cytarabine and Aging

cytarabine has been researched along with Aging in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199012 (37.50)18.7374
1990's5 (15.63)18.2507
2000's9 (28.13)29.6817
2010's6 (18.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Biol, MC; Galvain, D; Greco, S; Hugueny, I; Lenoir, D; Louisot, P1
Gangoso, E; Marques-Torrejon, MA; Pollard, SM1
Bixby, DL; Crouch, A; Marini, BL; Nachar, VR; Perissinotti, AJ; Scappaticci, GB; Talpaz, M; Uebel, JR; Vulaj, V1
Cooper, R; Hardy, R; Kuh, D; Moore, A; Richards, M1
Azizi, AA; Chocholous, M; Höferl, M; Jäger, W; Peyrl, A; Sauermann, R; Slavc, I1
Boehm, U; Bourque, CW; Dimou, L; Djogo, T; Gillon, CJ; Kim, JH; Kokoeva, MV; Kryzskaya, D; Liu, X; Mingay, A; Robins, SC; Schneider, S; Storch, KF; Stroh, T1
Archer, LE; Damon, LE; Hurd, D; Larson, RA; Linker, CA; Owzar, K; Powell, B1
Alibhai, SM; Brandwein, JM; Breunis, H; Buckstein, R; Gupta, V; Li, M; Minden, MD; Mohamedali, H; Timilshina, N; Tomlinson, G1
Sekeres, MA; Stone, R1
Alvarez-Buylla, A; Caporaso, GL; Chao, MV; Lim, DA1
Cecconi, F; D'Sa, C; Flavell, RA; Klocke, BJ; Korsmeyer, SJ; Lindsten, T; Roth, KA; Thompson, CB1
Barone, TA; Maslov, AY; Plunkett, RJ; Pruitt, SC1
Büchner, T; Creutzig, U; Döhner, H; Reinhardt, D; Sauerland, MC; Schlenk, RF; Zimmermann, M1
Freireich, EJ1
Ferrell, J; Gray, LE; Kavlock, RJ; Ostby, J1
Caporale, R; Cervi, L; Ciolli, S; Giuliani, G; Leoni, F; Pascarella, A; Rossi Ferrini, P; Salti, F1
Rivera, AJ; Seger, R; Yablonka-Reuveni, Z1
Appelbaum, FR; Banker, DE; Cooper, JJ; Garrido, SM; Kopecky, K; Willman, CL1
Amenomori, T; Atogami, S; Fukushima, T; Hayashibara, T; Honda, M; Ikeda, S; Jinnai, I; Kuriyama, K; Kusano, M; Matsuo, T; Miyazaki, Y; Momita, S; Nagai, K; Nonaka, H; Soda, H; Taguchi, J; Tomonaga, M; Toriya, K; Yoshida, S; Yoshida, Y1
Adriansson, M; Arheden, K; Axelsson, P; Billström, R; Cervin, A; Fioretos, T; Johansson, B; Mitelman, F; Olofsson, T; Strömbeck, B; Tanke, HJ1
Kasubuchi, Y; Kusonoki, T; Shimada, M; Wakaizumi, S1
Fenech, M; Neville, S1
Baltimore, D; Chun, JJ; Jaenisch, R; Oettinger, MA; Schatz, DG1
Bearden, JD; Capizzi, RL; Jackson, DV; Lyerly, ES; Morgan, TM; Muss, HB; Powell, BL; Richards, F; Rosenbaum, DL; White, DR1
Nakada, H; Nishimura, M; Nonaka, K; Ohmoto, E; Ohnoshi, T; Takahashi, I1
Matsui, K1
Bordessoule, D; Brière, J; Castaigne, S; Colombat, P; Donadio, D; Drony, S; Guy, H; Sigaux, F; Solal Celigny, P; Tilly, H1
Capizzi, RL; Cooper, MR; Jackson, DV; Muss, HB; Powell, BL; Richards, F; Spurr, CL; Stuart, JJ; White, DR; Zekan, PJ1
Coccia, PF; Herzig, GP; Herzig, RH; Lazarus, HM; Wolff, SN1
Capizzi, RL; Cheng, E; Cheng, YC; Kute, T; Rathmell, JP; White, JC; Yang, JL1
Castaigne, S; Daniel, MT; Degos, L; Sigaux, F; Tilly, H1
Goldberg, AL; Goldspink, DF1

Reviews

5 review(s) available for cytarabine and Aging

ArticleYear
Older adults with acute myeloid leukemia.
    Current oncology reports, 2002, Volume: 4, Issue:5

    Topics: Acute Disease; Age Factors; Aged; Aging; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Cytarabine; Drug Tolerance; Growth Substances; Humans; Leukemia, Myeloid; Recurrence; Remission Induction

2002
Methods for evaluating response to treatment in adult acute leukemia.
    Blood cells, 1983, Volume: 9, Issue:1

    Topics: Acute Disease; Adult; Aging; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Clinical Trials as Topic; Cytarabine; Doxorubicin; Drug Therapy, Combination; Glycopeptides; Humans; Leukemia; Models, Biological; Peptide Fragments; Prednisone; Pro-Opiomelanocortin; Prognosis; Prospective Studies; Regression Analysis; Vincristine

1983
Attenuated-dose idarubicin in acute myeloid leukaemia of the elderly: pharmacokinetic study and clinical results.
    British journal of haematology, 1995, Volume: 90, Issue:1

    Topics: Adult; Aged; Aging; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Etoposide; Female; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Survival Rate

1995
Sequential high-dose ara-C and asparaginase in the therapy of previously treated and untreated patients with acute leukemia.
    Seminars in oncology, 1985, Volume: 12, Issue:2 Suppl 3

    Topics: Aging; Animals; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Asparaginase; Child; Clinical Trials as Topic; Cytarabine; Daunorubicin; DNA; Dose-Response Relationship, Drug; Drug Resistance; Humans; Kinetics; Leukemia; Leukemia, Lymphoid; Middle Aged; Time Factors

1985
Dose-related pharmacologic effects of high-dose ara-C and its self-potentiation.
    Seminars in oncology, 1985, Volume: 12, Issue:2 Suppl 3

    Topics: Aging; Animals; Arabinofuranosyluracil; Biological Transport; Bone Marrow; Cell Line; Cell Membrane; Clinical Trials as Topic; Cytarabine; DNA; Dose-Response Relationship, Drug; Drug Resistance; Half-Life; Humans; Interphase; Leukemia; Leukemia L5178; Time Factors

1985

Trials

5 trial(s) available for cytarabine and Aging

ArticleYear
Pharmacokinetics and toxicity of intrathecal liposomal cytarabine in children and adolescents following age-adapted dosing.
    Clinical pharmacokinetics, 2014, Volume: 53, Issue:2

    Topics: Adolescent; Aging; Antimetabolites, Antineoplastic; Brain Neoplasms; Child; Child, Preschool; Cytarabine; Female; Humans; Injections, Spinal; Liposomes; Male

2014
Attenuated-dose idarubicin in acute myeloid leukaemia of the elderly: pharmacokinetic study and clinical results.
    British journal of haematology, 1995, Volume: 90, Issue:1

    Topics: Adult; Aged; Aging; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Etoposide; Female; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Survival Rate

1995
Low-dose ara-C therapy for acute myelogenous leukemia in elderly patients.
    Leukemia, 1989, Volume: 3, Issue:1

    Topics: Aged; Aging; Clinical Trials as Topic; Cytarabine; Drug Administration Schedule; Female; Granulocytes; Hemorrhage; Humans; Infections; Injections, Subcutaneous; Leukemia, Myeloid, Acute; Leukopenia; Male; Middle Aged; Prospective Studies; Remission Induction; Thrombocytopenia

1989
Sequential high-dose ara-C and asparaginase in the therapy of previously treated and untreated patients with acute leukemia.
    Seminars in oncology, 1985, Volume: 12, Issue:2 Suppl 3

    Topics: Aging; Animals; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Asparaginase; Child; Clinical Trials as Topic; Cytarabine; Daunorubicin; DNA; Dose-Response Relationship, Drug; Drug Resistance; Humans; Kinetics; Leukemia; Leukemia, Lymphoid; Middle Aged; Time Factors

1985
Dose-related pharmacologic effects of high-dose ara-C and its self-potentiation.
    Seminars in oncology, 1985, Volume: 12, Issue:2 Suppl 3

    Topics: Aging; Animals; Arabinofuranosyluracil; Biological Transport; Bone Marrow; Cell Line; Cell Membrane; Clinical Trials as Topic; Cytarabine; DNA; Dose-Response Relationship, Drug; Drug Resistance; Half-Life; Humans; Interphase; Leukemia; Leukemia L5178; Time Factors

1985

Other Studies

25 other study(ies) available for cytarabine and Aging

ArticleYear
Role of insulin and nutritional factors in intestinal glycoprotein fucosylation during postnatal development.
    The American journal of physiology, 1998, Volume: 275, Issue:5

    Topics: Aging; alpha-Fetoproteins; Animal Nutritional Physiological Phenomena; Animals; Asialoglycoproteins; Fetuins; Fucosyltransferases; Galactoside 2-alpha-L-fucosyltransferase; Gene Expression Regulation, Developmental; Glycoproteins; Guanosine Diphosphate Fucose; Insulin; Intestinal Mucosa; Male; Microvilli; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley

1998
Modelling glioblastoma tumour-host cell interactions using adult brain organotypic slice co-culture.
    Disease models & mechanisms, 2018, 02-22, Volume: 11, Issue:2

    Topics: Aging; Animals; Antigens, CD; Biomarkers, Tumor; Brain; Brain Neoplasms; Cell Communication; Cell Proliferation; Coculture Techniques; Culture Media, Serum-Free; Cytarabine; Dacarbazine; Disease Models, Animal; Endothelial Cells; Glioblastoma; Humans; Mice, Inbred C57BL; Neoplastic Stem Cells; Neural Stem Cells; Organ Specificity; Stem Cell Niche; Temozolomide; Tumor Microenvironment; Xenograft Model Antitumor Assays

2018
Outcomes of previously untreated elderly patients with AML: a propensity score-matched comparison of clofarabine vs. FLAG.
    Annals of hematology, 2018, Volume: 97, Issue:4

    Topics: Adenine Nucleotides; Aged; Aged, 80 and over; Aging; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Case-Control Studies; Chemical and Drug Induced Liver Injury; Clofarabine; Cohort Studies; Combined Modality Therapy; Cost Savings; Costs and Cost Analysis; Cytarabine; Granulocyte Colony-Stimulating Factor; Hospital Costs; Humans; Incidence; Induction Chemotherapy; Length of Stay; Leukemia, Myeloid, Acute; Michigan; Middle Aged; Neutropenia; Propensity Score; Retrospective Studies; Survival Analysis; Tertiary Care Centers; Vidarabine

2018
Age at menopause and lifetime cognition: Findings from a British birth cohort study.
    Neurology, 2018, 05-08, Volume: 90, Issue:19

    Topics: Adult; Aged; Aging; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cognition; Cohort Studies; Cyclophosphamide; Cytarabine; Doxorubicin; Female; Humans; Memory; Menopause; Middle Aged; Neuropsychological Tests; Nimustine; Socioeconomic Factors; United Kingdom; Verbal Learning

2018
Adult NG2-Glia Are Required for Median Eminence-Mediated Leptin Sensing and Body Weight Control.
    Cell metabolism, 2016, 05-10, Volume: 23, Issue:5

    Topics: Aging; Animals; Anorexia; Arcuate Nucleus of Hypothalamus; Body Weight; Cell Proliferation; Cytarabine; Dendrites; Electrophysiological Phenomena; Female; Gene Deletion; Leptin; Male; Median Eminence; Mice; Microglia; Mitosis; Neuroglia; Obesity; Phenotype; Receptors, Leptin; Signal Transduction; Weight Gain

2016
Auto-SCT for AML in second remission: CALGB study 9620.
    Bone marrow transplantation, 2009, Volume: 44, Issue:6

    Topics: Adult; Aged; Aging; Antigens, CD34; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Etoposide; Female; Humans; Ideal Body Weight; Infusions, Intravenous; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Peripheral Blood Stem Cell Transplantation; Remission Induction; Transplantation, Autologous; Treatment Outcome; Treatment Refusal; Young Adult

2009
Older age is associated with similar quality of life and physical function compared to younger age during intensive chemotherapy for acute myeloid leukemia.
    Leukemia research, 2012, Volume: 36, Issue:10

    Topics: Activities of Daily Living; Adult; Age Factors; Aged; Aged, 80 and over; Aging; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Longitudinal Studies; Male; Middle Aged; Prospective Studies; Quality of Life; Treatment Outcome; Young Adult

2012
Telomerase activity in the subventricular zone of adult mice.
    Molecular and cellular neurosciences, 2003, Volume: 23, Issue:4

    Topics: Aging; Animals; Animals, Newborn; Cell Differentiation; Cell Division; Cell Movement; Cells, Cultured; Cytarabine; Mice; Neurons; Olfactory Bulb; Stem Cells; Telencephalon; Telomerase

2003
Caspase regulation of genotoxin-induced neural precursor cell death.
    Journal of neuroscience research, 2003, Nov-01, Volume: 74, Issue:3

    Topics: Aging; Animals; Apoptotic Protease-Activating Factor 1; bcl-2 Homologous Antagonist-Killer Protein; Blotting, Western; Caspases; Catecholamines; Cell Death; Cells, Cultured; Cytarabine; DNA Damage; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Female; Imidazolines; Immunohistochemistry; Immunosuppressive Agents; Membrane Proteins; Mice; Mice, Inbred Strains; Mice, Knockout; Mutagens; Neurons; Pregnancy; Proteins; Reactive Oxygen Species; Telencephalon; Tumor Suppressor Protein p53; X-Rays

2003
Neural stem cell detection, characterization, and age-related changes in the subventricular zone of mice.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Feb-18, Volume: 24, Issue:7

    Topics: Administration, Oral; Aging; Animals; Antigens, Differentiation; Bromodeoxyuridine; Cell Count; Cell Cycle; Cell Division; Cells, Cultured; Cytarabine; Deoxyuridine; Glial Fibrillary Acidic Protein; Idoxuridine; Intermediate Filament Proteins; Lateral Ventricles; Male; Mice; Minichromosome Maintenance Complex Component 2; Nerve Tissue Proteins; Nestin; Neurons; Nuclear Proteins; Stem Cells

2004
Significance of age in acute myeloid leukemia patients younger than 30 years: a common analysis of the pediatric trials AML-BFM 93/98 and the adult trials AMLCG 92/99 and AMLSG HD93/98A.
    Cancer, 2008, Feb-01, Volume: 112, Issue:3

    Topics: Adolescent; Adult; Aging; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Bone Marrow; Child; Child, Preschool; Clinical Trials as Topic; Cytarabine; Etoposide; Female; Humans; Idarubicin; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Male; Prognosis; Risk Factors; Survival Analysis; Treatment Outcome

2008
Assessment of the utility of postnatal testing following prenatal exposure to forty chemicals.
    Progress in clinical and biological research, 1983, Volume: 140

    Topics: Abnormalities, Drug-Induced; Aging; Animals; Body Weight; Cricetinae; Cytarabine; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; Evaluation Studies as Topic; Female; Gestational Age; Herbicides; Male; Mice; Mortality; Motor Activity; Phenyl Ethers; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Reproduction; Teratogens

1983
Fibroblast growth factor promotes recruitment of skeletal muscle satellite cells in young and old rats.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1999, Volume: 47, Issue:1

    Topics: Aging; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Cell Division; Cytarabine; Fibroblast Growth Factor 2; Hepatocyte Growth Factor; Immunoblotting; Immunohistochemistry; Male; Muscle Development; Muscle, Skeletal; MyoD Protein; Myogenin; Myosins; Proliferating Cell Nuclear Antigen; Protein Isoforms; Rats; Rats, Sprague-Dawley

1999
Blasts from elderly acute myeloid leukemia patients are characterized by low levels of culture- and drug-induced apoptosis.
    Leukemia research, 2001, Volume: 25, Issue:1

    Topics: Acute Disease; Adult; Aged; Aging; Antibiotics, Antineoplastic; Antigens, CD34; Antimetabolites, Antineoplastic; Apoptosis; Bone Marrow Cells; Cell Cycle; Cytarabine; Daunorubicin; G2 Phase; Humans; Leukemia, Myeloid; Middle Aged; Mitosis; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-bcl-2; S Phase; Tumor Cells, Cultured

2001
De novo acute myeloid leukemia in the elderly; a consistent fraction of long-term survivors by standard-dose chemotherapy.
    Leukemia research, 2001, Volume: 25, Issue:1

    Topics: Acute Disease; Aged; Aged, 80 and over; Aging; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Karyotyping; Leukemia, Myeloid; Male; Mercaptopurine; Middle Aged; Prognosis; Treatment Outcome; Tretinoin

2001
Isodicentric 7p, idic(7)(q11.2), in acute myeloid leukemia associated with older age and favorable response to induction chemotherapy: a new clinical entity?
    Genes, chromosomes & cancer, 2001, Volume: 30, Issue:3

    Topics: Aged; Aged, 80 and over; Aging; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chromosome Banding; Chromosomes, Human, Pair 7; Cytarabine; Female; Humans; Idarubicin; In Situ Hybridization, Fluorescence; Isochromosomes; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Male; Remission Induction; Thioguanine

2001
Cytarabine and its effect on cerebellum of suckling mouse.
    Archives of neurology, 1975, Volume: 32, Issue:8

    Topics: Aging; Animals; Animals, Newborn; Cerebellum; Cytarabine; Mice

1975
Conversion of excision-repairable DNA lesions to micronuclei within one cell cycle in human lymphocytes.
    Environmental and molecular mutagenesis, 1992, Volume: 19, Issue:1

    Topics: Adult; Aging; Cell Cycle; Cells, Cultured; Cytarabine; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Humans; Lymphocytes; Methylnitrosourea; Micronuclei, Chromosome-Defective; Micronucleus Tests; Middle Aged; Regression Analysis

1992
The recombination activating gene-1 (RAG-1) transcript is present in the murine central nervous system.
    Cell, 1991, Jan-11, Volume: 64, Issue:1

    Topics: Aging; Animals; Base Sequence; Brain; Cell Division; Cell Line; Chromosome Mapping; Cytarabine; Genes; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Neurons; Nucleic Acid Hybridization; Oligonucleotide Probes; Organ Specificity; Polymerase Chain Reaction; Recombination, Genetic; RNA Probes; Teratoma; Transcription, Genetic; Tretinoin

1991
[Influences of aging on clinical pictures of hematological diseases: hypoplastic leukemia in the aged].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 1987, Volume: 24, Issue:2

    Topics: Aged; Aging; Antineoplastic Agents; Cytarabine; Humans; Leukemia, Myeloid, Acute

1987
[Changes of ataxia, spontaneous movement and the cerebellar noradrenaline system with aging in ataxic mice].
    Jikken dobutsu. Experimental animals, 1986, Volume: 35, Issue:1

    Topics: Aging; Animals; Ataxia; Cerebellum; Cytarabine; Male; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C3H; Motor Activity; Norepinephrine; Organ Size

1986
[Treatment of malignant hemopathies with aracytine in low doses. Analysis of 159 cases].
    Nouvelle revue francaise d'hematologie, 1985, Volume: 27, Issue:6

    Topics: Aged; Aging; Cytarabine; Humans; Leukemia, Myeloid, Acute; Middle Aged; Myeloproliferative Disorders; Retrospective Studies

1985
Central nervous system toxicity with high-dose cytosine arabinoside.
    Seminars in oncology, 1985, Volume: 12, Issue:2 Suppl 3

    Topics: Acute Disease; Aging; Central Nervous System Diseases; Combined Modality Therapy; Cytarabine; Drug Evaluation; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphoma; Middle Aged; Whole-Body Irradiation

1985
Treatment of leukemia with low-dose ara-C: a study of 160 cases.
    Seminars in oncology, 1985, Volume: 12, Issue:2 Suppl 3

    Topics: Acute Disease; Aged; Aging; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia

1985
Problems in the use of (Me- 3H) thymidine for the measurement of DNA synthesis.
    Biochimica et biophysica acta, 1973, Apr-11, Volume: 299, Issue:4

    Topics: Aging; Animals; Brain; Carbon Isotopes; Cycloheximide; Cytarabine; Dactinomycin; Diaphragm; DNA; Fasting; Kidney; Kinetics; Leucine; Lipids; Liver; Liver Regeneration; Male; Methods; Protein Biosynthesis; Rats; RNA; Thymidine; Tritium

1973