zheng, WW; Zhou, BS | 1 |
| Han, AR; Hwang, HS; Kim, HJ; Lee, JY; Min, WS; Park, GS | 1 |
| Azam, M; Bu, J; Ding, W; Hu, C; Huang, G; Jin, J; Kesarwani, M; Lin, P; Luo, Y; Ma, L; Mei, C; Ren, Y; Tang, Y; Tong, H; Xu, W; Yan, X; Ye, L; Zhan, D; Zhang, H; Zhou, X; Zhou, Y; Zhu, S | 1 |
| Kontoyiannis, DP; Zanette, RA | 1 |
| Andersson, A; Dannaeus, K; Delfani, K; Di Monte, DA; Haegerstrand, A; Häggblad, J; Hill, MP; Isacson, R; Janson Lang, AM; McCormack, AL; Nielsen, E; Palmer, T; Patrone, C; Rönnholm, H; Wikstrom, L; Zachrisson, O; Zhao, M | 1 |
| Moradi, PW; Petraitiene, R; Petraitis, V; Strauss, GE; Such, KA; Walsh, TJ | 1 |
| Chwee, JY; Gasser, S; Huang, CW; Le Bert, N; Lee, SK; Ma, CA | 1 |
| Baik, H; Bossis, G; Boutzen, H; Brockly, F; Kaoma, T; Kifagi, C; Manenti, S; Pelegrin, M; Piechaczyk, M; Récher, C; Ristic, M; Saland, E; Salem, T; Sarry, JE; Vallar, L; Vergez, F | 1 |
| Cai, YJ; Chen, GQ; Chen, J; Duan, CW; Enver, T; Hong, DL; Li, LH; Li, ZQ; Mi, JQ; Qin, X; Shi, J; Tao, Y; Wang, B; Yin, MZ; Yu, YH; Zhang, F; Zhou, XC | 1 |
| Al-Malki, H; Cebrian-Silla, A; Fehse, B; Fransen, NL; Garcia-Verdugo, JM; Gomez-Nicola, D; Perry, VH; Riecken, K; Suzzi, S; Vargas-Caballero, M | 1 |
| He, C; Mao, ZJ; Singleton, TP; Su, G; Tan, D; Wei, L; Yin, B; Zhao, W; Zheng, Y | 1 |
| Bai, CX; Wang, HY; Wang, QC; Zhu, XH | 1 |
| Ikezoe, T; Nishioka, C; Yokoyama, A | 1 |
| Bruheim, S; Suo, Z; Wendel, T; Wiedlocha, A; Zhen, Y | 1 |
| Cheng, H; Gao, L; Hu, X; Liu, N; Tang, G; Wang, C; Wang, J; Wang, L | 1 |
| Acer, S; Balci, YI; Bozkurt, K; Kucukatay, V; Polat, A; Sarbay, H; Yagci, R | 1 |
| Fukushima, N; Hayakawa, F; Jamieson, C; Kakiuchi, S; Kiyoi, H; Kuwatsuka, Y; Minami, Y; Naoe, T | 1 |
| Alam, M; Klanova, M; Klener, P; Lateckova, L; Molinsky, J; Soukup, T; Trneny, M; Vockova, P; Zivny, J | 1 |
| An, X; Cai, J; Huang, L; Li, QX; Liu, J; Wang, D; Wang, N; Wery, JP; Zhang, L; Zhou, D; Zhou, J | 1 |
| Baldauf, HM; Berdel, WE; Bohnenberger, H; Cinatl, J; Comoglio, F; Cremer, A; Ferreirós, N; Flick, R; Geisslinger, G; Hansmann, ML; Hartmann, W; Hornung, V; Kaderali, L; Keppler, OT; Lohmeyer, J; Martin, M; Michaelis, M; Oellerich, T; Schliemann, C; Schneider, C; Schwarz, SM; Serve, H; Stegmann, L; Ströbel, P; Thomas, D; Wardelmann, E; Yakunin, AF | 1 |
| Axelsson, H; Bladh, J; Bulli, L; Calderón-Montaño, JM; Grandér, D; Hagenkort, A; Helleday, T; Henter, JI; Herold, N; Heshmati, Y; Heyman, M; Höglund, A; Jemth, AS; Kogner, P; Kutzner, J; Lehmann, S; Ljungblad, L; Loseva, O; Lundbäck, T; Myrberg, IH; Page, BD; Paulin, CB; Rassidakis, G; Rudd, SG; Sanjiv, K; Schaller, T; Sundin, M; Tamm, KP; Tesi, B; Uhlin, M; Valerie, NC; Walfridsson, J; Warpman-Berglund, U; Wiita, E | 1 |
| Ashton, S; Barry, ST; Caddy, J; Curtis, NJ; Derbyshire, N; Floc'h, N; Harris, E; Hattersley, M; Jacobs, VN; Maratea, K; Odedra, R; Pease, EJ; Pilling, JE; Taylor, P; Trueman, D; Wen, S | 1 |
| Honda, M; Nakano, T; Ono, H; Tanabe, M | 1 |
| Arbitrario, JP; Fox, JA; Hawtin, RE; Howlett, AR; Kumer, JL; Scatena, CD; Silverman, JA | 1 |
| Duan, WM; Gonzalez-Toledo, ME; Guo, WP; Li, B; Liu, XY; Piao, CS; Xue, YQ; Zhao, LR | 1 |
| Cho, SR; Im, SH; Kim, GW; Kim, HO; Lee, JE; Park, CI; Park, ES; Park, KI; Yu, JH | 1 |
| Lowe, SW; Pardee, TS; Zuber, J | 1 |
| Baker, SD; Calabrese, C; Campana, D; Fan, Y; Hu, S; Inaba, H; Niu, H; Orwick, S; Panetta, JC; Pounds, S; Rehg, JE; Rose, C; Rubnitz, JE; Yang, S | 1 |
| Andreeff, M; Hashimoto, N; Honda, H; Ishizawa, J; Kai, K; Kanno, M; Kojima, K; Miwa, M; Nagata, K; Okada, S; Onishi, N; Saya, H; Shimizu, T; Sugihara, E | 1 |
| Burguete, Y; Ferguson, RJ; Fessler, CL; Fremouw, T | 1 |
| Barta, SK; Bhagat, TD; Schindler, J; Shenoy, N; Steidl, U; Verma, A; Zou, Y | 1 |
| Audet, JN; Gowing, G; Julien, JP; Paradis, R; Soucy, G | 1 |
| Brown, PL; Cadet, JL; Elmer, GI; Greenwald, M; Krasnova, IN; Mayo, CL; McFarland, R; Schoonover, C; Shepard, PD; Stockman, S; Vogel, MW | 1 |
| Pardee, TS | 1 |
| Chang, RC; Lau, BW; Lee, TM; Ma, H; So, KF; Yau, SY; Zhang, E | 1 |
| He, Q; Jiang, DZ; Na, XD | 1 |
| Fu, L; Guo, X; Jia, K; Lu, W; Song, J; Yang, Y; Yu, M | 1 |
| Elmer, GI; Guard, H; Hercher, E; Sydnor, J; Vogel, MW | 1 |
| Chopp, M; Gousev, A; Ho, KL; Morshead, C; Wang, L; Wang, Y; Zhang, L; Zhang, R; Zhang, Z | 1 |
| Chu, K; Jeong, SW; Jung, KH; Kim, JY; Kim, M; Lee, SK; Lee, ST; Roh, JK; Song, YM | 1 |
| Feuring-Buske, M; Frankel, AE; Gerhard, B; Hogge, DE | 1 |
| Bauman, J; Biroc, SL; Chesney, SK; Dinter, H; Ho, E; Hoffmann, J; Kirkland, T; Liu, HL; Shen, J; Subramanyam, B; Tseng, JL; Zajchowski, DA | 1 |
| Nakagawa, T | 1 |
| Gardner, J; Gonen, M; Heaney, M; O'Connor, OA; Sirotnak, F; Smith, EA; Teruya-Feldstein, J; Toner, LE; Vrhovac, R | 1 |
| Akahori, S; Ohno, M; Takano, T; Takeuchi, Y | 1 |
| Aguila, B; Allouche, S; Balboni, G; Borsodi, A; Boulouard, M; Coulbault, L; Davis, A; Jauzac, P; Léveillé, F; Salvadori, S; Tóth, G | 1 |
| Jooss, K; Li, B; Lin, JM; Rimmer, E; VanRoey, M | 1 |
| Narang, HK | 1 |
| Ando, K; Mano, Y; Matsui, K; Mukoyama, M; Muramoto, O; Toyoshima, E | 1 |
| Eichler, G; Habs, M; Schmähl, D | 1 |
| Colly, LP; Hagenbeek, A; van Bekkum, DW | 1 |
| Ohi, K; Tsuji, M; Yamada, N | 1 |
| Hussein, AM | 1 |
| Hussein, AM; Peters, WP; Stuart, A | 1 |
| Goto, M; Goto, MP; Hurley, RM; Picken, M; Zeller, WP | 1 |
| Alvarez-Leite, J; Bambirra, EA; Cara, DC; Nicoli, JR; Ramos, MG; Vieira, EC | 1 |
| Balzarini, J; Breistøl, K; De Clercq, E; Fodstad, O; Martinsen, M; Myhren, F; Sandvold, ML | 1 |
| El-Beltagi, HM; Hagenbeek, A; Martens, AC | 1 |
| Cattaneo-Pangrazzi, RM; Eriksson, S; Fichtner, I; Horber, DH; Ludwig, PS; Schott, H; Schwendener, RA; von Ballmoos, P | 1 |
| Benedict, WF; Khwaja, TA | 1 |
| Bocaccino, CA; Greenberger, JS; Moloney, WC; Szot, SJ | 1 |
| Marks, MI | 1 |
| Hatch, LA; Percy, DH | 1 |
| Butler, SR; Casagrande, S; Fitzwilliam, JF; Griffith, JF | 1 |
| Glasgow, LA; Kelsey, DK; Kern, ER; Overall, JC | 1 |
| De Clercq, E; Luczak, M | 1 |
| Boyd, MR; Harris, SR | 1 |
| Conliffe, M; Worthington, M | 1 |
| Bauer, DJ; Collins, P | 1 |
| Chemik, NL; Posner, JB; Shapiro, WR; Ushio, Y; Young, DF | 1 |
| Codd, AA; Narang, HK | 1 |
| Kaufman, HE | 1 |
| Danylchuk, KD; Percy, DH | 1 |
| Bergsagel, DE; Librach, SL; Ogawa, M | 1 |
| Keogh, B; Murphy, GP; Williams, P | 1 |
| Huang, HS; Jimenez, JJ | 1 |
| Pizzo, PA; Walsh, TJ | 1 |
| Assil, KK; Blumenkranz, M; Hartzer, M; Nehorayan, M; Ward, T; Weinreb, RN | 1 |
| Jimenez, JJ; Wong, GH; Yunis, AA | 1 |
| Hussein, AM; Jimenez, JJ; McCall, CA; Yunis, AA | 1 |
| Hunt, A; Patel, AJ; Seaton, P | 1 |
| Bacher, J; Pizzo, PA; Walsh, TJ | 1 |
| Colly, LP; Edelbroek, PM; Honders, W; vd Hoorn, F; Willemze, R | 1 |
| Glynn, JP; Goldberg, AI; Goldin, A; Kende, M; Mantel, N | 1 |
| Mott, MG | 1 |
| Kline, I | 1 |
| Ablashi, DV; Adamson, RH; Cicmanec, JL; Dalgard, DW | 1 |
| Koprowski, H | 1 |
| Hahn, E; Maruyama, Y; Schwartz, S; Thomson, JM | 1 |
| Schabel, FM; Skipper, HE | 1 |
| Baringer, JR; Panitch, HS | 1 |
| Cheeks, JB; Laster, WR; Schabel, FM; Skipper, HE; Trader, MW | 1 |
| Amiel, JL; De Vassal, F; Hayat, M; Jasmin, C; Mathé, G; Pouillart, P; Rappaport, H; Rosenfeld, C; Schneider, M; Schwarzenberg, L; Weiner, R | 1 |
| Handschumacher, RE; Summers, WP | 1 |
| Frei, E; Goldin, A; Schabel, FM | 1 |
| Arima, E; Byfield, JE; Finklestein, JZ; Fonkalsrud, EW | 1 |
| Frei, E; Goldin, A; Henderson, ES; Holland, JF; Newman, JW; Sandberg, JS | 1 |
| Ellison, ED; Kaufman, HE; Townsend, WM | 1 |
| Shapiro, WR | 1 |
| Zubrod, CG | 1 |
| Holland, JF | 1 |
| Gordon, RO; Mitchell, MS; Wade, ME | 1 |
| Shackney, SE | 1 |
| Brockman, RW; Lloyd, HH; Mellett, LB; Montgomery, JA; Schabel, FM; Skipper, HE; Wilkoff, LJ | 1 |
2 review(s) available for cytarabine and Disease Models, Animal
| Article | Year |
|---|---|
Sweet solution: sugars to the rescue.
Topics: Animals; Carrier Proteins; Colitis; Dietary Supplements; Disease Models, Animal; Fucose; Glucosamine; Guanosine Diphosphate Fucose; Humans; Leukocyte-Adhesion Deficiency Syndrome; Mice; Mice, Knockout; Monosaccharide Transport Proteins; Mutation; Osteoarthritis | 2002 |
The chemotherapy of human and animal acute leukemia.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Asparaginase; Azaserine; Cell Division; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Disease Models, Animal; Drug Combinations; Humans; Kinetics; Leukemia L1210; Leukemia, Experimental; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Neoplasms; Prednisone; Remission, Spontaneous; RNA, Neoplasm; Vincristine | 1971 |
1 trial(s) available for cytarabine and Disease Models, Animal
| Article | Year |
|---|---|
The chemotherapy of human and animal acute leukemia.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Asparaginase; Azaserine; Cell Division; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Disease Models, Animal; Drug Combinations; Humans; Kinetics; Leukemia L1210; Leukemia, Experimental; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Neoplasms; Prednisone; Remission, Spontaneous; RNA, Neoplasm; Vincristine | 1971 |
117 other study(ies) available for cytarabine and Disease Models, Animal
| Article | Year |
|---|---|
A class of novel N-isoquinoline-3-carbonyl-L-amino acid benzylesters: synthesis, anti-tumor evaluation and 3D QSAR analysis.
Topics: Animals; Antineoplastic Agents; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Esters; HeLa Cells; HL-60 Cells; Humans; Isoquinolines; Mice; Molecular Structure; Quantitative Structure-Activity Relationship; Stereoisomerism | 2011 |
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, Spinal; Humans; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pruritus; Receptors, Atrial Natriuretic Factor; Reproducibility of Results; Signal Transduction; Small Molecule Libraries | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Detection of residual and chemoresistant leukemic cells in an immune-competent mouse model of acute myeloid leukemia: Potential for unravelling their interactions with immunity.
Topics: Animals; Cytarabine; Disease Models, Animal; Disease Progression; Humans; Leukemia, Myeloid, Acute; Mice; Neoplasm, Residual | 2022 |
Neuroimmune Responses in a New Experimental Animal Model of Cerebral Aspergillosis.
Topics: Adrenal Cortex Hormones; Animals; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Chemokines; Chemokines, CXC; Cytarabine; Daunorubicin; Disease Models, Animal; Humans; Interleukin-17; Interleukin-6; Invasive Pulmonary Aspergillosis; Ligands; Lung; Mice; Pneumonia; Steroids; Vascular Endothelial Growth Factor A | 2022 |
[Animal Model Establishment and Its Mechanism of Cytarabine-Iduced Myelosuppression].
Topics: Animals; Bone Marrow Cells; Bone Marrow Diseases; Cytarabine; Disease Models, Animal; Mice; Mice, Inbred C57BL | 2022 |
Trifluoperazine an Antipsychotic Drug and Inhibitor of Mitochondrial Permeability Transition Protects Cytarabine and Ifosfamide-Induced Neurotoxicity.
Topics: Animals; Antineoplastic Agents; Brain; Cells, Cultured; Cytarabine; Disease Models, Animal; Humans; Ifosfamide; Lipid Peroxidation; Membrane Potential, Mitochondrial; Mitochondria; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Oxidative Stress; Primary Cell Culture; Rats; Rats, Wistar; Reactive Oxygen Species; Trifluoperazine | 2020 |
Expression of Fibroblast Growth Factor 4 in a Rat Model of Polydactyly of the Thumb Induced by Cytarabine.
Topics: Animals; Cytarabine; Disease Models, Animal; Embryo, Mammalian; Female; Fibroblast Growth Factor 4; Humans; Male; Polydactyly; Rats; Rats, Sprague-Dawley; Thumb | 2020 |
Liposomal Cytarabine Induces Less Neurocognitive Dysfunction Than Intrathecal Methotrexate in an Animal Model.
Topics: Animals; Antimetabolites, Antineoplastic; Cognition; Cytarabine; Delayed-Action Preparations; Disease Models, Animal; Female; Hematopoiesis; Liposomes; Male; Rats; Rats, Long-Evans | 2018 |
Rational Design of a New Self-Codelivery System from Redox-Sensitive Camptothecin-Cytarabine Conjugate Assembly for Effectively Synergistic Anticancer Therapy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Cell Line, Tumor; Cytarabine; Disease Models, Animal; Drug Delivery Systems; Drug Liberation; Drug Synergism; Female; Glutathione; HT29 Cells; Human Umbilical Vein Endothelial Cells; Humans; Magnetic Resonance Imaging; Mice; Nanoparticles | 2017 |
Modelling glioblastoma tumour-host cell interactions using adult brain organotypic slice co-culture.
Topics: Aging; Animals; Antigens, CD; Biomarkers, Tumor; Brain; Brain Neoplasms; Cell Communication; Cell Proliferation; Coculture Techniques; Culture Media, Serum-Free; Cytarabine; Dacarbazine; Disease Models, Animal; Endothelial Cells; Glioblastoma; Humans; Mice, Inbred C57BL; Neoplastic Stem Cells; Neural Stem Cells; Organ Specificity; Stem Cell Niche; Temozolomide; Tumor Microenvironment; Xenograft Model Antitumor Assays | 2018 |
The dual regulatory function of lienal peptide on immune system.
Topics: Animals; Arthritis, Experimental; Cattle; Cytarabine; Cytokines; Dinitrofluorobenzene; Disease Models, Animal; Gene Expression Regulation; Immunomodulation; Immunosuppression Therapy; Inflammation Mediators; Lipopolysaccharides; Lymphocyte Activation; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Peptides; Rats; Rats, Wistar; Signal Transduction; Spleen | 2018 |
DAPK1-ERK signal mediates oxygen glucose deprivation reperfusion induced apoptosis in mouse N2a cells.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cerebral Cortex; Cytarabine; Death-Associated Protein Kinases; Disease Models, Animal; Excitatory Amino Acid Agonists; Glucose; Glycine; Hypoxia; Immunosuppressive Agents; Infarction, Middle Cerebral Artery; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neuroblastoma; Neurons; Protein Biosynthesis; RNA, Small Interfering | 2018 |
Topics: Animals; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cytarabine; Disease Models, Animal; Hepatitis, Autoimmune; Liver; Male; Mice; Mice, Inbred BALB C; Positron Emission Tomography Computed Tomography | 2018 |
Chemotherapy-induced niche perturbs hematopoietic reconstitution in B-cell acute lymphoblastic leukemia.
Topics: Animals; Apoptosis; Bone Marrow Cells; Cell Differentiation; Cell Self Renewal; Cytarabine; Disease Models, Animal; Flow Cytometry; Gene Expression Regulation, Leukemic; Hematopoietic Stem Cells; Humans; Mesenchymal Stem Cells; Mice; N-Myc Proto-Oncogene Protein; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Reactive Oxygen Species; Stem Cell Niche | 2018 |
Enhanced Anti-Leukemic Effects through Induction of Immunomodulating Microenvironment by Blocking CXCR4 and PD-L1 in an AML Mouse Model.
Topics: Animals; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; B7-H1 Antigen; Benzylamines; Cell Line, Tumor; Cyclams; Cytarabine; Disease Models, Animal; Heterocyclic Compounds; Humans; Immunomodulation; Immunotherapy; Leukemia, Myeloid, Acute; Mice; Mice, Inbred C57BL; Myeloid Progenitor Cells; Receptors, CXCR4; Tumor Microenvironment | 2019 |
The high NRF2 expression confers chemotherapy resistance partly through up-regulated DUSP1 in myelodysplastic syndromes.
Topics: Animals; Antimetabolites, Antineoplastic; Base Sequence; Binding Sites; Cells, Cultured; Cytarabine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Dual Specificity Phosphatase 1; Gene Expression Regulation; Gene Knockout Techniques; Genetic Loci; Humans; Immunohistochemistry; Mice; Mice, Knockout; Models, Biological; Myelodysplastic Syndromes; NF-E2-Related Factor 2; Protein Binding | 2019 |
Pre-exposure of Candida species to cytarabine and daunorubicin does not affect their in vitro antifungal susceptibility and virulence in flies.
Topics: Animals; Antifungal Agents; Biological Assay; Candida; Cytarabine; Daunorubicin; Diptera; Disease Models, Animal; Survival Analysis; Virulence | 2013 |
Restorative effects of platelet derived growth factor-BB in rodent models of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Angiogenesis Inducing Agents; Animals; Becaplermin; Cell Proliferation; Cytarabine; Disease Models, Animal; Drug Administration Schedule; Immunosuppressive Agents; Male; Mice; Mice, Inbred C57BL; Motor Activity; Neurotoxins; Oxidopamine; Parkinson Disease; Proto-Oncogene Proteins c-sis; Rats; Rats, Sprague-Dawley; Time Factors | 2011 |
Environmental monitoring for Aspergillus fumigatus in association with an immunosuppressed rabbit model of pulmonary aspergillosis.
Topics: Animals; Aspergillosis; Aspergillus fumigatus; Cytarabine; Disease Models, Animal; Environmental Monitoring; Female; Housing, Animal; Humans; Immunosuppressive Agents; Lung; Methylprednisolone; Neutropenia; Pulmonary Aspergillosis; Rabbits | 2013 |
Synergistic anticancer effects of Pam3CSK4 and Ara-C on B-cell lymphoma cells.
Topics: Animals; Antimetabolites, Antineoplastic; Bone Marrow Cells; Cell Line, Tumor; Cell Transformation, Neoplastic; Cluster Analysis; Cytarabine; Disease Models, Animal; Drug Synergism; Enzyme Activation; Gene Expression Profiling; Immunomodulation; Killer Cells, Natural; Lipopeptides; Lymphoid Progenitor Cells; Lymphoma, B-Cell; Mice; Mice, Transgenic; NF-kappa B; T-Lymphocytes; Toll-Like Receptor 2 | 2014 |
The ROS/SUMO axis contributes to the response of acute myeloid leukemia cells to chemotherapeutic drugs.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cytarabine; Daunorubicin; Disease Models, Animal; Etoposide; Female; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Male; Mice; Mice, Nude; Microarray Analysis; Reactive Oxygen Species; SUMO-1 Protein; U937 Cells; Xenograft Model Antitumor Assays | 2014 |
Leukemia propagating cells rebuild an evolving niche in response to therapy.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bone Marrow Cells; Cytarabine; Daunorubicin; Disease Models, Animal; Humans; Mice; Mice, Inbred NOD; Mice, SCID; Neoplastic Stem Cells; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stem Cell Niche; Tumor Microenvironment; Xenograft Model Antitumor Assays | 2014 |
Temporal dynamics of hippocampal neurogenesis in chronic neurodegeneration.
Topics: Adult; Aged; Alzheimer Disease; Animals; Antimetabolites, Antineoplastic; Cell Proliferation; Chronic Disease; Creutzfeldt-Jakob Syndrome; Cytarabine; Dentate Gyrus; Disease Models, Animal; Disease Progression; Female; Genetic Vectors; Hippocampus; Humans; Male; Mice; Mice, Inbred C57BL; Middle Aged; Mossy Fibers, Hippocampal; Neural Pathways; Neural Stem Cells; Neuroanatomical Tract-Tracing Techniques; Neurodegenerative Diseases; Neurogenesis; Patch-Clamp Techniques; Prion Diseases; Prions; Time Factors; Tissue Banks; Young Adult | 2014 |
Cellular intrinsic mechanism affecting the outcome of AML treated with Ara-C in a syngeneic mouse model.
Topics: Animals; Antimetabolites, Antineoplastic; Biphenyl Compounds; Cell Line, Tumor; Cytarabine; Disease Models, Animal; Down-Regulation; Drug Resistance, Neoplasm; Gene Expression Profiling; Inhibitor of Apoptosis Proteins; Leukemia, Myeloid, Acute; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Nitrophenols; Piperazines; Sulfonamides; Survival Rate; Transplantation, Homologous; Up-Regulation | 2014 |
[Effect of Bear Bile Powder and Its Succedaneum on Peripheral Blood and Bone Marrow Megakaryocytes in Mouse Model with Thrombocytopenia Induced by Cytosine Arabinoside].
Topics: Animals; Bile; Bone Marrow; Bone Marrow Cells; Cytarabine; Disease Models, Animal; Megakaryocytes; Mice; Spleen; Thrombocytopenia | 2015 |
Blockade of CD82 by a monoclonal antibody potentiates anti-leukemia effects of AraC in vivo.
Topics: Animals; Antibodies, Monoclonal; Antigens, CD34; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Cytarabine; Disease Models, Animal; Drug Synergism; Humans; Kangai-1 Protein; Leukemia; Mice; Mice, Transgenic; Xenograft Model Antitumor Assays | 2015 |
The novel HSP90 inhibitor NVP-AUY922 shows synergistic anti-leukemic activity with cytarabine in vivo.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cytarabine; Disease Models, Animal; Female; HSP90 Heat-Shock Proteins; Humans; Isoxazoles; Leukemia; Male; Neoplasm Proteins; Resorcinols; Signal Transduction | 2016 |
Valproic acid enhances the antileukemic effect of cytarabine by triggering cell apoptosis.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; bcl-2-Associated X Protein; Bone Marrow Cells; Cell Line; Cell Proliferation; Cytarabine; Disease Models, Animal; Drug Combinations; Drug Synergism; Enzyme Inhibitors; G1 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; K562 Cells; Leukemia, Myeloid, Acute; Mice; Monocytes; Primary Cell Culture; Signal Transduction; Survival Analysis; Valproic Acid | 2016 |
N-acetylcysteine supplementation reduces oxidative stress for cytosine arabinoside in rat model.
Topics: Acetylcysteine; Animals; Antioxidants; Conjunctiva; Cornea; Cytarabine; Dietary Supplements; Disease Models, Animal; Free Radical Scavengers; Immunosuppressive Agents; Oxidative Stress; Rats; Rats, Wistar | 2017 |
Small-molecule Hedgehog inhibitor attenuates the leukemia-initiation potential of acute myeloid leukemia cells.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Cycle; Cell Line, Tumor; Cell Self Renewal; Cell Transformation, Neoplastic; Cytarabine; Disease Models, Animal; Drug Resistance, Neoplasm; Gene Expression Profiling; Hedgehog Proteins; Humans; Leukemia, Myeloid, Acute; Mice; Neoplastic Stem Cells; Signal Transduction; Xenograft Model Antitumor Assays | 2016 |
Single-agent cytarabine is insufficient for the treatment of human mantle cell lymphoma in mouse xenograft model.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Proliferation; Cisplatin; Cyclophosphamide; Cytarabine; Dexamethasone; Disease Models, Animal; Doxorubicin; Humans; Lymphoma, Mantle-Cell; Mice; Mice, Inbred NOD; Mice, SCID; Prednisone; Treatment Outcome; Vincristine; Xenograft Model Antitumor Assays | 2016 |
AC220 and AraC cause differential inhibitory dynamics in patient-derived M5-AML with FLT3-ITD and, thus, ultimately distinct therapeutic outcomes.
Topics: Aged; Animals; Antimetabolites, Antineoplastic; Benzothiazoles; Cytarabine; Disease Models, Animal; DNA Mutational Analysis; fms-Like Tyrosine Kinase 3; Gene Duplication; Genotype; Humans; Immunophenotyping; Leukemia, Myeloid, Acute; Male; Mice; Mice, Inbred NOD; Mice, SCID; Phenotype; Phenylurea Compounds; Protein Kinase Inhibitors; Tandem Repeat Sequences; Treatment Outcome; Tumor Burden; Xenograft Model Antitumor Assays | 2017 |
SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cytarabine; Daunorubicin; Disease Models, Animal; Female; Flow Cytometry; Humans; Immunoblotting; Leukemia, Myeloid, Acute; Male; Middle Aged; Monomeric GTP-Binding Proteins; Prognosis; Retrospective Studies; SAM Domain and HD Domain-Containing Protein 1; Young Adult | 2017 |
Targeting SAMHD1 with the Vpx protein to improve cytarabine therapy for hematological malignancies.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Arabinofuranosylcytosine Triphosphate; Child; Child, Preschool; Cytarabine; Disease Models, Animal; Female; Humans; In Vitro Techniques; Infant; Leukemia, Myeloid, Acute; Male; Mice; Molecular Targeted Therapy; Monomeric GTP-Binding Proteins; Prognosis; SAM Domain and HD Domain-Containing Protein 1; Viral Regulatory and Accessory Proteins | 2017 |
Optimizing Therapeutic Effect of Aurora B Inhibition in Acute Myeloid Leukemia with AZD2811 Nanoparticles.
Topics: Animals; Antineoplastic Agents; Apoptosis; Aurora Kinase B; Bone Marrow; Cell Line, Tumor; Cytarabine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Mice; Nanoparticles; Organophosphates; Polyploidy; Protein Kinase Inhibitors; Quinazolines; Rats; Tumor Burden; Xenograft Model Antitumor Assays | 2017 |
Glycine transporter blockade ameliorates motor ataxia in a mouse model of spinocerebellar atrophy.
Topics: Animals; Binding Sites; Cytarabine; Disease Models, Animal; Dose-Response Relationship, Drug; Glycine; Glycine Plasma Membrane Transport Proteins; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Receptors, N-Methyl-D-Aspartate; Sarcosine; Serine; Spinocerebellar Ataxias | 2009 |
Voreloxin, a first-in-class anticancer quinolone derivative, acts synergistically with cytarabine in vitro and induces bone marrow aplasia in vivo.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Blood Platelets; Bone Marrow Cells; Cell Proliferation; Cytarabine; Disease Models, Animal; Drug Synergism; Female; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Leukocytes; Mice; Naphthyridines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Thiazoles | 2010 |
Brain self-protection: the role of endogenous neural progenitor cells in adult brain after cerebral cortical ischemia.
Topics: Adult Stem Cells; Analysis of Variance; Animals; Behavior, Animal; Brain Infarction; Brain Ischemia; Bromodeoxyuridine; Cells, Cultured; Cerebral Cortex; Culture Media, Conditioned; Cytarabine; Disease Models, Animal; Green Fluorescent Proteins; Immunosuppressive Agents; In Situ Nick-End Labeling; Lateral Ventricles; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Tissue Proteins; Neurologic Examination; Neurons; SOXB1 Transcription Factors | 2010 |
Induction of striatal neurogenesis enhances functional recovery in an adult animal model of neonatal hypoxic-ischemic brain injury.
Topics: Animals; Ataxia; Brain Damage, Chronic; Brain-Derived Neurotrophic Factor; Carotid Arteries; Cerebral Palsy; Corpus Striatum; Cytarabine; Disease Models, Animal; Drug Evaluation, Preclinical; Epidermal Growth Factor; Forelimb; Hemiplegia; Hypoxia; Hypoxia-Ischemia, Brain; Infusions, Intraventricular; Ligation; Mice; Mice, Inbred ICR; Neurogenesis; Random Allocation; Recovery of Function | 2010 |
Flt3-ITD alters chemotherapy response in vitro and in vivo in a p53-dependent manner.
Topics: Acute Disease; Animals; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Blotting, Western; Cytarabine; Disease Models, Animal; DNA Damage; Doxorubicin; Drug Resistance, Neoplasm; fms-Like Tyrosine Kinase 3; Gene Duplication; Humans; Leukemia, Myeloid; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myeloid-Lymphoid Leukemia Protein; Niacinamide; Phenylurea Compounds; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Sorafenib; Survival Analysis; Tandem Repeat Sequences; Tumor Suppressor Protein p53 | 2011 |
Activity of the multikinase inhibitor sorafenib in combination with cytarabine in acute myeloid leukemia.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; ATP-Binding Cassette Transporters; Benzenesulfonates; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromatography, High Pressure Liquid; Confounding Factors, Epidemiologic; Cytarabine; Disease Models, Animal; Drug Administration Schedule; Gene Expression Regulation, Neoplastic; Humans; Interleukin Receptor Common gamma Subunit; Leukemia, Myeloid, Acute; Mice; Mice, Inbred NOD; Mice, SCID; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Multidrug Resistance-Associated Proteins; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Signal Transduction; Sorafenib; Tandem Mass Spectrometry; Time Factors; Transplantation, Heterologous; Treatment Outcome | 2011 |
Ink4a and Arf are crucial factors in the determination of the cell of origin and the therapeutic sensitivity of Myc-induced mouse lymphoid tumor.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Blotting, Western; Bone Marrow Cells; Bone Marrow Transplantation; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p16; Cytarabine; Disease Models, Animal; Flow Cytometry; Genes, myc; Hematopoietic Stem Cells; Humans; Imidazoles; Mice; Mice, Knockout; Piperazines; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cells, B-Lymphoid; Tumor Suppressor Protein p14ARF | 2012 |
Recent and remote spatial memory in mice treated with cytosine arabinoside.
Topics: Animals; Antimetabolites, Antineoplastic; Behavior, Animal; Cytarabine; Disease Models, Animal; Male; Maze Learning; Memory; Memory Disorders; Mice; Mice, Inbred C57BL; Random Allocation; Spatial Behavior; Time Factors; Weight Loss | 2012 |
Synergy of sequential administration of a deglycosylated ricin A chain-containing combined anti-CD19 and anti-CD22 immunotoxin (Combotox) and cytarabine in a murine model of advanced acute lymphoblastic leukemia.
Topics: Animals; Antibodies, Monoclonal; Antigens, CD19; Cell Line, Tumor; Cytarabine; Disease Models, Animal; Drug Combinations; Drug Synergism; Humans; Immunotoxins; Mice; Mice, Inbred NOD; Neoplasm Staging; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Ricin; Sialic Acid Binding Ig-like Lectin 2; Xenograft Model Antitumor Assays | 2012 |
Ablation of proliferating cells in the CNS exacerbates motor neuron disease caused by mutant superoxide dismutase.
Topics: Amyotrophic Lateral Sclerosis; Animals; Cell Proliferation; Cytarabine; Disease Models, Animal; Disease Progression; Humans; Insulin-Like Growth Factor I; Interleukin-6; Mice; Mice, Transgenic; Microglia; Motor Neuron Disease; Superoxide Dismutase; Transforming Growth Factor beta | 2012 |
Altered spatial learning, cortical plasticity and hippocampal anatomy in a neurodevelopmental model of schizophrenia-related endophenotypes.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cytarabine; Disease Models, Animal; Dopamine; Endophenotypes; Hippocampus; Male; Maze Learning; Neurogenesis; Neuronal Plasticity; Norepinephrine; Rats; Rats, Sprague-Dawley; Schizophrenia; Serotonin | 2012 |
Overexpression of MN1 confers resistance to chemotherapy, accelerates leukemia onset, and suppresses p53 and Bim induction.
Topics: Animals; Antineoplastic Agents; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Cell Line, Tumor; Cytarabine; Disease Models, Animal; Doxorubicin; Gene Expression Regulation, Leukemic; Histones; Leukemia, Myeloid, Acute; Membrane Proteins; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Oncogene Proteins; Prognosis; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Trans-Activators; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2012 |
Synaptic plasticity, but not hippocampal neurogenesis, mediated the counteractive effect of wolfberry on depression in rats(1).
Topics: Animals; Anti-Inflammatory Agents; Antidepressive Agents; Antimetabolites, Antineoplastic; Corticosterone; Cytarabine; Depression; Disease Models, Animal; Disks Large Homolog 4 Protein; Golgi Apparatus; Hippocampus; Intracellular Signaling Peptides and Proteins; Lycium; Male; Membrane Proteins; Neurogenesis; Neuronal Plasticity; Plant Extracts; Rats; Rats, Sprague-Dawley; Stem Cells | 2012 |
[Effect of a novel aminosteroid on animal model of murine myelomonocytic leukemia].
Topics: Animals; Antimetabolites, Antineoplastic; Bone Marrow Cells; Cell Transformation, Neoplastic; Cytarabine; Disease Models, Animal; Female; Leukemia, Myelomonocytic, Acute; Male; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Random Allocation | 2000 |
[Experimental study on hemoperfusion to remove CIC in blood of rabbit with an affinity adsorbent II].
Topics: Animals; Antigen-Antibody Complex; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease Models, Animal; Doxorubicin; Female; Hemoperfusion; Immunosorbents; Male; Rabbits | 1999 |
Altered prepulse inhibition in rats treated prenatally with the antimitotic Ara-C: an animal model for sensorimotor gating deficits in schizophrenia.
Topics: Animals; Antineoplastic Agents; Apomorphine; Brain; Cytarabine; Disease Models, Animal; Dopamine Agonists; Drug Interactions; Female; Hallucinogens; Male; Maternal-Fetal Exchange; Phencyclidine; Pregnancy; Rats; Rats, Sprague-Dawley; Reflex, Startle; Schizophrenia | 2004 |
Activated neural stem cells contribute to stroke-induced neurogenesis and neuroblast migration toward the infarct boundary in adult rats.
Topics: Animals; Cell Division; Cell Movement; Cells, Cultured; Cytarabine; Disease Models, Animal; Doublecortin Protein; Infarction, Middle Cerebral Artery; Male; Microscopy, Electron; Middle Cerebral Artery; Neurons; Rats; Rats, Wistar; Stem Cells | 2004 |
Continuous cytosine-b-D-arabinofuranoside infusion reduces ectopic granule cells in adult rat hippocampus with attenuation of spontaneous recurrent seizures following pilocarpine-induced status epilepticus.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Differentiation; Cell Division; Cytarabine; Disease Models, Animal; Hippocampus; Immunohistochemistry; Injections, Intraventricular; Male; Neurons; Pilocarpine; Rats; Rats, Sprague-Dawley; Seizures; Status Epilepticus | 2004 |
The efficacy of diphtheria-growth factor fusion proteins is enhanced by co-administration of cytosine arabinoside in an immunodeficient mouse model of human acute myeloid leukemia.
Topics: Animals; Cytarabine; Disease Models, Animal; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-3; Leukemia, Myeloid; Mice; Mice, Inbred NOD; Mice, SCID; Recombinant Fusion Proteins | 2004 |
Anti-tumor efficacy of the nucleoside analog 1-(2-deoxy-2-fluoro-4-thio-beta-D-arabinofuranosyl) cytosine (4'-thio-FAC) in human pancreatic and ovarian tumor xenograft models.
Topics: Animals; Carcinoma; Cytarabine; Disease Models, Animal; Female; Mice; Mice, Nude; Ovarian Neoplasms; Pancreatic Neoplasms; Transplantation, Heterologous; Tumor Cells, Cultured | 2005 |
[Development of animal model with JC virus infection and the therapeutic study].
Topics: Animals; Antiviral Agents; Cells, Cultured; Collagen; Cytarabine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Delivery Systems; Genetic Therapy; Humans; JC Virus; Leukoencephalopathy, Progressive Multifocal; Male; Mice; Mice, Inbred BALB C; Mice, Nude; RNA, Small Interfering | 2005 |
The schedule-dependent effects of the novel antifolate pralatrexate and gemcitabine are superior to methotrexate and cytarabine in models of human non-Hodgkin's lymphoma.
Topics: Aminopterin; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Cycle; Cytarabine; Deoxycytidine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation, Preclinical; Gemcitabine; Humans; In Vitro Techniques; Lymphoma, Non-Hodgkin; Methotrexate; Mice; Mice, SCID; Time Factors; Xenograft Model Antitumor Assays | 2006 |
Neuronal apoptosis and gray matter heterotopia in microcephaly produced by cytosine arabinoside in mice.
Topics: Animals; Animals, Newborn; Antimetabolites, Antineoplastic; Apoptosis; Biomarkers; Bromodeoxyuridine; Calbindin 2; Cell Differentiation; Cell Movement; Cell Proliferation; Cerebral Cortex; Choristoma; Cytarabine; Disease Models, Animal; Mice; Mice, Inbred ICR; Microcephaly; Microtubule-Associated Proteins; Nerve Degeneration; Nervous System Malformations; Neurons; S100 Calcium Binding Protein G; Stem Cells | 2006 |
In vitro and in vivo pharmacological profile of UFP-512, a novel selective delta-opioid receptor agonist; correlations between desensitization and tolerance.
Topics: Animals; Antidepressive Agents; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Binding, Competitive; Cell Line, Tumor; Cytarabine; Depression; Desensitization, Immunologic; Disease Models, Animal; Drug Administration Schedule; Drug Tolerance; Endocytosis; Humans; Lomustine; Male; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitoxantrone; Neuroblastoma; Oligopeptides; Phosphorylation; Prednisone; Receptors, Opioid, delta; Signal Transduction; Swimming | 2007 |
Enhancement of the anti-tumor efficacy of a GM-CSF-secreting tumor cell immunotherapy in preclinical models by cytosine arabinoside.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Combined Modality Therapy; Cytarabine; Disease Models, Animal; Female; Flow Cytometry; Gene Transfer Techniques; Granulocyte-Macrophage Colony-Stimulating Factor; Immunologic Memory; Immunotherapy; Injections, Intraperitoneal; Leukemia, Myeloid, Acute; Luciferases; Lymphopenia; Mice; Mice, Congenic; Mice, Inbred C57BL; Neoplasm Transplantation; Phenotype; Survival Rate; Time Factors; Treatment Outcome | 2008 |
Pathological findings of adenine arabinoside (ARA-A) and cytarabine (ARA-C) in the treatment of herpes simplex encephalitis in rabbit model.
Topics: Animals; Brain; Cytarabine; Disease Models, Animal; Encephalitis, Arbovirus; Herpes Simplex; Optic Nerve; Rabbits; Simplexvirus; Vidarabine | 1982 |
[Studies on the behavioral pharmacology of TRH-T in cytosine arabinoside-induced ataxic mice: a comparison with genetically ataxic mice].
Topics: Age Factors; Animals; Ataxia; Cerebellum; Cytarabine; Disease Models, Animal; Male; Mice; Mice, Inbred ICR; Motor Activity; Thyrotropin-Releasing Hormone | 1983 |
Chemotherapeutic study on Yoshida sarcoma ascites cells implanted into the glandular stomach of rats. Monotherapy with 5-fluorouracil, methyl-CCNU, mitomycin C, adriamycin, and cytosine arabinoside, and combination therapy with respective two-drug combina
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Cytarabine; Disease Models, Animal; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Male; Mitomycin; Mitomycins; Rats; Rats, Inbred Strains; Sarcoma, Yoshida; Semustine; Stomach Neoplasms | 1983 |
Cell kinetic studies after high dose Ara-C and adriamycin treatment in a slowly growing rat leukemia model (BNML) for human acute myelocytic leukemia.
Topics: Animals; Cell Cycle; Cytarabine; Disease Models, Animal; Doxorubicin; Female; Flow Cytometry; Humans; Leukemia, Myeloid, Acute; Rats; Rats, Inbred BN | 1984 |
[Cytosine arabinoside-induced cerebellar ataxia model. (2). Roles of the 5-hydroxyindole compounds in the developmental cerebellum].
Topics: Animals; Cerebellar Ataxia; Cerebellum; Cytarabine; Disease Models, Animal; Indoles; Mice; Tissue Distribution | 1983 |
Protection against cytosine arabinoside-induced alopecia by minoxidil in a rat animal model.
Topics: Alopecia; Animals; Animals, Newborn; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Disease Models, Animal; Doxorubicin; Female; Male; Minoxidil; Rats; Rats, Sprague-Dawley | 1995 |
Protection against chemotherapy-induced alopecia by cyclosporin A in the newborn rat animal model.
Topics: Administration, Cutaneous; Alopecia; Animals; Animals, Newborn; Antineoplastic Agents; Cyclophosphamide; Cyclosporine; Cytarabine; Disease Models, Animal; Etoposide; Injections, Intraperitoneal; Rats; Rats, Sprague-Dawley | 1995 |
Lipopolysaccharide alters suckling rat liver glycogenolysis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Cytarabine; Disease Models, Animal; Glycogen; Indomethacin; Isoquinolines; Kupffer Cells; Lipopolysaccharides; Liver; Piperazines; Rats; Rats, Sprague-Dawley; Shock, Septic; Tetradecanoylphorbol Acetate | 1993 |
Protection by short-chain fatty acids against 1-beta-D-arabinofuranosylcytosine-induced intestinal lesions in germfree mice.
Topics: Administration, Oral; Animals; Cytarabine; Disease Models, Animal; Fatty Acids, Volatile; Fatty Liver; Intestinal Diseases; Intestinal Mucosa; Mice; Protective Agents | 1999 |
Antitumor activity of P-4055 (elaidic acid-cytarabine) compared to cytarabine in metastatic and s.c. human tumor xenograft models.
Topics: Animals; Antimetabolites, Antineoplastic; Biological Transport; Carcinoma; Carrier Proteins; Cytarabine; Disease Models, Animal; Drug Screening Assays, Antitumor; Fatty Acids, Unsaturated; Female; Humans; Leukemia L1210; Leukemia, Experimental; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Nucleoside Transport Proteins; Rats; Rats, Nude; Transplantation, Heterologous; Tumor Cells, Cultured | 1999 |
Leukemia cell lines resistant to cytosine arabinoside, cyclophosphamide or daunomycin are equally sensitive to the drug acetyldinaline as the parental cell line.
Topics: Animals; Antineoplastic Agents; Benzamides; Cyclophosphamide; Cytarabine; Daunorubicin; Disease Models, Animal; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Leukemia, Experimental; Phenylenediamines; Rats; Tumor Cells, Cultured | 2000 |
Cytotoxicity, cell-cycle perturbations and apoptosis in human tumor cells by lipophilic N4-alkyl-1-beta-D-arabinofuranosylcytosine derivatives and the new heteronucleoside phosphate dimer arabinocytidylyl-(5'-->5')-N4-octadecyl-1-beta-D-arabinofuranosylcy
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Cycle; Cytarabine; Deoxycytidine Kinase; Dimerization; Disease Models, Animal; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Mice; Mice, Nude; Phosphates; Phosphorylation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prodrugs; Transplantation, Heterologous | 2000 |
A new hamster fibrosarcoma model for in vitro/in vivo evaluation of cancer chemotherapeutic agents.
Topics: Ancitabine; Animals; Antineoplastic Agents; Azacitidine; Cell Division; Cell Line; Cells, Cultured; Clone Cells; Cricetinae; Cytarabine; Disease Models, Animal; Drug Therapy, Combination; Female; Fibrosarcoma; Mesocricetus; Sarcoma, Experimental | 1976 |
Chemotherapeutic remissions in Wistar Furth rat acute myelogenous leukemia: a model for human AML.
Topics: Animals; Antineoplastic Agents; Busulfan; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Dexamethasone; Disease Models, Animal; Doxorubicin; Leukemia, Experimental; Leukemia, Myeloid, Acute; Methotrexate; Rats; Remission, Spontaneous; Vinblastine; Vincristine | 1977 |
Evaluation of four antiviral agents in the treatment of herpes simplex encephalitis in a rat model.
Topics: Acetanilides; Adenine; Animals; Antiviral Agents; Arabinose; Brain; Cell Line; Culture Techniques; Cytarabine; Dimethylamines; Disease Models, Animal; Drug Evaluation; Encephalitis; Herpes Simplex; Idoxuridine; Inosine; Kidney; Lung; Nucleosides; Rabbits; Rats; Simplexvirus | 1975 |
Experimental infection with herpes simplex virus type 2 in newborn rats: Effects of treatment with iododeoxyuridine and cytosine arabinoside.
Topics: Animals; Animals, Newborn; Cytarabine; Disease Models, Animal; Herpesviridae Infections; Idoxuridine; Rats; Simplexvirus | 1975 |
Experimental herpes simplex virus encephalitis: Comparative effects of treatment with cytosine arabinoside and adenine arabinoside.
Topics: Animals; Brain; Cytarabine; Disease Models, Animal; Drug Evaluation, Preclinical; Encephalitis; Herpes Simplex; Mice; Purine Nucleosides; Simplexvirus; Vidarabine; Virus Replication | 1975 |
Effect of cytosine arabinoside and 5-iodo-2'-deoxyuridine on a cytomegalovirus infection in newborn mice.
Topics: Animals; Animals, Newborn; Cell Line; Cytarabine; Cytomegalovirus; Cytomegalovirus Infections; Disease Models, Animal; Idoxuridine; Mice | 1976 |
Intranasal challenge of mice with herpes simplex virus: an experimental model for evaluation of the efficacy of antiviral drugs.
Topics: Animals; Antiviral Agents; Cytarabine; Disease Models, Animal; Drug Evaluation, Preclinical; Encephalitis; Herpesviridae Infections; Idoxuridine; Interferons; Mice; Ribavirin; Simplexvirus; Vidarabine | 1976 |
The activity of iododeoxyuridine, adenine arabinoside, cytosine arabinoside, ribavirin and phosphonoacetic acid against herpes virus in the hairless mouse model.
Topics: Acetates; Animals; Cytarabine; Disease Models, Animal; Herpes Simplex; Idoxuridine; Kinetics; Mice; Mice, Nude; Organophosphonates; Ribavirin; Ribonucleosides; Simplexvirus; Vidarabine | 1977 |
Treatment of fatal disseminated vaccinia virus infection in immunosuppressed mice.
Topics: Animals; Antilymphocyte Serum; Cytarabine; Disease Models, Animal; Drug Evaluation, Preclinical; Idoxuridine; Immunosuppression Therapy; Injections, Intraperitoneal; Mice; T-Lymphocytes; Vaccinia; Vidarabine | 1977 |
Comparison of activity of herpes virus inhibitors.
Topics: Animals; Antiviral Agents; Cytarabine; Disease Models, Animal; Drug Evaluation, Preclinical; Herpes Simplex; Herpesviridae; Idoxuridine; Trifluridine; Vidarabine; Viral Plaque Assay; Virus Replication | 1977 |
Treatment of meningeal neoplasms.
Topics: Adult; Animals; Antineoplastic Agents; Brain Neoplasms; Carcinoma 256, Walker; Catheterization; Child; Cytarabine; Disease Models, Animal; Drug Therapy, Combination; Humans; Injections, Intraventricular; Injections, Spinal; Leukemia; Lumbosacral Region; Meninges; Methotrexate; Rats; Spinal Cord Neoplasms | 1977 |
Efficacy of adenine arabinoside (Ara-A) and cytarabine (Ara-C) in the treatment herpes encephalitis in animal model.
Topics: Animals; Cytarabine; Disease Models, Animal; Encephalitis; Herpes Simplex; Optic Atrophy; Rabbits; Vidarabine | 1978 |
Ocular antiviral therapy in perspective.
Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Corneal Ulcer; Cytarabine; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Idoxuridine; Keratitis, Dendritic; Mice; Rabbits; Trifluridine; Vidarabine | 1976 |
Experimental retinal dysplasia due to cytosine arabinoside.
Topics: Animals; Cytarabine; Disease Models, Animal; Male; Microscopy; Photoreceptor Cells; Rats; Retinal Diseases | 1977 |
Mouse myeloma. A model for studies of cell kinetics.
Topics: Alkylating Agents; Animals; Bone Marrow; Bone Marrow Cells; Bone Neoplasms; Cell Division; Cells, Cultured; Cyclophosphamide; Cytarabine; Disease Models, Animal; Kinetics; Melphalan; Methotrexate; Mice; Mice, Inbred BALB C; Myeloma Proteins; Neoplasms, Experimental; Plasmacytoma; Thymidine; Tritium; Vinblastine; Vincristine | 1975 |
Chemotherapy of a murine neuroblastoma model.
Topics: Animals; Cell Line; Cytarabine; Disease Models, Animal; Doxorubicin; Drug Administration Schedule; Mice; Mice, Inbred A; Neoplasms, Experimental; Neuroblastoma | 1975 |
IL-1 synergizes with ARA-C in aborting the development of chloroleukemia while protecting from ARA-C-induced alopecia in the rat model.
Topics: Alopecia; Animals; Cell Differentiation; Cytarabine; Disease Models, Animal; Drug Synergism; In Vitro Techniques; Interleukin-1; Leukemia, Myeloid; Neoplasm Transplantation; Rats | 1992 |
Experimental gastrointestinal and disseminated candidiasis in immunocompromised animals.
Topics: Animals; Candida albicans; Candidiasis; Cytarabine; Disease Models, Animal; Female; Gastrointestinal Diseases; Gentamicins; Immunocompromised Host; Intestinal Mucosa; Methylprednisolone; Rabbits; Vancomycin | 1992 |
Liposome suppression of proliferative vitreoretinopathy. Rabbit model using antimetabolite encapsulated liposomes.
Topics: Animals; Cytarabine; Disease Models, Animal; Drug Carriers; Eye Diseases; Half-Life; Liposomes; Rabbits; Retinal Diseases; Uracil Nucleotides; Vitreous Body | 1991 |
Interleukin 1 protects from cytosine arabinoside-induced alopecia in the rat model.
Topics: Alopecia; Animals; Cytarabine; Disease Models, Animal; Interleukin-1; Rats; Rats, Inbred Strains; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1991 |
Protection from chemotherapy-induced alopecia in a rat model.
Topics: Alopecia; Animals; Biological Products; Cytarabine; Disease Models, Animal; Immunologic Factors; Leukemia, Experimental; Rats; Rats, Inbred F344; Skin | 1990 |
The mechanism of cytosine arabinoside toxicity on quiescent astrocytes in vitro appears to be analogous to in vivo brain injury.
Topics: Animals; Astrocytes; Brain; Brain Injuries; Cell Differentiation; Cells, Cultured; Choline O-Acetyltransferase; Cholinergic Fibers; Cytarabine; Disease Models, Animal; Glutamate-Ammonia Ligase; Rats; Time Factors | 1988 |
Chronic silastic central venous catheterization for induction, maintenance and support of persistent granulocytopenia in rabbits.
Topics: Agranulocytosis; Animals; Catheterization, Central Venous; Catheters, Indwelling; Cytarabine; Disease Models, Animal; Female; Prospective Studies; Rabbits | 1988 |
In vivo studies on high-dose 1-beta-D-arabinofuranosylcytosine (HDara-C) and 1-beta-D-arabinofuranosyluracil (ara-U) with respect to pharmacokinetics, cell kinetics, and cytotoxicity in a rat myelocytic leukemia model (BNML).
Topics: Animals; Arabinofuranosyluracil; Cell Cycle; Colony-Forming Units Assay; Cytarabine; Cytidine Deaminase; Disease Models, Animal; Half-Life; Humans; Kinetics; Leukemia, Myeloid, Acute; Nucleoside Deaminases; Rats; Uridine | 1985 |
A two-stage therapeutic design in the spontaneous AKR lymphoma system.
Topics: Amides; Animals; Antineoplastic Agents; Azacitidine; Cyclic P-Oxides; Cyclophosphamide; Cytarabine; Disease Models, Animal; Drug Combinations; Female; Imidazoles; Lymphoma; Male; Mercaptopurine; Methotrexate; Mice; Mice, Inbred Strains; Oxazines; Prednisone; Remission, Spontaneous; Time Factors; Triazenes; Vincristine | 1972 |
Chemotherapeutic suppression of immune enhancement: a primary determinant of successful cancer therapy.
Topics: Animals; Antigens, Neoplasm; Antineoplastic Agents; B-Lymphocytes; Cell Survival; Child; Cyclophosphamide; Cytarabine; Disease Models, Animal; Graft Rejection; Graft vs Host Reaction; Humans; Immunity; Immunity, Cellular; Immunosuppression Therapy; Immunosuppressive Agents; Kinetics; Lymph Nodes; Neoplasms; Spleen; T-Lymphocytes; Transplantation Immunology | 1973 |
Potentially useful combinations of chemotherapy detected in mouse tumor systems.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Azauridine; Bleomycin; Camptothecin; Cyclic P-Oxides; Cyclophosphamide; Cytarabine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Ethylamines; Fluorouracil; Imidazoles; Leukemia L1210; Lung Neoplasms; Methotrexate; Mice; Neoplasms, Experimental; Oxazines; Piperazines; Procarbazine; Propane; Triazenes | 1974 |
Chemotherapy of Herpesvirus saimiri induced lymphoma-leukemia in the owl monkey.
Topics: Adenine; Animals; Arabinose; Cyclophosphamide; Cytarabine; Disease Models, Animal; Haplorhini; Herpesviridae; Hydrocortisone; Interferons; Leukemia, Lymphoid; Leukocyte Count; Lymphoma; Monkey Diseases; Oncogenic Viruses; Vincristine; Virus Replication | 1974 |
Chronic viral neuropathies: models for study and food for thought.
Topics: Animals; Antiviral Agents; Cattle; Chick Embryo; Cricetinae; Cytarabine; Cytomegalovirus; Dactinomycin; Deoxyuridine; Disease Models, Animal; DNA, Viral; Encephalitis Viruses; Friend murine leukemia virus; Humans; Imidazoles; Interferons; Mice; Mitomycins; Nervous System Diseases; Parainfluenza Virus 1, Human; Phenylalanine; Prions; Respirovirus; RNA Viruses; RNA, Viral; Vesicular stomatitis Indiana virus; Viral Interference; Virus Diseases | 1969 |
Effect of chemotherapy and-or head irradiation on survival of mice with intracranial glioma.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Copper; Cytarabine; Disease Models, Animal; Ependymoma; Female; Glioblastoma; Hematoporphyrins; Male; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Nitroso Compounds; Nitrosourea Compounds; Porphyrins; Radiotherapy; Urea | 1971 |
Spontaneous AK leukemia (lymphoma) as a model for human leukemias and lymphomas.
Topics: Animals; Cyclophosphamide; Cytarabine; Disease Models, Animal; Drug Combinations; Leukemia Virus, Murine; Leukemia, Experimental; Lymphoma; Mice; Mice, Inbred Strains; Remission, Spontaneous; Thymectomy; Time Factors; Vincristine | 1972 |
Experimental herpes simplex encephalitis. Treatment with pyrimidine nucleosides.
Topics: Animals; Brain Stem; Cytarabine; Disease Models, Animal; Encephalitis; Hemorrhage; Herpes Simplex; Hippocampus; Idoxuridine; Methods; Necrosis; Neurons; Olfactory Bulb; Rabbits; Simplexvirus; Time Factors | 1973 |
Combination chemotherapy for spontaneous AKR lymphoma.
Topics: Animals; Antineoplastic Agents; Biological Assay; Carmustine; Cyclohexanes; Cyclophosphamide; Cytarabine; Disease Models, Animal; Doxorubicin; Drug Therapy, Combination; Lymphoma; Methotrexate; Mice; Mice, Inbred AKR; Neoplasms, Experimental; Nitrosourea Compounds; Organ Size; Palmitic Acids; Prednisone; Remission, Spontaneous; Rodent Diseases; Spleen; Splenomegaly; Thymus Gland; Time Factors; Vincristine | 1974 |
Attempts at immunotherapy of 100 patients with acute lymphoid leukemia: some factors influencing results.
Topics: Animals; Bone Marrow Examination; Central Nervous System; Corynebacterium; Cytarabine; Cytotoxicity Tests, Immunologic; Disease Models, Animal; Female; Humans; Immune Sera; Immunotherapy; Leukemia, Experimental; Leukemia, Lymphoid; Lymphocyte Activation; Male; Methotrexate; Mice; Mice, Inbred AKR; Remission, Spontaneous | 1972 |
The rate of mutation of L5178Y asparagine-dependent mouse leukemia cells to asparagine independence and its biological consequences.
Topics: Animals; Asparagine; Carbon Isotopes; Cell Division; Cell Line; Cytarabine; Disease Models, Animal; Genes; Leukemia, Experimental; Leukemia, Lymphoid; Mice; Mutation; Phenotype; Time Factors | 1973 |
Comparative chemotherapy of AKR lymphoma and human hematological neoplasia.
Topics: Animals; Antineoplastic Agents; Biological Assay; Carmustine; Cyclohexanes; Cyclophosphamide; Cytarabine; Daunorubicin; Disease Models, Animal; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Fluorouracil; Hodgkin Disease; Humans; Leukemia; Leukemia L1210; Leukemia, Experimental; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma; Male; Mechlorethamine; Melphalan; Mice; Mice, Inbred AKR; Multiple Myeloma; Nitrosourea Compounds; Prednisone; Remission, Spontaneous; Vinblastine; Vincristine | 1974 |
An experimental model for the therapy of mouse neuroblastoma.
Topics: Animals; Cell Survival; Cytarabine; Dactinomycin; Disease Models, Animal; Mice; Neuroblastoma | 1973 |
The chemotherapy of herpes iritis with adenine arabinoside and cytarabine.
Topics: Animals; Arabinose; Chemical Phenomena; Chemistry; Cytarabine; Disease Models, Animal; Haplorhini; Iritis; Keratitis, Dendritic; Nucleosides; Rabbits | 1970 |
The effect of chemotherapeutic agents on the incorporation of DNA precursors by experimental brain tumors.
Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Bone Marrow; Brain; Brain Neoplasms; Carbon Isotopes; Carmustine; Cyclohexanes; Cytarabine; Deoxyuridine; Disease Models, Animal; DNA, Neoplasm; Dose-Response Relationship, Drug; Ependymoma; Glioma; Lymph Nodes; Male; Methotrexate; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosourea Compounds; Thymidine; Tritium | 1972 |
The treatment of acute lymphocytic leukemia.
Topics: Animals; Antineoplastic Agents; Asparaginase; Blood Platelets; Bone Marrow Cells; Cyclophosphamide; Cytarabine; Daunorubicin; Disease Models, Animal; Drug Synergism; Hemorrhage; Humans; Infections; Leukemia L1210; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Mice; Prednisone; Prognosis; Thrombocytopenia; Vincristine | 1970 |
Therapy of acute leukemia.
Topics: Adolescent; Animals; Antineoplastic Agents; Asparaginase; Bone Marrow; Bone Marrow Cells; Child; Cytarabine; Daunorubicin; Disease Models, Animal; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Mice; Remission, Spontaneous; Vincristine | 1970 |
Chemical suppression of primary and anamnestic maternal immunization of Rh-incompatible pregnancies. An animal model.
Topics: Animals; Antibody Formation; Cyclophosphamide; Cytarabine; Disease Models, Animal; Erythroblastosis, Fetal; Female; Immunosuppressive Agents; Pregnancy; Rats | 1970 |
A computer model for tumor growth and chemotherapy, and its application to L1210 leukemia treated with cytosine arabinoside (NSC-63878).
Topics: Animals; Computers; Cytarabine; Disease Models, Animal; Drug Resistance; Kinetics; Leukemia L1210; Mice; Mitosis; Neoplasm Transplantation | 1970 |
Implications of biochemical, cytokinetic, pharmacologic, and toxicologic relationships in the design of optimal therapeutic schedules.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Disease Models, Animal; DNA, Neoplasm; Fluorouracil; Half-Life; Hydroxyurea; In Vitro Techniques; Kinetics; Leukemia L1210; Mercaptopurine; Methotrexate; Mice; Mitosis; Nitrosourea Compounds; Thiosemicarbazones | 1970 |