cytarabine and Acute Myelogenous Leukemia

cytarabine has been researched along with Acute Myelogenous Leukemia in 3877 studies

Research

Studies (3,877)

TimeframeStudies, this research(%)All Research%
pre-19901116 (28.79)18.7374
1990's610 (15.73)18.2507
2000's508 (13.10)29.6817
2010's1138 (29.35)24.3611
2020's505 (13.03)2.80

Authors

AuthorsStudies
Chou, TH; Kessel, D; Khilanani, P2
Choi, SJ; Choi, SU; Han, SY; Kim, YC; Lee, SD; Moon, MJ1
Bell-Horwath, TR; Li, G; Merino, EJ; Mulloy, JC; Thowfeik, FS; Vadukoot, AK; Wunderlich, M1
Atallah, G; Aycinena, A; Basham, S; Bellamacina, C; Burger, MT; Castillo, J; Chan, J; Chen, MY; Dai, Y; Ding, Y; Feucht, P; Fritsch, C; Garcia, PD; Ginn, E; Han, W; Holash, J; Huh, K; Kauffmann, A; Lambert, A; Lan, J; Langowski, JL; Lindvall, MK; Mathur, M; Muller, K; Nishiguchi, G; Pfister, E; Simmons, R; Tamez, V; Vanasse, KG; Wang, Y; Zang, R; Zavorotinskaya, T; Zhang, Y1
Chen, Y; Guo, H; Jin, J; Jin, Q; Li, B; Li, T; Lin, G; Ling, J; Lu, S; Lu, T; Wang, Y; Wang, Z; Yang, T; Yao, C; Yuan, H; Zhang, L; Zhi, Y1
Feng, R; Li, J; Liu, H; Ning, S; Pei, L; Sun, J; Wang, T; Xing, B; Zhao, Y; Zhu, X1
Braniecki, M; Gok Yavuz, B; Hwang, J; Quigley, JG; Singh, N; Tsoukas, MM1
Anderson, E; Cox, C; Gynn, LE; May, JE; Robinson, G; Upstill-Goddard, G; Wexler, SA1
Advani, AS; Becker, PS; Bixby, DL; DeAngelo, DJ; Feldman, EJ; Jonas, BA; Liesveld, JL; Magnani, JL; Marlton, P; O'Dwyer, ME; Thackray, HM1
Almlöf, I; Calderón-Montaño, JM; Centio, A; Erkers, T; Estruch, M; Friedrich, S; Gad, H; Garnett, MJ; Göktürk, C; Helleday, T; Henriksson, M; Heshmati, Y; Höglund, A; Koolmeister, T; Lehmann, S; Nagesh Danda, A; Östling, P; Pham, TM; Rasti, A; Sandvall, T; Sanjiv, K; Scobie, M; Seashore-Ludlow, B; Struyf, N; Theilgaard-Mönch, K; Tsuber, V; Våtsveen, TK; Visnes, T; Walfridsson, J; Wallner, O; Warpman Berglund, U; Wiita, E1
Ariti, C; Burnett, AK; Clark, RE; Copland, M; Dennis, M; Gilkes, A; Hemmaway, C; Hills, RK; Knapper, S; Mehta, P; Radia, R; Russell, N; Thomas, IF; Upton, L1
Daver, N; DiNardo, C; Konopleva, M; Saxena, K1
Alakel, N; Bornhäuser, M; Chemnitz, J; Döhner, H; Döhner, K; Fransecky, L; Gaidzik, V; Germing, U; Götze, KS; Haas, R; Hänel, M; Hanoun, M; Henning, L; Heuser, M; Holderried, TAW; Holtick, U; Jehn, CF; Kaiser, U; Kobbe, G; Koch, K; Kraus, S; Krause, SW; Kriege, O; Krüger, W; Lauseker, M; Middeke, JM; Morgner, A; Neuerburg, C; Platzbecker, U; Rautenberg, C; Röhnert, MA; Röllig, C; Sauer, T; Schäfer-Eckart, K; Schetelig, J; Schliemann, C; Scholl, S; Schröder, J; Schroeder, T; Severmann, J; Sockel, K; Stelljes, M; Stölzel, F; Thol, F; Unglaub, JM; Verbeek, M; Vucinic, V; Wagner-Drouet, E; Wass, M1
Fleischmann, M; Frietsch, JJ; Glaser, A; Hammersen, J; Hilgendorf, I; Hochhaus, A; Mühleck, R; Sayer, HG; Schnetzke, U; Scholl, S; Schrenk, K1
Kubal, T; Lee, J; Li, W; McCarthy, K; Richter, K1
Garcia-Manero, G; Jabbour, EJ; Jain, N; Kantarjian, HM; Ravandi, F; Welch, MA; Wierda, WG1
He, Y; Li, X; Long, B; Sun, Y; Wen, R; Zhang, J; Zhang, X1
Casper, J; Frietsch, JJ; Hilgendorf, I; Hochhaus, A; Köhne, CH; O'Hagan Henderson, S1
Leiby, BE; Schmucker, AM; Wilde, L1
Chen, Q; Chen, Y; Hu, J; Li, J; Li, X; Mao, Y; Shen, Y; Sheng, Y; Wang, L; Weng, X; Wu, J; Wu, M; You, J; Zhang, Y; Zhao, H; Zheng, Y1
Augeri, S; Aydin, S; Bracci, C; D'Ardia, S; Ferrero, E; Funaro, A; Marchisio, S; Massaia, M; Ortolan, E; Yakymiv, Y1
Caldwell, KJ; Farrar, JE; Federico, SM; Hu, Y; Lei, S; Lewis, S; Nichols, KE; Onciu, M; Ribeiro, RC; Rubnitz, JE; Salek, M; Takemoto, CM; Triplett, BM; Wlodarski, MW; Zhang, J1
Anthony, S; Bearss, D; Bergua Burgues, JM; Bhatnagar, B; Bhatt, VR; Castillo, TBD; Dalovisio, A; Dillon, R; Douglas Smith, B; Esteve, J; Fine, G; Frankfurt, O; Lee, DJ; Lin, TL; Litzow, MR; Mehta, P; Montesinos, P; Nazha, A; Schriber, J; Vicente, MV; Vigil, CE; Wang, ES; Yair Levy, M; Yee, K; Zeidner, JF1
Alonzo, TA; Aplenc, R; de Bont, ESJM; Gamis, AS; Gerbing, RB; Hoff, FW; Horton, TM; Jenkins, GN; Kolb, EA; Kornblau, SM; Meshinchi, S; Qiu, Y; van Dijk, AD1
Gai, Y; Lin, H; Liu, F; Liu, S; Lv, J; Su, Y; Wang, G; Wang, Y; Zhao, Q1
Alric, C; Bérard, E; Bertoli, S; Bidet, A; de Grande, AC; Delabesse, E; Dumas, PY; Galtier, J; Klein, E; Lechevalier, N; Leguay, T; Luquet, I; Pigneux, A; Récher, C; Rieu, JB; Sarry, A; Tavitian, S; Vergez, F; Vial, JP1
Coombs, CC; DeZern, AE; Foster, MC; Gojo, I; Ivanova, A; Jamieson, K; Knaus, HA; Levis, MJ; Luznik, L; Mazziotta, F; McKinnon, KP; Montgomery, ND; Moore, D; Mukhopadhyay, R; Prince, GT; Serody, JS; Smith, BD; Van Deventer, H; Vincent, BG; Webster, JA; Wilkinson, AD; Zeidner, JF1
Kaspers, GJL; Kipng'etich, M; Klein, K; Langat, S; Mostert, S; Njuguna, F; Olbara, G; van Weelderen, RE; Vik, TA1
Álamo, P; Alba-Castellón, L; Aviñó, A; Casanova, I; Cedó, L; Eritja, R; Falgàs, A; Gallardo, A; García-León, A; Mangues, R; Núñez, Y; Pallarès, V; Sánchez-García, L; Serna, N; Sierra, J; Unzueta, U; Vázquez, E; Villaverde, A1
Kuo, DJ; Le Floch, N; Spies, JM; Wong, V1
Michaelis, LC1
Luger, SM3
Itsumi, M; Kajikawa, M; Kato, H; Kawai, C; Kitakaze, K; Kuribayashi, F; Miyano, K; Okamoto, S; Yamauchi, A1
Thol, F2
Guo, Z; Liu, L; Liu, P; Ren, X; Wang, F; Xu, W; Xu, Y; Zhang, H; Zhang, S; Zheng, L1
Burnett, A; Dennis, M; Hills, R; Kjeldsen, L; Russell, N1
Arnan, M; Bargay, J; Bataller, A; Brunet, S; Castaño-Díez, S; Coll, R; Colomer, D; Costa, D; de Llano, MPQ; Diaz-Beyá, M; Escoda, L; Esteban, D; Esteve, J; Gallardo, D; Garcia-Guiñon, A; Garrido, A; Guijarro, F; López-Guerra, M; Merchan, BM; Mozas, P; Nomdedéu, JF; Oliver-Caldés, A; Oñate, G; Pratcorona, M; Rivero, A; Rozman, M; Salamero, O; Sampol, A; Sierra, J; Tormo, M; Vall-Llovera, F; Vives, S; Zamora, L1
Cai, H; Ekblom, M; Johansson, AS; Kondo, M; Qian, H; Sandhow, L; Sasaki, T; Tryggvason, K; Ungerstedt, J; Walfridsson, J; Xiao, P; Zawacka-Pankau, J1
Shimony, S; Stahl, M; Stone, RM1
Rowe, JM4
Al-Mansour, Z; Alonzo, TA; Aplenc, R; Cao, X; Cogle, C; Elsayed, AH; Gamis, A; Kolb, EA; Lamba, JK; Meshinchi, S; Mitra, AK; Pounds, S; Raimondi, S; Ribeiro, RC; Rubnitz, J; Wu, H1
DiNardo, CD; Pollyea, DA1
Jordheim, LP1
Assis-Mendonça, GR; Bueno, MLP; da Silva, JAF; Duarte, ASS; Ferro, KP; Pericole, FV; Rego, EM; Roversi, FM; Saad, STO; Shiraishi, RN; Torello, CO1
Akahoshi, Y; Gomyo, A; Kako, S; Kameda, K; Kanda, Y; Kawamura, M; Kawamura, S; Kimura, SI; Kusuda, M; Matsumi, S; Misaki, Y; Nakamura, Y; Nakasone, H; Okada, Y; Sato, M; Takeshita, J; Tamaki, M; Tanihara, A; Wada, H; Yoshimura, K; Yoshino, N1
Chen, Q; Chen, X; Liu, J; Luo, W; Sun, H; Zhou, G1
Kuang, P; Liu, T; Qin, Y1
Cai, X; Geng, L; Han, Y; Liu, H; Liu, X; Sun, Z; Tang, B; Tong, J; Wang, L; Wang, X; Xue, L; Zhang, L; Zhao, N; Zheng, C; Zhou, L; Zhu, W; Zhu, X1
Fleischmann, M; Frietsch, JJ; Hammersen, J; Hilgendorf, I; Hochhaus, A; Prims, F; Schnetzke, U; Scholl, S; Schrenk, K; Thiede, C1
Strickland, SA; Vey, N1
Casasnovas, NM; Castells, G; Manzaneque, A; Muntañola, A1
Dunham, N; Fan, H; Garrett-Bakelman, FE; Prajapati, SC1
Argüello, RJ; Aroua, N; Avet-Loiseau, H; Boet, E; Bosc, C; Bousard, A; Cabon, F; Cognet, G; Farge, T; Fournié, JJ; Fovez, Q; Gadaud, N; Gotanègre, M; Jarrou, L; Joffre, C; Kaoma, T; Kaphan, E; Kluza, J; Larrue, C; Marine, JC; Mazzotti, C; Mouchel, PL; Nicot, N; Picard, M; Poillet-Perez, L; Polley, N; Rambow, F; Récher, C; Sabatier, M; Sahal, A; Saland, E; Sarry, JE; Stuani, L; Su, X; Tamburini, J; Tiong, IS; Tosolini, M; Vergez, F; Wang, Y; Wei, AH1
Chen, L; Chen, P; Hou, D; Huang, H; Li, D; Lin, X; Wang, B; Wang, X; You, R; Zhang, B; Zheng, X1
Cao, Y; Han, C; Li, L; Shen, J; Yu, X1
Castillo, TBD; Delgado, A; Duan, Y; Enjeti, AK; Garbayo Guijarro, B; Gimenez Conca, A; Girshova, L; Guvenc, B; Hsiao, HH; Lee, JH; Llamas, C; Martelli, MP; Miyamoto, T; Olivera, LJE; Sanford, D; Tomuleasa, C1
Aldrich, J; Alvarado, Y; Borthakur, G; Daver, N; DiNardo, C; Garcia-Manero, G; Kadia, T; Ohanian, M; Patel, K; Pemmaraju, N; Ravandi, F; Senapati, J; Shoukier, M; Wang, X1
Bhojwani, D; Brown, P; Burke, MJ; Chang, BH; Chi, YY; Colace, SI; Florendo, E; Gossai, N; Heimbruch, K; Hermiston, ML; Heym, K; Hutchinson, RJ; Huynh, VT; Kaplan, JA; Malvar, J; Mody, R; O'Brien, TA; Place, AE; Pommert, L; Pulakanti, K; Rao, S; Schafer, ES; Shaw, PH; Sposto, R; Stelloh, C; Wayne, A; Ziegler, DS1
Cheng, S; Ding, X; Gao, L; Hu, S; Hu, Y; Li, B; Li, Z; Ling, J; Lu, J; Lu, Q; Pan, J; Ribeiro, RC; Wang, J; Wang, Y; Xiao, P; Zheng, J1
Chen, CY; Cui, ZL; Fu, Y; Gao, ZX; Liu, F; Ma, S; Zhang, L; Zhou, MR1
Bai, J; Pei, Z; Song, Q; Wang, H; Wang, J; Wu, H; Zhang, B1
Lancet, J; Ravandi, F1
Babushok, DV; Carulli, A; Frey, NV; Freyer, CW; Gill, SI; Graveno, ME; Hexner, EO; Loren, AW; Luger, SM; Mangan, BL; Martin, ME; McCurdy, SR; Nietupski, R; Perl, AE; Porter, DL; Pratz, KW1
Chen, J; Fang, Q; Gong, B; Gong, X; Gu, R; Jin, J; Li, Y; Lin, D; Liu, B; Liu, K; Liu, Y; Mi, Y; Qiu, S; Song, Z; Wang, J; Wang, Y; Wei, H; Wei, S; Yang, M; Zhang, G; Zhang, J; Zhou, C1
Bagnoli, JW; Enard, W; Hellmann, I; Herold, T; Jayavelu, AK; Jeremias, I; Jurinovic, V; Mann, M; Richter, D; Valtierra-Gutiérrez, IA; Vick, B; Zeller, C1
Bai, H; Duan, J; Fu, W; Li, Y; Liang, X; Peng, Y; Yu, W; Zhang, Q1
Bui, CN; Conca, AG; Del Castillo, TB; Delgado, A; Duan, Y; Enjeti, AK; Girshova, L; Guijarro, BG; Guvenc, B; Hsiao, HH; Ito, T; Lee, JH; Llamas, C; Martelli, MP; Olivera, LJE; Sanford, D; Tomuleasa, C1
Bewersdorf, JP; Goshua, G; Huntington, SF; Patel, KK; Podoltsev, NA; Shallis, RM; Zeidan, AM1
Feng, Y; Guryanova, OA; Kaur, P; Shabashvili, DE; Venugopal, K1
Anderson, R; Ghiraldeli, L; Pardee, TS; Pladna, K1
Guo, H; Lu, W; Shi, J; Zhang, Y; Zhang, Z; Zhu, J1
Gao, W; Hu, J; Jiang, J; Wan, M; Wang, L1
Anderson, R; Bhave, RR; Chou, JW; Dralle, S; Ellis, LR; Howard, DS; Isom, S; Lyerly, S; Manuel, M; Miller, LD; Pardee, TS; Pladna, KM; Powell, BL; Schramm, NJ1
Ali, S; Burnett, AK; Cahalin, P; Clark, RE; Hills, RK; Kjeldsen, L; Russell, NH; Thomas, IF1
Ando, J; Delgado, A; Duan, Y; Eto, T; Garbayo Guijarro, B; Imada, K; Ishikawa, Y; Ito, T; Katsuoka, Y; Kawakami, Y; Kiyoi, H; Kizaki, M; Komeno, T; Kondo, T; Llamas, C; Miyamoto, T; Mori, A; Morita, T; Morita, Y; Nakayama, M; Satake, A; Takezako, N; Taneike, I; Uoshima, N; Watanabe, J; Yamamoto, K; Yoshida, C1
Huang, ZP; Liu, M; Zhang, JZ2
DU, CK; Lu, Y1
Huleihel, M; Kapelushnik, J; Khaleel, B; Lunenfeld, E2
Beckermann, BM; Catalani, O; Cavenagh, J; Deeren, D; Fenaux, P; Genevray, M; Girshova, L; Jamois, C; Konopleva, MY; Krauter, J; Martinelli, G; Montesinos, P; Muehlbauer, S; Mundt, K; Ott, M; Ottmann, O; Petrini, M; Pigneux, A; Rambaldi, A; Recher, C; Rodriguez-Veiga, R; Röllig, C; Schäfer, JA; Taussig, D; Vey, N; Wei, AH; Yoon, SS1
Borthakur, G; Brandt, M; Daver, N; DiNardo, CD; Garcia-Manero, G; Jabbour, E; Jain, N; Kadia, TM; Kantarjian, H; Kim, K; Konopleva, M; Loghavi, S; Pemmaraju, N; Pierce, S; Rausch, CR; Ravandi, F; Sasaki, K; Short, NJ; Tang, G; Yilmaz, M1
Chen, R; Li, L; Li, X; Sun, J; Xie, M; Xie, W; Yang, X; Ye, X; Zheng, X; Zhu, J; Zhu, L; Zhu, M1
Ahmed, SO; Aljurf, M; Alotaibi, S; Mohty, M; Niederwieser, D; Sanz, J1
Azarnoush, S; Dhunputh, C; Ducassou, S; Leverger, G; Merched, M; Pasquet, M; Petit, A; Strullu, M1
Faderl, S; Goldberg, SL; Lancet, JE; Lin, TL; Newell, LF; Ryan, RJ; Uy, GL; Wieduwilt, MJ1
Gong, P; Jing, Y; Wang, Y; Waxman, S; Yin, C; Zhang, J; Zhang, Z; Zhao, L1
Benjamin, K; Bui, CN; Devine, J; DiNardo, CD; Fiedler, W; Fracchiolla, N; Ivanov, V; Jonas, BA; Kamalakar, R; Kim, I; Mendes, W; Montesinos, P; Novak, J; Ofran, Y; Panayiotidis, P; Pejsa, V; Potluri, J; Pratz, KW; Recher, C; Schuh, AC; Stevens, D; Turgut, M; Wei, AH; Wei, X; Yamamoto, K; Yeh, SP1
Al-Antary, ET; Edwards, H; Ge, Y; Gupte, A; Ravindranath, Y; Taub, JW1
Ben Khoud, M; Brinster, C; Figeac, M; Leprêtre, F; Mopin, A; Quesnel, B; Sebda, S; Villenet, C1
Babushok, DV; Bruno, XJ; Carroll, MP; Frey, NV; Gill, SI; Hexner, EO; Hwang, WT; Loren, AW; Luger, SM; Maillard, IP; Margolis, D; Martin, ME; Matthews, AH; McCurdy, SR; Paralkar, VR; Perl, AE; Porter, DL; Pratz, KW; Stadtmauer, EA1
Liu, Z; Xiang, B; Zeng, Q1
Arrigo, G; Audisio, E; Cerrano, M; D'Ardìa, S; Frairia, C; Freilone, R; Giai, V; Secreto, C; Urbino, I1
Adeoti, M; Alvarado, Y; Andreeff, M; Borthakur, G; Bravo, GM; Daver, N; DiNardo, CD; Garcia-Manero, G; Issa, G; Jabbour, E; Jain, N; Kadia, T; Kantarjian, HM; Konopleva, MY; Kornblau, S; Lachowiez, CA; Loghavi, S; Maiti, A; Masarova, L; Pemmaraju, N; Ravandi, F; Sasaki, K; Short, NJ; Takahashi, K; Wang, SA; Xiao, L; Yilmaz, M1
Barthélémy, A; Berthon, C; Cheok, M; Farfariello, V; Guillemette, A; Idziorek, T; Jouy, N; Labiad, O; Laguillaumie, MO; Lemonnier, L; Lewuillon, C; Peyrouze, P; Quesnel, B; Shaik, FA; Tarhan, MC; Titah, S; Touil, Y1
Elonen, E; Huhtala, H; Itälä-Remes, M; Jantunen, E; Kairisto, V; Kauppila, M; Koistinen, P; Koivunen, E; Kolonen, A; Kuittinen, T; Nousiainen, T; Ollikainen, H; Pelliniemi, TT; Penttilä, K; Porkka, K; Pyörälä, M; Räty, R; Rauhala, A; Rimpiläinen, J; Rintala, H; Ruutu, T; Säily, M; Sankelo, M; Silvennoinen, R; Sinisalo, M; Volin, L1
Fang, QY; Gong, BF; Gong, XY; Li, Y; Lin, D; Liu, BC; Liu, KQ; Liu, YT; Mi, YC; Qiu, SW; Wang, JX; Wang, Y; Wei, H; Wei, SN; Zhang, CX; Zhang, GJ; Zhou, CL1
Fang, YJ; Huang, J; Li, HM; Sun, XY; Wang, YP; Xue, Y1
Li, LC; Wang, JD; Yang, SS; Zeng, QF; Zheng, F; Zhou, Z1
Bay, JO; Béné, MC; Bertrand, P; Bonmati, C; Carré, M; Darrouzain, F; Gallego-Hernanz, MP; Gyan, E; Hérault, O; Hunault, M; Lioure, B; Peterlin, P; Picou, F; Pigneux, A; Récher, C; Ternant, D; Vallet, N1
Andreeff, M; Bhalla, KN; Borthakur, G; Daver, NG; DiNardo, CD; Ferrajoli, A; Garcia-Manero, G; Issa, GC; Jabbour, E; Jain, N; Kadia, TM; Kanagal-Shamanna, R; Kantarjian, HM; Konopleva, MY; Malla, R; Montalban-Bravo, G; Ohanian, M; Pemmaraju, N; Popat, UR; Quagliato, K; Rausch, CR; Ravandi, F; Reville, PK; Sasaki, K; Short, NJ; Takahashi, K; Wang, X1
Jiang, Y; Ye, Z1
Byrne, J; Chromik, J; de Botton, S; DiNardo, CD; Döhner, H; Doronin, V; Fathi, AT; Frankfurt, O; Hasan, M; Kim, HJ; Koprivnikar, J; Laille, E; Larson, RA; Martin-Regueira, P; Montesinos, P; Ommen, H; Papayannidis, C; Pigneux, A; Salamero, O; Schuh, AC; Semochkin, S; Thol, F; Thomas, X; Vidriales, MB; Vyas, P; Wei, AH; Yu, X1
Bhojwani, D; Burke, MJ; Chao, K; Colace, SI; Doan, A; Gossai, NP; Guinipero, T; Hilsenbeck, SG; Hinson, A; Jo, E; Kaplan, JA; Otterson, D; Pommert, L; Schafer, ES; Stevens, AM; Wayne, AS1
Amit, O; Apel, A; Bar-On, Y; Frisch, A; Moshe, Y; Nachmias, B; Ofran, Y; Raanani, P; Ram, R; Shargian, L; Shimony, S; Vainstein, V; Wolach, O; Yeshurun, M1
Al-Kali, A; Alkhateeb, H; Begna, KH; Chen, D; Elliott, MA; Gangat, N; Hogan, WJ; Hook, CC; Ketterling, RP; Litzow, MR; Mangaonkar, A; Pardanani, A; Patnaik, MS; Shah, M; Tefferi, A; Viswanatha, D1
Adès, L; Ayaka, P; Benaksas, C; Berrou, J; Boissel, N; Braun, T; Chat, L; Chauvel, C; Clappier, E; Dal Bello, R; Di Feo, G; Dombret, H; Duchmann, M; Fenouille, N; Itzykson, R; Joudinaud, R; Kim, R; Ling, F; Pacchiardi, K; Pardieu, B; Pasanisi, J; Preudhomme, C; Puissant, A; Raffoux, E; Sodaro, G; Vaganay, C; Vasseur, L1
Ai, J; Arnall, J; Avalos, BR; Boselli, D; Chen, T; Chiad, Z; Chojecki, AL; Copelan, EA; Cruz, A; DiSogra, KY; Grunwald, MR; Karabinos, A; Knight, TG; Patel, R; Ragon, BK; Sanikommu, SR; Shah, NA; Symanowski, J; Verbyla, A1
Chan, O; Deutsch, Y; Eatrides, J; Jain, AG; Komrokji, R; Kuykendall, A; Lancet, J; Lee, D; Padron, E; Sallman, D; Sweet, K; Talati, C1
Aumann, S; Frisch, A; Gatt, ME; Gross Even-Zohar, N; Gural, A; Leiba, R; Nachmias, B; Ofran, Y; Shaulov, A; Vainstein, V; Zimran, E; Zohar, Y; Zuckerman, T1
Balasubramanian, P; Das, S; Ijee, S; Kumar, S; Stallon Illangeswaran, RS; Velayudhan, SR1
Alsdorf, WH; Bokemeyer, C; Brauneck, F; Fiedler, W; Ghandili, S; Karagiannis, P; Klingler, F; Modemann, F; Wolschke, C1
Batinic, D; Batinic, J; Bedalov, A; Dembitz, V; Lalic, H; Smoljo, T; Tomic, B; Visnjic, D1
Dai, Z; Fan, S; Hu, H; Jiao, Q; Li, J; Liang, Y; Lv, XB; Sun, J; Tang, X; Wang, M; Yan, J; Yu, B; Yuan, X; Zhang, C; Zhang, F; Zhang, Z1
Chen, Y; Fang, Q; Hu, T; Ni, M; Pan, C; Wang, J; Wang, W; Zhang, S; Zhang, T1
Ball, BJ; Koller, PB; Pullarkat, V1
Cao, Y; Chen, J; Chen, L; Li, X; Ren, J; Wu, J; Zhang, Y1
Biemond, BJ; Boersma, RS; Chalandon, Y; de Weerdt, O; Deeren, D; Efthymiou, A; Fehr, M; Graux, C; Gregor, M; Heim, D; Janssen, JJWM; Jongen-Lavrencic, M; Klein, SK; Legdeur, MCJC; Löwenberg, B; Manz, M; Ossenkoppele, GJ; Pabst, T; Sinnige, HAM; Spertini, O; Stüssi, G; Tick, LW; van der Poel, MWM; van Norden, Y; van Obbergh, F; van Sluis, G; Westerweel, PE1
Srinivasan, S1
Anzai, N; Arai, Y; Atsuta, Y; Fukuda, T; Hiramoto, N; Kanda, J; Kawamura, K; Kimura, T; Konuma, T; Mizuno, S; Murata, M; Nakamae, H; Onizuka, M; Ota, S; Ozawa, Y; Sawa, M; Shimomura, Y; Takahashi, S; Takami, A; Tanaka, M; Yanada, M1
Abernathy, KM; Byrne, M; Chen, H; Gatwood, KS; Perciavalle, MA; Zakhari, MM1
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Bandini, G; Barbui, T; Bassan, R; Battista, R; Ciolli, S; D'Emilio, E; Leoni, F; Rosti, G; Todeschini, G; Zuffa, E1
Fukawa, H; Harano, H; Hashimoto, Y; Kanamori, H; Kodama, F; Maruta, A; Matsuzaki, M; Miyashita, H; Murata, T; Noguchi, T1
Biliczki, F; Bozóky, G1
Hiddemann, W1
Mansberg, R; Rowlings, PA; Rozenberg, MC; Yip, MY1
Amadori, S; Arcese, W; Isacchi, G; Mandelli, F; Meloni, G; Monarca, B; Petti, MC; Testi, AM1
Bettelheim, P; Dudczak, R; Hinterberger, W; Kyrle, PA; Lechner, K; Niessner, H; Pabinger, I; Schwarzinger, I; Speiser, W1
Dhanapongsathorn, V; Intragumtornchai, T; Laongsiri, P; Mahasandana, S; Rajatapiti, B; Wanakrairoj, P1
Boesen, AM; Brincker, H; Christensen, BE; Drivsholm, A; Ellegaard, J; Hansen, OP; Hippe, E; Jans, H; Jensen, KB; Pedersen-Bjergaard, J1
Creutzig, U; Ritter, I; Schellong, G1
Preĭsler, KhD; Raza, A1
Bleher, E; Civin, CI; Ducore, J; Inoue, S; Krischer, J; Pitel, P; Ravindranath, Y; Sexauer, C; Steuber, CP; Vega, R1
Potter, MN; Rogers, S; Slade, RR1
Akazawa, K; Asano, Y; Harada, M; Morioka, E; Niho, Y; Okamura, S; Shibuya, T1
Nagata, K; Nara, N; Suzuki, T; Tohda, S1
Ciolli, S; Leoni, F; Morfini, M; Patriarchi, S; Rossi Ferrini, P1
Lishner, M; McCulloch, EA; Minden, MD; Wang, C1
Berglund, G; Gustafsson, G; Jonmundsson, G; Lie, SO; Siimes, M; Yssing, M1
Krulder, JW; Vlasveld, LT; Willemze, R1
Hoshino, K; Kageyama, S; Katayama, N; Kobayashi, T; Komada, F; Minami, N; Nishii, K; Nishikawa, M; Shirakawa, S; Tsukada, T1
Chen, PM; Chuang, MW; Fan, S; Hsieh, RK; Liu, CJ; Liu, JH; Tzeng, CH1
Aul, C; Büchner, T; Heinecke, A; Hiddemann, W; Löffler, H; Ludwig, W; Maschmeyer, G; Nowrousian, M1
Arlin, Z; Cartwright, K; Case, DC; Desai, P; Feldman, E; Moore, J; Saletan, S; Sia, L; Wiernik, P1
Rolston, KV1
Camitta, BM; Clavell, LA; Garcea, MJ; Gelber, RD; Grier, HE; Link, MP; Weinstein, HJ1
Ausserer, B; Fink, FM; Gadner, H; Grümayer, ER; Kardos, G; Mutz, I; Revesz, T; Schuler, D; Urban, C1
Broccia, G; Caronia, F; Di Raimondo, F; Fioritoni, G; Ladogana, S; Leone, G; Liso, V; Musso, M; Neri, A; Petti, MC1
Ehninger, G; Fackler-Schwalbe, E; Freund, M; Heil, G; Hoelzer, D; Kurrle, E; Link, H; Löffler, B; Lösch, A; Mitrou, PS1
Blasius, S; Büchner, T; Hiddemann, W; Koch, P; Kuse, R; Ludwig, WD; Maschmeyer, G; Sodomann, H; Thiel, E; Tirier, C1
Bennett, JM; Cassileth, PA; Harrington, DP; Hines, JD; Lynch, E; Mazza, JJ; McGlave, P; O'Connell, MJ; Oken, MM1
Austein, J; Diedrich, H; Fackler-Schwalbe, E; Freund, M; Henke, M; Hoffmann, R; Link, H; Schlimok, G; Wandt, H; Wilke, H1
Appelt, M; Büchner, T; Eichelbaum, M; Grille, W; Hiddemann, W; Hossfeld, DK; Koslowski, B; Kraft, J; Kuse, R; Quabeck, K1
Aul, HC; Donhuijsen-Ant, R; Grüneisen, T; Hiddemann, W; Köppler, H; Lathan, B; Ludwig, WD; Maschmeyer, G; Reichle, A; Urbanitz, D1
Estey, E; Heinemann, V; Keating, M; Plunkett, W1
Abels, J; de Gast, GC; Dekker, AW; Löwenberg, B; Sonneveld, P; van der Lelie, J; van Putten, WL; Verdonck, LF; Willemze, R; Zwaan, FE1
Beran, M; Deisseroth, A; Estey, EH; Gutterman, JU; Kantarjian, HM; Keating, MJ; McCredie, KB1
Bodey, GP; Deisseroth, AB; Dixon, D; Estey, EH; Freireich, EJ; Kantarjian, HM; Keating, MJ; Kurzrock, R; McCredie, K; Talpaz, M1
Ben-Ishay, Z; Prindull, G; Sharon, S; Yankelev, S1
Bayle, C; el Zimeity, M; Sabbour, MS1
Broustet, A; Corront, B; Gastaut, JA; Maraninchi, D; Marit, G; Michallet, M; Montastruc, M; Reiffers, J; Sotto, JJ; Stoppa, AM1
Degos, L2
Burke, PJ; Geller, RB; Karp, JE; Santos, GW; Saral, R1
Burke, PJ; Donehower, RC; Karp, JE2
Jacobs, P; Martell, RW; Wilson, EL1
Benjamin, DR; Bernstein, ID; Buckley, JD; Feig, SA; Kim, TH; Lampkin, BC; Ruymann, FB; Smithson, WA; Srivastava, AK; Woods, WG1
Chan, TK; Chiu, E; Liang, R; Todd, D1
Kamiya, K; Nakamura, T; Uchida, M; Ueda, T1
Brizzi, MF; Clark, SC; Lista, P; Pegoraro, L; Resegotti, L; Rossi, M1
Bosly, A; Chatelain, C; Delannoy, A; Doyen, C; Ferrant, A; Ghilain, JM; Martiat, P; Michaux, JL; Sokal, G1
Buscarini, L; Cavanna, L; Civardi, G; Di Stasi, M; Fornari, F; Moretto, M; Sbolli, G1
Butturini, A; Gale, RP; Perocco, P; Santucci, MA; Tura, S1
Chiba, P; Eher, R; Knapp, W; Köller, U; Kraupp, M; Salamon, J; Szekeres, T; Tihan, T1
Boyer, D; Gordon, R; Inoue, S1
Andreeff, M; Tafuri, A1
Gore, M; Helenglass, G; Milan, S; Parikh, P; Pinkerton, R; Powles, R; Rose, M; Smith, C; Talbot, D; Treleaven, J1
Daeschner, CW; Heath, DV; Lockhart, LH; McCombs, JL; Rouse, BM1
Imai, Y; Maruyama, Y; Nagata, K; Nara, N; Suzuki, T; Tohda, S; Tomiyama, J; Yamashita, Y1
Yao, EG; Zhang, RX1
Barcos, M; Bennett, J; Browman, G; Day, R; Kukla, C; Lykins, J; Preisler, HD; Raza, A; White, M; Yasin, Z1
Bartolucci, A; Cohen, HJ; Raney, MR; Stein, RS; Vogler, WR; Winton, EF1
Billström, R; Carneskog, J; Grimfors, G; Hellström, E; Kimby, E; Lindemalm, C; Oberg, G; Robèrt, KH; Samuelsson, J; Winqvist, I1
Aul, CH; Büchner, T; Heinecke, A; Hiddemann, W; Maschmeyer, G; Schleyer, E; Uhrmeister, C1
Itou, S; Koyama, S; Shibata, A1
Brière, J; Desablens, B; Ghandour, C; Harousseau, JL; Milpied, N1
Arning, M; Aul, C; Gehrt, A; Hadding, U; Runde, V; Schneider, W1
Bordessoule, D; Casassus, P; Castaigne, S; Degos, L; Desablens, B; Henry-Amar, M; Le Prisé, PY; Tertian, G; Tilly, H1
Dahl, GV; Johnson, FL; Kalwinsky, DK; Look, AT; Mason, C; Mirro, J; Murphy, SB; Pui, CH; Ruggiero, M; Schell, M1
Arentsen-Honders, MW; Colly, LP; Peters, WG; Willemze, R1
Estey, EH; Freireich, EJ; Keating, MJ; McCredie, KB; Plunkett, W1
Hassan, HT; Rees, JK1
Grant, S; Howe, C; Kuczynski, T1
Smith, JG; Smith, MA; Taylor, PC1
Büchner, T; Heinecke, A; Hiddemann, W; Martin, WR; Sauerland, CM1
Bär, BM; de Pauw, BE; de Witte, T; Haanen, C1
Björkholm, M; Björnsdottir, J; Grimfors, G; Stenke, L1
ten Kate, RW; Wijermans, PW1
Kramer, B; Reich, WK; Scheulen, ME; Skorzec, M1
Briere, J; Casassus, P; Desablens, B; Gandhour, C; Harousseau, JL; Ifrah, N; Le Prise, PY; Milpied, N1
Dekker, AW; Nieuwenhuis, HK; Verdonck, LF; Witteveen, EO1
Gattringer, C; Konwalinka, G; Linkesch, W; Thaler, J1
Amess, J; Davis, CL; Lim, J; Lister, TA; Rohatiner, AZ1
Aul, C; Schneider, W1
Büchner, T; Essink, ME; Hiddemann, W; van de Loo, J; von Eiff, M1
Havemann, K; Koeppler, H; Pflueger, KH; Weide, R; Wolf, M1
Domae, N; Fukushima, T; Kagawa, D; Kamiya, K; Nakamura, T; Tsutani, H; Uchida, M; Ueda, T; Yoshida, W1
Cotes, PM; Hellebostad, M; Marstrander, J; Refsum, HE; Slørdahl, SH1
Chen, TP; Lin, SF; Liu, HW1
Cassileth, PA1
Chapuis, B; Grob, JP; Helg, C; Pugin, P1
Evans, C; Rosenfeld, CS; Shadduck, RK; Winkelstein, A; Zeigler, ZR1
Cosson, A; Estienne, MH; Fenaux, P; Lai, JL; Lepelley, P; Preudhomme, C; Zandecki, M1
Carcassonne, Y; Gastaut, JA; Launay, MC; Lejeune, C; Maraninchi, D; Richard, B; Sainty, D; Sebahoun, G; Tubiana, N1
Han, P; Kueh, YK; Suri, R; Tan, YO1
De Fabritiis, P; Mandelli, F; Meloni, G; Petti, MC1
Advani, SH; Banavali, SD; Charak, BS; Gopal, R; Kurkure, PA; Nadkarni, KS; Nair, CN; Pai, SK; Pai, VR; Saikia, TK1
Bauters, F; Fenaux, P; Gardin, C; Lai, JL1
Nooter, K; Sonneveld, P1
Dekker, AW; Nieuwenhuis, HK; Verdonck, LF1
Boughton, BJ; Franklin, I; Goldstone, AH; Gribben, JG; Leyland, MM; Linch, DC; McMillan, AK; Milligan, DW; Patterson, KG; Richards, JD1
Hölzel, D; Nüssler, V; Pelka-Fleischer, R; Sauer, H; Wilmanns, W1
De Pauw, B; De Witte, T; Haanen, C; Muus, P1
Capizzi, RL; Contento, MM; Craig, JB; Do, KA; Gregory, BW; Kute, TE; Lyerly, ES; Powell, BL1
Fountzilas, G; Inoue, S; Ohnuma, T1
Saito, Y; Uzuka, Y3
Bian, SG; Hao, YS; Wang, ZC1
Bishop, JF; Cobcroft, R; Dodds, A; Joshua, D; Kronenberg, H; Lowenthal, RM; Ma, D; Matthews, JP; Todd, D; Whiteside, MG1
Cooper, JT; Friedman, DJ; Halvorson, RD; Hurt, MA; Petr, FC1
Heimpel, H; Hoelzer, D; Kurrle, E1
Nieuwenhuis, HK; Sixma, JJ1
Bhalla, K; Gleyzer, M; Grant, S1
McCulloch, EA; Wang, C1
Burnison, M; Champlin, R; Decker, R; Gale, RP; Greenberg, P; Ho, W; Holly, FE; Winston, D1
Gyger, M; Momparler, LF; Momparler, RL; Onetto, N1
Catovsky, D; Chessells, JM; Galton, DA; Goldman, JM; Hann, IM; Hoffbrand, AV; Marcus, RE; Newland, AC; Prentice, HG; Stevens, RF1
Gray, R; Hayhoe, FG; Rees, JK1
Baehner, RL; Buckley, JD; Chard, RL; Hammond, GD; Lampkin, BC; Nesbit, ME; Woods, WG1
Archimbaud, E; Fiere, D; Sebban, C1
Boschetti, C; Cofrancesco, E; Cortellaro, M; Moreo, G; Pogliani, E; Salvatore, M1
Brodzki, LM; Gepner-Woźniewska, M; Pawelski, S3
Girasoli, M; Leone, G; Liene, DR; Marra, R; Pagano, L; Storti, S1
Hołowiecki, J; Mandecki, M; Wnuk-Wojnar, AM; Wojnar, J1
Meyers, PA; Redner, A; Steinherz, PG; Tan, CT1
Bender-Götze, C; Haas, RJ; Holler, E; Kolb, HJ; Thierfelder, S; Wilmanns, W1
Bernasconi, C; Bernasconi, P; Bonfichi, M; Castagnola, C; Colombo, A1
Bentley, DP; Campbell, IA; Green, AR; Poynton, C1
Huijgens, PC; Langenhuijsen, MM; Nauta, JJ; Ossenkoppele, GJ; Wijermans, PW1
Aso, T; Hino, H; Hirota, Y; Kondou, S; Makuuchi, M; Matsumoto, I; Nishiura, S; Takata, K1
Büchner, T; Essink, M; Hiddemann, W; Huhn, D; Jung, M; Koppensteiner, R; Marosi, L; Martin, T; Minar, E; Siegert, W1
Bardy, P; Branford, AL; Dart, GD; Dyson, PG; Haylock, DN; Ho, JQ; Horvath, N; Roberts, MM; Thorp, D; To, LB1
Bernard, P; Boiron, JM; Marit, G; Reiffers, J; Rice, A; Vezon, G1
Jehn, U; Zittoun, R1
Cepelák, V; Koza, V; Slechtová, J; Svojgrová, M1
Carella, AM; D'Amico, T; Damasio, E; Gaozza, E; Giordano, D; Nati, S; Piatti, G; Pungolino, E; Spriano, M1
Bernabei, PA; Dal Pozzo, O; Rossi Ferrini, P; Saccardi, R; Santini, S; Santini, V1
Tanaka, M; Yoshida, S1
Frenkel', MA; Perilov, AA; Volkova, MA1
Cullen, J; Freeman, AI; Hicks, RA; Jackson, MA; Sotiropoulos, SV; Woods, GM1
Kyo, T; Maehama, S1
Ohshima, T1
Huijgens, PC; Langenhuijsen, MM; Ossenkoppele, GJ; van Geel, BM; Wijermans, PW1
Avalos, M; Brivet, F; Dommergues, JP; Léonard, C; Miélot, F; Mirica, C; Tchernia, G; Tertian, G1
Wahlin, A1
Ihle, H; Ihle, R; Matthes, H1
Bernhart, M; Fiedler, E; Kasparu, H; Krieger, O; Lutz, D; Weber, E1
Gao, RL; Jin, JM; Ma, FS1
Dufour, P; Facon, T; Guy, H; Harousseau, JL; Hurteloup, P; Ifrah, N; Milpied, N; Reiffers, J; Rigal-Huguet, F1
Bearden, JD; Capizzi, RL; Jackson, DV; Lyerly, ES; Morgan, TM; Muss, HB; Powell, BL; Richards, F; Rosenbaum, DL; White, DR1
Amadori, S; Avvisati, G; Covelli, A; De Laurenzi, A; Leone, G; Leoni, P; Liso, V; Mandelli, F; Neri, A; Petti, MC1
Champlin, RE; Gajewski, JL; Golde, DW1
Abels, J; Bury, J; Fière, D; Haanen, C; Hayat, M; Jehn, U; Löwenberg, B; Peetermans, M; Willemze, R; Zittoun, R1
Carr, T; Chang, J; Coutinho, LH; Deakin, DP; Dexter, TM; Morgenstern, GR; Scarffe, JH; Testa, NG1
Omura, G; Raney, M; Velez-Garcia, E; Vogler, WR1
Aegerter, P; Gorin, NC; Gratwohl, A; Hayat, M; Hermans, J; Stijnen, T; Stryckmans, P; Suciu, S; Zittoun, R; Zwaan, FE1
Azarnia, N; Benger, A; Browman, G; Chervenick, P; D'Arrigo, P; Doeblin, T; Goldberg, J; Preisler, H; Raza, A; Syracuse, K1
Amadori, S; Ceci, A; Comelli, A; Defazio, D; Madon, E; Mandelli, F; Masera, G; Nespoli, L; Paolucci, G; Zanesco, L1
Broccia, G; Carotenuto, M; De Rosa, F; Di Marco, P; Di Raimondo, F; Fioritoni, G; Leone, G; Mandelli, F; Petti, MC; Vegna, ML1
Alessandrino, EP; Bernasconi, C; Bernasconi, P; Bonfichi, M; Caldera, D; Lazzarino, M; Merante, S; Morra, E1
Dicke, KA; Spinolo, JA1
Amadori, S; De Fabritiis, P; Mandelli, F; Meloni, G; Petti, MC; Pulsoni, A; Sandrelli, A1
Goldstone, AH; Gribben, JG; Linch, DC; MacMillan, AK; Richards, JD1
Bernasconi, C1
Forgeson, G; Gore, M; Goss, G; Lakhani, A; Maitland, J; Milan, S; Nandi, A; Perren, T; Powles, R; Treleaven, J1
Morgan, HJ; Schreiner, RD1
Cannistra, SA; Griffin, JD; Groshek, P1
Düllmann, J; Gerhartz, H; Illinger, H; Keilhauer, R; König, H; Linkesch, W; Michlmayr, G; Moldrzyk, D1
Aul, C; Balleisen, L; Donhuijsen-Ant, R; Grüneisen, T; Hiddemann, W; Hoffmann, R; Köppler, H; Lathan, B; Ludwig, WD; Maschmeyer, G1
Dohy, H; Kyo, T3
Bustelo, P; Freigeiro, D; Jiménez, E; Kohan, R; Kvicala, R; Pavlovsky, S; Richard, L; Sackmann Muriel, F; Santarelli, MT; Scaglione, C1
Drozdova, TS; Maiakova, SA; Makhonova, LA1
Burke, PJ; Geller, RB; Karp, JE; Vaughan, WP1
Braine, HG; Burke, PJ; Fox, MG; Geller, RB; Hall, KL; Humphrey, RL; Karp, JE; Morrell, L; Tucker, RW; Zahurak, M1
Bernstein, ID; Buckley, JD; Feig, SA; Hammond, GD; Kersey, JH; Kim, T; Lampkin, BC; Nesbit, ME; Piomelli, S1
Bogdanić, V; Hauptman, E; Jaksić, B; Kovacević, J; Labar, B; Minigo, H; Mrsić, M; Nemet, D; Pavletić, Z; Sertić, D1
Pretnar, J1
Gastineau, DA; Gerstner, JB; Goldberg, RM; Gundlach, WJ; Kardinal, CG; Letendre, L; Mailliard, JA; Niedringhaus, RD; Pierre, RV; Therneau, TM1
Estey, E; Heinemann, V; Keating, MJ; Plunkett, W1
Ciolli, S; Leoni, F; Rossi Ferrini, P1
Andreeff, M; Berman, E; Clarkson, BD; Gabrilove, J; Gee, TS; Gulati, S; Kempin, SJ; Raymond, V; Wiernik, PH; Young, CW1
Carella, AM; Cerri, R; Giordano, D; Nati, S; Piatti, G; Pungolino, E; Risso, M1
Boughton, BJ; Donohue, SM1
Gahrton, G; Liliemark, J; Paul, C; Peterson, C; Tidefelt, U1
Dybedal, I; Lamvik, J1
Iavorkovskiĭ, LI; Klutse, GK; Shvidel', LM; Zile, MA1
Abakumov, EM; Faĭnshteĭn, FE; Isaev, VG; Kucher, RA; Shakhbaian, GP1
Bennett, JM; Cassileth, P; Ebrahim, K; Kahn, SB; Knospe, WH; O'Connell, MJ1
Kodera, Y; Minami, S; Morishima, Y; Morishita, Y; Nagai, T; Ohno, R; Saito, H; Tanimoto, M; Yokomaku, S1
Fukutani, H; Hirano, A; Horikoshi, N; Inoue, K; Itami, S; Mizunuma, N; Mukaiyama, T; Ogawa, M; Tabata, M1
Hassan, FM; Pesce, AJ; Pruemer, JM; Warner, A; Wermeling, JR1
Hino, K; Nakamaki, T; Sakashita, A; Sano, M; Suzuki, K; Tomoyasu, S; Tsuruoka, N1
Akagi, K; Asou, N; Goto, J; Hamasaki, N; Hidaka, M; Kawano, F; Kurisaki, H; Sawatari, T; Suzushima, H; Takatsuki, K1
Alvarez, A; del Potro, E; Díaz Mediavilla, J; Díaz Morfa, M; Guerra, JL; Krsnik, I; Llorente, L; López, JC; Martínez, R; Villegas, A1
Brinch, L; Evensen, SA; Wisløff, F1
Ozaki, S; Ryo, R; Saigo, K; Tatsumi, E; Ueda, K; Yamaguchi, N1
Hoffman, MS; Turnquist, D1
Castaman, G; Castronovo, S; Cortesi, S; Dini, E; Quaglio, R; Rodeghiero, F; Soffiati, G1
Bagot, M; Cordonnier, C; Jais, JP; Kuentz, M; Landais, P; Oksenhendler, E; Roujeau, JC; Vernant, JP1
Kano, Y; Kitagawa, S; Miura, Y; Muto, Y; Sakamoto, S; Sasaki, R; Suda, K; Takaku, F; Tsuboyama, A; Yoshida, M1
Hayashi, K; Ito, T; Kamiya, O; Kinoshita, T; Nagata, K; Ohara, K; Ono, Y; Saito, M; Sugiura, I; Yamamoto, K1
Damon, LE; Linker, CA; Mass, R1
Kelleher, CA; McCulloch, EA; Minkin, S; Miyauchi, J; Wang, C1
Deng, CG; Hu, HZ; Li, SQ; Liu, MY; Wang, YJ; Wu, JX; Yao, QX; Zhang, YL; Zhu, S1
Champlin, RE; Gajewski, JL; Gekelman, L; Hirji, KF; Ho, WG; Jacobs, AD; Nimer, SD1
Ito, T; Komatu, M; Saito, Y; Takahashi, H; Uzuka, Y1
Curtis, JE; Lishner, M; McCulloch, EA; Minkin, S1
Castaman, G; Rodeghiero, F; Ruggeri, M1
Caro, J; Erslev, AJ; Piroso, E1
Catovsky, D; Galton, DA; Goldman, JM; Hegde, U; Marcus, RE; Newland, AC; Slocombe, G1
Gore, ME; Lwin, KY; Powles, RL; Sloane, JP; Smith, JF1
Aul, HC; Büchner, T; Donhuijsen-Ant, R; Hiddemann, W; Kreutzmann, H; Lengfelder, E; Ludwig, WD1
Copplestone, JA; Hamblin, TJ; Mufti, GJ; Oscier, DG; Worsley, A1
Bayle, J; Cassuto, JP; Dujardin, P; Fuzibet, JG; Gratecos, N; Pesce, A; Raynaud, S2
Gray, RG; Hayhoe, FG; Rees, JK; Swirsky, D1
Burke, PJ; Dole, GB; Donehower, RC; Enterline, JP; Fox, MG; Karp, JE1
Amadori, S; Mandelli, F; Meloni, G; Miniero, R; Papa, G; Petti, MC1
Andreeff, M; Arlin, ZA; Berman, E; Gaynor, J; Gee, T; Kempin, SJ; Mertelsmann, R; Miller, W; Nahmias, N; Reich, L1
Dua, H; Kochupillai, V; Kumar, L1
de Arriba, G; Hernando, L; Oliva, H; Ordi, J; Thomson, M1
Burns, CP; Lazarus, HM; Vogler, WR; Winton, EF1
Graves, T; Hooks, MA1
Anderson, K; Cuttner, J; DuPre, E; Holland, JF; Preisler, HD; Rai, K; Yates, J1
Annaloro, C; Cortelezzi, A; Cortellaro, M; Della Volpe, A; Lambertenghi-Deliliers, G; Maiolo, AT; Mozzana, R; Pogliani, E; Polli, EE; Pozzoli, E1
Mandelli, F; Petti, MC1
Arlin, ZA; Case, DC; Periman, PO; Ritch, PS; Todd, MB; Weitberg, AB; Wiernik, PH1
Andreeff, M; Berman, E; Gabrilove, J; Gee, T; Gulati, S; Heller, G; Kempin, SJ; Kolitz, J; Raymond, V; Young, CW1
Gerhartz, HH; Kolb, HJ; Mittermüller, J; Wilmanns, W2
Li, CW; Li, YS; Zhang, TD1
Holt, PJ; Lucas, GS; Shall, L; Whittaker, JA1
Gustavsson, A; Kjellén, E; Olofsson, T; Pero, RW1
Capizzi, RL; Cooper, MR; Lyerly, ES; Powell, BL1
Einhorn, S; Gahrton, G; Hellström, E; Robèrt, KH1
Ross, DW3
Bennett, TE; Chaplinski, TJ1
Oberg, G; Venge, P1
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Bordessoule, D; Brière, J; Castaigne, S; Colombat, P; Donadio, D; Drony, S; Guy, H; Sigaux, F; Solal Celigny, P; Tilly, H1
Morley, AA; Wan, JH1
Finch, LR; Jamieson, GP; Sawyer, WH; Snook, M; Taupin, J; Wiley, JS1
Desforges, J; Johnson, H; Smith, TJ1
Cheng, GY; Curtis, JE; McCulloch, EA; Tritchler, D1
Champlin, RE; Elashoff, R; Feig, SA; Gale, RP; Ho, WG; Lenarsky, C; Mitsuyasu, R; Selch, M; Winston, D; Zighelboim, J1
Brittinger, G; Heidemann, H; Lunscken, C; Meusers, P; Uppenkamp, M; Zou, P1
Anders, C; Miller, AA; Nowrousian, MR; Ohl, S; Schmidt, CG; Seeber, S1
Brudler, O; Heil, G; Kurrle, E1
Dickerhoff, R; Haas, RJ1
Breithaupt, H; Pralle, H1
Pees, HW; Radtke, H1
Gassmann, W; Löffler, H; Schmitz, N1
Oken, MM; Perri, RT; Weisdorf, DJ1
Jehn, U; Löwenberg, B1
Grier, HE; Weinstein, HJ1
Amare, M; Balcerzak, SP; Chen, T; Costanzi, JJ; Gutterman, JU; Hewlett, JS1
Bodey, GP; Freireich, EJ; Hurtubise, M; Keating, MJ; Leavens, M; Maor, M; McCredie, KB; Smith, TL; Stewart, DJ1
Curtis, JE; Messner, HA; Minden, MM1
Champlin, R; Feig, SA; Gale, RP; Ho, W; Jacobs, A; Lenarsky, C; Selch, M1
Bodenstein, H; Eisert, R; Freund, M; Poliwoda, H1
Büchner, T; Heinecke, A; Hiddemann, W; Koch, P; Maschmeier, G; Pielken, HJ; Urbanitz, D; van de Loo, J; Wendt, F1
Jehn, U; Löwenberg, B; Zittoun, R1
Aul, HC; Büchner, T; Fischer, J; Hiddemann, W; Kuse, R; Ludwig, WD; Rühl, H; Urbanitz, D; Vaupel, HA; Zeile, G1
Höcker, P1
Francis, S; Gokhale, U; Kochupillai, V; Kumar, S; Mehra, NK; Nanu, A; Sharma, S; Takkar, D; Verma, IC1
Berney, JJ; Francis, GE; Guimaraes, JE; Wing, MA1
Barnett, MJ; Butler, MG; Ganesan, TS; Lister, TA; Richards, MA; Rohatiner, AZ; Slevin, ML; Smith, BF; Waxman, JH1
Kufe, DW; Spriggs, DR1
Ishikura, H; Izumi, Y; Mochizuki, T; Okazaki, T; Sawada, H; Tashima, M; Uchino, H1
Shan, YD1
Carmel, R; Coltman, CA1
Mann, JR1
Bailey, CC; Brown, MJ; Geary, CG; Israëls, MC; Weatherall, DJ; Whittaker, JA1
Canellos, GP; Whang-Peng, J1
Keane, WM; Khaleeli, M; Lee, GR1
Barkhan, P; Black, PJ; Rose, MS1
Demeulenaere, L; Hamers, J; Van Hove, W1
Beard, ME; Fairley, GH1
Grignani, F; Martelli, M; Tonato, M2
Chan, YK; Vogler, WR1
McElwain, TJ; Smith, IE1
Bodey, GP; Burgess, MA; Freireich, EJ; Gehan, E; Gutterman, JU; Hersh, EM; Mavligit, G; McCredie, KB; Reed, R; Rodriguez, V; Smith, T1
Danieli, G1
Atkinson, K; Clink, HM; Kay, HE; McElwain, TJ; Powles, R; Wells, DG1
Abeloff, MD; Anderson, PN; Bias, WB; Borgaonkar, DS; Braine, HG; Burke, PJ; Davis, TE; Humphrey, RL; Mullins, GM; Santos, GW; Sensenbrenner, LL; Slavin, RE; Tutschka, PJ1
Rosner, F; Seligman, BR1
Jaenicke, L; Sauer, H; Wilmanns, W; Wilms, K1
Almici, C; Inzoli, MR1
Speck, B; Zwaan, FE1
Bolognesi, DP; Green, RW; Metzgar, RS; Miller, DS; Mohanakumar, T1
Rebuck, JW; Van Slyck, EJ1
Alexander, P; Bateman, CJ; Beard, ME; Crowther, D; Fairley, GH; Lister, TA; McElwain, TJ; Pike, M; Powles, RL; Russell, J; Whitehouse, JM; Wrigley, PF1
Bryan, JH; Johnson, GE; Leventhal, BG1
Zubrod, CG3
Lampkin, B; Mauer, AM; McWilliams, NB1
Komp, DM1
Anderson, JC; Henderson, WG; Palmer, CA; Rogers, RT1
Ruffner, BW1
Ganeshaguru, K; Hoffbrand, AV; Tattersall, MH1
Hustinx, TW; Rutten, FJ; Scheres, JM; Wagener, DJ1
Bourdarias, H; Caruel, N; Najman, A; Singer, B1
Bateman, CJ; Beard, ME; Crowther, D; Malpas, JS; Whitehouse, JM1
Labitan, A; Momparler, RL; Rossi, M1
Gunz, FW; Levi, JA; Vincent, PC2
Giralt, M; Raichs, A; Torres, A1
Cheung, WH; Rai, KR; Sawitsky, A1
Lampkin, BC; Mauer, AM; McWilliams, NB2
Fülle, HH; Pribilla, W1
Frei, E1
Montuori, R; Quattrin, N1
Amar, M; Boivin, P; Hakim, J; Kahn, A1
Moloney, WC; Rosenthal, DS; Wiernik, PH1
Praga, C1
Lee, SL; Parise, F; Rosner, F; Seligman, BR1
Abu-Zahra, H; Clarysse, A; Cowan, DH; McCulloch, EA; Senn, JS1
Böhnel, J; Höcker, P; Stacher, A1
Bauters, F; Goudemand, M; Lerche, B; Samsoen, J1
Wilmanns, W; Wilms, K1
Bateman, DN; Rose, MS1
Bornstein, RS; Kennedy, BJ; Nesbit, M1
Fennelly, JJ; Gorman, A; O'Connell, LG1
Armentrout, SA; Burns, CP; Stjernholm, RL1
Bastrup-Madsen, P; Jensen, KB; Petersen, HS; Thorling, K1
Abu-Zahra, H; Bergsagel, DE; Clarysse, A; Cowan, DH; Hasselback, R1
Kjeldsberg, CR; Ward, HP1
Salvati, A1
Au-Yong, R; Collins, P; Young, JA1
Granatir, RG; Moquin, RB; Perlin, E; Roche, J1
Baker, DH; Berdon, WE; Renert, WA1
Basch, A; Dreyfus, B; Gluckman, E; Varet, B1
Brodin, A; Gold, J; Steinberg, D1
Duttera, MJ; Geelhoed, GW; Graff, KS; Henderson, ES1
Bateman, CJ; Beard, ME; Crowther, D; Fairley, GH; Gauci, CL; Malpas, JS; Powles, RL; Scott, RB; Wrigley, PF1
Ishii, M; Nishi, H; Sakurai, M1
Flieder, J; Gehanno, P; Lallemant, Y1
Domańska, B; Lawkowicz, W; Polubiec, A1
Infelise, V; Paolino, W; Resegotti, L; Rossi, M1
Janele, J; Rosa, L1
Gemon, MF; Jacquillat, C; Weil, M1
Nagao, T; Tashiro, Y; Toyosaka, H; Tsukimoto, I1
Abbrederis, K; Braunsteiner, H; Huber, H; Michlmayr, G; Schmalzl, F1
Dublin, P; Leikin, S; Movassaghi, N1
Bull, JM; Carbone, PP; Duttera, MJ; Henderson, E; Northup, J; Stashick, ED1
Bloomfield, CD; Theologides, A1
Buchanan, JG; Casey, TP; Davison, JG; Grigor, RR; Matthews, JR1
Mathe, G; Pouillart, P; Schwarzenberg, L1
Delamore, IW; Freeman, CB; Geary, CG; Harris, R; Leyland, MJ; MaCiver, JE1
Jungi, WF1
Gjemdal, T; Stavem, P1
Frei, E; Goldin, A; Schabel, FM1
Ernst, P; Faille, A; Killmann, SA1
Hamblin, TJ; Jones, JV1
Clarkson, B; Erichson, R; Finch, S; Flannery, J; Grann, V1
Alberto, P; Brunner, KW; Martz, G; Nagel, G; Obrecht, JP; Senn, HJ1
Albrecht, M; Fülle, HH1
Delamore, IW; Mir, MA2
Bickers, JN; Coltman, CA; Freireich, EJ; Gehan, EA; Hewlett, JS; Stuckey, WJ; Van Slyck, EJ; Wilson, HE1
Bodey, GP; Bonnet, JD; Coltman, CA; Freireich, EJ; Gehan, EA; Haut, AB; Hewlett, JS; McCredit, KB; Saiki, JH; Wilson, HE1
Fleming, I; Jackson, R; Johnson, W; Mason, C; Simone, J; Walters, T1
Burchenal, JH; Clarkson, BD; Dowling, MD; Gee, TS1
Bodey, GP; Frei, E; Freireich, E; Ho, DH1
Bleihöfer, B; Englebert, B; Gerhartz, H; Paulisch, R; Schneider, J1
Burchenal, JH; Cole, MT; Dowling, MD1
Gahrton, G; Jonasson, J; Lindsten, J; Simonsson-Lindemalm, C; Zech, L1
Friend, JH; Giles, C; Richardson, SG1
Seip, M1
Ernst, P1
Brun, B; Dreyfus, B; Gluckman, E; Reyes, F; Rochant, H1
Drings, P; Fritsch, H; Moskwa, G; Sefrin, R; von Kaick, G1
Ruzicka, F; Weigerstorfer, B1
Brincker, H; Hansen, PB1
Asseburg, U; Barlogie, B; Büchner, T; Göhde, W; Hiddemann, W; Kamanabroo, D1
Abbrederis, K; Michlmayr, G; Schmalzl, F1
Buckley, J; Metcalf, D; Moore, MA; Spitzer, G; Williams, N1
Sacks, PV; Tavassoli, M1
Sakurai, M; Sandberg, AA1
Momparler, RL1
Amar, M; Bernard, JF; Boivin, P; Garbaz, M; Hakim, J; Kahn, A1
Burgess, MA; Freireich, EJ; Gutterman, JU; Hersh, EM; Matthews, A; Mavligit, GM; McCredie, KB1
Böhnel, J; Gingold, N; Hermansky, F; Pawlowski, M; Stacher, A1
Bax, I; Greenberg, P; Mara, B; Schrier, S1
Engstedt, L; Franzén, S; Gahrton, G; Gullbring, B; Höglund, S; Holm, G; Killander, A; Killander, D; Lockner, D; Mellstedt, H; Palmblad, J; Reizenstein, P; Skarberg, KO; Swedberg, B; Udén, AM1
Bayrd, ED; Kyle, RA; Pierre, RV1
Keating, MJ; Penington, DG1
Aye, MT; McCulloch, EA; Niho, Y; Till, JE1
Bergna, L; Eppinger-Helft, M; Hidalgo, G; Macchi, A; Pavlovsky, A; Pavlovsky, S; Sackmann Muriel, F; Suarez, A; Vilaseca, G1
Brott, W; Green, DC; Treasure, RL; Zumbro, GL1
Asseburg, U; Barlogie, B; Büchner, T; Kamanabroo, D1
Baroncelli, PG; Cordero di Montezemolo, L; Madon, E; Roberi, PL; Sacerdote, A1
Burchenal, JH; Clarkson, BD; Cunningham, B; Dowling, MD; Gee, TS; Haghbin, M; Tan, CT1
Amiel, JL; Cattan, A; De Vassal, F; Hayat, M; Jasmin, C; Mathé, G; Pouillart, P; Rosenfeld, C; Schneider, M; Schwarzenberg, L; Weiner, R1
Sakai, Y; Sakano, T1
Armentrout, SA; Burns, CP1
Bricteux, N1
Ono, R1
Sakano, T1
Bertino, JR; DeConti, RC; Hubbard, S; Marsh, JC; Mitchell, MS; Skeel, RT1
Cooper, LE; Groth, DP; Vogler, WR1
Bernard, J; Jacquillat, C; Weil, M2
Pöttgen, W1
Delalieux, G; Manaster, J; Stryckmans, P1
Brilliant, MD1
Powles, R2
Buckner, CD; Clift, RA; Fass, L; Fefer, A; Glucksberg, H; Mickelson, EM; Neiman, P; Storb, R; Thomas, ED1
Hansen, NE; Karle, H1
Schrier, SL; Silvergleid, AJ1
Bauters, F; Caulier, MT; Goudemand, M; Mouton, J; Plouvier, B1
Hacker, B; Hall, TC; Kessel, D; Nahas, A1
Baccarani, M; Lauria, F; Ricci, P; Santucci, MA; Tura, S1
Carnelli, V; Masera, G; Uderzo, C1
Bernard, J; Faille, A; Najean, Y1
Bernard, J; Blom, J; Boiron, M; Cuttner, J; Ellison, RR; Forcier, RJ; Gussoff, B; Haurani, F; Hayes, DM; Holland, JF; Hutchison, JL; Jacquillat, C; Karanas, A; Kyle, R; Leone, LA; Moon, JH; Rosner, F; Sawitsky, A; Silver, RT; Spurr, CL; Weil, M1
Jacquillat, C1
Bernard, J; Boiron, M; Jacquillat, C; Weil, M1
Dano, K; Nissen, NI1
Perry, S; Skipper, HE1
Bateman, CJ; Crowther, D; Fairley, GH; Malpas, JS; Scott, RB; Vartan, CP; Whitehouse, JM1
Clarkson, BD; Fried, J1
Fairley, GH2
Frei, E; Goldin, A; Henderson, ES; Holland, JF; Newman, JW; Sandberg, JS1
Dean, HM; Post, RM1
Cline, MJ1
Gerhartz, H1
Bodey, GP; Freireich, EJ; Harris, JE; Hart, JS1
Holland, JF1
Lee, SL; Rosner, F1
Crosby, WH1
Hall, TC; Kessel, D; Rosenthal, D1
Hall, TC; Roberts, D; Rosenthal, D1
Clarkson, BD; Gee, TS; Yu, KP1
Lampkin, BC; Mauer, AM; Nagao, T2
Begemann, H; Kreiter, H; Rastetter, J1
Bodey, GP; DeJongh, D; Freireich, EJ; Isassi, A1
Aoki, Y; Moore, GE1
Groth, DP; Horwitz, S; Vogler, WR1
Aguercif, M; Dubois-Ferrière, H; Hazeghi, P; Rudhardt, M1
Pratt, CB; Wang, JJ1
Brodie, GN; Penny, R1
Finklestein, JZ; Freedman, MH; Gilchrist, GS; Hammond, GD; Higgins, GR; Hyman, CB; Karon, MR; Shore, NA; Williams, KO1
Benesová, E; Friedmann, B; Hermanský, F1
Amano, I; Higo, O; Horiuchi, A; Morita, K; Oshima, T1
White, LP1
Ridell, B; Weinfeld, A; Westin, J1
Canova, R; Casalino, C; Fischioni, P; Maroncelli, P1
Bryon, PA; Dechavanne, M; Fiere, D; Guyon, JM; Kahi, S; Revol, L1
Barry, A; Delage, JM1
McLean, FW; Noyes, WD; Pawliger, DF1
Bertino, JR; Capizzi, RL; Creasey, WA; Handschumacher, RE; Olayon, C; Peterson, RG; Skeel, RT; Zanes, R1
Curci, G; De Pasquale, A; Montero, C; Piccinini, L; Quaglino, D1
Frei, E; Freireich, EJ; George, SL; Hart, JS; Trujillo, JM1
Crowther, D1
Cuesta, MB; Gabriel, FD; Kozinn, PJ; Rosener, F; Taschdjian, C1
Colebatch, JH; Ekert, H; Lay, HN1
Foadi, M; Shaw, MT1
Cork, A; Drewinko, B; Freireich, EJ; Hart, JS; Trujillo, JM1
Burke, PJ; Steuart, CD1
Gerron, GG; Howard, CH; Rudman, D; Vogler, WR1
Baroncelli, PG; Madon, E; Roberi, PL; Sacerdote, A1
Das, L; Dohlwitz, A; Hall, TC; Jaffe, N; Moloney, WC; Traggis, DG1
Henderson, ES; Leventhal, BG1
Burke, PJ; Owens, AH1
Cornwell, GG; McIntyre, OR; Mills, RC1
Bodey, GP; Freireich, EJ; Hersh, EM; McCredie, KB; Whitecar, JP1
Baguley, BC; Falkenhaug, EM1
Benirschke, K; Forcier, RJ; Maurer, LH; McIntyre, OR1
Cohen, SL; Dodsworth, H; Whitelaw, AG1
Hirano, M; Koie, K; Morita, A; Sako, F; Uetani, T1
Braunsteiner, H; Schmalzl, F1
Bagshawe, KD1
Buchanan, JG1
Hall, TC1
Wilmanns, W1
Hitzig, WH; Plüss, HJ1
Bodey, GP; Frei, E; Freireich, E; Hart, J; Whitecar, J1
Blom, J; Burningham, R; Cuttner, J; Falkson, G; Glidewell, O; Holland, JF; Levy, RN; Moon, JH; Onuma, T; Rosner, F; Silver, RT1

Reviews

327 review(s) available for cytarabine and Acute Myelogenous Leukemia

ArticleYear
SOHO State of the Art Updates and Next Questions:Harnessing Apoptosis in AML.
    Clinical lymphoma, myeloma & leukemia, 2022, Volume: 22, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Humans; Leukemia, Myeloid, Acute; Protein Kinase Inhibitors

2022
The cure of leukemia through the optimist's prism.
    Cancer, 2022, 01-15, Volume: 128, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Fusion Proteins, bcr-abl; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Protein Kinase Inhibitors

2022
Is there an optimal adjunct therapy to traditional cytotoxic induction?
    Best practice & research. Clinical haematology, 2021, Volume: 34, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Remission Induction

2021
Is the current consolidation regimen for AML evidence-based?
    Best practice & research. Clinical haematology, 2021, Volume: 34, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Middle Aged; Remission Induction

2021
Venetoclax combination therapy in acute myeloid leukemia and myelodysplastic syndromes.
    Current opinion in hematology, 2022, 03-01, Volume: 29, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Sulfonamides

2022
Venetoclax combined with hypomethylating agents or low-dose cytarabine as induction chemotherapy for patients with untreated acute myeloid leukemia ineligible for intensive chemotherapy: a systematic review and meta-analysis.
    Clinical and experimental medicine, 2023, Volume: 23, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute

2023
Diagnosis and treatment of therapy-related acute myeloid leukemia.
    Critical reviews in oncology/hematology, 2022, Volume: 171

    Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Mutation; Prognosis

2022
Targeting AraC-Resistant Acute Myeloid Leukemia by Dual Inhibition of CDK9 and Bcl-2: A Systematic Review and Meta-Analysis.
    Journal of healthcare engineering, 2022, Volume: 2022

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cyclin-Dependent Kinase 9; Cytarabine; Humans; Leukemia, Myeloid, Acute; Protein Kinase Inhibitors

2022
Combination strategies to promote sensitivity to cytarabine-induced replication stress in acute myeloid leukemia with and without DNMT3A mutations.
    Experimental hematology, 2022, Volume: 110

    Topics: Cytarabine; DNA Repair; Humans; Leukemia, Myeloid, Acute; Mutation; Nucleosides

2022
[Research Advance of Gene Mutation and Targeted Drug Therapy in Childhood Acute Myeloid Leukemia --Review].
    Zhongguo shi yan xue ye xue za zhi, 2022, Volume: 30, Issue:2

    Topics: Adult; Child; Cytarabine; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Mutation; Myeloproliferative Disorders; Nuclear Proteins; Nucleophosmin; Prognosis

2022
Current Status of CPX-351 Therapy in Acute Myeloid Leukemia and Myelodysplastic Syndrome.
    Clinical lymphoma, myeloma & leukemia, 2022, Volume: 22, Issue:8

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes

2022
The paradox of Myeloid Leukemia associated with Down syndrome.
    Biochemical pharmacology, 2022, Volume: 201

    Topics: Child; Cytarabine; Down Syndrome; GATA1 Transcription Factor; Humans; Leukemia, Myeloid, Acute; Leukemoid Reaction

2022
Gilteritinib in Isolated Breast Relapse of FLT3 Positive Acute Myeloid Leukemia: A Case Report and Review of Literature.
    Acta haematologica, 2022, Volume: 145, Issue:5

    Topics: Aged; Aniline Compounds; Azacitidine; Cytarabine; Daunorubicin; Female; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Mutation; Pyrazines; Recurrence

2022
Venetoclax in combination with nucleoside analogs in acute myelogenous leukemia.
    Current opinion in oncology, 2022, 09-01, Volume: 34, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Humans; Leukemia, Myeloid, Acute; Nucleosides; Sulfonamides

2022
Reported Pericardial Toxicities Associated with Acute Myelogenous Leukemia Treatments: A Pharmacovigilance Analysis of the FDA Adverse Reporting Database.
    Current problems in cardiology, 2022, Volume: 47, Issue:11

    Topics: Adolescent; Adult; Aminopyridines; Anthracyclines; Azacitidine; Bridged Bicyclo Compounds, Heterocyclic; Cladribine; Cytarabine; Decitabine; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Pericarditis; Pharmacovigilance; Sulfonamides; Triazines; United States; United States Food and Drug Administration

2022
Central Nervous System Prophylaxis and Treatment in Acute Leukemias.
    Current treatment options in oncology, 2022, Volume: 23, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Central Nervous System; Central Nervous System Neoplasms; Cytarabine; Humans; Leukemia, Myeloid, Acute; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma

2022
Consolidation chemotherapy in AML: Are we playing with a full deck of cards?
    Best practice & research. Clinical haematology, 2022, Volume: 35, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Consolidation Chemotherapy; Cytarabine; Humans; Leukemia, Myeloid, Acute; Remission Induction; Stem Cell Transplantation

2022
The increasingly blurred line between induction, consolidation and maintenance in acute myeloid leukaemia.
    British journal of haematology, 2023, Volume: 200, Issue:5

    Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Remission Induction; Transplantation, Homologous; Young Adult

2023
Real-world experience with CPX-351 in high-risk acute myeloid leukemia.
    Critical reviews in oncology/hematology, 2023, Volume: 185

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Liposomes

2023
The core concepts of core binding factor acute myeloid leukemia: Current considerations for prognosis and treatment.
    Blood reviews, 2023, Volume: 62

    Topics: Core Binding Factors; Cytarabine; Humans; Leukemia, Myeloid, Acute; Prognosis; Recurrence

2023
Safety and efficacy of FLAG-Ida-based therapy combined with venetoclax for the treatment for newly diagnosed and relapsed/refractory patients with AML - A systematic review.
    Leukemia research, 2023, Volume: 133

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Humans; Idarubicin; Leukemia, Myeloid, Acute

2023
Comparative Efficacy of Venetoclax-Based Combination Therapies and Other Therapies in Treatment-Naive Patients With Acute Myeloid Leukemia Ineligible for Intensive Chemotherapy: A Network Meta-Analysis.
    Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 2023, Volume: 26, Issue:12

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bayes Theorem; Cytarabine; Humans; Leukemia, Myeloid, Acute; Network Meta-Analysis; Treatment Outcome

2023
Acute myeloid leukemia: from NGS, through scRNA-seq, to CAR-T. dissect cancer heterogeneity and tailor the treatment.
    Journal of experimental & clinical cancer research : CR, 2023, Oct-06, Volume: 42, Issue:1

    Topics: Cytarabine; Humans; Leukemia, Myeloid, Acute; Receptors, Chimeric Antigen; Recurrence; Single-Cell Gene Expression Analysis

2023
Cladribine, cytarabine, and filgrastim based regimen in relapsed or refractory acute myeloid leukemia: A systematic review and meta-analysis.
    Medicine, 2023, Nov-03, Volume: 102, Issue:44

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cytarabine; Filgrastim; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Remission Induction

2023
[Research Advances on Combination Strategies of Demethylating Agents for Elderly Acute Myeloid Leukemia--Review].
    Zhongguo shi yan xue ye xue za zhi, 2019, Volume: 27, Issue:4

    Topics: Aclarubicin; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Isocitrate Dehydrogenase; Leukemia, Myeloid, Acute

2019
CPX-351 (vyxeos) in AML.
    Leukemia & lymphoma, 2020, Volume: 61, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Middle Aged; Multicenter Studies as Topic; Myelodysplastic Syndromes; Randomized Controlled Trials as Topic

2020
Leukemic Vasculitis: Case Report and Review of the Literature.
    The American Journal of dermatopathology, 2019, Volume: 41, Issue:11

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Bone Marrow Transplantation; Colitis, Ulcerative; Cytarabine; Diagnosis, Differential; Erythema; Female; Humans; Idarubicin; Immunohistochemistry; Leg Dermatoses; Leukemia, Myeloid, Acute; Leukemic Infiltration; Mesalamine; Skin Neoplasms; Transplantation Conditioning; Treatment Outcome; Vasculitis

2019
The role of cladribine in acute myeloid leukemia: an old drug up to new tricks.
    Leukemia & lymphoma, 2020, Volume: 61, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cytarabine; Humans; Leukemia, Myeloid, Acute; Pharmaceutical Preparations; Remission Induction

2020
Post-remission therapy in acute myeloid leukemia: Are we ready for an individualized approach?
    Best practice & research. Clinical haematology, 2019, Volume: 32, Issue:4

    Topics: Allografts; Cytarabine; Daunorubicin; Gemtuzumab; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Precision Medicine; Remission Induction

2019
Single-agent and combination biologics in acute myeloid leukemia.
    Hematology. American Society of Hematology. Education Program, 2019, 12-06, Volume: 2019, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Gemtuzumab; Humans; Isocitrate Dehydrogenase; Leukemia, Myeloid, Acute; Neoplasm Proteins; Sulfonamides; Survival Rate

2019
How to address second and therapy-related acute myelogenous leukaemia.
    British journal of haematology, 2020, Volume: 188, Issue:1

    Topics: Age Factors; Allografts; Antibodies, Bispecific; Antineoplastic Agents, Immunological; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Immunotherapy, Adoptive; Leukemia, Myeloid, Acute; Remission Induction; Stem Cell Transplantation

2020
Recent drug approvals for newly diagnosed acute myeloid leukemia: gifts or a Trojan horse?
    Leukemia, 2020, Volume: 34, Issue:3

    Topics: Antineoplastic Agents; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Daunorubicin; Drug Approval; Gemtuzumab; Glycine; Humans; Leukemia, Myeloid, Acute; Phenylurea Compounds; Pyridines; Randomized Controlled Trials as Topic; Staurosporine; Sulfonamides; United States; United States Food and Drug Administration

2020
Long-term follow-up of Cladribine, high-dose Cytarabine, and Idarubicin as salvage treatment for relapsed acute myeloid leukemia and literature review.
    European journal of haematology, 2020, Volume: 104, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Cladribine; Cytarabine; Female; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Recurrence; Salvage Therapy; Survival Analysis; Treatment Outcome

2020
A User's Guide to Novel Therapies for Acute Myeloid Leukemia.
    Clinical lymphoma, myeloma & leukemia, 2020, Volume: 20, Issue:5

    Topics: Allografts; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Leukemia, Myeloid, Acute; Stem Cell Transplantation; United States; United States Food and Drug Administration

2020
Advances in non-intensive chemotherapy treatment options for adults diagnosed with acute myeloid leukemia.
    Leukemia research, 2020, Volume: 91

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Decitabine; Gemtuzumab; Glycine; Humans; Leukemia, Myeloid, Acute; Male; Molecular Targeted Therapy; Phenylurea Compounds; Precision Medicine; Pyridines; Recurrence; Remission Induction; Staurosporine; Sulfonamides

2020
AML: New Drugs but New Challenges.
    Clinical lymphoma, myeloma & leukemia, 2020, Volume: 20, Issue:6

    Topics: Aniline Compounds; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Cytarabine; Daunorubicin; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Phenylurea Compounds; Pyrazines

2020
EMA Review of Daunorubicin and Cytarabine Encapsulated in Liposomes (Vyxeos, CPX-351) for the Treatment of Adults with Newly Diagnosed, Therapy-Related Acute Myeloid Leukemia or Acute Myeloid Leukemia with Myelodysplasia-Related Changes.
    The oncologist, 2020, Volume: 25, Issue:9

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Ireland; Leukemia, Myeloid, Acute; Liposomes

2020
The efficacy and safety of daunorubicin versus idarubicin combined with cytarabine for induction therapy in acute myeloid leukemia: A meta-analysis of randomized clinical trials.
    Medicine, 2020, Jun-12, Volume: 99, Issue:24

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Randomized Controlled Trials as Topic; Recurrence; Remission Induction; Safety; Survival Analysis; Topoisomerase II Inhibitors; Treatment Outcome; United States; Young Adult

2020
Combination treatment with CPX-351 and midostaurin in patients with secondary acute myeloid leukaemia that are FLT3 mutated: three cases and review of literature.
    British journal of haematology, 2020, Volume: 190, Issue:3

    Topics: Aged; Allografts; Anemia, Refractory, with Excess of Blasts; Aniline Compounds; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Breast Neoplasms; Bridged Bicyclo Compounds, Heterocyclic; Clinical Trials, Phase III as Topic; Cytarabine; Daunorubicin; Fatal Outcome; Female; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Liposomes; Male; Middle Aged; Myelodysplastic Syndromes; Neoplasm, Residual; Neoplasms, Radiation-Induced; Oncogene Proteins, Fusion; Peripheral Blood Stem Cell Transplantation; Point Mutation; Protein Kinase Inhibitors; Pyrazines; Remission Induction; Salvage Therapy; Staurosporine; Sulfonamides

2020
Roles of hsa-miR-12462 and SLC9A1 in acute myeloid leukemia.
    Journal of hematology & oncology, 2020, 07-23, Volume: 13, Issue:1

    Topics: 3' Untranslated Regions; Animals; Cytarabine; Drug Resistance, Neoplasm; Gene Expression Regulation; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Mice; Neoplasm Proteins; RNA, Neoplasm; Sodium-Hydrogen Exchanger 1; Tumor Burden; Tumor Cells, Cultured; U937 Cells; Xenograft Model Antitumor Assays

2020
AML with Myelodysplasia-Related Changes: Development, Challenges, and Treatment Advances.
    Genes, 2020, 07-24, Volume: 11, Issue:8

    Topics: Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Prognosis

2020
Myelodysplastic syndromes: 2021 update on diagnosis, risk stratification and management.
    American journal of hematology, 2020, Volume: 95, Issue:11

    Topics: Administration, Oral; Allografts; Antineoplastic Agents; Cytarabine; Disease-Free Survival; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Risk Assessment; Stem Cell Transplantation; Survival Rate

2020
Acute myeloid leukemia: 2021 update on risk-stratification and management.
    American journal of hematology, 2020, Volume: 95, Issue:11

    Topics: Algorithms; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Daunorubicin; Gemtuzumab; Leukemia, Myeloid, Acute; Randomized Controlled Trials as Topic; Risk Assessment; Staurosporine; Sulfonamides; United States

2020
Diagnosis and Treatment of Patients With Acute Myeloid Leukemia With Myelodysplasia-Related Changes (AML-MRC).
    American journal of clinical pathology, 2020, 11-04, Volume: 154, Issue:6

    Topics: Aged; Aminopyridines; Antineoplastic Agents; Blood Cells; Bone Marrow; Bone Marrow Examination; Chromosome Aberrations; Cytarabine; Cytogenetic Analysis; Daunorubicin; DNA Mutational Analysis; Genetic Predisposition to Disease; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Prognosis; PubMed; Triazines

2020
Midostaurin in acute myeloid leukemia: current evidence and practical considerations in routine clinical use.
    Minerva medica, 2020, Volume: 111, Issue:5

    Topics: Aniline Compounds; Anthracyclines; Antifungal Agents; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Echinocandins; fms-Like Tyrosine Kinase 3; Forecasting; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Maintenance Chemotherapy; Mutation; Mycoses; Protein Kinase Inhibitors; Pyrazines; Randomized Controlled Trials as Topic; Recurrence; Staurosporine; Triazoles

2020
CPX-351 daunorubicin-cytarabine liposome: a novel formulation to treat patients with newly diagnosed secondary acute myeloid leukemia.
    Minerva medica, 2020, Volume: 111, Issue:5

    Topics: Age Factors; Antimetabolites, Antineoplastic; Clinical Trials as Topic; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Liposomes; Middle Aged; Mutation; Myelodysplastic Syndromes

2020
Gemtuzumab ozogamicin in acute myeloid leukemia: past, present and future.
    Minerva medica, 2020, Volume: 111, Issue:5

    Topics: Aged; Animals; Antineoplastic Agents; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Arsenicals; Calicheamicins; Chlorides; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Approval; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; Gemtuzumab; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Mice; Middle Aged; Multicenter Studies as Topic; Recurrence; Sialic Acid Binding Ig-like Lectin 3; Tretinoin

2020
Selection and management of older patients with acute myeloid leukemia treated with glasdegib plus low-dose cytarabine: expert panel review.
    Leukemia & lymphoma, 2020, Volume: 61, Issue:14

    Topics: Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Cytarabine; Humans; Leukemia, Myeloid, Acute; Phenylurea Compounds

2020
New directions for emerging therapies in acute myeloid leukemia: the next chapter.
    Blood cancer journal, 2020, 10-30, Volume: 10, Issue:10

    Topics: Allografts; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Phenylurea Compounds; Quinuclidines; Sulfonamides

2020
Venetoclax as monotherapy and in combination with hypomethylating agents or low dose cytarabine in relapsed and treatment refractory acute myeloid leukemia: a systematic review and meta-analysis.
    Haematologica, 2020, 11-01, Volume: 105, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Humans; Leukemia, Myeloid, Acute; Sulfonamides

2020
Venetoclax-based chemotherapy in acute and chronic myeloid neoplasms: literature survey and practice points.
    Blood cancer journal, 2020, 11-23, Volume: 10, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bridged Bicyclo Compounds, Heterocyclic; Clinical Trials, Phase III as Topic; Cytarabine; Decitabine; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Randomized Controlled Trials as Topic; Sulfonamides

2020
Forsaken Pharmaceutical: Glasdegib in Acute Myeloid Leukemia and Myeloid Diseases.
    Clinical lymphoma, myeloma & leukemia, 2021, Volume: 21, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Benzimidazoles; Cell Line, Tumor; Clinical Trials as Topic; Cytarabine; Drug Approval; Drug Evaluation, Preclinical; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Mice; Phenylurea Compounds; Signal Transduction; Smoothened Receptor; United States

2021
Glasdegib in newly diagnosed acute myeloid leukemia.
    Expert review of anticancer therapy, 2021, Volume: 21, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Cytarabine; Hedgehog Proteins; Humans; Leukemia, Myeloid, Acute; Phenylurea Compounds

2021
Secondary AML Emerging After Therapy with Hypomethylating Agents: Outcomes, Prognostic Factors, and Treatment Options.
    Current hematologic malignancy reports, 2021, Volume: 16, Issue:1

    Topics: Animals; Antineoplastic Agents; Azacitidine; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Daunorubicin; Gemtuzumab; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Molecular Targeted Therapy; Phenylurea Compounds; Prognosis; Sulfonamides

2021
Acute myeloid leukemia: Treatment and research outlook for 2021 and the MD Anderson approach.
    Cancer, 2021, 04-15, Volume: 127, Issue:8

    Topics: Age Factors; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Bridged Bicyclo Compounds, Heterocyclic; Cladribine; Core Binding Factors; Cytarabine; Daunorubicin; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Maintenance Chemotherapy; Mutation; Myelodysplastic Syndromes; Myeloproliferative Disorders; Neoplasm, Residual; Sulfonamides; Survival Rate; Translational Research, Biomedical; Tretinoin; Vidarabine

2021
New Treatment Options for Older Patients with Acute Myeloid Leukemia.
    Current treatment options in oncology, 2021, 03-20, Volume: 22, Issue:5

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Mutation; Patient Selection; Stem Cell Transplantation; Sulfonamides

2021
Which novel agents will have a clinically meaningful impact in AML at diagnosis?
    Best practice & research. Clinical haematology, 2021, Volume: 34, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Humans; Leukemia, Myeloid, Acute

2021
Inhibitors of Chemoresistance Pathways in Combination with Ara-C to Overcome Multidrug Resistance in AML. A Mini Review.
    International journal of molecular sciences, 2021, May-07, Volume: 22, Issue:9

    Topics: Animals; Cell Death; Cytarabine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Leukemia, Myeloid, Acute; Models, Biological

2021
An evaluation of venetoclax in combination with azacitidine, decitabine, or low-dose cytarabine as therapy for acute myeloid leukemia.
    Expert review of hematology, 2021, Volume: 14, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Decitabine; Humans; Leukemia, Myeloid, Acute; Sulfonamides

2021
Core binding factor acute myelogenous leukemia-2021 treatment algorithm.
    Blood cancer journal, 2021, 06-16, Volume: 11, Issue:6

    Topics: Algorithms; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Chromosome Inversion; Chromosomes, Human; Core Binding Factors; Cytarabine; Disease-Free Survival; Humans; Leukemia, Myeloid, Acute; Neoplasm Proteins; Neoplasm, Residual; Translocation, Genetic

2021
3+7 Combined Chemotherapy for Acute Myeloid Leukemia: Is It Time to Say Goodbye?
    Current oncology reports, 2021, 08-04, Volume: 23, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Gemtuzumab; Hematopoietic Stem Cell Transplantation; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Risk Assessment; Staurosporine

2021
Systematic review and meta-analysis of clinical efficacy of drug therapy for acute myelogenous leukemia.
    Annals of palliative medicine, 2021, Volume: 10, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Treatment Outcome

2021
Acute myeloid leukemia with t (3;8) (q26.2;q24), a simple variant of 3q26.2/EVI1 translocation.
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2017, Volume: 58, Issue:4

    Topics: Aged; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 3; Chromosomes, Human, Pair 8; Cytarabine; DNA-Binding Proteins; Humans; Leukemia, Myeloid, Acute; Male; MDS1 and EVI1 Complex Locus Protein; Proto-Oncogenes; Transcription Factors; Translocation, Genetic

2017
Allogeneic hematopoietic cell transplantation in morphologic leukemia-free aplastic state.
    American journal of hematology, 2017, Volume: 92, Issue:9

    Topics: Adult; Aged; Allografts; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cladribine; Combined Modality Therapy; Cytarabine; Etoposide; Female; Filgrastim; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Myelodysplastic Syndromes; Transplantation Conditioning; Treatment Outcome; Young Adult

2017
Acute myeloid leukemia and pregnancy: clinical experience from a single center and a review of the literature.
    BMC cancer, 2017, Jun-23, Volume: 17, Issue:1

    Topics: Abortion, Therapeutic; Adult; Cesarean Section; Child; Cytarabine; Daunorubicin; Female; Fetal Death; Humans; Infant, Newborn; Leukemia, Myeloid, Acute; Pregnancy; Pregnancy Complications, Neoplastic

2017
Cytarabine dose in the consolidation treatment of AML: a systematic review and meta-analysis.
    Blood, 2017, 08-17, Volume: 130, Issue:7

    Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Consolidation Chemotherapy; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Survival Analysis; Young Adult

2017
Cytarabine and daunorubicin for the treatment of acute myeloid leukemia.
    Expert opinion on pharmacotherapy, 2017, Volume: 18, Issue:16

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Recurrence; Remission Induction; Treatment Outcome

2017
Midostaurin, enasidenib, CPX-351, gemtuzumab ozogamicin, and venetoclax bring new hope to AML.
    Blood, 2017, 12-07, Volume: 130, Issue:23

    Topics: Aminoglycosides; Aminopyridines; Antibodies, Monoclonal, Humanized; Bridged Bicyclo Compounds, Heterocyclic; Clinical Trials as Topic; Cytarabine; Daunorubicin; fms-Like Tyrosine Kinase 3; Gemtuzumab; Humans; Isocitrate Dehydrogenase; Leukemia, Myeloid, Acute; Liposomes; Molecular Targeted Therapy; Mutation; Proto-Oncogene Proteins c-bcl-2; Sialic Acid Binding Ig-like Lectin 3; Staurosporine; Sulfonamides; Treatment Outcome; Triazines

2017
Pharmacogenetics of Metabolic Genes of Anthracyclines in Acute Myeloid Leukemia.
    Current drug metabolism, 2018, Volume: 19, Issue:1

    Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Leukemia, Myeloid, Acute; Pharmacogenetics; Polymorphism, Genetic

2018
Do cytogenetics affect the post-remission strategy for older patients with AML in CR1?
    Best practice & research. Clinical haematology, 2017, Volume: 30, Issue:4

    Topics: Aged; Aged, 80 and over; Chromosome Aberrations; Cytarabine; Cytogenetic Analysis; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction

2017
How can one optimize induction therapy in AML?
    Best practice & research. Clinical haematology, 2017, Volume: 30, Issue:4

    Topics: Aminoglycosides; Antibodies, Monoclonal, Humanized; Cytarabine; Daunorubicin; Gemtuzumab; History, 20th Century; History, 21st Century; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute

2017
The role of targeted therapy in the management of patients with AML.
    Hematology. American Society of Hematology. Education Program, 2017, 12-08, Volume: 2017, Issue:1

    Topics: Cytarabine; Daunorubicin; Drug Delivery Systems; Humans; Leukemia, Myeloid, Acute

2017
Midostaurin in Combination With Standard Chemotherapy for Treatment of Newly Diagnosed FMS-Like Tyrosine Kinase 3 (FLT3) Mutation-Positive Acute Myeloid Leukemia.
    The Annals of pharmacotherapy, 2018, Volume: 52, Issue:4

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Mutation; Protein Kinase Inhibitors; Staurosporine; Treatment Outcome

2018
CPX-351: changing the landscape of treatment for patients with secondary acute myeloid leukemia.
    Future oncology (London, England), 2018, Volume: 14, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Carriers; Drug Synergism; Humans; Leukemia, Myeloid, Acute; Liposomes; Prognosis; Survival Rate; Treatment Outcome

2018
Daunorubicin and Cytarabine Liposome in Newly Diagnosed Therapy-Related Acute Myeloid Leukemia (AML) or AML With Myelodysplasia-Related Changes.
    The Annals of pharmacotherapy, 2018, Volume: 52, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Combinations; Drug Interactions; Humans; Leukemia, Myeloid, Acute; Liposomes; Myelodysplastic Syndromes

2018
Salvage regimens using conventional chemotherapy agents for relapsed/refractory adult AML patients: a systematic literature review.
    Annals of hematology, 2018, Volume: 97, Issue:7

    Topics: Adult; Anthracyclines; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Humans; Leukemia, Myeloid, Acute; Patient Selection; Prognosis; Randomized Controlled Trials as Topic; Recurrence; Remission Induction; Retrospective Studies; Salvage Therapy; Survival Analysis; Treatment Outcome

2018
Role of minimal residual disease in the management of acute myeloid leukemia-a case-based discussion.
    Annals of hematology, 2018, Volume: 97, Issue:7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Biopsy; Bone Marrow; Core Binding Factor Alpha 2 Subunit; Cytarabine; Daunorubicin; Disease Management; Female; Flow Cytometry; Humans; Leukemia, Myeloid, Acute; Neoplasm, Residual; Oncogene Proteins, Fusion; Polymerase Chain Reaction; Prognosis; Risk Assessment; RUNX1 Translocation Partner 1 Protein; Sequence Analysis, DNA

2018
How I treat older patients with acute myeloid leukemia.
    Cancer, 2018, 06-15, Volume: 124, Issue:12

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Chromosome Aberrations; Cytarabine; Decitabine; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Hematopoietic Stem Cell Transplantation; Histone Deacetylase Inhibitors; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Prognosis; Remission Induction; Survival Rate; Transplantation, Homologous

2018
Advances in treatment formulations for acute myeloid leukemia.
    Drug discovery today, 2018, Volume: 23, Issue:12

    Topics: Animals; Anthracyclines; Cytarabine; Drug Delivery Systems; Humans; Leukemia, Myeloid, Acute; Pharmaceutical Preparations

2018
Shutting Down Acute Myeloid Leukemia and Myelodysplastic Syndrome with BCL-2 Family Protein Inhibition.
    Current hematologic malignancy reports, 2018, Volume: 13, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Humans; Leukemia, Myeloid, Acute; Mitochondria; Myelodysplastic Syndromes; Neoplastic Stem Cells; Proto-Oncogene Proteins c-bcl-2; Sulfonamides

2018
BCL-2 inhibition in AML: an unexpected bonus?
    Blood, 2018, 09-06, Volume: 132, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Decitabine; Humans; Leukemia, Myeloid, Acute; Proto-Oncogene Proteins c-bcl-2; Sulfonamides

2018
Acute myeloid leukaemia.
    Lancet (London, England), 2018, 08-18, Volume: 392, Issue:10147

    Topics: Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Consolidation Chemotherapy; Cytarabine; Gemtuzumab; Genomics; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Patient Selection; Recurrence; Remission Induction; Risk Assessment; Risk Factors; Staurosporine

2018
[Advances of Targeting Therapy in Acute Myeloid Leukemia--Review].
    Zhongguo shi yan xue ye xue za zhi, 2018, Volume: 26, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Leukemia, Myeloid, Acute; Mutation; Prognosis; Recurrence

2018
Recently approved therapies in acute myeloid leukemia: A complex treatment landscape.
    Leukemia research, 2018, Volume: 73

    Topics: Aminoglycosides; Aminopyridines; Antibodies, Monoclonal, Humanized; Cytarabine; Daunorubicin; Female; Gemtuzumab; Glycine; Humans; Leukemia, Myeloid, Acute; Male; Pyridines; Staurosporine; Triazines

2018
A Bayesian Network Meta-Analysis Comparing the Efficacies of Eleven Novel Therapies with the Common Salvage Regimen for Relapsed or Refractory Acute Myeloid Leukemia.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 49, Issue:4

    Topics: Bayes Theorem; Cytarabine; Disease-Free Survival; Histone Deacetylase Inhibitors; Humans; Leukemia, Myeloid, Acute; Naphthyridines; Neoplasm Recurrence, Local; Odds Ratio; Pyrazoles; Pyrimidines; Remission Induction; Salvage Therapy; Survival Rate; Thiazoles

2018
A comparative evaluation of gemtuzumab ozogamicin + daunorubicin-cytarabine and other treatments for newly diagnosed acute myeloid leukemia.
    Future oncology (London, England), 2019, Volume: 15, Issue:6

    Topics: Adult; Aged; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Female; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Multicenter Studies as Topic; Odds Ratio; Publication Bias; Randomized Controlled Trials as Topic; Recurrence; Remission Induction; Survival Rate; Treatment Outcome

2019
Is the overall survival for older adults with AML finally improving?
    Best practice & research. Clinical haematology, 2018, Volume: 31, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Daunorubicin; Disease-Free Survival; Humans; Leukemia, Myeloid, Acute; Sulfonamides; Survival Rate

2018
Cladribine in the remission induction of adult acute myeloid leukemia: where do we stand?
    Annals of hematology, 2019, Volume: 98, Issue:3

    Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Clinical Trials as Topic; Cytarabine; Dose-Response Relationship, Drug; Drug Interactions; Heart Diseases; Hematologic Diseases; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Liposomes; Meta-Analysis as Topic; Mucositis; Multicenter Studies as Topic; Neoplasms, Second Primary; Remission Induction; Survival Rate; Treatment Outcome

2019
Liposomal Cytarabine-Daunorubicin (CPX-351) Extravasation: Case Report and Literature Review.
    Anticancer research, 2018, Volume: 38, Issue:12

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chest Tubes; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Liposomes; Vascular Access Devices

2018
Daunorubicin/Cytarabine Liposome: A Review in Acute Myeloid Leukaemia.
    Drugs, 2018, Volume: 78, Issue:18

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Approval; Europe; Humans; Leukemia, Myeloid, Acute; Liposomes; Remission Induction; United States

2018
Why are hypomethylating agents or low-dose cytarabine and venetoclax so effective?
    Current opinion in hematology, 2019, Volume: 26, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid, Acute; Neoplastic Stem Cells; Sulfonamides

2019
The leukemia strikes back: a review of pathogenesis and treatment of secondary AML.
    Annals of hematology, 2019, Volume: 98, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Mutation; Tumor Suppressor Protein p53

2019
Glasdegib: First Global Approval.
    Drugs, 2019, Volume: 79, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Cytarabine; Drug Approval; Europe; Hedgehog Proteins; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Phenylurea Compounds; Signal Transduction; United States

2019
Daunorubicin and cytarabine for certain types of poor-prognosis acute myeloid leukemia: a systematic literature review.
    Expert review of clinical pharmacology, 2019, Volume: 12, Issue:3

    Topics: Adult; Animals; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Cytogenetic Analysis; Daunorubicin; Drug Administration Schedule; Humans; Leukemia, Myeloid, Acute; Mutation; Prognosis; Randomized Controlled Trials as Topic

2019
Detection of AML-specific mutations in pediatric patient plasma using extracellular vesicle-derived RNA.
    Annals of hematology, 2019, Volume: 98, Issue:3

    Topics: Adult; Animals; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cytarabine; Disease-Free Survival; Humans; Leukemia, Myeloid, Acute; Nucleophosmin; Remission Induction; Survival Rate

2019
New drugs creating new challenges in acute myeloid leukemia.
    Genes, chromosomes & cancer, 2019, Volume: 58, Issue:12

    Topics: Aminopyridines; Aniline Compounds; Cytarabine; Daunorubicin; fms-Like Tyrosine Kinase 3; Gemtuzumab; Glycine; Humans; Leukemia, Myeloid, Acute; Pyrazines; Pyridines; Staurosporine; Triazines; United States; United States Food and Drug Administration

2019
Excessive Toxicity After Treatment of Congenital Acute Myeloid Leukemia.
    Klinische Padiatrie, 2019, Volume: 231, Issue:6

    Topics: Antimetabolites, Antineoplastic; Cytarabine; Humans; Infant; Leukemia, Myeloid, Acute

2019
Choosing induction chemotherapy in therapy-related acute myeloid leukemia.
    Best practice & research. Clinical haematology, 2019, Volume: 32, Issue:1

    Topics: Cytarabine; Daunorubicin; Enzyme Inhibitors; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Mutation; Neoplasms, Second Primary

2019
[Efficacy and Safety of Decitabine Combined with CAG (Cytarabine, Aclarubicin, G-CSF) for Patients with Intermediate or High Risk Myelodysplastic Syndrome and Acute Myeloid Leukemia: a Meta-Analysis].
    Zhongguo shi yan xue ye xue za zhi, 2019, Volume: 27, Issue:2

    Topics: Aclarubicin; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Decitabine; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes

2019
Immunoliposomes in Acute Myeloid Leukaemia Therapy: An Overview of Possible Targets and Obstacles.
    Current medicinal chemistry, 2019, Volume: 26, Issue:28

    Topics: Animals; Antineoplastic Agents; Cytarabine; Daunorubicin; Drug Carriers; Drug Screening Assays, Antitumor; Humans; Leukemia, Myeloid, Acute; Liposomes; Nanoparticles

2019
Efficacy outcomes in the treatment of older or medically unfit patients with acute myeloid leukaemia: A systematic review and meta-analysis.
    Leukemia research, 2019, Volume: 82

    Topics: Age Factors; Aged; Antimetabolites, Antineoplastic; Azacitidine; Cytarabine; Decitabine; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Survival Analysis; Treatment Outcome

2019
Daunorubicin-cytarabine liposome (CPX-351) in the management of newly diagnosed secondary AML: A new twist on an old cocktail.
    Best practice & research. Clinical haematology, 2019, Volume: 32, Issue:2

    Topics: Aged; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Leukemia, Myeloid, Acute; Male; Survival Rate

2019
Venetoclax-based therapies for acute myeloid leukemia.
    Best practice & research. Clinical haematology, 2019, Volume: 32, Issue:2

    Topics: Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Clinical Trials as Topic; Cytarabine; Daunorubicin; Glycine; Humans; Leukemia, Myeloid, Acute; Phenylurea Compounds; Proto-Oncogene Proteins c-bcl-2; Pyridines; Sulfonamides; Triazines

2019
[Novel therapies for acute myeloid leukemia based on genomic aberrations].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2019, Volume: 60, Issue:6

    Topics: Cytarabine; Enzyme Inhibitors; Genomics; Humans; Japan; Leukemia, Myeloid, Acute; Protein Kinase Inhibitors

2019
Comprehensive genetic analysis of cytarabine sensitivity in a cell-based model identifies polymorphisms associated with outcome in AML patients.
    Blood, 2013, May-23, Volume: 121, Issue:21

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Cytarabine; Drug Resistance, Neoplasm; Gene Expression Regulation, Leukemic; Genome-Wide Association Study; Genotype; Humans; Leukemia, Myeloid, Acute; Phenotype; Polymorphism, Single Nucleotide; Treatment Outcome

2013
Meta-analysis of randomised clinical trials comparing idarubicin + cytarabine with daunorubicin + cytarabine as the induction chemotherapy in patients with newly diagnosed acute myeloid leukaemia.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Middle Aged; Publication Bias; Randomized Controlled Trials as Topic; Treatment Outcome

2013
Development of a curative treatment within the AML-BFM studies.
    Klinische Padiatrie, 2013, Volume: 225 Suppl 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Etoposide; Germany; Humans; Idarubicin; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Methotrexate; Multicenter Studies as Topic; Prednisone; Randomized Controlled Trials as Topic; Survival Rate; Thioguanine; Vincristine

2013
Rapid induction of complete molecular remission by sequential therapy with LDAC and sorafenib in FLT3-ITD-positive patients unfit for intensive treatment: two cases and review of the literature.
    Journal of hematology & oncology, 2013, Jun-11, Volume: 6

    Topics: Aged; Antibody Specificity; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Lymphocytes; Middle Aged; Niacinamide; Phenylurea Compounds; Prognosis; Remission Induction; Sorafenib

2013
Alternative novel therapies for the treatment of elderly acute myeloid leukemia patients.
    Expert review of hematology, 2013, Volume: 6, Issue:6

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Cytarabine; Daunorubicin; Humans; Immunoconjugates; Immunologic Factors; Leukemia, Myeloid, Acute; Prognosis; Purine Nucleosides; Risk Factors; Stem Cell Transplantation; Transplantation, Autologous

2013
Important milestones in acute leukemia in 2013.
    Best practice & research. Clinical haematology, 2013, Volume: 26, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Hematopoietic Stem Cell Transplantation; History, 20th Century; History, 21st Century; Humans; Leukemia, Myeloid, Acute; Mutation; Neoplasm Proteins; Remission Induction; Survival Analysis

2013
Relapsed acute myeloid leukemia: why is there no standard of care?
    Best practice & research. Clinical haematology, 2013, Volume: 26, Issue:3

    Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Molecular Targeted Therapy; Prognosis; Randomized Controlled Trials as Topic; Recurrence; Remission Induction; Salvage Therapy; Standard of Care; Survival Analysis; Transplantation, Homologous

2013
The euphoria of hypomethylating agents in MDS and AML: is it justified?
    Best practice & research. Clinical haematology, 2013, Volume: 26, Issue:3

    Topics: Aged; Antimetabolites, Antineoplastic; Azacitidine; Cytarabine; Decitabine; DNA Methylation; Endpoint Determination; Humans; Leukemia, Myeloid, Acute; Middle Aged; Myelodysplastic Syndromes; Patient Selection; Randomized Controlled Trials as Topic; Remission Induction; Survival Analysis; Treatment Outcome

2013
Core-binding factor acute myeloid leukemia: can we improve on HiDAC consolidation?
    Hematology. American Society of Hematology. Education Program, 2013, Volume: 2013

    Topics: Antimetabolites, Antineoplastic; Cell Transformation, Neoplastic; Chromosome Inversion; Chromosomes, Human; Cytarabine; Drug Delivery Systems; Humans; Leukemia, Myeloid, Acute; Proto-Oncogene Proteins c-kit; Translocation, Genetic

2013
[Myelodysplastic syndromes: treatment strategy up-to-date].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2014, Volume: 55, Issue:1

    Topics: Antilymphocyte Serum; Azacitidine; Benzoates; Cyclosporine; Cytarabine; Deferasirox; Disease Progression; Drug Discovery; Drug Therapy, Combination; Erythropoietin; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Immunosuppressive Agents; Iron Chelating Agents; Lenalidomide; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Quality of Life; Risk Assessment; Thalidomide; Triazoles

2014
[Current therapy for acute myeloid leukemia and acute promyelocytic leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2014, Volume: 55, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Drug Discovery; Etoposide; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Maintenance Chemotherapy; Mercaptopurine; Methotrexate; Molecular Targeted Therapy; Mutation; Recurrence; Tretinoin; Vincristine

2014
Hypomethylating agents and chemotherapy in MDS.
    Best practice & research. Clinical haematology, 2013, Volume: 26, Issue:4

    Topics: Allografts; Anthracyclines; Antimetabolites, Antineoplastic; Cytarabine; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Stem Cell Transplantation

2013
Optimal therapy for adult patients with acute myeloid leukemia in first complete remission.
    Current treatment options in oncology, 2014, Volume: 15, Issue:2

    Topics: Adenine Nucleotides; Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents; Arabinonucleosides; Clofarabine; Cytarabine; Dose-Response Relationship, Drug; Humans; Interleukin-2; Lenalidomide; Leukemia, Myeloid, Acute; Middle Aged; Remission Induction; Stem Cell Transplantation; Thalidomide; Treatment Outcome; Young Adult

2014
Asymmetric anterior uveitis as a delayed complication of treatment with systemic high-dose cytosine-arabinoside: a case report and literature review.
    Ocular immunology and inflammation, 2014, Volume: 22, Issue:4

    Topics: Adult; Cytarabine; Diagnosis, Differential; Humans; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Male; Uveitis, Anterior

2014
Decitabine. Acute myeloid leukaemia: no progress.
    Prescrire international, 2014, Volume: 23, Issue:148

    Topics: Age Factors; Aged; Animals; Antimetabolites, Antineoplastic; Azacitidine; Cytarabine; Decitabine; Humans; Leukemia, Myeloid, Acute; Patient Selection; Risk Factors; Survival Analysis; Time Factors; Treatment Outcome

2014
Volasertib for the treatment of acute myeloid leukemia: a review of preclinical and clinical development.
    Future oncology (London, England), 2014, Volume: 10, Issue:7

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Demyelinating Diseases; Disease-Free Survival; Drug Evaluation, Preclinical; Humans; Leukemia, Myeloid, Acute; Protein Kinase Inhibitors; Pteridines; Randomized Controlled Trials as Topic

2014
GSTT1 and GSTM1 polymorphisms predict treatment outcome for acute myeloid leukemia: a systematic review and meta-analysis.
    Annals of hematology, 2014, Volume: 93, Issue:8

    Topics: Adolescent; Adult; Aged; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; China; Cytarabine; Disease-Free Survival; Female; Gene Deletion; Genotype; Glutathione Transferase; Humans; Inactivation, Metabolic; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Neoplasm Proteins; Odds Ratio; Pharmacogenetics; Remission Induction; Survival Analysis; Treatment Outcome; Young Adult

2014
Addition of gemtuzumab ozogamicin to induction chemotherapy in adult patients with acute myeloid leukaemia: a meta-analysis of individual patient data from randomised controlled trials.
    The Lancet. Oncology, 2014, Volume: 15, Issue:9

    Topics: Adult; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Confidence Intervals; Cytarabine; Daunorubicin; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gemtuzumab; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged; Odds Ratio; Prognosis; Randomized Controlled Trials as Topic; Remission Induction; Risk Assessment; Survival Rate; Treatment Outcome

2014
Myelomastocytic leukemia with aberrant CD25 expression: case report and review of the literature.
    Clinical lymphoma, myeloma & leukemia, 2014, Volume: 14, Issue:5

    Topics: Adenocarcinoma; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Marrow; Brain; Cerebral Hemorrhage; Cytarabine; Fatal Outcome; Humans; Hydroxamic Acids; Idarubicin; Interleukin-2 Receptor alpha Subunit; Leukemia, Myeloid, Acute; Leukemic Infiltration; Male; Mast Cells; Middle Aged; Neoplasms, Second Primary; Neoplastic Stem Cells; Opportunistic Infections; Prostatectomy; Prostatic Neoplasms; Vorinostat

2014
Prognosis and management of acute myeloid leukemia in patients with Down syndrome.
    Expert review of hematology, 2014, Volume: 7, Issue:6

    Topics: Antimetabolites, Antineoplastic; Bone Marrow Transplantation; Child; Cytarabine; Down Syndrome; GATA1 Transcription Factor; Humans; Leukemia, Myeloid, Acute; Prognosis

2014
High-dose cytarabine in acute myeloid leukemia treatment: a systematic review and meta-analysis.
    PloS one, 2014, Volume: 9, Issue:10

    Topics: Clinical Trials as Topic; Cytarabine; Disease-Free Survival; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid, Acute; Remission Induction

2014
The role of Clofarabine in the treatment of adults with acute myeloid leukemia.
    Critical reviews in oncology/hematology, 2015, Volume: 93, Issue:3

    Topics: Adenine Nucleotides; Adult; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clinical Trials as Topic; Clofarabine; Cytarabine; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Remission Induction; Treatment Outcome

2015
Influence of ABCB1 polymorphisms upon the effectiveness of standard treatment for acute myeloid leukemia: a systematic review and meta-analysis of observational studies.
    The pharmacogenomics journal, 2015, Volume: 15, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anthracyclines; ATP Binding Cassette Transporter, Subfamily B; Child; Child, Preschool; Cohort Studies; Cytarabine; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Middle Aged; Observational Studies as Topic; Polymorphism, Genetic; Treatment Outcome; Young Adult

2015
Finding the optimal combination therapy for the treatment of newly diagnosed AML in older patients unfit for intensive therapy.
    Leukemia research, 2015, Volume: 39, Issue:2

    Topics: Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Critical Care; Cytarabine; Decitabine; Female; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Male; Organophosphates; Quinazolines; Quinolones

2015
Is it time to change conventional consolidation chemotherapy for acute myeloid leukemia in CR1?
    Current opinion in hematology, 2015, Volume: 22, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Consolidation Chemotherapy; Core Binding Factors; Cytarabine; Histone Deacetylase Inhibitors; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Prognosis; Treatment Outcome

2015
Minimal residual disease-directed therapy in acute myeloid leukemia.
    Blood, 2015, Apr-09, Volume: 125, Issue:15

    Topics: Adult; Antineoplastic Agents; Core Binding Factor Alpha 2 Subunit; Cytarabine; Female; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Neoplasm, Residual; Oncogene Proteins, Fusion; RUNX1 Translocation Partner 1 Protein

2015
Translocation t(11;19)(q23;q13.1) without MLL Rearrangement in Acute Myeloid Leukemia: Heterogeneity of the 11q23 Breakpoints.
    Acta haematologica, 2015, Volume: 134, Issue:2

    Topics: Aclarubicin; Aged; Antineoplastic Combined Chemotherapy Protocols; Chromosome Breakpoints; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 19; Cytarabine; Fatal Outcome; Female; Granulocyte Colony-Stimulating Factor; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Recurrence; Translocation, Genetic

2015
Hypertension and Life-Threatening Bleeding in Children with Relapsed Acute Myeloblastic Leukemia Treated with FLT3 Inhibitors.
    Turkish journal of haematology : official journal of Turkish Society of Haematology, 2015, Volume: 32, Issue:3

    Topics: Acidosis; Acute Kidney Injury; Adenine Nucleotides; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Child; Child, Preschool; Clofarabine; Cytarabine; Fatal Outcome; Female; fms-Like Tyrosine Kinase 3; Hemorrhage; Humans; Hypertension; Indoles; Leukemia, Myeloid, Acute; Male; Neoplasm Proteins; Niacinamide; Pain; Pancytopenia; Phenylurea Compounds; Protease Inhibitors; Pyrroles; Salvage Therapy; Sepsis; Sorafenib; Sunitinib

2015
Vosaroxin is a novel topoisomerase-II inhibitor with efficacy in relapsed and refractory acute myeloid leukaemia.
    Expert opinion on pharmacotherapy, 2015, Volume: 16, Issue:9

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Humans; Leukemia, Myeloid, Acute; Naphthyridines; Recurrence; Thiazoles; Topoisomerase Inhibitors; Treatment Failure

2015
Role of drug transport and metabolism in the chemoresistance of acute myeloid leukemia.
    Blood reviews, 2016, Volume: 30, Issue:1

    Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Biological Transport; Biomarkers, Pharmacological; Biotransformation; Cytarabine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Humans; Leukemia, Myeloid, Acute; Precision Medicine; Prodrugs

2016
Chemotherapy options for previously untreated acute myeloid leukemia.
    Expert opinion on pharmacotherapy, 2015, Volume: 16, Issue:14

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase III as Topic; Colony-Stimulating Factors; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Randomized Controlled Trials as Topic; Remission Induction

2015
Acute Myeloid Leukemia.
    The New England journal of medicine, 2015, Sep-17, Volume: 373, Issue:12

    Topics: Antineoplastic Agents; Combined Modality Therapy; Cytarabine; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Mutation; Prognosis; Remission Induction; Signal Transduction

2015
D-CAG (decitabine followed by cytarabine, aclarubicin, and G-CSF) for relapsed acute myeloid leukemia after hematopoietic cell transplantation.
    Annals of hematology, 2016, Volume: 95, Issue:1

    Topics: Aclarubicin; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Combined Modality Therapy; Cytarabine; Decitabine; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Young Adult

2016
The priming induction regimen of HAG as a low dose chemotherapy strategy in AML clonal evolution.
    Science China. Life sciences, 2015, Volume: 58, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clonal Evolution; Cytarabine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Granulocyte Colony-Stimulating Factor; Harringtonines; Homoharringtonine; Humans; Leukemia, Myeloid, Acute; Treatment Outcome

2015
A systematic review and meta-analysis of the impact of WT1 polymorphism rs16754 in the effectiveness of standard chemotherapy in patients with acute myeloid leukemia.
    The pharmacogenomics journal, 2016, Volume: 16, Issue:1

    Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Cytarabine; Etoposide; Genetic Association Studies; Humans; Leukemia, Myeloid, Acute; Observational Studies as Topic; Polymorphism, Single Nucleotide; Survival Analysis; WT1 Proteins

2016
[Superior sagittal sinus thrombosis after intrathecal chemotherapy and intravenous high-dose cytarabine in an acute myeloid leukemia case with t(8;21)(q22;q22)].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2016, Volume: 57, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Cytarabine; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Remission Induction; Sagittal Sinus Thrombosis

2016
[Drug treatment of acute myelogenous leukaemia. Current options and future perspectives].
    Orvosi hetilap, 2016, May-29, Volume: 157, Issue:22

    Topics: Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Humans; Induction Chemotherapy; Karnofsky Performance Status; Leukemia, Myeloid, Acute; Middle Aged; Molecular Targeted Therapy; Quality of Life; Survival Analysis; Treatment Outcome

2016
What Is the Optimal Induction Therapy for Younger Fit Patients With AML?
    Current hematologic malignancy reports, 2016, Volume: 11, Issue:5

    Topics: Anthracyclines; Antimetabolites, Antineoplastic; Cytarabine; Drug Therapy, Combination; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Molecular Targeted Therapy; Prognosis; Remission Induction; Survival Rate

2016
Molecular and Pharmacologic Properties of the Anticancer Quinolone Derivative Vosaroxin: A New Therapeutic Agent for Acute Myeloid Leukemia.
    Drugs, 2016, Volume: 76, Issue:13

    Topics: Aged; Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Double-Blind Method; Haplorhini; Humans; Leukemia, Myeloid, Acute; Mice; Middle Aged; Naphthyridines; Quinolones; Rats; Thiazoles

2016
HAG (Homoharringtonine, Cytarabine, G-CSF) Regimen for the Treatment of Acute Myeloid Leukemia and Myelodysplastic Syndrome: A Meta-Analysis with 2,314 Participants.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Harringtonines; Homoharringtonine; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Survival Analysis; Treatment Outcome; Young Adult

2016
Intussusception: a rare complication in a patient with acute leukaemia after consolidation chemotherapy.
    BMJ case reports, 2017, Feb-28, Volume: 2017

    Topics: Abdominal Pain; Antimetabolites, Antineoplastic; Consolidation Chemotherapy; Cytarabine; Female; Humans; Ileal Diseases; Intussusception; Leukemia, Myeloid, Acute; Middle Aged

2017
Arsenic and old lace: novel approaches in elderly patients with acute myeloid leukemia.
    Seminars in hematology, 2008, Volume: 45, Issue:3 Suppl 2

    Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Clinical Trials as Topic; Cytarabine; Humans; Leukemia, Myeloid, Acute; Middle Aged; Oxides; Treatment Outcome

2008
[Klinefelter syndrome and acute myeloblastic leukaemia].
    Presse medicale (Paris, France : 1983), 2009, Volume: 38, Issue:6

    Topics: Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Examination; Chromosomes, Human, Pair 10; Chromosomes, Human, Pair 8; Cytarabine; Cytogenetics; Genetic Predisposition to Disease; Humans; Idarubicin; In Situ Hybridization, Fluorescence; Karyotyping; Klinefelter Syndrome; Leukemia, Myeloid, Acute; Male; Trisomy

2009
Successful intensive chemotherapy followed by autologous hematopoietic cell transplantation in a patient with acute myeloid leukemia and hepatosplenic candidiasis: case report and review of literature.
    Transplant infectious disease : an official journal of the Transplantation Society, 2009, Volume: 11, Issue:2

    Topics: Adult; Antifungal Agents; Candida tropicalis; Candidiasis; Caspofungin; Cytarabine; Echinocandins; Female; Fluconazole; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Lipopeptides; Liver Diseases; Radiography; Splenic Diseases; Tomography Scanners, X-Ray Computed

2009
Idiopathic hyperammonemia (IHA) after dose-dense induction chemotherapy for acute myeloid leukemia: Case report and review of the literature.
    Leukemia research, 2009, Volume: 33, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase II as Topic; Cytarabine; Female; fms-Like Tyrosine Kinase 3; Humans; Hyperammonemia; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Mutation; Nuclear Proteins; Nucleophosmin

2009
[Bacillus cereus sepsis and subarachnoid hemorrhage following consolidation chemotherapy for acute myelogenous leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2009, Volume: 50, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bacillaceae Infections; Bacillus cereus; Cytarabine; Fatal Outcome; Humans; Immunocompromised Host; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Opportunistic Infections; Remission Induction; Sepsis; Subarachnoid Hemorrhage

2009
Core binding factor acute myeloid leukemia (CBF-AML): is high-dose Ara-C (HDAC) consolidation as effective as you think?
    Current opinion in hematology, 2009, Volume: 16, Issue:2

    Topics: Core Binding Factors; Cytarabine; Dose-Response Relationship, Drug; Gene Expression Profiling; Humans; Leukemia, Myeloid, Acute; Mutation; Prognosis

2009
Dermatomyositis associated with acute myelocytic leukemia.
    Rheumatology international, 2010, Volume: 30, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Biopsy; Bone Marrow Examination; Cytarabine; Daunorubicin; Dermatomyositis; Electromyography; Fatal Outcome; Female; Glucocorticoids; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Paraneoplastic Syndromes; Prednisolone; Quadriceps Muscle; Treatment Failure

2010
Reappearance of acute myeloid leukemia after almost 23 years of continuous complete remission.
    American journal of hematology, 2009, Volume: 84, Issue:7

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Recurrence; Remission Induction; Time Factors; Young Adult

2009
Acquired acute myelogenous leukemia after therapy for acute promyelocytic leukemia with t(15;17): a case report and review of the literature.
    Puerto Rico health sciences journal, 2009, Volume: 28, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 3; Chromosomes, Human, Pair 7; Cytarabine; Daunorubicin; Drug Synergism; Fatal Outcome; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Methotrexate; Mitoxantrone; Monosomy; Neoplasms, Second Primary; Translocation, Genetic; Tretinoin

2009
Hyperleukocytotic secondary acute myeloid leukemia (AML) with sole monosomy 7 as sequela of Philadelphia-chromosome positive chronic myeloid leukemia (CML).
    European journal of haematology, 2009, Dec-01, Volume: 83, Issue:6

    Topics: Aged; Anemia, Refractory, with Excess of Blasts; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Chromosome Deletion; Chromosomes, Human, Pair 7; Cytarabine; Disease Progression; Fatal Outcome; Humans; Imatinib Mesylate; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative; Leukocytosis; Male; Monosomy; Philadelphia Chromosome; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Selection, Genetic

2009
Genetic factors influencing cytarabine therapy.
    Pharmacogenomics, 2009, Volume: 10, Issue:10

    Topics: 5'-Nucleotidase; Antimetabolites, Antineoplastic; Arabinofuranosylcytosine Triphosphate; Cytarabine; Cytidine Deaminase; Deoxycytidine Kinase; Equilibrative Nucleoside Transporter 1; Forecasting; Genetic Variation; Humans; Leukemia, Myeloid, Acute; Nucleoside Deaminases; Pharmacogenetics; Ribonucleotide Reductases

2009
[History, current status, and future prospects in clinical study of myeloid leukemia].
    Nihon rinsho. Japanese journal of clinical medicine, 2009, Volume: 67, Issue:10

    Topics: Antineoplastic Agents; Benzamides; Cytarabine; Drug Design; Drug Therapy, Combination; Gene Targeting; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Piperazines; Precision Medicine; Pyrimidines; Remission Induction; Risk; Tretinoin

2009
[Combination chemotherapy for acute myeloid leukemia].
    Nihon rinsho. Japanese journal of clinical medicine, 2009, Volume: 67, Issue:10

    Topics: Aged; Aged, 80 and over; Aminoglycosides; Anthracyclines; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Neoplasm Recurrence, Local; Remission Induction; Salvage Therapy

2009
[Characteristics of elderly patients with acute myelogenous leukemia].
    Nihon rinsho. Japanese journal of clinical medicine, 2009, Volume: 67, Issue:10

    Topics: Age Distribution; Aged; Aged, 80 and over; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cytarabine; Hospitals, Municipal; Humans; Japan; Leukemia, Myeloid, Acute; Remission Induction; Spouses

2009
[Standard therapies for acute myeloid leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2009, Volume: 50, Issue:10

    Topics: Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Arsenites; Cytarabine; Daunorubicin; Gemtuzumab; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Remission Induction

2009
[Acute myeloid leukemia trials by Japan Adult Leukemia Study Group (JALSG)].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2009, Volume: 50, Issue:8

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Evidence-Based Medicine; Female; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Japan; Leukemia, Myeloid, Acute; Male; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Remission Induction; Young Adult

2009
Current and emerging therapies for acute myeloid leukemia.
    Clinical therapeutics, 2009, Volume: 31 Pt 2

    Topics: Aged; Anthracyclines; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Enzyme Inhibitors; fms-Like Tyrosine Kinase 3; Hematopoietic Stem Cell Transplantation; Humans; Immunotoxins; Leukemia, Myeloid, Acute

2009
Granulocytic sarcoma of abdomen in acute myeloid leukemia patient with inv(16) and t(6;17) abnormal chromosome: case report and review of literature.
    Leukemia research, 2010, Volume: 34, Issue:7

    Topics: Abdominal Neoplasms; Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Chromosome Inversion; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 17; Chromosomes, Human, Pair 6; Cytarabine; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Remission Induction; Sarcoma, Myeloid; Translocation, Genetic

2010
Therapy of acute myelogenous leukemia in adults.
    Cancer treatment and research, 2010, Volume: 145

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Clinical Trials as Topic; Combined Modality Therapy; Core Binding Factors; Cytarabine; Daunorubicin; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Middle Aged; Neoplasm Proteins; Neoplasm, Residual; Prognosis; Remission Induction; Risk; Salvage Therapy; Treatment Outcome

2010
Chemotherapy for patients with acute myeloid leukemia in first remission.
    Current hematologic malignancy reports, 2006, Volume: 1, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Combined Modality Therapy; Cytarabine; Drug Administration Schedule; Hematopoietic Stem Cell Transplantation; Humans; Immunotherapy; Leukemia, Myeloid, Acute; Middle Aged; Multicenter Studies as Topic; Remission Induction

2006
Novel and emerging drugs for acute myeloid leukemia: pharmacology and therapeutic activity.
    Current medicinal chemistry, 2011, Volume: 18, Issue:5

    Topics: Adenine Nucleotides; Animals; Arabinonucleosides; Azacitidine; Benzamides; Clofarabine; Cytarabine; Cytosine; Daunorubicin; Decitabine; Dioxolanes; Farnesyltranstransferase; Histone Deacetylase Inhibitors; Humans; Hydrazines; Imatinib Mesylate; Leukemia, Myeloid, Acute; Liposomes; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Sulfonamides; TOR Serine-Threonine Kinases; Valproic Acid; Vascular Endothelial Growth Factor Receptor-1

2011
[Acute myelogenous leukemia developed at the 26th week of gestation].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2011, Volume: 52, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cesarean Section; Cytarabine; Female; Humans; Idarubicin; Infant, Low Birth Weight; Infant, Newborn; Leukemia, Myeloid, Acute; Male; Pregnancy; Pregnancy Complications, Hematologic; Pregnancy Outcome; Pregnancy Trimester, Second; Remission Induction

2011
Granulocytic sarcoma of palate. Case report and review of literature.
    The New York state dental journal, 2011, Volume: 77, Issue:3

    Topics: Adolescent; Antineoplastic Agents; Cytarabine; Daunorubicin; Female; Hand; Humans; Leukemia, Myeloid, Acute; Palatal Neoplasms; Sarcoma, Myeloid

2011
Therapy-related acute leukemia with mixed phenotype and t(9;22)(q32;q11.2): a case report and review of the literature.
    Human pathology, 2012, Volume: 43, Issue:4

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Back; Benzamides; Bone Marrow; Chromosomes, Human, Pair 22; Chromosomes, Human, Pair 9; Cytarabine; Endometrial Neoplasms; Female; Gene Rearrangement; Genes, abl; Humans; Idarubicin; Imatinib Mesylate; Immunophenotyping; Induction Chemotherapy; Karyotyping; Leukemia, Myeloid, Acute; Leukemic Infiltration; Middle Aged; Neoplasms, Second Primary; Piperazines; Pyrimidines; Remission Induction; Soft Tissue Neoplasms; Submandibular Gland Neoplasms; Translocation, Genetic

2012
Elacytarabine--lipid vector technology overcoming drug resistance in acute myeloid leukemia.
    Expert opinion on investigational drugs, 2011, Volume: 20, Issue:12

    Topics: Antineoplastic Agents; Cytarabine; Drug Delivery Systems; Drug Discovery; Drug Resistance, Neoplasm; Humans; Leukemia, Myeloid, Acute; Molecular Targeted Therapy

2011
A meta-analysis of CAG (cytarabine, aclarubicin, G-CSF) regimen for the treatment of 1029 patients with acute myeloid leukemia and myelodysplastic syndrome.
    Journal of hematology & oncology, 2011, Nov-14, Volume: 4

    Topics: Aclarubicin; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Treatment Outcome; Young Adult

2011
Should the presence of minimal residual disease (MRD) in morphologic complete remission alter post-remission strategy in AML?
    Best practice & research. Clinical haematology, 2011, Volume: 24, Issue:4

    Topics: Anthracyclines; Antineoplastic Agents; Biomarkers, Tumor; Child; Cytarabine; Disease Management; Humans; Leukemia, Myeloid, Acute; Neoplasm, Residual; Polymerase Chain Reaction; Remission Induction; Stem Cell Transplantation; Transplantation, Homologous; Treatment Outcome

2011
What is the optimal induction strategy for older patients?
    Best practice & research. Clinical haematology, 2011, Volume: 24, Issue:4

    Topics: Age Factors; Aged; Aged, 80 and over; Anthracyclines; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cytarabine; Disease Management; Drug Resistance, Neoplasm; Humans; Karyotype; Leukemia, Myeloid, Acute; Remission Induction; Risk Assessment; Survival Analysis; Treatment Outcome; United States

2011
Is a nadir bone marrow required and, if so, what to do with residual disease?
    Best practice & research. Clinical haematology, 2011, Volume: 24, Issue:4

    Topics: Anthracyclines; Antineoplastic Agents; Biopsy; Bone Marrow; Cytarabine; Cytogenetics; Humans; Leukemia, Myeloid, Acute; Neoplasm, Residual; Practice Guidelines as Topic; Prognosis; Remission Induction; Retrospective Studies; Sensitivity and Specificity; Survival Rate; United States

2011
New induction and postinduction strategies in acute myeloid leukemia.
    Current opinion in hematology, 2012, Volume: 19, Issue:2

    Topics: Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Gemtuzumab; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Mitoxantrone; Prognosis

2012
[Current treatment of acute myeloid leukaemia in adults].
    Orvosi hetilap, 2012, Feb-19, Volume: 153, Issue:7

    Topics: Age Factors; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Boronic Acids; Bortezomib; Cytarabine; Disease-Free Survival; Drug Resistance, Neoplasm; fms-Like Tyrosine Kinase 3; Gemtuzumab; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Leukemia, Myeloid, Acute; Mitoxantrone; Molecular Targeted Therapy; Oxides; Prognosis; Pyrazines; Recurrence; Transplantation, Homologous; Treatment Outcome; Tretinoin

2012
[A systematic review of MA versus IA regimen for patients with acute myelogenous leukemia].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2011, Volume: 32, Issue:12

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Young Adult

2011
Pediatric acute myeloid leukemia.
    Expert review of anticancer therapy, 2012, Volume: 12, Issue:3

    Topics: Anthracyclines; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Clinical Trials as Topic; Complementary Therapies; Cytarabine; Dose-Response Relationship, Drug; Hematopoietic Stem Cell Transplantation; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Maintenance Chemotherapy; Neoplasm, Residual; Secondary Prevention; Survival Rate; Therapies, Investigational; Transplantation, Homologous; Treatment Outcome

2012
Relapse of acute myeloid leukemia at the pituitary gland: a case report and review of literature.
    Endocrine pathology, 2012, Volume: 23, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Diabetes Insipidus; Etoposide; Female; Humans; Hypopituitarism; Idarubicin; Leukemia, Myeloid, Acute; Magnetic Resonance Imaging; Methotrexate; Pituitary Neoplasms; Radiotherapy; Recurrence; Remission Induction; Vision Disorders

2012
High-dose cytarabine (24 g/m2) in combination with idarubicin (HiDAC-3) results in high first-cycle response with limited gastrointestinal toxicity in adult acute myeloid leukaemia.
    Internal medicine journal, 2013, Volume: 43, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Gastrointestinal Tract; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Retrospective Studies; Treatment Outcome; Young Adult

2013
Safety and efficacy of azacitidine in the treatment of elderly patients with myelodysplastic syndrome.
    Clinical interventions in aging, 2012, Volume: 7

    Topics: Age Factors; Aged; Antimetabolites, Antineoplastic; Azacitidine; Chromosome Aberrations; Cytarabine; Disease Progression; Drug Evaluation; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Outcome Assessment, Health Care; Quality of Life; Risk Assessment; Sickness Impact Profile

2012
The clinically relevant pharmacogenomic changes in acute myelogenous leukemia.
    Pharmacogenomics, 2012, Volume: 13, Issue:11

    Topics: Anthracyclines; Cytarabine; DNA-Binding Proteins; Farnesyltranstransferase; Glutathione Transferase; Guanine Nucleotide Exchange Factors; Humans; Leukemia, Myeloid, Acute; Meta-Analysis as Topic; Nuclear Proteins; Pharmacogenetics; Precision Medicine

2012
Current treatment of acute myeloid leukemia.
    Current opinion in oncology, 2012, Volume: 24, Issue:6

    Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Consolidation Chemotherapy; Cytarabine; Decitabine; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Molecular Targeted Therapy; Precision Medicine; Stem Cell Transplantation

2012
A tetraploid minimally differentiated acute myeloblastic leukemia with extensive erythrophagocytosis: a case report and literature review.
    International journal of hematology, 2012, Volume: 96, Issue:6

    Topics: Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cell Differentiation; Cytarabine; Cytophagocytosis; Erythrocytes; Fatal Outcome; Female; HLA-DR Antigens; Humans; Immunophenotyping; Leukemia, Myeloid, Acute; Middle Aged; Mitomycin; Neoplastic Stem Cells; Oncogene Proteins, Fusion; Prognosis; Tetraploidy

2012
Can we improve outcomes in patients with acute myelogenous leukemia? Incorporating HDAC inhibitors into front-line therapy.
    Best practice & research. Clinical haematology, 2012, Volume: 25, Issue:4

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Clinical Trials, Phase I as Topic; Cytarabine; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Idarubicin; Leukemia, Myeloid, Acute; Vorinostat

2012
Is it time to revisit standard post-remission therapy?
    Best practice & research. Clinical haematology, 2012, Volume: 25, Issue:4

    Topics: Adult; Antimetabolites, Antineoplastic; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Remission Induction

2012
Sense and nonsense of high-dose cytarabine for acute myeloid leukemia.
    Blood, 2013, Jan-03, Volume: 121, Issue:1

    Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Consolidation Chemotherapy; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Induction Chemotherapy; Infusions, Intravenous; Leukemia, Myeloid, Acute; Multicenter Studies as Topic; Patient Selection; Randomized Controlled Trials as Topic; Retrospective Studies; Risk; Treatment Outcome

2013
Elacytarabine: lipid vector technology under investigation in acute myeloid leukemia.
    Expert review of hematology, 2013, Volume: 6, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Delivery Systems; Drug Discovery; Humans; Leukemia, Myeloid, Acute; Molecular Targeted Therapy

2013
Tetrasomy 13 as the sole cytogenetic abnormality in acute myeloid leukemia M1 without maturation.
    Cancer genetics and cytogenetics, 2002, Volume: 135, Issue:2

    Topics: Aneuploidy; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 13; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Fatal Outcome; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Thioguanine; Vidarabine

2002
What is the optimal therapy for childhood AML?
    Oncology (Williston Park, N.Y.), 2002, Volume: 16, Issue:8

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Combined Modality Therapy; Cytarabine; Humans; Immunotherapy; Leukemia, Myeloid, Acute

2002
Prognosis of inv(16)/t(16;16) acute myeloid leukemia (AML): a survey of 110 cases from the French AML Intergroup.
    Blood, 2003, Jul-15, Volume: 102, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Chromosome Inversion; Chromosomes, Human, Pair 16; Clinical Trials as Topic; Cytarabine; Daunorubicin; Disease-Free Survival; Female; France; Humans; Idarubicin; Infant; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Life Tables; Male; Middle Aged; Mitoxantrone; Multicenter Studies as Topic; Prognosis; Randomized Controlled Trials as Topic; Remission Induction; Retrospective Studies; Risk Factors; Survival Analysis; Treatment Outcome

2003
Acute myelogenous leukemia in an adult with thrombocytopenia with absent radii syndrome.
    European journal of haematology, 2003, Volume: 70, Issue:4

    Topics: Abnormalities, Multiple; Adult; Antineoplastic Combined Chemotherapy Protocols; Cell Differentiation; Cytarabine; Cytokines; Female; Genetic Predisposition to Disease; Humans; Idarubicin; Leukemia, Myeloid, Acute; Menorrhagia; Neoplasm Proteins; Platelet Count; Proto-Oncogene Proteins; Radius; Receptors, Cytokine; Receptors, Thrombopoietin; Recurrence; Remission Induction; Risk; Syndrome; Thrombocytopenia

2003
[Expanding possibilities, strategic considerations, and novel methods in the diagnosis and chemotherapy of adult acute myeloid leukemia].
    Orvosi hetilap, 2003, Sep-07, Volume: 144, Issue:36

    Topics: Adult; Anthracyclines; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Cytarabine; Drug Resistance, Neoplasm; Gene Expression Profiling; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Oligonucleotide Array Sequence Analysis; Oxides; Palliative Care; Prognosis; Remission Induction; Tretinoin

2003
[Hematologic tumors].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Cytarabine; Dacarbazine; Daunorubicin; Doxorubicin; Hematologic Neoplasms; Hodgkin Disease; Humans; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Mechlorethamine; Prednisone; Procarbazine; Vinblastine; Vincristine

2003
Fatal hemorrhagic pneumonia caused by infection due to Kytococcus sedentarius--a pathogen or passenger?
    Annals of hematology, 2004, Volume: 83, Issue:7

    Topics: Actinomycetales; Actinomycetales Infections; Acyclovir; Antineoplastic Combined Chemotherapy Protocols; Bacteremia; Bacterial Translocation; Cefepime; Cephalosporins; Clostridium Infections; Colistin; Cytarabine; Daunorubicin; Drug Therapy, Combination; Etoposide; Fatal Outcome; Hemoptysis; Humans; Hydroxyurea; Immunocompromised Host; Intestinal Mucosa; Leukemia, Myeloid, Acute; Male; Metronidazole; Middle Aged; Neutropenia; Pneumonia, Bacterial; Superinfection; Teicoplanin; Trimethoprim, Sulfamethoxazole Drug Combination

2004
Acute myeloid leukemia with t(8;21)(q22;q22) manifesting as granulocytic sarcomas in the rhinopharynx and external acoustic meatus at relapse after high-dose cytarabine: case report and review of the literature.
    The hematology journal : the official journal of the European Haematology Association, 2004, Volume: 5, Issue:1

    Topics: Adult; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Cytarabine; Ear; Female; Humans; Leukemia, Myeloid, Acute; Nasopharynx; Peripheral Blood Stem Cell Transplantation; Radiotherapy; Recurrence; Remission Induction; Sarcoma, Myeloid; Translocation, Genetic

2004
[Recent advances in the treatment of acute myelogenous leukemia: a view of the new agents].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2003, Volume: 44, Issue:12

    Topics: Alkyl and Aryl Transferases; Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Benzoates; Cyclosporine; Cytarabine; Daunorubicin; Drug Design; Farnesyltranstransferase; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Neoplasm Recurrence, Local; Nucleosides; Oxides; Prognosis; Radioisotopes; Remission Induction; Tetrahydronaphthalenes; Topoisomerase Inhibitors; Tretinoin; Verapamil

2003
Granulocytic sarcoma of the testis.
    Urology, 2004, Volume: 63, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cell Nucleolus; Chemotherapy, Adjuvant; Chromatin; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease Progression; Humans; Leukemia, Myeloid, Acute; Male; Methotrexate; Orchiectomy; Radiotherapy, Adjuvant; Sarcoma, Myeloid; Testicular Neoplasms

2004
Acute myeloblastic leukemia in pregnancy: a case report and review of the literature.
    European journal of gynaecological oncology, 2004, Volume: 25, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Diagnosis, Differential; Drug Administration Schedule; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Pregnancy; Pregnancy Complications, Neoplastic; Pregnancy Trimester, Third

2004
Assessment of drug resistance in acute myeloid leukemia.
    Expert review of molecular diagnostics, 2004, Volume: 4, Issue:5

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cytarabine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Humans; Leukemia, Myeloid, Acute; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Reverse Transcriptase Polymerase Chain Reaction; Vault Ribonucleoprotein Particles

2004
A randomized trial of continuous infusion versus bolus mitoxantrone in combination with cytarabine in newly diagnosed patients with acute myeloblastic leukemia.
    Hematological oncology, 2004, Volume: 22, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Remission Induction; Time Factors; Treatment Outcome

2004
Management of patients with systemic mastocytosis: review of M. D. Anderson Cancer Center experience.
    American journal of hematology, 2004, Volume: 77, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Cladribine; Combined Modality Therapy; Cytarabine; Female; Humans; Idarubicin; Imatinib Mesylate; Interferon-alpha; Leukemia, Myeloid, Acute; Male; Mastocytosis, Systemic; Middle Aged; Myelodysplastic Syndromes; Piperazines; Prospective Studies; Pyrimidines; Stem Cell Transplantation; Treatment Outcome

2004
Substrate cycles and drug resistance to 1-beta-D-arabinofuranosylcytosine (araC).
    Leukemia & lymphoma, 2005, Volume: 46, Issue:3

    Topics: Adult; Cytarabine; Deoxyribonucleotides; Drug Resistance, Neoplasm; Humans; Leukemia, Myeloid, Acute; Models, Biological; Substrate Cycling

2005
Therapy-related myelodysplastic syndrome with monosomy 5 after successful treatment of acute myeloid leukemia (M2).
    American journal of hematology, 2005, Volume: 79, Issue:2

    Topics: Anthracyclines; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 5; Cytarabine; Cytogenetic Analysis; Etoposide; Fatal Outcome; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Monosomy; Myelodysplastic Syndromes

2005
The use of liposomal daunorubicin (DaunoXome) in acute myeloid leukemia.
    Leukemia & lymphoma, 2005, Volume: 46, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Agents; Child; Child, Preschool; Clinical Trials as Topic; Cytarabine; Daunorubicin; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Remission Induction

2005
Severe toxicity following induction chemotherapy for acute myelogenous leukemia in a patient with Werner's syndrome.
    Leukemia & lymphoma, 2005, Volume: 46, Issue:7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; DNA Helicases; Etoposide; Exodeoxyribonucleases; Humans; Leukemia, Myeloid, Acute; Male; Mitoxantrone; RecQ Helicases; Werner Syndrome; Werner Syndrome Helicase

2005
Treatment of older patients with AML.
    Critical reviews in oncology/hematology, 2005, Volume: 56, Issue:2

    Topics: Adult; Age Factors; Aged; Antibodies, Monoclonal; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Middle Aged; Protein Kinase Inhibitors; Remission Induction; Stem Cell Transplantation; Thioguanine; Transplantation, Homologous

2005
High-dose cytosine arabinoside in the treatment of acute myeloid leukemia: Review of three randomized trials.
    Cancer, 2006, Jul-01, Volume: 107, Issue:1

    Topics: Adolescent; Adult; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid, Acute; Middle Aged; Randomized Controlled Trials as Topic

2006
Acute myeloid leukemia with T-cell receptor gamma gene rearrangement occurring in a patient with chronic lymphocytic leukemia: a case report.
    American journal of hematology, 2007, Volume: 82, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor; Humans; Idarubicin; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Male; Neoplasms, Second Primary; Remission Induction

2007
[Current therapeutic strategies in the management of acute myeloid leukemia].
    Medizinische Klinik (Munich, Germany : 1983), 2007, Apr-15, Volume: 102, Issue:4

    Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Bone Marrow; Bone Marrow Purging; Bone Marrow Transplantation; Cytarabine; Disease-Free Survival; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Prognosis; Remission Induction; Retreatment

2007
[Treatment for acute myeloid leukemia: introduction].
    Nihon rinsho. Japanese journal of clinical medicine, 2007, Jan-28, Volume: 65 Suppl 1

    Topics: Antimetabolites, Antineoplastic; Cytarabine; Humans; Leukemia, Myeloid, Acute; Prognosis; Randomized Controlled Trials as Topic; Remission Induction

2007
Infections with viridans group streptococci in children with cancer.
    Pediatric blood & cancer, 2007, Volume: 49, Issue:6

    Topics: Antibiotic Prophylaxis; Child; Child, Preschool; Cytarabine; Humans; Incidence; Leukemia, Myeloid, Acute; Myocarditis; Nervous System Diseases; Neutropenia; Practice Guidelines as Topic; Respiratory Distress Syndrome; Shock, Septic; Stem Cell Transplantation; Streptococcal Infections; Viridans Streptococci

2007
Long-term propylthiouracil use and acute myeloid leukemia: a case report and review of the literature.
    Annals of hematology, 2008, Volume: 87, Issue:3

    Topics: Adult; Antimetabolites; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 2; Chromosomes, Human, Pair 21; Cytarabine; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Iodide Peroxidase; Leukemia, Myeloid, Acute; Peroxidase; Propylthiouracil; Remission Induction; Time Factors; Translocation, Genetic; Transplantation, Homologous

2008
Acute myeloid leukemia.
    Pediatric clinics of North America, 2008, Volume: 55, Issue:1

    Topics: Adolescent; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Clinical Trials as Topic; Cytarabine; Humans; Infant; Leukemia, Myeloid, Acute; Pharmacogenetics; Prognosis; Remission Induction; Risk Factors; Stem Cell Transplantation

2008
Consolidation therapy: what should be the standard of care?
    Best practice & research. Clinical haematology, 2008, Volume: 21, Issue:1

    Topics: Adolescent; Adult; Age Factors; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Clinical Trials as Topic; Cytarabine; Disease-Free Survival; Humans; Leukemia, Myeloid, Acute; Middle Aged; Neoplasm Recurrence, Local; Remission Induction

2008
Acute myeloid leukemia in the elderly: conventional and novel treatment approaches.
    Blood reviews, 2008, Volume: 22, Issue:4

    Topics: Adenine Nucleotides; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antineoplastic Agents; Arabinonucleosides; Arsenic Trioxide; Arsenicals; Azacitidine; Clofarabine; Cytarabine; Hematopoietic Stem Cell Transplantation; Humans; Hydrazines; Idarubicin; Leukemia, Myeloid, Acute; Middle Aged; Oxides; Recurrence; Sulfonamides

2008
Treatment of relapsed acute myeloid leukaemia.
    Reviews on recent clinical trials, 2006, Volume: 1, Issue:2

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colony-Stimulating Factors; Cytarabine; Etoposide; Humans; Immunity, Innate; Immunologic Factors; Leukemia, Myeloid, Acute; Mitoxantrone; Randomized Controlled Trials as Topic; Secondary Prevention

2006
[Acute promyelocytic leukemia. Review of the literature].
    Minerva medica, 1984, Jul-31, Volume: 75, Issue:30-31

    Topics: Acute Disease; Adolescent; Adult; Aged; Anemia; Antibiotics, Antineoplastic; Child; Child, Preschool; Cytarabine; Daunorubicin; Disseminated Intravascular Coagulation; Female; Heparin; Humans; Inclusion Bodies; Leukemia, Myeloid, Acute; Male; Middle Aged; Naphthacenes; Neoplastic Stem Cells; Thioguanine; Translocation, Genetic

1984
Adult acute nonlymphocytic leukemias.
    The Medical clinics of North America, 1980, Volume: 64, Issue:4

    Topics: Acute Disease; Aged; Anemia; Anemia, Aplastic; Anemia, Sideroblastic; Blood Transfusion; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Drug Resistance; Female; Hemorrhage; Humans; Immunotherapy; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Platelet Transfusion; Spinal Cord; Syndrome

1980
[The clinical significance of the Philadelphia chromosome in acute leukaemia (author's transl)].
    Wiener klinische Wochenschrift, 1980, Aug-01, Volume: 92, Issue:15

    Topics: Acute Disease; Adult; Blood Transfusion; Chromosomes, Human, 21-22 and Y; Cytarabine; Female; Glucocorticoids; Hematopoietic Stem Cells; Humans; Leukapheresis; Leukemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Vincristine

1980
Biochemical pharmacological determinants of drug action in cancer therapeutics.
    Oncology, 1980, Volume: 37 Suppl 1

    Topics: Animals; Biotransformation; Cytarabine; Humans; Leukemia L1210; Leukemia, Myeloid, Acute; Methotrexate; Mice; Rats

1980
Renewal and determination in leukemic blast populations.
    Journal of cellular physiology. Supplement, 1982, Volume: 1

    Topics: Antibodies, Monoclonal; Cell Differentiation; Cell Division; Cells, Cultured; Cytarabine; Doxorubicin; Genes; Granulocytes; Hematopoietic Stem Cells; Humans; Leukemia; Leukemia, Myeloid, Acute; Models, Biological; Phytohemagglutinins; Transfection

1982
The treatment of acute myelogenous leukemia in adults.
    Seminars in hematology, 1982, Volume: 19, Issue:3

    Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Bone Marrow; Cell Transformation, Neoplastic; Cytarabine; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Middle Aged; Naphthacenes; Prednisolone; Prognosis; Regression Analysis; Thioguanine; Time Factors; Vincristine

1982
[Complete remission achieved by low-dose Ara-C, aclarubicin and rhG-CSF (CAG) therapy in acute non-lymphocytic leukemia with monosomy 7 occurring after severe aplastic anemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1995, Volume: 36, Issue:2

    Topics: Aclarubicin; Adult; Aged; Anemia, Aplastic; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 7; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Monosomy; Recombinant Proteins; Remission Induction

1995
Therapy-related acute leukemia associated with t(11q23) after primary acute myeloid leukemia with t(8;21): a report of two cases.
    Blood, 1995, Nov-01, Volume: 86, Issue:9

    Topics: Anemia, Refractory, with Excess of Blasts; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cell Lineage; Child; Child, Preschool; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Cytarabine; Enzyme Inhibitors; Etoposide; Fatal Outcome; Female; Humans; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Mitoxantrone; Neoplasms, Second Primary; Oncogenes; Topoisomerase II Inhibitors; Translocation, Genetic

1995
rHuGM-CSF after high-dose chemotherapy in post-remission acute leukemia.
    Stem cells (Dayton, Ohio), 1995, Volume: 13, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Etoposide; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recombinant Proteins

1995
Chemotherapy in acute myelogenous leukemia: high dose, higher expectations?
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1995, Volume: 13, Issue:1

    Topics: Age Factors; Cytarabine; Daunorubicin; Drug Administration Schedule; Humans; Leukemia, Myeloid, Acute; Randomized Controlled Trials as Topic; Remission Induction

1995
Toxic megacolon complicating chemotherapy for acute myeloid leukaemia.
    Postgraduate medical journal, 1994, Volume: 70, Issue:830

    Topics: Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Megacolon, Toxic

1994
[Progress of chemotherapy in adult acute leukemia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1995, Volume: 22, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Disease-Free Survival; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Remission Induction; Survival Rate

1995
[A case of acute nonlymphocytic leukemia with leukemic cell infiltration to the uterus followed by bone marrow relapse].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1994, Volume: 35, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Leukemic Infiltration; Mercaptopurine; Prednisolone; Recurrence; Remission Induction; Uterus; Vincristine

1994
Epipodophyllotoxins in the treatment of childhood cancer.
    Cancer chemotherapy and pharmacology, 1994, Volume: 34 Suppl

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Cytarabine; Etoposide; Humans; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Neoplasms; Neoplasms, Second Primary; Neuroblastoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Teniposide

1994
Poor prognosis acute myelogenous leukemia.
    Leukemia & lymphoma, 1993, Volume: 9, Issue:4-5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Bone Marrow Transplantation; Cell Division; Cytarabine; Daunorubicin; Drug Resistance; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Hodgkin Disease; Humans; Leukemia, Myeloid, Acute; Leukemia, Radiation-Induced; Neoplasms, Second Primary; Neoplastic Stem Cells; Preleukemia; Prognosis; Recombinant Proteins; Remission Induction; Retrospective Studies; Risk Factors; Salvage Therapy; Survival Analysis; Treatment Failure

1993
Fludarabine for treatment of adult acute myelogenous leukemia.
    Leukemia & lymphoma, 1993, Volume: 11 Suppl 2

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Vidarabine

1993
Acute myelogenous leukemia associated with a mediastinal tumor.
    Leukemia & lymphoma, 1993, Volume: 12, Issue:1-2

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Humans; Leukapheresis; Leukemia, Myeloid, Acute; Mediastinal Neoplasms; Mercaptopurine; Middle Aged; Prednisolone; Radiography, Thoracic; Remission Induction; Time Factors; Tomography, X-Ray Computed

1993
Clinical review on features and cytogenetic patterns in adult acute myeloid leukemia with lymphoid markers.
    Leukemia & lymphoma, 1993, Volume: 9, Issue:4-5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aneuploidy; Antigens, CD; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Chromosome Aberrations; Cytarabine; DNA Nucleotidylexotransferase; Etoposide; Female; Gene Rearrangement; Humans; Immunophenotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Proteins; Neoplastic Stem Cells; Philadelphia Chromosome; Remission Induction; Vindesine

1993
Two additional cases of acute myeloid leukemia with t(7;11)(p15;p15) having low neutrophil alkaline phosphatase scores.
    Cancer genetics and cytogenetics, 1993, Jul-15, Volume: 68, Issue:2

    Topics: Acute Disease; Adult; Alkaline Phosphatase; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 7; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Neutrophils; Prednisolone; Primary Myelofibrosis; Remission Induction; Translocation, Genetic

1993
Chemotherapy for minimally differentiated acute myeloid leukemia (AML-M0). A report on five cases and review of the literature.
    Annals of hematology, 1993, Volume: 66, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Azo Compounds; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Naphthalenes; Peroxidase; Prednisolone; Remission Induction

1993
Filamentous degeneration of neurons. A possible feature of cytosine arabinoside neurotoxicity.
    Cancer, 1993, Feb-15, Volume: 71, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Stem; Cell Nucleus; Cytarabine; Humans; Intermediate Filaments; Kidney Tubular Necrosis, Acute; Leukemia, Myeloid, Acute; Male; Motor Neurons; Nerve Degeneration; Neurons; Spinal Cord

1993
Biochemical modulation of arabinosylcytosine for therapy of leukemias.
    Leukemia & lymphoma, 1993, Volume: 10 Suppl

    Topics: Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Cytarabine; Humans; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Vidarabine

1993
Is intensive treatment beneficial to elderly patients with ANLL?
    Hematological oncology, 1993, Volume: 11 Suppl 1

    Topics: Acute Disease; Aged; Cytarabine; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Prognosis; Recurrence; Remission Induction

1993
[Bases for intravenous administration of cytosine arabinoside in the treatment of adult acute myeloid leukemia].
    Bulletin du cancer, 1995, Volume: 82, Issue:11

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Drug Synergism; Hematopoietic Cell Growth Factors; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Remission Induction; Salvage Therapy; Vidarabine

1995
Postremission therapy of acute myeloid leukemia in older adults.
    Leukemia, 1996, Volume: 10 Suppl 1

    Topics: Adolescent; Adult; Age Factors; Aged; Antimetabolites, Antineoplastic; Cytarabine; Disease-Free Survival; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Middle Aged; Randomized Controlled Trials as Topic; Remission Induction

1996
[Chemotherapy of relapsed AML and ALL].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1996, Volume: 37, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cytarabine; Etoposide; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Mechlorethamine; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prednisone; Procarbazine; Recurrence; Remission Induction; Vinblastine

1996
Primary extramedullary leukemia of the prostate: case report and review of the literature.
    American journal of hematology, 1996, Volume: 53, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Diagnostic Errors; Doxorubicin; Humans; Idarubicin; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Middle Aged; Prednisone; Prostatectomy; Prostatic Neoplasms; Radioisotope Teletherapy; Remission Induction; Urinary Retention; Vincristine

1996
Haemopoietic growth factors, the cell cycle of acute myeloblastic leukaemia progenitors and sensitivity to cytosine arabinoside.
    Leukemia & lymphoma, 1996, Volume: 23, Issue:5-6

    Topics: Antimetabolites, Antineoplastic; Cell Cycle; Cytarabine; Cytokines; Drug Screening Assays, Antitumor; Hematopoietic Cell Growth Factors; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Recombinant Proteins

1996
The management of acute myeloid leukaemia (AML) in human immunodeficiency virus (HIV) infection: a case report and review.
    International journal of STD & AIDS, 1997, Volume: 8, Issue:4

    Topics: Adult; Anti-HIV Agents; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Cytarabine; Daunorubicin; Drug Therapy, Combination; HIV Infections; Humans; Leukemia, Myeloid, Acute; Male; Thioguanine; Zidovudine

1997
[Recent advances on the treatment of acute childhood leukemia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Daunorubicin; Disease-Free Survival; Doxorubicin; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Remission Induction; Survival Rate; Treatment Outcome; Vincristine

1997
[Progress in the treatment of adult acute myeloid leukemia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:9

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Mercaptopurine; Middle Aged; Prednisolone; Tretinoin

1997
Mitoxantrone in the treatment of acute myelogenous leukemia: a review.
    Hematology and cell therapy, 1997, Volume: 39, Issue:4

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Genes, MDR; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Randomized Controlled Trials as Topic

1997
[Update on malignant hematologic diseases].
    Bulletin du cancer, 1998, Volume: 85, Issue:1

    Topics: Antineoplastic Agents; Cytarabine; Humans; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Multiple Myeloma

1998
[The causes of treatment ineffectiveness in acute myelogenous leukemia--the role of blast resistance to cytotoxic drugs].
    Przeglad lekarski, 1998, Volume: 55, Issue:7-8

    Topics: Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Marrow Cells; Cyclosporine; Cyclosporins; Cytarabine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Leukemia, Myeloid, Acute; Middle Aged; Survival Rate

1998
Es nucleoside transporter content of acute leukemia cells: role in cell sensitivity to cytarabine (araC).
    Leukemia & lymphoma, 1998, Volume: 32, Issue:1-2

    Topics: Acute Disease; Antimetabolites, Antineoplastic; Carrier Proteins; Cytarabine; Drug Resistance, Neoplasm; Flow Cytometry; Fluoresceins; Gene Expression; Humans; Leukemia, Myeloid, Acute; Lymphocytes; Membrane Proteins; Microscopy, Confocal; Nucleoside Transport Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Purine Nucleosides

1998
Down syndrome and acute myeloid leukemia. Lessons learned from experience with high-dose Ara-C containing regimens.
    Advances in experimental medicine and biology, 1999, Volume: 457

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Deoxycytosine Nucleotides; Disease-Free Survival; Dose-Response Relationship, Drug; Down Syndrome; Humans; Leukemia, Myeloid, Acute

1999
New developments in the treatment of acute myeloid leukemia.
    Advances in experimental medicine and biology, 1999, Volume: 457

    Topics: Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Colony-Stimulating Factors; Cytarabine; Drug Resistance, Multiple; Gene Expression Regulation, Neoplastic; Genes, MDR; Humans; Leukemia, Myeloid, Acute; Remission Induction

1999
Fatal disseminated infection by Scedosporium prolificans during induction therapy for acute leukemia: a case report and literature review.
    Pathology, 1999, Volume: 31, Issue:4

    Topics: Aged; Amphotericin B; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Resistance, Microbial; Fatal Outcome; Female; Fungemia; Humans; Immunocompromised Host; Leukemia, Myeloid, Acute; Mycetoma; Pseudallescheria

1999
High dose cytarabine or transplantation for consolidation of younger patients with acute myeloid leukemia.
    Current opinion in oncology, 2000, Volume: 12, Issue:2

    Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Bone Marrow Transplantation; Clinical Trials as Topic; Cytarabine; Disease-Free Survival; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis

2000
[Prognostic factors in chemotherapies for acute myeloid leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2000, Volume: 41, Issue:4

    Topics: Antineoplastic Agents; Clinical Trials as Topic; Cytarabine; Humans; Karyotyping; Leukemia, Myeloid, Acute; Multicenter Studies as Topic; Prognosis; Risk Factors; Survival Analysis; Tretinoin

2000
[Acute myelogenous leukemia in elderly patients].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 2000, Volume: 37, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Humans; Leukemia, Myeloid, Acute; Middle Aged; Prognosis; Quality of Life; Remission Induction

2000
New strategies in the treatment of acute myelogenous leukemia: mobilization and transplantation of autologous peripheral blood stem cells in adult patients.
    Stem cells (Dayton, Ohio), 2000, Volume: 18, Issue:5

    Topics: Adult; Clinical Trials as Topic; Combined Modality Therapy; Cytarabine; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Transplantation, Autologous

2000
Molecular and clinical advances in core binding factor primary acute myeloid leukemia: a paradigm for translational research in malignant hematology.
    Cancer investigation, 2000, Volume: 18, Issue:8

    Topics: Animals; Antimetabolites, Antineoplastic; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Core Binding Factor alpha Subunits; Cytarabine; Diagnosis, Differential; DNA-Binding Proteins; Humans; Leukemia, Myeloid, Acute; Neoplasm, Residual; Prognosis; Randomized Controlled Trials as Topic; Remission Induction; Retrospective Studies; Survival Analysis; Transcription Factor AP-2; Transcription Factors; Translocation, Genetic; Treatment Outcome

2000
Bilateral breast relapse in acute myelogenous leukemia.
    Journal of pediatric hematology/oncology, 2001, Volume: 23, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bone Marrow Transplantation; Breast; Child; Combined Modality Therapy; Cytarabine; Daunorubicin; Dexamethasone; Etoposide; Female; Graft vs Host Disease; Humans; Idarubicin; Immunologic Factors; Interleukin-2; Leukemia, Myeloid, Acute; Leukemic Infiltration; Radiotherapy, High-Energy; Recurrence; Salvage Therapy; Thioguanine; Transplantation Conditioning; Vidarabine

2001
Therapeutic options for acute myelogenous leukemia.
    Cancer, 2001, Sep-01, Volume: 92, Issue:5

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Bone Marrow Transplantation; Clinical Trials as Topic; Colony-Stimulating Factors; Cytarabine; Cytogenetics; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Prognosis; Topotecan; Vidarabine

2001
Donor cell-derived acute myeloid leukemia developing 14 months after matched unrelated bone marrow transplantation for chronic myeloid leukemia.
    Bone marrow transplantation, 2001, Volume: 28, Issue:7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Bone Marrow Transplantation; Combined Modality Therapy; Cyclosporine; Cystitis; Cytarabine; Cytomegalovirus Infections; DNA, Neoplasm; Female; Foscarnet; Ganciclovir; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Histocompatibility; Humans; Hydroxyurea; Immunosuppressive Agents; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Methotrexate; Mitoxantrone; Neoplasms, Second Primary; Prednisolone; Prostaglandins; Remission Induction; Topotecan; Transplantation Conditioning; Transplantation, Homologous; Vidarabine; Whole-Body Irradiation

2001
[Acute myelogenous leukemia associated with severe esophageal stricture after chemotherapy].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2002, Volume: 43, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Esophageal Stenosis; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute

2002
Acute myelogenous leukemia: advances and limitations of treatment.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2002, Volume: 93, Issue:3

    Topics: Adult; Aminoglycosides; Anthracyclines; Anti-Bacterial Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Benzamides; Case-Control Studies; Cytarabine; Fatal Outcome; Gemtuzumab; Gingiva; Hematopoietic Stem Cell Transplantation; Humans; Imatinib Mesylate; Immunosuppressive Agents; Immunotoxins; Leukemia, Myeloid, Acute; Leukemic Infiltration; Male; Piperazines; Pyrimidines; Remission Induction; Sialic Acid Binding Ig-like Lectin 3

2002
Consequences of acute myelogenous leukemia in early pregnancy.
    Cancer, 1977, Volume: 40, Issue:3

    Topics: Abortion, Therapeutic; Antineoplastic Agents; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Infant Mortality; Infant, Newborn; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Pregnancy; Pregnancy Complications, Hematologic; Pregnancy Trimester, First; Pregnancy Trimester, Second; Risk; Teratogens; Thioguanine; Vincristine

1977
Current concepts of leukemia and results of recent treatment programs.
    Transplantation proceedings, 1978, Volume: 10, Issue:1

    Topics: Cell Transformation, Neoplastic; Clone Cells; Cytarabine; Hematopoiesis; Hematopoietic Stem Cells; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute

1978
Approaches to the treatment of acute leukemia and lymphoma in adults.
    Seminars in hematology, 1978, Volume: 15, Issue:3

    Topics: Acute Disease; Adult; Animals; BCG Vaccine; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Environment, Controlled; Humans; Immunotherapy; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma; Mice; Prednisone; Vincristine

1978
Advances in the treatment of acute myelogenous leukemia.
    The New England journal of medicine, 1979, May-24, Volume: 300, Issue:21

    Topics: Antineoplastic Agents; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Drug Therapy, Combination; Hemorrhage; Humans; Immunotherapy; Infections; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukemia, Radiation-Induced; Meningeal Neoplasms; Preleukemia; Prognosis; Remission, Spontaneous; Transplantation, Homologous

1979
Early consolidation chemotherapy for adults with acute leukemia in remission.
    Medical and pediatric oncology, 1976, Volume: 2, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Anti-Bacterial Agents; Antineoplastic Agents; Bacterial Infections; Cytarabine; Enterocolitis, Pseudomembranous; Female; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Necrosis; Prednisone; Remission, Spontaneous; Vincristine

1976
1-Beta-arabinofuranosylcytosine in therapy of leukemia: preclinical and clinical overview.
    Pharmacology & therapeutics, 1992, Volume: 56, Issue:3

    Topics: Animals; Clinical Trials as Topic; Cytarabine; Drug Screening Assays, Antitumor; Humans; Leukemia, Myeloid, Acute

1992
Hematopoietins in combination with 1-beta-D-arabinofuranosylcytosine: a possible strategy for improved treatment of myeloid disorders.
    Seminars in oncology, 1992, Volume: 19, Issue:2 Suppl 4

    Topics: Acute Disease; Antineoplastic Agents; Cytarabine; Drug Synergism; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Cell Growth Factors; Humans; Interleukin-3; Leukemia, Myeloid; Leukemia, Myeloid, Acute; S Phase

1992
High-dose cytosine arabinoside for the treatment of acute myeloid leukemia. Studies of the North American Marrow Transplant Group.
    Leukemia, 1992, Volume: 6 Suppl 4

    Topics: Cytarabine; Humans; Leukemia, Myeloid, Acute

1992
Aggressive chemotherapy for acute leukemia relapsed after bone marrow transplantation: a second chance?
    Acta haematologica, 1992, Volume: 87, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Chemotherapy, Adjuvant; Cytarabine; Daunorubicin; Humans; Idarubicin; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Recurrence; Time Factors; Vincristine

1992
Treatment of adult acute leukemia.
    Clinical pharmacy, 1992, Volume: 11, Issue:9

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prevalence; Prognosis; Remission Induction; United States

1992
Improving the "quality of remission induction" therapy: a necessary step for increasing the cure rate in acute myelogenous leukemia.
    Cancer investigation, 1992, Volume: 10, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Leukemia, Myeloid, Acute; Remission Induction

1992
Idarubicin: an anthracycline antineoplastic agent.
    Clinical pharmacy, 1992, Volume: 11, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biological Availability; Breast Neoplasms; Cytarabine; Drug Labeling; Humans; Idarubicin; Leukemia, Myeloid, Acute; Lung Neoplasms; Lymphoma; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma

1992
New drugs in acute myelogenous leukemia: a review.
    Journal of clinical pharmacology, 1992, Volume: 32, Issue:4

    Topics: Amsacrine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Evaluation; Humans; Idarubicin; Isomerism; Leukemia, Myeloid, Acute; Mitoxantrone; Remission Induction; Survival Rate; Tretinoin

1992
Evolution of treatment for acute myelogenous leukemia and myelodysplastic syndrome at M.D. Anderson Cancer Center 1985-1991.
    Leukemia, 1992, Volume: 6 Suppl 2

    Topics: Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Humans; Idarubicin; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Vidarabine

1992
Cellular and pharmacologic aspects of drug resistance in acute myeloid leukemia.
    Current opinion in oncology, 1991, Volume: 3, Issue:1

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cytarabine; Daunorubicin; DNA, Neoplasm; Drug Resistance; Gene Amplification; Humans; Leukemia, Myeloid, Acute; Membrane Glycoproteins; Neoplastic Stem Cells; Retrospective Studies

1991
To overcome pharmacologic and cytokinetic resistance to cytarabine in the treatment of acute myelogenous leukemia by using recombinant interleukin-3?
    Seminars in hematology, 1991, Volume: 28, Issue:3 Suppl 4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Cell Differentiation; Cytarabine; Drug Resistance; Humans; Interleukin-3; Leukemia, Myeloid, Acute; Recombinant Proteins

1991
CSFs in combination with cytosine arabinoside, an inhibitor of DNA synthesis: potential strategies for the treatment of myeloid disorders.
    Biotechnology therapeutics, 1991, Volume: 2, Issue:3-4

    Topics: Cell Differentiation; Colony-Stimulating Factors; Cytarabine; DNA, Neoplasm; Drug Synergism; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; In Vitro Techniques; Interleukin-3; Leukemia, Myeloid, Acute

1991
Gelatinous transformation of marrow in a case of acute myelogenous leukemia post-chemotherapy.
    American journal of hematology, 1991, Volume: 38, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Atrophy; Biopsy; Bone Marrow; Cytarabine; Daunorubicin; Female; Humans; Hyaluronic Acid; Leukemia, Myeloid, Acute; Middle Aged

1991
[Therapeutic possibilities in the treatment of the myelodysplasia syndrome].
    Orvosi hetilap, 1991, May-12, Volume: 132, Issue:19

    Topics: Age Factors; Anemia, Sideroblastic; Antineoplastic Agents; Blastomeres; Bone Marrow Transplantation; Cytarabine; Hematopoiesis; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Myelodysplastic Syndromes

1991
Cytosine arabinoside in the treatment of acute myeloid leukemia: the role and place of high-dose regimens.
    Annals of hematology, 1991, Volume: 62, Issue:4

    Topics: Cytarabine; Drug Resistance; Humans; Leukemia, Myeloid, Acute; Recurrence

1991
Pharmacologically directed design of leukemia therapy.
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cytarabine; Drug Evaluation; Humans; Leukemia; Leukemia, Myeloid, Acute; Mitoxantrone

1990
Differentiating agents in the treatment of leukemia.
    Leukemia research, 1990, Volume: 14, Issue:8

    Topics: Cell Differentiation; Cytarabine; Humans; Interferon Type I; Leukemia; Leukemia, Hairy Cell; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Myelodysplastic Syndromes; Tretinoin

1990
Differentiating agents in the treatment of leukemia and myelodysplastic syndromes.
    Leukemia research, 1990, Volume: 14, Issue:8

    Topics: Cell Differentiation; Cell Division; Cytarabine; Humans; Interferon Type I; Leukemia; Leukemia, Hairy Cell; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Myelodysplastic Syndromes; Tretinoin

1990
Cure of acute myelocytic leukemia in adults: a reality.
    Leukemia, 1990, Volume: 4, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Middle Aged; Randomized Controlled Trials as Topic; Remission Induction

1990
Rationales for a pharmacologically optimized treatment of acute nonlymphocytic leukemia with cytosine arabinoside.
    Leukemia, 1990, Volume: 4, Issue:11

    Topics: Arabinofuranosylcytosine Triphosphate; Biological Transport; Cytarabine; Deamination; Drug Administration Schedule; Drug Resistance; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Phosphorylation; Recurrence

1990
Eccrine squamous syringometaplasia. A cutaneous sweat gland reaction in the histologic spectrum of 'chemotherapy-associated eccrine hidradenitis' and 'neutrophilic eccrine hidradenitis'.
    Archives of dermatology, 1990, Volume: 126, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Atrophy; Cytarabine; Eccrine Glands; Humans; Inflammation; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Sweat Glands

1990
Treatment of acute myelogenous leukemia in the elderly.
    Seminars in oncology, 1989, Volume: 16, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Immunotherapy; Leukemia, Myeloid, Acute; Remission Induction

1989
Treatment of relapsed and refractory acute myeloid leukemia in adults.
    Bone marrow transplantation, 1989, Volume: 4 Suppl 1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Resistance; Etoposide; Humans; Idarubicin; Leukemia, Myeloid, Acute; Mitoxantrone; Remission Induction

1989
High dose therapy and autologous bone marrow transplant (ABMT) in acute leukemia: is purging necessary?
    Bone marrow transplantation, 1989, Volume: 4 Suppl 1

    Topics: Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Humans; Leukemia, Myeloid, Acute; Neoplastic Stem Cells; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Preoperative Care; Transplantation, Autologous; Whole-Body Irradiation

1989
High dose cytarabine in acute myelogenous leukemia.
    Bone marrow transplantation, 1989, Volume: 4 Suppl 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Humans; Leukemia, Myeloid, Acute; Remission Induction

1989
Etoposide: fifteen years experience.
    Bone marrow transplantation, 1989, Volume: 4 Suppl 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Evaluation; Etoposide; Hodgkin Disease; Humans; Leukemia; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Lomustine; Melphalan; Mitoxantrone

1989
[Progress in the treatment of acute myelogenous leukemia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:5

    Topics: Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Cytarabine; Daunorubicin; Heart; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Middle Aged; Prednisolone; Prognosis; Remission Induction; Vincristine

1989
High dose cytosine arabinoside in the treatment of adult acute myelogenous leukaemia.
    Bone marrow transplantation, 1989, Volume: 4 Suppl 3

    Topics: Adult; Clinical Trials as Topic; Cytarabine; Humans; Leukemia, Myeloid, Acute

1989
Mitoxantrone in the treatment of refractory and relapsed non-lymphoblastic acute leukaemia.
    Bone marrow transplantation, 1989, Volume: 4 Suppl 3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Leukemia, Myeloid, Acute; Mitoxantrone

1989
[Acute pericarditis caused by daunorubicin in acute myelocytic leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1988, Volume: 29, Issue:6

    Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Pericarditis

1988
Differentiation in acute myeloid leukemia and myelodysplastic disorders. Is differentiation-induction therapy possible?
    Australian and New Zealand journal of medicine, 1988, Volume: 18, Issue:5

    Topics: Cell Differentiation; Cytarabine; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Tretinoin

1988
High-dose cytosine arabinoside: pharmacological and clinical aspects.
    Blut, 1988, Volume: 56, Issue:1

    Topics: Animals; Cytarabine; Drug Administration Schedule; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute

1988
High dose cytarabine: a review.
    Leukemia, 1988, Volume: 2, Issue:5

    Topics: Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cytarabine; Daunorubicin; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Pancytopenia

1988
Low dose cytosine arabinoside in myelodysplasia and acute myelogenous leukemia: a review.
    Leukemia, 1987, Volume: 1, Issue:8

    Topics: Age Factors; Cytarabine; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes

1987
[Clinical observations of 30 patients with acute promyelocytic leukemia].
    Gaoxiong yi xue ke xue za zhi = The Kaohsiung journal of medical sciences, 1986, Volume: 2, Issue:10

    Topics: Adolescent; Adult; Age Factors; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disseminated Intravascular Coagulation; Female; Heparin; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Naphthacenes; Remission Induction

1986
Treatment of patients with myelodysplastic syndromes: a review.
    Scandinavian journal of haematology. Supplementum, 1986, Volume: 45

    Topics: Adolescent; Adult; Age Factors; Bone Marrow Transplantation; Cell Differentiation; Child, Preschool; Cytarabine; Drug Therapy, Combination; Female; Hematopoiesis; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Tretinoin; Vitamin D

1986
Amsacrine: a review.
    Leukemia research, 1986, Volume: 10, Issue:11

    Topics: Amsacrine; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Evaluation; Drug Resistance; Humans; Leukemia, Experimental; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma

1986
[Ultrahigh-dosage cytostatics--their possible use in acute leukemias?].
    Deutsche medizinische Wochenschrift (1946), 1987, Jan-09, Volume: 112, Issue:2

    Topics: Antineoplastic Agents; Cyclophosphamide; Cytarabine; Dose-Response Relationship, Drug; Etoposide; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Melphalan; Recurrence

1987
The treatment of myelodysplastic syndromes.
    Clinics in haematology, 1986, Volume: 15, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Blood Transfusion; Bone Marrow Transplantation; Cytarabine; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Middle Aged; Myelodysplastic Syndromes; Preleukemia; Prognosis

1986
Leukemic cell maturation.
    Archives of pathology & laboratory medicine, 1985, Volume: 109, Issue:4

    Topics: Cell Differentiation; Cell Line; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Dimethyl Sulfoxide; Genotype; Hematopoietic Stem Cells; Humans; Leukemia; Leukemia, Myeloid, Acute; Neoplastic Stem Cells; Neutrophils; Oncogenes; Phenotype; Tetradecanoylphorbol Acetate; Vitamin A

1985
Acute nonlymphocytic leukemia.
    Pediatric clinics of North America, 1985, Volume: 32, Issue:3

    Topics: Adolescent; Adult; Antigens, Surface; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Chromosome Aberrations; Cytarabine; Doxorubicin; Hematopoietic Stem Cells; Humans; Leukemia; Leukemia, Myeloid, Acute; Nervous System Neoplasms; Prednisolone; Prognosis; Recurrence; Risk; Vincristine

1985
Biochemical and cellular pharmacology of cytosine arabinoside.
    Seminars in oncology, 1985, Volume: 12, Issue:2 Suppl 3

    Topics: Animals; Aphidicolin; Arabinofuranosylcytosine Triphosphate; Binding, Competitive; Cell Line; Cell Survival; Centrifugation, Density Gradient; Cytarabine; Diterpenes; DNA; DNA Repair; DNA Replication; Fibroblasts; Granulocytes; Humans; Kinetics; Leukemia L1210; Leukemia, Myeloid, Acute; Nucleic Acid Synthesis Inhibitors; Templates, Genetic; Vidarabine

1985
Acute leukemia in adults.
    Seminars in hematology, 1974, Volume: 11, Issue:1

    Topics: Adult; Alkaline Phosphatase; BCG Vaccine; Blood Transfusion; Bone Marrow Examination; Central Nervous System Diseases; Cytarabine; Daunorubicin; Diagnosis, Differential; Drug Combinations; Drug Therapy, Combination; Esterases; Humans; Immunotherapy; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphocyte Transfusion; Meningitis; Microscopy, Electron; Neutrophils; Staining and Labeling; Subarachnoid Hemorrhage; Thioguanine

1974
Treatment of acute leukemia.
    Pediatric clinics of North America, 1972, Volume: 19, Issue:4

    Topics: Asparaginase; Bacterial Infections; Central Nervous System Diseases; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Synergism; Hemorrhage; Humans; Immunotherapy; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Mitosis; Neoplasms, Nerve Tissue; Prednisone; Remission, Spontaneous; Testicular Neoplasms; Uric Acid; Vincristine

1972
[Progress in the chemotherapy of acute leukemias].
    Deutsche medizinische Wochenschrift (1946), 1972, Oct-06, Volume: 97, Issue:40

    Topics: Adult; Age Factors; Antineoplastic Agents; Child; Cyclophosphamide; Cytarabine; Follow-Up Studies; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Prednisone; Time Factors; Vincristine

1972
[Treatment of acute leukemia. Controlled clinical trials and experimental data with a view to a more rational administration of anti-leukemic drugs].
    Revue medicale de Liege, 1973, Jun-15, Volume: 28, Issue:12

    Topics: Clinical Trials as Topic; Cytarabine; Daunorubicin; DNA, Neoplasm; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate; Prednisolone; Vincristine

1973
[Treatment of acute leukemias].
    Terapevticheskii arkhiv, 1973, Volume: 45, Issue:9

    Topics: Acute Disease; Adult; Age Factors; Antineoplastic Agents; Asparaginase; Child; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methods; Methotrexate; Prednisolone; Recurrence; Remission, Spontaneous; Vincristine

1973
Treatment of acute granulocytic leukemias.
    Annual review of medicine, 1974, Volume: 25

    Topics: Adult; Age Factors; Antineoplastic Agents; Blood Cell Count; Blood Platelets; Bone Marrow Examination; Child; Cytarabine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Heart; Hemorrhage; Humans; Hydrazones; Injections, Intravenous; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocyte Count

1974
Present treatment of acute leukemias.
    Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society, 1973, Volume: 36, Issue:5

    Topics: Asparaginase; Blood Transfusion; Cytarabine; Daunorubicin; Humans; Immunotherapy; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocytes; Meninges; Mercaptopurine; Methotrexate; Prednisone; Remission, Spontaneous

1973
[Lysozyme and leukemia. Diagnostic, prognostic and pathogenic significance of lysozyme measurements].
    Ugeskrift for laeger, 1974, Oct-28, Volume: 136, Issue:44

    Topics: Cytarabine; Evaluation Studies as Topic; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Methods; Muramidase; Neutrophils; Thioguanine

1974
[Treatment of acute leukemias].
    Les Cahiers du College de medecine des hopitaux de Paris, 1968, May-15, Volume: 9, Issue:5

    Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Antineoplastic Agents; Child; Child, Preschool; Cytarabine; Female; Humans; Infant; Infant, Newborn; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Prednisone; Vincristine

1968
[New principles of treatment in acute leukemia].
    Ugeskrift for laeger, 1970, Apr-30, Volume: 132, Issue:18

    Topics: Adolescent; Adult; Antineoplastic Agents; Central Nervous System Diseases; Child; Cyclophosphamide; Cytarabine; Female; Guanidines; Humans; Hydroxyurea; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukopenia; Male; Mercaptopurine; Methotrexate; Middle Aged; Nitroso Compounds; Prednisone; Thrombocytopenia; Urea; Uric Acid; Vincristine

1970
Kinetics of normal and leukemic leukocyte populations and relevance to chemotherapy.
    Cancer research, 1970, Volume: 30, Issue:6

    Topics: Alkylating Agents; Animals; Antineoplastic Agents; Bone Marrow Cells; Cell Division; Cytarabine; Hematopoietic System; Humans; Kinetics; Leukemia; Leukemia L1210; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Lymphocytes; Mice; Neoplasm Transplantation; Thymidine; Time Factors; Tritium

1970
Changing concepts of treatment in acute leukemia.
    The Medical clinics of North America, 1971, Volume: 55, Issue:3

    Topics: Acute Disease; Animals; Antineoplastic Agents; Asparaginase; Cell Differentiation; Cell Division; Cytarabine; DNA; Erythropoiesis; Hematopoiesis; Humans; Immunosuppressive Agents; Kinetics; Leukemia; Leukemia, Experimental; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mice; Mitosis; Models, Biological; Oncogenic Viruses; Prednisone; Remission, Spontaneous; Time Factors

1971
The treatment of acute myeloblastic leukaemia.
    British journal of haematology, 1971, Volume: 20, Issue:6

    Topics: Child; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Synergism; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Meningitis; Mercaptopurine; Prednisone; Remission, Spontaneous; Thioguanine; Vincristine

1971
The chemotherapy of human and animal acute leukemia.
    Cancer chemotherapy reports, 1971, Volume: 55, Issue:4

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Asparaginase; Azaserine; Cell Division; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Disease Models, Animal; Drug Combinations; Humans; Kinetics; Leukemia L1210; Leukemia, Experimental; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Neoplasms; Prednisone; Remission, Spontaneous; RNA, Neoplasm; Vincristine

1971
Combination chemotherapy in malignant diseases.
    Journal of the Royal College of Physicians of London, 1971, Volume: 5, Issue:2

    Topics: Adult; Antineoplastic Agents; Asparaginase; Carmustine; Child; Cyclophosphamide; Cytarabine; Cytosine; Daunorubicin; Drug Therapy, Combination; Hodgkin Disease; Humans; Immunotherapy; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma; Male; Mechlorethamine; Mercaptopurine; Methotrexate; Nitrogen Mustard Compounds; Prednisolone; Prednisone; Procarbazine; Remission, Spontaneous; Vincristine

1971

Trials

823 trial(s) available for cytarabine and Acute Myelogenous Leukemia

ArticleYear
Omacetaxine added to a standard acute myeloid leukaemia chemotherapy regimen reduces cellular FLIP levels, markedly increasing the incidence of eccrine hidradenitis.
    British journal of haematology, 2021, Volume: 195, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; CASP8 and FADD-Like Apoptosis Regulating Protein; Cyclophosphamide; Cytarabine; Daunorubicin; Down-Regulation; Drug Eruptions; Hidradenitis; Homoharringtonine; Humans; Incidence; Leukemia, Myeloid, Acute; Mercaptopurine; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Neutrophils; Protein Kinase Inhibitors; Sweat Glands

2021
Phase 1/2 study of uproleselan added to chemotherapy in patients with relapsed or refractory acute myeloid leukemia.
    Blood, 2022, 02-24, Volume: 139, Issue:8

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Etoposide; Female; Glycolipids; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Survival Rate

2022
Randomized evaluation of quizartinib and low-dose ara-C vs low-dose ara-C in older acute myeloid leukemia patients.
    Blood advances, 2021, 12-28, Volume: 5, Issue:24

    Topics: Aged; Benzothiazoles; Cytarabine; Humans; Leukemia, Myeloid, Acute; Phenylurea Compounds

2021
Real-world experience of CPX-351 as first-line treatment for patients with acute myeloid leukemia.
    Blood cancer journal, 2021, 10-04, Volume: 11, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Allografts; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm, Residual; Survival Rate

2021
Optimization of idarubicin and cytarabine induction regimen with homoharringtonine for newly diagnosed acute myeloid leukemia patients based on the peripheral blast clearance rate: A single-arm, phase 2 trial (RJ-AML 2014).
    American journal of hematology, 2022, 01-01, Volume: 97, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Homoharringtonine; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Treatment Outcome

2022
A prospective biomarker analysis of alvocidib followed by cytarabine and mitoxantrone in MCL-1-dependent relapsed/refractory acute myeloid leukemia.
    Blood cancer journal, 2021, 10-30, Volume: 11, Issue:10

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cytarabine; Female; Flavonoids; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Myeloid Cell Leukemia Sequence 1 Protein; Piperidines

2021
Bortezomib is significantly beneficial for de novo pediatric AML patients with low phosphorylation of the NF-κB subunit RelA.
    Proteomics. Clinical applications, 2022, Volume: 16, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bortezomib; Child; Cytarabine; Humans; Leukemia, Myeloid, Acute; Neoplasm Recurrence, Local; NF-kappa B; Phosphorylation; Transcription Factor RelA

2022
Phase II Trial of Pembrolizumab after High-Dose Cytarabine in Relapsed/Refractory Acute Myeloid Leukemia.
    Blood cancer discovery, 2021, Volume: 2, Issue:6

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; CD8-Positive T-Lymphocytes; Cytarabine; Drug Resistance, Neoplasm; Humans; Leukemia, Myeloid, Acute

2021
Treatment intensification with FLAG-Ida may improve disease control in younger patients with secondary acute myeloid leukaemia: long-term follow up of the MRC AML15 trial.
    British journal of haematology, 2022, Volume: 196, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Middle Aged; Neoplasm Recurrence, Local; Neoplasms, Second Primary; Remission Induction; Vidarabine

2022
Decitabine and vorinostat with FLAG chemotherapy in pediatric relapsed/refractory AML: Report from the therapeutic advances in childhood leukemia and lymphoma (TACL) consortium.
    American journal of hematology, 2022, Volume: 97, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Decitabine; Humans; Leukemia, Myeloid, Acute; Lymphoma; Vorinostat

2022
Cladribine-based debulking chemotherapy sequential with reduced intensity regimen and post-transplantation maintenance for refractory myeloid leukemia: a prospective phase II clinical trial.
    Bone marrow transplantation, 2022, Volume: 57, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cytarabine; Cytoreduction Surgical Procedures; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Prospective Studies; Remission Induction; Transplantation Conditioning

2022
Phase II trial of cytarabine and mitoxantrone with devimistat in acute myeloid leukemia.
    Nature communications, 2022, 03-30, Volume: 13, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Caprylates; Cytarabine; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Sulfides; Treatment Outcome

2022
A randomised comparison of FLAG-Ida versus daunorubicin combined with clofarabine in relapsed or refractory acute myeloid leukaemia: Results from the UK NCRI AML17 trial.
    British journal of haematology, 2022, Volume: 198, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chronic Disease; Clofarabine; Cytarabine; Daunorubicin; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; United Kingdom; Vidarabine

2022
Idasanutlin plus cytarabine in relapsed or refractory acute myeloid leukemia: results of the MIRROS trial.
    Blood advances, 2022, 07-26, Volume: 6, Issue:14

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Leukemia, Myeloid, Acute; para-Aminobenzoates; Pyrrolidines

2022
Efficacy of conventional-dose cytarabine, idarubicin and thioguanine versus intermediate-dose cytarabine and idarubicin in the induction treatment of acute myeloid leukemia: Long-term results of the prospective randomized nationwide AML-2003 study by the
    European journal of haematology, 2022, Volume: 109, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Finland; Humans; Idarubicin; Leukemia, Myeloid, Acute; Middle Aged; Neoplasm, Residual; Prospective Studies; Remission Induction; Thioguanine

2022
Phase II Study of Venetoclax Added to Cladribine Plus Low-Dose Cytarabine Alternating With 5-Azacitidine in Older Patients With Newly Diagnosed Acute Myeloid Leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2022, 11-20, Volume: 40, Issue:33

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bridged Bicyclo Compounds, Heterocyclic; Cladribine; Cytarabine; Humans; Leukemia, Myeloid, Acute; Middle Aged

2022
Enasidenib vs conventional care in older patients with late-stage mutant-IDH2 relapsed/refractory AML: a randomized phase 3 trial.
    Blood, 2023, 01-12, Volume: 141, Issue:2

    Topics: Aged; Cytarabine; Humans; Isocitrate Dehydrogenase; Leukemia, Myeloid, Acute; Mutation

2023
Real-world experience in treating pediatric relapsed/refractory or therapy-related myeloid malignancies with decitabine, vorinostat, and FLAG therapy based on a phase 1 study run by the TACL consortium.
    Pediatric blood & cancer, 2022, Volume: 69, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Decitabine; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Neoplasm Recurrence, Local; Vidarabine; Vorinostat

2022
Addition of the nuclear export inhibitor selinexor to standard intensive treatment for elderly patients with acute myeloid leukemia and high risk myelodysplastic syndrome.
    Leukemia, 2022, Volume: 36, Issue:9

    Topics: Active Transport, Cell Nucleus; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Hydrazines; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Triazoles

2022
Retrospective comparison of survival and responses to Fludarabine, Cytarabine, GCSF (FLAG) in combination with gemtuzumab ozogamicin (GO) or Idarubicin (IDA) in patients with newly diagnosed core binding factor (CBF) acute myelogenous leukemia: MD Anderso
    American journal of hematology, 2022, Volume: 97, Issue:11

    Topics: Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Core Binding Factors; Cytarabine; Gemtuzumab; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Prospective Studies; Retrospective Studies; Vidarabine

2022
Two-drug versus three-drug induction chemotherapy in pediatric acute myeloid leukemia: a randomized controlled trial.
    Blood cancer journal, 2022, 09-06, Volume: 12, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Daunorubicin; Female; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Remission Induction

2022
Efficacy and safety of CPX-351 versus 7 + 3 chemotherapy by European LeukemiaNet 2017 risk subgroups in older adults with newly diagnosed, high-risk/secondary AML: post hoc analysis of a randomized, phase 3 trial.
    Journal of hematology & oncology, 2022, 10-26, Volume: 15, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Neoplasms, Second Primary

2022
Venetoclax combined with low dose cytarabine compared to standard of care intensive chemotherapy for the treatment of favourable risk adult acute myeloid leukaemia (VICTOR): Study protocol for an international, open-label, multicentre, molecularly-guided
    BMC cancer, 2022, Nov-14, Volume: 22, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bayes Theorem; Clinical Trials, Phase II as Topic; Cytarabine; Humans; Leukemia, Myeloid, Acute; Multicenter Studies as Topic; Neoplasm Recurrence, Local; Nuclear Proteins; Quality of Life; Standard of Care

2022
A randomized phase 2 trial of nintedanib and low-dose cytarabine in elderly patients with acute myeloid leukemia ineligible for intensive chemotherapy.
    Annals of hematology, 2023, Volume: 102, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Indoles; Leukemia, Myeloid, Acute

2023
A randomised evaluation of low-dose Ara-C plus pegylated recombinant arginase BCT-100 versus low dose Ara-C in older unfit patients with acute myeloid leukaemia: Results from the LI-1 trial.
    British journal of haematology, 2023, Volume: 200, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Arginase; Cytarabine; Humans; Leukemia, Myeloid, Acute; Middle Aged; Polyethylene Glycols

2023
A phase II study of combination daunorubicin, cytarabine (Ara-c), and nilotinib (TAsigna) (DATA) in patients newly diagnosed with acute myeloid leukemia with KIT expression.
    American journal of hematology, 2023, Volume: 98, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Middle Aged; Remission Induction

2023
A phase II study of chidamide, cytarabine, aclarubicin, granulocyte colony-stimulating factor, and donor lymphocyte infusion for relapsed acute myeloid leukemia and myelodysplastic syndrome after allogeneic hematopoietic stem cell transplantation.
    Medical oncology (Northwood, London, England), 2023, Jan-10, Volume: 40, Issue:2

    Topics: Aclarubicin; Adult; Cytarabine; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Lymphocytes; Myelodysplastic Syndromes; Recurrence

2023
Results from a phase I study of continuous infusion cladribine, high-dose cytarabine, and mitoxantrone for relapsed/refractory high-grade myeloid neoplasms.
    Leukemia & lymphoma, 2023, Volume: 64, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cytarabine; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Neoplasm Recurrence, Local

2023
Molecular targeting of the UDP-glucuronosyltransferase enzymes in high-eukaryotic translation initiation factor 4E refractory/relapsed acute myeloid leukemia patients: a randomized phase II trial of vismodegib, ribavirin with or without decitabine.
    Haematologica, 2023, 11-01, Volume: 108, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Decitabine; Eukaryotic Initiation Factor-4E; Glucuronosyltransferase; Hedgehog Proteins; Humans; Leukemia, Myeloid, Acute; Molecular Targeted Therapy; Ribavirin; Uridine Diphosphate; Zinc Finger Protein GLI1

2023
Venetoclax plus low-dose cytarabine in patients with newly diagnosed acute myeloid leukemia ineligible for intensive chemotherapy: an expanded access study in Japan.
    Japanese journal of clinical oncology, 2023, Jun-29, Volume: 53, Issue:7

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Japan; Leukemia, Myeloid, Acute; Middle Aged; Tumor Lysis Syndrome

2023
Single-center phase 2 study of PD-1 inhibitor combined with DNA hypomethylation agent + CAG regimen in patients with relapsed/refractory acute myeloid leukemia.
    Cancer immunology, immunotherapy : CII, 2023, Volume: 72, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Decitabine; Humans; Immune Checkpoint Inhibitors; Leukemia, Myeloid, Acute; Treatment Outcome

2023
A randomized comparison of CPX-351 and FLAG-Ida in adverse karyotype AML and high-risk MDS: the UK NCRI AML19 trial.
    Blood advances, 2023, 08-22, Volume: 7, Issue:16

    Topics: Adult; Aged; Cytarabine; Daunorubicin; Humans; Karyotype; Leukemia, Myeloid, Acute; Middle Aged; Myelodysplastic Syndromes; United Kingdom

2023
Intensive chemotherapy with or without gemtuzumab ozogamicin in patients with NPM1-mutated acute myeloid leukaemia (AMLSG 09-09): a randomised, open-label, multicentre, phase 3 trial.
    The Lancet. Haematology, 2023, Volume: 10, Issue:7

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Recurrence, Local; Nuclear Proteins; Treatment Outcome; Tretinoin; Young Adult

2023
Guadecitabine vs treatment choice in newly diagnosed acute myeloid leukemia: a global phase 3 randomized study.
    Blood advances, 2023, 09-12, Volume: 7, Issue:17

    Topics: Azacitidine; Cytarabine; Humans; Leukemia, Myeloid, Acute; Treatment Outcome

2023
Phase 1/2 study of sorafenib added to cladribine, high-dose cytarabine, G-CSF, and mitoxantrone in untreated AML.
    Blood advances, 2023, 09-12, Volume: 7, Issue:17

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Sorafenib

2023
A Phase I study of Milademetan (DS3032b) in combination with low dose cytarabine with or without venetoclax in acute myeloid leukemia: Clinical safety, efficacy, and correlative analysis.
    Blood cancer journal, 2023, 06-29, Volume: 13, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Cytarabine; Humans; Leukemia, Myeloid, Acute; Middle Aged; Myeloid Cell Leukemia Sequence 1 Protein; Proteomics; Tumor Suppressor Protein p53; Young Adult

2023
Glasdegib plus intensive or non-intensive chemotherapy for untreated acute myeloid leukemia: results from the randomized, phase 3 BRIGHT AML 1019 trial.
    Leukemia, 2023, Volume: 37, Issue:10

    Topics: Anemia; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Nausea

2023
Phase II study of cladribine, idarubicin, and ara-C (CLIA) with or without sorafenib as initial therapy for patients with acute myeloid leukemia.
    American journal of hematology, 2023, Volume: 98, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cytarabine; Humans; Idarubicin; Leukemia, Myeloid, Acute; Middle Aged; Remission Induction; Sorafenib

2023
Low-dose decitabine priming with intermediate-dose cytarabine followed by umbilical cord blood infusion as consolidation therapy for elderly patients with acute myeloid leukemia: a phase II single-arm study.
    BMC cancer, 2019, Aug-20, Volume: 19, Issue:1

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Blood Transfusion; Consolidation Chemotherapy; Cytarabine; Decitabine; Disease-Free Survival; Female; Fetal Blood; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prospective Studies; Survival Rate

2019
Glasdegib in the treatment of acute myeloid leukemia.
    Future oncology (London, England), 2019, Volume: 15, Issue:28

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Cytarabine; Drug Evaluation; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Phenylurea Compounds; Prognosis; Survival Rate

2019
Phase I Clinical Trial of Selinexor in Combination with Daunorubicin and Cytarabine in Previously Untreated Poor-Risk Acute Myeloid Leukemia.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2020, 01-01, Volume: 26, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Hydrazines; Leukemia, Myeloid, Acute; Male; Maximum Tolerated Dose; Middle Aged; Patient Safety; Survival Rate; Tissue Distribution; Treatment Outcome; Triazoles

2020
Early induction intensification with cladribine, cytarabine, and mitoxantrone (CLAM) in AML patients treated with the DAC induction regimen: a prospective, non-randomized, phase II study of the Polish Adult Leukemia Group (PALG).
    Leukemia & lymphoma, 2020, Volume: 61, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cytarabine; Humans; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Poland; Prospective Studies; Remission Induction

2020
Two-dimensional speckle-tracking strain detects subclinical cardiotoxicity in older patients treated for acute myeloid leukemia.
    Echocardiography (Mount Kisco, N.Y.), 2019, Volume: 36, Issue:11

    Topics: Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Cardiotoxicity; Clofarabine; Cytarabine; Daunorubicin; Echocardiography; Female; Follow-Up Studies; Heart Ventricles; Humans; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Retrospective Studies; Stroke Volume; Ventricular Dysfunction, Left; Ventricular Function, Left

2019
Every-other-day palonosetron plus aprepitant for prevention of emesis following induction chemotherapy for acute myeloid leukemia: A randomized, controlled study from the "Rete Ematologica Pugliese".
    Cancer medicine, 2020, Volume: 9, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anthracyclines; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Cytarabine; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Nausea; Palonosetron; Treatment Failure; Vomiting; Young Adult

2020
Selinexor combined with cladribine, cytarabine, and filgrastim in relapsed or refractory acute myeloid leukemia.
    Haematologica, 2020, Volume: 105, Issue:8

    Topics: Adult; Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cytarabine; Female; Filgrastim; Humans; Hydrazines; Leukemia, Myeloid, Acute; Male; Mice, Inbred C57BL; Middle Aged; Remission Induction; Treatment Outcome; Triazoles; Young Adult

2020
Consolidation outcomes in CPX-351 versus cytarabine/daunorubicin-treated older patients with high-risk/secondary acute myeloid leukemia.
    Leukemia & lymphoma, 2020, Volume: 61, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Middle Aged

2020
BST-236, a novel cytarabine prodrug for patients with acute leukemia unfit for standard induction: a phase 1/2a study.
    Blood advances, 2019, 11-26, Volume: 3, Issue:22

    Topics: Adult; Aged; Aged, 80 and over; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prodrugs; Prognosis; Treatment Outcome

2019
Increased mitochondrial apoptotic priming with targeted therapy predicts clinical response to re-induction chemotherapy.
    American journal of hematology, 2020, Volume: 95, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cytarabine; Etoposide; Female; Humans; Induction Chemotherapy; Lenalidomide; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitochondria; Mitoxantrone

2020
Gemtuzumab Ozogamicin in
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2020, 02-20, Volume: 38, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Consolidation Chemotherapy; Cytarabine; Etoposide; Female; Gemtuzumab; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Nuclear Proteins; Nucleophosmin; Progression-Free Survival; Prospective Studies; Tretinoin; Young Adult

2020
A phase 1 study of the antibody-drug conjugate brentuximab vedotin with re-induction chemotherapy in patients with CD30-expressing relapsed/refractory acute myeloid leukemia.
    Cancer, 2020, 03-15, Volume: 126, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Brentuximab Vedotin; Cytarabine; Disease-Free Survival; Drug Administration Schedule; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Immunoconjugates; Induction Chemotherapy; Ki-1 Antigen; Leukemia, Myeloid, Acute; Male; Maximum Tolerated Dose; Middle Aged; Mitoxantrone; Recurrence; Young Adult

2020
Lenalidomide added to standard intensive treatment for older patients with AML and high-risk MDS.
    Leukemia, 2020, Volume: 34, Issue:7

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Follow-Up Studies; Humans; Induction Chemotherapy; Lenalidomide; Leukemia, Myeloid, Acute; Male; Myelodysplastic Syndromes; Prognosis; Remission Induction; Survival Rate

2020
A phase 1 study of azacitidine with high-dose cytarabine and mitoxantrone in high-risk acute myeloid leukemia.
    Blood advances, 2020, 02-25, Volume: 4, Issue:4

    Topics: Aged; Azacitidine; Cytarabine; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Nucleophosmin; Remission Induction

2020
Randomized phase 1 study of sequential ("primed") vs. concurrent decitabine in combination with cladribine, cytarabine, G-CSF, and mitoxantrone (CLAG-M) in adults with newly diagnosed or relapsed/refractory acute myeloid leukemia (AML) or other high-grade
    Leukemia & lymphoma, 2020, Volume: 61, Issue:7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cytarabine; Decitabine; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Treatment Outcome

2020
Combination of dasatinib with chemotherapy in previously untreated core binding factor acute myeloid leukemia: CALGB 10801.
    Blood advances, 2020, 02-25, Volume: 4, Issue:4

    Topics: Adult; Aged; Cytarabine; Dasatinib; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Remission Induction

2020
Outcomes of acute myeloid leukemia with myelodysplasia related changes depend on diagnostic criteria and therapy.
    American journal of hematology, 2020, Volume: 95, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Myelodysplastic Syndromes; Neoplasm Proteins; Sulfonamides; Survival Rate

2020
Microtransplantation in older patients with AML: A pilot study of safety, efficacy and immunologic effects.
    American journal of hematology, 2020, Volume: 95, Issue:6

    Topics: Aged; Allografts; Cytarabine; Female; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Pilot Projects; Risk Factors

2020
Venetoclax plus LDAC for newly diagnosed AML ineligible for intensive chemotherapy: a phase 3 randomized placebo-controlled trial.
    Blood, 2020, 06-11, Volume: 135, Issue:24

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Female; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Remission Induction; Sulfonamides; Treatment Outcome

2020
Safety, feasibility and preliminary efficacy of single agent combretastatin A1 diphosphate (OXi4503) in patients with relapsed or refractory acute myeloid leukemia or myelodysplastic syndromes.
    British journal of haematology, 2020, Volume: 189, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Diphosphates; Drug Resistance, Neoplasm; Drug Synergism; Feasibility Studies; Female; Fibrin Fibrinogen Degradation Products; Hemorrhage; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Prodrugs; Respiratory Distress Syndrome; Salvage Therapy; Stilbenes; Treatment Outcome; Young Adult

2020
Association of fludarabin, cytarabine, and fractioned gemtuzumab followed by hematopoietic stem cell transplantation for first-line refractory acute myeloid leukemia in children: A single-center experience.
    Pediatric blood & cancer, 2020, Volume: 67, Issue:6

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Combined Modality Therapy; Cytarabine; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Gemtuzumab; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Neoplasm Recurrence, Local; Prognosis; Retrospective Studies; Salvage Therapy; Survival Rate; Vidarabine

2020
Comparison of efficacy of HCAG and CAG re-induction chemotherapy in elderly low- and intermediate-risk group patients diagnosed with acute myeloid leukemia.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2021, Volume: 23, Issue:1

    Topics: Aclarubicin; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Female; Granulocyte Colony-Stimulating Factor; Homoharringtonine; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Progression-Free Survival; Remission Induction; Retreatment; Retrospective Studies; Risk Factors; Salvage Therapy; Single-Blind Method; Time Factors; Treatment Failure

2021
A Phase II study of selinexor plus cytarabine and idarubicin in patients with relapsed/refractory acute myeloid leukaemia.
    British journal of haematology, 2020, Volume: 190, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Gastrointestinal Diseases; Hematologic Diseases; Hematopoietic Stem Cell Transplantation; Humans; Hydrazines; Idarubicin; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Progression-Free Survival; Recurrence; Salvage Therapy; Triazoles

2020
Outpatient ADE (cytarabine, daunorubicin, and etoposide) is feasible and effective for the first relapse of pediatric acute myeloid leukemia: A prospective, phase II study.
    Pediatric blood & cancer, 2020, Volume: 67, Issue:9

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Prospective Studies; Recurrence; Survival Rate

2020
A quality-adjusted survival time without symptoms or toxicities analysis of glasdegib plus low-dose cytarabine versus low-dose cytarabine as initial therapy for acute myeloid leukemia in patients who are not considered candidates for intensive chemotherap
    Cancer, 2020, 10-01, Volume: 126, Issue:19

    Topics: Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Phenylurea Compounds; Survival Analysis

2020
Entospletinib in Combination with Induction Chemotherapy in Previously Untreated Acute Myeloid Leukemia: Response and Predictive Significance of
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2020, 11-15, Volume: 26, Issue:22

    Topics: Adult; Cytarabine; Daunorubicin; Female; Gene Expression Regulation, Neoplastic; Homeodomain Proteins; Humans; Indazoles; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Myeloid Ecotropic Viral Integration Site 1 Protein; Pyrazines; Syk Kinase

2020
Chidamide, decitabine, cytarabine, aclarubicin, and granulocyte colony-stimulating factor (CDCAG) in patients with relapsed/refractory acute myeloid leukemia: a single-arm, phase 1/2 study.
    Clinical epigenetics, 2020, 09-01, Volume: 12, Issue:1

    Topics: Aclarubicin; Adolescent; Adult; Aminopyridines; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Cytarabine; Decitabine; Disease-Free Survival; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Treatment Outcome; Young Adult

2020
An evaluation of overall survival in patients with newly diagnosed acute myeloid leukemia and the relationship with glasdegib treatment and exposure.
    Cancer chemotherapy and pharmacology, 2020, Volume: 86, Issue:4

    Topics: Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Benzimidazoles; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Hedgehog Proteins; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Phenylurea Compounds; Time Factors; Treatment Outcome; United States

2020
CPX-351 treatment in secondary acute myeloblastic leukemia is effective and improves the feasibility of allogeneic stem cell transplantation: results of the Italian compassionate use program.
    Blood cancer journal, 2020, 10-06, Volume: 10, Issue:10

    Topics: Aged; Allografts; Compassionate Use Trials; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Humans; Italy; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasms, Second Primary; Survival Rate

2020
Precision medicine treatment in acute myeloid leukemia using prospective genomic profiling: feasibility and preliminary efficacy of the Beat AML Master Trial.
    Nature medicine, 2020, Volume: 26, Issue:12

    Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cytarabine; Daunorubicin; Female; Genomics; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Precision Medicine; Survival Analysis; Treatment Outcome

2020
Glasdegib plus low-dose cytarabine for acute myeloid leukemia: Practical considerations from advanced practitioners and pharmacists.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2021, Volume: 27, Issue:3

    Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Cytarabine; Drug Interactions; Female; Gastrointestinal Diseases; Hematologic Diseases; Humans; Leukemia, Myeloid, Acute; Male; Pharmacists; Phenylurea Compounds; Physicians

2021
BL-8040 CXCR4 antagonist is safe and demonstrates antileukemic activity in combination with cytarabine for the treatment of relapsed/refractory acute myelogenous leukemia: An open-label safety and efficacy phase 2a study.
    Cancer, 2021, 04-15, Volume: 127, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells; Cytarabine; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Hematopoietic Stem Cell Mobilization; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Peptides; Receptors, CXCR4; Recurrence; Remission Induction

2021
[Comparison of the Curative Efficacy of Elderly Patients with High-Risk MDS and MDS-Transformed AML between Decitabine Combined with Low-Dose CEG Regimen and Decitabine Combined with Low-Dose CAG Regimen].
    Zhongguo shi yan xue ye xue za zhi, 2020, Volume: 28, Issue:6

    Topics: Aclarubicin; Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Decitabine; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Prospective Studies; Treatment Outcome

2020
Murine double minute 2 inhibition alone or with cytarabine in acute myeloid leukemia: Results from an idasanutlin phase 1/1b study⋆.
    Leukemia research, 2021, Volume: 100

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Maximum Tolerated Dose; Middle Aged; para-Aminobenzoates; Prognosis; Proto-Oncogene Proteins c-mdm2; Pyrrolidines; Remission Induction; Tissue Distribution; Young Adult

2021
Defining the Optimal Total Number of Chemotherapy Courses in Younger Patients With Acute Myeloid Leukemia: A Comparison of Three Versus Four Courses.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2021, 03-10, Volume: 39, Issue:8

    Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Follow-Up Studies; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Nucleophosmin; Prognosis; Survival Rate; Young Adult

2021
Augmented Reduced-Intensity Regimen Does Not Improve Postallogeneic Transplant Outcomes in Acute Myeloid Leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2021, 03-01, Volume: 39, Issue:7

    Topics: Adult; Aged; Amsacrine; Busulfan; Cytarabine; Female; Graft vs Host Disease; Humans; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Male; Middle Aged; Myeloablative Agonists; Myelodysplastic Syndromes; Progression-Free Survival; Recurrence; Stem Cell Transplantation; Time Factors; Transplantation Conditioning; Transplantation, Homologous; United Kingdom; Vidarabine; Young Adult

2021
Measurable residual disease in elderly acute myeloid leukemia: results from the PETHEMA-FLUGAZA phase 3 clinical trial.
    Blood advances, 2021, 02-09, Volume: 5, Issue:3

    Topics: Aged; Cytarabine; Humans; Leukemia, Myeloid, Acute; Neoplasm, Residual; Prognosis; Remission Induction

2021
Phase I study of F16IL2 antibody-cytokine fusion with very low-dose araC in acute myeloid leukaemia relapse after allogeneic stem cell transplantation.
    British journal of haematology, 2021, Volume: 192, Issue:6

    Topics: Adult; Allografts; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Hematopoietic Stem Cell Transplantation; Humans; Interleukin-2; Leukemia, Myeloid, Acute; Male; Middle Aged; Recombinant Fusion Proteins

2021
A phase 3 trial of azacitidine versus a semi-intensive fludarabine and cytarabine schedule in older patients with untreated acute myeloid leukemia.
    Cancer, 2021, 06-15, Volume: 127, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Humans; Leukemia, Myeloid, Acute; Remission Induction; Treatment Outcome; Vidarabine

2021
Hybrid chemotherapy regimen (FLAG-IDA-vincristine-prednisone) for acute leukemia with mixed-phenotype blasts.
    Leukemia research, 2021, Volume: 103

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisone; Retrospective Studies; Survival Rate; Vidarabine; Vincristine

2021
Autologous hematopoietic cell transplantation following high-dose cytarabine consolidation for core-binding factor-acute myeloid leukemia in first complete remission: a phase 2 prospective trial.
    International journal of hematology, 2021, Volume: 113, Issue:6

    Topics: Adult; Autografts; Chromosome Aberrations; Chromosomes, Human; Consolidation Chemotherapy; Core Binding Factors; Cytarabine; Disease-Free Survival; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Proteins; Remission Induction; Survival Rate

2021
Older adults with newly diagnosed high-risk/secondary AML who achieved remission with CPX-351: phase 3 post hoc analyses.
    Blood advances, 2021, 03-23, Volume: 5, Issue:6

    Topics: Aged; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Middle Aged; Myelodysplastic Syndromes

2021
Clinical benefit of glasdegib plus low-dose cytarabine in patients with de novo and secondary acute myeloid leukemia: long-term analysis of a phase II randomized trial.
    Annals of hematology, 2021, Volume: 100, Issue:5

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasms, Second Primary; Phenylurea Compounds; Survival Analysis; Treatment Outcome

2021
Phase I study of ADI-PEG20 plus low-dose cytarabine for the treatment of acute myeloid leukemia.
    Cancer medicine, 2021, Volume: 10, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Anemia; Antineoplastic Combined Chemotherapy Protocols; Arginine; Argininosuccinate Synthase; Cytarabine; Drug Administration Schedule; Female; Humans; Hydrolases; Injections, Intramuscular; Injections, Subcutaneous; Leukemia, Myeloid, Acute; Male; Maximum Tolerated Dose; Middle Aged; Neutropenia; Polyethylene Glycols; Thrombocytopenia; Treatment Outcome

2021
A phase I/II study of the combination of quizartinib with azacitidine or low-dose cytarabine for the treatment of patients with acute myeloid leukemia and myelodysplastic syndrome.
    Haematologica, 2021, 08-01, Volume: 106, Issue:8

    Topics: Azacitidine; Benzothiazoles; Cytarabine; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Middle Aged; Mutation; Myelodysplastic Syndromes; Phenylurea Compounds

2021
Comparing cure rates for gemtuzumab ozogamicin plus standard chemotherapy vs standard chemotherapy alone in acute myeloid leukemia patients.
    Future oncology (London, England), 2021, Volume: 17, Issue:22

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Progression-Free Survival; Survival Rate

2021
A phase I trial of selinexor plus FLAG-Ida for the treatment of refractory/relapsed adult acute myeloid leukemia patients.
    Annals of hematology, 2021, Volume: 100, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Hydrazines; Idarubicin; Leukemia, Myeloid, Acute; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Recurrence, Local; Treatment Outcome; Triazoles; Vidarabine

2021
A randomised evaluation of low-dose cytosine arabinoside (ara-C) plus tosedostat versus low-dose ara-C in older patients with acute myeloid leukaemia: results of the LI-1 trial.
    British journal of haematology, 2021, Volume: 194, Issue:2

    Topics: Age Factors; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Enzyme Inhibitors; Female; Glycine; Humans; Hydroxamic Acids; Leukemia, Myeloid, Acute; Male; Middle Aged; Survival Analysis

2021
Venetoclax Combined With FLAG-IDA Induction and Consolidation in Newly Diagnosed and Relapsed or Refractory Acute Myeloid Leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2021, 09-01, Volume: 39, Issue:25

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Remission Induction; Sulfonamides; Survival Rate; Vidarabine; Young Adult

2021
Gemtuzumab Ozogamicin Improves Event-Free Survival and Reduces Relapse in Pediatric
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2021, 10-01, Volume: 39, Issue:28

    Topics: Adolescent; Anthracyclines; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Child; Child, Preschool; Cytarabine; Female; Gemtuzumab; Gene Rearrangement; Hematopoietic Stem Cell Transplantation; Histone-Lysine N-Methyltransferase; Humans; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Male; Myeloid-Lymphoid Leukemia Protein; Progression-Free Survival; Recurrence; Risk Assessment; Risk Factors; Time Factors; United States

2021
Phase 3 randomized trial of chemotherapy with or without oblimersen in older AML patients: CALGB 10201 (Alliance).
    Blood advances, 2021, 07-13, Volume: 5, Issue:13

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Leukemia, Myeloid, Acute; Thionucleotides

2021
Quality-adjusted Time Without Symptoms of disease or Toxicity (Q-TWiST) analysis of CPX-351 versus 7 + 3 in older adults with newly diagnosed high-risk/secondary AML.
    Journal of hematology & oncology, 2021, 07-13, Volume: 14, Issue:1

    Topics: Age Factors; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasms, Second Primary; Quality of Life; Survival Analysis

2021
Venetoclax plus low-dose cytarabine in Japanese patients with untreated acute myeloid leukaemia ineligible for intensive chemotherapy.
    Japanese journal of clinical oncology, 2021, Aug-30, Volume: 51, Issue:9

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Humans; Japan; Leukemia, Myeloid, Acute; Sulfonamides

2021
Efficacy and Safety of Azacytidine in Combination With Fludarabine and High-Dose Cytarabine With G-CSF (FLAG) in Relapsed/Refractory Acute Myeloid Leukemia: A Nonrandomized, Open-Label, Phase II Study.
    Clinical lymphoma, myeloma & leukemia, 2021, Volume: 21, Issue:10

    Topics: Adolescent; Adult; Azacitidine; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Vidarabine; Young Adult

2021
Improved outcomes for myeloid leukemia of Down syndrome: a report from the Children's Oncology Group AAML0431 trial.
    Blood, 2017, 06-22, Volume: 129, Issue:25

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Cytarabine; Cytogenetic Analysis; Daunorubicin; Disease-Free Survival; Down Syndrome; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Myelodysplastic Syndromes; Neoplasm, Residual; Treatment Outcome

2017
A phase 1 study of the CXCR4 antagonist plerixafor in combination with high-dose cytarabine and etoposide in children with relapsed or refractory acute leukemias or myelodysplastic syndrome: A Pediatric Oncology Experimental Therapeutics Investigators' Co
    Pediatric blood & cancer, 2017, Volume: 64, Issue:8

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Benzylamines; Child; Child, Preschool; Cyclams; Cytarabine; Etoposide; Female; Heterocyclic Compounds; Humans; Leukemia, Myeloid, Acute; Male; Myelodysplastic Syndromes; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, CXCR4; Treatment Outcome; Young Adult

2017
Condensed versus standard schedule of high-dose cytarabine consolidation therapy with pegfilgrastim growth factor support in acute myeloid leukemia.
    Blood cancer journal, 2017, 05-26, Volume: 7, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Filgrastim; Humans; Length of Stay; Leukemia, Myeloid, Acute; Male; Middle Aged; Platelet Transfusion; Polyethylene Glycols; Survival Rate

2017
Mitoxantrone, etoposide and cytarabine following epigenetic priming with decitabine in adults with relapsed/refractory acute myeloid leukemia or other high-grade myeloid neoplasms: a phase 1/2 study.
    Leukemia, 2017, Volume: 31, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Biomarkers; Cytarabine; Decitabine; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Neoplasm Grading; Recurrence; Treatment Outcome; Young Adult

2017
Decreased relapsed rate and treatment-related mortality contribute to improved outcomes for pediatric acute myeloid leukemia in successive clinical trials.
    Cancer, 2017, Oct-01, Volume: 123, Issue:19

    Topics: Adolescent; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cladribine; Clinical Protocols; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Gemtuzumab; Hematopoietic Stem Cell Transplantation; Humans; Induction Chemotherapy; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Neoplasm, Residual; Recurrence; Retrospective Studies; Survival Analysis; Time Factors; Treatment Outcome; Young Adult

2017
Phase Ib study of the mTOR inhibitor everolimus with low dose cytarabine in elderly acute myeloid leukemia.
    Leukemia & lymphoma, 2018, Volume: 59, Issue:2

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Everolimus; Humans; Leukemia, Myeloid, Acute; Survival Analysis; TOR Serine-Threonine Kinases; Treatment Outcome

2018
Population Pharmacokinetics of Volasertib Administered in Patients with Acute Myeloid Leukaemia as a Single Agent or in Combination with Cytarabine.
    Clinical pharmacokinetics, 2018, Volume: 57, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Body Surface Area; Cytarabine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Pteridines; Tissue Distribution

2018
Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation.
    The New England journal of medicine, 2017, 08-03, Volume: 377, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; fms-Like Tyrosine Kinase 3; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Protein Kinase Inhibitors; Staurosporine; Young Adult

2017
Intensive consolidation with G-CSF support: Tolerability, safety, reduced hospitalization, and efficacy in acute myeloid leukemia patients ≥60 years.
    American journal of hematology, 2017, Volume: 92, Issue:10

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Consolidation Chemotherapy; Cytarabine; Disease-Free Survival; Drug Administration Schedule; Feasibility Studies; Filgrastim; Granulocyte Colony-Stimulating Factor; Hospitalization; Humans; Leukemia, Myeloid, Acute; Middle Aged; Neutropenia; Polyethylene Glycols; Prognosis; Recombinant Proteins; Vidarabine

2017
A randomized phase 2 study of idarubicin and cytarabine with clofarabine or fludarabine in patients with newly diagnosed acute myeloid leukemia.
    Cancer, 2017, Nov-15, Volume: 123, Issue:22

    Topics: Adenine Nucleotides; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cytarabine; Humans; Idarubicin; Leukemia, Myeloid, Acute; Middle Aged; Neoadjuvant Therapy; Treatment Outcome; Vidarabine; Young Adult

2017
A phase I/II randomized trial of clofarabine or fludarabine added to idarubicin and cytarabine for adults with relapsed or refractory acute myeloid leukemia.
    Leukemia & lymphoma, 2018, Volume: 59, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Clofarabine; Cytarabine; Drug Resistance, Neoplasm; Humans; Idarubicin; Leukemia, Myeloid, Acute; Middle Aged; Neoplasm Recurrence, Local; Progression-Free Survival; Remission Induction; Survival Rate; Treatment Outcome; Vidarabine; Young Adult

2018
Ultrasensitive mutation detection identifies rare residual cells causing acute myelogenous leukemia relapse.
    The Journal of clinical investigation, 2017, Sep-01, Volume: 127, Issue:9

    Topics: Adult; Aged; Alleles; Anthracyclines; Bone Marrow; Cytarabine; Exome; Female; Hematopoiesis; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Neoplasm Recurrence, Local; Neoplasm, Residual; Phenotype; Prognosis; Remission Induction; Stem Cell Transplantation; Time Factors; Transplantation, Homologous; Treatment Outcome; Young Adult

2017
Randomized phase II trial of cytosine arabinoside with and without the CHK1 inhibitor MK-8776 in relapsed and refractory acute myeloid leukemia.
    Leukemia research, 2017, Volume: 61

    Topics: Adult; Aged; Antineoplastic Agents; Checkpoint Kinase 1; Cytarabine; Drug Resistance, Neoplasm; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Recurrence, Local; Pyrazoles; Pyrimidines

2017
Low-dose lenalidomide plus cytarabine in very elderly, unfit acute myeloid leukemia patients: Final result of a phase II study.
    Leukemia research, 2017, Volume: 62

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cytarabine; Disease-Free Survival; Female; Gene Expression Profiling; Humans; Lenalidomide; Leukemia, Myeloid, Acute; Male; Thalidomide; Transcriptome; Treatment Outcome

2017
A multicenter, randomized study of decitabine as epigenetic priming with induction chemotherapy in children with AML.
    Clinical epigenetics, 2017, Volume: 9

    Topics: Adolescent; Azacitidine; Child; Child, Preschool; Cytarabine; Daunorubicin; Decitabine; DNA Methylation; Epigenesis, Genetic; Etoposide; Female; Humans; Induction Chemotherapy; Infant; Leukemia, Myeloid, Acute; Male; Promoter Regions, Genetic; Treatment Outcome

2017
A phase I study of lenalidomide plus chemotherapy with mitoxantrone, etoposide, and cytarabine for the reinduction of patients with acute myeloid leukemia.
    American journal of hematology, 2018, Volume: 93, Issue:2

    Topics: Adult; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Humans; Lenalidomide; Leukemia, Myeloid, Acute; Maximum Tolerated Dose; Mitoxantrone; Remission Induction; Salvage Therapy; Survival Analysis

2018
Persistent cytarabine and daunorubicin exposure after administration of novel liposomal formulation CPX-351: population pharmacokinetic assessment.
    Cancer chemotherapy and pharmacology, 2018, Volume: 81, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Liposomes; Male

2018
Acute Myeloid Leukemia With Central Nervous System Involvement in Children: Experience From the French Protocol Analysis ELAM02.
    Journal of pediatric hematology/oncology, 2018, Volume: 40, Issue:1

    Topics: Adolescent; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Case-Control Studies; Central Nervous System Neoplasms; Child; Child, Preschool; Cytarabine; France; Humans; Infant; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukocyte Count; Prognosis; Recurrence; Survival Analysis

2018
Azacitidine improves clinical outcomes in older patients with acute myeloid leukaemia with myelodysplasia-related changes compared with conventional care regimens.
    BMC cancer, 2017, Dec-14, Volume: 17, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Cytarabine; Female; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Myelodysplastic Syndromes; Prognosis; Treatment Outcome

2017
Unsatisfactory efficacy in randomized study of reduced-dose CPX-351 for medically less fit adults with newly diagnosed acute myeloid leukemia or other high-grade myeloid neoplasm.
    Haematologica, 2018, Volume: 103, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Physical Fitness; Survival Analysis; Treatment Outcome

2018
Prospective randomization of post-remission therapy comparing autologous peripheral blood stem cell transplantation versus high-dose cytarabine consolidation for acute myelogenous leukemia in first remission.
    International journal of hematology, 2018, Volume: 107, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Autografts; Consolidation Chemotherapy; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Peripheral Blood Stem Cell Transplantation; Prospective Studies; Remission Induction; Treatment Outcome; Young Adult

2018
Intermediate-dose cytarabine plus mitoxantrone versus standard-dose cytarabine plus daunorubicin for acute myeloid leukemia in elderly patients.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2018, 04-01, Volume: 29, Issue:4

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Remission Induction; Survival Analysis

2018
A phase I-II study of plerixafor in combination with fludarabine, idarubicin, cytarabine, and G-CSF (PLERIFLAG regimen) for the treatment of patients with the first early-relapsed or refractory acute myeloid leukemia.
    Annals of hematology, 2018, Volume: 97, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Benzylamines; Cyclams; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Heterocyclic Compounds; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Remission Induction; Survival Rate; Vidarabine; Young Adult

2018
Flai (fludarabine, cytarabine, idarubicin) plus low-dose Gemtuzumab Ozogamicin as induction therapy in CD33-positive AML: Final results and long term outcome of a phase II multicenter clinical trial.
    American journal of hematology, 2018, Volume: 93, Issue:5

    Topics: Adolescent; Adult; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Gemtuzumab; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Middle Aged; Sialic Acid Binding Ig-like Lectin 3; Treatment Outcome; Vidarabine; Young Adult

2018
Report of the relapsed/refractory cohort of SWOG S0919: A phase 2 study of idarubicin and cytarabine in combination with pravastatin for acute myelogenous leukemia (AML).
    Leukemia research, 2018, Volume: 67

    Topics: Adult; Aged; Anticholesteremic Agents; Antineoplastic Combined Chemotherapy Protocols; Cholesterol; Cohort Studies; Combined Modality Therapy; Cytarabine; Cytogenetic Analysis; Female; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Pravastatin; Recurrence; Remission Induction; Risk Factors; Survival Analysis; Treatment Outcome; Young Adult

2018
Sirolimus enhances remission induction in patients with high risk acute myeloid leukemia and mTORC1 target inhibition.
    Investigational new drugs, 2018, Volume: 36, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Mechanistic Target of Rapamycin Complex 1; Middle Aged; Mitoxantrone; Phosphorylation; Pilot Projects; Remission Induction; Signal Transduction; Sirolimus

2018
Phase 3 results for vosaroxin/cytarabine in the subset of patients ≥60 years old with refractory/early relapsed acute myeloid leukemia.
    Haematologica, 2018, Volume: 103, Issue:11

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Naphthyridines; Recurrence; Thiazoles

2018
Phase I dose-escalation trial investigating volasertib as monotherapy or in combination with cytarabine in patients with relapsed/refractory acute myeloid leukaemia.
    British journal of haematology, 2019, Volume: 184, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Maximum Tolerated Dose; Middle Aged; Pteridines; Salvage Therapy

2019
Evaluation of high-dose cytarabine in induction therapy for children with de novo acute myeloid leukemia: a study protocol of the Japan Children's Cancer Group Multi-Center Seamless Phase II-III Randomized Trial (JPLSG AML-12).
    Japanese journal of clinical oncology, 2018, Jun-01, Volume: 48, Issue:6

    Topics: Child; Cytarabine; Dose-Response Relationship, Drug; Follow-Up Studies; Humans; Japan; Leukemia, Myeloid, Acute

2018
Molecular remission at the end of treatment is a necessary goal for a good outcome in ELN favorable-risk acute myeloid leukemia: a real-life analysis on 201 patients by the Rete Ematologica Lombarda network.
    Annals of hematology, 2018, Volume: 97, Issue:11

    Topics: Adult; Aged; Cytarabine; Disease-Free Survival; Female; Humans; Italy; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Neoplasm Proteins; Nucleophosmin; Remission Induction; Survival Rate

2018
Influence of UGT1A1 polymorphisms on the outcome of acute myeloid leukemia patients treated with cytarabine-base regimens.
    Journal of translational medicine, 2018, 07-17, Volume: 16, Issue:1

    Topics: Adult; Cytarabine; Female; Follow-Up Studies; Genetic Association Studies; Glucuronosyltransferase; Humans; Leukemia, Myeloid, Acute; Male; Multivariate Analysis; Polymorphism, Single Nucleotide; Prognosis; Proportional Hazards Models; Remission Induction; Risk Factors; Treatment Outcome

2018
CPX-351 (cytarabine and daunorubicin) Liposome for Injection Versus Conventional Cytarabine Plus Daunorubicin in Older Patients With Newly Diagnosed Secondary Acute Myeloid Leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2018, 09-10, Volume: 36, Issue:26

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasms, Second Primary

2018
A phase 1 trial evaluating thioridazine in combination with cytarabine in patients with acute myeloid leukemia.
    Blood advances, 2018, 08-14, Volume: 2, Issue:15

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dopamine D2 Receptor Antagonists; Female; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Male; Middle Aged; Thioridazine

2018
Final results of a randomized multicenter phase II study of alvocidib, cytarabine, and mitoxantrone versus cytarabine and daunorubicin (7 + 3) in newly diagnosed high-risk acute myeloid leukemia (AML).
    Leukemia research, 2018, Volume: 72

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Flavonoids; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Piperidines; Risk Factors

2018
Sequential high-dose cytarabine and mitoxantrone (S-HAM) versus standard double induction in acute myeloid leukemia-a phase 3 study.
    Leukemia, 2018, Volume: 32, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Remission Induction; Young Adult

2018
Outcomes of fludarabine, high dose cytarabine and granulocyte-colony stimulating factor (FLAG) as re-induction for residual acute myeloid leukemia on day 14 bone marrow.
    Leukemia research, 2018, Volume: 74

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm, Residual; Retrospective Studies; Risk Factors; Time Factors; Vidarabine

2018
Preconditioning with fludarabine, busulfan and cytarabine versus standard BuCy2 for patients with acute myeloid leukemia: a prospective, randomized phase II study.
    Bone marrow transplantation, 2019, Volume: 54, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cyclophosphamide; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prospective Studies; Vidarabine; Young Adult

2019
A randomized trial of three novel regimens for recurrent acute myeloid leukemia demonstrates the continuing challenge of treating this difficult disease.
    American journal of hematology, 2019, Volume: 94, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cytarabine; Disease-Free Survival; Etoposide; Female; Flavonoids; Follow-Up Studies; Gastrointestinal Diseases; Hematologic Diseases; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Piperidines; Recurrence; Remission Induction; Salvage Therapy; Sirolimus; Topotecan; Tumor Lysis Syndrome

2019
Phase I/II study on cytarabine and idarubicin combined with escalating doses of clofarabine in newly diagnosed patients with acute myeloid leukaemia and high risk for induction failure (AMLSG 17-10 CIARA trial).
    British journal of haematology, 2018, Volume: 183, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clofarabine; Cytarabine; Dose-Response Relationship, Drug; Female; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Maximum Tolerated Dose; Middle Aged; Remission Induction

2018
Cost Effectiveness of Midostaurin in the Treatment of Newly Diagnosed FLT3-Mutated Acute Myeloid Leukemia in the United States.
    PharmacoEconomics, 2019, Volume: 37, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cost-Benefit Analysis; Cytarabine; Daunorubicin; Double-Blind Method; Female; fms-Like Tyrosine Kinase 3; Health Care Costs; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Models, Theoretical; Quality-Adjusted Life Years; Staurosporine; Survival Rate; Treatment Outcome; United States

2019
A phase I trial investigating the Aurora B kinase inhibitor BI 811283 in combination with cytarabine in patients with acute myeloid leukaemia.
    British journal of haematology, 2019, Volume: 185, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Aurora Kinase B; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Proteins; Protein Kinase Inhibitors

2019
FDA Approval Summary: (Daunorubicin and Cytarabine) Liposome for Injection for the Treatment of Adults with High-Risk Acute Myeloid Leukemia.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2019, 05-01, Volume: 25, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Approval; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Liposomes; Male; Middle Aged; Prognosis; Risk Factors; Survival Rate; United States; United States Food and Drug Administration

2019
Randomized comparison of low dose cytarabine with or without glasdegib in patients with newly diagnosed acute myeloid leukemia or high-risk myelodysplastic syndrome.
    Leukemia, 2019, Volume: 33, Issue:2

    Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Benzimidazoles; Cytarabine; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Phenylurea Compounds; Prognosis; Survival Rate

2019
c-D-index is a risk factor for prolonged febrile neutropenia during chemotherapy in patients with acute myeloid leukemia.
    International journal of clinical oncology, 2019, Volume: 24, Issue:5

    Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Febrile Neutropenia; Female; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Neutrophils; Respiratory Tract Infections; Retrospective Studies; Risk Factors

2019
Homoharringtonine is a safe and effective substitute for anthracyclines in children younger than 2 years old with acute myeloid leukemia.
    Frontiers of medicine, 2019, Volume: 13, Issue:3

    Topics: Anthracyclines; China; Cytarabine; Disease-Free Survival; Female; Hematopoietic Stem Cell Transplantation; Homoharringtonine; Humans; Infant; Leukemia, Myeloid, Acute; Male; Neoadjuvant Therapy; Remission Induction

2019
Phase II study of FLAGM (fludarabine + high-dose cytarabine + granulocyte colony-stimulating factor + mitoxantrone) for relapsed or refractory acute myeloid leukemia.
    International journal of hematology, 2019, Volume: 109, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Recurrence; Survival Rate; Vidarabine

2019
Phase 1-2 safety, efficacy and pharmacokinetic study of decitabine in sequential administration with cytarabine in children with relapsed or refractory acute myeloid leukaemia.
    British journal of haematology, 2019, Volume: 186, Issue:3

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Decitabine; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Neoplasm Recurrence, Local; Treatment Outcome

2019
Venetoclax Combined With Low-Dose Cytarabine for Previously Untreated Patients With Acute Myeloid Leukemia: Results From a Phase Ib/II Study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2019, 05-20, Volume: 37, Issue:15

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Sulfonamides

2019
Comparison of efficacy of HCAG and FLAG re-induction chemotherapy in acute myeloid leukemia patients of low- and intermediate-risk groups.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2019, Volume: 21, Issue:11

    Topics: Aclarubicin; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Female; Granulocyte Colony-Stimulating Factor; Homoharringtonine; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Progression-Free Survival; Prospective Studies; Risk; Single-Blind Method; Treatment Failure; Vidarabine

2019
Genetic polymorphisms of histone methyltransferase SETD2 predicts prognosis and chemotherapy response in Chinese acute myeloid leukemia patients.
    Journal of translational medicine, 2019, 03-28, Volume: 17, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; China; Cytarabine; Female; Follow-Up Studies; Genotype; Histone-Lysine N-Methyltransferase; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Polymorphism, Single Nucleotide; Prognosis; Remission Induction; Survival Analysis; Treatment Outcome; Young Adult

2019
Combination of decitabine, idarubicin, cytarabine, and G-CSF (DIAG) regimen for the treatment of high-risk myelodysplastic syndrome and acute myeloid leukemia.
    Annals of hematology, 2019, Volume: 98, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Decitabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes

2019
A Phase I/II Trial of MEC (Mitoxantrone, Etoposide, Cytarabine) in Combination with Ixazomib for Relapsed Refractory Acute Myeloid Leukemia.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2019, 07-15, Volume: 25, Issue:14

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Boron Compounds; Cytarabine; Drug Resistance, Neoplasm; Etoposide; Female; Glycine; Humans; Leukemia, Myeloid, Acute; Maximum Tolerated Dose; Middle Aged; Mitoxantrone; Neoplasm Recurrence, Local; Patient Safety; Remission Induction; Salvage Therapy; Treatment Outcome

2019
FDA Approval Summary: Glasdegib for Newly Diagnosed Acute Myeloid Leukemia.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2019, 10-15, Volume: 25, Issue:20

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents; Benzimidazoles; Comorbidity; Cytarabine; Dose-Response Relationship, Drug; Drug Approval; Drug Labeling; Female; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Phenylurea Compounds; Smoothened Receptor; Survival Analysis; Treatment Outcome; United States; United States Food and Drug Administration

2019
A phase 2 study to assess the pharmacokinetics and pharmacodynamics of CPX-351 and its effects on cardiac repolarization in patients with acute leukemias.
    Cancer chemotherapy and pharmacology, 2019, Volume: 84, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Combinations; Female; Half-Life; Humans; Leukemia, Myeloid, Acute; Liposomes; Male; Middle Aged; Treatment Outcome

2019
Preclinical activity and a pilot phase I study of pacritinib, an oral JAK2/FLT3 inhibitor, and chemotherapy in FLT3-ITD-positive AML.
    Investigational new drugs, 2020, Volume: 38, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Cell Line, Tumor; Cell Survival; Cytarabine; Daunorubicin; Decitabine; Drug Resistance, Neoplasm; Female; fms-Like Tyrosine Kinase 3; Humans; Janus Kinase 2; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Pilot Projects; Protein Kinase Inhibitors; Pyrimidines

2020
Evaluation of event-free survival as a robust end point in untreated acute myeloid leukemia (Alliance A151614).
    Blood advances, 2019, 06-11, Volume: 3, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Allografts; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; Hematopoietic Stem Cell Transplantation; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Survival Rate

2019
Clinical Experience With Ibrutinib Alone or in Combination With Either Cytarabine or Azacitidine in Patients With Acute Myeloid Leukemia.
    Clinical lymphoma, myeloma & leukemia, 2019, Volume: 19, Issue:8

    Topics: Adenine; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cohort Studies; Cytarabine; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Non-Randomized Controlled Trials as Topic; Piperidines; Prognosis; Pyrazoles; Pyrimidines; Remission Induction; Survival Rate

2019
Prognostic significance of baseline FLT3-ITD mutant allele level in acute myeloid leukemia treated with intensive chemotherapy with/without sorafenib.
    American journal of hematology, 2019, Volume: 94, Issue:9

    Topics: Adolescent; Adult; Aged; Alleles; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; fms-Like Tyrosine Kinase 3; Follow-Up Studies; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Retrospective Studies; Sorafenib; Survival Rate; Tandem Repeat Sequences

2019
Gal9/Tim-3 expression level is higher in AML patients who fail chemotherapy.
    Journal for immunotherapy of cancer, 2019, 07-10, Volume: 7, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells; Cytarabine; Drug Resistance, Neoplasm; Female; Galectins; Hepatitis A Virus Cellular Receptor 2; Humans; Hydrazines; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; T-Lymphocyte Subsets; Treatment Failure; Triazoles

2019
Translational phase I trial of vorinostat (suberoylanilide hydroxamic acid) combined with cytarabine and etoposide in patients with relapsed, refractory, or high-risk acute myeloid leukemia.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2013, Apr-01, Volume: 19, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cytarabine; Etoposide; Female; Gene Expression Regulation, Leukemic; Humans; Hydroxamic Acids; Karyotype; Leukemia, Myeloid, Acute; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Proteins; Recurrence; Translational Research, Biomedical; Treatment Outcome; Tumor Necrosis Factor Decoy Receptors; Vorinostat; Young Adult

2013
Etoposide in combination with low-dose CAG (cytarabine, aclarubicin, G-CSF) for the treatment of relapsed or refractory acute myeloid leukemia: a multicenter, randomized control trial in southwest China.
    Leukemia research, 2013, Volume: 37, Issue:6

    Topics: Aclarubicin; Adolescent; Adult; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; China; Cytarabine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Treatment Failure; Treatment Outcome; Young Adult

2013
Comprehensive genetic analysis of cytarabine sensitivity in a cell-based model identifies polymorphisms associated with outcome in AML patients.
    Blood, 2013, May-23, Volume: 121, Issue:21

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Cytarabine; Drug Resistance, Neoplasm; Gene Expression Regulation, Leukemic; Genome-Wide Association Study; Genotype; Humans; Leukemia, Myeloid, Acute; Phenotype; Polymorphism, Single Nucleotide; Treatment Outcome

2013
A phase 3 study of gemtuzumab ozogamicin during induction and postconsolidation therapy in younger patients with acute myeloid leukemia.
    Blood, 2013, Jun-13, Volume: 121, Issue:24

    Topics: Adolescent; Adult; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Gemtuzumab; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Survival Rate

2013
Homoharringtonine in combination with cytarabine and aclarubicin in the treatment of refractory/relapsed acute myeloid leukemia: a single-center experience.
    Annals of hematology, 2013, Volume: 92, Issue:8

    Topics: Aclarubicin; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemical and Drug Induced Liver Injury; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Harringtonines; Heart Diseases; Homoharringtonine; Humans; Kaplan-Meier Estimate; Kidney Diseases; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Male; Middle Aged; Recurrence; Remission Induction; Salvage Therapy; Stem Cell Transplantation; Young Adult

2013
Stage I of a phase 2 study assessing the efficacy, safety, and tolerability of barasertib (AZD1152) versus low-dose cytosine arabinoside in elderly patients with acute myeloid leukemia.
    Cancer, 2013, Jul-15, Volume: 119, Issue:14

    Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents; Aurora Kinase B; Aurora Kinases; Cytarabine; Drug Administration Schedule; Female; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Neutropenia; Organophosphates; Protein Serine-Threonine Kinases; Quinazolines; Stomatitis; Treatment Outcome

2013
Association between baseline body mass index and overall survival among patients over age 60 with acute myeloid leukemia.
    American journal of hematology, 2013, Volume: 88, Issue:8

    Topics: Age Factors; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Body Mass Index; Coronary Artery Disease; Cytarabine; Diabetes Mellitus; Disease-Free Survival; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Retrospective Studies; Risk Factors; Survival Rate

2013
High-dose cytarabine consolidation with or without additional amsacrine and mitoxantrone in acute myeloid leukemia: results of the prospective randomized AML2003 trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Jun-10, Volume: 31, Issue:17

    Topics: Adolescent; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Prospective Studies; Remission Induction; Survival Analysis; Treatment Outcome; Young Adult

2013
A phase I study of CPX-351 in combination with busulfan and fludarabine conditioning and allogeneic stem cell transplantation in adult patients with refractory acute leukemia.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2013, Volume: 19, Issue:7

    Topics: Adult; Aged; Busulfan; Case-Control Studies; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myeloablative Agonists; Prognosis; Recurrence; Survival Analysis; Transplantation Conditioning; Transplantation, Homologous; Vidarabine

2013
Development and validation of a single-cell network profiling assay-based classifier to predict response to induction therapy in paediatric patients with de novo acute myeloid leukaemia: a report from the Children's Oncology Group.
    British journal of haematology, 2013, Volume: 162, Issue:2

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Female; Flow Cytometry; Humans; Infant; Intracellular Signaling Peptides and Proteins; Leukemia, Myeloid, Acute; Male; Neoadjuvant Therapy; Prognosis; Prospective Studies; Remission Induction; Retrospective Studies; Single-Cell Analysis; Thioguanine; Treatment Outcome

2013
Outcome of older patients with acute myeloid leukemia in first relapse.
    American journal of hematology, 2013, Volume: 88, Issue:9

    Topics: Age Factors; Aged; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Gemtuzumab; Humans; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Remission Induction; Salvage Therapy; Survival Analysis; Treatment Outcome

2013
Phase I study assessing the safety and tolerability of barasertib (AZD1152) with low-dose cytosine arabinoside in elderly patients with AML.
    Clinical lymphoma, myeloma & leukemia, 2013, Volume: 13, Issue:5

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Organophosphates; Quinazolines; Treatment Outcome

2013
Outcomes in obese and overweight acute myeloid leukemia patients receiving chemotherapy dosed according to actual body weight.
    American journal of hematology, 2013, Volume: 88, Issue:10

    Topics: Adult; Aged; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Body Mass Index; Cytarabine; Disease-Free Survival; Female; Follow-Up Studies; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Obesity; Retrospective Studies; Survival Rate

2013
Clofarabine doubles the response rate in older patients with acute myeloid leukemia but does not improve survival.
    Blood, 2013, Aug-22, Volume: 122, Issue:8

    Topics: Adenine Nucleotides; Aged; Aged, 80 and over; Antineoplastic Agents; Arabinonucleosides; Clofarabine; Cytarabine; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Proportional Hazards Models; Remission Induction; Treatment Outcome

2013
Clofarabine, idarubicin, and cytarabine (CIA) as frontline therapy for patients ≤60 years with newly diagnosed acute myeloid leukemia.
    American journal of hematology, 2013, Volume: 88, Issue:11

    Topics: Adenine Nucleotides; Adult; Age Factors; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Consolidation Chemotherapy; Cytarabine; Drug Eruptions; Follow-Up Studies; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Middle Aged; Nausea; Pilot Projects; Remission Induction; Survival Analysis; Young Adult

2013
Optimization of chemotherapy for younger patients with acute myeloid leukemia: results of the medical research council AML15 trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Sep-20, Volume: 31, Issue:27

    Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Consolidation Chemotherapy; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Infant; Leukemia, Myeloid, Acute; Male; Middle Aged; Treatment Outcome; Vidarabine; Young Adult

2013
Gemtuzumab ozogamicin can reduce minimal residual disease in patients with childhood acute myeloid leukemia.
    Cancer, 2013, Nov-15, Volume: 119, Issue:22

    Topics: Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Male; Neoplasm, Residual; Survival Analysis; Treatment Outcome

2013
Phase I study of GTI-2040, a ribonucleotide reductase antisense, with high dose cytarabine in patients with relapsed/refractory acute myeloid leukemia.
    Leukemia & lymphoma, 2014, Volume: 55, Issue:6

    Topics: Aged; Antimetabolites, Antineoplastic; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Recurrence, Local; Oligodeoxyribonucleotides

2014
Phase II trial to assess the safety and efficacy of clofarabine in combination with low-dose cytarabine in elderly patients with acute myeloid leukemia.
    Annals of hematology, 2014, Volume: 93, Issue:1

    Topics: Adenine Nucleotides; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Comorbidity; Cytarabine; Drug Eruptions; Female; Humans; Leukemia, Myeloid, Acute; Liver Failure; Male; Mucositis; Prospective Studies; Remission Induction

2014
Chemomodulation of sequential high-dose cytarabine by fludarabine in relapsed or refractory acute myeloid leukemia: a randomized trial of the AMLCG.
    Leukemia, 2014, Volume: 28, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Recurrence; Survival Analysis; Vidarabine; Young Adult

2014
Panobinostat enhances cytarabine and daunorubicin sensitivities in AML cells through suppressing the expression of BRCA1, CHK1, and Rad51.
    PloS one, 2013, Volume: 8, Issue:11

    Topics: Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; BRCA1 Protein; Checkpoint Kinase 1; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Agonism; Female; G2 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Leukemic; Heterografts; Humans; Hydroxamic Acids; Indoles; Leukemia, Myeloid, Acute; M Phase Cell Cycle Checkpoints; Male; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Transplantation; Panobinostat; Protein Kinases; Rad51 Recombinase; U937 Cells

2013
A phase II study of elacytarabine in combination with idarubicin and of human equilibrative nucleoside transporter 1 expression in patients with acute myeloid leukemia and persistent blasts after the first induction course.
    Leukemia & lymphoma, 2014, Volume: 55, Issue:9

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Equilibrative Nucleoside Transporter 1; Female; Gene Expression; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Treatment Outcome; Young Adult

2014
High-dose cytarabine in induction treatment improves the outcome of adult patients younger than age 46 years with acute myeloid leukemia: results of the EORTC-GIMEMA AML-12 trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014, Jan-20, Volume: 32, Issue:3

    Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Drug Administration Schedule; Etoposide; Europe; Female; Humans; Induction Chemotherapy; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Risk Assessment; Risk Factors; Treatment Outcome

2014
Recombinant interleukin-2 in patients aged younger than 60 years with acute myeloid leukemia in first complete remission: results from Cancer and Leukemia Group B 19808.
    Cancer, 2014, Apr-01, Volume: 120, Issue:7

    Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Cyclosporins; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Humans; Interleukin-2; Leukemia, Myeloid, Acute; Male; Middle Aged; Recombinant Proteins; Remission Induction; Survival Rate; Treatment Outcome

2014
Elacytarabine in relapsed/refractory acute myeloid leukaemia: an evaluation of clinical efficacy, pharmacokinetics, cardiac safety and effects on lipid profile.
    Leukemia research, 2014, Volume: 38, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Cholesterol; Cytarabine; Drug Administration Schedule; Electrocardiography; Female; Heart; Humans; Leukemia, Myeloid, Acute; Lipoproteins; Male; Middle Aged; Recurrence; Treatment Outcome

2014
Low-dose lenalidomide plus cytarabine induce complete remission that can be predicted by genetic profiling in elderly acute myeloid leukemia patients.
    Leukemia, 2014, Volume: 28, Issue:4

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Lenalidomide; Leukemia, Myeloid, Acute; Prospective Studies; Remission Induction; Thalidomide

2014
Final report of phase II study of sorafenib, cytarabine and idarubicin for initial therapy in younger patients with acute myeloid leukemia.
    Leukemia, 2014, Volume: 28, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Idarubicin; Leukemia, Myeloid, Acute; Niacinamide; Phenylurea Compounds; Sorafenib; Treatment Outcome

2014
Phase I study of cladribine, cytarabine, granulocyte colony stimulating factor (CLAG regimen) and midostaurin and all-trans retinoic acid in relapsed/refractory AML.
    International journal of hematology, 2014, Volume: 99, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cytarabine; Female; fms-Like Tyrosine Kinase 3; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Nuclear Proteins; Nucleophosmin; Recurrence; Remission Induction; Staurosporine; Treatment Outcome; Tretinoin

2014
A niche-like culture system allowing the maintenance of primary human acute myeloid leukemia-initiating cells: a new tool to decipher their chemoresistance and self-renewal mechanisms.
    Stem cells translational medicine, 2014, Volume: 3, Issue:4

    Topics: Animals; Antimetabolites, Antineoplastic; Cytarabine; Drug Resistance, Neoplasm; Female; Heterografts; Humans; Leukemia, Myeloid, Acute; Male; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Transplantation; Neoplastic Stem Cells; Signal Transduction; Stem Cell Niche; Tumor Cells, Cultured

2014
Multivariate and subgroup analyses of a randomized, multinational, phase 3 trial of decitabine vs treatment choice of supportive care or cytarabine in older patients with newly diagnosed acute myeloid leukemia and poor- or intermediate-risk cytogenetics.
    BMC cancer, 2014, Feb-06, Volume: 14

    Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Cytarabine; Cytogenetic Analysis; Decitabine; Female; Humans; Internationality; Leukemia, Myeloid, Acute; Male; Multivariate Analysis; Risk Factors; Treatment Outcome

2014
Prospective, multicenter, phase II study on reducing the dosage of idarubicin and FLAG for patients younger than 65 years with resistant acute myeloid leukemia: a comparison with a higher dosage trial.
    Acta haematologica, 2014, Volume: 132, Issue:1

    Topics: Adolescent; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged; Prospective Studies; Recurrence; Remission Induction; Risk Factors; Treatment Failure; Treatment Outcome; Vidarabine; Young Adult

2014
A phase I study of fludarabine, cytarabine, and oxaliplatin therapy in patients with relapsed or refractory acute myeloid leukemia.
    Clinical lymphoma, myeloma & leukemia, 2014, Volume: 14, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gastrointestinal Diseases; Humans; Hyperbilirubinemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Remission Induction; Salvage Therapy; Treatment Outcome; Vidarabine; Young Adult

2014
Clofarabine in combination with a standard remission induction regimen (cytosine arabinoside and idarubicin) in patients with previously untreated intermediate and bad-risk acute myelogenous leukemia (AML) or high-risk myelodysplastic syndrome (HR-MDS): p
    Annals of hematology, 2014, Volume: 93, Issue:6

    Topics: Adenine Nucleotides; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Consolidation Chemotherapy; Cytarabine; Fatigue; Female; Gastrointestinal Diseases; Humans; Hydroxyurea; Hyperbilirubinemia; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Remission Induction; Risk; Treatment Outcome

2014
Phase 2 trial of CPX-351, a fixed 5:1 molar ratio of cytarabine/daunorubicin, vs cytarabine/daunorubicin in older adults with untreated AML.
    Blood, 2014, May-22, Volume: 123, Issue:21

    Topics: Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Leukemia, Myeloid, Acute; Liposomes; Male; Middle Aged

2014
Survival improvement of poor-prognosis AML/MDS patients by maintenance treatment with low-dose chemotherapy and differentiating agents.
    Annals of hematology, 2014, Volume: 93, Issue:8

    Topics: Adult; Aged; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Consolidation Chemotherapy; Cytarabine; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Maintenance Chemotherapy; Male; Middle Aged; Mitoxantrone; Myelodysplastic Syndromes; Neoplasm, Residual; Prognosis; Proportional Hazards Models; Remission Induction; Risk; Survival Analysis; Topotecan; Transplantation, Autologous; Treatment Outcome; Vidarabine

2014
AAML0523: a report from the Children's Oncology Group on the efficacy of clofarabine in combination with cytarabine in pediatric patients with recurrent acute myeloid leukemia.
    Cancer, 2014, Aug-15, Volume: 120, Issue:16

    Topics: Adenine Nucleotides; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Child; Child, Preschool; Clofarabine; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myeloid, Acute; Male; Young Adult

2014
Valproic acid in combination with all-trans retinoic acid and intensive therapy for acute myeloid leukemia in older patients.
    Blood, 2014, Jun-26, Volume: 123, Issue:26

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Critical Care; Cytarabine; Disease-Free Survival; Drug Synergism; Enzyme Inhibitors; Female; Follow-Up Studies; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Nuclear Proteins; Nucleophosmin; Survival Rate; Tretinoin; Valproic Acid

2014
International randomized phase III study of elacytarabine versus investigator choice in patients with relapsed/refractory acute myeloid leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014, Jun-20, Volume: 32, Issue:18

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Cytogenetic Analysis; Disease-Free Survival; Female; Humans; Hyperbilirubinemia; Hypercholesterolemia; International Cooperation; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Recurrence; Treatment Failure

2014
A Phase 2 study of bortezomib combined with either idarubicin/cytarabine or cytarabine/etoposide in children with relapsed, refractory or secondary acute myeloid leukemia: a report from the Children's Oncology Group.
    Pediatric blood & cancer, 2014, Volume: 61, Issue:10

    Topics: Adolescent; Animals; Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Bortezomib; Child; Child, Preschool; Cytarabine; Dose-Response Relationship, Drug; Etoposide; Female; Humans; Idarubicin; Infant; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Neoplasm Recurrence, Local; Pyrazines; Rabbits; Salvage Therapy; Treatment Outcome; Young Adult

2014
Randomized, phase 2 trial of low-dose cytarabine with or without volasertib in AML patients not suitable for induction therapy.
    Blood, 2014, Aug-28, Volume: 124, Issue:9

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Contraindications; Cytarabine; Disease-Free Survival; Female; Humans; Induction Chemotherapy; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Protein Kinase Inhibitors; Pteridines; Treatment Outcome

2014
MRD assessed by WT1 and NPM1 transcript levels identifies distinct outcomes in AML patients and is influenced by gemtuzumab ozogamicin.
    Oncotarget, 2014, Aug-15, Volume: 5, Issue:15

    Topics: Aged; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Gemtuzumab; Genes, Wilms Tumor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm, Residual; Nuclear Proteins; Nucleophosmin; Prognosis; RNA, Messenger; Treatment Outcome; WT1 Proteins

2014
SWOG0919: a Phase 2 study of idarubicin and cytarabine in combination with pravastatin for relapsed acute myeloid leukaemia.
    British journal of haematology, 2014, Volume: 167, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Pravastatin; Recurrence; Time Factors; Treatment Outcome; Young Adult

2014
A randomized trial of prophylactic palifermin on gastrointestinal toxicity after intensive induction therapy for acute myeloid leukaemia.
    British journal of haematology, 2014, Volume: 167, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Fibroblast Growth Factor 7; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Stomatitis

2014
Impact of pegylated filgrastim in comparison to filgrastim for patients with acute myeloid leukaemia (AML) on high-dose cytarabine (HIDAC) consolidation chemotherapy.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2015, Volume: 23, Issue:3

    Topics: Adolescent; Adult; Chemotherapy-Induced Febrile Neutropenia; Consolidation Chemotherapy; Cytarabine; Dose-Response Relationship, Drug; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Polyethylene Glycols; Recombinant Proteins; Survival Analysis; Treatment Outcome; Young Adult

2015
Phase II, multicenter, randomized trial of CPX-351 (cytarabine:daunorubicin) liposome injection versus intensive salvage therapy in adults with first relapse AML.
    Cancer, 2015, Jan-15, Volume: 121, Issue:2

    Topics: Adult; Aged; Aminoglycosides; Amsacrine; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Gemtuzumab; Humans; Injections; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Liposomes; Male; Middle Aged; Mitoxantrone; Recurrence; Remission Induction; Risk Assessment; Salvage Therapy; Treatment Outcome; Vidarabine

2015
The NPM1 mutation type has no impact on survival in cytogenetically normal AML.
    PloS one, 2014, Volume: 9, Issue:10

    Topics: Adult; Aged; Antineoplastic Agents; Cytarabine; Daunorubicin; Female; fms-Like Tyrosine Kinase 3; Gene Expression; Humans; Induction Chemotherapy; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Mutation; Nuclear Proteins; Nucleophosmin; Prognosis; Remission Induction; Risk Factors; Survival Analysis; Thioguanine; Treatment Outcome

2014
[Treating patients with acute myeloid leukemias (AML) according to the protocol of the AML-01.10 Russian multicenter randomized trial: the coordinating center's results].
    Terapevticheskii arkhiv, 2014, Volume: 86, Issue:7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Maintenance Chemotherapy; Male; Mitoxantrone; Russia

2014
Minimal residual disease as biomarker for optimal biologic dosing of ARA-C in patients with acute myeloid leukemia.
    American journal of hematology, 2015, Volume: 90, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Pharmacological; Biomarkers, Tumor; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm, Residual; Recurrence; Remission Induction; Survival Analysis

2015
A phase 1b/2 study of vosaroxin in combination with cytarabine in patients with relapsed or refractory acute myeloid leukemia.
    Haematologica, 2015, Volume: 100, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Cytarabine; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Maximum Tolerated Dose; Middle Aged; Naphthyridines; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Remission Induction; Salvage Therapy; Survival Rate; Thiazoles; Young Adult

2015
A phase I trial of ribavirin and low-dose cytarabine for the treatment of relapsed and refractory acute myeloid leukemia with elevated eIF4E.
    Haematologica, 2015, Volume: 100, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cytarabine; Drug Resistance, Neoplasm; Eukaryotic Initiation Factor-4E; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Ribavirin; Salvage Therapy; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Young Adult

2015
Re-induction with L-DNR/FLAG improves response after AML relapse, but not long-term survival.
    Klinische Padiatrie, 2014, Volume: 226, Issue:6-7

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Doxorubicin; Female; Follow-Up Studies; Germany; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Neoplasm Recurrence, Local; Polyethylene Glycols; Remission Induction; Retreatment; Selection Bias; Survival Rate; Vidarabine; Young Adult

2014
G-CSF priming, clofarabine, and high dose cytarabine (GCLAC) for upfront treatment of acute myeloid leukemia, advanced myelodysplastic syndrome or advanced myeloproliferative neoplasm.
    American journal of hematology, 2015, Volume: 90, Issue:4

    Topics: Adenine Nucleotides; Adult; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cytarabine; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Flow Cytometry; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Myeloproliferative Disorders; Young Adult

2015
Association of ABCB1 polymorphisms with prognostic outcomes of anthracycline and cytarabine in Chinese patients with acute myeloid leukemia.
    European journal of clinical pharmacology, 2015, Volume: 71, Issue:3

    Topics: Adolescent; Adult; Aged; Anthracyclines; Antimetabolites, Antineoplastic; Asian People; ATP Binding Cassette Transporter, Subfamily B; Cytarabine; Female; Genotype; Haplotypes; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Polymorphism, Single Nucleotide; Recurrence; Survival Analysis; Treatment Outcome; Young Adult

2015
A randomised comparison of the novel nucleoside analogue sapacitabine with low-dose cytarabine in older patients with acute myeloid leukaemia.
    Leukemia, 2015, Volume: 29, Issue:6

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Cytarabine; Cytosine; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Staging; Prognosis; Remission Induction; Survival Rate

2015
Idarubicin, cytarabine, and pravastatin as induction therapy for untreated acute myeloid leukemia and high-risk myelodysplastic syndrome.
    American journal of hematology, 2015, Volume: 90, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; Follow-Up Studies; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Pravastatin; Risk Factors; Survival Rate

2015
Prognostic significance of the Medical Research Council cytogenetic classification compared with the European LeukaemiaNet risk classification system in acute myeloid leukaemia.
    British journal of haematology, 2015, Volume: 170, Issue:4

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cytarabine; Databases, Factual; Disease-Free Survival; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Risk Assessment; Survival Rate; United Kingdom

2015
Phase III open-label randomized study of cytarabine in combination with amonafide L-malate or daunorubicin as induction therapy for patients with secondary acute myeloid leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Apr-10, Volume: 33, Issue:11

    Topics: Adenine; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Humans; Induction Chemotherapy; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged; Naphthalimides; Organophosphonates; Prospective Studies; Remission Induction; Time Factors; Treatment Outcome; Young Adult

2015
Efficacy and safety of decitabine in combination with G-CSF, low-dose cytarabine and aclarubicin in newly diagnosed elderly patients with acute myeloid leukemia.
    Oncotarget, 2015, Mar-20, Volume: 6, Issue:8

    Topics: Aclarubicin; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Decitabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Prospective Studies; Survival Analysis; Treatment Outcome

2015
Effect of genetic profiling on prediction of therapeutic resistance and survival in adult acute myeloid leukemia.
    Leukemia, 2015, Volume: 29, Issue:10

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cohort Studies; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Gene Expression Profiling; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Survival Rate; Young Adult

2015
Vosaroxin and vosaroxin plus low-dose Ara-C (LDAC) vs low-dose Ara-C alone in older patients with acute myeloid leukemia.
    Blood, 2015, May-07, Volume: 125, Issue:19

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Naphthyridines; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Prospective Studies; Remission Induction; Survival Rate; Thiazoles

2015
Final results of a phase 2 trial of clofarabine and low-dose cytarabine alternating with decitabine in older patients with newly diagnosed acute myeloid leukemia.
    Cancer, 2015, Jul-15, Volume: 121, Issue:14

    Topics: Adenine Nucleotides; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Azacitidine; Clofarabine; Cytarabine; Decitabine; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Nausea; Remission Induction; Treatment Outcome

2015
A randomized comparison of daunorubicin 90 mg/m2 vs 60 mg/m2 in AML induction: results from the UK NCRI AML17 trial in 1206 patients.
    Blood, 2015, Jun-18, Volume: 125, Issue:25

    Topics: Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Female; Humans; Induction Chemotherapy; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Young Adult

2015
Oral Debio1143 (AT406), an antagonist of inhibitor of apoptosis proteins, combined with daunorubicin and cytarabine in patients with poor-risk acute myeloid leukemia--results of a phase I dose-escalation study.
    Clinical lymphoma, myeloma & leukemia, 2015, Volume: 15, Issue:7

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Azocines; Benzhydryl Compounds; Cytarabine; Cytokines; Daunorubicin; Dose-Response Relationship, Drug; Female; Humans; Inhibitor of Apoptosis Proteins; Leukemia, Myeloid, Acute; Male; Middle Aged

2015
A phase I/II study of oral clofarabine plus low-dose cytarabine in previously treated acute myeloid leukaemia and high-risk myelodysplastic syndrome patients at least 60 years of age.
    British journal of haematology, 2015, Volume: 170, Issue:3

    Topics: Adenine Nucleotides; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cytarabine; Disease-Free Survival; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Risk Factors; Survival Rate

2015
Busulfan and fludarabine conditioning regimen given at hematological nadir of cytoreduction fludarabine, cytarabine, and idarubicin chemotherapy in patients with refractory acute myeloid leukemia undergoing allogeneic stem cell transplantation: a single a
    Medicine, 2015, Volume: 94, Issue:15

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cytarabine; Disease-Free Survival; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Remission Induction; Stem Cell Transplantation; Transplantation Conditioning; Vidarabine; Young Adult

2015
Long-term outcomes of granulocyte colony-stimulating factor-combined conditioning in allogeneic hematopoietic stem cell transplantation from HLA-identical family donors for myeloid malignancies.
    Leukemia research, 2015, Volume: 39, Issue:6

    Topics: Adolescent; Adult; Allografts; Antimetabolites, Antineoplastic; Bone Marrow Transplantation; Cytarabine; Disease-Free Survival; Family; Female; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; HLA Antigens; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Living Donors; Male; Middle Aged; Myelodysplastic Syndromes; Peripheral Blood Stem Cell Transplantation; Survival Rate; Transplantation Conditioning; Whole-Body Irradiation

2015
A prospective, multicenter phase II study of continuous infusion of FLAG for patients older than 60 yr with resistant acute myeloid leukemia: a comparison with intensive younger patients' trial.
    European journal of haematology, 2016, Volume: 96, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Female; Humans; Idarubicin; Induction Chemotherapy; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged; Multivariate Analysis; Remission Induction; Survival Analysis; Treatment Outcome; Vidarabine

2016
Mito-FLAG with Ara-C as bolus versus continuous infusion in recurrent or refractory AML--long-term results of a prospective randomized intergroup study of the East German Study Group Hematology/Oncology (OSHO) and the Study Alliance Leukemia (SAL).
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:7

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Routes; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Prospective Studies; Salvage Therapy; Survival Rate; Vidarabine; Young Adult

2015
Comparison of consolidation strategies in acute myeloid leukemia: high-dose cytarabine alone versus intermediate-dose cytarabine combined with anthracyclines.
    Annals of hematology, 2015, Volume: 94, Issue:9

    Topics: Adolescent; Adult; Aged; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Consolidation Chemotherapy; Cytarabine; Disease-Free Survival; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Survival Rate

2015
Randomised Introduction of 2-CDA as Intensification during Consolidation for Children with High-risk AML--results from Study AML-BFM 2004.
    Klinische Padiatrie, 2015, Volume: 227, Issue:3

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cladribine; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Idarubicin; Infusions, Intravenous; Leukemia, Myeloid, Acute; Prognosis; Survival Rate

2015
Randomized multicenter phase II study of flavopiridol (alvocidib), cytarabine, and mitoxantrone (FLAM) versus cytarabine/daunorubicin (7+3) in newly diagnosed acute myeloid leukemia.
    Haematologica, 2015, Volume: 100, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Flavonoids; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Piperidines; Survival Rate

2015
A multicenter, phase II study of maintenance azacitidine in older patients with acute myeloid leukemia in complete remission after induction chemotherapy.
    American journal of hematology, 2015, Volume: 90, Issue:9

    Topics: Aged; Aged, 80 and over; Anthracyclines; Antimetabolites, Antineoplastic; Azacitidine; Cytarabine; Female; Humans; Induction Chemotherapy; Injections, Subcutaneous; Leukemia, Myeloid, Acute; Male; Middle Aged; Neutropenia; Pilot Projects; Remission Induction; Survival Analysis; Thrombocytopenia

2015
Panobinostat as part of induction and maintenance for elderly patients with newly diagnosed acute myeloid leukemia: phase Ib/II panobidara study.
    Haematologica, 2015, Volume: 100, Issue:10

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Follow-Up Studies; Humans; Hydroxamic Acids; Idarubicin; Indoles; Induction Chemotherapy; Leukemia, Myeloid, Acute; Maintenance Chemotherapy; Male; Maximum Tolerated Dose; Neoplasm, Residual; Panobinostat; Prognosis; Recurrence; Treatment Outcome

2015
Family History and Relapse in Pediatric Acute Myeloid Leukemia.
    Pediatric blood & cancer, 2015, Volume: 62, Issue:12

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Recurrence; Survival Rate

2015
Vosaroxin plus cytarabine versus placebo plus cytarabine in patients with first relapsed or refractory acute myeloid leukaemia (VALOR): a randomised, controlled, double-blind, multinational, phase 3 study.
    The Lancet. Oncology, 2015, Volume: 16, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Double-Blind Method; Female; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Naphthyridines; Neoplasm Recurrence, Local; Remission Induction; Thiazoles; Treatment Outcome

2015
Idarubicin and cytarabine in combination with gemtuzumab ozogamicin (IAGO) for untreated patients with high-risk MDS or AML evolved from MDS: a phase II study from the EORTC and GIMEMA Leukemia Groups (protocol 06013).
    Annals of hematology, 2015, Volume: 94, Issue:12

    Topics: Adolescent; Adult; Aged; Allografts; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Autografts; Cytarabine; Disease-Free Survival; Female; Gemtuzumab; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Survival Rate

2015
Azacitidine in combination with intensive induction chemotherapy in older patients with acute myeloid leukemia: The AML-AZA trial of the Study Alliance Leukemia.
    Leukemia, 2016, Volume: 30, Issue:3

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Cytogenetic Analysis; Daunorubicin; Female; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Survival Analysis

2016
Addition of sorafenib versus placebo to standard therapy in patients aged 60 years or younger with newly diagnosed acute myeloid leukaemia (SORAML): a multicentre, phase 2, randomised controlled trial.
    The Lancet. Oncology, 2015, Volume: 16, Issue:16

    Topics: Adult; Age Factors; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cytarabine; Daunorubicin; Disease Progression; Disease-Free Survival; Double-Blind Method; Female; Germany; Hematopoietic Stem Cell Transplantation; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoadjuvant Therapy; Niacinamide; Phenylurea Compounds; Proportional Hazards Models; Protein Kinase Inhibitors; Recurrence; Risk Factors; Sorafenib; Time Factors; Transplantation, Homologous; Treatment Outcome

2015
Phase II study of tosedostat with cytarabine or decitabine in newly diagnosed older patients with acute myeloid leukaemia or high-risk MDS.
    British journal of haematology, 2016, Volume: 172, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Decitabine; Female; Glycine; Humans; Hydroxamic Acids; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Remission Induction; Survival Analysis; Treatment Outcome

2016
Rituximab plus hyper-CVAD alternating with MTX/Ara-C in patients with newly diagnosed mantle cell lymphoma: 15-year follow-up of a phase II study from the MD Anderson Cancer Center.
    British journal of haematology, 2016, Volume: 172, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Lymphoma, Mantle-Cell; Male; Methotrexate; Middle Aged; Myelodysplastic Syndromes; Neoplasms, Second Primary; Rituximab; Vincristine

2016
Infectious Complications in Children With Acute Myeloid Leukemia and Down Syndrome: Analysis of the Prospective Multicenter Trial AML-BFM 2004.
    Pediatric blood & cancer, 2016, Volume: 63, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Down Syndrome; Etoposide; Female; Humans; Idarubicin; Infant; Infections; Leukemia, Myeloid, Acute; Male; Mitoxantrone

2016
Increasing intensity of therapies assigned at diagnosis does not improve survival of adults with acute myeloid leukemia.
    Leukemia, 2016, Volume: 30, Issue:6

    Topics: Adult; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Danazol; Disease-Free Survival; Granulocyte Colony-Stimulating Factor; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Stem Cell Transplantation; Survival Rate; Tamoxifen; Transplantation, Autologous; Treatment Outcome; Young Adult

2016
A phase I study of intermediate dose cytarabine in combination with lenalidomide in relapsed/refractory acute myeloid leukemia.
    Leukemia research, 2016, Volume: 43

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; Humans; Lenalidomide; Leukemia, Myeloid, Acute; Male; Middle Aged; Survival Rate; Thalidomide

2016
Salvage therapy with high-dose cytarabine and mitoxantrone in combination with all-trans retinoic acid and gemtuzumab ozogamicin in acute myeloid leukemia refractory to first induction therapy.
    Haematologica, 2016, Volume: 101, Issue:7

    Topics: Adult; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Comorbidity; Consolidation Chemotherapy; Cytarabine; Female; Gemtuzumab; Hematopoietic Stem Cell Transplantation; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Remission Induction; Salvage Therapy; Treatment Outcome; Tretinoin; Young Adult

2016
[Modified Shengma Biejia Decoction Combined with CAG Program for Elderly Acute Myeloid Leuke- mia Patients with Yin Deficiency Toxin Stasis Syndrome].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2016, Volume: 36, Issue:2

    Topics: Aclarubicin; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drugs, Chinese Herbal; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Medicine, Chinese Traditional; Phytotherapy; Yin Deficiency

2016
Impact of aerobic exercise training during chemotherapy on cancer related cognitive impairments in patients suffering from acute myeloid leukemia or myelodysplastic syndrome - Study protocol of a randomized placebo-controlled trial.
    Contemporary clinical trials, 2016, Volume: 49

    Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Bicycling; Cognitive Dysfunction; Cytarabine; Executive Function; Exercise Therapy; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Neuropsychological Tests; Spatial Memory; Treatment Outcome

2016
Infusion of a non-HLA-matched ex-vivo expanded cord blood progenitor cell product after intensive acute myeloid leukaemia chemotherapy: a phase 1 trial.
    The Lancet. Haematology, 2016, Volume: 3, Issue:7

    Topics: Adenine Nucleotides; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cohort Studies; Cord Blood Stem Cell Transplantation; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Staging; Young Adult

2016
SLC29A1 (ENT1) polymorphisms and outcome of complete remission in acute myeloid leukemia.
    Cancer chemotherapy and pharmacology, 2016, Volume: 78, Issue:3

    Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Cell Line, Tumor; Cytarabine; Equilibrative Nucleoside Transporter 1; Female; Genetic Association Studies; Genetic Variation; Genotype; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Polymorphism, Single Nucleotide; Remission Induction; Treatment Outcome; Young Adult

2016
A phase I trial of the human double minute 2 inhibitor (MK-8242) in patients with refractory/recurrent acute myelogenous leukemia (AML).
    Leukemia research, 2016, Volume: 48

    Topics: Adult; Aged; Aged, 80 and over; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Enzyme Inhibitors; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Proto-Oncogene Proteins c-mdm2; Salvage Therapy; Survival Analysis; Treatment Outcome

2016
[Efficacy and safety analysis of different dose idarubicin plus cytarabine regimen as induction chemotherapy for young patients with de-novo acute myeloid leukemia].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2016, Aug-14, Volume: 37, Issue:8

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Middle Aged; Prognosis; Remission Induction

2016
CHK1 as a therapeutic target to bypass chemoresistance in AML.
    Science signaling, 2016, 09-13, Volume: 9, Issue:445

    Topics: Checkpoint Kinase 1; Cytarabine; DNA Replication; Drug Resistance, Neoplasm; Female; Humans; Leukemia, Myeloid, Acute; Male; Neoplasm Proteins; Pyrazoles; Pyrimidines

2016
Fludarabine and cytarabine versus high-dose cytarabine in consolidation treatment of t(8; 21) acute myeloid leukemia: A prospective, randomized study.
    American journal of hematology, 2017, Volume: 92, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Consolidation Chemotherapy; Cytarabine; Disease-Free Survival; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid, Acute; Middle Aged; Mutation; Prospective Studies; Proto-Oncogene Proteins c-kit; Translocation, Genetic; Vidarabine; Young Adult

2017
A Phase I Dose Escalation Study of the Triple Angiokinase Inhibitor Nintedanib Combined with Low-Dose Cytarabine in Elderly Patients with Acute Myeloid Leukemia.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Enzyme Inhibitors; Female; Humans; Indoles; Leukemia, Myeloid, Acute; Male; Middle Aged; Protein Kinase Inhibitors

2016
Low-dose clofarabine in combination with a standard remission induction in patients aged 18-60 years with previously untreated intermediate and bad-risk acute myeloid leukemia or high-risk myelodysplastic syndrome: combined phase I/II results of the EORTC
    Haematologica, 2017, Volume: 102, Issue:2

    Topics: Adenine Nucleotides; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cytarabine; Drug Administration Schedule; Female; Gene Expression; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Oncogene Proteins, Fusion; Random Allocation; Remission Induction; Risk Factors; Survival Analysis; Transplantation, Homologous; Treatment Outcome

2017
Phase I study of the aurora A kinase inhibitor alisertib with induction chemotherapy in patients with acute myeloid leukemia.
    Haematologica, 2017, Volume: 102, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aurora Kinase A; Azepines; Cytarabine; Female; Humans; Idarubicin; Immunohistochemistry; Leukemia, Myeloid, Acute; Male; Middle Aged; Protein Kinase Inhibitors; Pyrimidines; Remission Induction; Survival Analysis; Treatment Outcome

2017
Addition of cladribine to the standard induction treatment improves outcomes in a subset of elderly acute myeloid leukemia patients. Results of a randomized Polish Adult Leukemia Group (PALG) phase II trial.
    American journal of hematology, 2017, Volume: 92, Issue:4

    Topics: Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cytarabine; Daunorubicin; Female; Humans; Induction Chemotherapy; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Poland; Remission Induction

2017
Randomized Phase II Study of Clofarabine-Based Consolidation for Younger Adults With Acute Myeloid Leukemia in First Remission.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, Apr-10, Volume: 35, Issue:11

    Topics: Adenine Nucleotides; Adult; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Consolidation Chemotherapy; Cytarabine; Disease-Free Survival; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Treatment Outcome

2017
A phase 1/2 study of chemosensitization with plerixafor plus G-CSF in relapsed or refractory acute myeloid leukemia.
    Blood cancer journal, 2017, 03-10, Volume: 7, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Autografts; Benzylamines; Cyclams; Cytarabine; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Heterocyclic Compounds; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Stem Cell Transplantation

2017
Phase I study of GTI-2040, an antisense to ribonucleotide reductase, in combination with high-dose cytarabine in patients with acute myeloid leukemia.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, Jun-15, Volume: 14, Issue:12

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myeloid, Acute; Male; Metabolic Clearance Rate; Middle Aged; Oligodeoxyribonucleotides; Oligonucleotides, Antisense; Ribonucleotide Reductases; Treatment Outcome

2008
Patients with acute myeloid leukemia and RAS mutations benefit most from postremission high-dose cytarabine: a Cancer and Leukemia Group B study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Oct-01, Volume: 26, Issue:28

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Genes, ras; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Prognosis; Proportional Hazards Models; Remission Induction; Statistics, Nonparametric; Survival Rate

2008
A randomized study of clofarabine versus clofarabine plus low-dose cytarabine as front-line therapy for patients aged 60 years and older with acute myeloid leukemia and high-risk myelodysplastic syndrome.
    Blood, 2008, Sep-01, Volume: 112, Issue:5

    Topics: Adenine Nucleotides; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Chromosome Aberrations; Clofarabine; Cytarabine; Disease-Free Survival; Drug Administration Schedule; Female; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Myelodysplastic Syndromes; Survival Rate

2008
Phase I study of cladribine, cytarabine (Ara-C), granulocyte colony stimulating factor (G-CSF) (CLAG Regimen) and simultaneous escalating doses of imatinib mesylate (Gleevec) in relapsed/refractory AML.
    Leukemia research, 2008, Volume: 32, Issue:12

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Blast Crisis; Bone Marrow; Cladribine; Cytarabine; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Granulocyte Colony-Stimulating Factor; Humans; Imatinib Mesylate; Leukemia, Myeloid, Acute; Male; Middle Aged; Piperazines; Pyrimidines; Recurrence; Time Factors

2008
A single dose of pegfilgrastim compared with daily filgrastim for supporting neutrophil recovery in patients treated for low-to-intermediate risk acute myeloid leukemia: results from a randomized, double-blind, phase 2 trial.
    BMC cancer, 2008, Jul-10, Volume: 8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Double-Blind Method; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Neutropenia; Neutrophils; Polyethylene Glycols; Recombinant Proteins; Recovery of Function; Remission Induction

2008
Gemtuzumab-ozogamicin in combination with fludarabine, cytarabine, idarubicin (FLAI-GO) as induction therapy in CD33-positive AML patients younger than 65 years.
    Leukemia research, 2008, Volume: 32, Issue:12

    Topics: Adult; Aged; Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Filgrastim; Gemtuzumab; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Recombinant Proteins; Remission Induction; Sialic Acid Binding Ig-like Lectin 3; Vidarabine; Young Adult

2008
Myeloid sarcoma is associated with superior event-free survival and overall survival compared with acute myeloid leukemia.
    Cancer, 2008, Sep-15, Volume: 113, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Sarcoma, Myeloid; Survival Rate; Treatment Outcome

2008
Sequential continuous infusion of fludarabine and cytarabine associated with liposomal daunorubicin (DaunoXome) (FLAD) in primary refractory or relapsed adult acute myeloid leukemia patients.
    Annals of hematology, 2009, Volume: 88, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Liposomes; Male; Middle Aged; Recurrence; Salvage Therapy; Stem Cell Transplantation; Survival Rate; Time Factors; Vidarabine

2009
Clofarabine combinations as acute myeloid leukemia salvage therapy.
    Cancer, 2008, Oct-15, Volume: 113, Issue:8

    Topics: Adenine Nucleotides; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cytarabine; Humans; Idarubicin; Leukemia, Myeloid, Acute; Maximum Tolerated Dose; Middle Aged; Salvage Therapy

2008
Timed sequential induction chemotherapy and risk-adapted postremission therapy for acute myelogenous leukemia.
    American journal of hematology, 2008, Volume: 83, Issue:11

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cohort Studies; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Drug Administration Schedule; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Remission Induction

2008
Single-dose mitoxantrone in combination with continuous infusion intermediate-dose cytarabine plus etoposide for treatment of refractory or early relapsed acute myeloid leukemia.
    Leukemia research, 2009, Volume: 33, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Neoplasm Recurrence, Local; Salvage Therapy; Treatment Outcome

2009
Arsenic trioxide and low-dose cytarabine in older patients with untreated acute myeloid leukemia, excluding acute promyelocytic leukemia.
    Cancer, 2008, Nov-01, Volume: 113, Issue:9

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Oxides; Prognosis; Remission Induction; Survival Rate

2008
Long-term disease-free survival after gemtuzumab, intermediate-dose cytarabine, and mitoxantrone in patients with CD33(+) primary resistant or relapsed acute myeloid leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Nov-10, Volume: 26, Issue:32

    Topics: Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Cytarabine; Disease-Free Survival; Drug Resistance, Neoplasm; Female; France; Gemtuzumab; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Recurrence; Salvage Therapy; Sialic Acid Binding Ig-like Lectin 3; Time Factors; Treatment Failure; Treatment Outcome

2008
Treatment of core-binding-factor in acute myelogenous leukemia with fludarabine, cytarabine, and granulocyte colony-stimulating factor results in improved event-free survival.
    Cancer, 2008, Dec-01, Volume: 113, Issue:11

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Core Binding Factors; Cytarabine; Disease-Free Survival; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Multivariate Analysis; Vidarabine

2008
Outcome of high-dose cytarabine-based induction therapy followed by hematopoietic stem cell transplantation in acute myeloid leukemia: influence of karyotype.
    Leukemia & lymphoma, 2008, Volume: 49, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cytarabine; Etoposide; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Karyotyping; Leukemia, Myeloid, Acute; Middle Aged; Remission Induction; Survival Rate; Treatment Outcome

2008
A phase I study of tipifarnib combined with conventional induction and consolidation therapy for previously untreated patients with acute myeloid leukemia aged 60 years and over.
    Leukemia, 2009, Volume: 23, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug-Related Side Effects and Adverse Reactions; Gastrointestinal Diseases; Humans; Leukemia, Myeloid, Acute; Maximum Tolerated Dose; Middle Aged; Quinolones; Remission Induction

2009
Cyclosporine diminishes multidrug resistance in K562/ADM cells and improves complete remission in patients with acute myeloid leukemia.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2009, Volume: 63, Issue:8

    Topics: Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Survival; Cyclosporine; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Fluorescent Dyes; Humans; Idarubicin; Inhibitory Concentration 50; K562 Cells; Leukemia, Myeloid, Acute; Male; Rhodamine 123; Time Factors; Treatment Outcome; Verapamil

2009
A phase I trial of continuous infusion of the multidrug resistance inhibitor zosuquidar with daunorubicin and cytarabine in acute myeloid leukemia.
    Leukemia research, 2009, Volume: 33, Issue:8

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytarabine; Daunorubicin; Dibenzocycloheptenes; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Quinolines; Time Factors

2009
Dose-dense induction with sequential high-dose cytarabine and mitoxantone (S-HAM) and pegfilgrastim results in a high efficacy and a short duration of critical neutropenia in de novo acute myeloid leukemia: a pilot study of the AMLCG.
    Blood, 2009, Apr-23, Volume: 113, Issue:17

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Neutropenia; Pilot Projects; Polyethylene Glycols; Recombinant Proteins; Societies, Medical; Survival Rate; Time Factors; Treatment Outcome

2009
Allo-SCT conditioning for myelodysplastic syndrome and acute myeloid leukemia with clofarabine, cytarabine and ATG.
    Bone marrow transplantation, 2009, Volume: 44, Issue:1

    Topics: Adenine Nucleotides; Adult; Aged; Antilymphocyte Serum; Antimetabolites, Antineoplastic; Arabinonucleosides; Clofarabine; Cytarabine; Disease-Free Survival; Female; Humans; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Stem Cell Transplantation; Survival Rate; Time Factors; Transplantation Conditioning; Transplantation, Homologous

2009
Twice daily fludarabine/Ara-C associated to idarubicin, G-CSF and ATRA is an effective salvage regimen in non-promyelocytic acute myeloid leukemia.
    Leukemia research, 2009, Volume: 33, Issue:8

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Prospective Studies; Remission Induction; Salvage Therapy; Survival Rate; Tretinoin; Vidarabine

2009
Continuous infusion of intermediate-dose cytarabine and fludarabine with idarubicin for patients younger than 60 years with resistant acute myeloid leukemia: a prospective, multicenter phase II study.
    American journal of hematology, 2009, Volume: 84, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Vidarabine; Young Adult

2009
[Standard-dose of idarubicin in combination with continuous infusion of cytarabine as induction therapy in patients with acute myeloid leukaemia].
    Zhongguo shi yan xue ye xue za zhi, 2009, Volume: 17, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Treatment Outcome; Young Adult

2009
Expression of ABCC-type nucleotide exporters in blasts of adult acute myeloid leukemia: relation to long-term survival.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Mar-01, Volume: 15, Issue:5

    Topics: Adult; Aged; ATP-Binding Cassette Transporters; Blast Crisis; Cell Membrane; Cytarabine; Drug Resistance, Neoplasm; Female; Humans; Leukemia, Myeloid, Acute; LLC-PK1 Cells; Male; Middle Aged; Multidrug Resistance-Associated Proteins; Prognosis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stem Cells; Survival Rate

2009
The impact of dose escalation and resistance modulation in older patients with acute myeloid leukaemia and high risk myelodysplastic syndrome: the results of the LRF AML14 trial.
    British journal of haematology, 2009, Volume: 145, Issue:3

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cyclosporins; Cytarabine; Cytogenetic Analysis; Daunorubicin; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Humans; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Multivariate Analysis; Myelodysplastic Syndromes; Prognosis; Remission Induction; Survival Rate

2009
[A clinical trial for homoharringtonine and low-dose cytosine arabinoside combined with G-CSF or GM-CSF to treat the relapsed or refractory acute myeloid leukemia (AML), geriatric AML and advanced myelodysplastic syndromes].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2009, Volume: 40, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Harringtonines; Homoharringtonine; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Neoplasm Recurrence, Local; Young Adult

2009
Thioguanine pharmacokinetics in induction therapy of children with acute myeloid leukemia.
    Anti-cancer drugs, 2009, Volume: 20, Issue:1

    Topics: Administration, Oral; Adolescent; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Down Syndrome; Doxorubicin; Drug Administration Schedule; Drug Monitoring; Erythrocytes; Etoposide; Female; Guanine Nucleotides; Humans; Infant; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Registries; Scandinavian and Nordic Countries; Thioguanine; Thionucleotides; Treatment Outcome

2009
[Efficacy of induction chemotherapy for patients with high-risk myelodysplastic syndrome (MDS) or MDS-transformed acute myeloid leukemia with CHG regimen and its comparison with regimen GAG and HA].
    Zhongguo shi yan xue ye xue za zhi, 2009, Volume: 17, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Harringtonines; Homoharringtonine; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Young Adult

2009
[IDA-FLAG regimen in treatment of patients with refractory or relapsed acute leukemia].
    Zhongguo shi yan xue ye xue za zhi, 2009, Volume: 17, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Vidarabine

2009
[Low-dose cytarabine and aclarubicin in combination with granulocyte colony-stimulating factor priming in 50 patients with relapsed acute myeloid leukemia].
    Zhongguo shi yan xue ye xue za zhi, 2009, Volume: 17, Issue:3

    Topics: Aclarubicin; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Treatment Outcome; Young Adult

2009
[Clinical study on fludarabine combined with cytarabine regimen in the treatment of patients with refractory and relapsed acute myeloid leukemia].
    Zhongguo shi yan xue ye xue za zhi, 2009, Volume: 17, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Vidarabine

2009
Effect and prognostic analysis of treatment for acute myeloid leukemia using Chinese drugs combined with chemotherapy.
    Chinese journal of integrative medicine, 2009, Volume: 15, Issue:3

    Topics: Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Child; Chromosome Aberrations; Cytarabine; Daunorubicin; Drugs, Chinese Herbal; Etoposide; Female; Humans; Immunophenotyping; Integrative Medicine; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Prognosis; Treatment Outcome; Young Adult

2009
Infectious complications in patients with acute myeloid leukemia treated according to the protocol with daunorubicin and cytarabine with or without addition of cladribine. A multicenter study by the Polish Adult Leukemia Group (PALG).
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2010, Volume: 14, Issue:2

    Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bacteremia; Candida; Cladribine; Cytarabine; Daunorubicin; Female; Fungemia; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Incidence; Leukemia, Myeloid, Acute; Male; Middle Aged; Poland; Treatment Outcome; Young Adult

2010
Regimen containing perarubicin for the treatment of newly diagnosed young patients with acute myeloid leukemia.
    Ai zheng = Aizheng = Chinese journal of cancer, 2009, Volume: 28, Issue:6

    Topics: Adolescent; Adult; Agranulocytosis; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Doxorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Nausea; Recurrence; Remission Induction; Young Adult

2009
Effect of low-dose cytarabine, homoharringtonine and granulocyte colony-stimulating factor priming regimen on patients with advanced myelodysplastic syndrome or acute myeloid leukemia transformed from myelodysplastic syndrome.
    Leukemia & lymphoma, 2009, Volume: 50, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cell Transformation, Neoplastic; Cytarabine; Disease Progression; Dose-Response Relationship, Drug; Female; Granulocyte Colony-Stimulating Factor; Harringtonines; Homoharringtonine; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Neoadjuvant Therapy; Treatment Outcome; Young Adult

2009
[Clinical research of modified CAG regimen for the treatment of relapsed acute myeloid leukemia].
    Zhongguo shi yan xue ye xue za zhi, 2009, Volume: 17, Issue:4

    Topics: Aclarubicin; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Treatment Outcome

2009
Phase 3 randomized, placebo-controlled, double-blind study of high-dose continuous infusion cytarabine alone or with laromustine (VNP40101M) in patients with acute myeloid leukemia in first relapse.
    Blood, 2009, Nov-05, Volume: 114, Issue:19

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Double-Blind Method; Female; Humans; Hydrazines; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Remission Induction; Sulfonamides; Young Adult

2009
FLAIE (fludarabine, cytarabine, idarubicin, and etoposide), a four drug induction chemotherapy for adult acute myeloid leukemia: A single center experience.
    American journal of hematology, 2009, Volume: 84, Issue:10

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Etoposide; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Pilot Projects; Remission Induction; Vidarabine; Young Adult

2009
Low-dose cytarabine and aclarubicin in combination with granulocyte colony-stimulating factor for elderly patients with previously untreated acute myeloid leukemia.
    Leukemia research, 2010, Volume: 34, Issue:5

    Topics: Aclarubicin; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Granulocyte Colony-Stimulating Factor; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged

2010
Phase I trials of amonafide as monotherapy and in combination with cytarabine in patients with poor-risk acute myeloid leukemia.
    Leukemia research, 2010, Volume: 34, Issue:4

    Topics: Adenine; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Naphthalimides; Organophosphonates; Remission Induction; Risk Factors; Treatment Outcome; Young Adult

2010
Failure of three novel regimens to improve outcome for patients with relapsed or refractory acute myeloid leukaemia: a report from the Eastern Cooperative Oncology Group.
    British journal of haematology, 2010, Volume: 148, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Gemtuzumab; Humans; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Liposomes; Male; Middle Aged; Recurrence; Remission Induction; Survival Analysis; Topotecan

2010
Sequential phase II Southwest Oncology Group studies (S0112 and S0301) of daunorubicin and cytarabine by continuous infusion, without and with ciclosporin, in older patients with previously untreated acute myeloid leukaemia.
    British journal of haematology, 2010, Volume: 148, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Cytarabine; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Epidemiologic Methods; Female; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Proteins; Treatment Outcome

2010
[Effect of FLAG consolidation therapy on mobilization of autologous peripheral blood stem cells in patients with acute myelogenous leukemia].
    Zhongguo shi yan xue ye xue za zhi, 2009, Volume: 17, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Peripheral Blood Stem Cell Transplantation; Transplantation, Autologous; Vidarabine; Young Adult

2009
[Clinical study on regimen cyclophosphamide, Ara-C and topotecan (CAT) in treatment of patients with refractory or relapsed acute myelogenous leukemia].
    Zhongguo shi yan xue ye xue za zhi, 2009, Volume: 17, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Topotecan; Young Adult

2009
Clinical activity of sequential flavopiridol, cytosine arabinoside, and mitoxantrone for adults with newly diagnosed, poor-risk acute myelogenous leukemia.
    Leukemia research, 2010, Volume: 34, Issue:7

    Topics: Adult; Aged; Allopurinol; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Female; Flavonoids; Follow-Up Studies; Heart Diseases; Humans; Hyperkalemia; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Piperidines; Polyamines; Premedication; Remission Induction; Risk; Sepsis; Sevelamer; Transplantation, Homologous; Treatment Outcome; Tumor Lysis Syndrome; Young Adult

2010
Report of a phase 1/2 study of a combination of azacitidine and cytarabine in acute myelogenous leukemia and high-risk myelodysplastic syndromes.
    Leukemia & lymphoma, 2010, Volume: 51, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Drug Resistance, Neoplasm; Epigenesis, Genetic; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Remission Induction; Treatment Outcome

2010
[FLAG regimen as consolidation therapy for patients with acute myeloid leukemia].
    Zhongguo shi yan xue ye xue za zhi, 2009, Volume: 17, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Vidarabine; Young Adult

2009
Attempts to optimize induction and consolidation treatment in acute myeloid leukemia: results of the MRC AML12 trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Feb-01, Volume: 28, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Neoplasm Staging; Prognosis; Remission Induction; Survival Rate; Thioguanine; Treatment Outcome; Tretinoin; Young Adult

2010
Comparative analysis of remission induction therapy for high-risk MDS and AML progressed from MDS in the MDS200 study of Japan Adult Leukemia Study Group.
    International journal of hematology, 2010, Volume: 91, Issue:1

    Topics: Aclarubicin; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Idarubicin; Japan; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Remission Induction; Risk Factors; Survival Analysis; Treatment Outcome; Young Adult

2010
Randomized trial of response-oriented individualized versus fixed-schedule induction chemotherapy with idarubicin and cytarabine in adult acute myeloid leukemia: the JALSG AML95 study.
    International journal of hematology, 2010, Volume: 91, Issue:2

    Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Cytarabine; Drug Administration Schedule; Follow-Up Studies; Humans; Idarubicin; Leukemia, Myeloid, Acute; Middle Aged; Precision Medicine; Prognosis; Remission Induction; Treatment Outcome; Young Adult

2010
Allogeneic stem cell transplantation versus chemotherapy as post-remission therapy for intermediate or poor risk adult acute myeloid leukemia: results of the JALSG AML97 study.
    International journal of hematology, 2010, Volume: 91, Issue:2

    Topics: Adolescent; Adult; Age Distribution; Antimetabolites, Antineoplastic; Child; Child, Preschool; Cytarabine; Drug Resistance, Neoplasm; Female; Hematopoietic Stem Cell Transplantation; Humans; Incidence; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Risk Factors; Survival Analysis; Transplantation, Homologous

2010
Phase I/II study of combination therapy with sorafenib, idarubicin, and cytarabine in younger patients with acute myeloid leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Apr-10, Volume: 28, Issue:11

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Cytarabine; Feasibility Studies; Female; fms-Like Tyrosine Kinase 3; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Neoplasm Staging; Niacinamide; Phenylurea Compounds; Pyridines; Sorafenib; Survival Rate; Treatment Outcome; Young Adult

2010
Changes of serum growth factors (IGF-I & IGFBP-2) and prediction of response to chemotherapy in patients with acute myeloid leukemia.
    The Egyptian journal of immunology, 2008, Volume: 15, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Doxorubicin; Enzyme-Linked Immunosorbent Assay; Female; Humans; Insulin-Like Growth Factor Binding Protein 2; Insulin-Like Growth Factor I; Leukemia, Myeloid, Acute; Male; Middle Aged; Predictive Value of Tests; Prognosis; Remission Induction; Treatment Outcome; Young Adult

2008
[Effectiveness of remission induction with high-dose cytarabine for relapsed or refractory pediatric acute leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2010, Volume: 51, Issue:2

    Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Child, Preschool; Cytarabine; Female; Humans; Infant; Invasive Pulmonary Aspergillosis; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pulse Therapy, Drug; Recurrence; Remission Induction; Treatment Outcome

2010
Risk-adapted treatment of acute promyelocytic leukemia based on all-trans retinoic acid and anthracycline with addition of cytarabine in consolidation therapy for high-risk patients: further improvements in treatment outcome.
    Blood, 2010, Jun-24, Volume: 115, Issue:25

    Topics: Adolescent; Adult; Aged; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Risk Adjustment; Risk Factors; Survival Rate; Tretinoin

2010
A Phase 1 study of imatinib mesylate in combination with cytarabine and daunorubicin for c-kit positive relapsed acute myeloid leukemia.
    Leukemia research, 2010, Volume: 34, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Cytarabine; Daunorubicin; Female; Humans; Imatinib Mesylate; Leukemia, Myeloid, Acute; Male; Maximum Tolerated Dose; Middle Aged; Phosphorylation; Piperazines; Proto-Oncogene Proteins c-kit; Pyrimidines; Recurrence; STAT5 Transcription Factor

2010
Prognostic impact of specific chromosomal aberrations in a large group of pediatric patients with acute myeloid leukemia treated uniformly according to trial AML-BFM 98.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Jun-01, Volume: 28, Issue:16

    Topics: Adolescent; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Chromosome Aberrations; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Combined Modality Therapy; Confidence Intervals; Cytarabine; Cytogenetic Analysis; Disease-Free Survival; Etoposide; Female; Follow-Up Studies; Humans; Idarubicin; In Situ Hybridization, Fluorescence; Leukemia, Myeloid, Acute; Male; Probability; Proportional Hazards Models; Radiotherapy, Adjuvant; Reverse Transcriptase Polymerase Chain Reaction; Risk Assessment; Severity of Illness Index; Statistics, Nonparametric; Stem Cell Transplantation; Survival Analysis; Transplantation, Homologous; Treatment Outcome

2010
A novel prognostic model in elderly patients with acute myeloid leukemia: results of 909 patients entered into the prospective AML96 trial.
    Blood, 2010, Aug-12, Volume: 116, Issue:6

    Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Cytarabine; Daunorubicin; Disease-Free Survival; Female; fms-Like Tyrosine Kinase 3; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Multivariate Analysis; Nuclear Proteins; Nucleophosmin; Prognosis; Proportional Hazards Models; Prospective Studies; Remission Induction; Risk Factors

2010
Minimal residual disease-directed therapy for childhood acute myeloid leukaemia: results of the AML02 multicentre trial.
    The Lancet. Oncology, 2010, Volume: 11, Issue:6

    Topics: Adolescent; Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Cytogenetic Analysis; Daunorubicin; Disease-Free Survival; Etoposide; Female; Flow Cytometry; Gemtuzumab; Humans; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Male; Neoplasm, Residual; Remission Induction; Survival Rate; Young Adult

2010
P-glycoprotein inhibition using valspodar (PSC-833) does not improve outcomes for patients younger than age 60 years with newly diagnosed acute myeloid leukemia: Cancer and Leukemia Group B study 19808.
    Blood, 2010, Sep-02, Volume: 116, Issue:9

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporins; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Survival Rate; Treatment Outcome; Young Adult

2010
The associations of Janus kinase-2 (JAK2) A830G polymorphism and the treatment outcomes in patients with acute myeloid leukemia.
    Leukemia & lymphoma, 2010, Volume: 51, Issue:6

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Asian People; China; Cytarabine; Female; Gene Frequency; Genotype; Humans; Janus Kinase 2; Leukemia, Myeloid, Acute; Male; Middle Aged; Polymorphism, Single Nucleotide; Remission Induction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Treatment Outcome; Young Adult

2010
Intensively timed combination chemotherapy for the induction of adult patients with acute myeloid leukemia: long-term follow-up of a phase 2 study.
    Cancer, 2010, Nov-15, Volume: 116, Issue:22

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Dexamethasone; Etoposide; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Thioguanine

2010
High dose cytarabine plus gemtuzumab ozogamicin for patients with relapsed or refractory acute myeloid leukemia: Cancer and Leukemia Group B study 19902.
    Leukemia research, 2011, Volume: 35, Issue:3

    Topics: Aged; Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Case-Control Studies; Cohort Studies; Cytarabine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Gemtuzumab; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Recurrence, Local; Remission Induction; Survival Rate; Treatment Outcome

2011
Randomized study of induction therapy comparing standard-dose idarubicin with high-dose daunorubicin in adult patients with previously untreated acute myeloid leukemia: the JALSG AML201 Study.
    Blood, 2011, Feb-24, Volume: 117, Issue:8

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Humans; Idarubicin; Leukemia, Myeloid, Acute; Middle Aged; Remission Induction; Survival Analysis; Young Adult

2011
Brain perfusion in adult patients with acute myeloblastic leukemia before and after cytosine arabinoside.
    Molecular imaging and biology, 2011, Volume: 13, Issue:4

    Topics: Adolescent; Adult; Aged; Brain; Cerebrovascular Circulation; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Perfusion; Tomography, Emission-Computed, Single-Photon; Young Adult

2011
Sequential cytarabine and alpha-particle immunotherapy with bismuth-213-lintuzumab (HuM195) for acute myeloid leukemia.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2010, Nov-01, Volume: 16, Issue:21

    Topics: Adult; Aged; Aged, 80 and over; Alpha Particles; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Bismuth; Cytarabine; Drug Administration Schedule; Female; Humans; Immunoconjugates; Leukemia, Myeloid, Acute; Male; Middle Aged; Radioimmunotherapy; Radioisotopes; Remission Induction

2010
XIAP antisense oligonucleotide (AEG35156) achieves target knockdown and induces apoptosis preferentially in CD34+38- cells in a phase 1/2 study of patients with relapsed/refractory AML.
    Apoptosis : an international journal on programmed cell death, 2011, Volume: 16, Issue:1

    Topics: Aged; Antigens, CD; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caspases; Cytarabine; Drug Administration Schedule; Drug Dosage Calculations; Female; Gene Expression; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Myeloid Progenitor Cells; Oligonucleotides; Recurrence; RNA, Messenger; X-Linked Inhibitor of Apoptosis Protein

2011
A phase 1-2 study of a farnesyltransferase inhibitor, tipifarnib, combined with idarubicin and cytarabine for patients with newly diagnosed acute myeloid leukemia and high-risk myelodysplastic syndrome.
    Cancer, 2011, Mar-15, Volume: 117, Issue:6

    Topics: Adolescent; Adult; Age of Onset; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Enzyme Inhibitors; Farnesyltranstransferase; Humans; Idarubicin; Leukemia, Myeloid, Acute; Middle Aged; Myelodysplastic Syndromes; Neoadjuvant Therapy; Neoplasm Staging; Quinolones; Remission Induction; Risk; Young Adult

2011
Salvage chemotherapy with low-dose cytarabine and aclarubicin in combination with granulocyte colony-stimulating factor priming in patients with refractory or relapsed acute myeloid leukemia with translocation (8;21).
    Leukemia research, 2011, Volume: 35, Issue:5

    Topics: Aclarubicin; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Child; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance, Neoplasm; Feasibility Studies; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Salvage Therapy; Translocation, Genetic; Young Adult

2011
A randomized comparison of 4 courses of standard-dose multiagent chemotherapy versus 3 courses of high-dose cytarabine alone in postremission therapy for acute myeloid leukemia in adults: the JALSG AML201 Study.
    Blood, 2011, Feb-24, Volume: 117, Issue:8

    Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid, Acute; Leukocyte Count; Middle Aged; Remission Induction; Survival Analysis; Treatment Outcome; Young Adult

2011
Daily palonosetron is superior to ondansetron in the prevention of delayed chemotherapy-induced nausea and vomiting in patients with acute myelogenous leukemia.
    Cancer, 2010, Dec-15, Volume: 116, Issue:24

    Topics: Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Female; Humans; Isoquinolines; Leukemia, Myeloid, Acute; Male; Middle Aged; Nausea; Ondansetron; Palonosetron; Quinuclidines; Serotonin Antagonists; Vomiting

2010
FLT3-internal tandem duplication and age are the major prognostic factors in patients with relapsed acute myeloid leukemia with normal karyotype.
    Haematologica, 2011, Volume: 96, Issue:5

    Topics: Adolescent; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; fms-Like Tyrosine Kinase 3; Follow-Up Studies; Gene Duplication; Humans; Kaplan-Meier Estimate; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Multivariate Analysis; Nucleophosmin; Prognosis; Recurrence; Stem Cell Transplantation; Tandem Repeat Sequences; Transplantation, Homologous; Treatment Outcome; Young Adult

2011
Report of a phase II study of clofarabine and cytarabine in de novo and relapsed and refractory AML patients and in selected elderly patients at high risk for anthracycline toxicity.
    The oncologist, 2011, Volume: 16, Issue:2

    Topics: Adenine Nucleotides; Adult; Aged; Aged, 80 and over; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cytarabine; Disease-Free Survival; Drug Administration Schedule; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Middle Aged; Neoplasm Recurrence, Local; Patient Selection; Recurrence; Remission Induction; Survival Analysis; Treatment Outcome

2011
First-in-man study of CPX-351: a liposomal carrier containing cytarabine and daunorubicin in a fixed 5:1 molar ratio for the treatment of relapsed and refractory acute myeloid leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Mar-10, Volume: 29, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Liposomes; Male; Maximum Tolerated Dose; Middle Aged; Myelodysplastic Syndromes; Recurrence; Salvage Therapy; Treatment Outcome; Young Adult

2011
Early allo-SCT for AML with a complex aberrant karyotype--results from a prospective pilot study.
    Bone marrow transplantation, 2012, Volume: 47, Issue:1

    Topics: Abnormal Karyotype; Acute Disease; Adolescent; Adult; Amsacrine; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Disease-Free Survival; Female; Follow-Up Studies; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Lymphocyte Depletion; Male; Middle Aged; Pilot Projects; Prospective Studies; Survival Rate; Transplantation Conditioning; Transplantation, Homologous; Vidarabine

2012
Cytarabine dose for acute myeloid leukemia.
    The New England journal of medicine, 2011, Mar-17, Volume: 364, Issue:11

    Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Combined Modality Therapy; Cytarabine; Female; Humans; Intention to Treat Analysis; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Proportional Hazards Models; Remission Induction; Stem Cell Transplantation; Survival Analysis; Young Adult

2011
Prophylactic treatment for cytosine arabinoside-induced keratoconjunctivitis.
    International ophthalmology, 2011, Volume: 31, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cytarabine; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Glucocorticoids; Humans; Immunosuppressive Agents; Keratoconjunctivitis; Leukemia, Myeloid, Acute; Male; Middle Aged; Ophthalmic Solutions; Prednisolone; Treatment Outcome; Young Adult

2011
Influence of anticancer therapy on oxidation phenotype and acetylation phenotype in patients with acute myeloblastic leukemia.
    Pharmacological reports : PR, 2011, Volume: 63, Issue:1

    Topics: Acetylation; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Cytochrome P-450 CYP2D6; Daunorubicin; Drug Interactions; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Oxidation-Reduction; Phenotype; Young Adult

2011
Phase 1 study of arsenic trioxide, high-dose cytarabine, and idarubicin to down-regulate constitutive signal transducer and activator of transcription 3 activity in patients aged <60 years with acute myeloid leukemia.
    Cancer, 2011, Nov-01, Volume: 117, Issue:21

    Topics: Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Cytarabine; Down-Regulation; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Oxides; STAT3 Transcription Factor

2011
Hematologic improvement and response in elderly AML/RAEB patients treated with valproic acid and low-dose Ara-C.
    Leukemia research, 2011, Volume: 35, Issue:8

    Topics: Aged; Aged, 80 and over; Anemia, Refractory, with Excess of Blasts; Anticonvulsants; Antimetabolites, Antineoplastic; Cytarabine; Drug Therapy, Combination; Feasibility Studies; Female; Follow-Up Studies; Humans; In Situ Hybridization, Fluorescence; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Recurrence, Local; Remission Induction; Survival Rate; Treatment Outcome; Valproic Acid

2011
The addition of arsenic trioxide to low-dose Ara-C in older patients with AML does not improve outcome.
    Leukemia, 2011, Volume: 25, Issue:7

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Chemical and Drug Induced Liver Injury; Comorbidity; Cytarabine; Disease-Free Survival; Early Termination of Clinical Trials; Female; Gastrointestinal Diseases; Heart Diseases; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Male; Middle Aged; Oxides; Remission Induction; Treatment Outcome

2011
Continuous and high-dose cytarabine combined chemotherapy in children with down syndrome and acute myeloid leukemia: Report from the Japanese children's cancer and leukemia study group (JCCLSG) AML 9805 down study.
    Pediatric blood & cancer, 2011, Jul-15, Volume: 57, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Cytarabine; Disease-Free Survival; Down Syndrome; Doxorubicin; Female; Humans; Infant; Infant, Newborn; Japan; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Survival Rate; Vincristine

2011
Cytarabine dose of 36 g/m² compared with 12 g/m² within first consolidation in acute myeloid leukemia: results of patients enrolled onto the prospective randomized AML96 study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Jul-01, Volume: 29, Issue:19

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Cytogenetics; Disease-Free Survival; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Proportional Hazards Models; Prospective Studies; Remission Induction; Risk; Treatment Outcome

2011
Comparison of high-dose cytarabine and timed-sequential chemotherapy as consolidation for younger adults with AML in first remission: the ALFA-9802 study.
    Blood, 2011, Aug-18, Volume: 118, Issue:7

    Topics: Adolescent; Adult; Age Factors; Antimetabolites, Antineoplastic; Cytarabine; Cytogenetic Analysis; Disease-Free Survival; Drug Therapy; Humans; Leukemia, Myeloid, Acute; Middle Aged; Nucleophosmin; Prospective Studies; Remission Induction; Young Adult

2011
Phase 2 randomized study of p53 antisense oligonucleotide (cenersen) plus idarubicin with or without cytarabine in refractory and relapsed acute myeloid leukemia.
    Cancer, 2012, Jan-15, Volume: 118, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Genes, p53; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Oligonucleotides; Oligonucleotides, Antisense; Recurrence; Treatment Failure

2012
Proteasome inhibition in myelodysplastic syndromes and acute myelogenous leukemia cell lines.
    Cancer investigation, 2011, Volume: 29, Issue:7

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Azacitidine; Benzenesulfonates; Boronic Acids; Bortezomib; Cell Line, Tumor; Cell Proliferation; Cytarabine; Cytokines; Farnesyltranstransferase; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Niacinamide; Oxides; Phenylurea Compounds; Protease Inhibitors; Proteasome Inhibitors; Pyrazines; Pyridines; Sorafenib

2011
Phase I pharmacokinetic and pharmacodynamic study of the multikinase inhibitor sorafenib in combination with clofarabine and cytarabine in pediatric relapsed/refractory leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Aug-20, Volume: 29, Issue:24

    Topics: Adenine Nucleotides; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Benzenesulfonates; Child; Clofarabine; Cytarabine; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Recurrence; Sorafenib

2011
Induction therapy of AML with ara-C plus daunorubicin versus ara-C plus gemtuzumab ozogamicin: a randomized phase II trial in elderly patients.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2012, Volume: 23, Issue:4

    Topics: Aged; Aged, 80 and over; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Gemtuzumab; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Survival Analysis; Treatment Outcome

2012
Clofarabine with high dose cytarabine and granulocyte colony-stimulating factor (G-CSF) priming for relapsed and refractory acute myeloid leukaemia.
    British journal of haematology, 2011, Volume: 155, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemical and Drug Induced Liver Injury; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Infections; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Maximum Tolerated Dose; Middle Aged; Proportional Hazards Models; Recurrence; Remission Induction; Risk; Salvage Therapy; Young Adult

2011
Cytoreductive treatment with clofarabine/ara-C combined with reduced-intensity conditioning and allogeneic stem cell transplantation in patients with high-risk, relapsed, or refractory acute myeloid leukemia and advanced myelodysplastic syndrome.
    European journal of haematology, 2012, Volume: 88, Issue:1

    Topics: Adenine Nucleotides; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cyclosporine; Cytarabine; Disease-Free Survival; Female; Graft vs Host Disease; Humans; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Male; Middle Aged; Mycophenolic Acid; Myelodysplastic Syndromes; Retrospective Studies; Stem Cell Transplantation; Survival Rate; Transplantation Conditioning; Transplantation, Homologous

2012
Results of a randomized trial in children with Acute Myeloid Leukaemia: medical research council AML12 trial.
    British journal of haematology, 2011, Volume: 155, Issue:3

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Humans; Induction Chemotherapy; Infant; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Prognosis; Survival Analysis; Thioguanine; Treatment Outcome

2011
Upfront allogeneic blood stem cell transplantation for patients with high-risk myelodysplastic syndrome or secondary acute myeloid leukemia using a FLAMSA-based high-dose sequential conditioning regimen.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2012, Volume: 18, Issue:3

    Topics: Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cyclophosphamide; Cytarabine; Disease-Free Survival; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Melphalan; Middle Aged; Myelodysplastic Syndromes; Transplantation Conditioning; Transplantation, Homologous; Unrelated Donors; Vidarabine

2012
The T_T genotype within the NME1 promoter single nucleotide polymorphism -835 C/T is associated with an increased risk of cytarabine induced neurotoxicity in patients with acute myeloid leukemia.
    Leukemia & lymphoma, 2012, Volume: 53, Issue:5

    Topics: Acetylcysteine; Adolescent; Adult; Aged; Apoptosis; Cytarabine; Female; Genotype; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neurons; Neurotoxicity Syndromes; NM23 Nucleoside Diphosphate Kinases; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Retrospective Studies; Survival Rate; Young Adult

2012
[Clinical study on combination of homoharringtonine, Ara-C and idarubicin induction for treatment of newly diagnosed acute myeloid leukemia patients].
    Zhongguo shi yan xue ye xue za zhi, 2011, Volume: 19, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Harringtonines; Homoharringtonine; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Young Adult

2011
Fractionated doses of gemtuzumab ozogamicin with escalated doses of daunorubicin and cytarabine as first acute myeloid leukemia salvage in patients aged 50-70-year old: a phase 1/2 study of the acute leukemia French association.
    American journal of hematology, 2012, Volume: 87, Issue:1

    Topics: Aged; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Salvage Therapy; Treatment Outcome

2012
Valproic acid combined with cytosine arabinoside in elderly patients with acute myeloid leukemia has in vitro but limited clinical activity.
    Leukemia & lymphoma, 2012, Volume: 53, Issue:6

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cell Proliferation; Cytarabine; Drug Evaluation, Preclinical; Female; Humans; Leukemia, Myeloid, Acute; Male; Primary Cell Culture; Treatment Outcome; Tumor Cells, Cultured; Valproic Acid

2012
Single-cell pharmacodynamic monitoring of S6 ribosomal protein phosphorylation in AML blasts during a clinical trial combining the mTOR inhibitor sirolimus and intensive chemotherapy.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Mar-15, Volume: 18, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Phosphorylation; Pilot Projects; Ribosomal Protein S6; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases

2012
Prediction of post-remission survival in acute myeloid leukaemia: a post-hoc analysis of the AML96 trial.
    The Lancet. Oncology, 2012, Volume: 13, Issue:2

    Topics: Adolescent; Adult; Age Factors; Antigens, CD34; Chromosome Aberrations; Cytarabine; Female; fms-Like Tyrosine Kinase 3; Hematopoietic Stem Cell Transplantation; Humans; Karyotype; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Survival Analysis; Transplantation, Homologous; Treatment Outcome

2012
Population pharmacokinetics of cytarabine, etoposide, and daunorubicin in the treatment for acute myeloid leukemia.
    Cancer chemotherapy and pharmacology, 2012, Volume: 69, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Body Surface Area; Chromatography, High Pressure Liquid; Creatinine; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Models, Biological; Nonlinear Dynamics; Prospective Studies; Tissue Distribution; Young Adult

2012
Elacytarabine, a novel 5'-elaidic acid derivative of cytarabine, and idarubicin combination is active in refractory acute myeloid leukemia.
    Leukemia research, 2012, Volume: 36, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Cytarabine; Female; Half-Life; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Maximum Tolerated Dose; Middle Aged; Young Adult

2012
Phase 1 trial of linifanib (ABT-869) in patients with refractory or relapsed acute myeloid leukemia.
    Leukemia & lymphoma, 2012, Volume: 53, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; fms-Like Tyrosine Kinase 3; Humans; Indazoles; Leukemia, Myeloid, Acute; Male; Middle Aged; Phenylurea Compounds; Recurrence; Treatment Outcome

2012
Clofarabine plus low-dose cytarabine followed by clofarabine plus low-dose cytarabine alternating with decitabine in acute myeloid leukemia frontline therapy for older patients.
    Cancer, 2012, Sep-15, Volume: 118, Issue:18

    Topics: Adenine Nucleotides; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Azacitidine; Clofarabine; Consolidation Chemotherapy; Cytarabine; Decitabine; Female; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Treatment Outcome

2012
A randomized comparison of modified intermediate-dose Ara-C versus high-dose ara-c in post-remission therapy for acute myeloid leukemia.
    Anticancer research, 2012, Volume: 32, Issue:2

    Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Consolidation Chemotherapy; Cytarabine; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Mitoxantrone; Prospective Studies; Remission Induction; Vinblastine; Vincristine; Young Adult

2012
A phase 1/2 study of chemosensitization with the CXCR4 antagonist plerixafor in relapsed or refractory acute myeloid leukemia.
    Blood, 2012, Apr-26, Volume: 119, Issue:17

    Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Antineoplastic Combined Chemotherapy Protocols; Benzylamines; Cyclams; Cytarabine; Drug Resistance, Neoplasm; Etoposide; Female; Flow Cytometry; Heterocyclic Compounds; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Neoplasm Recurrence, Local; Prognosis; Receptors, CXCR4; Remission Induction; Salvage Therapy; Survival Rate; Young Adult

2012
[CAG-GO therapy for patients with relapsed or primary refractory CD33-positive acute myelogenous leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2012, Volume: 53, Issue:1

    Topics: Aclarubicin; Aged; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Gemtuzumab; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Remission Induction; Sialic Acid Binding Ig-like Lectin 3; Survival Rate

2012
Disease-stabilizing treatment with all-trans retinoic acid and valproic acid in acute myeloid leukemia: serum hsp70 and hsp90 levels and serum cytokine profiles are determined by the disease, patient age, and anti-leukemic treatment.
    American journal of hematology, 2012, Volume: 87, Issue:4

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Cytokines; Female; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Male; Middle Aged; Neoplasm Proteins; Palliative Care; Prognosis; Theophylline; Tretinoin; Tumor Cells, Cultured; Valproic Acid

2012
Favorable effect of priming with granulocyte colony-stimulating factor in remission induction of acute myeloid leukemia restricted to dose escalation of cytarabine.
    Blood, 2012, Jun-07, Volume: 119, Issue:23

    Topics: Adult; Antimetabolites, Antineoplastic; Cytarabine; Disease-Free Survival; Female; Granulocyte Colony-Stimulating Factor; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Remission Induction; Treatment Outcome

2012
Cladribine, but not fludarabine, added to daunorubicin and cytarabine during induction prolongs survival of patients with acute myeloid leukemia: a multicenter, randomized phase III study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jul-10, Volume: 30, Issue:20

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Survival Analysis; Vidarabine; Young Adult

2012
Twice-daily fludarabine and cytarabine combination with or without gentuzumab ozogamicin is effective in patients with relapsed/refractory acute myeloid leukemia, high-risk myelodysplastic syndrome, and blast- phase chronic myeloid leukemia.
    Clinical lymphoma, myeloma & leukemia, 2012, Volume: 12, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Cytarabine; Disease-Free Survival; Gemtuzumab; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Middle Aged; Myelodysplastic Syndromes; Prognosis; Recurrence; Remission Induction; Risk Factors; Survival Analysis; Vidarabine; Young Adult

2012
High Dose Cytosine Arabinoside in the consolidation of adult acute myeloid leukemia.
    Mymensingh medical journal : MMJ, 2012, Volume: 21, Issue:2

    Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Consolidation Chemotherapy; Cytarabine; Disease-Free Survival; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Young Adult

2012
Bortezomib combined with low-dose cytarabine in Intermediate-2 and high risk myelodysplastic syndromes. A phase I/II Study by the GFM.
    British journal of haematology, 2012, Volume: 158, Issue:2

    Topics: Aged; Aged, 80 and over; Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Bortezomib; Cytarabine; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Pyrazines; Survival Analysis; Treatment Outcome

2012
Clofarabine plus cytarabine compared with cytarabine alone in older patients with relapsed or refractory acute myelogenous leukemia: results from the CLASSIC I Trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jul-10, Volume: 30, Issue:20

    Topics: Adenine Nucleotides; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cytarabine; Disease-Free Survival; Double-Blind Method; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Placebos; Recurrence

2012
The addition of the farnesyl transferase inhibitor, tipifarnib, to low dose cytarabine does not improve outcome for older patients with AML.
    British journal of haematology, 2012, Volume: 158, Issue:4

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Enzyme Inhibitors; Farnesyltranstransferase; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Quinolones; Survival Analysis; Treatment Outcome

2012
Treatment outcome in older patients with childhood acute myeloid leukemia.
    Cancer, 2012, Dec-15, Volume: 118, Issue:24

    Topics: Adolescent; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cladribine; Combined Modality Therapy; Cytarabine; Etoposide; Female; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Survival Rate; Transplantation, Autologous; Young Adult

2012
Multicenter, randomized, open-label, phase III trial of decitabine versus patient choice, with physician advice, of either supportive care or low-dose cytarabine for the treatment of older patients with newly diagnosed acute myeloid leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jul-20, Volume: 30, Issue:21

    Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Choice Behavior; Cytarabine; Decision Making; Decitabine; Drug Administration Schedule; Female; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Neutropenia; Palliative Care; Patient Participation; Remission Induction; Risk Assessment; Risk Factors; Thrombocytopenia; Treatment Outcome

2012
Elacytarabine has single-agent activity in patients with advanced acute myeloid leukaemia.
    British journal of haematology, 2012, Volume: 158, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Cytarabine; Female; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged; Referral and Consultation; Remission Induction; Risk Factors; Stem Cell Transplantation; Survival Rate; Treatment Outcome

2012
Mutations in the DNMT3A exon 23 independently predict poor outcome in older patients with acute myeloid leukemia: a SWOG report.
    Leukemia, 2013, Volume: 27, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; Etoposide; Exons; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Mutation; Neoplasm Staging; Prognosis; Survival Rate

2013
[The clinical comparison of FLAG regimen versus IA regimen for newly diagnosed acute myeloid leukemia].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2012, Volume: 33, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Treatment Outcome; Vidarabine; Young Adult

2012
Randomized phase II study of two schedules of flavopiridol given as timed sequential therapy with cytosine arabinoside and mitoxantrone for adults with newly diagnosed, poor-risk acute myelogenous leukemia.
    Haematologica, 2012, Volume: 97, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; Flavonoids; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Piperidines; Survival Rate

2012
High-dose cytarabine (24 g/m2) in combination with idarubicin (HiDAC-3) results in high first-cycle response with limited gastrointestinal toxicity in adult acute myeloid leukaemia.
    Internal medicine journal, 2013, Volume: 43, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Gastrointestinal Tract; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Retrospective Studies; Treatment Outcome; Young Adult

2013
Randomized phase IIb study of low-dose cytarabine and lintuzumab versus low-dose cytarabine and placebo in older adults with untreated acute myeloid leukemia.
    Haematologica, 2013, Volume: 98, Issue:1

    Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Double-Blind Method; Female; Humans; Internationality; Leukemia, Myeloid, Acute; Male; Middle Aged; Survival Rate; Treatment Outcome

2013
Retrospective comparison of clofarabine versus fludarabine in combination with high-dose cytarabine with or without granulocyte colony-stimulating factor as salvage therapies for acute myeloid leukemia.
    Haematologica, 2013, Volume: 98, Issue:1

    Topics: Adenine Nucleotides; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Middle Aged; Retrospective Studies; Salvage Therapy; Survival Rate; Treatment Outcome; Vidarabine; Young Adult

2013
Predictors and short-term outcomes of hyperleukocytosis in children with acute myeloid leukemia: a report from the Children's Oncology Group.
    Haematologica, 2012, Volume: 97, Issue:11

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Humans; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Leukocytosis; Male; Survival Rate

2012
Addition of gemtuzumab ozogamicin to induction chemotherapy improves survival in older patients with acute myeloid leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Nov-10, Volume: 30, Issue:32

    Topics: Adenine Nucleotides; Aged; Aged, 80 and over; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Gemtuzumab; Humans; Immunotoxins; Incidence; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Odds Ratio; Remission Induction; Secondary Prevention; Treatment Outcome

2012
Sequential arabinosylcytosin with or without fludarabine in paracmastic patients with acute myeloid leukemia.
    Die Pharmazie, 2012, Volume: 67, Issue:7

    Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents; Area Under Curve; Chromatography, High Pressure Liquid; Cytarabine; Drug Interactions; Drug Therapy, Combination; Female; Humans; Indicators and Reagents; Injections, Intravenous; Leukemia, Myeloid, Acute; Male; Vidarabine

2012
Clinical outcome of treatment with a combined regimen of decitabine and aclacinomycin/cytarabine for patients with refractory acute myeloid leukemia.
    Annals of hematology, 2012, Volume: 91, Issue:12

    Topics: Aclarubicin; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cell Survival; Cyclin-Dependent Kinase Inhibitor p15; Cytarabine; Decitabine; DNA Methylation; DNA Modification Methylases; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Humans; Leukemia, Myeloid, Acute; Leukocytes, Mononuclear; Male; Middle Aged; Recurrence; Remission Induction; Survival Analysis; Tumor Cells, Cultured; Young Adult

2012
Phase 1 trial of gemtuzumab ozogamicin in combination with enocitabine and daunorubicin for elderly patients with relapsed or refractory acute myeloid leukemia: Japan Adult Leukemia Study Group (JALSG)-GML208 study.
    International journal of hematology, 2012, Volume: 96, Issue:4

    Topics: Aged; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Gemtuzumab; Humans; Japan; Leukemia, Myeloid, Acute; Male; Neoplasm Staging; Recurrence; Treatment Outcome

2012
The addition of gemtuzumab ozogamicin to low-dose Ara-C improves remission rate but does not significantly prolong survival in older patients with acute myeloid leukaemia: results from the LRF AML14 and NCRI AML16 pick-a-winner comparison.
    Leukemia, 2013, Volume: 27, Issue:1

    Topics: Aged; Aged, 80 and over; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Grading; Prognosis; Remission Induction; Survival Rate

2013
Acute Myeloid Leukemia (AML): different treatment strategies versus a common standard arm--combined prospective analysis by the German AML Intergroup.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Oct-10, Volume: 30, Issue:29

    Topics: Adolescent; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Confidence Intervals; Cytarabine; Daunorubicin; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Germany; Humans; Infusions, Intravenous; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Proportional Hazards Models; Prospective Studies; Risk Assessment; Severity of Illness Index; Sex Factors; Survival Analysis; Treatment Outcome; Young Adult

2012
[The first results of treatment for adult acute myeloid leukemia according to the AML-01.10 protocol of the Research Group of the Hematology Centers of Russia].
    Terapevticheskii arkhiv, 2012, Volume: 84, Issue:7

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Remission Induction; Russia; Time Factors; Transplantation, Homologous; Treatment Outcome; Young Adult

2012
A phase I/II study of sorafenib in combination with low dose cytarabine in elderly patients with acute myeloid leukemia or high-risk myelodysplastic syndrome from the National Cancer Institute of Canada Clinical Trials Group: trial IND.186.
    Leukemia & lymphoma, 2013, Volume: 54, Issue:4

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Myelodysplastic Syndromes; Niacinamide; Phenylurea Compounds; Sorafenib; Treatment Outcome

2013
Fludarabine, cytarabine, and attenuated-dose idarubicin (m-FLAI) combination therapy for elderly acute myeloid leukemia patients.
    American journal of hematology, 2013, Volume: 88, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cohort Studies; Cytarabine; Disease-Free Survival; Female; Gene Expression Regulation, Leukemic; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Proto-Oncogene Proteins c-kit; Survival Rate; Time Factors; Vidarabine

2013
Pretreatment prognostic factors for overall survival in primary resistant acute myeloid leukemia.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2012, Volume: 66, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Blood Cell Count; Bone Marrow Cells; Comorbidity; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Resistance, Neoplasm; Etoposide; Female; Hemoglobins; Humans; Immunophenotyping; Kaplan-Meier Estimate; Karyotyping; Kidney Function Tests; Leukemia, Myeloid, Acute; Liver Function Tests; Logistic Models; Male; Middle Aged; Prognosis; Remission Induction; Risk Factors; Treatment Outcome

2012
Phase I and pharmacologic trial of cytosine arabinoside with the selective checkpoint 1 inhibitor Sch 900776 in refractory acute leukemias.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Dec-15, Volume: 18, Issue:24

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Checkpoint Kinase 1; Cytarabine; Drug Resistance, Neoplasm; Female; Histones; Humans; Leukemia, Myeloid, Acute; Male; Maximum Tolerated Dose; Middle Aged; Phosphorylation; Protein Kinases; Protein Processing, Post-Translational; Pyrazoles; Pyrimidines; Treatment Outcome; Young Adult

2012
Bortezomib added to daunorubicin and cytarabine during induction therapy and to intermediate-dose cytarabine for consolidation in patients with previously untreated acute myeloid leukemia age 60 to 75 years: CALGB (Alliance) study 10502.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Mar-01, Volume: 31, Issue:7

    Topics: Aged; Antigens, Differentiation, B-Lymphocyte; Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Bortezomib; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Administration Schedule; Drug Synergism; Female; Follow-Up Studies; Histocompatibility Antigens Class II; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Peripheral Nervous System; Pyrazines; Remission Induction; Survival Analysis; Treatment Outcome

2013
Fludarabine and cytarabine in patients with relapsed acute myeloid leukemia refractory to initial salvage therapy.
    International journal of hematology, 2012, Volume: 96, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemical and Drug Induced Liver Injury; Cytarabine; Etoposide; Female; Gastrointestinal Diseases; Hematologic Diseases; Humans; Karyotype; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Neoplasms, Second Primary; Recurrence; Remission Induction; Salvage Therapy; Vidarabine

2012
Cytarabine and clofarabine after high-dose cytarabine in relapsed or refractory AML patients.
    American journal of hematology, 2012, Volume: 87, Issue:12

    Topics: Adenine Nucleotides; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Remission Induction; Treatment Outcome; Young Adult

2012
High frequency of streptococcal bacteraemia during childhood AML therapy irrespective of dose of cytarabine.
    Pediatric blood & cancer, 2013, Volume: 60, Issue:7

    Topics: Adolescent; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bacteremia; Child; Child, Preschool; Cytarabine; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Streptococcal Infections; Viridans Streptococci

2013
Feasibility of azacitidine added to standard chemotherapy in older patients with acute myeloid leukemia--a randomised SAL pilot study.
    PloS one, 2012, Volume: 7, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Feasibility Studies; Female; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Maximum Tolerated Dose; Middle Aged; Pilot Projects; Survival Analysis; Treatment Outcome

2012
Improved outcome in pediatric relapsed acute myeloid leukemia: results of a randomized trial on liposomal daunorubicin by the International BFM Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Feb-10, Volume: 31, Issue:5

    Topics: Adolescent; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Confounding Factors, Epidemiologic; Cytarabine; Daunorubicin; Female; Granulocyte Colony-Stimulating Factor; Humans; International Cooperation; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Liposomes; Male; Odds Ratio; Remission Induction; Research Design; Treatment Outcome; Vidarabine

2013
Prospective evaluation of gene mutations and minimal residual disease in patients with core binding factor acute myeloid leukemia.
    Blood, 2013, Mar-21, Volume: 121, Issue:12

    Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Core Binding Factors; Cytarabine; DNA Mutational Analysis; Drug Resistance, Neoplasm; Female; Genes, Neoplasm; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Neoplasm, Residual; Prognosis; Prospective Studies; Treatment Outcome; Young Adult

2013
A phase Ib GOELAMS study of the mTOR inhibitor RAD001 in association with chemotherapy for AML patients in first relapse.
    Leukemia, 2013, Volume: 27, Issue:7

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Everolimus; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases; Treatment Outcome; Young Adult

2013
High-dose cytarabine-based consolidation shows superior results for older AML patients with intermediate risk cytogenetics in first complete remission.
    Leukemia research, 2013, Volume: 37, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Follow-Up Studies; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Retrospective Studies; Risk Factors; Survival Rate

2013
Safety and pharmacokinetics of the antisense oligonucleotide (ASO) LY2181308 as a single-agent or in combination with idarubicin and cytarabine in patients with refractory or relapsed acute myeloid leukemia (AML).
    Investigational new drugs, 2013, Volume: 31, Issue:4

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Demography; Female; Humans; Idarubicin; Inhibitor of Apoptosis Proteins; Leukemia, Myeloid, Acute; Male; Middle Aged; Oligonucleotides; Oligonucleotides, Antisense; Recurrence; Survivin; Treatment Outcome

2013
Phase 3 study of the multidrug resistance modulator PSC-833 in previously untreated patients 60 years of age and older with acute myeloid leukemia: Cancer and Leukemia Group B Study 9720.
    Blood, 2002, Aug-15, Volume: 100, Issue:4

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cyclosporins; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Resistance, Multiple; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Logistic Models; Male; Middle Aged; Remission Induction

2002
Long-term follow-up of patients >or=60 yr old with acute myeloid leukaemia treated with intensive chemotherapy.
    European journal of haematology, 2002, Volume: 68, Issue:6

    Topics: Aclarubicin; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Middle Aged; Survival Rate; Thioguanine; Time Factors

2002
Interim comparison of a continuous infusion versus a short daily infusion of cytarabine given in combination with cladribine for pediatric acute myeloid leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Oct-15, Volume: 20, Issue:20

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Bone Marrow; Child; Child, Preschool; Cladribine; Cytarabine; Daunorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Remission Induction

2002
Timed sequential therapy of acute myelogenous leukemia in adults: a phase II study of retinoids in combination with the sequential administration of cytosine arabinoside, idarubicin and etoposide.
    Leukemia research, 2003, Volume: 27, Issue:4

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Etoposide; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Risk Factors; Survival Analysis; Treatment Outcome; Tretinoin

2003
A randomized trial of liposomal daunorubicin and cytarabine versus liposomal daunorubicin and topotecan with or without thalidomide as initial therapy for patients with poor prognosis acute myelogenous leukemia or myelodysplastic syndrome.
    Cancer, 2003, Mar-01, Volume: 97, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Endothelial Growth Factors; Humans; Intercellular Signaling Peptides and Proteins; Leukemia, Myeloid, Acute; Liposomes; Lymphokines; Middle Aged; Myelodysplastic Syndromes; Neovascularization, Pathologic; Prognosis; Survival Analysis; Thalidomide; Topotecan; Treatment Outcome; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2003
Gemtuzumab, fludarabine, cytarabine, and cyclosporine in patients with newly diagnosed acute myelogenous leukemia or high-risk myelodysplastic syndromes.
    Cancer, 2003, Mar-15, Volume: 97, Issue:6

    Topics: Adult; Aged; Alanine Transaminase; Aminoglycosides; Anemia, Refractory, with Excess of Blasts; Anti-Bacterial Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Aspartate Aminotransferases; Cyclosporine; Cytarabine; Female; Gemtuzumab; Humans; Hyperbilirubinemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Survival; Treatment Outcome; Vidarabine

2003
Randomized phase I/II study of troxacitabine combined with cytarabine, idarubicin, or topotecan in patients with refractory myeloid leukemias.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Mar-15, Volume: 21, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Cytosine; Dioxolanes; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Idarubicin; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Topotecan; Treatment Outcome

2003
Comparison of allogeneic stem cell transplantation, high-dose cytarabine, and autologous peripheral stem cell transplantation as postremission treatment in patients with de novo acute myelogenous leukemia.
    Cancer, 2003, Apr-01, Volume: 97, Issue:7

    Topics: Adolescent; Adult; Cytarabine; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Stem Cell Transplantation; Survival Analysis; Transplantation Conditioning; Transplantation, Autologous; Transplantation, Homologous; Treatment Outcome

2003
Quinine as a multidrug resistance inhibitor: a phase 3 multicentric randomized study in adult de novo acute myelogenous leukemia.
    Blood, 2003, Aug-15, Volume: 102, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytarabine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Prospective Studies; Quinine; Rhodamine 123

2003
FLAG-IDA in the treatment of refractory/relapsed acute myeloid leukemia: single-center experience.
    Annals of hematology, 2003, Volume: 82, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Treatment Outcome; Vidarabine

2003
A homoharringtonine-based regimen for childhood acute myelogenous leukemia.
    Medical and pediatric oncology, 2003, Volume: 41, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; China; Cytarabine; Disease-Free Survival; Etoposide; Female; Harringtonines; Homoharringtonine; Humans; Leukemia, Myeloid, Acute; Male; Neoplasm Recurrence, Local; Survival Analysis; Treatment Outcome

2003
Pilot study of gemtuzumab ozogamicin, liposomal daunorubicin, cytarabine and cyclosporine regimen in patients with refractory acute myelogenous leukemia.
    Leukemia research, 2003, Volume: 27, Issue:10

    Topics: Adolescent; Adult; Aged; Aminoglycosides; Anti-Bacterial Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cyclosporine; Cytarabine; Daunorubicin; Female; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Liposomes; Male; Middle Aged; Pilot Projects; Remission Induction; Salvage Therapy; Treatment Outcome

2003
Mitoxantrone and cytarabine induction, high-dose cytarabine, and etoposide intensification for pediatric patients with relapsed or refractory acute myeloid leukemia: Children's Cancer Group Study 2951.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Aug-01, Volume: 21, Issue:15

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Drug Administration Schedule; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Prognosis; Survival Rate; Treatment Outcome

2003
Salvage by timed sequential chemotherapy in primary resistant acute myeloid leukemia: analysis of prognostic factors.
    Annals of hematology, 2003, Volume: 82, Issue:11

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Mitoxantrone; Neoplasm Recurrence, Local; Prognosis; Remission Induction; Salvage Therapy; Survival Rate

2003
A multicenter, open, non-comparative, phase II study of the combination of cladribine (2-chlorodeoxyadenosine), cytarabine, and G-CSF as induction therapy in refractory acute myeloid leukemia - a report of the Polish Adult Leukemia Group (PALG).
    European journal of haematology, 2003, Volume: 71, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cytarabine; Disease-Free Survival; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Prognosis; Recurrence; Remission Induction; Survival Rate

2003
Effect of priming with granulocyte colony-stimulating factor on the outcome of chemotherapy for acute myeloid leukemia.
    The New England journal of medicine, 2003, Aug-21, Volume: 349, Issue:8

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Remission Induction; Survival Analysis

2003
Apoptosis induction in peripheral leukemia cells by remission induction treatment in vivo: selective depletion and apoptosis in a CD34+ subpopulation of leukemia cells.
    Leukemia, 2003, Volume: 17, Issue:11

    Topics: Adult; Antigens, CD; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Child; Cytarabine; Etoposide; fas Receptor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Leukocyte Count; Leukocytes, Mononuclear; Lymphocyte Depletion; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Treatment Outcome

2003
[Modified FLAG regimen in the management of refractory acute myeloid leukemia].
    Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA, 2003, Volume: 23, Issue:10

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Vidarabine

2003
Mitoxantrone and cytosine arabinoside in previously untreated adult patients with acute non-lymphocytic leukemia.
    Haematologia, 1996, Volume: 27, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Cytarabine; Disease-Free Survival; Female; Gastrointestinal Diseases; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Remission Induction; Treatment Outcome

1996
6-Thioguanine, cytarabine, and daunorubicin (TAD) and high-dose cytarabine and mitoxantrone (HAM) for induction, TAD for consolidation, and either prolonged maintenance by reduced monthly TAD or TAD-HAM-TAD and one course of intensive consolidation by seq
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Dec-15, Volume: 21, Issue:24

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Prognosis; Proportional Hazards Models; Survival Analysis; Thioguanine

2003
[Effect of modified FLAG regimen therapy on 33 patients with relapsed/refractory leukemia].
    Ai zheng = Aizheng = Chinese journal of cancer, 2003, Volume: 22, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Treatment Outcome; Vidarabine

2003
Oral treatment of acute myeloid leukaemia with etoposide, thioguanine, and idarubicin (ETI) in elderly patients: a prospective randomised comparison with intravenous cytarabine, idarubicin, and thioguanine in the second and third treatment cycle.
    European journal of haematology, 2004, Volume: 72, Issue:1

    Topics: Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Etoposide; Female; Humans; Idarubicin; Injections, Intravenous; Leukemia, Myeloid, Acute; Male; Patient Selection; Recurrence; Statistics, Nonparametric; Survival Rate; Thioguanine; Time Factors

2004
Addition of cladribine to daunorubicin and cytarabine increases complete remission rate after a single course of induction treatment in acute myeloid leukemia. Multicenter, phase III study.
    Leukemia, 2004, Volume: 18, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Treatment Outcome

2004
Risk-adapted induction and consolidation therapy in adults with de novo AML aged
    Annals of hematology, 2004, Volume: 83, Issue:6

    Topics: Adolescent; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Idarubicin; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Prospective Studies; Remission Induction; Risk Assessment; Stem Cell Transplantation; Survival Analysis

2004
The value of fludarabine in addition to ARA-C and G-CSF in the treatment of patients with high-risk myelodysplastic syndromes and AML in elderly patients.
    Blood, 2004, Apr-15, Volume: 103, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Cytarabine; Disease-Free Survival; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Hematopoiesis; Humans; In Vitro Techniques; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Prognosis; Recombinant Proteins; Risk Factors; Survival Rate; Vidarabine

2004
A fludarabine, topotecan, and cytarabine regimen is active in patients with refractory acute myelogenous leukemia.
    Leukemia research, 2004, Volume: 28, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Remission Induction; Topotecan; Treatment Outcome; Vidarabine

2004
A phase II study of timed sequential therapy of acute myelogenous leukemia (AML) for patients over the age of 60: two cycle timed sequential therapy with topotecan, ara-C and mitoxantrone in adults with poor-risk AML.
    Leukemia research, 2004, Volume: 28, Issue:6

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Demography; Disease-Free Survival; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Myelodysplastic Syndromes; Remission Induction; Risk Factors; Survival Rate; Topotecan; Treatment Outcome

2004
Priming with GM-CSF for acute myelogenous leukemia (AML): GOELAM data.
    Annals of hematology, 2004, Volume: 83 Suppl 1

    Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Cytarabine; Drug Administration Schedule; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Middle Aged; Recombinant Proteins

2004
Priming with granulocyte colony-stimulating factor--relation to high-dose cytarabine in acute myeloid leukemia.
    The New England journal of medicine, 2004, May-20, Volume: 350, Issue:21

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Stem Cell Transplantation; Survival Analysis; Thioguanine

2004
Targeting vascular endothelial growth factor for relapsed and refractory adult acute myelogenous leukemias: therapy with sequential 1-beta-d-arabinofuranosylcytosine, mitoxantrone, and bevacizumab.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Jun-01, Volume: 10, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineoplastic Agents; Bevacizumab; Cell Line, Tumor; Cell Proliferation; Cytarabine; Disease-Free Survival; Drug Resistance, Neoplasm; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunohistochemistry; Leukemia, Myeloid, Acute; Male; Microcirculation; Middle Aged; Mitoxantrone; Recombinant Proteins; Recurrence; Time Factors; Treatment Outcome; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1

2004
Treatment of primary acute myeloid leukemia: results of a prospective multicenter trial including high-dose cytarabine or stem cell transplantation as post-remission strategy.
    Haematologica, 2004, Volume: 89, Issue:8

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Etoposide; Female; Histocompatibility Testing; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Probability; Prospective Studies; Stem Cell Transplantation; Survival Analysis; Transplantation Conditioning

2004
A randomized trial of continuous infusion versus bolus mitoxantrone in combination with cytarabine in newly diagnosed patients with acute myeloblastic leukemia.
    Hematological oncology, 2004, Volume: 22, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Remission Induction; Time Factors; Treatment Outcome

2004
Peripheral blood stem cell collection after intermediate-dose cytarabine in adult patients with acute myeloblastic leukemia undergoing autologous blood stem cell transplantation in first complete remission.
    International journal of hematology, 2004, Volume: 80, Issue:2

    Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Cytarabine; Female; Humans; Incidence; Leukapheresis; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Siblings; Stem Cell Transplantation; Stem Cells; Tissue and Organ Harvesting; Transplantation Conditioning; Transplantation, Autologous; Treatment Outcome

2004
Clofarabine in adult acute leukemias: clinical success and pharmacokinetics.
    Nucleosides, nucleotides & nucleic acids, 2004, Volume: 23, Issue:8-9

    Topics: Adenine Nucleotides; Adult; Antimetabolites, Antineoplastic; Arabinonucleosides; Clinical Trials as Topic; Clofarabine; Cohort Studies; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Models, Chemical; Myelodysplastic Syndromes; Neoplasm Metastasis; Neoplasms; Nucleosides; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome

2004
Intensified induction chemotherapy in adult acute myeloid leukemia followed by high-dose chemotherapy and autologous peripheral blood stem cell transplantation: an Eastern Cooperative Oncology Group trial (E4995).
    Leukemia & lymphoma, 2005, Volume: 46, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Peripheral Blood Stem Cell Transplantation; Remission Induction; Survival Rate; Transplantation, Autologous; Treatment Outcome

2005
Prognostic features for response and survival in elderly patients with de novo acute myeloid leukemia treated with mitoxantrone and intermediate dose cytarabine.
    Leukemia & lymphoma, 2005, Volume: 46, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Patient Selection; Pilot Projects; Prognosis; Remission Induction; Survival Analysis; Survival Rate; Treatment Outcome

2005
Mini-ICE effectively mobilises peripheral blood stem cells after fludarabine-based regimens in acute myeloid leukaemia.
    European journal of haematology, 2005, Volume: 74, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Hematopoietic Stem Cell Mobilization; Humans; Idarubicin; Leukapheresis; Leukemia, Myeloid, Acute; Male; Middle Aged; Peripheral Blood Stem Cell Transplantation; Transplantation, Autologous; Vidarabine

2005
One versus two high-dose cytarabine-based consolidation before autologous stem cell transplantation for young acute myeloblastic leukaemia patients in first complete remission.
    British journal of haematology, 2005, Volume: 129, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Multivariate Analysis; Recurrence; Remission Induction; Risk Factors; Survival Analysis

2005
High dose intermittent ARA-C (HiDAC) for consolidation of patients with de novo AML: a single center experience.
    Leukemia research, 2005, Volume: 29, Issue:6

    Topics: Adolescent; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Risk Factors; Survival Analysis; Treatment Outcome

2005
Adaptive randomized study of idarubicin and cytarabine alone or with interleukin-11 as induction therapy in patients aged 50 or above with acute myeloid leukemia or high-risk myelodysplastic syndromes.
    Leukemia research, 2005, Volume: 29, Issue:6

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Idarubicin; Interleukin-11; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Risk Factors; Survival Analysis

2005
AML patients with Down syndrome have a high cure rate with AML-BFM therapy with reduced dose intensity.
    Leukemia, 2005, Volume: 19, Issue:8

    Topics: Adolescent; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Disease-Free Survival; Down Syndrome; Etoposide; Female; Humans; Idarubicin; Infant; Leukemia, Megakaryoblastic, Acute; Leukemia, Myeloid, Acute; Male; Survival Rate; Treatment Outcome

2005
Phase III randomized multicenter study of a humanized anti-CD33 monoclonal antibody, lintuzumab, in combination with chemotherapy, versus chemotherapy alone in patients with refractory or first-relapsed acute myeloid leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Jun-20, Volume: 23, Issue:18

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Proportional Hazards Models; Recurrence; Survival Analysis; Treatment Outcome

2005
The value of the MDR1 reversal agent PSC-833 in addition to daunorubicin and cytarabine in the treatment of elderly patients with previously untreated acute myeloid leukemia (AML), in relation to MDR1 status at diagnosis.
    Blood, 2005, Oct-15, Volume: 106, Issue:8

    Topics: Aged; Aged, 80 and over; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporins; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Survival Rate; Treatment Outcome

2005
Severe toxicity following induction chemotherapy for acute myelogenous leukemia in a patient with Werner's syndrome.
    Leukemia & lymphoma, 2005, Volume: 46, Issue:7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; DNA Helicases; Etoposide; Exodeoxyribonucleases; Humans; Leukemia, Myeloid, Acute; Male; Mitoxantrone; RecQ Helicases; Werner Syndrome; Werner Syndrome Helicase

2005
Continuous infusion intermediate-dose cytarabine, mitoxantrone, plus etoposide for refractory or early relapsed acute myelogenous leukemia.
    Leukemia research, 2006, Volume: 30, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Prognosis; Prospective Studies; Salvage Therapy

2006
Phase II trial of amsacrine plus intermediate-dose Ara-C (IDAC) with or without etoposide as salvage therapy for refractory or relapsed acute leukemia.
    Japanese journal of clinical oncology, 2005, Volume: 35, Issue:10

    Topics: Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Diarrhea; Drug Administration Schedule; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Nausea; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Salvage Therapy; Survival Rate; Treatment Outcome; Vomiting, Anticipatory

2005
Combination of tetrandrine as a potential-reversing agent with daunorubicin, etoposide and cytarabine for the treatment of refractory and relapsed acute myelogenous leukemia.
    Leukemia research, 2006, Volume: 30, Issue:4

    Topics: Alkaloids; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzylisoquinolines; Cytarabine; Daunorubicin; Etoposide; Flow Cytometry; Humans; Leukemia, Myeloid, Acute; Recurrence

2006
A randomized, postremission comparison of four courses of standard-dose consolidation therapy without maintenance therapy versus three courses of standard-dose consolidation with maintenance therapy in adults with acute myeloid leukemia: the Japan Adult L
    Cancer, 2005, Dec-15, Volume: 104, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Mitoxantrone; Probability; Remission Induction; Risk Assessment; Treatment Outcome; Vincristine; Vindesine

2005
Pharmacodynamics of cytarabine alone and in combination with 7-hydroxystaurosporine (UCN-01) in AML blasts in vitro and during a clinical trial.
    Blood, 2006, Mar-15, Volume: 107, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blast Crisis; Cell Cycle; Checkpoint Kinase 1; Cyclin-Dependent Kinase 2; Cytarabine; DNA Damage; Humans; JNK Mitogen-Activated Protein Kinases; Leukemia, Myeloid, Acute; Middle Aged; Oncogene Protein v-akt; Pharmacokinetics; Phosphorylation; Pilot Projects; Protein Kinases; Salvage Therapy; Staurosporine; Tumor Cells, Cultured

2006
Phase I and pharmacokinetic study of flavopiridol followed by 1-beta-D-arabinofuranosylcytosine and mitoxantrone in relapsed and refractory adult acute leukemias.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Dec-01, Volume: 11, Issue:23

    Topics: Adult; Aged; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells; Cattle; Cell Proliferation; Cohort Studies; Cytarabine; Endothelium, Vascular; Female; Flavonoids; Humans; Leukemia, Myeloid, Acute; Male; Maximum Tolerated Dose; Middle Aged; Mitoxantrone; Neoplasm Recurrence, Local; Piperidines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Salvage Therapy; U937 Cells; Vascular Endothelial Growth Factor A

2005
Long-term follow-up of high-dose mitoxantrone-based induction therapy for patients with newly-diagnosed acute myelogenous leukemia. Twelve year results from a single institution.
    Leukemia & lymphoma, 2006, Volume: 47, Issue:3

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents; Cytarabine; Diagnosis, Differential; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Remission Induction; Survival Analysis; Treatment Outcome

2006
Fludarabine and cytosine are less effective than standard ADE chemotherapy in high-risk acute myeloid leukemia, and addition of G-CSF and ATRA are not beneficial: results of the MRC AML-HR randomized trial.
    Blood, 2006, Jun-15, Volume: 107, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recombinant Proteins; Remission Induction; Retrospective Studies; Risk Factors; Survival Rate; Treatment Outcome; Tretinoin

2006
Long-term outcome of autologous transplantation of peripheral blood progenitor cells as postremission management of patients > or =60 years with acute myelogenous leukemia.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2006, Volume: 12, Issue:4

    Topics: Aged; Cytarabine; Disease-Free Survival; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Male; Middle Aged; Peripheral Blood Stem Cell Transplantation; Recurrence; Remission Induction; Survival Rate; Transplantation Conditioning; Transplantation, Autologous

2006
Cord blood transplantation for acute myelogenous leukemia using a conditioning regimen consisting of granulocyte colony-stimulating factor-combined high-dose cytarabine, fludarabine, and total body irradiation.
    European journal of haematology, 2006, Volume: 77, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Aspergillosis; Combined Modality Therapy; Cord Blood Stem Cell Transplantation; Cytarabine; Disease-Free Survival; Female; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Sepsis; Stomatitis; Transplantation Conditioning; Vidarabine; Whole-Body Irradiation

2006
Sequential response-adapted induction and consolidation regimens idarubicin/cytarabine and mitoxantrone/etoposide in adult acute myelogenous leukemia: 10 year follow-up of a study by the Canadian Leukemia Studies Group.
    Leukemia & lymphoma, 2006, Volume: 47, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Follow-Up Studies; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Time Factors

2006
Treatment of acute myeloid leukemia patients aged more than 75 years: results of the E-AML-01 trial of the Japanese Elderly Leukemia and Lymphoma Study Group (JELLSG).
    Leukemia & lymphoma, 2006, Volume: 47, Issue:10

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Cytarabine; Disease-Free Survival; Female; Humans; Leukemia, Myeloid, Acute; Male; Remission Induction; Time Factors; Treatment Outcome

2006
Blockade of adaptive defensive changes in cholesterol uptake and synthesis in AML by the addition of pravastatin to idarubicin + high-dose Ara-C: a phase 1 study.
    Blood, 2007, Apr-01, Volume: 109, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cholesterol; Cytarabine; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Pravastatin; Safety

2007
[Multicenter randomized control trial on safety of domestic idarubicin for acute leukemia].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2006, Volume: 28, Issue:9

    Topics: Adolescent; Adult; Aged; Agranulocytosis; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Cyclophosphamide; Cytarabine; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Mucositis; Nausea; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Treatment Outcome; Vincristine

2006
Therapeutic strategy of untreated de novo acute myeloid leukemia in the elderly: the efficacy of continuous drip infusion with low dose cytarabine and etoposide.
    Journal of cancer research and clinical oncology, 2007, Volume: 133, Issue:8

    Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Drug Administration Schedule; Etoposide; Female; Humans; Infusions, Intravenous; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Treatment Outcome

2007
Flexible low-intensity combination chemotherapy for elderly patients with acute myeloid leukaemia: a multicentre, phase II study.
    Drugs & aging, 2007, Volume: 24, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Treatment Outcome

2007
A treatment protocol for infants younger than 1 year with acute lymphoblastic leukaemia (Interfant-99): an observational study and a multicentre randomised trial.
    Lancet (London, England), 2007, Jul-21, Volume: 370, Issue:9583

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Follow-Up Studies; Humans; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone

2007
Sequential flavopiridol, cytosine arabinoside, and mitoxantrone: a phase II trial in adults with poor-risk acute myelogenous leukemia.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Aug-01, Volume: 13, Issue:15 Pt 1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; Flavonoids; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Maximum Tolerated Dose; Middle Aged; Mitoxantrone; Neoplasm Recurrence, Local; Piperidines; Prognosis; Remission Induction; Salvage Therapy; Survival Rate

2007
Amsacrine containing induction therapy in elderly AML patients: comparison to standard induction regimens in a matched-pair analysis.
    Leukemia research, 2008, Volume: 32, Issue:3

    Topics: Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Evaluation; Female; Heart Diseases; Humans; Leukemia, Myeloid, Acute; Male; Matched-Pair Analysis; Middle Aged; Thioguanine

2008
Phase II evaluation of an intensified induction therapy with standard daunomycin and cytarabine followed by high dose cytarabine for adults with previously untreated acute myeloid leukemia: a Southwest Oncology Group study (SWOG-9500).
    American journal of hematology, 2007, Volume: 82, Issue:12

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Ethnicity; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Survival Analysis; Time Factors; Treatment Outcome; United States

2007
Gemtuzumab ozogamicin, cytosine arabinoside, G-CSF combination (G-AraMy) in the treatment of elderly patients with poor-prognosis acute myeloid leukemia.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2008, Volume: 19, Issue:1

    Topics: Aged; Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Cytarabine; Disease-Free Survival; Female; Gemtuzumab; Granulocyte Colony-Stimulating Factor; Humans; Infections; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Male; Neoplasms, Second Primary; Prognosis; Remission Induction; Risk

2008
Adding lomustine to idarubicin and cytarabine for induction chemotherapy in older patients with acute myeloid leukemia: the BGMT 95 trial results.
    Haematologica, 2007, Volume: 92, Issue:10

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Lomustine; Male; Middle Aged; Survival Rate; Treatment Outcome

2007
Phase I trial of FLAGM with high doses of cytosine arabinoside for relapsed, refractory acute myeloid leukemia: study of the Japan Adult Leukemia Study Group (JALSG).
    International journal of hematology, 2007, Volume: 86, Issue:4

    Topics: Adult; Cytarabine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Granulocyte Colony-Stimulating Factor; Humans; Japan; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Recurrence; Vidarabine

2007
A randomized comparison of immediate versus delayed application of G-CSF in induction therapy for patients with acute myeloid leukemia unfit for intensive chemotherapy.
    Haematologica, 2007, Volume: 92, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Prospective Studies; Recombinant Proteins; Retrospective Studies; Time Factors

2007
Daunorubicin, cytarabine and fludarabine (DAF) for remission induction in relapsed or refractory acute myeloid leukemia. Evaluation of safety, tolerance and early outcome--Polish Adult Leukemia Group (PALG) pilot study.
    Annals of hematology, 2008, Volume: 87, Issue:5

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Pilot Projects; Poland; Remission Induction; Vidarabine

2008
Phase I study of the ribonucleotide reductase inhibitor 3-aminopyridine-2-carboxaldehyde-thiosemicarbazone (3-AP) in combination with high dose cytarabine in patients with advanced myeloid leukemia.
    Investigational new drugs, 2008, Volume: 26, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Monitoring; Female; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Maximum Tolerated Dose; Methemoglobinemia; Middle Aged; Pyridines; Recurrence; Thiosemicarbazones

2008
Phase I and pharmacokinetic study of bortezomib in combination with idarubicin and cytarabine in patients with acute myelogenous leukemia.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, Mar-01, Volume: 14, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Boronic Acids; Bortezomib; Cohort Studies; Cytarabine; Female; Gene Expression Profiling; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Recurrence, Local; Oligonucleotide Array Sequence Analysis; Pyrazines; Tissue Distribution; Treatment Outcome

2008
Gemtuzumab ozogamicin plus cytarabine in elderly patients with relapsed or refractory acute myeloid leukaemia.
    British journal of haematology, 2008, Volume: 141, Issue:5

    Topics: Aged; Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Treatment Outcome

2008
Sequential topoisomerase targeting and analysis of mechanisms of resistance to topotecan in patients with acute myelogenous leukemia.
    Anti-cancer drugs, 2008, Volume: 19, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cytarabine; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA-Binding Proteins; Drug Administration Schedule; Drug Resistance, Neoplasm; Etoposide; Female; Gene Expression Regulation, Leukemic; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Neoplasm Proteins; Poly-ADP-Ribose Binding Proteins; Topotecan

2008
Sequential oral hydroxyurea and intravenous cytosine arabinoside in refractory childhood acute leukemia: a pediatric oncology group phase 1 study.
    Journal of pediatric hematology/oncology, 2008, Volume: 30, Issue:5

    Topics: Adolescent; Adult; Child; Child, Preschool; Cytarabine; Humans; Hydroxyurea; Infections; Leukemia; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Myeloid, Acute; Liver; Skin; Survival Analysis

2008
Acyclovir bioavailability in patients with acute myelogenous leukemia treated with daunorubicin and cytarabine.
    Journal of clinical pharmacology, 2008, Volume: 48, Issue:8

    Topics: Acyclovir; Adolescent; Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Biological Availability; Cross-Over Studies; Cytarabine; Daunorubicin; Drug Interactions; Female; Humans; Intestinal Absorption; Leukemia, Myeloid, Acute; Male; Middle Aged

2008
Acute myelogenous leukaemia: maintenance chemotherapy after early consolidation treatment does not prolong survival.
    Lancet (London, England), 1984, Feb-18, Volume: 1, Issue:8373

    Topics: Adolescent; Adult; Aged; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Child; Clinical Trials as Topic; Cytarabine; Evaluation Studies as Topic; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisone; Prognosis; Random Allocation; Thioguanine; Thrombocytopenia; Vincristine

1984
Treatment of acute nonlymphocytic leukemia in adults: response to 2,2-anhydro-1-B-D-arabinofuranosyl-5-fluorocytosine and thioguanine on the L-12 protocol.
    Cancer, 1981, Nov-15, Volume: 48, Issue:10

    Topics: Adolescent; Adult; Aged; Ancitabine; Antineoplastic Agents; Bacterial Vaccines; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Pseudomonas aeruginosa; Random Allocation; Thioguanine

1981
A randomized comparison of postremission therapy in acute myelogenous leukemia: a Southeastern Cancer Study Group trial.
    Blood, 1984, Volume: 63, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; BCG Vaccine; Clinical Trials as Topic; Combined Modality Therapy; Cytarabine; Daunorubicin; Deoxyguanosine; Female; Humans; Immunotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Random Allocation; Thioguanine; Thionucleosides; United States

1984
Cooperative randomized studies on the treatment of adult acute leukemia in Poland. A comparison of two remission induction regimes and two maintenance regimes for AML.
    Folia haematologica (Leipzig, Germany : 1928), 1984, Volume: 111, Issue:2

    Topics: Adult; Animals; Blood Transfusion; Cattle; Cytarabine; Doxorubicin; Granulocytes; Humans; Leukemia, Myeloid, Acute; Middle Aged; Platelet Transfusion; Poland; Prospective Studies; Random Allocation; Thioguanine; Thymus Gland; Tissue Extracts

1984
Evaluation of cyclocytidine in reinduction and maintenance therapy of children with acute nonlymphocytic leukemia previously treated with cytosine arabinoside: a report from Children's Cancer Study Group.
    Medical and pediatric oncology, 1984, Volume: 12, Issue:5

    Topics: Adolescent; Adult; Ancitabine; Child; Child, Preschool; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Delayed-Action Preparations; Female; Humans; Infant; Injections, Intraperitoneal; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Lomustine; Male; Podophyllotoxin

1984
[New agents in the treatment of leukemia and lymphoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1983, Volume: 10, Issue:4 Pt 2

    Topics: Aclarubicin; Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Clinical Trials as Topic; Cytarabine; Doxorubicin; Drug Evaluation; Humans; Infusions, Parenteral; Leukemia, Myeloid, Acute; Lymphoma; Middle Aged; Naphthacenes

1983
Treatment of acute myelocytic leukemia with low-dose cytosine arabinoside: results of a pilot study in four patients.
    Leukemia research, 1983, Volume: 7, Issue:3

    Topics: Adult; Aged; Bone Marrow; Clinical Trials as Topic; Cytarabine; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male

1983
Effective chemotherapy of acute myelocytic leukemia occurring after alkylating agent or radiation therapy for prior malignancy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1983, Volume: 1, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Leukemia, Radiation-Induced; Male; Middle Aged; Neoplasms; Prospective Studies; Risk

1983
Contributions of host- and disease-related attributes to the outcome of patients with acute myelogenous leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1984, Volume: 2, Issue:4

    Topics: Actuarial Analysis; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Clinical Trials as Topic; Colony-Forming Units Assay; Cyclophosphamide; Cytarabine; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Humans; Leukemia, Myeloid, Acute; Middle Aged; Prognosis; Thioguanine; Time Factors; Vincristine

1984
Mitoxantrone as a single agent and in combination chemotherapy in patients with refractory acute leukemia.
    Seminars in oncology, 1984, Volume: 11, Issue:3 Suppl 1

    Topics: Acute Disease; Adolescent; Adult; Aged; Anthraquinones; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Clinical Trials as Topic; Cytarabine; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Prednisone; Vincristine

1984
Failure of lithium to limit neutropenia significantly during induction therapy of acute myelogenous leukemia. A Southeastern Cancer Study Group study.
    American journal of clinical oncology, 1984, Volume: 7, Issue:4

    Topics: Age Factors; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Evaluation; Female; Fever; Humans; Infections; Leukemia, Myeloid, Acute; Lithium; Lithium Carbonate; Male; Middle Aged; Neutropenia; Random Allocation; Thrombocytopenia

1984
Clinical value of empirical amphotericin B in patients with acute myelogenous leukemia.
    Cancer, 1982, Dec-01, Volume: 50, Issue:11

    Topics: Adult; Aged; Amphotericin B; Anti-Bacterial Agents; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mycoses; Pneumonia

1982
[Clinical activity of m-Amsa and the combination of m-Amsa with cytosine arabinoside].
    La Nouvelle presse medicale, 1982, Oct-09, Volume: 11, Issue:39

    Topics: Adolescent; Adult; Aminoacridines; Amsacrine; Antineoplastic Agents; Child; Clinical Trials as Topic; Cytarabine; Drug Synergism; Drug Therapy, Combination; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute

1982
Immunotherapy for remission maintenance in acute myeloblastic leukemia.
    Cancer immunology, immunotherapy : CII, 1982, Volume: 13, Issue:2

    Topics: Adult; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Follow-Up Studies; Humans; Immunotherapy; Leukemia, Myeloid, Acute; Mycobacterium bovis

1982
Short-term treatment for acute myelogenous leukaemia.
    British medical journal (Clinical research ed.), 1982, Apr-24, Volume: 284, Issue:6324

    Topics: Adolescent; Adult; Aged; Cytarabine; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Thioguanine

1982
Remission maintenance for acute nonlymphocytic leukemia: cytosine arabinoside plus 6-thioguanine versus a sequence of drug regimens.
    Cancer, 1980, Jul-01, Volume: 46, Issue:1

    Topics: Adolescent; Adult; BCG Vaccine; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Thioguanine; Time Factors

1980
Intensive chemotherapy for acute myelogenous leukemia.
    Annals of internal medicine, 1981, Volume: 94, Issue:6

    Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents; Child; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Sex Factors; Thioguanine

1981
Treatment of acute myelocytic leukemia: a study by cancer and leukemia group B.
    Blood, 1981, Volume: 58, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Random Allocation; Time Factors

1981
Adjuvant specific immunotherapy in maintenance treatment of adult acute non-lymphocytic leukemia.
    Klinische Wochenschrift, 1981, Nov-02, Volume: 59, Issue:21

    Topics: Adolescent; Adult; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Immunotherapy; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Thioguanine; Vincristine

1981
Cytosine arabinoside with daunorubicin or adriamycin for therapy of acute myelocytic leukemia: a CALGB study.
    Blood, 1982, Volume: 60, Issue:2

    Topics: Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Colitis, Ulcerative; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Middle Aged; Stomatitis

1982
Two years' experience in the treatment of acute myeloid leukaemia using a three-drug regimen: daunorubicin, cytosine arabinoside and 6-thioguanine.
    Irish medical journal, 1982, Volume: 75, Issue:11

    Topics: Adult; Aged; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Thioguanine

1982
Chemotherapy of the myeloid leukaemias.
    Journal of the Royal College of Physicians of London, 1980, Volume: 14, Issue:1

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Busulfan; Child; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Preleukemia; Remission, Spontaneous; Thioguanine

1980
Androgen therapy during myeloblastic leukemia remission induced by two drug combinations.
    Medicina, 1981, Volume: 41, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Agents; Child; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Middle Aged; Prednisone; Stanozolol; Vincristine

1981
[Results of a clinical study of the preparation Lenvis in leukemias in children and adults].
    Problemy gematologii i perelivaniia krovi, 1981, Volume: 26, Issue:12

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Clinical Trials as Topic; Cytarabine; Drug Therapy, Combination; Humans; Infant; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Middle Aged; Prednisolone; Thioguanine

1981
Maintenance chemoimmunotherapy of nonlymphoblastic acute leukemias.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1982, Volume: 80

    Topics: Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Clinical Trials as Topic; Cytarabine; Daunorubicin; Female; Humans; Immunotherapy; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukocyte Count; Leukocytes; Male; Middle Aged; Mycobacterium bovis; Thioguanine

1982
Treatment of acute myelogenous leukemia: influence of three induction regimens and maintenance with chemotherapy or BCG immunotherapy.
    Cancer, 1982, Apr-15, Volume: 49, Issue:8

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; BCG Vaccine; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Probability; Random Allocation; Thioguanine; Vincristine

1982
Progress in acute myelogenous leukemia.
    Cancer treatment reports, 1981, Volume: 65 Suppl 4

    Topics: Bone Marrow Transplantation; Clinical Trials as Topic; Cytarabine; Daunorubicin; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Graft vs Host Reaction; Humans; Immunotherapy; Leukemia, Myeloid, Acute; Middle Aged; Thioguanine; Time Factors

1981
A pilot study of the biologic and therapeutic effects of granulocyte colony-stimulating factor (filgrastim) in patients with acute myelogenous leukemia.
    Leukemia, 1995, Volume: 9, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Hematopoiesis; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Pilot Projects; Prospective Studies; Recombinant Proteins

1995
Intensive chemotherapy for poor prognosis myelodysplasia (MDS) and secondary acute myeloid leukemia (sAML) following MDS of more than 6 months duration. A pilot study by the Leukemia Cooperative Group of the European Organisation for Research and Treatmen
    Leukemia, 1995, Volume: 9, Issue:11

    Topics: Adolescent; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Europe; Humans; Idarubicin; Length of Stay; Leukemia, Myeloid, Acute; Middle Aged; Myelodysplastic Syndromes; Neoplasms, Second Primary; Pilot Projects; Prognosis; Prospective Studies; Survival Analysis

1995
High-dose cytosine arabinoside and daunorubicin postremission therapy in adults with de novo acute myeloid leukemia. Long-term follow-up of a prospective multicenter trial.
    Annals of hematology, 1995, Volume: 71, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Prospective Studies; Remission Induction; Survival Rate

1995
Treatment of myelodysplastic syndromes with AML-type chemotherapy.
    Leukemia & lymphoma, 1993, Volume: 11 Suppl 2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Karyotyping; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Prognosis; Remission Induction; Vidarabine

1993
Use of granulocyte colony-stimulating factor before, during, and after fludarabine plus cytarabine induction therapy of newly diagnosed acute myelogenous leukemia or myelodysplastic syndromes: comparison with fludarabine plus cytarabine without granulocyt
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1994, Volume: 12, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Cytarabine; Drug Administration Schedule; Female; Granulocyte Colony-Stimulating Factor; Humans; Incidence; Infections; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Neutrophils; Regression Analysis; Remission Induction; Survival Analysis; Treatment Outcome; Vidarabine

1994
Concurrent use of granulocyte colony-stimulating factor with low-dose cytosine arabinoside and aclarubicin for previously treated acute myelogenous leukemia: a pilot study.
    Leukemia, 1995, Volume: 9, Issue:1

    Topics: Aclarubicin; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Pilot Projects

1995
[Comparison of low-dose cytosine arabinoside and aclarubicin in combination with granulocyte colony-stimulating factor to intermediate-dose cytosine arabinoside and mitoxantrone with or without etoposide in the treatment of relapsed acute myeloid leukemia
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1995, Volume: 36, Issue:3

    Topics: Aclarubicin; Adolescent; Adult; Aged; Cytarabine; Drug Administration Schedule; Drug Therapy, Combination; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Recurrence

1995
Long-term follow-up of a randomized post-induction therapy trial in acute myelogenous leukemia (a Southeastern Cancer Study Group trial).
    Leukemia, 1995, Volume: 9, Issue:9

    Topics: Adolescent; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Patient Selection; Remission Induction; Thioguanine

1995
[Trial of combined cytosine arabinoside with granulocyte colony-stimulating factor therapy or refractory acute myeloid leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1995, Volume: 36, Issue:7

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

1995
[Continuous infusion therapy with low dose cytosine arabinoside and etoposide in acute myelogenous leukemia patients hardly tolerable for intensive combination chemotherapy].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1995, Volume: 36, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Etoposide; Female; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged

1995
Design and conduct of a double-blind, placebo-controlled trial of daunorubicin and cytarabine with or without granulocyte colony-stimulating factor in elderly patients with acute myeloid leukemia: a Southwest Oncology Group study.
    Journal of the National Cancer Institute. Monographs, 1995, Issue:19

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Double-Blind Method; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Randomized Controlled Trials as Topic; Recombinant Proteins

1995
Double-blind, placebo-controlled trial of daunorubicin and cytarabine with or without recombinant human granulocyte colony-stimulating factor in elderly patients with acute myeloid leukemia: economic evaluation with attention to inpatient and outpatient r
    Journal of the National Cancer Institute. Monographs, 1995, Issue:19

    Topics: Aged; Antineoplastic Agents; Cost-Benefit Analysis; Cytarabine; Daunorubicin; Double-Blind Method; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Middle Aged; Outpatients; Randomized Controlled Trials as Topic; Recombinant Proteins

1995
Pharmacokinetics of Ara-CMP-Stearate (YNK01): phase I study of the oral Ara-C derivative.
    Leukemia, 1995, Volume: 9, Issue:6

    Topics: Administration, Oral; Antineoplastic Agents; Arabinofuranosyluracil; Arabinonucleotides; Cytarabine; Cytidine Monophosphate; Dose-Response Relationship, Drug; Half-Life; Humans; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Statistics, Nonparametric

1995
Mitoxantrone, etoposide and ara-C vs doxorubicin-DNA, ara-C, thioguanine, vincristine and prednisolone in the treatment of patients with acute myelocytic leukaemia. A randomized comparison.
    European journal of haematology, 1995, Volume: 55, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; DNA Adducts; Doxorubicin; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Prednisolone; Recurrence; Survival Analysis; Thioguanine; Vincristine

1995
Fractionated total-body irradiation preceding high-dose cytosine arabinoside as a preparative regimen for bone marrow transplantation in children with acute leukemia.
    Medical and pediatric oncology, 1995, Volume: 25, Issue:3

    Topics: Adolescent; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Humans; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Survival Analysis; Whole-Body Irradiation

1995
In vitro drug sensitivity of leukemic progenitors and P-glycoprotein expression in adult acute myeloid leukemia: correlation with induction treatment outcome.
    European journal of haematology, 1995, Volume: 55, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; ATP Binding Cassette Transporter, Subfamily B, Member 1; Colony-Forming Units Assay; Cytarabine; Daunorubicin; Drug Screening Assays, Antitumor; Humans; Leukemia, Myeloid, Acute; Middle Aged; Neoplastic Stem Cells; Remission Induction

1995
All-trans retinoic acid and low-dose cytosine arabinoside for the treatment of 'poor prognosis' acute myeloid leukemia.
    Leukemia, 1995, Volume: 9, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Remission Induction; Tretinoin

1995
Aggressive chemotherapy combined with G-CSF and maintenance therapy with interleukin-2 for patients with advanced myelodysplastic syndrome, subacute or secondary acute myeloid leukemia--initial results.
    Annals of hematology, 1993, Volume: 66, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Interleukin-2; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Remission Induction

1993
Treatment of acute myelogenous leukemia in patients over 50 years of age with V-TAD: a Southwest Oncology Group study.
    American journal of hematology, 1995, Volume: 48, Issue:4

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Survival Analysis; Thioguanine; United States

1995
Granulocyte-macrophage colony stimulating factor (GM-CSF) priming in the treatment of elderly patients with acute myelogenous leukemia.
    American journal of hematology, 1995, Volume: 49, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bone Marrow; Cell Cycle; Cytarabine; Disease-Free Survival; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Survival Rate

1995
Granulocyte-macrophage colony-stimulating factor after initial chemotherapy for elderly patients with primary acute myelogenous leukemia. Cancer and Leukemia Group B.
    The New England journal of medicine, 1995, Jun-22, Volume: 332, Issue:25

    Topics: Aged; Aged, 80 and over; Cytarabine; Daunorubicin; Double-Blind Method; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunosuppression Therapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Regression Analysis; Remission Induction; Treatment Outcome

1995
[Treatment results of acute nonlymphocytic leukemia in childhood--Kyushu Yamaguchi Children's Cancer Study Group].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1995, Volume: 36, Issue:4

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Prednisolone; Recurrence; Remission Induction; Survival Rate; Vincristine

1995
Autologous or allogeneic bone marrow transplantation compared with intensive chemotherapy in acute myelogenous leukemia. European Organization for Research and Treatment of Cancer (EORTC) and the Gruppo Italiano Malattie Ematologiche Maligne dell'Adulto (
    The New England journal of medicine, 1995, Jan-26, Volume: 332, Issue:4

    Topics: Adolescent; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Prospective Studies; Remission Induction; Transplantation, Autologous; Transplantation, Homologous

1995
The influence of induction chemotherapy dose and dose intensity on the duration of remission in acute myeloid leukemia. Australian Leukemia Study Group.
    Leukemia & lymphoma, 1994, Volume: 15, Issue:1-2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Australia; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Etoposide; Humans; Leukemia, Myeloid, Acute; Life Tables; Prognosis; Proportional Hazards Models; Remission Induction; Survival Analysis; Treatment Outcome

1994
[High-dose cytarabine as intensive postremission therapy in acute myelogenous leukemia: effect on long-term disease-free survival].
    Zhonghua nei ke za zhi, 1994, Volume: 33, Issue:7

    Topics: Adolescent; Adult; Aged; Child; Cytarabine; Disease-Free Survival; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction

1994
Improved survival for patients with acute myelogenous leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1995, Volume: 13, Issue:3

    Topics: Adolescent; Adult; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Prospective Studies; Regression Analysis; Remission Induction; Survival Rate; Transplantation, Autologous; Transplantation, Homologous; United States

1995
Relation between platinum-DNA adducts and complete remission in adult acute nonlymphocytic leukemia.
    Leukemia research, 1994, Volume: 18, Issue:9

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cisplatin; Cytarabine; DNA Adducts; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Organoplatinum Compounds; Predictive Value of Tests; Recurrence; Remission Induction

1994
Recombinant human granulocyte-macrophage colony-stimulating factor in combination with standard induction chemotherapy in acute myeloid leukemia evolving from myelodysplastic syndromes: a pilot study.
    Leukemia, 1994, Volume: 8, Issue:10

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Myelodysplastic Syndromes; Pilot Projects; Prognosis; Recombinant Proteins; Remission Induction; Thioguanine

1994
Cytosine arabinoside and mitoxantrone induction chemotherapy followed by bone marrow transplantation or chemotherapy for relapsed or refractory pediatric acute myeloid leukemia.
    Leukemia, 1994, Volume: 8, Issue:10

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Disease-Free Survival; Female; Follow-Up Studies; Humans; Infant; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Recurrence; Remission Induction; Salvage Therapy

1994
A phase III trial of high-dose cytosine arabinoside with or without etoposide in relapsed and refractory acute myelogenous leukemia. A Southeastern Cancer Study Group trial.
    Leukemia, 1994, Volume: 8, Issue:11

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Humans; Leukemia, Myeloid, Acute; Survival Analysis

1994
[Role of double induction in the treatment of acute myeloblastic leukemia in the adult: intermediate results of protocol LAM90].
    Nouvelle revue francaise d'hematologie, 1994, Volume: 36 Suppl 2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Cytarabine; Etoposide; Humans; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Remission Induction

1994
[Results of induction treatment with idarubicin for acute nonlymphoblastic leukemia in adults].
    Acta haematologica Polonica, 1994, Volume: 25, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Prospective Studies; Treatment Outcome

1994
Salvage therapy with low-dose cytosine arabinoside in refractory or relapsed acute non-lymphocytic leukaemia: a report on 25 patients.
    European journal of haematology, 1994, Volume: 52, Issue:4

    Topics: Adolescent; Adult; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

1994
Results of conventional-dose cytosine arabinoside and idarubicin in elderly patients with acute myeloid leukemia.
    Annals of hematology, 1994, Volume: 68, Issue:6

    Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Humans; Idarubicin; Leukemia, Erythroblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Middle Aged; Survival Analysis

1994
Long-term results following treatment of newly-diagnosed acute myelogenous leukemia with continuous-infusion high-dose cytosine arabinoside.
    Leukemia, 1994, Volume: 8, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Chromosome Inversion; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 17; Cytarabine; Cytogenetics; Dose-Response Relationship, Drug; Doxorubicin; Follow-Up Studies; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Middle Aged; Prognosis; Recurrence; Survival Analysis; Time Factors; Translocation, Genetic

1994
A randomized study of mitoxantrone plus cytarabine versus daunomycin plus cytarabine in the treatment of previously untreated adult patients with acute nonlymphocytic leukemia.
    Annals of hematology, 1994, Volume: 69, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Time Factors

1994
Phase II-trial of double-consolidation following intensive induction treatment for improvement of survival in elderly patients with acute myeloid leukemia.
    Leukemia & lymphoma, 1994, Volume: 12, Issue:5-6

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Survival Rate

1994
Effects of bone marrow transplantation on myocardial function in children.
    Bone marrow transplantation, 1994, Volume: 13, Issue:2

    Topics: Adolescent; Adult; Blood Pressure; Bone Marrow Transplantation; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dose-Response Relationship, Drug; Echocardiography; Female; Heart; Humans; Infant; Leukemia, Myeloid, Acute; Male; Melphalan; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radionuclide Angiography; Time Factors; Transplantation, Autologous; Transplantation, Homologous; Whole-Body Irradiation

1994
[A late phase II comparative study of idarubicin + cytarabine and daunorubicin + cytarabine in adult patients with acute non-lymphocytic leukemia. Idarubicin Study Group].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:13

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Electrocardiography; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction

1993
Effect of induction cytarabine dose intensity on long-term survival in acute myelogenous leukemia: results of a randomized, controlled study.
    Leukemia & lymphoma, 1993, Volume: 11, Issue:1-2

    Topics: Adolescent; Adult; Aged; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Survival Rate

1993
Phase I study of a continuous infusion of high-dose ara-C in conjunction with a fixed dose of 2'-deoxycytidine (IND 28108) in patients with refractory leukemia: an interim report.
    Leukemia, 1993, Volume: 7, Issue:12

    Topics: Adult; Aged; Blast Crisis; Cytarabine; Deoxycytidine; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Middle Aged; Neutropenia; Remission Induction; Thrombocytopenia

1993
Efficacy of etoposide and mitoxantrone in patients with acute myelogenous leukemia refractory to standard induction therapy and intermediate-dose cytarabine with amsidine. Dutch Hematology-Oncology Working Group for Adults (HOVON).
    Leukemia, 1994, Volume: 8, Issue:1

    Topics: Adolescent; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Remission Induction

1994
Idarubicin plus continuous-infusion high-dose cytarabine as treatment for patients with acute myelogenous leukemia or myelodysplastic syndrome.
    Seminars in oncology, 1993, Volume: 20, Issue:6 Suppl 8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Humans; Idarubicin; Leukemia, Myeloid, Acute; Middle Aged; Myelodysplastic Syndromes; Remission Induction; Survival Rate

1993
Results of treatment with an intensive combination induction regimen containing idarubicin in children with acute myeloblastic leukemia: preliminary report of the Argentine Group for Treatment of Acute Leukemia.
    Seminars in oncology, 1993, Volume: 20, Issue:6 Suppl 8

    Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Drug Administration Schedule; Etoposide; Female; Humans; Idarubicin; Infant; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Remission Induction; Survival Analysis

1993
[Refractory acute myelogenous leukemia successfully treated with a continuous infusion chemotherapy of low dose aclarubicin and cytosine arabinoside: a case report].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1993, Volume: 34, Issue:5

    Topics: Aclarubicin; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute

1993
Fludarabine and arabinosylcytosine therapy of refractory and relapsed acute myelogenous leukemia.
    Leukemia & lymphoma, 1993, Volume: 9, Issue:4-5

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Bone Marrow Transplantation; Colitis; Combined Modality Therapy; Conjunctivitis; Cytarabine; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Pancreatitis; Peripheral Nervous System Diseases; Remission Induction; Salvage Therapy; Treatment Outcome; Vidarabine

1993
Chemotherapy with high-dose cytosine arabinoside and mitoxantrone for poor-prognosis myeloid leukemias.
    Cancer investigation, 1993, Volume: 11, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Prognosis; Prospective Studies; Treatment Outcome

1993
Phase I clinical and pharmacokinetic evaluation of high-dose mitoxantrone in combination with cytarabine in patients with acute leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1993, Volume: 11, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Chemical and Drug Induced Liver Injury; Cytarabine; Drug Administration Schedule; Female; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Accelerated Phase; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma

1993
Mitoxantrone and cytosine arabinoside as treatment for acute myelogenous leukemia (AML) at first recurrence.
    Leukemia, 1993, Volume: 7, Issue:10

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Remission Induction; Time Factors

1993
Granulocyte-macrophage colony-stimulating factor in association to timed-sequential chemotherapy with mitoxantrone, etoposide, and cytarabine for refractory acute myelogenous leukemia.
    Leukemia, 1993, Volume: 7, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Cytarabine; Drug Administration Schedule; Etoposide; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Pilot Projects; Recombinant Proteins

1993
Phase-II study of treatment of refractory acute leukemia with intermediate-dose cytosine arabinoside and amsacrine.
    Annals of hematology, 1993, Volume: 66, Issue:3

    Topics: Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Resistance; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction

1993
High-dose versus intermediate dose cytosine arabinoside combined with mitoxantrone for the treatment of relapsed and refractory acute myeloid leukemia: results of an age adjusted randomized comparison.
    Leukemia & lymphoma, 1993, Volume: 10 Suppl

    Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Prospective Studies; Recurrence

1993
[Early phase II study of Idarubicin combined with cytarabine in acute myelogenous leukemia. Idarubicin Study Group].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:7

    Topics: Adult; Aged; Alopecia; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Female; Humans; Idarubicin; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged

1993
Prospective comparative study of bone marrow transplantation and postremission chemotherapy for childhood acute myelogenous leukemia. The Associazione Italiana Ematologia ed Oncologia Pediatrica Cooperative Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1993, Volume: 11, Issue:6

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Daunorubicin; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Prospective Studies; Remission Induction; Survival Rate; Thioguanine

1993
[Comparison between intensive consolidation by bone marrow autograft or by chemotherapy of acute myeloblastic leukemias in 1st complete remission: AML8A protocol of the Leukemia Cooperative Group of the European Organization for Research and Treatment of
    Nouvelle revue francaise d'hematologie, 1993, Volume: 35, Issue:1

    Topics: Actuarial Analysis; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Remission Induction; Survival Analysis; Transplantation, Autologous

1993
Chlorodeoxyadenosine and arabinosylcytosine in patients with acute myelogenous leukemia: pharmacokinetic, pharmacodynamic, and molecular interactions.
    Blood, 1996, Jan-01, Volume: 87, Issue:1

    Topics: Adenosine Triphosphate; Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Base Sequence; Biotransformation; Cladribine; Cytarabine; DNA Replication; DNA, Neoplasm; Humans; Leukemia, Myeloid, Acute; Molecular Sequence Data; Neoplasm Proteins; Neoplastic Stem Cells; Prodrugs; Ribonucleotide Reductases; Salvage Therapy

1996
Granulocyte colony-stimulating factor following chemotherapy in elderly patients with newly diagnosed acute myelogenous leukemia.
    Leukemia, 1996, Volume: 10, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Neutropenia; Pilot Projects; Remission Induction; Survival Rate

1996
Recombinant human interleukin-3 (rH IL-3) in combination with remission induction chemotherapy in patients with relapsed acute myelogenous leukemia (AML): a phase I/II study.
    Leukemia, 1996, Volume: 10, Issue:1

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Daunorubicin; Female; Humans; Interleukin-3; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Mitoxantrone; Platelet Count; Recombinant Proteins; Recurrence; Remission Induction

1996
MEC (mitoxantrone, etoposide and intermediate dose cytarabine): an effective induction regimen for previously untreated acute non-lymphocytic leukemia.
    Leukemia & lymphoma, 1995, Volume: 19, Issue:5-6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Life Tables; Male; Middle Aged; Mitoxantrone; Remission Induction; Salvage Therapy; Survival Rate

1995
Post-remission intensive consolidation with high-dose cytarabine-based chemotherapy and granulocyte colony-stimulatory factor in adults with acute myelogenous leukemia: a preliminary report.
    Zhonghua yi xue za zhi = Chinese medical journal; Free China ed, 1995, Volume: 56, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Neutropenia; Remission Induction

1995
A prospective randomized trial of idarubicin vs daunorubicin in combination chemotherapy for acute myelogenous leukemia of the age group 55 to 75.
    Leukemia, 1996, Volume: 10, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chi-Square Distribution; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Prospective Studies; Regression Analysis; Remission Induction; Survival Rate

1996
Autologous bone marrow transplantation in late first complete remission improves outcome in acute myelogenous leukemia.
    Leukemia, 1996, Volume: 10, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Follow-Up Studies; Humans; Idarubicin; Leukemia, Myeloid, Acute; Logistic Models; Male; Middle Aged; Prognosis; Proportional Hazards Models; Remission Induction; Survival Rate; Time Factors; Transplantation, Autologous

1996
Granulocyte-macrophage colony-stimulating factor associated with induction treatment of acute myelogenous leukemia: a randomized trial by the European Organization for Research and Treatment of Cancer Leukemia Cooperative Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1996, Volume: 14, Issue:7

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged; Neutropenia; Survival Rate

1996
[Intensive post-remission therapy in acute myeloid leukemia. Results of a prospective comparative study by the South Germany Hemoblastosis Group].
    Medizinische Klinik (Munich, Germany : 1983), 1996, Apr-12, Volume: 91 Suppl 3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Etoposide; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prospective Studies; Remission Induction; Survival Rate; Treatment Outcome

1996
In vivo purging with high-dose cytarabine followed by high-dose chemoradiotherapy and reinfusion of unpurged bone marrow for adult acute myelogenous leukemia in first complete remission.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1996, Volume: 14, Issue:8

    Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Purging; Bone Marrow Transplantation; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Disease-Free Survival; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prospective Studies; Recurrence; Regression Analysis; Remission Induction; Transplantation, Autologous; Whole-Body Irradiation

1996
Salvage treatment for primary resistant acute myelogenous leukemia consisting of intermediate-dose cytosine arabinoside and interspaced continuous infusions of idarubicin: a phase-II study (no. 06901) of the EORTC Leukemia Cooperative Group.
    Annals of hematology, 1996, Volume: 72, Issue:3

    Topics: Adolescent; Adult; Bone Marrow Transplantation; Cytarabine; Drug Administration Schedule; Drug Resistance, Neoplasm; Humans; Idarubicin; Leukemia, Myeloid, Acute; Middle Aged; Remission Induction; Salvage Therapy; Survival Analysis; Treatment Outcome

1996
Heterogeneous effects of G-CSF and GM-CSF on cell growth and ara-C cytotoxicity in childhood leukemias which express myeloid markers.
    Leukemia & lymphoma, 1996, Volume: 22, Issue:3-4

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Cell Division; Child; Child, Preschool; Cytarabine; Drug Synergism; Female; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunophenotyping; Infant; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemia, Promyelocytic, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Thymidine; Tritium

1996
[Low-dose cytosine arabinoside and aclarubicin in combination with granulocyte colony-stimulating factor for the treatment of relapsed acute myeloid leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1996, Volume: 37, Issue:8

    Topics: Aclarubicin; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Quality of Life; Recurrence; Remission Induction; Survival Rate

1996
Clinical and laboratory studies of 2-chlorodeoxyadenosine +/- cytosine arabinoside for relapsed or refractory acute myelogenous leukemia in adults.
    Leukemia, 1996, Volume: 10, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Cladribine; Cytarabine; Humans; Leukemia, Myeloid, Acute; Middle Aged; Recurrence

1996
BAVC regimen and autograft for acute myelogenous leukemia in second complete remission.
    Bone marrow transplantation, 1996, Volume: 18, Issue:4

    Topics: Adolescent; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmustine; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Etoposide; Female; Follow-Up Studies; Humans; Infant; Leukemia, Myeloid, Acute; Male; Middle Aged; Time Factors; Transplantation Conditioning; Transplantation, Autologous

1996
[Treatment results for unselected patients with acute myelogenous leukemia. During a 10-year period, August 1984 to July 1994].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1996, Volume: 37, Issue:9

    Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Mitoxantrone; Patient Selection; Prednisolone; Remission Induction; Retrospective Studies; Treatment Outcome

1996
A phase II comparative study of idarubicin plus cytarabine versus daunorubicin plus cytarabine in adult acute myeloid leukemia.
    Seminars in hematology, 1996, Volume: 33, Issue:4 Suppl 3

    Topics: Adolescent; Adult; Age Distribution; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Data Interpretation, Statistical; Daunorubicin; Electrocardiography; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction

1996
Induction therapy of newly diagnosed acute nonlymphocytic leukemia with idarubicin and cytosine arabinoside--the Taiwan experience.
    Seminars in hematology, 1996, Volume: 33, Issue:4 Suppl 3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chi-Square Distribution; Cytarabine; Disease-Free Survival; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Taiwan

1996
Induction chemotherapy with idarubicin plus N4-behenoyl-1-beta-D-arabinofuranosylcytosine in acute myelogenous leukemia: a newly designed induction regimen--a prospective, cooperative multicenter study.
    Seminars in hematology, 1996, Volume: 33, Issue:4 Suppl 3

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Female; Humans; Idarubicin; Infant; Leukemia, Myeloid, Acute; Male; Middle Aged; Prospective Studies; Remission Induction

1996
Intensive chemotherapy with idarubicin, cytosine arabinoside, and granulocyte colony-stimulating factor (G-CSF) in patients with secondary and therapy-related acute myelogenous leukemia. Club de Réflexion en Hématologie.
    Leukemia, 1997, Volume: 11, Issue:1

    Topics: Adult; Aged; Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Examination; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Feasibility Studies; Female; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasms, Second Primary; Prospective Studies; Remission Induction

1997
Probability of long-term disease-free survival for acute myeloid leukemia patients after first relapse: A single-centre experience.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1996, Volume: 7, Issue:9

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Etoposide; Female; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Male; Middle Aged; Mitoxantrone; Survival Analysis; Treatment Outcome

1996
[Myelogenous leukemia in children. ANLL9205 study by Children's Cancer and Leukemia Study Group (CCLSG)].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1997, Volume: 38, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Prognosis; Remission Induction; Risk Factors; Vincristine

1997
[Short-term intensive treatment for acute myelogenous leukemia (excluding M3 subtype) in adults].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1997, Volume: 38, Issue:3

    Topics: Aclarubicin; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Middle Aged; Mitoxantrone; Time Factors; Vinblastine; Vincristine

1997
Intensive chemotherapy of poor prognosis myelodysplastic syndromes (MDS) and acute myeloid leukemia following MDS with idarubicin and cytarabine.
    Leukemia research, 1997, Volume: 21, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Humans; Idarubicin; Infusions, Intravenous; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Middle Aged; Myelodysplastic Syndromes; Pilot Projects; Prognosis; Prospective Studies

1997
Acute myeloid leukemia in the elderly: assessment of multidrug resistance (MDR1) and cytogenetics distinguishes biologic subgroups with remarkably distinct responses to standard chemotherapy. A Southwest Oncology Group study.
    Blood, 1997, May-01, Volume: 89, Issue:9

    Topics: Age Factors; Aged; Aged, 80 and over; Antigens, CD; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Daunorubicin; Double-Blind Method; Drug Resistance, Multiple; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Neoplasms, Second Primary; Recombinant Proteins

1997
Long-term outcome of high-dose cytarabine-based consolidation chemotherapy for older patients with acute myelogenous leukemia.
    Leukemia & lymphoma, 1997, Volume: 25, Issue:1-2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Preleukemia; Prognosis; Risk Factors; Treatment Outcome

1997
Comparison of efficacies of ondansetron and dixyrazine for prophylaxis of emesis during induction treatment in acute myelogenous leukemia. A pilot study.
    Acta oncologica (Stockholm, Sweden), 1997, Volume: 36, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Amsacrine; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Ondansetron; Phenothiazines; Pilot Projects; Serotonin Antagonists; Vomiting

1997
Idarubicin and intermediate dose ARA-C followed by consolidation chemotherapy or bone marrow transplantation in relapsed or refractory acute myeloid leukemia.
    Leukemia & lymphoma, 1997, Volume: 25, Issue:3-4

    Topics: Acute Disease; Adult; Agranulocytosis; Antibiotics, Antineoplastic; Bone Marrow Transplantation; Cytarabine; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Humans; Idarubicin; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Nausea; Remission Induction; Thrombocytopenia; Treatment Outcome; Vomiting

1997
[Treatment results in childhood acute myeloblastic leukemia--a report of clinical trials of a past decade from the Japanese children's Cancer and Leukemia Study Group (CCLSG)].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1997, Volume: 38, Issue:6

    Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Humans; Leukemia, Myeloid, Acute; Remission Induction; Tretinoin

1997
Phase I/II study of idarubicin given with continuous infusion fludarabine followed by continuous infusion cytarabine in children with acute leukemia: a report from the Children's Cancer Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:8

    Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Female; Humans; Idarubicin; Infant; Infusions, Intravenous; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Vidarabine

1997
Transplantation of autologous peripheral blood progenitor cells procured after high-dose cytarabine-based consolidation chemotherapy for adults with acute myelogenous leukemia in first remission.
    Leukemia, 1997, Volume: 11, Issue:9

    Topics: Adult; Combined Modality Therapy; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Recombinant Proteins; Survival Analysis; Transplantation, Autologous

1997
Induction failure in de novo acute myelogenous leukemia is associated with expression of high levels of CD34 antigen by the leukemic blasts.
    Leukemia & lymphoma, 1997, Volume: 26, Issue:3-4

    Topics: Adult; Aged; Aged, 80 and over; Antigens, CD34; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Remission Induction

1997
Sequential mitoxantrone, daunorubicin, and cytosine arabinoside for patients with newly diagnosed acute myelocytic leukemia.
    American journal of hematology, 1997, Volume: 56, Issue:4

    Topics: Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Pilot Projects

1997
Pharmacokinetic and pharmacodynamic studies of fludarabine and cytosine arabinoside administered as loading boluses followed by continuous infusions after a phase I/II study in pediatric patients with relapsed leukemias. The Children's Cancer Group.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Child; Child, Preschool; Cytarabine; Humans; Infant; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Vidarabine

1998
CECA-cyclophosphamide, etoposide, carboplatin and cytosine arabinoside--a new salvage regimen for relapsed or refractory acute myelogenous leukemia.
    Leukemia & lymphoma, 1998, Volume: 28, Issue:3-4

    Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Cytarabine; Doxorubicin; Humans; Leukemia, Myeloid, Acute; Podophyllotoxin; Recurrence; Remission Induction; Salvage Therapy

1998
Treatment of acute myelogenous leukemia in the older patient with attenuated high-dose ara-C.
    American journal of clinical oncology, 1998, Volume: 21, Issue:2

    Topics: Aged; Antimetabolites, Antineoplastic; Cytarabine; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Remission Induction; Survival Analysis

1998
Autologous peripheral blood progenitor cell transplantation mobilized with high-dose cytarabine in acute myeloid leukemia in first complete remission.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1998, Volume: 9, Issue:2

    Topics: Adolescent; Adult; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Purging; Busulfan; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Disease-Free Survival; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Male; Middle Aged; Mitoxantrone; Remission Induction; Transplantation, Autologous

1998
Cytosine arabinoside, etoposide and aclarubicin (AVA) for the treatment of acute myeloid leukemia (AML) in elderly patients.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1998, Volume: 9, Issue:2

    Topics: Aclarubicin; Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Male

1998
[Treatment of children with non-Hodgkin's lymphoma with CCLSG NHL 855/890 protocols long-term outcome and incidence of secondary malignancies].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1998, Volume: 39, Issue:4

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Hydrocortisone; Infant; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Mercaptopurine; Methotrexate; Neoplasms, Second Primary; Prednisolone; Remission Induction; Treatment Outcome; Vincristine

1998
Chemotherapy of acute myeloblastic leukaemia with DAM regimen.
    Bangladesh Medical Research Council bulletin, 1997, Volume: 23, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Cytarabine; Disease-Free Survival; Doxorubicin; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction

1997
[A pharmacokinetic study of the value of oral cytarabine ocfosfate in the treatment of hematological malignancies].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1998, Volume: 39, Issue:5

    Topics: Administration, Oral; Aged; Antineoplastic Agents; Arabinonucleotides; Cytarabine; Cytidine Monophosphate; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Time Factors

1998
Comparison between four and eight cycles of intensive chemotherapy in adult acute myeloid leukemia: a randomized trial of the Finnish Leukemia Group.
    Leukemia, 1998, Volume: 12, Issue:7

    Topics: Aclarubicin; Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Administration Schedule; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisolone; Prospective Studies; Remission Induction; Vincristine

1998
Adjuvant treatment with cyclosporin A increases the toxicity of chemotherapy for remission induction in acute non-lymphocytic leukemia.
    Leukemia, 1998, Volume: 12, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bilirubin; Chemotherapy, Adjuvant; Creatinine; Cyclosporine; Cytarabine; Feasibility Studies; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Treatment Outcome

1998
Tallimustine, an effective antileukemic agent in a severe combined immunodeficient mouse model of adult myelogenous leukemia, induces remissions in a phase I study.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1997, Volume: 3, Issue:12 Pt 1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Agents; Cytarabine; Diarrhea; Distamycins; Drug Administration Schedule; Female; Humans; Injections, Intravenous; Leukemia; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Mice; Mice, SCID; Middle Aged; Nausea; Nitrogen Mustard Compounds; Transplantation, Heterologous; Tumor Cells, Cultured; Vomiting

1997
Modulation of the cellular metabolism of cytarabine and fludarabine by granulocyte-colony-stimulating factor during therapy of acute myelogenous leukemia.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1995, Volume: 1, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biotransformation; Blast Crisis; Cell Cycle; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; In Vitro Techniques; Infusions, Intravenous; Kinetics; Leukemia, Myeloid, Acute; Pilot Projects; Vidarabine

1995
Randomised unicenter trial for comparison of three regimens in de novo adult acute nonlymphoblastic leukaemia.
    Medical oncology (Northwood, London, England), 1998, Volume: 15, Issue:3

    Topics: Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Remission Induction; Survival Analysis

1998
High single dose of mitoxantrone and cytarabine in acute non-lymphocytic leukemia: a pharmacokinetic and clinical study.
    Therapeutic drug monitoring, 1998, Volume: 20, Issue:6

    Topics: Adult; Aged; Amsacrine; Chromatography, High Pressure Liquid; Cytarabine; Drug Administration Schedule; Etoposide; Female; Humans; Injections, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Neutropenia; Time Factors

1998
[A phase II study with high-dose cytarabine (NS-075) in adult patients with relapsed and refractory acute leukemia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1998, Volume: 25, Issue:14

    Topics: Adolescent; Adult; Aged; Anorexia; Antimetabolites, Antineoplastic; Cytarabine; Diarrhea; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged; Nausea; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Vomiting

1998
[Pilot late phase II study of KRN8602 (MX2), a novel anthracycline derivative, for acute leukemia--a dose finding study in combination].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:1

    Topics: Adult; Aged; Anorexia; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carubicin; Cytarabine; Female; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged; Nausea; Pilot Projects; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction; Vincristine; Vomiting, Anticipatory

1999
Priming with G-CSF effectively enhances low-dose Ara-C-induced in vivo apoptosis in myeloid leukemia cells.
    Experimental hematology, 1999, Volume: 27, Issue:2

    Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Apoptosis; Cytarabine; Drug Synergism; Drug Therapy, Combination; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

1999
FLAG (fludarabine, high-dose cytarabine, and G-CSF) for refractory and high-risk relapsed acute leukemia in children.
    Medical and pediatric oncology, 1999, Volume: 32, Issue:6

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Infant; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Treatment Outcome; Vidarabine

1999
Double induction strategy for acute myeloid leukemia: the effect of high-dose cytarabine with mitoxantrone instead of standard-dose cytarabine with daunorubicin and 6-thioguanine: a randomized trial by the German AML Cooperative Group.
    Blood, 1999, Jun-15, Volume: 93, Issue:12

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cytarabine; Daunorubicin; Humans; Karyotyping; L-Lactate Dehydrogenase; Leukemia, Myeloid, Acute; Leukocyte Count; Middle Aged; Mitoxantrone; Prognosis; Remission Induction; Thioguanine; Treatment Outcome

1999
GM-CSF, ARA-C, VP-16 and idarubicin (GM-IVA), a short, and effective induction treatment for de novo AML, suitable for the elderly.
    Journal of experimental & clinical cancer research : CR, 1999, Volume: 18, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Cytarabine; Disease-Free Survival; Drug Administration Schedule; Female; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Idarubicin; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Prognosis; Survival Analysis; Vidarabine

1999
A prospective randomized trial of KRN8602 and cytosine arabinoside vs. daunorubicin and cytosine arabinoside in adult patients with newly diagnosed acute myelogenous leukemia. The KRN8602 Leukemia Study Group.
    International journal of hematology, 1999, Volume: 70, Issue:1

    Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carubicin; Central Nervous System Diseases; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prospective Studies; Treatment Outcome

1999
Comparison of leukopenia between cytarabine and behenoyl cytarabine in JALSG AML-89 consolidation therapy. The Japan Adult Leukemia Study Group.
    International journal of hematology, 1999, Volume: 70, Issue:1

    Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Leukopenia; Prospective Studies

1999
Quinine improves results of intensive chemotherapy (IC) in myelodysplastic syndromes (MDS) expressing P-glycoprotein (PGP). Updated results of a randomized study. Groupe Français des Myélodysplasies (GFM) and Groupe GOELAMS.
    Advances in experimental medicine and biology, 1999, Volume: 457

    Topics: Adult; Aged; Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Aberrations; Cytarabine; Disease Progression; Female; Genes, MDR; Humans; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Myelodysplastic Syndromes; Phenotype; Quinine; Remission Induction; Survival Analysis

1999
Treatment of poor prognosis AML patients using PSC833 (valspodar) plus mitoxantrone, etoposide, and cytarabine (PSC-MEC).
    Advances in experimental medicine and biology, 1999, Volume: 457

    Topics: Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporins; Cytarabine; Etoposide; Genes, MDR; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Prognosis; Remission Induction; Salvage Therapy

1999
Prognosis in adult AML is precisely predicted by the DISC-assay using the chemosensitivity-index Ci.
    Advances in experimental medicine and biology, 1999, Volume: 457

    Topics: Adult; Aminoglutethimide; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Cell Survival; Cytarabine; Danazol; Drug Screening Assays, Antitumor; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Predictive Value of Tests; Prognosis; Prospective Studies; Regression Analysis; Remission Induction; Survival Analysis; Tamoxifen; Vidarabine

1999
Patients with t(8;21)(q22;q22) and acute myeloid leukemia have superior failure-free and overall survival when repetitive cycles of high-dose cytarabine are administered.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1999, Volume: 17, Issue:12

    Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prospective Studies; Survival Analysis; Translocation, Genetic

1999
A phase I-II trial of escalating doses of mitoxantrone with fixed doses of cytarabine plus fludarabine as salvage therapy for patients with acute leukemia and the blastic phase of chronic myelogenous leukemia.
    Cancer, 1999, Dec-01, Volume: 86, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Cytarabine; DNA Damage; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Salvage Therapy; Treatment Outcome; Vidarabine

1999
Clinical and laboratory evaluation of all-trans retinoic acid modulation of chemotherapy in patients with acute myelogenous leukaemia.
    British journal of haematology, 2000, Volume: 108, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cytarabine; Female; Genes, bcl-2; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Proto-Oncogene Proteins c-bcl-2; Recurrence; Survival Analysis; Treatment Outcome; Tretinoin

2000
[A randomized trial of conventional dose vs reduced dose in BHAC-DM therapy for acute myelogenous leukemia in elderly patients].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2000, Volume: 41, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Prednisolone; Prognosis; Prospective Studies; Remission Induction; Vincristine

2000
An effective chemotherapeutic regimen for acute myeloid leukemia and myelodysplastic syndrome in children with Down's syndrome.
    Leukemia, 2000, Volume: 14, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Cytarabine; Daunorubicin; Disease-Free Survival; Down Syndrome; Etoposide; Female; Humans; Infant; Leukemia, Megakaryoblastic, Acute; Leukemia, Myeloid, Acute; Male; Myelodysplastic Syndromes; Probability; Remission Induction; Survival Rate; Time Factors; Treatment Outcome

2000
Treatment with low-dose cytosine arabinoside followed by administration of macrophage colony-stimulating factor prolongs the survival of patients with RAEB, RAEB-T, or leukemic phase myelodysplastic syndrome: a pilot study.
    International journal of hematology, 2000, Volume: 71, Issue:4

    Topics: Adult; Aged; Anemia, Refractory, with Excess of Blasts; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Macrophage Colony-Stimulating Factor; Male; Middle Aged; Myelodysplastic Syndromes; Pilot Projects; Survival Rate; Treatment Outcome

2000
Poor prognosis acute myelogenous leukemia: 1 - response to treatment with high dose cytarabine/mitoxantrone/ethyol @ (Amifostine).
    Leukemia research, 2000, Volume: 24, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Amifostine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Pilot Projects; Prognosis; Radiation-Protective Agents; Treatment Outcome

2000
[Effect of etoposide added to individualized induction therapy of adult acute myeloid leukemia--the JALSG-AML-92 Study. Japan Adult Leukemia Study Group].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:8

    Topics: Adolescent; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Administration Schedule; Etoposide; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Middle Aged; Prospective Studies

2000
High-dose treatment with autologous bone marrow support as consolidation of first remission in younger patients with acute myelogenous leukaemia.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2000, Volume: 11, Issue:8

    Topics: Adolescent; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Doxorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neutropenia; Prognosis; Survival Analysis; Thioguanine; Transplantation, Autologous; Treatment Outcome; Whole-Body Irradiation

2000
Dose-escalation study of single dose mitoxantrone in combination with timed sequential chemotherapy in patients with refractory or relapsing acute myelogenous leukemia.
    Leukemia research, 2000, Volume: 24, Issue:11

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Patient Selection; Recurrence; Ventricular Function, Left

2000
Treatment of childhood acute myelogenous leukemia with allogeneic and autologous stem cell transplantation during the first remission: a report from the Kyushu-Yamaguchi Children's Cancer Study group in Japan.
    Pediatric hematology and oncology, 2000, Volume: 17, Issue:8

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Drug Administration Schedule; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Infant; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Prognosis; Remission Induction; Transplantation, Autologous; Transplantation, Homologous

2000
Chemotherapy for acute myelogenous leukemia in the elderly with cytarabine, mitoxantrone, and granulocyte-macrophage colony-stimulating factor.
    American journal of clinical oncology, 2001, Volume: 24, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Neutrophils

2001
Idarubicin improves blast cell clearance during induction therapy in children with AML: results of study AML-BFM 93. AML-BFM Study Group.
    Leukemia, 2001, Volume: 15, Issue:3

    Topics: Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Child; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Humans; Idarubicin; Leukemia, Myeloid, Acute; Treatment Outcome

2001
Improved treatment results in high-risk pediatric acute myeloid leukemia patients after intensification with high-dose cytarabine and mitoxantrone: results of Study Acute Myeloid Leukemia-Berlin-Frankfurt-Münster 93.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2001, May-15, Volume: 19, Issue:10

    Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Idarubicin; Infant; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Risk Factors; Survival Rate

2001
Combined action of PSC 833 (Valspodar), a novel MDR reversing agent, with mitoxantrone, etoposide and cytarabine in poor-prognosis acute myeloid leukemia.
    Leukemia, 2001, Volume: 15, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporins; Cytarabine; Drug Resistance, Multiple; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone

2001
High remission rate in acute myeloblastic leukemia with only two days of chemotherapy.
    Leukemia & lymphoma, 2001, Volume: 41, Issue:3-4

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents; Cohort Studies; Cytarabine; Cytogenetic Analysis; Drug Administration Schedule; Humans; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Remission Induction; Time Factors; Treatment Outcome

2001
High-dose liposomal daunorubicin and high-dose cytarabine combination in patients with refractory or relapsed acute myelogenous leukemia.
    Cancer, 2001, Jul-01, Volume: 92, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Carriers; Humans; Leukemia, Myeloid, Acute; Liposomes; Middle Aged; Recurrence; Treatment Outcome

2001
Economic analysis of granulocyte colony stimulating factor as adjunct therapy for older patients with acute myelogenous leukemia (AML): estimates from a Southwest Oncology Group clinical trial.
    Cancer investigation, 2001, Volume: 19, Issue:6

    Topics: Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bone Marrow; Costs and Cost Analysis; Cytarabine; Daunorubicin; Disease-Free Survival; Fever; Granulocyte Colony-Stimulating Factor; Hospitalization; Humans; Infections; Leukemia, Myeloid, Acute; Middle Aged; Placebos; Southwestern United States

2001
Intensive timed sequential remission induction chemotherapy with high-dose cytarabine for childhood acute myeloid leukemia.
    Medical and pediatric oncology, 2001, Volume: 37, Issue:4

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Infant; Leukemia, Myeloid, Acute; Male; Remission Induction; Survival Rate; Thioguanine; Time Factors; Treatment Outcome

2001
Mito-flag as salvage therapy for relapsed and refractory acute myeloid leukemia.
    Onkologie, 2001, Volume: 24, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Pilot Projects; Salvage Therapy; Survival Rate; Vidarabine

2001
Intensive chemotherapy followed by allogeneic or autologous stem cell transplantation for patients with myelodysplastic syndromes (MDSs) and acute myeloid leukemia following MDS.
    Blood, 2001, Oct-15, Volume: 98, Issue:8

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Etoposide; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Myelodysplastic Syndromes; Remission Induction; Survival Rate; Time Factors; Transplantation, Autologous; Transplantation, Homologous

2001
Outpatient supportive care following chemotherapy for acute myeloblastic leukemia.
    Leukemia & lymphoma, 2001, Volume: 42, Issue:3

    Topics: Adult; Aged; Analysis of Variance; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Feasibility Studies; Female; Growth Substances; Humans; Inpatients; Leukemia, Myeloid, Acute; Male; Middle Aged; Outpatients; Patient Discharge; Patient Readmission; Remission Induction; Retrospective Studies; Safety; Social Support; Survival Rate; Time Factors; Treatment Outcome

2001
Cytosine arabinoside, idarubicin and divided dose etoposide for the treatment of acute myeloid leukemia in elderly patients.
    Leukemia & lymphoma, 2001, Volume: 42, Issue:3

    Topics: Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Etoposide; Female; Humans; Idarubicin; Infusions, Intravenous; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Platelet Count; Survival Rate

2001
Benefit of cyclosporine modulation of drug resistance in patients with poor-risk acute myeloid leukemia: a Southwest Oncology Group study.
    Blood, 2001, Dec-01, Volume: 98, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Cytarabine; Cytogenetic Analysis; Daunorubicin; Disease-Free Survival; Drug Interactions; Drug Resistance, Neoplasm; Gene Expression; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Risk Factors

2001
Comparison of idarubicin + ara-C-, fludarabine + ara-C-, and topotecan + ara-C-based regimens in treatment of newly diagnosed acute myeloid leukemia, refractory anemia with excess blasts in transformation, or refractory anemia with excess blasts.
    Blood, 2001, Dec-15, Volume: 98, Issue:13

    Topics: Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Humans; Idarubicin; Leukemia, Myeloid, Acute; Prognosis; Recurrence; Remission Induction; Survival Rate; Time Factors; Topotecan; Treatment Failure; Vidarabine

2001
Superior outcome of infant acute myeloid leukemia with intensive chemotherapy: results of the Japan Infant Leukemia Study Group.
    Blood, 2001, Dec-15, Volume: 98, Issue:13

    Topics: Aclarubicin; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 11; Cytarabine; Disease-Free Survival; DNA-Binding Proteins; Doxorubicin; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Histone-Lysine N-Methyltransferase; Humans; Immunophenotyping; Infant; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Myeloid-Lymphoid Leukemia Protein; Prognosis; Proto-Oncogenes; Remission Induction; Survival Rate; Transcription Factors; Translocation, Genetic; Treatment Outcome; Vincristine

2001
Pharmacodynamic modeling of thrombopoietin, platelet, and megakaryocyte dynamics in patients with acute myeloid leukemia undergoing dose intensive chemotherapy.
    Journal of clinical pharmacology, 2002, Volume: 42, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Blood Platelets; Cell Count; Cytarabine; Dose-Response Relationship, Drug; Female; Gene Expression Regulation; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Megakaryocytes; Middle Aged; Thrombopoietin; Time Factors

2002
Outcomes in patients treated with gemtuzumab ozogamicin for relapsed acute myelogenous leukemia.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2002, May-15, Volume: 59, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Aminoglycosides; Anti-Bacterial Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Gemtuzumab; Humans; Infusions, Intravenous; Length of Stay; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Treatment Outcome

2002
Impact of addition of maintenance therapy to intensive induction and consolidation chemotherapy for childhood acute myeloblastic leukemia: results of a prospective randomized trial, LAME 89/91. Leucámie Aiqüe Myéloïde Enfant.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Jun-15, Volume: 20, Issue:12

    Topics: Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Mitoxantrone; Prospective Studies; Recurrence; Treatment Outcome

2002
Feasibility and efficacy of 5-azacytidine used early in the therapy of adult acute nonlymphocytic leukemia: an ECOG pilot study.
    Cancer clinical trials, 1979,Winter, Volume: 2, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Azacitidine; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Infections; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission, Spontaneous; Time Factors

1979
Active immunotherapy in leukemia with neuraminidase-modified leukemic cells.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1977, Issue:62

    Topics: Animals; Antigens, Neoplasm; Clinical Trials as Topic; Cytarabine; Daunorubicin; Humans; Hypersensitivity, Delayed; Immunization; Immunotherapy; Leukemia Virus, Murine; Leukemia, Experimental; Leukemia, Myeloid, Acute; Mice; Mice, Inbred AKR; Mice, Inbred C57BL; Mice, Inbred DBA; Neuraminidase; Tumor Virus Infections

1977
Age and treatment response in acute nonlymphoblastic leukemia.
    Journal of gerontology, 1978, Volume: 33, Issue:1

    Topics: Age Factors; Aged; Antineoplastic Agents; Bone Marrow; Cytarabine; Depression, Chemical; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Prognosis; Thioguanine; Time Factors; Vincristine

1978
Daunomycin, cytosine arabinoside and 6-thioguanine (DAT) vs vincristine, cytosine arabinoside and 6-thioguanine (VAT) in the induction treatment of acute nonlymphocyte leukemia: a randomized collaborative study.
    Medical and pediatric oncology, 1978, Volume: 4, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Agents; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Prednisone; Remission, Spontaneous; Thioguanine; Time Factors; Vincristine

1978
Lithium and granulocytopenia during induction therapy of acute myelogenous leukemia.
    Blood, 1979, Volume: 54, Issue:3

    Topics: Agranulocytosis; Bacterial Infections; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Lithium; Neutropenia; Remission, Spontaneous

1979
The effect of thioguanine on a combination of daunorubicine, cytarabine and prednisone in the treatment of acute leukaemia in adults. The Finnish Leukaemia Group.
    Scandinavian journal of haematology, 1979, Volume: 23, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Aged; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Middle Aged; Prednisone; Prognosis; Remission, Spontaneous; Thioguanine

1979
Chemotherapy and immunotherapy interspersion: clinical studies in acute myeloblastic leukaemia.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1977, Issue:62

    Topics: Adult; Antineoplastic Agents; BCG Vaccine; Clinical Trials as Topic; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Remission, Spontaneous; Skin Tests

1977
Chemotherapy of acute myeloid leukaemia in adults: Medical Research Council.
    British journal of cancer, 1979, Volume: 39, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Child; Child, Preschool; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Middle Aged; Prednisolone; Random Allocation; Thioguanine; Vincristine

1979
Design of adjuvant chemotherapy based on target cell determinants of drug action: possibilities and limitations.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1979, Volume: 67

    Topics: Animals; Antineoplastic Agents; Clinical Trials as Topic; Cytarabine; Drug Evaluation; Humans; Leukemia, Experimental; Leukemia, Myeloid, Acute; Mice; Neoplasms; Research Design

1979
A comparative trial of daunorubicin, cytosine arabinoside, and thioguanine, and a combination of the three agents for the treatment of acute myelocytic leukemia.
    Medical and pediatric oncology, 1979, Volume: 6, Issue:3

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Bone Marrow; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Remission, Spontaneous; Thioguanine

1979
Interhospital differences in the treatment of acute leukaemia in adults. The Finnish Leukaemia Group.
    Scandinavian journal of haematology, 1979, Volume: 23, Issue:2

    Topics: Acute Disease; Adult; Aged; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Finland; Humans; Leukemia; Leukemia, Myeloid, Acute; Middle Aged; Prednisone; Prognosis; Remission, Spontaneous

1979
[Revaluation of the two step DCMP chemotherapy for acute leukemias (author's transl)].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1979, Volume: 20, Issue:10

    Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisolone

1979
Early consolidation chemotherapy for adults with acute leukemia in remission.
    Medical and pediatric oncology, 1976, Volume: 2, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Anti-Bacterial Agents; Antineoplastic Agents; Bacterial Infections; Cytarabine; Enterocolitis, Pseudomembranous; Female; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Necrosis; Prednisone; Remission, Spontaneous; Vincristine

1976
L-asparaginase and prednisolone pretreatment followed by rubidomycin and cytosine arabinoside for induction of remission in adult patients with acute myeloblastic leukaemia.
    Scandinavian journal of haematology, 1975, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Age Factors; Aged; Asparaginase; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Nausea; Prednisolone; Remission, Spontaneous; Vomiting

1975
Comparative study of cytosine arabinoside therapy alone and combined with thioguanine, mercaptopurine, or daunorubicin in acute myelocytic leukemia.
    Cancer, 1975, Volume: 36, Issue:5

    Topics: Adult; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Remission, Spontaneous; Thioguanine; Time Factors

1975
Acute myelogenous leukemia in children: a preliminary report of combination chemotherapy.
    The Journal of pediatrics, 1976, Volume: 88, Issue:1

    Topics: Adolescent; Antineoplastic Agents; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Prednisolone; Remission, Spontaneous; Vincristine

1976
Randomized clinical comparison of daunorubicin (NSC-82151) alone with a combination of daunorubicin, cytosine arabinoside (NSC-63878), 6-thioguanine (NSC-752), and pyrimethamine (NSC-3061) for the treatment of acute nonlymphocytic leukemia.
    Cancer treatment reports, 1976, Volume: 60, Issue:1

    Topics: Acute Disease; Aged; Antineoplastic Agents; Bone Marrow; Central Nervous System Diseases; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Guanazole; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Meninges; Middle Aged; Pyrimethamine; Remission, Spontaneous; Skin Tests; Thioguanine

1976
The effect of immunotherapy on survival of patients with acute myelogenous leukaemia after relapse.
    Haematologia, 1976, Volume: 10, Issue:1

    Topics: Adolescent; Adult; Aged; Antigens, Neoplasm; BCG Vaccine; Child; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission, Spontaneous; Time Factors

1976
Cell kinetics in leukemia. Correlation with clinical features and response to chemotherapy.
    Archives of internal medicine, 1975, Volume: 135, Issue:7

    Topics: Bone Marrow; Bone Marrow Cells; Cytarabine; Daunorubicin; DNA, Neoplasm; Drug Therapy, Combination; Humans; Kinetics; Leucovorin; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Methotrexate; Mitotic Index; Thioguanine

1975
[Letter: Acute myeloblastic leukemia: prevision of the efficiency by the combination of daunorubicin-cytosine-arabinoside].
    La Nouvelle presse medicale, 1975, Jun-07, Issue:23

    Topics: Cells, Cultured; Clinical Trials as Topic; Cytarabine; Daunorubicin; DNA; Drug Evaluation; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Thymidine

1975
[Clinical use of cytosine arabinoside in infancy. I. Cytosine arabinoside in the treatment of acute leukosis].
    Minerva pediatrica, 1975, Sep-15, Volume: 27, Issue:28

    Topics: Acute Disease; Adolescent; Child; Child, Preschool; Clinical Trials as Topic; Cytarabine; Drug Evaluation; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male

1975
AMSA combination chemotherapy in patients with acute myelogenous leukemia unsuitable for standard antileukemic treatment.
    Leukemia & lymphoma, 1992, Volume: 8, Issue:4-5

    Topics: Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Heart Diseases; Humans; Incidence; Infections; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Male; Middle Aged; Remission Induction; Survival Analysis; Thioguanine; Treatment Outcome

1992
Treatment of de novo acute myelogenous leukemia with recombinant granulocyte macrophage-colony-stimulating factor in combination with standard induction chemotherapy: effect of granulocyte macrophage-colony-stimulating factor on white blood cell counts.
    Medical and pediatric oncology. Supplement, 1992, Volume: 2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Monitoring, Physiologic; Recombinant Proteins; Remission Induction; Survival Rate

1992
Current strategies for treatment of acute myeloid leukemia at St Jude Children's Research Hospital.
    Leukemia, 1992, Volume: 6 Suppl 2

    Topics: 2-Chloroadenosine; Acute Disease; Adolescent; Adult; Amsacrine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Child; Child, Preschool; Cladribine; Cytarabine; Daunorubicin; Deoxyadenosines; Etoposide; Humans; Infant; Leukemia, Myeloid, Acute; Remission Induction

1992
Intensive sequential chemotherapy for children with acute myelogenous leukemia: VAPA, 80-035, and HI-C-Daze.
    Leukemia, 1992, Volume: 6 Suppl 2

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Brain; Child; Child, Preschool; Cytarabine; Doxorubicin; Etoposide; Humans; Infant; Leukemia, Myeloid, Acute; Prednisolone; Survival Analysis; Vincristine

1992
Treatment of acute nonlymphocytic leukemia by combination of recombinant human granulocyte colony-stimulating factor and cytotoxic agents: a report of six cases.
    International journal of hematology, 1992, Volume: 55, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Cytarabine; Daunorubicin; Drug Evaluation; Drug Resistance; Drug Synergism; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Immunologic Factors; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Mitoxantrone; Recombinant Proteins; Remission Induction

1992
[Effectiveness of empirical antibiotic therapy in the control of infections in patients with acute leukemia during severe neutropenia].
    Polskie Archiwum Medycyny Wewnetrznej, 1992, Volume: 87, Issue:6

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Bacterial Infections; Cytarabine; Daunorubicin; Female; Humans; Immune Tolerance; Leukemia, Myeloid, Acute; Male; Middle Aged; Neutropenia; Opportunistic Infections; Precursor Cell Lymphoblastic Leukemia-Lymphoma

1992
Homoharringtonine in combination with cytarabine for patients with acute myelogenous leukemia.
    Leukemia, 1992, Volume: 6, Issue:11

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Female; Harringtonines; Homoharringtonine; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence

1992
High-dose cytosine arabinoside for the treatment of acute myeloid leukemia. Studies of the North American Marrow Transplant Group.
    Leukemia, 1992, Volume: 6 Suppl 4

    Topics: Cytarabine; Humans; Leukemia, Myeloid, Acute

1992
[The first Russian trial of treating patients with acute nonlymphoblastic leukemias with novantrone combined with cytosar].
    Terapevticheskii arkhiv, 1992, Volume: 64, Issue:7

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Tolerance; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Pancytopenia; Remission Induction; Russia; Time Factors

1992
[Experience with using aclarubicin in the treatment of acute leukemia and blast crisis of chronic myeloid leukemia].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1992, Volume: 37, Issue:7

    Topics: Aclarubicin; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Cytarabine; Humans; Leukemia; Leukemia, Monocytic, Acute; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction

1992
Long-term outcome of high-dose cytarabine-based consolidation chemotherapy for adults with acute myelogenous leukemia.
    Blood, 1992, Dec-15, Volume: 80, Issue:12

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Daunorubicin; Drug Administration Schedule; Etoposide; Female; Follow-Up Studies; Humans; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Survival Analysis; Time Factors

1992
Use of high-dose cytarabine in autologous bone marrow transplantation in acute myeloid leukemia.
    Leukemia & lymphoma, 1992, Volume: 7 Suppl

    Topics: Adolescent; Adult; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Survival Rate; Transplantation, Autologous

1992
[Effects of alternating as well as long-term intensive polychemotherapy in the remission-maintaining treatment of patients with acute myelocytic leukemia].
    Polskie Archiwum Medycyny Wewnetrznej, 1992, Volume: 87, Issue:2

    Topics: Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Doxorubicin; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Thioguanine; Time Factors

1992
Analysis of treatment failure in acute nonlymphocytic leukemia patients over fifty years of age. A Southwest Oncology Group study.
    American journal of clinical oncology, 1992, Volume: 15, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Examination; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Treatment Outcome

1992
Allogeneic versus autologous bone marrow transplantation (BMT) versus intensive consolidation in acute myelogenous leukemia (AML) in first remission. An EORTC-Gimema phase III trial (AML8 A). The EORTC Leukemia Cooperative Group and the GIMEMA Group.
    Leukemia, 1992, Volume: 6 Suppl 2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Clinical Protocols; Combined Modality Therapy; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Middle Aged; Remission Induction; Survival Analysis; Transplantation, Autologous; Transplantation, Homologous

1992
Treatment results of three consecutive German childhood AML trials: BFM-78, -83, and -87. AML-BFM-Group.
    Leukemia, 1992, Volume: 6 Suppl 2

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child; Child, Preschool; Cranial Irradiation; Cytarabine; Germany, West; Humans; Infant; Leukemia, Myeloid, Acute; Remission Induction; Survival Rate

1992
Mitoxantrone and high dose Ara-C for the treatment of ANLL in childhood: a pilot study of the EORTC CLCG (EORTC 58 872).
    Leukemia, 1992, Volume: 6 Suppl 2

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Drug Administration Schedule; Female; Humans; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Pilot Projects; Remission Induction; Survival Analysis

1992
Treatment of acute non lymphoid leukemia (ANLL) in elderly patients. The GIMEMA experience.
    Leukemia, 1992, Volume: 6 Suppl 2

    Topics: Age Factors; Aged; Aged, 80 and over; Anemia, Aplastic; Antineoplastic Combined Chemotherapy Protocols; Cause of Death; Cytarabine; Daunorubicin; Drug Administration Schedule; Feasibility Studies; Humans; Idarubicin; Infusions, Intravenous; Italy; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Remission Induction; Thioguanine

1992
Short term therapy (STT) for acute myelogenous leukaemia (AML).
    Leukemia, 1992, Volume: 6 Suppl 2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Doxorubicin; Humans; Leukemia, Myeloid, Acute; Middle Aged; Remission Induction; Survival Analysis; Thioguanine; Whole-Body Irradiation

1992
DNA as a carrier for anthracyclines in the treatment of acute myelocytic leukemia (AML).
    Leukemia, 1992, Volume: 6 Suppl 2

    Topics: Adolescent; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; DNA; DNA Adducts; Doxorubicin; Drug Administration Schedule; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Middle Aged; Prednisolone; Prednisone; Survival Analysis; Thioguanine; Vincristine

1992
A randomized study of the efficacy of postconsolidation therapy in adult acute nonlymphocytic leukemia: a report of the Italian Cooperative Group GIMEMA.
    Annals of hematology, 1992, Volume: 64, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Daunorubicin; Etoposide; Humans; Leukemia, Myeloid, Acute; Middle Aged; Remission Induction; Thioguanine; Time Factors

1992
Ceftazidime as initial therapy in febrile patients with acute leukemia during induction chemotherapy. Leukemia Group of Middle Sweden.
    Scandinavian journal of infectious diseases, 1992, Volume: 24, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bacterial Infections; Ceftazidime; Cytarabine; Daunorubicin; Female; Fever; Fever of Unknown Origin; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Thioguanine

1992
High remission rate in acute myeloblastic leukemia in children treated with high-dose methylprednisolone.
    European journal of haematology, 1992, Volume: 48, Issue:4

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Liver; Male; Methylprednisolone; Mitoxantrone; Remission Induction; Spleen; Thioguanine; Vincristine

1992
A phase III trial comparing idarubicin and daunorubicin in combination with cytarabine in acute myelogenous leukemia: a Southeastern Cancer Study Group Study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1992, Volume: 10, Issue:7

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Prospective Studies; Survival Analysis; Treatment Outcome

1992
A randomized study of intermediate versus conventional-dose cytarabine as intensive induction for acute myelogenous leukaemia.
    British journal of haematology, 1992, Volume: 81, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction

1992
Remission induction and postremission therapy in acute myelogenous leukemia: British MRC Study.
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dacarbazine; Daunorubicin; Doxorubicin; Drug Combinations; Etoposide; Humans; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Multicenter Studies as Topic; Nimustine; Prednisone; Randomized Controlled Trials as Topic; Remission Induction; Survival Rate; Thioguanine; United Kingdom; Vincristine

1990
A randomized comparison of intensive maintenance treatment for adult acute myelogenous leukemia using either cyclic alternating drugs or repeated courses of the induction-type chemotherapy: AML-6 trial of the EORTC Leukemia Cooperative Group.
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Belgium; Bone Marrow Transplantation; Child; Combined Modality Therapy; Cytarabine; Daunorubicin; France; Humans; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Vincristine

1990
Preliminary results of intensive therapy of children and adolescents with acute nonlymphocytic leukemia--a Childrens Cancer Study Group report.
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Etoposide; Humans; Infant; Leukemia, Myeloid, Acute; Multicenter Studies as Topic; Pilot Projects; Randomized Controlled Trials as Topic; Remission Induction; Thioguanine; Vincristine

1990
Intermediate-dose Ara-C/m-AMSA for remission induction and high-dose Ara-C/m-AMSA for intensive consolidation in relapsed and refractory adult acute myelogeneous leukemia.
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Germany, West; Humans; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Middle Aged; Randomized Controlled Trials as Topic; Remission Induction; Survival Rate

1990
Postremission chemotherapy for adults with acute myelogenous leukemia: improved survival with high-dose cytarabine and daunorubicin consolidation treatment.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1990, Volume: 8, Issue:7

    Topics: Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Daunorubicin; Doxorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Sex Factors; Survival Analysis

1990
Cytarabine plus idarubicin or daunorubicin as induction and consolidation therapy for previously untreated adult patients with acute myeloid leukemia.
    Blood, 1992, Jan-15, Volume: 79, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Leukocytosis; Male; Middle Aged; Remission Induction

1992
[Autotransplantation in acute nonlymphoid leukemia].
    Haematologica, 1991, Volume: 76 Suppl 3

    Topics: Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Purging; Bone Marrow Transplantation; Busulfan; Carmustine; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Etoposide; Humans; Leukemia, Myeloid, Acute; Remission Induction; Transplantation, Autologous

1991
[Therapy of acute myeloid leukemia in children--results of the AML II/87 multicenter study].
    Kinderarztliche Praxis, 1991, Volume: 59, Issue:11

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Purging; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Survival Analysis; Thioguanine; Transplantation, Autologous; Transplantation, Homologous

1991
Treatment of adult acute myelogenous leukemia: a pilot study at Chulalongkorn Hospital.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 1991, Volume: 74, Issue:7

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cause of Death; Cytarabine; Doxorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Pilot Projects; Remission Induction; Survival Rate; Thailand; Treatment Outcome

1991
Combination of rubidazone and cytosine arabinoside in the treatment of first relapse in acute myelocytic leukemia.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1991, Volume: 2, Issue:6

    Topics: Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Evaluation; Humans; Leukemia, Myeloid, Acute; Middle Aged; Recurrence; Remission Induction

1991
High-dose versus intermediate-dose cytarabine combined with mitoxantrone for the treatment of relapsed and refractory acute myeloid leukemia: results of an age-adjusted randomized comparison.
    Seminars in hematology, 1991, Volume: 28, Issue:3 Suppl 4

    Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Prospective Studies; Recurrence

1991
Improved prognosis of acute nonlymphocytic leukemia in children: results of the 12th-ANLL protocol of Tokyo Children's Cancer Study Group.
    Acta paediatrica Japonica : Overseas edition, 1991, Volume: 33, Issue:4

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Doxorubicin; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Prednisolone; Prognosis; Survival Rate; Treatment Outcome

1991
[Preliminary results of the treatment of acute leukemia with mitoxantrone].
    Acta haematologica Polonica, 1991, Volume: 22, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Female; Humans; Injections, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction

1991
A randomised clinical trial comparing idarubicin and cytarabine to daunorubicin and cytarabine in the treatment of acute non-lymphoid leukaemia. A multicentric study from the Italian Co-operative Group GIMEMA.
    European journal of cancer (Oxford, England : 1990), 1991, Volume: 27, Issue:6

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Thioguanine

1991
The effect of lithium on haematopoiesis of patients with acute myeloid leukaemia.
    Archivum immunologiae et therapiae experimentalis, 1991, Volume: 39, Issue:5-6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Colony-Forming Units Assay; Cytarabine; Doxorubicin; Hematopoiesis; Humans; Leukemia, Myeloid, Acute; Lithium Carbonate

1991
BAVC regimen in CR AML patients.
    Bone marrow transplantation, 1991, Volume: 7 Suppl 2

    Topics: Adolescent; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmustine; Child; Child, Preschool; Cytarabine; Etoposide; Follow-Up Studies; Graft Survival; Humans; Infant; Italy; Leukemia, Myeloid, Acute; Middle Aged; Neoplasm Recurrence, Local; Remission Induction; Survival Rate; Transplantation, Autologous

1991
Allogeneic versus autologous bone marrow transplantation versus chemotherapy for treatment of acute myeloid leukemia in first complete remission (BGM 84 and BGMT 87 studies). The BGMT Group.
    Bone marrow transplantation, 1991, Volume: 7 Suppl 2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Middle Aged; Prospective Studies; Remission Induction; Transplantation, Autologous; Transplantation, Homologous

1991
The use of prophylactic eye drops during high-dose cytosine arabinoside therapy.
    Cancer, 1991, Oct-15, Volume: 68, Issue:8

    Topics: Adult; Aged; Conjunctivitis; Cytarabine; Dexamethasone; Double-Blind Method; Female; Humans; Keratitis; Leukemia, Myeloid, Acute; Male; Middle Aged; Ophthalmic Solutions; Prednisolone

1991
Some reasons for the lack of progress in the treatment of acute myelogenous leukemia: a review of three consecutive trials of the treatment of poor prognosis patients.
    Leukemia research, 1991, Volume: 15, Issue:9

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cell Cycle; Cell Division; Cytarabine; Daunorubicin; Drug Resistance; Humans; Leukemia, Myeloid, Acute; Remission Induction; Treatment Outcome

1991
High-dose cytosine arabinoside as consolidation chemotherapy for acute nonlymphocytic leukemia in remission.
    International journal of hematology, 1991, Volume: 54, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction

1991
A comparison of induction and maintenance therapy for acute nonlymphocytic leukemia in childhood: results of a Pediatric Oncology Group study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1991, Volume: 9, Issue:2

    Topics: Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Child; Child, Preschool; Cytarabine; Daunorubicin; Dexamethasone; DNA Nucleotidylexotransferase; Female; Fever; Humans; Infant; Leukemia, Myeloid, Acute; Male; Multivariate Analysis; Random Allocation; Receptors, Glucocorticoid; Recurrence; Remission Induction; Retrospective Studies; Survival Rate; Thioguanine; Tumor Cells, Cultured; Vincristine

1991
Recombinant human granulocyte-macrophage colony-stimulating factor in combination with standard induction chemotherapy in de novo acute myeloid leukemia.
    Blood, 1991, Feb-15, Volume: 77, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bromodeoxyuridine; Cell Cycle; Cytarabine; Daunorubicin; DNA; Female; Flow Cytometry; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoiesis; Humans; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Neutrophils; Recombinant Proteins

1991
Results of a randomized trial comparing idarubicin and cytosine arabinoside with daunorubicin and cytosine arabinoside in adult patients with newly diagnosed acute myelogenous leukemia.
    Blood, 1991, Apr-15, Volume: 77, Issue:8

    Topics: Adult; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Humans; Idarubicin; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Probability

1991
Long-term outcome of adults with acute myelogenous leukaemia: results of a prospective, randomized study of chemotherapy with a minimal follow-up of 7 years.
    British journal of haematology, 1991, Volume: 77, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Daunorubicin; Etoposide; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prospective Studies; Remission Induction; Thioguanine; Vindesine

1991
Aclarubicin plus cytosine arabinoside versus daunorubicin plus cytosine arabinoside in previously untreated patients with acute myeloid leukemia: a Danish national phase III trial. The Danish Society of Hematology Study Group on AML, Denmark.
    Leukemia, 1991, Volume: 5, Issue:6

    Topics: Aclarubicin; Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Chi-Square Distribution; Cytarabine; Daunorubicin; Denmark; Drug Administration Schedule; Etoposide; Humans; Leukemia, Myeloid, Acute; Middle Aged; Regression Analysis; Remission Induction; Survival Rate

1991
[Intensification of chemotherapy of acute myeloid leukemia in children: report on the studies of the AML-BFM 78 and AML-BFM 83 protocols].
    Gematologiia i transfuziologiia, 1991, Volume: 36, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Etoposide; Germany, West; Humans; Leukemia, Myeloid, Acute; Methotrexate; Prednisone; Prognosis; Remission Induction; Thioguanine; Time Factors; Vincristine

1991
[Treatment of acute nonlymphocytic leukemia].
    Gematologiia i transfuziologiia, 1991, Volume: 36, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Prognosis; Remission Induction; Time Factors

1991
High-dose Ara-C as a single-agent consolidation therapy in childhood acute myelogenous leukemia.
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cross-Sectional Studies; Cytarabine; Down Syndrome; Doxorubicin; Humans; Iceland; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Life Tables; Multicenter Studies as Topic; Preleukemia; Remission Induction; Scandinavian and Nordic Countries; Survival Rate; Thioguanine

1990
Randomized multicenter trial of cytosine arabinoside with mitoxantrone or daunorubicin in previously untreated adult patients with acute nonlymphocytic leukemia (ANLL). Lederle Cooperative Group.
    Leukemia, 1990, Volume: 4, Issue:3

    Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Multicenter Studies as Topic; Remission Induction; Survival Rate

1990
Improved treatment results in the myelocytic subtypes FAB M1-M4 but not in FAB M5 after intensification of induction therapy: results of the German childhood AML studies BFM-78 and BFM-83.
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Daunorubicin; Doxorubicin; Etoposide; Germany, West; Humans; Infant; Leukemia, Myeloid, Acute; Life Tables; Multicenter Studies as Topic; Remission Induction; Thioguanine

1990
Intensive sequential chemotherapy for children with acute myelogenous leukemia.
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Doxorubicin; Humans; Infant; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Life Tables; Multicenter Studies as Topic; Prednisolone; Remission Induction; Survival Rate; United States; Vincristine

1990
Treatment of childhood acute nonlymphocytic leukemia: cooperative Austrian-Hungarian study AML-IGCI-84.
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Aclarubicin; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Austria; Child; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Female; Humans; Hungary; Infant; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Life Tables; Male; Multicenter Studies as Topic; Prednisone; Prospective Studies; Remission Induction; Thioguanine; Vincristine

1990
Therapy of acute myelogenous leukemia in adults.
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Humans; Italy; Leukemia, Myeloid, Acute; Life Tables; Middle Aged; Multicenter Studies as Topic; Prospective Studies; Randomized Controlled Trials as Topic; Remission Induction; Survival Rate; Thioguanine

1990
Consolidation therapy with high-dose cytosine arabinoside: experiences of a prospective study in acute myeloid leukemia.
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Germany, West; Humans; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Life Tables; Middle Aged; Multicenter Studies as Topic; Prospective Studies; Survival Rate

1990
Adult AML: the role of chemotherapy intensity and duration. Two studies of the AML Cooperative Group.
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Daunorubicin; Germany, West; Humans; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Remission Induction; Thioguanine

1990
Comparison of postremission therapies in adult acute myeloid leukemia: preliminary analysis of an ECOG study. Eastern Cooperative Oncology Group.
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Thioguanine; United States

1990
Mitoxantrone, cytosine arabinoside, and VP-16 in 36 patients with relapsed and refractory acute myeloid leukemia.
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Evaluation; Etoposide; Germany, West; Humans; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Multicenter Studies as Topic; Remission Induction; Survival Rate

1990
Effects of verapamil on anthracycline-induced cardiomyopathy: preliminary results of a prospective multicenter trial.
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cardiomyopathies; Cytarabine; Daunorubicin; Hemodynamics; Humans; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Middle Aged; Mitoxantrone; Multicenter Studies as Topic; Prospective Studies; Randomized Controlled Trials as Topic; Thioguanine; Verapamil

1990
Proposal for the classification of relapsed and refractory acute myeloid leukemias as the basis for an age-adjusted randomized comparison of sequentially applied high-dose versus intermediate-dose cytosine arabinoside in combination with mitoxantrone (S-H
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Austria; Child; Cytarabine; Daunorubicin; Drug Resistance; Germany, West; Humans; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Middle Aged; Mitoxantrone; Multicenter Studies as Topic; Neoplasm Recurrence, Local; Prospective Studies; Randomized Controlled Trials as Topic; Thioguanine

1990
Autologous bone marrow transplantation in acute myeloid leukemia in first remission: first Dutch prospective study.
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Middle Aged; Multicenter Studies as Topic; Netherlands; Prospective Studies; Survival Rate; Thioguanine; Transplantation, Autologous; Transplantation, Homologous

1990
Identification of two risk groups in childhood acute myelogenous leukemia after therapy intensification in study AML-BFM-83 as compared with study AML-BFM-78. AML-BFM Study Group.
    Blood, 1990, May-15, Volume: 75, Issue:10

    Topics: Adolescent; Child; Child, Preschool; Cytarabine; Daunorubicin; Etoposide; Female; Germany; Humans; Leukemia, Myeloid, Acute; Male; Multicenter Studies as Topic; Multivariate Analysis; Prognosis; Risk Factors

1990
Treatment of acute myeloid leukemia in elderly patients: the influence of maintenance therapy (BGM 84 protocol).
    Nouvelle revue francaise d'hematologie, 1990, Volume: 32, Issue:2

    Topics: Aclarubicin; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Multicenter Studies as Topic; Survival Rate

1990
Cure of acute myelocytic leukemia in adults: a reality.
    Leukemia, 1990, Volume: 4, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Middle Aged; Randomized Controlled Trials as Topic; Remission Induction

1990
Sequential intermediate-dose cytosine arabinoside and mitoxantrone for patients with relapsed and refractory acute myelocytic leukemia.
    American journal of hematology, 1990, Volume: 35, Issue:1

    Topics: Adult; Aged; Clinical Trials as Topic; Cytarabine; Delayed-Action Preparations; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Pilot Projects; Recurrence; Remission Induction; Time Factors

1990
Chemotherapy of adult acute nonlymphoblastic leukaemia.
    Haematologia, 1990, Volume: 23, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Doxorubicin; Etoposide; Female; Humans; Immunotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitolactol; Prospective Studies; Randomized Controlled Trials as Topic; Remission Induction; Survival Rate; Tamoxifen

1990
The role of timing of high-dose cytosine arabinoside intensification and of maintenance therapy in the treatment of children with acute nonlymphocytic leukemia.
    Cancer, 1990, Sep-15, Volume: 66, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cytarabine; Daunorubicin; Dexamethasone; Drug Administration Schedule; Etoposide; Female; Humans; Infant; Infant, Newborn; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Multicenter Studies as Topic; Pilot Projects; Random Allocation; Remission Induction; Thioguanine

1990
High-dose cytosine arabinoside and amsacrine or mitoxantrone in relapsed and refractory acute myeloid leukaemia: a prospective randomized study.
    European journal of haematology, 1990, Volume: 45, Issue:3

    Topics: Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Prospective Studies; Survival Rate

1990
High-dose cytosine arabinoside plus etoposide as initial treatment for acute myeloid leukaemia: a single centre study.
    British journal of cancer, 1990, Volume: 62, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

1990
Therapy of acute myelogenous leukemia in patients over the age of 50: a randomized Southeastern Cancer Study Group trial.
    Leukemia research, 1990, Volume: 14, Issue:10

    Topics: Aged; Aged, 80 and over; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Survival Rate; Thioguanine; United States

1990
Treatment of myelodysplastic syndromes with retinoic acid and 1 alpha-hydroxy-vitamin D3 in combination with low-dose ara-C is not superior to ara-C alone. Results from a randomized study. The Scandinavian Myelodysplasia Group (SMG).
    European journal of haematology, 1990, Volume: 45, Issue:5

    Topics: Aged; Aged, 80 and over; Cytarabine; Drug Therapy, Combination; Female; Humans; Hydroxycholecalciferols; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Tretinoin

1990
High-dose versus intermediate-dose cytosine arabinoside in combination with mitoxantrone for the treatment of relapsed and refractory acute myeloid leukemia--preliminary clinical and pharmacological data of a randomized comparison.
    Cancer treatment reviews, 1990, Volume: 17, Issue:2-3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Cytarabine; Humans; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Recurrence

1990
Low-dose cytarabine versus intensive chemotherapy in the treatment of acute nonlymphocytic leukemia in the elderly.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1990, Volume: 8, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Bone Marrow; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Prognosis; Random Allocation; Remission Induction

1990
Etoposide in acute nonlymphocytic leukemia. Australian Leukemia Study Group.
    Blood, 1990, Jan-01, Volume: 75, Issue:1

    Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Humans; Leukemia, Myeloid, Acute; Middle Aged; Multicenter Studies as Topic; Survival Analysis

1990
Intensive induction and consolidation chemotherapy for adults and children with acute myeloid leukaemia (AML) joint AML trial 1982-1985.
    Haematology and blood transfusion, 1987, Volume: 30

    Topics: Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Child; Clinical Trials as Topic; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Random Allocation; Remission Induction; Risk; Thioguanine; United Kingdom

1987
The ninth British Medical Research Council trial for the treatment of acute myeloid leukaemia.
    Haematology and blood transfusion, 1987, Volume: 30

    Topics: Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Combinations; England; Etoposide; Humans; Leukemia, Myeloid, Acute; Prednisone; Remission Induction; Thioguanine; Vincristine

1987
Improvement in outcome for children with acute nonlymphocytic leukemia. A report from the Childrens Cancer Study Group.
    Cancer, 1989, Apr-15, Volume: 63, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Infant; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Prednisolone; Prognosis; Remission Induction; Thioguanine; Vincristine

1989
[Treatment of acute myeloblastic leukemia in aged patients].
    Presse medicale (Paris, France : 1983), 1989, Mar-11, Volume: 18, Issue:10

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colony-Stimulating Factors; Cytarabine; Daunorubicin; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Middle Aged; Palliative Care; Prognosis

1989
Bone marrow transplantation for the treatment of leukaemia-results of the Munich Cooperative Group.
    Folia haematologica (Leipzig, Germany : 1928), 1989, Volume: 116, Issue:3-4

    Topics: Adolescent; Adult; Bone Marrow Transplantation; Carmustine; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Female; Germany, West; Graft vs Host Disease; Humans; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Middle Aged; Multicenter Studies as Topic; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Survival Rate; Whole-Body Irradiation

1989
[AML-6 study of the value of cyclic alternating chemotherapy during remission in acute myelocytic leukemia].
    Onkologie, 1985, Volume: 8, Issue:2

    Topics: Adult; Aminoacridines; Amsacrine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Administration Schedule; Humans; Leukemia, Myeloid, Acute; Middle Aged; Vincristine

1985
Treatment of relapsed acute myeloid leukemia with idarubicin and intermediate-dose cytarabine.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1989, Volume: 7, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Remission Induction

1989
Low-dose ara-C therapy for acute myelogenous leukemia in elderly patients.
    Leukemia, 1989, Volume: 3, Issue:1

    Topics: Aged; Aging; Clinical Trials as Topic; Cytarabine; Drug Administration Schedule; Female; Granulocytes; Hemorrhage; Humans; Infections; Injections, Subcutaneous; Leukemia, Myeloid, Acute; Leukopenia; Male; Middle Aged; Prospective Studies; Remission Induction; Thrombocytopenia

1989
High-dose Ara-C (HiDAC) plus asparaginase in elderly patients with acute non-lymphocytic leukemia: a pilot multicentric study by the Italian Cooperative Group GIMEMA.
    European journal of haematology, 1989, Volume: 42, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Clinical Trials as Topic; Cytarabine; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Italy; Leukemia, Myeloid, Acute; Male; Middle Aged

1989
Alternating v repeated postremission treatment in adult acute myelogenous leukemia: a randomized phase III study (AML6) of the EORTC Leukemia Cooperative Group.
    Blood, 1989, Volume: 73, Issue:4

    Topics: Adolescent; Adult; Aged; Amsacrine; Child; Clinical Trials as Topic; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Middle Aged; Random Allocation; Remission Induction

1989
A phase-three trial comparing daunorubicin or idarubicin combined with cytosine arabinoside in acute myelogenous leukemia.
    Seminars in oncology, 1989, Volume: 16, Issue:1 Suppl 2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Random Allocation; Remission Induction

1989
Use of the day 6 bone marrow to alter remission induction therapy in patients with acute myeloid leukaemia: a leukemia intergroup study.
    British journal of haematology, 1989, Volume: 71, Issue:4

    Topics: Adult; Antibiotics, Antineoplastic; Bone Marrow Transplantation; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Multicenter Studies as Topic; Prognosis; Remission Induction; Time Factors

1989
Results of the Italian AIEOP/LAM 8204 study for the treatment of childhood AML: an update.
    Bone marrow transplantation, 1989, Volume: 4 Suppl 1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Clinical Trials as Topic; Cytarabine; Daunorubicin; Humans; Infant; Italy; Leukemia, Myeloid, Acute; Multicenter Studies as Topic; Remission Induction; Thioguanine

1989
A randomized comparison of post-consolidation therapy in acute non-lymphoid leukaemia: a study of the Italian cooperative group GIMEMA.
    Bone marrow transplantation, 1989, Volume: 4 Suppl 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Evaluation; Humans; Italy; Leukemia, Myeloid, Acute; Multicenter Studies as Topic; Random Allocation; Remission Induction; Thioguanine

1989
High dose cytarabine in acute myelogenous leukemia.
    Bone marrow transplantation, 1989, Volume: 4 Suppl 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Humans; Leukemia, Myeloid, Acute; Remission Induction

1989
Amsacrine, cytarabine and thioguanine (AAT) versus daunorubicin, cytarabine, thioguanine (DAT) in adults with untreated acute non-lymphoblastic leukemia (ANLL). Austrian-German results.
    Onkologie, 1989, Volume: 12, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Middle Aged; Random Allocation; Thioguanine

1989
Age related randomized comparison of sequentially applied high-dose versus intermediate dose cytosine arabinoside in combination with mitoxantrone (S-HAM) in the treatment of relapsed and refractory acute myeloid leukemia: study design and preliminary res
    Onkologie, 1989, Volume: 12, Issue:1

    Topics: Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Random Allocation

1989
[Advances in the treatment of acute myeloid leukemia in children. Experience of the Argentinian Group of Acute Leukemia Treatment and the Latin American Group of Malignant Hemopathies Treatment 1967-1987].
    Sangre, 1989, Volume: 34, Issue:3

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Evaluation Studies as Topic; Humans; Infant; Leukemia, Myeloid, Acute; Methotrexate; Prednisolone; Prednisone; Thioguanine; Vincristine

1989
[Complete 8-year remission of acute myeloblastic leukemia in 2 children].
    Pediatriia, 1989, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Prednisone; Remission Induction; Time Factors; Vincristine

1989
A two-step timed sequential treatment for acute myelocytic leukemia.
    Blood, 1989, Volume: 74, Issue:5

    Topics: Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Administration Schedule; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Middle Aged

1989
Remission induction in children with acute non-lymphocytic leukemia using cytosine arabinoside and doxorubicin or daunorubicin: a report from the Childrens Cancer Study Group.
    Medical and pediatric oncology, 1989, Volume: 17, Issue:5

    Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Clinical Trials as Topic; Cytarabine; Daunorubicin; Doxorubicin; Humans; Leukemia, Myeloid, Acute; Remission Induction; Survival Analysis

1989
High dose cytosine arabinoside in the treatment of adult acute myelogenous leukaemia.
    Bone marrow transplantation, 1989, Volume: 4 Suppl 3

    Topics: Adult; Clinical Trials as Topic; Cytarabine; Humans; Leukemia, Myeloid, Acute

1989
Idarubicin in acute leukemia: results of US trials.
    Bone marrow transplantation, 1989, Volume: 4 Suppl 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Evaluation; Humans; Idarubicin; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute

1989
Results of chemotherapy for unselected patients with acute myeloblastic leukaemia: effect of exclusions on interpretation of results. The Toronto Leukemia Study Group.
    Lancet (London, England), 1986, Apr-05, Volume: 1, Issue:8484

    Topics: Administration, Oral; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Administration Schedule; Evaluation Studies as Topic; Humans; Infusions, Parenteral; Injections, Subcutaneous; Leukemia, Myeloid, Acute; Prognosis; Random Allocation; Thioguanine

1986
Principal results of the Medical Research Council's 8th acute myeloid leukaemia trial.
    Lancet (London, England), 1986, Nov-29, Volume: 2, Issue:8518

    Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Central Nervous System Diseases; Child; Child, Preschool; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Administration Schedule; Humans; Infant; Leukemia, Myeloid, Acute; Middle Aged; Neoplasm Recurrence, Local; Neoplasms; Prognosis; Random Allocation; Thioguanine

1986
Comparative trial of cytarabine and thioguanine in combination with amsacrine or daunorubicin in patients with untreated acute nonlymphocytic leukemia: results of the L-16M protocol.
    Leukemia, 1989, Volume: 3, Issue:2

    Topics: Age Factors; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Humans; Leukemia, Myeloid, Acute; Prognosis; Thioguanine

1989
Idarubicin in acute leukemias: experience of the Italian Cooperative Group GIMEMA.
    Seminars in oncology, 1989, Volume: 16, Issue:1 Suppl 2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Female; Humans; Idarubicin; Leukemia; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Random Allocation; Remission Induction

1989
A multicenter trial of cytarabine plus idarubicin or daunorubicin as induction therapy for adult nonlymphocytic leukemia.
    Seminars in oncology, 1989, Volume: 16, Issue:1 Suppl 2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Remission Induction

1989
Idarubicin in acute leukemia: results of studies at Memorial Sloan-Kettering Cancer Center.
    Seminars in oncology, 1989, Volume: 16, Issue:1 Suppl 2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Cytarabine; Daunorubicin; Female; Humans; Idarubicin; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Remission Induction

1989
[Results of the treatment of non-lymphoblastic leukemia with small doses of cytosine arabinoside].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1988, Mar-14, Volume: 43, Issue:11

    Topics: Adult; Aged; Clinical Trials as Topic; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction

1988
Extension of remission in acute nonlymphocytic leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1988, Volume: 6, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Humans; Leukemia, Myeloid, Acute; Remission Induction; Thioguanine

1988
[Results of treating acute myeloid leukemia resistant to conventional chemotherapy with moderately large doses of cytarabine and etoposide].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1988, Nov-21, Volume: 43, Issue:47

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Drug Resistance; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction

1988
Synergy between high-dose cytarabine and asparaginase in the treatment of adults with refractory and relapsed acute myelogenous leukemia--a Cancer and Leukemia Group B Study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1988, Volume: 6, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosyluracil; Asparaginase; Cytarabine; Humans; Leukemia, Myeloid, Acute

1988
Allogeneic bone marrow transplantation versus intensification chemotherapy for acute myelogenous leukaemia in first remission: a prospective controlled trial.
    British journal of haematology, 1988, Volume: 68, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Clinical Trials as Topic; Cytarabine; Doxorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Probability; Prospective Studies; Remission Induction

1988
High-dose cytosine arabinoside and mitoxantrone: preliminary results of a pilot study with sequential application (S-HAM) indicating a high antileukemic activity in refractory acute leukemias.
    Onkologie, 1988, Volume: 11, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Pilot Projects

1988
Intensive maintenance treatment in acute myelogenous leukemia (AML): single institution experience of a multicenter randomized trial.
    Onkologie, 1988, Volume: 11, Issue:1

    Topics: Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Cytosine; Daunorubicin; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Leukemia, Myeloid, Acute; Middle Aged; Random Allocation; Vincristine

1988
A multicentre study on intensive induction and consolidation therapy in acute myelogenous leukaemia.
    Blut, 1988, Volume: 56, Issue:5

    Topics: Actuarial Analysis; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Etoposide; Humans; Infections; Leukemia, Myeloid, Acute; Middle Aged; Neutropenia; Remission Induction; Thrombocytopenia

1988
Prolonged high dose ARA-C infusions in acute leukemia.
    Leukemia, 1988, Volume: 2, Issue:5

    Topics: Adult; Aged; Clinical Trials as Topic; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Time Factors

1988
[Alternatives and further development of therapy of acute myeloid leukemia in adults. Update of West German multicenter studies].
    Onkologie, 1987, Volume: 10, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Combined Modality Therapy; Cytarabine; Humans; Immunotherapy; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Random Allocation; Remission Induction

1987
[High dosage ARA-C in combination with mitoxantrone in therapy of acute myeloid leukemia in childhood. Initial results of the AML BFM-85 recurrence study].
    Onkologie, 1987, Volume: 10, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Clinical Trials as Topic; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid, Acute; Mitoxantrone

1987
Therapeutic strategies in acute myelocytic leukemia: a status report of the experience of CALGB. Cancer and Leukemia Group B.
    Haematology and blood transfusion, 1987, Volume: 30

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Combinations; Humans; Leukemia, Myeloid, Acute; Remission Induction; Sulfamethoxazole; Time Factors; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; United States

1987
Phase I/II trial of high-dose cytosine arabinoside and mitoxantrone in adult refractory acute myeloid leukemia.
    Haematology and blood transfusion, 1987, Volume: 30

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Drug Administration Schedule; Germany, West; Humans; Leukemia, Myeloid, Acute; Mitoxantrone

1987
Remission induction with cytarabine and daunorubicin with or without 6-thioguanine in adult patients with acute myelocytic leukemia.
    Haematology and blood transfusion, 1987, Volume: 30

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Remission Induction; Thioguanine

1987
Long-term results of two Swiss AML studies.
    Haematology and blood transfusion, 1987, Volume: 30

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Female; Humans; Immunization; Leukemia, Myeloid, Acute; Male; Switzerland; Vincristine

1987
Aclacinomycin-A in the induction treatment of childhood acute myelogenous leukemia.
    Haematology and blood transfusion, 1987, Volume: 30

    Topics: Aclarubicin; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Clinical Trials as Topic; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Naphthacenes; Prospective Studies; Remission Induction

1987
Remission induction and maintenance modalities in acute myeloid leukemia: a multicenter randomized study.
    Haematology and blood transfusion, 1987, Volume: 30

    Topics: Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Daunorubicin; France; Humans; Leukemia, Myeloid, Acute; Random Allocation; Remission Induction; Time Factors

1987
Postinduction and preremission chemotherapy alternatives for adult AML: three multicenter studies of the AML Cooperative Group.
    Haematology and blood transfusion, 1987, Volume: 30

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Germany, West; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Random Allocation; Remission Induction; Thioguanine

1987
Neuraminidase-treated allogeneic blasts for maintenance in acute myelogenous leukemia: results of a prospective randomized trial.
    Haematology and blood transfusion, 1987, Volume: 30

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Combined Modality Therapy; Cytarabine; Daunorubicin; Germany, West; Humans; Immunization; Leukemia, Myeloid, Acute; Neuraminidase; Prospective Studies; Random Allocation; Remission Induction; Thioguanine

1987
The childhood AML studies BFM-78 and -83: treatment results and risk factor analysis.
    Haematology and blood transfusion, 1987, Volume: 30

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Etoposide; Germany, West; Humans; Leukemia, Myeloid, Acute; Methotrexate; Prednisone; Prognosis; Remission Induction; Risk; Thioguanine; Vincristine

1987
Improved treatment results in childhood acute nonlymphoblastic leukemia with the BFM-AML protocol 78 in a multicenter study in the GDR.
    Haematology and blood transfusion, 1987, Volume: 30

    Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Child; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Doxorubicin; Germany, East; Humans; Leukemia, Myeloid, Acute; Methotrexate; Prednisone; Remission Induction; Thioguanine; Vincristine

1987
A comparison of cytokinetically based versus intensive chemotherapy for childhood acute myelogenous leukemia.
    Haematology and blood transfusion, 1987, Volume: 30

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Cytarabine; Daunorubicin; Etoposide; Humans; Leukemia, Myeloid, Acute; Remission Induction; Vincristine

1987
The treatment of acute myelogenous leukemia.
    Haematology and blood transfusion, 1987, Volume: 31

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Doxorubicin; Humans; Leukemia, Myeloid, Acute; Middle Aged; Random Allocation; Thioguanine

1987
Short-term therapy for acute myelogenous leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1988, Volume: 6, Issue:2

    Topics: Actuarial Analysis; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Doxorubicin; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction

1988
Comparison of 1 + 5 DAT and 3 + 10 DAT followed by COAP or MAZE consolidation therapy in the treatment of acute myeloid leukemia: MRC ninth AML trial.
    Seminars in oncology, 1987, Volume: 14, Issue:2 Suppl 1

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Etoposide; Humans; Leukemia, Myeloid, Acute; Middle Aged; Prednisolone; Thioguanine; Vincristine

1987
Results of induction and consolidation treatment with intermediate and high-dose ara-C and m-AMSA containing regimens in patients with primarily failed or relapsed acute leukemia and non-Hodgkin's lymphoma.
    Scandinavian journal of haematology. Supplementum, 1986, Volume: 44

    Topics: Adolescent; Adult; Aminoacridines; Amsacrine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Follow-Up Studies; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma; Middle Aged

1986
Randomized trial of high-dose cytarabine versus amsacrine in acute myelogenous leukemia in relapse: a Leukemia Intergroup Study.
    Cancer treatment reports, 1986, Volume: 70, Issue:4

    Topics: Adolescent; Adult; Aged; Aminoacridines; Amsacrine; Antibiotics, Antineoplastic; Bone Marrow; Clinical Trials as Topic; Cytarabine; Drug Resistance; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Naphthacenes; Random Allocation

1986
[Risk groups in acute, non-lymphatic leukemia in childhood. Analysis of the results of the cooperative therapeutic studies AML-BFM 78 and 83].
    Onkologie, 1986, Volume: 9, Issue:2

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Clinical Trials as Topic; Combined Modality Therapy; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Prognosis; Risk; Thioguanine

1986
A randomized comparison of maintenance treatment with androgens, immunotherapy, and chemotherapy in adult acute myelogenous leukemia. A Leukemia-Lymphoma Group Trial of the EORTC.
    Cancer, 1986, Aug-01, Volume: 58, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Clinical Trials as Topic; Combined Modality Therapy; Cytarabine; Daunorubicin; Doxorubicin; Humans; Immunotherapy; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Middle Aged; Prospective Studies; Random Allocation; Testosterone Congeners; Thioguanine; Time Factors; Vincristine

1986
Amsacrine: a review.
    Leukemia research, 1986, Volume: 10, Issue:11

    Topics: Amsacrine; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Evaluation; Drug Resistance; Humans; Leukemia, Experimental; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma

1986
A new regimen of amsacrine with high-dose cytarabine is safe and effective therapy for acute leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Clinical Trials as Topic; Cytarabine; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged

1987
High-dose cytosine arabinoside in the treatment of acute myelogenous leukemia: contributions to outcome of clinical and laboratory attributes.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Clinical Trials as Topic; Cytarabine; Doxorubicin; Drug Combinations; Humans; Leukemia, Myeloid, Acute; Middle Aged; Neoplastic Stem Cells; Phenotype; Remission Induction; Statistics as Topic; Sulfamethoxazole; Thioguanine; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Tumor Stem Cell Assay

1987
Influence of daunorubicin and cytarabine sequencing on the outcome of therapy in acute myelogenous leukemia: a randomized trial.
    Cancer treatment reports, 1987, Volume: 71, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Random Allocation; Statistics as Topic; Thioguanine

1987
Treatment of acute myelogenous leukemia. A prospective controlled trial of bone marrow transplantation versus consolidation chemotherapy.
    Annals of internal medicine, 1985, Volume: 102, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Clinical Trials as Topic; Cytarabine; Daunorubicin; Female; HLA Antigens; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Thioguanine

1985
Low-dose ARA-C fails to enhance differentiation of leukaemic cells.
    British journal of haematology, 1985, Volume: 59, Issue:4

    Topics: Adult; Aged; Bone Marrow; Clinical Trials as Topic; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

1985
[AML-7 study of the value of intensive remission induction in aged patients with acute myelocytic leukemia].
    Onkologie, 1985, Volume: 8, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Administration Schedule; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Vincristine

1985
High rate of long-term survival in adult acute leukemia following ten-day chemotherapy (OAP) induction. Maintenance with chemotherapy or chemotherapy plus BCG vaccine.
    Archives of internal medicine, 1985, Volume: 145, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Clinical Trials as Topic; Cytarabine; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisone; Random Allocation; Sex Factors; Time Factors; Vincristine

1985
Treatment of acute myelocytic leukemia with a daunorubicin-cytarabine-6 thioguanine regimen without maintenance therapy.
    Onkologie, 1985, Volume: 8, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Thioguanine

1985
Immunotherapy with allogeneic neuraminidase-treated blasts for maintenance in acute myelogenous leukemia (AML). Significant prolongation of remission duration in patients receiving at least 3 cycles of therapy.
    Onkologie, 1985, Volume: 8, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Administration Schedule; Humans; Immunotherapy; Leukemia, Myeloid, Acute; Prospective Studies; Random Allocation; Thioguanine

1985
[AML-6 and AML-7 studies on the treatment of acute myelocytic leukemia. Cyclic alternating chemotherapy during remission, and induction of remission and survival of elderly patients].
    Onkologie, 1985, Volume: 8, Issue:3

    Topics: Adult; Age Factors; Aged; Aminoacridines; Amsacrine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azaguanine; Cytarabine; Daunorubicin; Drug Administration Schedule; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Middle Aged; Vincristine

1985
Intensified induction and consolidation with or without maintenance chemotherapy for acute myeloid leukemia (AML): two multicenter studies of the German AML Cooperative Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1985, Volume: 3, Issue:12

    Topics: Actuarial Analysis; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Germany, West; Humans; Leukemia, Myeloid, Acute; Middle Aged; Pilot Projects; Random Allocation; Thioguanine; Time Factors

1985
Fetal liver infusion: an adjuvant in the therapy of acute myeloid leukemia (AML).
    Progress in clinical and biological research, 1985, Volume: 193

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Blood Transfusion; Cell Survival; Clinical Trials as Topic; Combined Modality Therapy; Cytarabine; Daunorubicin; Erythrocyte Transfusion; Female; Fetus; Humans; Leukemia, Myeloid, Acute; Liver; Liver Transplantation; Male; Middle Aged; Pregnancy

1985
Central nervous system toxicity of high-dose cytosine arabinoside.
    Seminars in oncology, 1985, Volume: 12, Issue:2 Suppl 3

    Topics: Adolescent; Adult; Aged; Central Nervous System Diseases; Cerebellar Diseases; Clinical Trials as Topic; Cytarabine; Dose-Response Relationship, Drug; Drug Evaluation; Epilepsy, Tonic-Clonic; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma; Male; Middle Aged; Nystagmus, Pathologic; Syndrome; Tremor

1985
Prolonging remission in myeloblastic leukemia by tice-strain bacillus Calmette-Guérin.
    Lancet (London, England), 1974, Jul-20, Volume: 2, Issue:7873

    Topics: Administration, Oral; Adolescent; Adult; BCG Vaccine; Cyclophosphamide; Cytarabine; Daunorubicin; Humans; Immunotherapy; Injections, Intravenous; Leukemia, Myeloid, Acute; Methotrexate; Middle Aged; Remission, Spontaneous; Thioguanine; Time Factors; Vincristine

1974
Immunotherapy for acute myelogenous leukaemia.
    British journal of cancer, 1973, Volume: 28, Issue:5

    Topics: Adolescent; Adult; BCG Vaccine; Cytarabine; Daunorubicin; Female; Histocompatibility Testing; Humans; Immunity; Immunotherapy; Injections, Intradermal; Leukemia, Myeloid, Acute; Lymphocyte Activation; Lymphocytes; Male; Middle Aged; Plicamycin; Remission, Spontaneous; Statistics as Topic; Time Factors

1973
Management of adult acute myelogenous leukaemia.
    British medical journal, 1973, Jan-20, Volume: 1, Issue:5846

    Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents; BCG Vaccine; Blood Cell Count; Blood Platelets; Child; Cytarabine; Daunorubicin; Humans; Immunotherapy; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Middle Aged; Remission, Spontaneous; Thioguanine

1973
A comparative trial of remission induction (by cytosine arabinoside, or C.A.R. and thioguanine, or C.A.R. and daunorubicine) and maintenance therapy (by C.A.R. or methylgag) in acute myeloid leukaemia.
    Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1973, Volume: 18, Issue:3

    Topics: Adolescent; Adult; Aged; Amidines; Antineoplastic Agents; Child; Cytarabine; Daunorubicin; Drug Therapy, Combination; Evaluation Studies as Topic; Glyoxal; Humans; Hydrazones; Leukemia, Myeloid, Acute; Middle Aged; Remission, Spontaneous; Thioguanine

1973
Cytarabine for acute leukemia in adults. Effect of schedule on therapeutic response.
    Archives of internal medicine, 1974, Volume: 133, Issue:2

    Topics: Acute Disease; Adult; Blood Cell Count; Blood Platelets; Cytarabine; Female; Hemoglobinometry; Humans; Infusions, Parenteral; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Regression, Spontaneous; Remission, Spontaneous; Sex Factors; Time Factors

1974
Chemotherapy of acute leukemia. Comparison of cytarabine alone and in combination with vincristine, prednisone, and cyclophosphamide.
    Archives of internal medicine, 1974, Volume: 133, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Anemia; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocyte Count; Leukopenia; Male; Middle Aged; Nausea; Prednisone; Time Factors; Vincristine; Vomiting

1974
Combination chemotherapy of acute leukaemia in adults. Comparison of two schedules.
    Scandinavian journal of haematology, 1974, Volume: 12, Issue:5

    Topics: Administration, Oral; Adult; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Prognosis

1974
A second comparative trial of remission induction (by cytosine arabinoside given every 12 hours, or C.A.R. and thioguanine, or C.A.R. and daunorubicine) and maintenance therapy (by C.A.R. or methylgag) in acute myeloid leukaemia.
    European journal of cancer, 1974, Volume: 10, Issue:7

    Topics: Bone Marrow Examination; Cytarabine; Daunorubicin; Drug Therapy, Combination; Guanidines; Humans; Intensive Care Units; Leukemia, Myeloid, Acute; Leukocyte Count; Mitoguazone; Remission, Spontaneous; Thioguanine; Time Factors

1974
[Treatment of acute leukemia. Controlled clinical trials and experimental data with a view to a more rational administration of anti-leukemic drugs].
    Revue medicale de Liege, 1973, Jun-15, Volume: 28, Issue:12

    Topics: Clinical Trials as Topic; Cytarabine; Daunorubicin; DNA, Neoplasm; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate; Prednisolone; Vincristine

1973
Treatment of acute myeloid leukaemia with daunorubicin, cytosine arabinoside, mercaptopurine, L-asparaginase, prednisone and thioguanine: results of treatment with five multiple-drug schedules. Report of the Medical Research Council's Working Party on Leu
    British journal of haematology, 1974, Volume: 27, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Asparaginase; Blood Platelets; Child; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Leukocyte Count; Lymphocytes; Male; Mercaptopurine; Middle Aged; Prednisone; Prognosis; Remission, Spontaneous; Thioguanine; Thrombocytopenia

1974
[Results in the treatment of acute granulocytic leukemias using a combination of daunorubicine-cytosine arabinoside-cyclophosphamide. Apropos of 35 cases].
    Lille medical : journal de la Faculte de medecine et de pharmacie de l'Universite de Lille, 1974, Volume: 19, Issue:3

    Topics: Adolescent; Adult; Child; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Drug Tolerance; Female; Glycosides; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged

1974
Combination of arabinosyl cytsone, methylglyoxal bis (guanylhydrazone), 6-mercaptopurine and prednisone in the treatment of acute myelocytic leukemia.
    European journal of cancer, 1969, Volume: 5, Issue:3

    Topics: Adult; Antineoplastic Agents; Child; Clinical Trials as Topic; Cytarabine; Drug Synergism; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Prednisone

1969
Combination chemotherapy using L-asparaginase, daunorubicin, and cytosine arabinoside in adults with acute myelogenous leukaemia.
    British medical journal, 1970, Nov-28, Volume: 4, Issue:5734

    Topics: Adolescent; Adult; Aged; Asparaginase; Blood Cell Count; Clinical Trials as Topic; Cytarabine; Daunorubicin; Edema; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Nausea; Serum Albumin; Vomiting

1970
Clinical trials of 1-beta-D-arabinofuranosyl cytosine and 1,3-bis-(2-chloroethyl)-1-nitrosourea combination in metastatic cancer and acute leukemia.
    Cancer, 1971, Volume: 27, Issue:5

    Topics: Age Factors; Blood Cell Count; Blood Platelets; Blood Urea Nitrogen; Clinical Trials as Topic; Cytarabine; Drug Synergism; Female; Hemoglobins; Humans; Injections, Intravenous; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Neoplasm Metastasis; Neoplasms; Nitrogen Mustard Compounds; Nitroso Compounds; Nitrosourea Compounds; Remission, Spontaneous; Reticulocytes; Sex Factors; Urea; Uric Acid

1971
The chemotherapy of human and animal acute leukemia.
    Cancer chemotherapy reports, 1971, Volume: 55, Issue:4

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Asparaginase; Azaserine; Cell Division; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Disease Models, Animal; Drug Combinations; Humans; Kinetics; Leukemia L1210; Leukemia, Experimental; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Neoplasms; Prednisone; Remission, Spontaneous; RNA, Neoplasm; Vincristine

1971

Other Studies

2739 other study(ies) available for cytarabine and Acute Myelogenous Leukemia

ArticleYear
Guanosine diphosphate-L-fucose plasma: N-acetylglucosaminide fucosyltransferase as in index of bone marrow hyperplasia after chemotherapy.
    Cancer research, 1978, Volume: 38, Issue:1

    Topics: Antineoplastic Agents; Bone Marrow; Guanosine Diphosphate Fucose; Hexosyltransferases; Humans; Hyperplasia; Leukemia, Myeloid, Acute; Lymphoma; Remission, Spontaneous

1978
Levels of two plasma fucosyltransferases as an index of disease status in acute myelogenous leukemias.
    Cancer treatment reports, 1978, Volume: 62, Issue:1

    Topics: Acetylglucosamine; Antineoplastic Agents; Bone Marrow; Galactose; Guanosine Diphosphate Fucose; Hexosyltransferases; Humans; Leukemia, Myeloid, Acute; Remission, Spontaneous

1978
Indirubin derivatives as potent FLT3 inhibitors with anti-proliferative activity of acute myeloid leukemic cells.
    Bioorganic & medicinal chemistry letters, 2010, Mar-15, Volume: 20, Issue:6

    Topics: Antibiotics, Antineoplastic; Cell Line, Tumor; Cell Proliferation; Humans; Indoles; Leukemia, Myeloid, Acute

2010
Novel ROS-activated agents utilize a tethered amine to selectively target acute myeloid leukemia.
    Bioorganic & medicinal chemistry letters, 2013, May-15, Volume: 23, Issue:10

    Topics: Amines; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; DNA; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Leukemia, Myeloid, Acute; Molecular Structure; Reactive Oxygen Species; Structure-Activity Relationship

2013
Identification of N-(4-((1R,3S,5S)-3-Amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide (PIM447), a Potent and Selective Proviral Insertion Site of Moloney Murine Leukemia (PIM) 1, 2, and 3 Kinase Inhibitor in Clinical Tria
    Journal of medicinal chemistry, 2015, Nov-12, Volume: 58, Issue:21

    Topics: Amides; Animals; Cell Line, Tumor; Halogenation; Humans; Leukemia, Myeloid, Acute; Mice; Models, Molecular; Picolinic Acids; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-pim-1

2015
Discovery of 4-((7H-Pyrrolo[2,3-d]pyrimidin-4-yl)amino)-N-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-1H-pyrazole-3-carboxamide (FN-1501), an FLT3- and CDK-Kinase Inhibitor with Potentially High Efficiency against Acute Myelocytic Leukemia.
    Journal of medicinal chemistry, 2018, 02-22, Volume: 61, Issue:4

    Topics: Amides; Animals; Antineoplastic Agents; Cell Line, Tumor; Cyclin-Dependent Kinases; Drug Discovery; fms-Like Tyrosine Kinase 3; Heterografts; Humans; Leukemia, Myeloid, Acute; Mice; Neoplasms; Protein Kinase Inhibitors; Pyrazoles; Structure-Activity Relationship

2018
Acute myeloid leukemia with cup-like blasts and FLT3-ITD and NPM1 mutations mimics features of acute promyelocytic leukemia: a case of durable remission after sorafenib and low-dose cytarabine.
    Anti-cancer drugs, 2022, 01-01, Volume: 33, Issue:1

    Topics: Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; fms-Like Tyrosine Kinase 3; HLA-DR Antigens; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Nucleophosmin; Sorafenib

2022
Primary mesenchymal stromal cells in co-culture with leukaemic HL-60 cells are sensitised to cytarabine-induced genotoxicity, while leukaemic cells are protected.
    Mutagenesis, 2021, 11-29, Volume: 36, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Bone Marrow Cells; Cell Line, Tumor; Cells, Cultured; Coculture Techniques; Comet Assay; Cytarabine; Female; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Male; Mesenchymal Stem Cells; Micronucleus Tests; Middle Aged; Pilot Projects

2021
MTH1 Inhibitor TH1579 Induces Oxidative DNA Damage and Mitotic Arrest in Acute Myeloid Leukemia.
    Cancer research, 2021, 11-15, Volume: 81, Issue:22

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blast Crisis; Cell Proliferation; Cytarabine; DNA Repair Enzymes; Doxorubicin; Female; Gene Expression Regulation, Leukemic; Humans; Leukemia, Myeloid, Acute; Mice; Mice, Inbred NOD; Mice, SCID; Mitosis; Neoplastic Stem Cells; Phosphoric Monoester Hydrolases; Prognosis; Pyrimidines; Reactive Oxygen Species; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2021
Outcome of patients with relapsed or refractory acute myeloid leukemia treated with Mito-FLAG salvage chemotherapy.
    Journal of cancer research and clinical oncology, 2022, Volume: 148, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Prognosis; Remission Induction; Salvage Therapy; Treatment Outcome; Vidarabine

2022
Safety and feasibility of outpatient high-dose cytarabine and intermediate-dose cytarabine for consolidation therapy in acute myeloid leukemia.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2022, Volume: 28, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Consolidation Chemotherapy; Cytarabine; Feasibility Studies; Humans; Leukemia, Myeloid, Acute; Outpatients; Retrospective Studies

2022
A novel intensive conditioning regimen for allogeneic hematopoietic stem cell transplantation in the treatment of relapsed/refractory acute myeloid leukemia.
    Neoplasma, 2021, Volume: 68, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Prospective Studies; Transplantation Conditioning

2021
Combination of treosulfan, fludarabine and cytarabine as conditioning in patients with acute myeloid leukemia, myelodysplastic syndrome and myeloproliferative neoplasms.
    Journal of cancer research and clinical oncology, 2022, Volume: 148, Issue:10

    Topics: Busulfan; Cytarabine; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Middle Aged; Myelodysplastic Syndromes; Myeloproliferative Disorders; Recurrence; Retrospective Studies; Transplantation Conditioning; Vidarabine

2022
Validation of AML-score in Older Adults Receiving CPX-351 Intensive Induction Chemotherapy for Treatment of Secondary Acute Myeloid Leukemia.
    Clinical lymphoma, myeloma & leukemia, 2022, Volume: 22, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Retrospective Studies

2022
CD157 signaling promotes survival of acute myeloid leukemia cells and modulates sensitivity to cytarabine through regulation of anti-apoptotic Mcl-1.
    Scientific reports, 2021, 10-27, Volume: 11, Issue:1

    Topics: ADP-ribosyl Cyclase; Adult; Aged; Aged, 80 and over; Antigens, CD; Antimetabolites, Antineoplastic; Apoptosis; Cells, Cultured; Cytarabine; Drug Resistance, Neoplasm; Female; GPI-Linked Proteins; Humans; Leukemia, Myeloid, Acute; Male; MAP Kinase Signaling System; Middle Aged; Myeloid Cell Leukemia Sequence 1 Protein; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Pyrimidines; Thiophenes; THP-1 Cells

2021
CPX-351 induces remission in newly diagnosed pediatric secondary myeloid malignancies.
    Blood advances, 2022, 01-25, Volume: 6, Issue:2

    Topics: Adolescent; Aged; Child; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Neoplasms, Second Primary; Prospective Studies

2022
Cotargeting of Bcl-2 and Mcl-1 shows promising antileukemic activity against AML cells including those with acquired cytarabine resistance.
    Experimental hematology, 2022, Volume: 105

    Topics: Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Cytarabine; Drug Resistance, Neoplasm; Drug Synergism; Humans; Leukemia, Myeloid, Acute; Molecular Targeted Therapy; Myeloid Cell Leukemia Sequence 1 Protein; Proto-Oncogene Proteins c-bcl-2; Pyrimidines; Sulfonamides; Thiophenes

2022
Intermediate-dose cytarabine or standard-dose cytarabine plus single-dose anthracycline as post-remission therapy in older patients with acute myeloid leukemia: impact on health care resource consumption and outcomes.
    Blood cancer journal, 2021, 11-13, Volume: 11, Issue:11

    Topics: Aged; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Registries; Remission Induction

2021
Outcomes of pediatric acute myeloid leukemia treatment in Western Kenya.
    Cancer reports (Hoboken, N.J.), 2022, Volume: 5, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Doxorubicin; Etoposide; Fluconazole; Humans; Kenya; Leukemia, Myeloid, Acute; Retrospective Studies; Trimethoprim, Sulfamethoxazole Drug Combination

2022
A multivalent Ara-C-prodrug nanoconjugate achieves selective ablation of leukemic cells in an acute myeloid leukemia mouse model.
    Biomaterials, 2022, Volume: 280

    Topics: Animals; Antineoplastic Agents; Cytarabine; Humans; Leukemia, Myeloid, Acute; Mice; Nanoconjugates; Prodrugs

2022
Ultraviolet recall due to cytarabine chemotherapy for acute myeloid leukaemia.
    BMJ case reports, 2021, Nov-30, Volume: 14, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Idarubicin; Leukemia, Myeloid, Acute

2021
Coculture in vitro with endothelial cells induces cytarabine resistance of acute myeloid leukemia cells in a VEGF-A/VEGFR-2 signaling-independent manner.
    Biochemical and biophysical research communications, 2022, 01-08, Volume: 587

    Topics: Angiogenesis Inhibitors; Antimetabolites, Antineoplastic; Cell Cycle; Cell Line; Cell Movement; Coculture Techniques; Cytarabine; Drug Resistance, Neoplasm; Endothelial Cells; Gene Expression Regulation, Leukemic; Gene Knockout Techniques; HL-60 Cells; Humans; Indoles; Jurkat Cells; K562 Cells; Leukemia, Myeloid, Acute; Models, Biological; Neovascularization, Pathologic; Phosphorylation; Signal Transduction; U937 Cells; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2

2022
What to use to treat AML: the role of emerging therapies.
    Hematology. American Society of Hematology. Education Program, 2021, 12-10, Volume: 2021, Issue:1

    Topics: Aged; Aminopyridines; Aniline Compounds; Antineoplastic Agents; Cytarabine; Daunorubicin; Drug Approval; Drug Discovery; Glycine; Humans; Leukemia, Myeloid, Acute; Male; Neoplasm Recurrence, Local; Pyrazines; Pyridines; Triazines

2021
Low dose of homoharringtonine and cytarabine-based priming induction regimens for patients with
    Hematology (Amsterdam, Netherlands), 2021, Volume: 26, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Homoharringtonine; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Myelodysplastic Syndromes; Retrospective Studies; Survival Analysis; Treatment Outcome

2021
European LeukemiaNet 2017 risk stratification for acute myeloid leukemia: validation in a risk-adapted protocol.
    Blood advances, 2022, 02-22, Volume: 6, Issue:4

    Topics: Cytarabine; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Retrospective Studies; Risk Assessment

2022
Critical role of Lama4 for hematopoiesis regeneration and acute myeloid leukemia progression.
    Blood, 2022, 05-19, Volume: 139, Issue:20

    Topics: Animals; Cytarabine; Drug Resistance, Neoplasm; Hematopoiesis; Humans; Laminin; Leukemia, Myeloid, Acute; Mesenchymal Stem Cells; Mice; Mice, Knockout; Reactive Oxygen Species

2022
The "7+3" regimen in acute myeloid leukemia.
    Haematologica, 2022, 01-01, Volume: 107, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Leukemia, Myeloid, Acute

2022
Polygenic Ara-C Response Score Identifies Pediatric Patients With Acute Myeloid Leukemia in Need of Chemotherapy Augmentation.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2022, 03-01, Volume: 40, Issue:7

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Child; Child, Preschool; Cytarabine; Daunorubicin; Etoposide; Female; Follow-Up Studies; Gemtuzumab; Humans; Induction Chemotherapy; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Male; Polymorphism, Single Nucleotide; Prognosis; Survival Rate; Young Adult

2022
Beyond Survival: The US Food and Drug Administration Confirms Surrogate End Points for Patients With Newly Diagnosed Acute Myeloid Leukemia Treated With Intensive Chemotherapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2022, 03-10, Volume: 40, Issue:8

    Topics: Biomarkers; Cytarabine; Humans; Leukemia, Myeloid, Acute; Progression-Free Survival; United States; United States Food and Drug Administration

2022
Toward Personalization of Cytarabine Dosing in Acute Myeloid Leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2022, 03-01, Volume: 40, Issue:7

    Topics: Cytarabine; Humans; Leukemia, Myeloid, Acute; Remission Induction

2022
Novel inhibitor of hematopoietic cell kinase as a potential therapeutic agent for acute myeloid leukemia.
    Cancer immunology, immunotherapy : CII, 2022, Volume: 71, Issue:8

    Topics: Animals; Azacitidine; Cytarabine; Leukemia, Myeloid, Acute; Mice; Myelodysplastic Syndromes; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-hck

2022
Neutropenia in the First Cycle of Consolidation Chemotherapy with High-Dose Cytarabine Is Not Associated with the Incidence of Relapse in Adult Acute Myeloid Leukemia Patients in First Complete Remission.
    Acta haematologica, 2022, Volume: 145, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Consolidation Chemotherapy; Cytarabine; Humans; Incidence; Leukemia, Myeloid, Acute; Neutropenia; Recurrence; Remission Induction

2022
Curcumin sensitizes response to cytarabine in acute myeloid leukemia by regulating intestinal microbiota.
    Cancer chemotherapy and pharmacology, 2022, Volume: 89, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cholesterol; Curcumin; Cytarabine; Drug Resistance, Neoplasm; Drug Synergism; Gastrointestinal Microbiome; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Male; Metabolomics; Metagenomics; Mice; Xenograft Model Antitumor Assays

2022
Standard-Intensity Induction and Intermediate/High-Dose Cytarabine Consolidation Can Improve Survival for Elderly Patients with Newly Diagnosed Acute Myeloid Leukemia: A Retrospective Cohort Study.
    Clinical interventions in aging, 2022, Volume: 17

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Remission Induction; Retrospective Studies

2022
Clinical experience with venetoclax in patients with newly diagnosed, relapsed, or refractory acute myeloid leukemia.
    Journal of cancer research and clinical oncology, 2022, Volume: 148, Issue:11

    Topics: Adult; Aged; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Humans; Leukemia, Myeloid, Acute; Nuclear Proteins; Proto-Oncogene Proteins c-bcl-2; Retrospective Studies; Sulfonamides

2022
Retreatment with full-dose cytarabine in a patient with previous neurological toxicity.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2022, Volume: 28, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Remission Induction; Retreatment

2022
Validation of CRISPR targeting for proliferation and cytarabine resistance control genes in the acute myeloid leukemia cell line MOLM-13.
    BioTechniques, 2022, Volume: 72, Issue:3

    Topics: Cell Line; Cell Line, Tumor; Cell Proliferation; Clustered Regularly Interspaced Short Palindromic Repeats; Cytarabine; Humans; Leukemia, Myeloid, Acute

2022
Mitochondrial inhibitors circumvent adaptive resistance to venetoclax and cytarabine combination therapy in acute myeloid leukemia.
    Nature cancer, 2021, Volume: 2, Issue:11

    Topics: Azacitidine; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Humans; Leukemia, Myeloid, Acute; Sulfonamides

2021
Metformin sensitizes AML cells to chemotherapy through blocking mitochondrial transfer from stromal cells to AML cells.
    Cancer letters, 2022, 04-28, Volume: 532

    Topics: Animals; Cytarabine; Diabetes Mellitus, Type 2; Humans; Leukemia, Myeloid, Acute; Metformin; Mice; Mice, Nude; Mice, SCID; Mitochondria; Stromal Cells; Tumor Microenvironment

2022
Real-world treatment patterns and clinical outcomes in patients with AML unfit for first-line intensive chemotherapy
    Leukemia & lymphoma, 2022, Volume: 63, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Retrospective Studies; Treatment Outcome

2022
Activity of decitabine as maintenance therapy in core binding factor acute myeloid leukemia.
    American journal of hematology, 2022, Volume: 97, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Core Binding Factors; Cytarabine; Decitabine; Humans; Leukemia, Myeloid, Acute; Neoplasm, Residual; Prognosis

2022
Decitabine combined with minimally myelosuppressive therapy for induction of remission in pediatric high-risk acute myeloid leukemia with chromosome 5q deletion: a report of three cases.
    International journal of hematology, 2022, Volume: 116, Issue:1

    Topics: Abnormal Karyotype; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Chromosome Aberrations; Chromosome Deletion; Cytarabine; Decitabine; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Remission Induction

2022
The new mitochondrial uncoupler BAM15 induces ROS production for treatment of acute myeloid leukemia.
    Biochemical pharmacology, 2022, Volume: 198

    Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cytarabine; Diamines; Leukemia, Myeloid, Acute; Mice; Oxadiazoles; Pyrazines; Reactive Oxygen Species

2022
Chidamide and Decitabine in Combination with a HAG Priming Regimen for Acute Myeloid Leukemia with TP53 Mutation.
    Acta medica Okayama, 2022, Volume: 76, Issue:1

    Topics: Adult; Aged; Aminopyridines; Antimetabolites, Antineoplastic; Benzamides; Cytarabine; Decitabine; Female; Granulocyte Colony-Stimulating Factor; Homoharringtonine; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Remission Induction; Retrospective Studies; Treatment Outcome; Tumor Suppressor Protein p53

2022
Is acute myeloid leukaemia maintenance therapy necessary?
    The Lancet. Haematology, 2022, Volume: 9, Issue:3

    Topics: Cytarabine; Humans; Leukemia, Myeloid, Acute

2022
Venetoclax in combination with hypomethylating agents or low dose cytarabine for relapsed and refractory acute myeloid leukemia.
    Leukemia & lymphoma, 2022, Volume: 63, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Humans; Leukemia, Myeloid, Acute; Retrospective Studies; Sulfonamides

2022
The prognostic factors in acute myeloid leukaemia with double-mutated CCAAT/enhancer-binding protein alpha (CEBPAdm).
    British journal of haematology, 2022, Volume: 197, Issue:4

    Topics: CCAAT-Enhancer-Binding Protein-alpha; CCAAT-Enhancer-Binding Proteins; Cytarabine; Homoharringtonine; Humans; Leukemia, Myeloid, Acute; Mutation; Neoplasm Recurrence, Local; Prognosis; Receptors, Colony-Stimulating Factor; Retrospective Studies

2022
Adverse stem cell clones within a single patient's tumor predict clinical outcome in AML patients.
    Journal of hematology & oncology, 2022, 03-12, Volume: 15, Issue:1

    Topics: Clone Cells; Cytarabine; Drug Resistance, Neoplasm; Humans; Leukemia, Myeloid, Acute; Proteomics; Recurrence; Stem Cells

2022
Cytarabine-induced TNFα promotes the expansion and suppressive functions of myeloid-derived suppressor cells in acute myeloid leukaemia.
    Scandinavian journal of immunology, 2022, Volume: 95, Issue:6

    Topics: Cytarabine; Humans; Interleukin-6; Leukemia, Myeloid, Acute; Myeloid-Derived Suppressor Cells; Tumor Microenvironment; Tumor Necrosis Factor-alpha

2022
Healthcare resource utilization trends in patients with acute myeloid leukemia ineligible for intensive chemotherapy receiving first-line systemic treatment or best supportive care: A multicenter international study.
    European journal of haematology, 2022, Volume: 109, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Leukemia, Myeloid, Acute; Patient Acceptance of Health Care; Retrospective Studies

2022
Cost-effectiveness of liposomal cytarabine/daunorubicin in patients with newly diagnosed acute myeloid leukemia.
    Blood, 2022, 03-17, Volume: 139, Issue:11

    Topics: Anthracyclines; Cost-Benefit Analysis; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute

2022
Adenosine Monophosphate Activated Protein Kinase (AMPK) enhances chemotherapy response in Acute Myeloid Leukemia (AML).
    Cancer letters, 2022, 06-01, Volume: 535

    Topics: Adenosine Monophosphate; AMP-Activated Protein Kinases; Apoptosis; Cytarabine; Humans; Leukemia, Myeloid, Acute

2022
IL-6 promotes chemoresistance via upregulating CD36 mediated fatty acids uptake in acute myeloid leukemia.
    Experimental cell research, 2022, 06-01, Volume: 415, Issue:1

    Topics: Animals; Cytarabine; Drug Resistance, Neoplasm; Fatty Acids; Humans; Interleukin-6; Leukemia, Myeloid, Acute; Mice; Mice, Knockout; Receptors, Interleukin-6

2022
Real-world treatment patterns and clinical outcomes in patients with AML in Japan who were ineligible for first-line intensive chemotherapy.
    International journal of hematology, 2022, Volume: 116, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Humans; Japan; Leukemia, Myeloid, Acute; Retrospective Studies; Treatment Outcome

2022
[Influence of Serum TGF-β1 and EGFR Levels on the Therapeutic Effect of High-Dose AraC in Patients with Acute Myeloid Leukemia Based on the Decision Curve].
    Zhongguo shi yan xue ye xue za zhi, 2022, Volume: 30, Issue:2

    Topics: Cytarabine; ErbB Receptors; Humans; Leukemia, Myeloid, Acute; Remission Induction; Transforming Growth Factor beta1

2022
[Influence of Serum TGF-β1 and EGFR Levels on the Therapeutic Effect of High-Dose AraC in Patients with Acute Myeloid Leukemia Based on the Decision Curve].
    Zhongguo shi yan xue ye xue za zhi, 2022, Volume: 30, Issue:2

    Topics: Cytarabine; ErbB Receptors; Humans; Leukemia, Myeloid, Acute; Remission Induction; Transforming Growth Factor beta1

2022
Effect of Chemotherapy Cytarabine and Acute Myeloid Leukemia on the Development of Spermatogenesis at the Adult Age of Immature Treated Mice.
    International journal of molecular sciences, 2022, Apr-04, Volume: 23, Issue:7

    Topics: Adult; Animals; Child; Cytarabine; Glial Cell Line-Derived Neurotrophic Factor; Humans; Interleukin-6; Leukemia, Myeloid, Acute; Male; Mice; RNA; Seminiferous Tubules; Spermatogenesis; Spermatogonia; Testis; Tumor Microenvironment

2022
Urgent cytoreduction for newly diagnosed acute myeloid leukemia patients allows acquisition of pretreatment genomic data and enrollment on investigational clinical trials.
    American journal of hematology, 2022, Volume: 97, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Cytoreduction Surgical Procedures; Genomics; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Middle Aged; Prospective Studies; Treatment Outcome; Young Adult

2022
The favorable prognostic value of the loss of sex chromosomes in patients with t(8;21) acute myeloid leukemia: an exploratory study.
    Hematology (Amsterdam, Netherlands), 2022, Volume: 27, Issue:1

    Topics: Cytarabine; Disease-Free Survival; Humans; Leukemia, Myeloid, Acute; Male; Prognosis; Retrospective Studies; Sex Chromosomes

2022
Single-dose (4.5 mg/m
    British journal of haematology, 2022, Volume: 198, Issue:2

    Topics: Adult; Aminoglycosides; Anthracyclines; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Prospective Studies; Vidarabine

2022
Transplant outcomes after CPX-351 vs 7 + 3 in older adults with newly diagnosed high-risk and/or secondary AML.
    Blood advances, 2022, 09-13, Volume: 6, Issue:17

    Topics: Aged; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Neoplasms, Second Primary

2022
Artesunate improves venetoclax plus cytarabine AML cell targeting by regulating the Noxa/Bim/Mcl-1/p-Chk1 axis.
    Cell death & disease, 2022, 04-20, Volume: 13, Issue:4

    Topics: Aged; Animals; Apoptosis; Apoptosis Regulatory Proteins; Artesunate; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Checkpoint Kinase 1; Cytarabine; Humans; Leukemia, Myeloid, Acute; Mice; Myeloid Cell Leukemia Sequence 1 Protein; Proto-Oncogene Proteins c-bcl-2; Sulfonamides

2022
Venetoclax combinations delay the time to deterioration of HRQoL in unfit patients with acute myeloid leukemia.
    Blood cancer journal, 2022, 04-20, Volume: 12, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Fatigue; Humans; Leukemia, Myeloid, Acute; Quality of Life; Sulfonamides

2022
Detection of residual and chemoresistant leukemic cells in an immune-competent mouse model of acute myeloid leukemia: Potential for unravelling their interactions with immunity.
    PloS one, 2022, Volume: 17, Issue:4

    Topics: Animals; Cytarabine; Disease Models, Animal; Disease Progression; Humans; Leukemia, Myeloid, Acute; Mice; Neoplasm, Residual

2022
Real-world effectiveness of CPX-351 vs venetoclax and azacitidine in acute myeloid leukemia.
    Blood advances, 2022, 07-12, Volume: 6, Issue:13

    Topics: Aged; Azacitidine; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Prospective Studies; Quality of Life; Retrospective Studies; Sulfonamides

2022
Autologous hematopoietic stem cell transplantation followed by interleukin-2 for adult acute myeloid leukemia patients with favorable or intermediate risk after complete remission.
    Annals of hematology, 2022, Volume: 101, Issue:8

    Topics: Adult; Cytarabine; Hematopoietic Stem Cell Transplantation; Humans; Interleukin-2; Leukemia, Myeloid, Acute; Remission Induction; Retrospective Studies; Transplantation, Autologous

2022
Venetoclax combined with FLAG-IDA induction and consolidation in newly diagnosed acute myeloid leukemia.
    American journal of hematology, 2022, Volume: 97, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Middle Aged; Prospective Studies; Remission Induction; Sulfonamides; Vidarabine; Young Adult

2022
Involvement of ORAI1/SOCE in Human AML Cell Lines and Primary Cells According to ABCB1 Activity, LSC Compartment and Potential Resistance to Ara-C Exposure.
    International journal of molecular sciences, 2022, 05-16, Volume: 23, Issue:10

    Topics: ATP Binding Cassette Transporter, Subfamily B; Calcium; Calcium Signaling; Cell Line; Cytarabine; Humans; Leukemia, Myeloid, Acute; ORAI1 Protein; Stromal Interaction Molecule 1

2022
[Comparison of the efficacy of IA and HAD induction regimens in the treatment of patients with newly diagnosed acute myeloid leukemia: a single-center study].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2022, May-14, Volume: 43, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Homoharringtonine; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Nuclear Proteins; Prognosis; Remission Induction; Retrospective Studies; Young Adult

2022
[The efficacy and safety of CLAG-M/I regimen for relapsed or refractory acute myeloid leukemia in children].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2022, 04-14, Volume: 43, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Recurrence; Treatment Outcome

2022
[Establishment of Drug-Resistant Cell Lines of Acute Myeloid Leukemia and Correlation of Sirt1 and PGC-1α Expression Levels with Drug Resistance].
    Zhongguo shi yan xue ye xue za zhi, 2022, Volume: 30, Issue:3

    Topics: Cell Line; Cytarabine; Drug Resistance; Humans; Leukemia, Myeloid, Acute; RNA, Messenger; Sirtuin 1

2022
Adjunction of a fish oil emulsion to cytarabine and daunorubicin induction chemotherapy in high-risk AML.
    Scientific reports, 2022, 06-13, Volume: 12, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Docosahexaenoic Acids; Eicosapentaenoic Acid; Emulsions; Feasibility Studies; Fish Oils; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; NF-E2-Related Factor 2

2022
Granulocytic sarcoma of cervix: A rare case report.
    Medicine, 2022, Jun-17, Volume: 101, Issue:24

    Topics: Cervix Uteri; Cytarabine; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Middle Aged; Sarcoma, Myeloid

2022
Venetoclax in combination with FLAG-IDA-based protocol for patients with acute myeloid leukemia: a real-world analysis.
    Annals of hematology, 2022, Volume: 101, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Humans; Leukemia, Myeloid, Acute; Middle Aged; Multicenter Studies as Topic; Retrospective Studies; Sulfonamides

2022
Daunorubicin-60 versus daunorubicin-90 versus idarubicin-12 for induction chemotherapy in acute myeloid leukemia: a retrospective analysis of the Mayo Clinic experience.
    Haematologica, 2022, 10-01, Volume: 107, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Remission Induction; Retrospective Studies

2022
A multiparametric niche-like drug screening platform in acute myeloid leukemia.
    Blood cancer journal, 2022, 06-24, Volume: 12, Issue:6

    Topics: Anthracyclines; Cytarabine; Drug Evaluation, Preclinical; Humans; Leukemia, Myeloid, Acute; Mesenchymal Stem Cells; Neoplastic Stem Cells

2022
Outcomes and hospitalization patterns of patients with acute myelogenous leukemia treated with frontline CPX-351 or HMA/venetoclax.
    Leukemia research, 2022, Volume: 119

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Daunorubicin; Hospitalization; Humans; Leukemia, Myeloid, Acute; Sulfonamides

2022
CPX-351 Yields Similar Response and Survival Outcome in Younger and Older Patients With Secondary Acute Myeloid Leukemia.
    Clinical lymphoma, myeloma & leukemia, 2022, Volume: 22, Issue:10

    Topics: Adolescent; Adult; Aged; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Middle Aged; Neoplasms, Second Primary; Retrospective Studies

2022
Re-induction versus salvage for D14-resiudal acute myeloid leukemia: A retrospective multi-center study.
    Leukemia research, 2022, Volume: 119

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Prognosis; Remission Induction; Retrospective Studies; Salvage Therapy; Treatment Outcome

2022
Pooled shRNA Library Screening to Identify Factors that Modulate a Drug Resistance Phenotype.
    Journal of visualized experiments : JoVE, 2022, 06-17, Issue:184

    Topics: Cytarabine; Drug Resistance; Humans; Leukemia, Myeloid, Acute; Phenotype; RNA, Small Interfering

2022
Retrospective analysis of three induction chemotherapy regimens in acute myeloid leukemia including CPX-351, cytarabine/daunorubicin with and without the addition of cladribine.
    Leukemia & lymphoma, 2022, Volume: 63, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cytarabine; Daunorubicin; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Retrospective Studies

2022
Cytarabine-induced differentiation of AML cells depends on Chk1 activation and shares the mechanism with inhibitors of DHODH and pyrimidine synthesis.
    Scientific reports, 2022, 07-05, Volume: 12, Issue:1

    Topics: Cell Differentiation; Checkpoint Kinase 1; Cytarabine; Dihydroorotate Dehydrogenase; Enzyme Inhibitors; Humans; Leukemia, Myeloid, Acute; Pyrimidines

2022
Stabilization of SAMHD1 by NONO is crucial for Ara-C resistance in AML.
    Cell death & disease, 2022, 07-08, Volume: 13, Issue:7

    Topics: Cytarabine; DNA-Binding Proteins; Humans; Leukemia, Myeloid, Acute; RNA-Binding Proteins; SAM Domain and HD Domain-Containing Protein 1

2022
Nrf2 overexpression increases the resistance of acute myeloid leukemia to cytarabine by inhibiting replication factor C4.
    Cancer gene therapy, 2022, Volume: 29, Issue:11

    Topics: Cell Line, Tumor; Cytarabine; Drug Resistance, Neoplasm; Humans; Leukemia, Myeloid, Acute; NF-E2-Related Factor 2; NF-kappa B

2022
Exosomes from bone marrow mesenchymal stem cells decrease chemosensitivity of acute myeloid leukemia cells via delivering miR-10a.
    Biochemical and biophysical research communications, 2022, 09-24, Volume: 622

    Topics: Bone Marrow Cells; Cell Cycle Proteins; Cell Proliferation; Cytarabine; Exosomes; Humans; Leukemia, Myeloid, Acute; Mesenchymal Stem Cells; MicroRNAs; Repressor Proteins; Tumor Microenvironment

2022
Optimal dosing of cytarabine in childhood acute myeloid leukemia: do we have the answer yet?
    Leukemia & lymphoma, 2022, Volume: 63, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Humans; Leukemia, Myeloid, Acute; Myeloproliferative Disorders

2022
Favorable Outcome with Conditioning Regimen of Flu/Bu4/Mel in Acute Myeloid Leukemia Patients in Remission Undergoing Cord Blood Transplantation.
    Transplantation and cellular therapy, 2022, Volume: 28, Issue:11

    Topics: Cord Blood Stem Cell Transplantation; Cyclophosphamide; Cytarabine; Humans; Leukemia, Myeloid, Acute; Recurrence; Transplantation Conditioning; Transplantation, Homologous

2022
Real-world analysis of tumor lysis syndrome in patients started on venetoclax combination for acute myeloid leukemia.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2023, Volume: 29, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Leukemia, Myeloid, Acute; Retrospective Studies; Tumor Lysis Syndrome

2023
Isocitrate dehydrogenase 2 inhibitor enasidenib synergizes daunorubicin cytotoxicity by targeting aldo-keto reductase 1C3 and ATP-binding cassette transporters.
    Archives of toxicology, 2022, Volume: 96, Issue:12

    Topics: Adenosine Triphosphate; Anthracyclines; Antibiotics, Antineoplastic; ATP-Binding Cassette Transporters; Cytarabine; Daunorubicin; Humans; Isocitrate Dehydrogenase; Leukemia, Myeloid, Acute

2022
Pneumocystis jirovecii pneumonia [PJP]: An unrecognized concern in AML patients on Venetoclax.
    Leukemia research, 2022, Volume: 121

    Topics: Aged; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Humans; Idarubicin; Leukemia, Myeloid, Acute; Pneumocystis carinii; Pneumonia, Pneumocystis; Proto-Oncogene Proteins c-bcl-2; Sulfonamides; Trimethoprim, Sulfamethoxazole Drug Combination

2022
5'-nucleotidase, cytosolic II genotype, and clinical outcome in patients with acute myeloid leukemia with intermediate-risk cytogenetics.
    European journal of haematology, 2022, Volume: 109, Issue:6

    Topics: 5'-Nucleotidase; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Cytidine Deaminase; Cytogenetic Analysis; Genotype; Humans; Leukemia, Myeloid, Acute; Middle Aged; Prognosis; Remission Induction

2022
Ceramide nanoliposomes augment the efficacy of venetoclax and cytarabine in models of acute myeloid leukemia.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2022, Volume: 36, Issue:10

    Topics: Animals; Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Ceramides; Cytarabine; Leukemia, Myeloid, Acute; Sulfonamides

2022
Impact on Outcome of Minimal Residual Disease after Hematopoietic Stem Cell Transplantation with Fludarabine, Amsacrine, and Cytosine Arabinoside-Busulfan Conditioning: A Retrospective Monocentric Study.
    Transplantation and cellular therapy, 2023, Volume: 29, Issue:1

    Topics: Amsacrine; Busulfan; Cytarabine; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Neoplasm, Residual; Recurrence; Retrospective Studies

2023
Long-term follow-up of VIALE-C in patients with untreated AML ineligible for intensive chemotherapy.
    Blood, 2022, 12-22, Volume: 140, Issue:25

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute

2022
Treatment of myeloid neoplasia with doxorubicin and cytarabine in 11 dogs.
    Veterinary and comparative oncology, 2023, Volume: 21, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dog Diseases; Dogs; Doxorubicin; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes

2023
Subclones of bone marrow CD34
    Cancer, 2022, 11-15, Volume: 128, Issue:22

    Topics: Anthracyclines; Antigens, CD34; Bone Marrow; Cytarabine; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute

2022
[Clinical Efficacy and Survival Analysis of Adult Patients with Acute Myeloid Leukemia after Microtransplantation].
    Zhongguo shi yan xue ye xue za zhi, 2022, Volume: 30, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Decitabine; Female; Graft vs Host Disease; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Retrospective Studies; Survival Analysis; Treatment Outcome

2022
Co-targeting of HDAC, PI3K, and Bcl-2 results in metabolic and transcriptional reprogramming and decreased mitochondrial function in acute myeloid leukemia.
    Biochemical pharmacology, 2022, Volume: 205

    Topics: Animals; Apoptosis; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Cytarabine; Leukemia, Myeloid, Acute; Mice; Mitochondria; Phosphatidylinositol 3-Kinases

2022
Utility of therapeutic drug monitoring of venetoclax in acute myeloid leukemia.
    Medical oncology (Northwood, London, England), 2022, Oct-12, Volume: 39, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Cytochrome P-450 CYP3A Inhibitors; Drug Monitoring; Humans; Itraconazole; Leukemia, Myeloid, Acute; Sulfonamides

2022
Pruritic papules after induction chemotherapy with daunorubicin and cytarabine.
    Dermatology online journal, 2022, Jun-15, Volume: 28, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Daunorubicin; Exanthema; Female; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Pruritus; Triamcinolone

2022
Isolated myeloid sarcoma with pericardial and pleural effusions as first manifestation: A case report.
    Medicine, 2022, Oct-21, Volume: 101, Issue:42

    Topics: Adult; Cytarabine; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Pleural Effusion; Sarcoma, Myeloid

2022
Real-World Treatment Patterns and Clinical Outcomes in Canadian Patients with AML Unfit for First-Line Intensive Chemotherapy.
    Current oncology (Toronto, Ont.), 2022, 09-22, Volume: 29, Issue:10

    Topics: Aged; Canada; Cytarabine; Humans; Leukemia, Myeloid, Acute; Prognosis; Retrospective Studies

2022
Exosomal miR92a Promotes Cytarabine Resistance in Myelodysplastic Syndromes by Activating Wnt/β-catenin Signal Pathway.
    Biomolecules, 2022, 10-09, Volume: 12, Issue:10

    Topics: beta Catenin; Cytarabine; Humans; Leukemia, Myeloid, Acute; MicroRNAs; Myelodysplastic Syndromes; Wnt Signaling Pathway

2022
[Acute myeloid leukemia harboring NUP98::DDX10].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2022, Volume: 63, Issue:10

    Topics: Cytarabine; DEAD-box RNA Helicases; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Middle Aged; Neoplasm, Residual; Nuclear Pore Complex Proteins; Prognosis; Recurrence

2022
Transcriptomics of acute myeloid leukaemia core bone marrow biopsies reveals distinct therapy response-specific osteo-mesenchymal profiles.
    British journal of haematology, 2023, Volume: 200, Issue:6

    Topics: Anthracyclines; Biopsy; Bone Marrow; Bone Marrow Cells; Cytarabine; Humans; Leukemia, Myeloid, Acute; Transcriptome; Tumor Microenvironment

2023
Early changes in gene expression profiles in AML patients during induction chemotherapy.
    BMC genomics, 2022, Nov-14, Volume: 23, Issue:1

    Topics: Cytarabine; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; NF-kappa B; Pilot Projects; Transcriptome

2022
Targeting cell cycle and apoptosis to overcome chemotherapy resistance in acute myeloid leukemia.
    Leukemia, 2023, Volume: 37, Issue:1

    Topics: Apoptosis; Cell Cycle; Cell Cycle Checkpoints; Cell Line, Tumor; Cytarabine; Humans; Leukemia, Myeloid, Acute

2023
A retrospective study of cladribine and low-dose cytarabine-based regimens for the treatment of chronic myelomonocytic leukemia and secondary acute myeloid leukemia.
    Cancer, 2023, 02-15, Volume: 129, Issue:4

    Topics: Cladribine; Cytarabine; Humans; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Prospective Studies; Retrospective Studies

2023
    Zhongguo shi yan xue ye xue za zhi, 2022, Volume: 30, Issue:6

    Topics: Apoptosis; Artesunate; Caspase 3; Caspase 9; Cell Line; Cytarabine; Daunorubicin; Humans; Leukemia; Leukemia, Myeloid, Acute; Mutation; Retrospective Studies

2022
EIF4A inhibition targets bioenergetic homeostasis in AML MOLM-14 cells in vitro and in vivo and synergizes with cytarabine and venetoclax.
    Journal of experimental & clinical cancer research : CR, 2022, Dec-09, Volume: 41, Issue:1

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cytarabine; Eukaryotic Initiation Factor-4A; Humans; Leukemia, Myeloid, Acute; Proto-Oncogene Proteins c-bcl-2

2022
Retrospective, real-life study of venetoclax plus azacitidine or low-dose cytarabine in French patients with acute myeloid leukemia ineligible for intensive chemotherapy.
    Cancer medicine, 2023, Volume: 12, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Humans; Leukemia, Myeloid, Acute; Retrospective Studies

2023
Optimizing outcomes in secondary AML.
    Hematology. American Society of Hematology. Education Program, 2022, 12-09, Volume: 2022, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Neoplasms, Second Primary

2022
Safety and efficacy of CPX-351 in younger patients (<60 years old) with secondary acute myeloid leukemia.
    Blood, 2023, 03-23, Volume: 141, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Middle Aged; Neoplasms, Second Primary

2023
Infectious complications after intensive chemotherapy with CLAG-M versus 7+3 for AML and other high-grade myeloid neoplasms.
    Leukemia, 2023, Volume: 37, Issue:2

    Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Bacterial Infections; Cladribine; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Infections; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mitoxantrone; Respiratory Tract Infections; Sepsis

2023
Nuclear factor Nrf2 promotes glycosidase OGG1 expression by activating the AKT pathway to enhance leukemia cell resistance to cytarabine.
    The Journal of biological chemistry, 2023, Volume: 299, Issue:1

    Topics: Apoptosis; Cell Nucleus; Cytarabine; DNA Glycosylases; Drug Resistance, Neoplasm; Humans; Leukemia, Myeloid, Acute; NF-E2-Related Factor 2; Proto-Oncogene Proteins c-akt

2023
Common kinase mutations do not impact optimal molecular responses in core binding factor acute myeloid leukemia treated with fludarabine, cytarabine, and G-CSF based regimens.
    American journal of hematology, 2023, Volume: 98, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Core Binding Factors; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Mutation; Vidarabine

2023
Re-induction therapy in patients with acute myeloid leukemia not in complete remission after the first course of treatment.
    Annals of hematology, 2023, Volume: 102, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Prognosis; Remission Induction; Retrospective Studies

2023
Cost-effectiveness analysis of gemtuzumab ozogamicin for the treatment of de novo CD33-positive Acute Myeloid Leukaemia (AML) in Italy.
    BMC health services research, 2023, Jan-16, Volume: 23, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cost-Effectiveness Analysis; Cytarabine; Daunorubicin; Gemtuzumab; Humans; Italy; Leukemia, Myeloid, Acute; Sialic Acid Binding Ig-like Lectin 3; State Medicine; Treatment Outcome

2023
Exposure to cytarabine causes side effects on adult development and physiology and induces intestinal damage via apoptosis in Drosophila.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 159

    Topics: Animals; Apoptosis; Cytarabine; Drosophila; Drosophila melanogaster; Drug-Related Side Effects and Adverse Reactions; Leukemia, Myeloid, Acute

2023
SAMHD1 single nucleotide polymorphisms impact outcome in children with newly diagnosed acute myeloid leukemia.
    Blood advances, 2023, 06-13, Volume: 7, Issue:11

    Topics: Arabinofuranosylcytosine Triphosphate; Child; Cytarabine; Humans; Leukemia, Myeloid, Acute; Polymorphism, Single Nucleotide; SAM Domain and HD Domain-Containing Protein 1

2023
Different treatment strategies versus a common standard arm (CSA) in patients with newly diagnosed AML over the age of 60 years: a randomized German inter-group study.
    Annals of hematology, 2023, Volume: 102, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Humans; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Prognosis; Remission Induction

2023
Quantitative Profiling of Alpha-Subunit of IL-3 Receptor on Single Acute Myeloid Leukemia Cells by Super-Resolution Imaging.
    Asian Pacific journal of cancer prevention : APJCP, 2023, Jan-01, Volume: 24, Issue:1

    Topics: Cell Line, Tumor; Cytarabine; Flow Cytometry; Humans; Interleukin-3 Receptor alpha Subunit; Leukemia, Myeloid, Acute; Receptors, Interleukin-3

2023
[A comparative clinical study of modified IA "3+4" regimen and intermediate-dose cytarabine regimen in the consolidation treatment of low-risk acute myeloid leukemia].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2022, 07-14, Volume: 43, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Idarubicin; Leukemia, Myeloid, Acute; Remission Induction

2022
[Analysis of the efficacy of azacitidine combined with homoharringtonine and cytarabine in induction and salvage therapy of acute myeloid leukemia].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2022, 09-14, Volume: 43, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Homoharringtonine; Humans; Leukemia, Myeloid, Acute; Remission Induction; Salvage Therapy; Treatment Outcome

2022
Amsacrine-based induction therapy in AML patients with cardiac comorbidities: a retrospective single-center analysis.
    Annals of hematology, 2023, Volume: 102, Issue:4

    Topics: Amsacrine; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Heart Diseases; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Remission Induction; Retrospective Studies

2023
Synergistic activity and mechanism of cytarabine and MCL-1 inhibitor AZD5991 against acute myeloid leukemia.
    Neoplasma, 2023, Volume: 70, Issue:2

    Topics: Cytarabine; Humans; Leukemia, Myeloid, Acute; Macrocyclic Compounds; Myeloid Cell Leukemia Sequence 1 Protein

2023
Venetoclax plus '2 + 5' modified intensive chemotherapy with daunorubicin and cytarabine in fit elderly patients with untreated de novo acute myeloid leukaemia: a single-centre retrospective analysis.
    British journal of haematology, 2023, Volume: 201, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Remission Induction; Retrospective Studies

2023
Chemotherapeutic drugs elicit stemness and metabolic alteration to mediate acquired drug-resistant phenotype in acute myeloid leukemia cell lines.
    Leukemia research, 2023, Volume: 128

    Topics: Antineoplastic Agents; Arsenic Trioxide; Cell Line, Tumor; Cytarabine; Humans; Leukemia, Myeloid, Acute; Phenotype

2023
Cytarabine-induced destabilization of MCL1 mRNA and protein triggers apoptosis in leukemia cells.
    Biochemical pharmacology, 2023, Volume: 211

    Topics: Antineoplastic Agents; Apoptosis; Cytarabine; Humans; Leukemia, Myeloid, Acute; Myeloid Cell Leukemia Sequence 1 Protein; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-akt; RNA, Messenger; U937 Cells

2023
Clinical characteristics and outcomes of children with newly diagnosed acute myeloid leukemia and hyperleukocytosis managed with different cytoreductive methods.
    Cancer, 2023, 06-15, Volume: 129, Issue:12

    Topics: Child; Cytarabine; Cytoreduction Surgical Procedures; Humans; Leukapheresis; Leukemia, Myeloid, Acute; Leukocyte Count; Leukocytosis

2023
Impact of FLT3-ITD location on cytarabine sensitivity in AML: a network-based approach.
    Leukemia, 2023, Volume: 37, Issue:5

    Topics: Cell Line, Tumor; Cytarabine; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Mutation

2023
Causal linkage of presence of mutant NPM1 to efficacy of novel therapeutic agents against AML cells with mutant NPM1.
    Leukemia, 2023, Volume: 37, Issue:6

    Topics: Aged; Cytarabine; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Mutation; Neoplasm Recurrence, Local; Nuclear Proteins; Nucleophosmin; Panobinostat

2023
Long term follow-up of refractory/relapsed acute myeloid leukemia patients treated with the FLAG-Ida regimen as bridge therapy to allotransplantation: 10-year results from a single centre experience.
    Leukemia research, 2023, Volume: 129

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bridge Therapy; Cytarabine; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Recurrence; Vidarabine

2023
Bewersdorf JP, Patel KK, Goshua G, et al. Cost-effectiveness of liposomal cytarabine/daunorubicin in patients with newly diagnosed acute myeloid leukemia. Blood. 2022;139(11):1766-1770.
    Blood, 2023, 04-06, Volume: 141, Issue:14

    Topics: Anthracyclines; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cost-Benefit Analysis; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute

2023
Expression of TFRC helps to improve the antineoplastic effect of Ara-C on AML cells through a targeted delivery carrier.
    Journal of nanobiotechnology, 2023, Apr-11, Volume: 21, Issue:1

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Cytarabine; Leukemia, Myeloid, Acute; Mice; Receptors, Transferrin

2023
Mannose metabolism inhibition sensitizes acute myeloid leukaemia cells to therapy by driving ferroptotic cell death.
    Nature communications, 2023, 04-14, Volume: 14, Issue:1

    Topics: Apoptosis; Cell Death; Cell Line, Tumor; Cytarabine; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Mannose

2023
Efficacy and safety of FLAG-IDA as front-line therapy in de novo paediatric acute myeloid leukaemia population.
    British journal of haematology, 2023, Volume: 202, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Vidarabine

2023
CAG (cytarabine, aclarubicin and granulocyte colony-stimulating factor) regimen for core binding factor acute myeloid leukaemia with measurable residual disease.
    Annals of hematology, 2023, Volume: 102, Issue:7

    Topics: Aclarubicin; Antineoplastic Combined Chemotherapy Protocols; Core Binding Factors; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Neoplasm Recurrence, Local; Neutropenia; Retrospective Studies; Treatment Outcome

2023
Older Adults With Newly Diagnosed AML: Hot Topics for the Practicing Clinician.
    American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting, 2023, Volume: 43

    Topics: Aged; Anthracyclines; Cytarabine; Humans; Leukemia, Myeloid, Acute

2023
Efficacy and toxicity of CLAG combined with pegylated liposomal doxorubicin in the treatment of refractory or relapsed acute myeloid leukemia.
    Cancer medicine, 2023, Volume: 12, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Prognosis; Retrospective Studies

2023
Outcomes with high dose cytarabine and mitoxantrone induction for adults with mixed phenotype acute leukemia.
    Leukemia research, 2023, Volume: 130

    Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Phenotype; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies

2023
Obesity in adult acute myeloid leukemia is not associated with inferior response or survival even when dose capping anthracyclines: An ECOG-ACRIN analysis.
    Cancer, 2023, 08-15, Volume: 129, Issue:16

    Topics: Aged; Anthracyclines; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Middle Aged; Obesity; Prospective Studies; Randomized Controlled Trials as Topic; Remission Induction

2023
Outcomes of adult patients with type 1 primary refractory acute myeloid leukemia: a single center experience.
    Hematology (Amsterdam, Netherlands), 2023, Volume: 28, Issue:1

    Topics: Adult; Cytarabine; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Remission Induction; Retrospective Studies

2023
Treatment of acute myeloid leukaemia in older patients - scope of intensive therapy? - A retrospective analysis.
    Hematology (Amsterdam, Netherlands), 2023, Volume: 28, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Prospective Studies; Retrospective Studies; Treatment Outcome

2023
Clinical outcomes after CPX-351 in patients with high-risk acute myeloid leukemia: A comparison with a matched cohort from the Spanish PETHEMA registry.
    Cancer medicine, 2023, Volume: 12, Issue:14

    Topics: Aged; Cytarabine; Humans; Leukemia, Myeloid, Acute; Remission Induction; Retrospective Studies

2023
Outcome and prognostic factors of CBF pediatric AML patients with t(8;21) differ from patients with inv(16).
    BMC cancer, 2023, May-25, Volume: 23, Issue:1

    Topics: Child; Cytarabine; Disease-Free Survival; Humans; Leukemia, Myeloid, Acute; Prognosis; Recurrence; Remission Induction

2023
Glutamate dehydrogenase 1: A novel metabolic target in inhibiting acute myeloid leukaemia progression.
    British journal of haematology, 2023, Volume: 202, Issue:3

    Topics: Animals; Cystine; Cytarabine; Glutamate Dehydrogenase; Glutamine; Glutathione; Leukemia, Myeloid, Acute; Mice

2023
CPX-351 for higher risk myelodysplastic syndrome: cytarabine and daunorubicin in disguise?
    The Lancet. Haematology, 2023, Volume: 10, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes

2023
Smart and Generalizable Cytarabine Derivative-Triggered Nanoparticles for Synergistic Therapy of Relapsed/Refractory Acute Myeloid Leukemia.
    ACS applied materials & interfaces, 2023, Jun-14, Volume: 15, Issue:23

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Leukemia, Myeloid, Acute; Mice; Sulfonamides

2023
Cellular Composition and 5hmC Signature Predict the Treatment Response of AML Patients to Azacitidine Combined with Chemotherapy.
    Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023, Volume: 10, Issue:23

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Clinical Trials, Phase I as Topic; Cytarabine; Humans; Leukemia, Myeloid, Acute

2023
Chloroquine enhances the efficacy of chemotherapy drugs against acute myeloid leukemia by inactivating the autophagy pathway.
    Acta pharmacologica Sinica, 2023, Volume: 44, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Autophagy; Chloroquine; Cytarabine; Daunorubicin; Humans; Idarubicin; Leukemia, Myeloid, Acute

2023
Uy GL, Newell LF, Lin TL, et al. Transplant outcomes after CPX-351 vs 7 + 3 in older adults with newly diagnosed high-risk and/or secondary AML. Blood Adv. 2022;6(17):4989-4993.
    Blood advances, 2023, Jun-27, Volume: 7, Issue:12

    Topics: Aged; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Transplants

2023
Real-world effectiveness of intensive chemotherapy with 7&3 versus venetoclax and hypomethylating agent in acute myeloid leukemia.
    American journal of hematology, 2023, Volume: 98, Issue:8

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Humans; Leukemia, Myeloid, Acute; Middle Aged; Retrospective Studies

2023
Efficacy and toxicity of midostaurin with idarubicin and cytarabine induction in FLT3-mutated acute myeloid leukemia.
    Haematologica, 2023, Dec-01, Volume: 108, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; fms-Like Tyrosine Kinase 3; Humans; Idarubicin; Leukemia, Myeloid, Acute; Mutation; Remission Induction; Staurosporine

2023
Intensified conditioning regimen with fludarabine combined with post-transplantation cyclophosphamide for haploidentical allogeneic hematopoietic stem cell transplantation in children with high-risk acute leukemia.
    Hematology (Amsterdam, Netherlands), 2023, Volume: 28, Issue:1

    Topics: Acute Disease; Adult; Antilymphocyte Serum; Busulfan; Child; Cyclophosphamide; Cytarabine; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Recurrence; Retrospective Studies; Transplantation Conditioning

2023
Treatment outcomes of pediatric acute myeloid leukemia in Western Kenya before and after the implementation of the SIOP PODC treatment guideline.
    Cancer reports (Hoboken, N.J.), 2023, Volume: 6, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Etoposide; Humans; Kenya; Leukemia, Myeloid, Acute; Retrospective Studies; Treatment Outcome

2023
Development of Real-world Data-based Medication Instruction Sheet for Acute Myeloid Leukemia Patients Receiving High-dose Cytarabine Consolidation Therapy.
    Anticancer research, 2023, Volume: 43, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Consolidation Chemotherapy; Cytarabine; Humans; Leukemia, Myeloid, Acute; Remission Induction

2023
[Efficacy and Safety of Decitabine Combined with Modified CAG Regimen in Patients Aged ≥ 70 Years with Newly Diagnosed Acute Myeloid Leukemia].
    Zhongguo shi yan xue ye xue za zhi, 2023, Volume: 31, Issue:3

    Topics: Aged; Aged, 80 and over; Cytarabine; Decitabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Mutation; Prognosis; Retrospective Studies

2023
    Zhongguo shi yan xue ye xue za zhi, 2023, Volume: 31, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Cytarabine; Female; Forkhead Transcription Factors; Humans; Idarubicin; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Retrospective Studies; RNA, Messenger; T-Lymphocytes, Regulatory; Transforming Growth Factor beta

2023
The m6A modulator-mediated cytarabine sensitivity and immune cell infiltration signature in acute myeloid leukemia.
    Journal of cancer research and clinical oncology, 2023, Volume: 149, Issue:13

    Topics: Cytarabine; Humans; Leukemia, Myeloid, Acute; Methyltransferases; Recurrence; Tumor Microenvironment

2023
HLA-mismatched micro-transplantation as post-remission treatment compared to autologous hematopoietic stem cell transplantation or consolidation with single agent cytarabine for favorable-or intermediate-risk acute myeloid leukemia.
    Hematology (Amsterdam, Netherlands), 2023, Volume: 28, Issue:1

    Topics: Aged; Cytarabine; Hematopoietic Stem Cell Transplantation; HLA Antigens; Humans; Leukemia, Myeloid, Acute; Remission Induction; Retrospective Studies; Transplantation, Autologous

2023
Posttranslational splicing modifications as a key mechanism in cytarabine resistance in acute myeloid leukemia.
    Leukemia, 2023, Volume: 37, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Humans; Leukemia, Myeloid, Acute; RNA Splicing; Sulfonamides

2023
FLAG based v/s Standard 3 + 7 induction therapy in treatment naïve Acute Myeloid Leukemia: Time to think "beyond anthracyclines".
    Leukemia research, 2023, Volume: 132

    Topics: Adult; Anthracyclines; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Remission Induction; Retrospective Studies; Vidarabine

2023
Prolonged Survival Using Outpatient Palliative Chemotherapy in Two Children With Refractory Acute Myelogenous Leukemia.
    Journal of pediatric hematology/oncology, 2023, 08-01, Volume: 45, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Neoplasm, Residual; Outpatients; Quality of Life

2023
Real-World Experience With CPX-351 Treatment for Acute Myeloid Leukemia in England: An Analysis From the National Cancer Registration and Analysis Service.
    Clinical lymphoma, myeloma & leukemia, 2023, Volume: 23, Issue:10

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Retrospective Studies

2023
Etoposide plus cytarabine versus cyclophosphamide or melphalan in busulfan-based preparative regimens for autologous stem cell transplantation in adults with acute myeloid leukemia in first complete remission: a study from the Acute Leukemia Working Party
    Bone marrow transplantation, 2023, Volume: 58, Issue:11

    Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cyclophosphamide; Cytarabine; Etoposide; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Melphalan; Retrospective Studies; Transplantation Conditioning; Transplantation, Autologous

2023
Effect of Granulocyte Colony-Stimulating Factor on the Development of Spermatogenesis in the Adulthood of Juvenile AML Mice Model Treated with Cytarabine.
    International journal of molecular sciences, 2023, Jul-31, Volume: 24, Issue:15

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Granulocyte Colony-Stimulating Factor; Interleukin-10; Leukemia, Myeloid, Acute; Male; Mice; Semen; Spermatogenesis

2023
Core-binding factor abnormalities involving chromosome 16 in acute myeloid leukaemia: prognostic and therapeutic implications.
    BMJ case reports, 2023, Aug-17, Volume: 16, Issue:8

    Topics: Chromosomes, Human, Pair 16; Core Binding Factors; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Prognosis

2023
Fractionated vs single-dose gemtuzumab ozogamicin with determinants of benefit in older patients with AML: the UK NCRI AML18 trial.
    Blood, 2023, Nov-16, Volume: 142, Issue:20

    Topics: Aged; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; United Kingdom

2023
A small molecule BCL6 inhibitor as chemosensitizers in acute myeloid leukemia.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 166

    Topics: Apoptosis; Carcinogenesis; Carcinogens; Cell Cycle; Cytarabine; Humans; Leukemia, Myeloid, Acute; Proto-Oncogene Proteins c-bcl-6

2023
Outpatient consolidation chemotherapy with intermediate dose cytarabine has similar survival and relapses rates in acute myeloid leukemia as compared to high dose cytarabine: A single center analysis.
    European journal of haematology, 2023, Volume: 111, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Consolidation Chemotherapy; Cytarabine; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Outpatients; Prospective Studies; Remission Induction; Retrospective Studies

2023
E2F1 rs3213150 polymorphism influences cytarabine sensitivity and prognosis in patients with acute myeloid leukemia.
    Annals of hematology, 2023, Volume: 102, Issue:12

    Topics: Cytarabine; E2F1 Transcription Factor; Humans; Leukemia, Myeloid, Acute; Polymorphism, Single Nucleotide; Prognosis; Remission Induction

2023
[Acute myeloid leukemia with t (8;21) translocation diagnosed at 21 weeks of gestation resulting in full-term delivery without chemotherapy].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2023, Volume: 64, Issue:8

    Topics: Adult; Cesarean Section; Cytarabine; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Pregnancy; Translocation, Genetic

2023
Interleukin-6 Facilitates Acute Myeloid Leukemia Chemoresistance via Mitofusin 1-Mediated Mitochondrial Fusion.
    Molecular cancer research : MCR, 2023, 12-01, Volume: 21, Issue:12

    Topics: Animals; Cytarabine; Drug Resistance, Neoplasm; Humans; Interleukin-6; Leukemia, Myeloid, Acute; Mice; Mitochondrial Dynamics

2023
A novel anticancer quinolone, (R)-WAC-224, has anti-leukemia activities against acute myeloid leukemia.
    Investigational new drugs, 2023, Volume: 41, Issue:5

    Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Synergism; Humans; Leukemia, Myeloid, Acute; Mice; Quinolones

2023
Distinct and targetable role of calcium-sensing receptor in leukaemia.
    Nature communications, 2023, 10-06, Volume: 14, Issue:1

    Topics: Calcium; Cytarabine; Humans; Leukemia, Myeloid, Acute; Oncogene Proteins, Fusion; Proto-Oncogene Proteins c-myc; Receptors, Calcium-Sensing; Signal Transduction; Tumor Microenvironment

2023
Artesunate reverses cytarabine resistance in acute myeloid leukemia by blocking the JAK/STAT3 signaling.
    Hematology (Amsterdam, Netherlands), 2023, Volume: 28, Issue:1

    Topics: Artesunate; Cytarabine; Humans; Janus Kinases; Leukemia, Myeloid, Acute; Signal Transduction; STAT3 Transcription Factor

2023
Research on the preparation process of the cytarabine/daunorubicin dual-encapsulation liposome and its physicochemical properties and performances in vitro/vivo.
    International journal of pharmaceutics, 2023, Nov-05, Volume: 646

    Topics: Copper; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Liposomes

2023
Efficacy of venetoclax combined with hypomethylating agents in young, and unfit patients with newly diagnosed core binding factor acute myeloid leukemia.
    Blood cancer journal, 2023, 10-11, Volume: 13, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Core Binding Factors; Cytarabine; Humans; Leukemia, Myeloid, Acute

2023
Identification of cellular senescence-related signature for predicting prognosis and therapeutic response of acute myeloid leukemia.
    Aging, 2023, 10-13, Volume: 15, Issue:20

    Topics: Area Under Curve; Cellular Senescence; Cytarabine; Humans; Leukemia, Myeloid, Acute; Prognosis; Tumor Microenvironment

2023
A new sequential conditioning regimen based on CPX- 351/Vyxeos ("Vyx-Seq") in patients with higher risk myelodysplastic syndromes.
    Leukemia research, 2023, Volume: 135

    Topics: Cytarabine; Daunorubicin; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Transplantation Conditioning

2023
Spatiotemporal evolution of AML immune microenvironment remodeling and RNF149-driven drug resistance through single-cell multidimensional analysis.
    Journal of translational medicine, 2023, 10-27, Volume: 21, Issue:1

    Topics: Bone Marrow; Cytarabine; Drug Resistance; Humans; Leukemia, Myeloid, Acute; Tumor Microenvironment; Ubiquitin-Protein Ligases

2023
Non-haematological grade 1 and 2 adverse events of frontline CPX-351 in patients with myelodysplastic syndromes.
    The Lancet. Haematology, 2023, Volume: 10, Issue:11

    Topics: Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes

2023
8-Hydroxydaidzein Induces Apoptosis and Inhibits AML-Associated Gene Expression in U-937 Cells: Potential Phytochemical for AML Treatment.
    Biomolecules, 2023, Oct-26, Volume: 13, Issue:11

    Topics: Apoptosis; Cell Line, Tumor; Cytarabine; Gene Expression; Humans; Leukemia, Myeloid, Acute; Molecular Docking Simulation

2023
Non-allogeneic immunotherapy in acute myeloid leukaemia.
    The Lancet. Haematology, 2019, Volume: 6, Issue:9

    Topics: Cytarabine; Humans; Idarubicin; Immunotherapy; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Nivolumab

2019
Identification of predictive genetic signatures of Cytarabine responsiveness using a 3D acute myeloid leukaemia model.
    Journal of cellular and molecular medicine, 2019, Volume: 23, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Bone Marrow Cells; Cell Line, Tumor; Cytarabine; Female; Gene Expression Regulation, Leukemic; Humans; Inhibitory Concentration 50; Leukemia, Myeloid, Acute; Male; Middle Aged; Models, Biological; Mutation; Oncogene Proteins, Fusion; Treatment Outcome

2019
Simultaneous determination of cytosine arabinoside and its metabolite uracil arabinoside in human plasma by LC-MS/MS: Application to pharmacokinetics-pharmacogenetics pilot study in AML patients.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2019, Sep-15, Volume: 1126-1127

    Topics: Antimetabolites, Antineoplastic; Arabinofuranosyluracil; Chromatography, High Pressure Liquid; Cytarabine; Drug Monitoring; Humans; Leukemia, Myeloid, Acute; Linear Models; Pilot Projects; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry

2019
A New Conditioning Regimen Can Significantly Promote Post-Transplant Immune Reconstitution and Improve the Outcome of Umbilical Cord Blood Transplantation for Patients.
    Stem cells and development, 2019, 10-15, Volume: 28, Issue:20

    Topics: Adult; Anemia, Aplastic; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cord Blood Stem Cell Transplantation; Cyclophosphamide; Cytarabine; Female; Graft Survival; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Humans; Immune Reconstitution; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Primary Immunodeficiency Diseases; Semustine; Survival Analysis; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Unrelated Donors; Vidarabine

2019
PTEN/AKT signaling mediates chemoresistance in refractory acute myeloid leukemia through enhanced glycolysis.
    Oncology reports, 2019, Volume: 42, Issue:5

    Topics: Cell Line, Tumor; Cytarabine; Down-Regulation; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Glycolysis; HL-60 Cells; Humans; Idarubicin; Leukemia, Myeloid, Acute; Oxidative Phosphorylation; Phosphorylation; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Signal Transduction

2019
Fractionated gemtuzumab ozogamicin in association with high dose chemotherapy: a bridge to allogeneic stem cell transplantation in refractory and relapsed acute myeloid leukemia.
    Bone marrow transplantation, 2020, Volume: 55, Issue:2

    Topics: Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Gemtuzumab; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Salvage Therapy

2020
Glasdegib for the treatment of adult patients with newly diagnosed acute myeloid leukemia or high-grade myelodysplastic syndrome who are elderly or otherwise unfit for standard induction chemotherapy.
    Drugs of today (Barcelona, Spain : 1998), 2019, Volume: 55, Issue:9

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Clinical Trials, Phase II as Topic; Cytarabine; Drug Approval; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Phenylurea Compounds; Randomized Controlled Trials as Topic; United States; United States Food and Drug Administration

2019
Early hospital discharge after intensive induction chemotherapy for adults with acute myeloid leukemia or other high-grade myeloid neoplasm.
    Leukemia, 2020, Volume: 34, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Patient Discharge; Young Adult

2020
Inflammatory Cells in Atypical Eruption of Lymphocyte Recovery Carry the Same Mutations as Neoplastic Myeloid Cells.
    The American Journal of dermatopathology, 2020, Volume: 42, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Eruptions; Female; Humans; Idarubicin; Isocitrate Dehydrogenase; Leukemia, Myeloid, Acute; Mutation; Myelodysplastic Syndromes

2020
Acute Pancreatitis Associated With Cytarabine During the Treatment of Pediatric Acute Myeloid Leukemia.
    Journal of pediatric hematology/oncology, 2020, Volume: 42, Issue:1

    Topics: Child; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Pancreatitis

2020
Muscle aches and pains: do I have leukemia?
    International journal of hematology, 2020, Volume: 111, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Lower Extremity; Male; Myalgia

2020
Benzyl butyl phthalate (BBP) triggers the malignancy of acute myeloid leukemia cells via upregulation of PDK4.
    Toxicology in vitro : an international journal published in association with BIBRA, 2020, Volume: 62

    Topics: 5' Untranslated Regions; Adenosine Triphosphate; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Carcinogens; Cell Line, Tumor; Cell Proliferation; Cytarabine; Daunorubicin; Gene Expression Regulation, Neoplastic; Glycolysis; Humans; Leukemia, Myeloid, Acute; MicroRNAs; Phthalic Acids; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; RNA, Small Interfering; Up-Regulation

2020
An 1H NMR study of the cytarabine degradation in clinical conditions to avoid drug waste, decrease therapy costs and improve patient compliance in acute leukemia.
    Anti-cancer drugs, 2020, Volume: 31, Issue:1

    Topics: Antimetabolites, Antineoplastic; Chromatography, High Pressure Liquid; Cost Savings; Cytarabine; Drug Costs; Drug Stability; Drug Storage; Humans; Leukemia, Myeloid, Acute; Medication Adherence; Nuclear Magnetic Resonance, Biomolecular; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Solutions

2020
Disruption of gap junctions attenuates acute myeloid leukemia chemoresistance induced by bone marrow mesenchymal stromal cells.
    Oncogene, 2020, Volume: 39, Issue:6

    Topics: Animals; Anti-Ulcer Agents; Antimetabolites, Antineoplastic; Apoptosis; Carbenoxolone; Cell Proliferation; Cytarabine; Drug Resistance, Neoplasm; Drug Therapy, Combination; Gap Junctions; Humans; Leukemia, Myeloid, Acute; Mesenchymal Stem Cells; Mice; Mice, Inbred NOD; Mice, SCID; Tumor Cells, Cultured; Tumor Microenvironment; Xenograft Model Antitumor Assays

2020
A retrospective study of the correlation of in vitro chemosensitivity using ATP-TCA with patient clinical outcomes in acute myeloid leukemia.
    Cancer chemotherapy and pharmacology, 2020, Volume: 85, Issue:3

    Topics: Aclarubicin; Adult; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Decitabine; Female; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Remission Induction; Retrospective Studies; Young Adult

2020
Etoposide Combined with FLAG Salvage Therapy Is Effective in Multiple Relapsed/Refractory Acute Myeloid leukemia.
    Acta haematologica, 2020, Volume: 143, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Hemorrhage; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Remission Induction; Salvage Therapy; Vidarabine

2020
Systemic Metabolomic Profiling of Acute Myeloid Leukemia Patients before and During Disease-Stabilizing Treatment Based on All-Trans Retinoic Acid, Valproic Acid, and Low-Dose Chemotherapy.
    Cells, 2019, 10-10, Volume: 8, Issue:10

    Topics: Aged; Aged, 80 and over; Amino Acids; Cytarabine; Drug Therapy; Female; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Lipid Metabolism; Male; Mercaptopurine; Metabolomics; Middle Aged; Treatment Outcome; Tretinoin; Valproic Acid

2019
More options for older patients with acute myeloid leukemia: venetoclax in combination with low dose cytarabine.
    Chinese clinical oncology, 2019, Volume: 8, Issue:S1

    Topics: Aged; Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Sulfonamides

2019
Translesion synthesis DNA polymerases η, ι, and ν promote mutagenic replication through the anticancer nucleoside cytarabine.
    The Journal of biological chemistry, 2019, 12-13, Volume: 294, Issue:50

    Topics: Antimetabolites, Antineoplastic; Cytarabine; DNA Replication; DNA-Directed DNA Polymerase; Fibroblasts; Humans; Leukemia, Myeloid, Acute; Nucleic Acid Conformation

2019
FLAG With Bortezomib in Childhood Relapsed/Refractory Leukemia: Remission Induction With Limited Toxicity in the Era of Multidrug-resistant Bacteria.
    Journal of pediatric hematology/oncology, 2021, 03-01, Volume: 43, Issue:2

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bortezomib; Child; Child, Preschool; Cytarabine; Drug Resistance, Multiple, Bacterial; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Retrospective Studies; Vidarabine

2021
Loss of the Y chromosome predicts a high relapse risk in younger adult male patients with t(8;21) acute myeloid leukemia on high-dose cytarabine consolidation therapy: a retrospective multicenter study.
    Leukemia & lymphoma, 2020, Volume: 61, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Consolidation Chemotherapy; Cytarabine; Disease-Free Survival; Humans; Leukemia, Myeloid, Acute; Male; Recurrence; Retrospective Studies; Y Chromosome

2020
Improved chemotherapy modeling with RAG-based immune deficient mice.
    PloS one, 2019, Volume: 14, Issue:11

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cytarabine; Doxorubicin; Drug Administration Schedule; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Mice; Mice, SCID; Models, Theoretical; Treatment Outcome; Xenograft Model Antitumor Assays

2019
Re-induction with modified CLAG regimen in relapsed or refractory acute myeloid leukemia in children bridging to allogeneic hematopoietic stem cell transplantation.
    World journal of pediatrics : WJP, 2020, Volume: 16, Issue:2

    Topics: Adolescent; Antineoplastic Agents; Child; Child, Preschool; Cladribine; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Infant; Leukemia, Myeloid, Acute; Male; Neoplasm Recurrence, Local; Remission Induction; Retreatment; Retrospective Studies

2020
How I treat acute myeloid leukemia in the era of new drugs.
    Blood, 2020, 01-09, Volume: 135, Issue:2

    Topics: Adult; Aged; Aminopyridines; Aniline Compounds; Antineoplastic Agents; Biomarkers, Tumor; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Daunorubicin; Female; fms-Like Tyrosine Kinase 3; Glycine; Humans; Isocitrate Dehydrogenase; Leukemia, Myeloid, Acute; Male; Molecular Targeted Therapy; Mutation; Prognosis; Pyrazines; Pyridines; Sialic Acid Binding Ig-like Lectin 3; Staurosporine; Sulfonamides; Triazines

2020
Acute myeloid leukemia with a novel CPSF6-RARG variant is sensitive to homoharringtonine and cytarabine chemotherapy.
    American journal of hematology, 2020, Volume: 95, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Homoharringtonine; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; mRNA Cleavage and Polyadenylation Factors; Oncogene Proteins, Fusion; Receptors, Retinoic Acid; Retinoic Acid Receptor gamma

2020
Low-dose pembrolizumab induced complete radiologic and molecular response of posttransplant lymphoproliferative disorder presenting as classical Hodgkin lymphoma.
    Annals of hematology, 2020, Volume: 99, Issue:2

    Topics: Allografts; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Brentuximab Vedotin; Cytarabine; Daunorubicin; Epstein-Barr Virus Infections; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Hodgkin Disease; Humans; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Male; Molecular Targeted Therapy; Neoplasms, Second Primary; Postoperative Complications; Programmed Cell Death 1 Receptor; Protoporphyria, Erythropoietic; Recurrence; Remission Induction; Virus Activation; Young Adult

2020
Excellent outcome after consolidation with autologous transplantation in patients with core binding factor acute myeloid leukemia.
    Bone marrow transplantation, 2020, Volume: 55, Issue:8

    Topics: Core Binding Factors; Cytarabine; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Remission Induction; Transplantation, Autologous

2020
Prolonged administration of low-dose cytarabine and thioguanine in elderly patients with acute myeloid leukaemia (AML) achieves high complete remission rates and prolonged survival.
    Leukemia & lymphoma, 2020, Volume: 61, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Leukemia, Myeloid, Acute; Neoplasm Recurrence, Local; Remission Induction; Retrospective Studies; Thioguanine; Treatment Outcome

2020
Role of equilibrative nucleoside transporter 1 (ENT1) in the disposition of cytarabine in mice.
    Pharmacology research & perspectives, 2019, Volume: 7, Issue:6

    Topics: Animals; Antimetabolites, Antineoplastic; Cytarabine; Drug Interactions; Equilibrative Nucleoside Transporter 1; Female; Humans; Leukemia, Myeloid, Acute; Liver-Specific Organic Anion Transporter 1; Mice; Mice, Knockout; Organic Cation Transport Proteins; Symporters; Thioinosine

2019
Outpatient administration of liposomal daunorubicin and cytarabine (Vyxeos) in patients with secondary acute myeloid leukemia.
    Clinical advances in hematology & oncology : H&O, 2019, Volume: 17, Issue:11

    Topics: Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Liposomes; Neoplasms, Second Primary; Treatment Outcome

2019
Novel L-nucleoside analogue, 5-fluorotroxacitabine, displays potent efficacy against acute myeloid leukemia.
    Haematologica, 2021, 02-01, Volume: 106, Issue:2

    Topics: Cytarabine; Humans; Leukemia, Myeloid, Acute; Nucleosides

2021
Bilateral ovarian granulocytic sarcoma as the primary manifestation of acute myelogenous leukemia treated with allogenic stem cell transplantation: A case report.
    Medicine, 2019, Volume: 98, Issue:52

    Topics: Adult; Antimetabolites, Antineoplastic; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Ovarian Neoplasms; Sarcoma, Myeloid; Stem Cell Transplantation

2019
The Role of Anthracyclines in Acute Myeloid Leukemia Consolidation.
    Anticancer research, 2020, Volume: 40, Issue:1

    Topics: Adolescent; Adult; Aged; Anthracyclines; Consolidation Chemotherapy; Cytarabine; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Multivariate Analysis; Proportional Hazards Models; Young Adult

2020
Pregnancy exposure to midostaurin in the first trimester.
    Annals of hematology, 2020, Volume: 99, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cesarean Section; Compassionate Use Trials; Cytarabine; Female; Fetal Growth Retardation; fms-Like Tyrosine Kinase 3; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Leukemia, Myeloid, Acute; Mutation; Pregnancy; Pregnancy Complications, Neoplastic; Pregnancy Outcome; Pregnancy Trimester, First; Protein Kinase Inhibitors; Recurrence; Staurosporine; Tandem Repeat Sequences

2020
Secondary acquisition of BCR-ABL1 fusion in de novo GATA2-MECOM positive acute myeloid leukemia with subsequent emergence of a rare KMT2A-ASXL2 fusion.
    Cancer genetics, 2020, Volume: 241

    Topics: Cytarabine; Fusion Proteins, bcr-abl; GATA2 Transcription Factor; Humans; Leukemia, Myeloid, Acute; Male; MDS1 and EVI1 Complex Locus Protein; Middle Aged; Protein Kinase Inhibitors; Repressor Proteins

2020
HOTAIRM1 knockdown enhances cytarabine-induced cytotoxicity by suppression of glycolysis through the Wnt/β-catenin/PFKP pathway in acute myeloid leukemia cells.
    Archives of biochemistry and biophysics, 2020, 02-15, Volume: 680

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Cell Line, Tumor; Cytarabine; Gene Knockdown Techniques; Glycolysis; Humans; Leukemia, Myeloid, Acute; Phosphofructokinase-1, Type C; RNA, Long Noncoding; Signal Transduction; Wnt Signaling Pathway

2020
Loss of X chromosome predicts favorable prognosis in female patients with t(8;21) acute myeloid leukemia.
    Leukemia & lymphoma, 2020, Volume: 61, Issue:5

    Topics: Cytarabine; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Prognosis; Remission Induction; Retrospective Studies; X Chromosome

2020
Inhibition of mTORC1/P70S6K pathway by Metformin synergistically sensitizes Acute Myeloid Leukemia to Ara-C.
    Life sciences, 2020, Feb-15, Volume: 243

    Topics: Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Cytarabine; Drug Synergism; Humans; Leukemia, Myeloid, Acute; Mechanistic Target of Rapamycin Complex 1; Metformin; Mice; Mice, Inbred BALB C; Mice, Nude; Ribosomal Protein S6 Kinases, 70-kDa; Xenograft Model Antitumor Assays

2020
Acute cerebellar toxicity induced by high dose of cytarabine (HiDAC): A case report.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2020, Volume: 26, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cerebellum; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myeloid, Acute; Remission Induction; Young Adult

2020
Ribonucleotide reductase inhibitors suppress SAMHD1 ara-CTPase activity enhancing cytarabine efficacy.
    EMBO molecular medicine, 2020, 03-06, Volume: 12, Issue:3

    Topics: Animals; Arabinofuranosylcytosine Triphosphate; Cytarabine; Leukemia, Myeloid, Acute; Mice; Pyrophosphatases; Ribonucleotide Reductases; SAM Domain and HD Domain-Containing Protein 1

2020
Venetoclax plus hypomethylating agents or low-dose cytarabine in acute myeloid leukemia: all that glitters is gold?
    Blood cancer journal, 2020, 01-28, Volume: 10, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Humans; Leukemia, Myeloid, Acute; Sulfonamides

2020
Recurrent Isolated Hyperbilirubinemia From Drug-Induced Impaired Hepatic Bilirubin Uptake.
    Hepatology (Baltimore, Md.), 2020, Volume: 72, Issue:3

    Topics: Antimetabolites, Antineoplastic; Bilirubin; Chemical and Drug Induced Liver Injury; Cytarabine; Diagnosis, Differential; Female; Gilbert Disease; Humans; Hyperbilirubinemia; Leukemia, Myeloid, Acute; Liver; Medication Therapy Management; Patient Care Management; Young Adult

2020
Randomized Trial of Intermediate-dose Cytarabine in Induction and Consolidation Therapy in Adults with Acute Myeloid Leukemia.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2020, 07-01, Volume: 26, Issue:13

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Middle Aged; Remission Induction; Young Adult

2020
Liposomal encapsulated cytarabine and daunorubicin (CPX-351) for older patients with acute myeloid leukemia.
    Leukemia & lymphoma, 2020, Volume: 61, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Liposomes

2020
Post-remission therapy of adults aged 60 and older with acute myeloid leukemia in first complete remission: role of treatment intensity on the outcome.
    Annals of hematology, 2020, Volume: 99, Issue:4

    Topics: Aged; Aged, 80 and over; Allografts; Antineoplastic Combined Chemotherapy Protocols; Blood Component Transfusion; Combined Modality Therapy; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Retrospective Studies; Transplantation, Autologous; Treatment Outcome

2020
Detection of measurable residual disease may better predict outcomes than mutations based on next-generation sequencing in acute myeloid leukaemia with biallelic mutations of CEBPA.
    British journal of haematology, 2020, Volume: 190, Issue:4

    Topics: Adolescent; Adult; Aged; Alleles; Allografts; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; CCAAT-Enhancer-Binding Proteins; Combined Modality Therapy; Cytarabine; Female; Hematopoietic Stem Cell Transplantation; High-Throughput Nucleotide Sequencing; Humans; Idarubicin; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Proteins; Neoplasm, Residual; Prognosis; Progression-Free Survival; Recurrence; Risk Assessment; Young Adult

2020
Final safety and efficacy results from the CPX-351 early access program for older patients with high-risk or secondary acute myeloid leukemia.
    Leukemia & lymphoma, 2020, Volume: 61, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute

2020
Real-world data on treatment patterns and outcomes of hypomethylating therapy in patients with newly diagnosed acute myeloid leukaemia aged ≥ 60 years.
    British journal of haematology, 2020, Volume: 189, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Decitabine; Disease-Free Survival; Female; Follow-Up Studies; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Male; Middle Aged; Retrospective Studies; Survival Rate

2020
Improved Post remission survival of non- favorable risk Acute Myelogenous Leukemia (AML) patients following initial remission induction therapy with FLAG+/-Idarubicin versus 3 + 7 (Anthracycline + Cytarabine).
    Leukemia research, 2020, Volume: 93

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Risk Factors; Survival Rate; Vidarabine

2020
Successful Umbilical Cord Blood Transplantation With Reduced-intensity Conditioning for Acute Myeloid Leukemia in a Child With Shwachman-Diamond Syndrome.
    Journal of pediatric hematology/oncology, 2021, 04-01, Volume: 43, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Child; Cytarabine; Female; Fetal Blood; Humans; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Melphalan; Myeloablative Agonists; Shwachman-Diamond Syndrome; Transplantation Conditioning; Vidarabine

2021
MEC (mitoxantrone, etoposide, and cytarabine) induces complete remission and is an effective bridge to transplant in acute myeloid leukemia.
    European journal of haematology, 2020, Volume: 105, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease Management; Etoposide; Hematopoietic Stem Cell Transplantation; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Mitoxantrone; Preoperative Care; Prognosis; Recurrence; Treatment Outcome

2020
UGT1A1 genotype influences clinical outcome in patients with intermediate-risk acute myeloid leukemia treated with cytarabine-based chemotherapy.
    Leukemia, 2020, Volume: 34, Issue:11

    Topics: Alleles; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cause of Death; Cytarabine; Female; Genotype; Glucuronosyltransferase; Humans; Leukemia, Myeloid, Acute; Male; Prognosis; Proportional Hazards Models; Recurrence; Remission Induction; Retrospective Studies; Treatment Outcome

2020
Venetoclax for paediatric acute myeloid leukaemia: a step forward.
    The Lancet. Oncology, 2020, Volume: 21, Issue:4

    Topics: Bridged Bicyclo Compounds, Heterocyclic; Child; Cytarabine; Humans; Idarubicin; Leukemia, Myeloid, Acute; Sulfonamides

2020
Association of immunophenotype with expression of topoisomerase II α and β in adult acute myeloid leukemia.
    Scientific reports, 2020, 03-26, Volume: 10, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antigens, CD; Antineoplastic Agents; Cohort Studies; Cytarabine; Daunorubicin; DNA Topoisomerases, Type II; Female; Humans; Immunophenotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Poly-ADP-Ribose Binding Proteins; RNA, Messenger; Topoisomerase II Inhibitors; Treatment Outcome; Young Adult

2020
[Successful delivery after chemotherapy for acute myeloid leukemia diagnosed in the second trimester].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2020, Volume: 61, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cesarean Section; Cytarabine; Daunorubicin; Female; Humans; Japan; Leukemia, Myeloid, Acute; Pregnancy; Pregnancy Complications, Neoplastic; Pregnancy Trimester, Second; Remission Induction; Retrospective Studies

2020
Clinical efficacy of decitabine‑containing induction chemotherapy in de novo non‑elderly acute myeloid leukemia.
    International journal of oncology, 2020, Volume: 56, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Decitabine; DNA Methylation; Female; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Survival Analysis; Treatment Outcome; Young Adult

2020
Decitabine in combination with low-dose cytarabine, aclarubicin and G-CSF tends to improve prognosis in elderly patients with high-risk AML.
    Aging, 2020, 04-01, Volume: 12, Issue:7

    Topics: Aclarubicin; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Decitabine; Disease-Free Survival; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Survival Rate; Treatment Outcome

2020
The Hi's and Lo's of Cytarabine in Acute Myeloid Leukemia.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2020, 07-01, Volume: 26, Issue:13

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; China; Consolidation Chemotherapy; Cytarabine; Humans; Leukemia, Myeloid, Acute; Treatment Outcome

2020
Feasibility and Outcome of a Phase II Study of Intensive Induction Chemotherapy in 91 Elderly Patients with AML Evaluated Using a Simplified Multidimensional Geriatric Assessment.
    Advances in therapy, 2020, Volume: 37, Issue:5

    Topics: Aged; Amifostine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Feasibility Studies; Female; Gemtuzumab; Geriatric Assessment; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Outcome Assessment, Health Care; Survival Analysis

2020
Ubiquitin and SUMO conjugation as biomarkers of acute myeloid leukemias response to chemotherapies.
    Life science alliance, 2020, Volume: 3, Issue:6

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cell Survival; Cytarabine; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Protein Array Analysis; SUMO-1 Protein; Sumoylation; Treatment Outcome; Ubiquitin; Young Adult

2020
Patterns of care and clinical outcomes with cytarabine-anthracycline induction chemotherapy for AML patients in the United States.
    Blood advances, 2020, 04-28, Volume: 4, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anthracyclines; Cytarabine; Female; Hospital Mortality; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; United States; Young Adult

2020
A multi-institutional comparison of mitoxantrone, etoposide, and cytarabine vs high-dose cytarabine and mitoxantrone therapy for patients with relapsed or refractory acute myeloid leukemia.
    American journal of hematology, 2020, Volume: 95, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Recurrence; Young Adult

2020
Isolated trisomy 11 in patients with acute myeloid leukemia - is the prognosis not as grim as previously thought?
    Leukemia & lymphoma, 2020, Volume: 61, Issue:9

    Topics: Cytarabine; Humans; Leukemia, Myeloid, Acute; Prognosis; Trisomy

2020
Targeting Cellular Metabolism in Acute Myeloid Leukemia and The Role of Patient Heterogeneity.
    Cells, 2020, 05-07, Volume: 9, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Apoptosis; Bridged Bicyclo Compounds, Heterocyclic; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cluster Analysis; Cytarabine; Deoxyglucose; Female; fms-Like Tyrosine Kinase 3; Gene Expression Regulation, Leukemic; Genetic Heterogeneity; Humans; Karyotype; Leukemia, Myeloid, Acute; Male; Mesenchymal Stem Cells; Middle Aged; Mutation; Nuclear Proteins; Nucleophosmin; Proteomics; Sulfonamides; Survival Analysis; Young Adult

2020
[Clinical outcome of CAG regimen in 26 children with aucte myeloid leukemia].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2019, 07-14, Volume: 40, Issue:7

    Topics: Aclarubicin; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Remission Induction; Treatment Outcome

2019
Linezolid is safe on platelet count for AML patients during myelosuppression after consolidation chemotherapy.
    Journal of clinical pharmacy and therapeutics, 2020, Volume: 45, Issue:4

    Topics: Adult; Anti-Bacterial Agents; Bone Marrow; Consolidation Chemotherapy; Cytarabine; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Linezolid; Male; Middle Aged; Platelet Count; Retrospective Studies; Thrombocytopenia

2020
Model-Based Optimal AML Consolidation Treatment.
    IEEE transactions on bio-medical engineering, 2020, Volume: 67, Issue:12

    Topics: Bone Marrow; Cytarabine; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute

2020
Venetoclax is safe and efficacious in relapsed/refractory AML.
    Leukemia & lymphoma, 2020, Volume: 61, Issue:9

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Neoplasm Recurrence, Local; Retrospective Studies; Sulfonamides

2020
TUG1 weakens the sensitivity of acute myeloid leukemia cells to cytarabine by regulating miR-655-3p/CCND1 axis.
    European review for medical and pharmacological sciences, 2020, Volume: 24, Issue:9

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Cell Proliferation; Cells, Cultured; Cyclin D1; Cytarabine; Humans; Leukemia, Myeloid, Acute; MicroRNAs; RNA, Long Noncoding

2020
Inhibition of ubiquitin-specific protease 7 sensitizes acute myeloid leukemia to chemotherapy.
    Leukemia, 2021, Volume: 35, Issue:2

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Biomarkers, Tumor; Cell Proliferation; Cytarabine; Drug Resistance, Neoplasm; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Myeloid, Acute; Male; Mice; Mice, Inbred NOD; Mice, SCID; Middle Aged; Prognosis; RNA, Small Interfering; Signal Transduction; Survival Rate; Tumor Cells, Cultured; Ubiquitin-Specific Peptidase 7; Xenograft Model Antitumor Assays

2021
Classic and targeted anti-leukaemic agents interfere with the cholesterol biogenesis metagene in acute myeloid leukaemia: Therapeutic implications.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:13

    Topics: Adult; Aged; Aged, 80 and over; Apoptosis; Benzothiazoles; Biosynthetic Pathways; Cell Line, Tumor; Cell Proliferation; Cholesterol; Cytarabine; Down-Regulation; Female; Gene Expression Regulation, Leukemic; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intracellular Space; Leukemia, Myeloid, Acute; Male; Middle Aged; Phenylurea Compounds; Rosuvastatin Calcium; Translational Research, Biomedical; Young Adult

2020
Aldehyde dehydrogenase 3a2 protects AML cells from oxidative death and the synthetic lethality of ferroptosis inducers.
    Blood, 2020, 09-10, Volume: 136, Issue:11

    Topics: Aldehyde Oxidoreductases; Aldehydes; Animals; Carbolines; Cell Line, Tumor; Cyclohexylamines; Cytarabine; Doxorubicin; Ferroptosis; Hematopoiesis; Humans; Leukemia, Myeloid, Acute; Lipid Peroxidation; Mice; Mice, Inbred C57BL; Mice, Knockout; Myeloid-Lymphoid Leukemia Protein; Neoplasm Proteins; Oleic Acid; Oncogene Proteins, Fusion; Oxidation-Reduction; Oxidative Stress; Phenylenediamines; Phospholipid Hydroperoxide Glutathione Peroxidase

2020
A novel PrECOG (PrE0901) dose-escalation trial using eltrombopag: enhanced platelet recovery during consolidation therapy in acute myeloid leukemia.
    Leukemia & lymphoma, 2020, Volume: 61, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Benzoates; Consolidation Chemotherapy; Cytarabine; Humans; Hydrazines; Leukemia, Myeloid, Acute; Pyrazoles

2020
Diffuse alveolar hemorrhage during induction therapy for acute myeloid leukemia with inv(16)(p13.1q22).
    International journal of hematology, 2020, Volume: 112, Issue:2

    Topics: Chromosome Inversion; Chromosomes, Human, Pair 16; Cytarabine; Diagnosis, Differential; Hemorrhage; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Lung Diseases; Male; Middle Aged; Pulmonary Alveoli; Tomography, X-Ray Computed

2020
FLAG-Ida is back in.
    Leukemia research, 2020, Volume: 95

    Topics: Anthracyclines; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Remission Induction

2020
Acute myeloid leukemia with a severe coagulopathy and t(8;16)(p11;p13).
    American journal of hematology, 2021, Volume: 96, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Blood Coagulation Disorders; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 8; Cytarabine; Daunorubicin; Dexamethasone; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Male; Translocation, Genetic; Tretinoin

2021
[Efficacy of Small Dose HAG Regimen Combined with Decitabine in Treatment of Elderly Patients with Acute Myeloid Leukemia].
    Zhongguo shi yan xue ye xue za zhi, 2020, Volume: 28, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Decitabine; Disease-Free Survival; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Survival Rate; Treatment Outcome

2020
[Clinical Comparation of Two Kinds of Chemotherapy Regimens in the Treatment of Patients with MDS-RAEB/AML-MRC].
    Zhongguo shi yan xue ye xue za zhi, 2020, Volume: 28, Issue:3

    Topics: Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Decitabine; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Retrospective Studies; Treatment Outcome

2020
Targeting GLUT1 in acute myeloid leukemia to overcome cytarabine resistance.
    Haematologica, 2021, 04-01, Volume: 106, Issue:4

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Glucose Transporter Type 1; Humans; Leukemia, Myeloid, Acute

2021
Tandem Allogeneic Hematopoietic Stem Cell Transplantation for Salvage Treatment of Acute Myeloid Leukemia Refractory to Induction Chemotherapy: A Case Report.
    Transplantation proceedings, 2020, Volume: 52, Issue:8

    Topics: Adult; Busulfan; Cladribine; Cyclophosphamide; Cytarabine; Female; Hematopoietic Stem Cell Transplantation; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Melphalan; Mitoxantrone; Salvage Therapy; Transplantation Conditioning

2020
Aprepitant Sensitizes Acute Myeloid Leukemia Cells to the Cytotoxic Effects of Cytosine Arabinoside in vitro and in vivo.
    Drug design, development and therapy, 2020, Volume: 14

    Topics: Animals; Antineoplastic Agents; Aprepitant; Cell Cycle Checkpoints; Cell Proliferation; Cell Survival; Cytarabine; Drug Screening Assays, Antitumor; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Mice; Neoplasms, Experimental

2020
Concerns about how to use established minimal residual disease monitoring in the treatment of NPM1-mutant acute myeloid leukaemia (AML) following reduced intensity chemotherapy protocols for AML given as a result of the COVID-19 pandemic.
    British journal of haematology, 2020, Volume: 190, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; COVID-19; COVID-19 Drug Treatment; Cytarabine; Daunorubicin; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Male; Mutation; Neoplasm, Residual; Nuclear Proteins; Nucleophosmin; SARS-CoV-2

2020
Extracellular ATP and CD39 Activate cAMP-Mediated Mitochondrial Stress Response to Promote Cytarabine Resistance in Acute Myeloid Leukemia.
    Cancer discovery, 2020, Volume: 10, Issue:10

    Topics: Antigens, CD; Apyrase; Cytarabine; Drug Resistance, Neoplasm; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitochondria

2020
Dose-Reduced Decitabine Might Bring Benefits for Elderly AML Patients with Complex Karyotype: a Case Report.
    Clinical laboratory, 2020, Jul-01, Volume: 66, Issue:7

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Decitabine; Humans; Karyotype; Leukemia, Myeloid, Acute; Remission Induction; Treatment Outcome

2020
Survival outcomes and clinical benefit in patients with acute myeloid leukemia treated with glasdegib and low-dose cytarabine according to response to therapy.
    Journal of hematology & oncology, 2020, 07-14, Volume: 13, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Blood Transfusion; Cause of Death; Clinical Trials, Phase II as Topic; Combined Modality Therapy; Cytarabine; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Molecular Targeted Therapy; Multicenter Studies as Topic; Phenylurea Compounds; Randomized Controlled Trials as Topic; Remission Induction; Treatment Outcome

2020
A strategy to reduce cumulative anthracycline exposure in low-risk pediatric acute myeloid leukemia while maintaining favorable outcomes.
    Leukemia research, 2020, Volume: 96

    Topics: Adolescent; Adult; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Cardiotoxicity; Child; Child, Preschool; Cytarabine; Dose-Response Relationship, Drug; Doxorubicin; Female; Follow-Up Studies; Humans; Infant; Leukemia, Myeloid, Acute; Male; Neoplasm Recurrence, Local; Prognosis; Retrospective Studies; Survival Rate; Young Adult

2020
Proteome activity landscapes of tumor cell lines determine drug responses.
    Nature communications, 2020, 07-20, Volume: 11, Issue:1

    Topics: Adenylate Kinase; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Computational Biology; Computer Simulation; Cytarabine; Drug Development; Genomics; Humans; Leukemia, Myeloid, Acute; Neoplasms; Proteome; Proteomics; Raloxifene Hydrochloride; Receptors, Progesterone; Signal Transduction

2020
Risk of tumor lysis syndrome in patients with acute myeloid leukemia treated with venetoclax-containing regimens without dose ramp-up.
    Annals of hematology, 2021, Volume: 100, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Azacitidine; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Decitabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Risk Factors; Sulfonamides; Tumor Lysis Syndrome

2021
Towards better combination regimens of cytarabine and FLT3 inhibitors in acute myeloid leukemia.
    Cancer chemotherapy and pharmacology, 2020, Volume: 86, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzothiazoles; Biomarkers, Tumor; Cell Cycle; Cell Movement; Cell Proliferation; Cytarabine; fms-Like Tyrosine Kinase 3; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Myeloid, Acute; Mutation; Phenylurea Compounds; Prognosis; Survival Rate; Tumor Cells, Cultured

2020
Immunosuppressive role of CD11b
    Cancer medicine, 2020, Volume: 9, Issue:19

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; CD11b Antigen; Cell Line, Tumor; Cell Proliferation; Coculture Techniques; Cytarabine; Cytotoxicity, Immunologic; Female; Hematopoietic Stem Cell Transplantation; HLA-DR Antigens; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Myeloid-Derived Suppressor Cells; Phenotype; Sialic Acid Binding Ig-like Lectin 3; T-Lymphocytes, Cytotoxic; Treatment Outcome; Tumor Escape

2020
Allogeneic stem cell transplantation mitigates the adverse prognostic impact of high diagnostic BAALC and MN1 expression in AML.
    Annals of hematology, 2020, Volume: 99, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Allografts; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Female; Gene Dosage; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Proteins; Peripheral Blood Stem Cell Transplantation; Polymerase Chain Reaction; Prognosis; Proto-Oncogene Proteins c-abl; Trans-Activators; Treatment Outcome; Tumor Suppressor Proteins; Young Adult

2020
Pharmacological strategies to overcome treatment resistance in acute myeloid leukemia: increasing leukemic drug exposure by targeting the resistance factor SAMHD1 and the toxicity factor Top2β.
    Expert opinion on drug discovery, 2021, Volume: 16, Issue:1

    Topics: Anthracyclines; Antineoplastic Agents; Cytarabine; DNA Topoisomerases, Type II; Drug Resistance, Neoplasm; Humans; Leukemia, Myeloid, Acute; Molecular Targeted Therapy; Poly-ADP-Ribose Binding Proteins; SAM Domain and HD Domain-Containing Protein 1

2021
Antibiotic use during cytarabine consolidation in acute myeloid leukemia.
    Annals of hematology, 2021, Volume: 100, Issue:1

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Antimetabolites, Antineoplastic; Consolidation Chemotherapy; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Retrospective Studies; Young Adult

2021
Acute pancreatitis induced by combination chemotherapy used for the treatment of acute myeloid leukemia: A case report.
    Medicine, 2020, Aug-28, Volume: 99, Issue:35

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dasatinib; Daunorubicin; Female; Homoharringtonine; Humans; Leukemia, Myeloid, Acute; Pancreatitis; Tomography, X-Ray Computed

2020
Attempts to optimize postinduction treatment in childhood acute myeloid leukemia without core-binding factors: A report from the Japanese Pediatric Leukemia/Lymphoma Study Group (JPLSG).
    Pediatric blood & cancer, 2020, Volume: 67, Issue:12

    Topics: Adolescent; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined Modality Therapy; Core Binding Factors; Cytarabine; Etoposide; Female; Follow-Up Studies; Humans; Induction Chemotherapy; Infant; Japan; Leukemia, Myeloid, Acute; Male; Mutation; Prognosis; Remission Induction; Retrospective Studies; Societies, Medical; Stem Cell Transplantation; Survival Rate

2020
Sequential treatment with FLAG-IDA/treosulfan conditioning regimen for patients with active acute myeloid leukemia.
    Annals of hematology, 2020, Volume: 99, Issue:12

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cohort Studies; Cytarabine; Disease-Free Survival; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Retrospective Studies; Transplantation Conditioning; Treatment Outcome; Vidarabine; Young Adult

2020
DNA Methylation-Based Epigenetic Repression of SLC22A4 Promotes Resistance to Cytarabine in Acute Myeloid Leukemia.
    Clinical and translational science, 2021, Volume: 14, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cell Line, Tumor; Child; Clinical Trials, Phase III as Topic; Cytarabine; Datasets as Topic; Decitabine; DNA Methylation; Drug Resistance, Neoplasm; Epigenetic Repression; Female; Gene Expression Regulation, Leukemic; HEK293 Cells; Humans; Leukemia, Myeloid, Acute; Male; Organic Cation Transport Proteins; Progression-Free Survival; Randomized Controlled Trials as Topic; Symporters; Young Adult

2021
BCL6 maintains survival and self-renewal of primary human acute myeloid leukemia cells.
    Blood, 2021, 02-11, Volume: 137, Issue:6

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Self Renewal; Cytarabine; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Gene Knockdown Techniques; Hematopoietic Stem Cells; Humans; Indoles; Leukemia, Myeloid, Acute; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Proteins; Neoplastic Stem Cells; Proto-Oncogene Mas; Proto-Oncogene Proteins c-bcl-6; Radiation Chimera; RNA Interference; RNA-Seq; RNA, Messenger; RNA, Neoplasm; RNA, Small Interfering; Thiazolidinediones; Tumor Stem Cell Assay; Xenograft Model Antitumor Assays

2021
Comparison of outpatient care following intensive induction versus post-remission chemotherapy for adults with acute myeloid leukemia and other high-grade myeloid neoplasms.
    Leukemia & lymphoma, 2021, Volume: 62, Issue:1

    Topics: Adult; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Remission Induction

2021
Secondary chronic myeloid leukemia following acute myeloid leukemia treated with autologous hematopoietic stem cell transplantation: a case report.
    Current medical research and opinion, 2020, Volume: 36, Issue:11

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Etoposide; Hematopoietic Stem Cell Transplantation; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Pyrimidines; Remission Induction; Transplantation, Autologous

2020
A Screening of Antineoplastic Drugs for Acute Myeloid Leukemia Reveals Contrasting Immunogenic Effects of Etoposide and Fludarabine.
    International journal of molecular sciences, 2020, Sep-16, Volume: 21, Issue:18

    Topics: Adenosine Triphosphate; Alarmins; Antineoplastic Agents; Calreticulin; Cell Line, Tumor; Cytarabine; Daunorubicin; Dendritic Cells; Etoposide; Extracellular Space; Gene Expression Regulation, Neoplastic; Heat-Shock Proteins; Humans; Immunogenic Cell Death; Leukemia, Myeloid, Acute; Lymphocyte Activation; Neoplasm Proteins; Organelles; Protein Transport; T-Lymphocyte Subsets; Vidarabine

2020
Postremission therapy with repeated courses of high-dose cytarabine, idarubicin, and limited autologous stem cell support achieves a very good long-term outcome in European leukemia net favorable and intermediate-risk acute myeloid leukemia.
    Hematological oncology, 2020, Volume: 38, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Daunorubicin; Female; Hematopoietic Stem Cell Transplantation; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Survival Analysis; Transplantation, Autologous; Treatment Outcome; Young Adult

2020
The outcomes of relapsed acute myeloid leukemia in children: Results from the Japanese Pediatric Leukemia/Lymphoma Study Group AML-05R study.
    Pediatric blood & cancer, 2021, Volume: 68, Issue:1

    Topics: Adolescent; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Etoposide; Female; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Humans; Infant; Leukemia, Myeloid, Acute; Male; Neoplasm Recurrence, Local; Prognosis; Retrospective Studies; Survival Rate; Transplantation, Homologous; Vidarabine

2021
Compassionate use of glasdegib in combination with low-dose cytarabine for relapsed, refractory acute myeloid leukemia or high-risk myelodysplastic syndrome.
    Annals of hematology, 2021, Volume: 100, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Compassionate Use Trials; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Phenylurea Compounds

2021
An evaluation of no-treatment decisions in patients with newly diagnosed acute myeloid leukemia.
    American journal of hematology, 2021, Volume: 96, Issue:1

    Topics: Adolescent; Adult; Aftercare; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Clinical Decision-Making; Cytarabine; Databases, Factual; Disease-Free Survival; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Survival Rate

2021
Accuracy of SIE/SIES/GITMO Consensus Criteria for Unfitness to Predict Early Mortality After Intensive Chemotherapy in Adults With AML or Other High-Grade Myeloid Neoplasm.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2020, 12-10, Volume: 38, Issue:35

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Consensus; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Induction Chemotherapy; Italy; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Myeloproliferative Disorders; Neoplasm Grading; Predictive Value of Tests; Severity of Illness Index; Survival Rate; Young Adult

2020
Venetoclax and alvocidib are both cytotoxic to acute myeloid leukemia cells resistant to cytarabine and clofarabine.
    BMC cancer, 2020, Oct-12, Volume: 20, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Cell Proliferation; Clofarabine; Cytarabine; Flavonoids; Humans; Leukemia, Myeloid, Acute; Piperidines; Sulfonamides

2020
Benefit of intermediate-dose cytarabine containing induction in molecular subgroups of acute myeloid leukemia.
    Haematologica, 2020, 09-28, Volume: 106, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Remission Induction; Treatment Outcome

2020
A pediatric case of acute myeloid leukemia with KMT2A gene rearrangement t(10;11) and 16p11.2 microdeletion syndrome.
    Pediatric blood & cancer, 2021, Volume: 68, Issue:2

    Topics: Antineoplastic Agents; Autistic Disorder; Child; Chromosome Deletion; Chromosome Disorders; Chromosomes, Human, Pair 16; Cytarabine; Daunorubicin; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Histone-Lysine N-Methyltransferase; Humans; Intellectual Disability; Leukemia, Myeloid, Acute; Mitogen-Activated Protein Kinase 3; Myeloid-Lymphoid Leukemia Protein; Vault Ribonucleoprotein Particles

2021
The effects of cytarabine combined with ginsenoside compound K synergistically induce DNA damage in acute myeloid leukemia cells.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 132

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytarabine; DNA Damage; Drug Resistance, Neoplasm; Drug Synergism; Ginsenosides; Humans; Leukemia, Myeloid, Acute; Mitochondria

2020
[Curative Efficacy and Survival Analysis of Low-Intensity Traditional Chemotherapy Regimen in the Elderly Patients with Acute Myeloid Leukemia (non-M
    Zhongguo shi yan xue ye xue za zhi, 2020, Volume: 28, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; China; Cytarabine; Humans; Leukemia, Myeloid, Acute; Retrospective Studies; Survival Analysis

2020
Gene expression profile predicts response to the combination of tosedostat and low-dose cytarabine in elderly AML.
    Blood advances, 2020, 10-27, Volume: 4, Issue:20

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Glycine; Humans; Hydroxamic Acids; Leukemia, Myeloid, Acute; Microarray Analysis; Transcriptome

2020
MicroRNA-143 sensitizes acute myeloid leukemia cells to cytarabine via targeting ATG7- and ATG2B-dependent autophagy.
    Aging, 2020, 10-19, Volume: 12, Issue:20

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Autophagy; Autophagy-Related Protein 7; Autophagy-Related Proteins; Caspase 3; Caspase 9; Cytarabine; Dose-Response Relationship, Drug; Gene Expression Regulation, Leukemic; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; MicroRNAs; Signal Transduction; U937 Cells; Vesicular Transport Proteins

2020
Diagnosis of oesophageal mucormycosis managed with medical therapy alone.
    BMJ case reports, 2020, Oct-22, Volume: 13, Issue:10

    Topics: Amphotericin B; Antifungal Agents; Cytarabine; Esophageal Diseases; Esophagus; Humans; Idarubicin; Immunocompromised Host; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Mucormycosis; Rhizopus; Triazoles

2020
Prognostic and therapeutic impacts of mutant TP53 variant allelic frequency in newly diagnosed acute myeloid leukemia.
    Blood advances, 2020, 11-24, Volume: 4, Issue:22

    Topics: Cytarabine; Humans; Leukemia, Myeloid, Acute; Prognosis; Retrospective Studies; Tumor Suppressor Protein p53

2020
Venetoclax + hypomethylating agents combined with dose-adjusted HAG for relapsed/refractory acute myeloid leukemia: Two case reports.
    Medicine, 2020, Nov-20, Volume: 99, Issue:47

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Decitabine; Drug Combinations; Fatal Outcome; Granulocyte Colony-Stimulating Factor; Homoharringtonine; Humans; Leukemia, Myeloid, Acute; Male; Neoplasm Recurrence, Local; Sulfonamides; Young Adult

2020
Treatment of refractory acute myeloid leukaemia during pregnancy with venetoclax, high-dose cytarabine and mitoxantrone.
    British journal of haematology, 2021, Volume: 192, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Pregnancy; Pregnancy Complications, Neoplastic; Sulfonamides

2021
Renin angiotensin system genes are biomarkers for personalized treatment of acute myeloid leukemia with Doxorubicin as well as etoposide.
    PloS one, 2020, Volume: 15, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Cell Line, Tumor; Computer Simulation; Cytarabine; Datasets as Topic; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Gene Ontology; Humans; Inhibitory Concentration 50; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Nonlinear Dynamics; Precision Medicine; Prognosis; Real-Time Polymerase Chain Reaction; Renin-Angiotensin System; Tretinoin

2020
Incidence of tumor lysis syndrome in patients with acute myeloid leukemia undergoing low-intensity induction with venetoclax.
    American journal of hematology, 2021, 03-01, Volume: 96, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Decitabine; Female; Fluid Therapy; Humans; Hydroxyurea; Incidence; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukocytosis; Male; Middle Aged; Phosphate-Binding Proteins; Phosphorus; Proto-Oncogene Proteins c-bcl-2; Retrospective Studies; Sulfonamides; Tumor Lysis Syndrome; Urate Oxidase; Uric Acid

2021
miR-10a as a therapeutic target and predictive biomarker for MDM2 inhibition in acute myeloid leukemia.
    Leukemia, 2021, Volume: 35, Issue:7

    Topics: Animals; Antineoplastic Agents; Apoptosis; Autophagy; Biomarkers, Tumor; Cell Line, Tumor; Cytarabine; Female; Humans; Imidazoles; Leukemia, Myeloid, Acute; Mice; Mice, Inbred NOD; MicroRNAs; Piperazines; Proto-Oncogene Proteins c-mdm2

2021
miR-15a-5p and miR-21-5p contribute to chemoresistance in cytogenetically normal acute myeloid leukaemia by targeting PDCD4, ARL2 and BTG2.
    Journal of cellular and molecular medicine, 2021, Volume: 25, Issue:1

    Topics: Apoptosis; Blotting, Western; Cell Line, Tumor; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Humans; Leukemia, Myeloid, Acute; MicroRNAs; Mutation; Nuclear Proteins; Nucleophosmin; Principal Component Analysis; RNA, Small Interfering

2021
Does patient fitness play a role in determining first-line treatment of acute myeloid leukemia?
    Hematology. American Society of Hematology. Education Program, 2020, 12-04, Volume: 2020, Issue:1

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Patient Selection; Sulfonamides

2020
Challenges in treatment of patients with acute leukemia and COVID-19: a series of 12 patients.
    Blood advances, 2020, 12-08, Volume: 4, Issue:23

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Azacitidine; COVID-19; Cytarabine; Extracorporeal Membrane Oxygenation; Female; Humans; Leukemia, B-Cell; Leukemia, Myeloid, Acute; Male; Middle Aged; Reverse Transcriptase Polymerase Chain Reaction; RNA, Viral; SARS-CoV-2; Treatment Outcome

2020
The association of leukocyte immunoglobulin-like receptor subfamily B-4 expression in acute myeloid leukemia and central nervous system involvement.
    Leukemia research, 2021, Volume: 100

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Child; Child, Preschool; Cytarabine; Female; Follow-Up Studies; Humans; Idarubicin; Infant; Leukemia, Myeloid, Acute; Male; Membrane Glycoproteins; Middle Aged; Prognosis; Prospective Studies; Receptors, Immunologic; Survival Rate; Young Adult

2021
Recurrent and reversible bilateral palmar blue discoloration following administration of liposomal daunorubicin-cytarabine (Vyxeos®) for acute myeloid leukemia with myelodysplasia-related changes.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2021, Volume: 27, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Liposomes; Myelodysplastic Syndromes

2021
Efficacy and safety of decitabine combined with low-dose cytarabine, aclarubicin, and granulocyte colony-stimulating factor compared with standard therapy in acute myeloid leukemia patients with TP53 mutation.
    Chinese medical journal, 2020, Dec-08, Volume: 134, Issue:12

    Topics: Aclarubicin; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Decitabine; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Mutation; Treatment Outcome; Tumor Suppressor Protein p53

2020
Polyserositis as a primary clinical manifestation of CD7+ acute myelogenous leukemia with myeloid sarcoma: A case report.
    Medicine, 2020, Dec-11, Volume: 99, Issue:50

    Topics: Adult; Antimetabolites, Antineoplastic; Cytarabine; Diagnosis, Differential; Female; Humans; Leukemia, Myeloid, Acute; Pericardial Effusion; Pleural Effusion; Positron-Emission Tomography; Sarcoma, Myeloid; Tomography, X-Ray Computed

2020
Optimal dosing of cytarabine in induction and post-remission therapy of acute myeloid leukemia.
    Leukemia, 2021, Volume: 35, Issue:2

    Topics: Antimetabolites, Antineoplastic; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid, Acute; Remission Induction

2021
Role of CD19 and specific KIT-D816 on risk stratification refinement in t(8;21) acute myeloid leukemia induced with different cytarabine intensities.
    Cancer medicine, 2021, Volume: 10, Issue:3

    Topics: Adolescent; Adult; Aged; Antigens, CD19; Antimetabolites, Antineoplastic; Biomarkers, Tumor; China; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Cytarabine; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Proto-Oncogene Proteins c-kit; Remission Induction; Retrospective Studies; Risk Assessment; Survival Rate; Translocation, Genetic; Young Adult

2021
Nrf2 overexpression increases risk of high tumor mutation burden in acute myeloid leukemia by inhibiting MSH2.
    Cell death & disease, 2021, 01-05, Volume: 12, Issue:1

    Topics: Adult; Aged; Animals; Apoptosis; Cell Line, Tumor; Cytarabine; DNA Damage; DNA Repair; Female; Heterografts; Humans; Leukemia, Myeloid, Acute; Male; Mice; Mice, Inbred NOD; Mice, SCID; Middle Aged; Mutation; MutS Homolog 2 Protein; NF-E2-Related Factor 2; THP-1 Cells; Young Adult

2021
Venetoclax-induced panniculitis in an acute myeloid leukemia patient.
    Annals of hematology, 2021, Volume: 100, Issue:5

    Topics: Allografts; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Combined Modality Therapy; Cytarabine; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Middle Aged; Panniculitis; Sulfonamides; Withholding Treatment

2021
HHV-6 encephalitis in a non-transplanted adult acute myeloid leukemia patient.
    Annals of hematology, 2021, Volume: 100, Issue:7

    Topics: Acyclovir; Adult; Antimetabolites, Antineoplastic; Antiviral Agents; Cytarabine; Encephalitis, Viral; Female; Herpesvirus 6, Human; Humans; Leukemia, Myeloid, Acute

2021
Improved outcome of children with relapsed/refractory acute myeloid leukemia by addition of cladribine to re-induction chemotherapy.
    Cancer medicine, 2021, Volume: 10, Issue:3

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cladribine; Cytarabine; Drug Resistance, Neoplasm; Etoposide; Female; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Induction Chemotherapy; Infant; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Neoplasm Recurrence, Local; Prognosis; Retrospective Studies; Salvage Therapy; Survival Rate

2021
Optimized clinical application of minimal residual disease in acute myeloid leukemia with RUNX1-RUNX1T1.
    Experimental hematology, 2021, Volume: 96

    Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Core Binding Factor Alpha 2 Subunit; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm, Residual; Oncogene Proteins, Fusion; Prognosis; RUNX1 Translocation Partner 1 Protein; Young Adult

2021
Liposomal cytarabine and daunorubicin (CPX-351/Vyxeos)-associated distinct purpuric subtype of toxic erythema of chemotherapy: A retrospective review of 54 patients.
    Journal of the American Academy of Dermatology, 2022, Volume: 86, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Erythema; Humans; Leukemia, Myeloid, Acute; Retrospective Studies

2022
Incorporation of Novel therapies for the treatment of acute myeloid leukemia: a perspective.
    Leukemia & lymphoma, 2021, Volume: 62, Issue:4

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute

2021
Intermediate dose cytarabine improves survival and relapse-free rate compared with standard-dose cytarabine as post-remission treatment for acute myeloid leukemia: A retrospection study.
    Medicine, 2021, Jan-22, Volume: 100, Issue:3

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Consolidation Chemotherapy; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Proportional Hazards Models; Remission Induction; Retrospective Studies; Survival Analysis

2021
Evaluation of Empiric Vancomycin for Fevers During High-dose Cytarabine Administration.
    Journal of pediatric hematology/oncology, 2021, Oct-01, Volume: 43, Issue:7

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Antimetabolites, Antineoplastic; Bacteremia; Burkitt Lymphoma; Child; Child, Preschool; Cytarabine; Female; Fever; Follow-Up Studies; Humans; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Lymphoma, Large B-Cell, Diffuse; Male; Prognosis; Retrospective Studies; Vancomycin; Young Adult

2021
Impact of high dose cytarabine dosing strategies in obese patients with acute myeloid leukemia.
    Leukemia research, 2021, Volume: 102

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Consolidation Chemotherapy; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Obesity; Retrospective Studies; Young Adult

2021
Real-life experience with CPX-351 and impact on the outcome of high-risk AML patients: a multicentric French cohort.
    Blood advances, 2021, 01-12, Volume: 5, Issue:1

    Topics: Adult; Aged; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Retrospective Studies

2021
Double remission of chronic lymphocytic leukemia and secondary acute myeloid leukemia after venetoclax monotherapy: A case report.
    Medicine, 2021, Feb-12, Volume: 100, Issue:6

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Daunorubicin; Disease Progression; Hematopoietic Stem Cell Transplantation; Humans; Immunophenotyping; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Leukocyte Count; Lymphocyte Count; Male; Middle Aged; Remission Induction; Sulfonamides; Treatment Outcome

2021
Recognizing the potential for copper-related toxicities from liposomal daunorubicin--cytarabine.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2021, Volume: 27, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Copper; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute

2021
Cladribine, cytarabine, and GCSF with and without mitoxantrone (CLAG ± M) is highly effective for poor risk acute myeloid leukemia with adverse karyotype and prior hypomethylating therapy.
    Leukemia & lymphoma, 2021, Volume: 62, Issue:7

    Topics: Cladribine; Cytarabine; Humans; Karyotype; Leukemia, Myeloid, Acute; Mitoxantrone

2021
Iron Oxide Nanoparticles Combined with Cytosine Arabinoside Show Anti-Leukemia Stem Cell Effects on Acute Myeloid Leukemia by Regulating Reactive Oxygen Species.
    International journal of nanomedicine, 2021, Volume: 16

    Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Separation; Cytarabine; Hemoglobins; Humans; Leukemia, Myeloid, Acute; Leukocyte Count; Magnetic Iron Oxide Nanoparticles; Mice, Inbred NOD; Mice, SCID; NADPH Oxidase 2; Neoplastic Stem Cells; Reactive Oxygen Species; Superoxide Dismutase; Xenograft Model Antitumor Assays

2021
Long noncoding RNA DANCR confers cytarabine resistance in acute myeloid leukemia by activating autophagy via the miR-874-3P/ATG16L1 axis.
    Molecular oncology, 2021, Volume: 15, Issue:4

    Topics: Apoptosis; Autophagy; Autophagy-Related Proteins; Cell Line, Tumor; Cytarabine; Drug Resistance, Neoplasm; Humans; Leukemia, Myeloid, Acute; MicroRNAs; RNA, Long Noncoding

2021
Inhibition of Autophagy Does Not Re-Sensitize Acute Myeloid Leukemia Cells Resistant to Cytarabine.
    International journal of molecular sciences, 2021, Feb-26, Volume: 22, Issue:5

    Topics: Antimetabolites, Antineoplastic; Autophagy; Cell Line, Tumor; Chloroquine; Cytarabine; Drug Resistance, Neoplasm; Humans; Leukemia, Myeloid, Acute; Tumor Cells, Cultured

2021
GLI1 reduces drug sensitivity by regulating cell cycle through PI3K/AKT/GSK3/CDK pathway in acute myeloid leukemia.
    Cell death & disease, 2021, 03-03, Volume: 12, Issue:3

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Cell Proliferation; Cyclin-Dependent Kinases; Cytarabine; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Leukemic; Glycogen Synthase Kinase 3; HEK293 Cells; Humans; Leukemia, Myeloid, Acute; Mice, Nude; Phosphatidylinositol 3-Kinase; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyridines; Pyrimidines; Signal Transduction; THP-1 Cells; Tumor Burden; U937 Cells; Xenograft Model Antitumor Assays; Zinc Finger Protein GLI1

2021
Glasdegib in combination with low-dose Cytarabine for the outpatient treatment of relapsed or refractory acute myeloid leukemia in unfit patients.
    Annals of hematology, 2021, Volume: 100, Issue:5

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Phenylurea Compounds; Retrospective Studies; Treatment Outcome

2021
AHR signaling pathway reshapes the metabolism of AML/MDS cells and potentially leads to cytarabine resistance.
    Acta biochimica et biophysica Sinica, 2021, Mar-26, Volume: 53, Issue:4

    Topics: Adult; Aged; Basic Helix-Loop-Helix Transcription Factors; Cytarabine; Drug Resistance, Neoplasm; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Neoplasm Proteins; Receptors, Aryl Hydrocarbon; Signal Transduction; THP-1 Cells; U937 Cells

2021
Outcome of secondary acute myeloid leukemia treated with hypomethylating agent plus venetoclax (HMA-Ven) or liposomal daunorubicin-cytarabine (CPX-351).
    American journal of hematology, 2021, 06-01, Volume: 96, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Combined Modality Therapy; Cytarabine; Daunorubicin; Female; Hematopoietic Stem Cell Transplantation; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Liposomes; Male; Middle Aged; Neoplasms, Second Primary; Remission Induction; Retrospective Studies; Sulfonamides; Treatment Outcome

2021
Associations between complete remission and 2- to 3-year survival following 7 + 3 induction for acute myeloid leukemia.
    Leukemia & lymphoma, 2021, Volume: 62, Issue:8

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Leukemia, Myeloid, Acute; Prognosis; Remission Induction

2021
Comparative effectiveness of glasdegib versus venetoclax combined with low-dose cytarabine in acute myeloid leukemia.
    Journal of comparative effectiveness research, 2021, Volume: 10, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Humans; Leukemia, Myeloid, Acute; Phenylurea Compounds; Sulfonamides

2021
Evaluation of the Anticancer Activity of pH-Sensitive Polyketal Nanoparticles for Acute Myeloid Leukemia.
    Molecular pharmaceutics, 2021, 05-03, Volume: 18, Issue:5

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytarabine; Drug Carriers; Female; Humans; Hydrogen-Ion Concentration; Leukemia, Myeloid, Acute; Mice; Nanoparticles; Polymers; Tissue Distribution

2021
Downregulation of MTSS1 in acute myeloid leukemia is associated with a poor prognosis, chemotherapy resistance, and disease aggressiveness.
    Leukemia, 2021, Volume: 35, Issue:10

    Topics: Animals; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cell Cycle Proteins; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Leukemic; Humans; Leukemia, Myeloid, Acute; Mice, Inbred C57BL; Microfilament Proteins; Neoplasm Proteins; Prognosis; Protein-Tyrosine Kinases; Survival Rate

2021
Minimally myelosuppressive regimen for remission induction in pediatric AML: long-term results of an observational study.
    Blood advances, 2021, 04-13, Volume: 5, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Remission Induction

2021
Development and characterization of a novel flavopiridol formulation for treatment of acute myeloid leukemia.
    Journal of controlled release : official journal of the Controlled Release Society, 2021, 05-10, Volume: 333

    Topics: Animals; Cytarabine; Flavonoids; Leukemia, Myeloid, Acute; Liposomes; Mice; Piperidines

2021
Retrospective Analysis of Adult Patients With Relapsed/Refractory Acute Myeloid Leukemia Treated with FLAG at a Comprehensive Cancer Center.
    Clinical lymphoma, myeloma & leukemia, 2021, Volume: 21, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cancer Care Facilities; Cytarabine; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Recurrence, Local; Pancytopenia; Retrospective Studies; Salvage Therapy; Survival Rate; Vidarabine; Young Adult

2021
Multicenter comparison of high-dose cytarabine-based regimens versus liposomal daunorubicin and cytarabine (CPX-351) in patients with secondary acute myeloid leukemia.
    Leukemia & lymphoma, 2021, Volume: 62, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Retrospective Studies

2021
Decitabine combined with medium-dose cytarabine in the treatment of DEK/CAN-positive acute myeloid leukemia: a case report.
    Annals of palliative medicine, 2021, Volume: 10, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chromosomal Proteins, Non-Histone; Cytarabine; Decitabine; Humans; Leukemia, Myeloid, Acute; Oncogene Proteins; Poly-ADP-Ribose Binding Proteins; Treatment Outcome

2021
Prognostic factors and their importance in relapsed and refractory AML: Comments on "Additional impact of mutational genotype on prognostic determination in resistant and relapsed acute myeloid leukaemia" by Linch et al.
    Leukemia research, 2021, Volume: 105

    Topics: Cytarabine; Genotype; Humans; Leukemia, Myeloid, Acute; Neoplasm Recurrence, Local; Prognosis

2021
Venetoclax combinations induce high response rates in newly diagnosed acute myeloid leukemia patients ineligible for intensive chemotherapy in routine practice.
    American journal of hematology, 2021, 07-01, Volume: 96, Issue:7

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Sulfonamides; Treatment Outcome

2021
Enhanced cytarabine-induced killing in OGG1-deficient acute myeloid leukemia cells.
    Proceedings of the National Academy of Sciences of the United States of America, 2021, 03-16, Volume: 118, Issue:11

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Antimetabolites, Antineoplastic; Cell Line, Tumor; Core Binding Factor Alpha 2 Subunit; Cytarabine; DNA Glycosylases; DNA Repair; Humans; Leukemia, Myeloid, Acute; RNA, Messenger

2021
Pretreatment clinical and genetic factors predict early post-treatment mortality in fit AML patients following induction.
    American journal of hematology, 2021, 07-01, Volume: 96, Issue:7

    Topics: Adult; Aged; Anthracyclines; Antineoplastic Agents; Cytarabine; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Middle Aged; Prognosis; Treatment Outcome

2021
Successful Bone Marrow Transplantation With Intensive Post-transplant Intrathecal Chemotherapy for CNS Relapsed AML in 2 Infants.
    Journal of pediatric hematology/oncology, 2022, 01-01, Volume: 44, Issue:1

    Topics: Allografts; Bone Marrow Transplantation; Central Nervous System Neoplasms; Cytarabine; Female; Humans; Infant; Injections, Spinal; Leukemia, Myeloid, Acute; Myeloablative Agonists; Recurrence; Transplantation Conditioning

2022
Efficacy and safety of consolidation therapy with intermediate and high dose cytarabine in acute myeloid leukemia patients.
    Hematology (Amsterdam, Netherlands), 2021, Volume: 26, Issue:1

    Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Consolidation Chemotherapy; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Retrospective Studies; Treatment Outcome; Young Adult

2021
Long-term results of low-intensity chemotherapy with clofarabine or cladribine combined with low-dose cytarabine alternating with decitabine in older patients with newly diagnosed acute myeloid leukemia.
    American journal of hematology, 2021, 08-01, Volume: 96, Issue:8

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Clofarabine; Cytarabine; Decitabine; Humans; Leukemia, Myeloid, Acute; Middle Aged; Nucleophosmin; Treatment Outcome

2021
Real-World Outcomes of Patients with Acute Myeloid Leukemia in Taiwan: A Nationwide Population-Based Study, 2011-2015.
    Clinical lymphoma, myeloma & leukemia, 2021, Volume: 21, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Hematopoietic Stem Cell Transplantation; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Registries; Retrospective Studies; Survival Analysis; Taiwan; Treatment Outcome

2021
Clinical Characteristics and Optimal Therapy of Acute Myeloid Leukemia with Myelodysplasia-Related Changes: A Retrospective Analysis of a Cohort of Chinese Patients
    Turkish journal of haematology : official journal of Turkish Society of Haematology, 2021, 08-25, Volume: 38, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; China; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Retrospective Studies

2021
Cytarabine-Induced Corneal Toxicity: Clinical Features and Relief of Symptoms with Loteprednol Etabonate 0.5% in Two Patients
    Turkish journal of ophthalmology, 2021, 04-29, Volume: 51, Issue:2

    Topics: Adult; Anti-Allergic Agents; Antimetabolites, Antineoplastic; Cornea; Corneal Diseases; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Loteprednol Etabonate; Male; Microscopy, Confocal; Ophthalmic Solutions

2021
Frequency of infusion-related reactions with CPX-351 treatment in an observational study in adults with newly diagnosed therapy-related AML or AML with myelodysplasia-related changes (AML-MRC).
    Leukemia & lymphoma, 2021, Volume: 62, Issue:10

    Topics: Adult; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes

2021
[A Case of Descending Colon and Rectal Cancer with Acute Myeloid Leukemia Performed Robot‒Assisted Hartmann's Procedure].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2021, Volume: 48, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colon, Descending; Cytarabine; Humans; Leukemia, Myeloid, Acute; Male; Rectal Neoplasms; Remission Induction; Robotics

2021
Zwitterion-functionalized hollow mesoporous Prussian blue nanoparticles for targeted and synergetic chemo-photothermal treatment of acute myeloid leukemia.
    Journal of materials chemistry. B, 2021, 07-07, Volume: 9, Issue:26

    Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Cell Survival; Cytarabine; Daunorubicin; Drug Delivery Systems; Drug Screening Assays, Antitumor; Ferrocyanides; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Nanoparticles; Particle Size; Photothermal Therapy; Polyethyleneimine; Porosity; Surface Properties

2021
[The Relationship between Body Mass Index and Adult Acute Myeloid Leukemia].
    Zhongguo shi yan xue ye xue za zhi, 2021, Volume: 29, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Body Mass Index; Cytarabine; Female; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Retrospective Studies; Young Adult

2021
Curcumin induces apoptosis by inhibiting BCAT1 expression and mTOR signaling in cytarabine‑resistant myeloid leukemia cells.
    Molecular medicine reports, 2021, Volume: 24, Issue:2

    Topics: Adolescent; Apoptosis; Cell Line, Tumor; Child; Curcumin; Cytarabine; Drug Resistance, Neoplasm; Female; Humans; Indoles; Ketoglutaric Acids; Leukemia, Myeloid, Acute; Male; Purines; Signal Transduction; TOR Serine-Threonine Kinases; Transaminases

2021
Inhibition of Nrf2-mediated glucose metabolism by brusatol synergistically sensitizes acute myeloid leukemia to Ara-C.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 142

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cytarabine; Drug Synergism; Female; Glucose; Glucosephosphate Dehydrogenase; Glutamate-Cysteine Ligase; Glycolysis; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Liver; Mice, Inbred BALB C; Mice, Nude; NF-E2-Related Factor 2; Quassins; THP-1 Cells; Tumor Burden; Xenograft Model Antitumor Assays

2021
Intracranial myeloid sarcoma presentation in distant acute myeloid leukemia remission.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2021, Volume: 89

    Topics: Adult; Aminopyridines; Brain Neoplasms; Cytarabine; Female; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Remission Induction; Sarcoma, Myeloid; Triazines

2021
Personalized prediction of overall survival in patients with AML in non-complete remission undergoing allo-HCT.
    Cancer medicine, 2021, Volume: 10, Issue:13

    Topics: Adult; Age Factors; Bone Marrow Transplantation; Busulfan; Cord Blood Stem Cell Transplantation; Cyclophosphamide; Cytarabine; Female; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Kaplan-Meier Estimate; Karnofsky Performance Status; Leukemia, Myeloid, Acute; Male; Melphalan; Middle Aged; Nomograms; Peripheral Blood Stem Cell Transplantation; Retrospective Studies; Transplantation Conditioning; Transplantation, Homologous; Vidarabine; Whole-Body Irradiation

2021
Thermal proteome profiling identifies PIP4K2A and ZADH2 as off-targets of Polo-like kinase 1 inhibitor volasertib.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2021, Volume: 35, Issue:7

    Topics: Antigens, Surface; Cell Cycle Proteins; Cytarabine; Fatty Acids; HL-60 Cells; Humans; Immunity; Jurkat Cells; Leukemia, Myeloid, Acute; Phosphotransferases (Alcohol Group Acceptor); Piperazines; Polo-Like Kinase 1; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proteome; Proto-Oncogene Proteins; Pteridines; Pyrazoles; Quinazolines

2021
CPX-351: an attractive option for the treatment of older patients with high-risk or secondary acute myeloid leukaemia.
    The Lancet. Haematology, 2021, Volume: 8, Issue:7

    Topics: Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Neoplasms, Second Primary

2021
Venetoclax-based salvage therapy followed by Venetoclax and DLI maintenance vs. FLAG-Ida for relapsed or refractory acute myeloid leukemia after allogeneic stem cell transplantation.
    Bone marrow transplantation, 2021, Volume: 56, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Leukemia, Myeloid, Acute; Remission Induction; Retrospective Studies; Salvage Therapy; Sulfonamides; Vidarabine

2021
Impact of induction chemotherapy with intermediate-dosed cytarabine and subsequent allogeneic stem cell transplantation on the outcome of high-risk acute myeloid leukemia.
    Journal of cancer research and clinical oncology, 2022, Volume: 148, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Hematopoietic Stem Cell Transplantation; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Middle Aged; Prognosis; Remission Induction; Retrospective Studies

2022
Second Transplant for Relapsed AML, Learning from Defeat.
    Transplantation and cellular therapy, 2021, Volume: 27, Issue:8

    Topics: Cytarabine; Humans; Leukemia, Myeloid, Acute; Neoplasm Recurrence, Local

2021
Ten-day decitabine with venetoclax versus intensive chemotherapy in relapsed or refractory acute myeloid leukemia: A propensity score-matched analysis.
    Cancer, 2021, 11-15, Volume: 127, Issue:22

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Decitabine; Humans; Leukemia, Myeloid, Acute; Propensity Score; Sulfonamides

2021
[Lineage switch from T-lymphoblastic leukemia to myeloid leukemia at relapse].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2021, Volume: 62, Issue:7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Recurrence

2021
Measurable residual disease including AML leukemia stem cell flow evaluation of CPX-351 therapy by multi-parameter flow cytometry.
    Leukemia research, 2021, Volume: 111

    Topics: Adult; Aged; Biomarkers, Tumor; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm, Residual; Neoplastic Stem Cells; Prognosis; Retrospective Studies; Young Adult

2021
RSPO2 inhibits BMP signaling to promote self-renewal in acute myeloid leukemia.
    Cell reports, 2021, 08-17, Volume: 36, Issue:7

    Topics: Animals; Autocrine Communication; Bone Morphogenetic Proteins; Cell Differentiation; Cell Self Renewal; Cytarabine; HEK293 Cells; Hematopoietic Stem Cells; Humans; Intercellular Signaling Peptides and Proteins; Leukemia, Myeloid, Acute; Mice; Neoplastic Stem Cells; Prognosis; Risk Factors; Signal Transduction; Survival Analysis; Xenograft Model Antitumor Assays

2021
Venetoclax in combination with low dose Cytarabine and Actinomycin D for primary refractory acute myeloid leukemia patients failing intensive chemotherapy.
    Leukemia research, 2021, Volume: 111

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Dactinomycin; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Retrospective Studies; Salvage Therapy; Sulfonamides; Survival Rate

2021
Xeroderma pigmentosum and acute myeloid leukemia: a case report.
    Journal of medical case reports, 2021, Aug-26, Volume: 15, Issue:1

    Topics: Adult; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Skin Neoplasms; Xeroderma Pigmentosum

2021
A New Style of Transplantation May Gain Points When Treating Older Patients with Acute Myeloid Leukemia.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2017, Volume: 23, Issue:5

    Topics: Aged; Cytarabine; Decitabine; HLA Antigens; Humans; Leukemia, Myeloid, Acute; Stem Cells

2017
Outcome of Lower-Risk Patients With Myelodysplastic Syndromes Without 5q Deletion After Failure of Erythropoiesis-Stimulating Agents.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, May-10, Volume: 35, Issue:14

    Topics: Aged; Aged, 80 and over; Anemia; Antilymphocyte Serum; Antineoplastic Agents; Arsenic; Azacitidine; Chromosome Deletion; Chromosomes, Human, Pair 5; Cyclosporine; Cytarabine; Decitabine; Disease Progression; Enzyme Inhibitors; Erythrocyte Transfusion; Female; Hematinics; Humans; Hydroxyurea; Immunologic Factors; Lenalidomide; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Recurrence; Retreatment; Retrospective Studies; Risk Factors; Survival Rate; Thalidomide; Treatment Failure; Tretinoin; Valproic Acid

2017
FLT3 Mutation Testing in Acute Myeloid Leukemia.
    JAMA oncology, 2017, 07-01, Volume: 3, Issue:7

    Topics: Cytarabine; Daunorubicin; fms-Like Tyrosine Kinase 3; Genetic Testing; Headache; Humans; Leukapheresis; Leukemia, Myeloid, Acute; Leukostasis; Male; Middle Aged; Segmental Duplications, Genomic; Tandem Repeat Sequences; Vision Disorders

2017
A three-dimensional
    Haematologica, 2017, Volume: 102, Issue:7

    Topics: Benzylamines; Biomarkers; Cell Communication; Cell Culture Techniques; Cell Line, Tumor; Cell Movement; Cyclams; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Drug Synergism; Heterocyclic Compounds; Humans; Immunophenotyping; Leukemia, Myeloid, Acute; Neovascularization, Pathologic; Receptors, CXCR4; Spheroids, Cellular; Tumor Cells, Cultured; Tumor Microenvironment

2017
Characteristics and outcomes of older patients with secondary acute myeloid leukemia according to treatment approach.
    Cancer, 2017, Aug-15, Volume: 123, Issue:16

    Topics: Aged; Antineoplastic Agents; Azacitidine; Cytarabine; Decitabine; Female; Humans; Karyotype; Leukemia, Myeloid, Acute; Logistic Models; Male; Middle Aged; Multivariate Analysis; Neoplasms, Second Primary; Proportional Hazards Models; Remission Induction; Retrospective Studies; Treatment Outcome

2017
Marked hypereosinophilia and rash as initial presentation of acute myeloid leukemia with t(8;21).
    International journal of hematology, 2017, Volume: 106, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Cytarabine; Diagnosis, Differential; Eosinophilia; Eosinophils; Exanthema; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Molecular Diagnostic Techniques; Skin; Translocation, Genetic; Treatment Outcome; Young Adult

2017
DNA Methyltransferases Demonstrate Reduced Activity against Arabinosylcytosine: Implications for Epigenetic Instability in Acute Myeloid Leukemia.
    Biochemistry, 2017, 04-25, Volume: 56, Issue:16

    Topics: Antimetabolites, Antineoplastic; Cytarabine; DNA Modification Methylases; Epigenesis, Genetic; Humans; Leukemia, Myeloid, Acute

2017
Using low-dose homoharringtonine and cytarabine in combination with granulocyte colony-stimulating factor in a priming induction therapy for acute myeloid leukemia: a retrospective study of 29 cases in china.
    Leukemia & lymphoma, 2017, Volume: 58, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; China; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Harringtonines; Hematopoietic Stem Cell Transplantation; Homoharringtonine; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Retrospective Studies; Transplantation, Homologous

2017
Cell-based evaluation of changes in coagulation activity induced by antineoplastic drugs for the treatment of acute myeloid leukemia.
    PloS one, 2017, Volume: 12, Issue:4

    Topics: Antineoplastic Agents; Benzoates; Cell Line, Tumor; Cytarabine; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Idarubicin; Leukemia, Myeloid, Acute; Phosphatidylserines; Tetrahydronaphthalenes; Thrombomodulin; Thromboplastin

2017
Escalated anthracycline dose in adult AML.
    The Lancet. Oncology, 2017, Volume: 18, Issue:5

    Topics: Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase III as Topic; Cytarabine; Disease Progression; Disease-Free Survival; Etoposide; Humans; Idarubicin; Leukemia, Myeloid, Acute; Randomized Controlled Trials as Topic; Time Factors; Treatment Outcome

2017
Chemotherapy-Resistant Human Acute Myeloid Leukemia Cells Are Not Enriched for Leukemic Stem Cells but Require Oxidative Metabolism.
    Cancer discovery, 2017, Volume: 7, Issue:7

    Topics: Animals; CD36 Antigens; Cell Line, Tumor; Cell Lineage; Cytarabine; Drug Resistance, Neoplasm; Humans; Leukemia, Myeloid, Acute; Mice; Mitochondria; Neoplastic Stem Cells; Oxidative Phosphorylation; Xenograft Model Antitumor Assays

2017
Proteasome inhibition enhances the efficacy of volasertib-induced mitotic arrest in AML in vitro and prolongs survival in vivo.
    Oncotarget, 2017, Mar-28, Volume: 8, Issue:13

    Topics: Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Bortezomib; Cell Cycle Proteins; Cell Line, Tumor; Cyclin B; Cytarabine; Frail Elderly; Humans; Leukemia, Myeloid, Acute; Mice; Mice, Inbred NOD; Mitosis; Polo-Like Kinase 1; Proteasome Inhibitors; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Pteridines; Treatment Outcome; Xenograft Model Antitumor Assays

2017
Chidamide in FLT3-ITD positive acute myeloid leukemia and the synergistic effect in combination with cytarabine.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 90

    Topics: Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Differentiation; Cell Line, Tumor; Cytarabine; Drug Synergism; fms-Like Tyrosine Kinase 3; G1 Phase; Histone Deacetylase Inhibitors; Humans; Leukemia, Myeloid, Acute; Lymphoma, T-Cell; Mutation; Resting Phase, Cell Cycle; Signal Transduction

2017
Successful Management of Decitabine prior to Full-Dose Idarubicin and Cytarabine in the Treatment of Refractory/Recurrent Acute Myeloid Leukemia.
    Acta haematologica, 2017, Volume: 137, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Combined Modality Therapy; Cytarabine; Decitabine; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Remission Induction; Retrospective Studies; Stem Cell Transplantation; Transplantation, Homologous

2017
[Efficacy Comparison of Different Salvage Treatment Regimens for Patients with Refractory/Relapsed Acute Myeloid Leukemia].
    Zhongguo shi yan xue ye xue za zhi, 2017, Volume: 25, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Remission Induction; Retrospective Studies; Salvage Therapy; Treatment Outcome

2017
A life-threatening ruxolitinib discontinuation syndrome.
    American journal of hematology, 2017, Volume: 92, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Diagnosis, Differential; Disease Progression; Dose-Response Relationship, Drug; Female; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Janus Kinase 2; Leukemia, Myeloid, Acute; Middle Aged; Nitriles; Pneumonia; Protein Kinase Inhibitors; Pulmonary Embolism; Pyrazoles; Pyrimidines; Remission Induction; Respiratory Distress Syndrome; Substance Withdrawal Syndrome; Thrombocythemia, Essential; Tomography, X-Ray Computed

2017
[Long-term safety and efficacy of high-dose cytarabine consolidation in patients with acute myeloid leukemia].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2017, Apr-14, Volume: 38, Issue:4

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Leukemia, Myeloid, Acute; Remission Induction

2017
Bioinformatic analysis of the effects and mechanisms of decitabine and cytarabine on acute myeloid leukemia.
    Molecular medicine reports, 2017, Volume: 16, Issue:1

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Computational Biology; Cytarabine; Databases, Genetic; Decitabine; DNA Methylation; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Gene Ontology; Gene Regulatory Networks; Humans; Leukemia, Myeloid, Acute; Molecular Sequence Annotation

2017
Role of NF-E2 related factor 2 (Nrf2) on chemotherapy resistance in acute myeloid leukemia (AML) and the effect of pharmacological inhibition of Nrf2.
    PloS one, 2017, Volume: 12, Issue:5

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Cell Line, Tumor; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Gene Expression; Gene Knockdown Techniques; Humans; Inhibitory Concentration 50; Kelch-Like ECH-Associated Protein 1; Leukemia, Myeloid, Acute; Mutation; NF-E2-Related Factor 2; Protein Transport; Response Elements; Tumor Cells, Cultured

2017
Relationship between white blood cell count elevation and clinical response after G-CSF priming chemotherapy for acute myeloid leukemia.
    International journal of hematology, 2017, Volume: 106, Issue:3

    Topics: Aclarubicin; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Remission Induction; Retrospective Studies; Young Adult

2017
Ultrasonography-driven combination antibiotic therapy with tigecycline significantly increases survival among patients with neutropenic enterocolitis following cytarabine-containing chemotherapy for the remission induction of acute myeloid leukemia.
    Cancer medicine, 2017, Volume: 6, Issue:7

    Topics: Adult; Aged; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease Management; Drug Therapy, Combination; Enterocolitis, Neutropenic; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Minocycline; Mortality; Remission Induction; Tigecycline; Treatment Outcome; Ultrasonography; Workflow; Young Adult

2017
Impact of novel polymorphisms related to cytotoxicity of cytarabine in the induction treatment of acute myeloid leukemia.
    Pharmacogenetics and genomics, 2017, Volume: 27, Issue:7

    Topics: Adolescent; Adult; Aged; Cytarabine; Disease-Free Survival; Humans; Induction Chemotherapy; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Middle Aged; Polymorphism, Single Nucleotide; Young Adult

2017
Influence of cytarabine metabolic pathway polymorphisms in acute myeloid leukemia induction treatment.
    Leukemia & lymphoma, 2017, Volume: 58, Issue:12

    Topics: Adolescent; Adult; Aged; Alleles; Antimetabolites, Antineoplastic; Cytarabine; Female; Genotype; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Metabolic Networks and Pathways; Middle Aged; Pharmacogenomic Variants; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Prognosis; Remission Induction; Retrospective Studies; Young Adult

2017
Looking up for AML in Down syndrome.
    Blood, 2017, 06-22, Volume: 129, Issue:25

    Topics: Cytarabine; Down Syndrome; Etoposide; Humans; Leukemia, Myeloid, Acute

2017
Autophagy is an important event for low-dose cytarabine treatment in acute myeloid leukemia cells.
    Leukemia research, 2017, Volume: 60

    Topics: Autophagy; Cell Death; Cell Differentiation; Cell Line, Tumor; Cytarabine; Dose-Response Relationship, Drug; HeLa Cells; Humans; Leukemia, Myeloid, Acute; Metabolic Networks and Pathways; Oncogene Protein v-akt; Time Factors; TOR Serine-Threonine Kinases; U937 Cells

2017
Novel Mitochondrial Mechanisms of Cytarabine Resistance in Primary AML Cells.
    Cancer discovery, 2017, Volume: 7, Issue:7

    Topics: Animals; Bone Marrow Cells; Cytarabine; Drug Resistance, Neoplasm; Humans; Leukemia, Myeloid, Acute; Mice; Mitochondria; Oxidative Phosphorylation

2017
Release of Danger-Associated Molecular Patterns following Chemotherapy Does Not Induce Immunoparalysis in Leukemia Patients.
    Acta haematologica, 2017, Volume: 138, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Biomarkers; Case-Control Studies; Cells, Cultured; Cholesterol, LDL; Cytarabine; Cytokines; DNA; DNA, Mitochondrial; Female; HLA-DR Antigens; Humans; Idarubicin; Leukemia; Leukemia, Myeloid, Acute; Leukocytes; Lipopolysaccharides; Male; Middle Aged; Myelodysplastic Syndromes; Young Adult

2017
JNK1 as a signaling node in VDR-BRAF induction of cell death in AML.
    The Journal of steroid biochemistry and molecular biology, 2018, Volume: 177

    Topics: Antimetabolites, Antineoplastic; Cell Death; Cytarabine; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Proto-Oncogene Proteins B-raf; Receptors, Calcitriol; RNA, Messenger; RNA, Small Interfering; Signal Transduction

2018
Unexpected diagnosis of appendicitis in a paediatric patient with febrile neutropaenia and acute myeloid leukaemia.
    BMJ case reports, 2017, Aug-07, Volume: 2017

    Topics: Antineoplastic Combined Chemotherapy Protocols; Appendicitis; Child, Preschool; Cytarabine; Daunorubicin; Etoposide; Febrile Neutropenia; Humans; Incidental Findings; Leukemia, Myeloid, Acute; Male; Tomography, X-Ray Computed

2017
JSH guideline for tumors of hematopoietic and lymphoid tissues: leukemia 1. Acute myeloid leukemia (AML).
    International journal of hematology, 2017, Volume: 106, Issue:3

    Topics: Age Factors; Aged; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Genetic Therapy; Hematology; Hematopoietic Stem Cell Transplantation; Humans; Induction Chemotherapy; Japan; Leukemia, Myeloid, Acute; Male; Middle Aged; Practice Guidelines as Topic; Prognosis; Societies, Medical

2017
Acute myeloid leukaemia masquerading as a primary CNS tumour.
    BMJ case reports, 2017, Aug-11, Volume: 2017

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Central Nervous System Neoplasms; Child, Preschool; Cytarabine; Daunorubicin; Etoposide; fms-Like Tyrosine Kinase 3; Humans; In Situ Hybridization, Fluorescence; Leukemia, Myeloid, Acute; Magnetic Resonance Imaging; Male; Sarcoma, Myeloid; Treatment Outcome

2017
Cooperative effect of chidamide and chemotherapeutic drugs induce apoptosis by DNA damage accumulation and repair defects in acute myeloid leukemia stem and progenitor cells.
    Clinical epigenetics, 2017, Volume: 9

    Topics: Adolescent; Adult; Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytarabine; Daunorubicin; DNA Damage; DNA Repair; Drug Therapy; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Neoplastic Stem Cells; Young Adult

2017
Systemic mastocytosis associated with acute myeloid leukaemia.
    Pathology, 2017, Volume: 49, Issue:6

    Topics: Adult; Biopsy, Needle; Bone Marrow; Cytarabine; Humans; Idarubicin; Immunohistochemistry; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Mastocytosis, Systemic; Proto-Oncogene Proteins c-kit

2017
Therapy-related acute myeloid leukemia with inv(16) after successful therapy for de novo acute myeloid leukemia with t(8;21).
    Annals of hematology, 2017, Volume: 96, Issue:12

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; CCAAT-Binding Factor; Chromosome Inversion; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Combined Modality Therapy; Core Binding Factor Alpha 2 Subunit; Cytarabine; Female; Humans; Idarubicin; In Situ Hybridization, Fluorescence; Leukemia, Myeloid, Acute; Myosin Heavy Chains; Neoplasms, Second Primary; Oncogene Proteins, Fusion; Peripheral Blood Stem Cell Transplantation; Reverse Transcriptase Polymerase Chain Reaction; RUNX1 Translocation Partner 1 Protein; Translocation, Genetic; Transplantation, Autologous

2017
FLAG-Ida Regimen as Bridge Therapy to Allotransplantation in Refractory/Relapsed Acute Myeloid Leukemia Patients.
    Clinical lymphoma, myeloma & leukemia, 2017, Volume: 17, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Recurrence; Survival Analysis; Vascularized Composite Allotransplantation; Vidarabine

2017
A case report of acute myelogenous leukemia with Turner Syndrome.
    JPMA. The Journal of the Pakistan Medical Association, 2017, Volume: 67, Issue:9

    Topics: Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bone Marrow; Cytarabine; Daunorubicin; Female; Humans; Incidental Findings; Karyotype; Karyotyping; Leukemia, Myeloid, Acute; Middle Aged; Turner Syndrome

2017
Consolidation therapy with decitabine and intermediate-dose cytarabine followed by HLA-mismatched peripheral blood stem cells infusion for older patients with acute myeloid leukemia in first remission.
    Leukemia & lymphoma, 2018, Volume: 59, Issue:7

    Topics: Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Consolidation Chemotherapy; Cytarabine; Decitabine; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Histocompatibility Testing; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm, Residual; Remission Induction; Survival Analysis; Transplantation Chimera; Transplantation, Homologous; Treatment Outcome; Unrelated Donors

2018
ABCG2 overexpression and deoxyadenosine analogue activity in acute myeloid leukemia.
    Cancer, 2017, 12-15, Volume: 123, Issue:24

    Topics: ATP Binding Cassette Transporter, Subfamily G, Member 2; Clofarabine; Cytarabine; Deoxyadenosines; Humans; Idarubicin; Leukemia, Myeloid, Acute; Neoplasm Proteins; Vidarabine

2017
Pericarditis associated with cytarabine therapy for acute myelocytic leukemia: a case report.
    European journal of clinical pharmacology, 2018, Volume: 74, Issue:2

    Topics: Adult; Antimetabolites, Antineoplastic; Cytarabine; Humans; Leukemia, Myeloid, Acute; Male; Pericarditis

2018
Efficacy of CLARA in recurrent/refractory acute myeloid leukaemia patients unresponsive to FLAG chemotherapy.
    Journal of chemotherapy (Florence, Italy), 2018, Volume: 30, Issue:1

    Topics: Adenine Nucleotides; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cytarabine; Drug Resistance, Neoplasm; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Recurrence, Local; Retrospective Studies; Salvage Therapy; Vidarabine; Young Adult

2018
Towards repositioning of quinacrine for treatment of acute myeloid leukemia - Promising synergies and in vivo effects.
    Leukemia research, 2017, Volume: 63

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Proliferation; Cytarabine; Drug Repositioning; Drug Synergism; Female; Humans; Leukemia, Myeloid, Acute; Male; Mice; Mice, SCID; Middle Aged; Quinacrine; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2017
N6L pseudopeptide interferes with nucleophosmin protein-protein interactions and sensitizes leukemic cells to chemotherapy.
    Cancer letters, 2018, 01-01, Volume: 412

    Topics: Cell Line, Tumor; Cytarabine; Doxorubicin; Humans; Leukemia, Myeloid, Acute; Mutation; Nuclear Proteins; Nucleophosmin; Peptides; Tumor Suppressor Protein p53

2018
TGF-β1 and CXCL12 modulate proliferation and chemotherapy sensitivity of acute myeloid leukemia cells co-cultured with multipotent mesenchymal stromal cells.
    Hematology (Amsterdam, Netherlands), 2018, Volume: 23, Issue:6

    Topics: Adult; Aged; Animals; Antimetabolites, Antineoplastic; Biomarkers; Bone Marrow; Bone Marrow Cells; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Chemokine CXCL12; Chromosome Aberrations; Coculture Techniques; Cytarabine; Drug Resistance, Neoplasm; Female; Humans; Immunophenotyping; Leukemia, Myeloid, Acute; Male; Mesenchymal Stem Cells; Mice; Middle Aged; Neoplasm Grading; Transforming Growth Factor beta1

2018
Polymorphisms at microRNA binding sites of Ara-C and anthracyclines-metabolic pathway genes are associated with outcome of acute myeloid leukemia patients.
    Journal of translational medicine, 2017, Nov-15, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Aged; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Binding Sites; Biomarkers, Tumor; Cytarabine; Female; Follow-Up Studies; Genetic Predisposition to Disease; Humans; Inactivation, Metabolic; Leukemia, Myeloid, Acute; Male; Metabolic Networks and Pathways; MicroRNAs; Middle Aged; Polymorphism, Single Nucleotide; Prognosis; Remission Induction; Survival Analysis; Treatment Outcome; Young Adult

2017
The combination of CHK1 inhibitor with G-CSF overrides cytarabine resistance in human acute myeloid leukemia.
    Nature communications, 2017, 11-22, Volume: 8, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Checkpoint Kinase 1; Cytarabine; Drug Resistance, Neoplasm; Female; Granulocyte Colony-Stimulating Factor; Hematopoiesis; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Male; Mice; Mice, Inbred NOD; Mice, SCID; Mutation; Piperidines; Protein Kinase Inhibitors; Pyridines; Pyrroles; U937 Cells; Xenograft Model Antitumor Assays

2017
Anthracycline-induced acute myocarditis and ventricular fibrillation arrest.
    American journal of hematology, 2018, Volume: 93, Issue:3

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Cardiopulmonary Resuscitation; Chest Pain; Combined Modality Therapy; Cytarabine; Defibrillators, Implantable; Echocardiography; Etoposide; Heart Arrest; Humans; Idarubicin; Leukemia, Myeloid, Acute; Magnetic Resonance Imaging; Male; Middle Aged; Myocarditis; Ventricular Fibrillation

2018
Evaluating the Impact of the Addition of Cladribine to Standard Acute Myeloid Leukemia Induction Therapy.
    The Annals of pharmacotherapy, 2018, Volume: 52, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cohort Studies; Cytarabine; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Middle Aged; Propensity Score; Remission Induction; Retrospective Studies; Treatment Outcome

2018
[Curative Effect of Decitabine Combined with IAG Regimen for Senile Patients with Myelodysplastic Syndrome (MDS) Transformed Acute Myeloid Leukemia].
    Zhongguo shi yan xue ye xue za zhi, 2017, Volume: 25, Issue:6

    Topics: Alzheimer Disease; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Decitabine; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Treatment Outcome

2017
Outcomes of previously untreated elderly patients with AML: a propensity score-matched comparison of clofarabine vs. FLAG.
    Annals of hematology, 2018, Volume: 97, Issue:4

    Topics: Adenine Nucleotides; Aged; Aged, 80 and over; Aging; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Case-Control Studies; Chemical and Drug Induced Liver Injury; Clofarabine; Cohort Studies; Combined Modality Therapy; Cost Savings; Costs and Cost Analysis; Cytarabine; Granulocyte Colony-Stimulating Factor; Hospital Costs; Humans; Incidence; Induction Chemotherapy; Length of Stay; Leukemia, Myeloid, Acute; Michigan; Middle Aged; Neutropenia; Propensity Score; Retrospective Studies; Survival Analysis; Tertiary Care Centers; Vidarabine

2018
Evolution of Cytogenetically Normal Acute Myeloid Leukemia During Therapy and Relapse: An Exome Sequencing Study of 50 Patients.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2018, 04-01, Volume: 24, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Cell Line; Cytarabine; Cytogenetics; DNA (Cytosine-5-)-Methyltransferases; Drug Resistance; Epigenesis, Genetic; Exome; Exome Sequencing; Female; Histone Demethylases; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Recurrence; Remission Induction; Young Adult

2018
Early minimal residual disease assessment after AML induction with fludarabine, cytarabine and idarubicin (FLAI) provides the most useful prognostic information.
    British journal of haematology, 2019, Volume: 184, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm, Residual; Survival Rate; Vidarabine

2019
Acute myeloid leukemia presenting as erythema nodosum: A case report.
    Medicine, 2017, Volume: 96, Issue:47

    Topics: Antineoplastic Agents; Bone Marrow Examination; Cytarabine; Daunorubicin; Erythema Nodosum; Fatal Outcome; Female; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Middle Aged; Recurrence; Remission Induction

2017
[Clinical Efficacy of Decitabine Combined with or without Cytarabine-based Low Dose Regimen for Senile patients with Acute Myeloid Leukemia].
    Zhongguo shi yan xue ye xue za zhi, 2018, Volume: 26, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Decitabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Remission Induction; Retrospective Studies; Treatment Outcome

2018
A real-world study of clofarabine and cytarabine combination therapy for patients with acute myeloid leukemia.
    Leukemia & lymphoma, 2018, Volume: 59, Issue:10

    Topics: Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Clofarabine; Cytarabine; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Minnesota; Progression-Free Survival; Remission Induction; Retrospective Studies; Salvage Therapy

2018
Ara-C ears: an actual drug-induced reaction or a distinctive manifestation of a neutrophilic dermatosis?
    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2018, Volume: 16, Issue:2

    Topics: Adult; Biopsy; Cytarabine; Drug Therapy, Combination; Ear Diseases; Ear, External; Erythema; Follow-Up Studies; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Sweet Syndrome

2018
Effect of NPM1 type B mutation on the proliferation, invasion and chemosensitivity of THP-1 leukemia cells.
    Die Pharmazie, 2017, Oct-01, Volume: 72, Issue:10

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cytarabine; Humans; Leukemia, Myeloid, Acute; Mutation; Neoplasm Invasiveness; Nuclear Proteins; Nucleophosmin; Prognosis

2017
Can we forecast induction failure in acute myeloid leukemia?
    Haematologica, 2018, Volume: 103, Issue:3

    Topics: Cytarabine; Cytogenetics; Humans; Leukemia, Myeloid, Acute

2018
AML refractory to primary induction with Ida-FLAG has a poor clinical outcome.
    Leukemia research, 2018, Volume: 68

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Genes, p53; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Prognosis; Remission Induction; Retrospective Studies; Treatment Outcome; Vidarabine; Young Adult

2018
High transplant-related mortality associated with haematopoietic stem cell transplantation for paediatric therapy-related acute myeloid leukaemia (t-AML). A study on behalf of the United Kingdom Paediatric Blood and Bone Marrow Transplant Group.
    Bone marrow transplantation, 2018, Volume: 53, Issue:9

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Neoplasms, Second Primary; Remission Induction; Salvage Therapy; Survival Analysis; United Kingdom; Vidarabine

2018
Consolidation Chemotherapy Prevents Relapse by Indirectly Regulating Bone Marrow Adipogenesis in Patients with Acute Myeloid Leukemia.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 45, Issue:6

    Topics: Adipocytes; Adipogenesis; Adult; Aged; Antimetabolites, Antineoplastic; Bone Marrow; Cells, Cultured; Consolidation Chemotherapy; Cytarabine; Female; Growth Differentiation Factor 15; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Retrospective Studies; Secondary Prevention

2018
Successes and challenges in the treatment of pediatric acute myeloid leukemia: a retrospective analysis of the AML-BFM trials from 1987 to 2012.
    Leukemia, 2018, Volume: 32, Issue:10

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Disease-Free Survival; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Recurrence; Retrospective Studies; Salvage Therapy; Treatment Outcome

2018
Major response of PNH to an AML chemotherapy protocol.
    Annals of hematology, 2018, Volume: 97, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Blast Crisis; Cytarabine; Daunorubicin; Hemoglobinuria, Paroxysmal; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction

2018
CXCR4-mediated signaling regulates autophagy and influences acute myeloid leukemia cell survival and drug resistance.
    Cancer letters, 2018, 07-01, Volume: 425

    Topics: Adult; Aged; Animals; Autophagy; Cell Line, Tumor; Cell Survival; Chemokine CXCL12; Cytarabine; Drug Resistance, Neoplasm; Female; Humans; Leukemia, Myeloid, Acute; Male; Mice; Middle Aged; Neoplasm Transplantation; Receptors, CXCR4; Signal Transduction; Sirtuin 1

2018
Acute myeloid leukemia induction with cladribine: Outcomes by age and leukemia risk.
    Leukemia research, 2018, Volume: 68

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cytarabine; Female; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Proportional Hazards Models; Remission Induction; Retrospective Studies; Risk; Survival Analysis; Treatment Outcome; Young Adult

2018
Dual inhibition of PI3K/mTOR signaling in chemoresistant AML primary cells.
    Advances in biological regulation, 2018, Volume: 68

    Topics: Cell Survival; Cells, Cultured; Cytarabine; Etoposide; Humans; Leukemia, Myeloid, Acute; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; TOR Serine-Threonine Kinases

2018
Therapeutic potential of GSK-J4, a histone demethylase KDM6B/JMJD3 inhibitor, for acute myeloid leukemia.
    Journal of cancer research and clinical oncology, 2018, Volume: 144, Issue:6

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzazepines; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cytarabine; Drug Synergism; Enzyme Inhibitors; Female; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Leukemia, Myeloid, Acute; Mice; Mice, Inbred NOD; Molecular Targeted Therapy; Pyrimidines; RNA, Messenger; Up-Regulation; Xenograft Model Antitumor Assays

2018
Measurable Residual Disease at Induction Redefines Partial Response in Acute Myeloid Leukemia and Stratifies Outcomes in Patients at Standard Risk Without NPM1 Mutations.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2018, 05-20, Volume: 36, Issue:15

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Flow Cytometry; Hematopoietic Stem Cell Transplantation; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Neoplasm, Residual; Nuclear Proteins; Nucleophosmin; Prospective Studies; Risk Factors; Survival Rate; Treatment Outcome

2018
Decitabine in combination with G-CSF, low-dose cytarabine and aclarubicin is as effective as standard dose chemotherapy in the induction treatment for patients aged from 55 to 69 years old with newly diagnosed acute myeloid leukemia.
    Leukemia & lymphoma, 2018, Volume: 59, Issue:11

    Topics: Aclarubicin; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Decitabine; Female; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Remission Induction; Retrospective Studies; Survival Rate

2018
Association of genetic polymorphisms in genes involved in Ara-C and dNTP metabolism pathway with chemosensitivity and prognosis of adult acute myeloid leukemia (AML).
    Journal of translational medicine, 2018, 04-10, Volume: 16, Issue:1

    Topics: Adolescent; Adult; Aged; Cytarabine; Disease-Free Survival; Female; Gene Expression Regulation, Leukemic; Genetic Association Studies; Genetic Predisposition to Disease; Humans; Leukemia, Myeloid, Acute; Logistic Models; Male; Middle Aged; Multivariate Analysis; Neoplasm Proteins; Nucleotides; Polymorphism, Single Nucleotide; Prognosis; Proportional Hazards Models; Quantitative Trait Loci; Remission Induction; Young Adult

2018
In brief: Two new drugs for AML.
    The Medical letter on drugs and therapeutics, 2018, 03-26, Volume: 60, Issue:1543

    Topics: Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Enzyme Inhibitors; Humans; Isocitrate Dehydrogenase; Leukemia, Myeloid, Acute; Liposomes; Mutation; Treatment Outcome; Triazines

2018
Acute Onset Unilateral Proptosis.
    The American journal of medicine, 2018, Volume: 131, Issue:8

    Topics: Aged; Antineoplastic Agents; Cytarabine; Exophthalmos; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Radiotherapy; Sarcoma, Myeloid

2018
[Complete Remission Rate and Adverse Ractions of Three Different Chemotherapy Regimens in the Treatment of Adult Patients with Newly Diagnosed Non-M3 AML].
    Zhongguo shi yan xue ye xue za zhi, 2018, Volume: 26, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Idarubicin; Leukemia, Myeloid, Acute; Remission Induction

2018
Epigenetic Therapy in a Patient With Down Syndrome and Refractory Acute Myeloid Leukemia.
    Journal of pediatric hematology/oncology, 2019, Volume: 41, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Decitabine; Down Syndrome; Granulocyte Colony-Stimulating Factor; Humans; Infant; Leukemia, Myeloid, Acute; Male; Vidarabine; Vorinostat

2019
An Integrated Genome-wide CRISPRa Approach to Functionalize lncRNAs in Drug Resistance.
    Cell, 2018, 04-19, Volume: 173, Issue:3

    Topics: Animals; CRISPR-Cas Systems; Cytarabine; Drug Resistance, Neoplasm; Female; Gene Expression Profiling; Gene Regulatory Networks; Genome, Human; HEK293 Cells; HL-60 Cells; Humans; K562 Cells; Leukemia, Myeloid, Acute; Male; Mice; Pharmacogenetics; Proteins; RNA; RNA, Long Noncoding; RNA, Messenger; Signal Transduction

2018
Genital ulcers as diagnostic clue for acute myeloid leukaemia.
    International wound journal, 2018, Volume: 15, Issue:5

    Topics: Adult; Antibiotics, Antineoplastic; Antineoplastic Agents; Cytarabine; Daunorubicin; Female; Fissure in Ano; Genitalia; Gingival Hyperplasia; Humans; Leukemia, Myeloid, Acute; Treatment Outcome; Young Adult

2018
Clearance of Somatic Mutations at Remission and the Risk of Relapse in Acute Myeloid Leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2018, 06-20, Volume: 36, Issue:18

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase II as Topic; Clofarabine; Cohort Studies; Cytarabine; DNA, Neoplasm; Female; High-Throughput Nucleotide Sequencing; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Recurrence; Sequence Analysis, DNA; Vidarabine

2018
A new intensive conditioning regimen for allogeneic hematopoietic stem cell transplantation in patients with refractory or relapsed acute myeloid leukemia.
    Medicine, 2018, Volume: 97, Issue:17

    Topics: Adolescent; Adult; Busulfan; Cyclophosphamide; Cystitis; Cytarabine; Cytomegalovirus Infections; Drug Therapy, Combination; Epstein-Barr Virus Infections; Female; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Leukocytes; Male; Prospective Studies; Transplantation Conditioning; Young Adult

2018
Connecting the Dots: A Case of Myeloid Sarcoma.
    The American journal of medicine, 2018, Volume: 131, Issue:9

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bone Marrow; Cladribine; Cytarabine; Fatal Outcome; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Sarcoma, Myeloid

2018
Characteristics of adult patients treated for acute myeloid leukemia with inv 16 in Casablanca (Morocco).
    Bulletin du cancer, 2018, Volume: 105, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cause of Death; Chromosome Inversion; Chromosomes, Human, Pair 16; Core Binding Factor beta Subunit; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Leukocytosis; Longitudinal Studies; Male; Middle Aged; Morocco; Myosin Heavy Chains; Oncogene Proteins, Fusion; Prognosis; Young Adult

2018
[Comparison of the efficacy of decitabine combined with micro-transplantation or priming regimen as consolidation treatment for older patients with acute myeloid leukemia].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2018, Apr-14, Volume: 39, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Consolidation Chemotherapy; Cytarabine; Decitabine; Humans; Leukemia, Myeloid, Acute; Middle Aged; Treatment Outcome

2018
Venetoclax and low-dose cytarabine induced complete remission in a patient with high-risk acute myeloid leukemia: a case report.
    Frontiers of medicine, 2018, Volume: 12, Issue:5

    Topics: Aged; Bridged Bicyclo Compounds, Heterocyclic; Combined Modality Therapy; Cytarabine; Fatal Outcome; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Recurrence; Remission Induction; Sulfonamides

2018
Congenital acute myeloid leukaemia with KMT2A rearrangement.
    British journal of haematology, 2018, Volume: 182, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Exanthema; Female; Gene Rearrangement; Histone-Lysine N-Methyltransferase; Humans; Infant, Newborn; Leukemia, Myeloid, Acute; Mitoxantrone; Myeloid-Lymphoid Leukemia Protein

2018
Validation of the prognostic value of the knowledge bank approach to determine AML prognosis in real life.
    Blood, 2018, 08-23, Volume: 132, Issue:8

    Topics: Adult; Aged; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Databases, Factual; Disease-Free Survival; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Predictive Value of Tests; Survival Rate

2018
A comparison of FLAG-Ida and daunorubicin combined with clofarabine in high-risk acute myeloid leukaemia: data from the UK NCRI AML17 Trial.
    Leukemia, 2018, Volume: 32, Issue:12

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Clofarabine; Cytarabine; Daunorubicin; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; United Kingdom; Vidarabine; Young Adult

2018
Outcome of relapsed or refractory acute myeloid leukemia treated with intensive salvage chemotherapy in real life in comparison to intermediate dose cytarabine in phase 3 studies.
    Leukemia & lymphoma, 2019, Volume: 60, Issue:1

    Topics: Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase III as Topic; Cytarabine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Recurrence, Local; Remission Induction; Salvage Therapy; Survival Analysis; Time Factors; Treatment Outcome

2019
Leukemic stem cell signatures identify novel therapeutics targeting acute myeloid leukemia.
    Blood cancer journal, 2018, 06-06, Volume: 8, Issue:6

    Topics: Apoptosis; Biomarkers; Biomarkers, Tumor; Cell Cycle; Cell Differentiation; Cell Line, Tumor; Computational Biology; Cytarabine; Drug Discovery; Drug Screening Assays, Antitumor; Gene Expression Profiling; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Molecular Targeted Therapy; Neoplastic Stem Cells; Transcriptome

2018
Preclinical characterization of INCB053914, a novel pan-PIM kinase inhibitor, alone and in combination with anticancer agents, in models of hematologic malignancies.
    PloS one, 2018, Volume: 13, Issue:6

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cytarabine; Dose-Response Relationship, Drug; Hematologic Neoplasms; Humans; Leukemia, Myeloid, Acute; Mice; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-pim-1; Signal Transduction

2018
Successful treatment of cytarabine-related neurotoxicity with corticosteroids, a case series.
    International journal of hematology, 2018, Volume: 108, Issue:5

    Topics: Adrenal Cortex Hormones; Adult; Aged; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Neurotoxicity Syndromes

2018
[Clinical Efficacy of Decitabine-Based Chemotherapy Regimens in the Treatment of Newly Diagnosed Elderly Patients with Acute Myeloid Leukemia].
    Zhongguo shi yan xue ye xue za zhi, 2018, Volume: 26, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Decitabine; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Middle Aged; Remission Induction; Treatment Outcome

2018
Lenalidomide combined with mismatched microtransplantation for acute myeloid leukemia.
    American journal of hematology, 2018, Volume: 93, Issue:10

    Topics: Aged; Allografts; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Consolidation Chemotherapy; Cytarabine; Drug Evaluation; Fatal Outcome; Female; Genes, sry; Histocompatibility; Humans; Immunologic Factors; Lenalidomide; Leukemia, Myeloid, Acute; Maintenance Chemotherapy; Male; Peripheral Blood Stem Cell Transplantation; Transplantation Chimera

2018
[Impact of KIT D816 mutation on salvage therapy in relapsed acute myeloid leukemia with t(8;21) translocation].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2018, Jun-14, Volume: 39, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Leukemia, Myeloid, Acute; Prognosis; Retrospective Studies; Salvage Therapy

2018
(1-3)-β-D-Glucan serum increase and small-airway-invasive radiological findings as early signs of pulmonary aspergillosis in high-risk hematologic patients in the posaconazole era: preliminary observations.
    Annals of hematology, 2019, Volume: 98, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; beta-Glucans; Cytarabine; Daunorubicin; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Pulmonary Aspergillosis; Retrospective Studies; Risk Factors; Triazoles; Vidarabine

2019
Benefit of nanomedicine confirmed in sAML.
    Nature reviews. Clinical oncology, 2018, Volume: 15, Issue:10

    Topics: Aged; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Liposomes; Nanomedicine

2018
Comprehensive Ara-C SNP score predicts leukemic cell intracellular ara-CTP levels in pediatric acute myeloid leukemia patients.
    Pharmacogenomics, 2018, 09-01, Volume: 19, Issue:14

    Topics: Adolescent; Adult; Child; Child, Preschool; Cytarabine; Cytidine Triphosphate; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Polymorphism, Single Nucleotide; Young Adult

2018
Emodin and Its Combination with Cytarabine Induce Apoptosis in Resistant Acute Myeloid Leukemia Cells in Vitro and in Vivo.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 48, Issue:5

    Topics: Animals; Apoptosis; Caspases; Cell Survival; Cytarabine; Drug Resistance, Neoplasm; Drug Therapy, Combination; Emodin; Extracellular Signal-Regulated MAP Kinases; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Mice; Mice, Inbred BALB C; Mice, Nude; Phosphatidylinositol 3-Kinases; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Signal Transduction; TOR Serine-Threonine Kinases

2018
[The Clinical Efficacy of Small Dose CAG Program in Comparison with MA Program in Senile Patients with Acute Myeloid Leukemia].
    Zhongguo shi yan xue ye xue za zhi, 2018, Volume: 26, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Prognosis; Retrospective Studies; Survival Rate; Treatment Outcome

2018
CPX-351 exhibits hENT-independent uptake and can be potentiated by fludarabine in leukaemic cells lines and primary refractory AML.
    Leukemia research, 2018, Volume: 74

    Topics: Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Equilibrative Nucleoside Transporter 1; HL-60 Cells; Humans; K562 Cells; Leukemia, Myeloid, Acute; Neoplasm Proteins; THP-1 Cells; Vidarabine

2018
n-3 Polyunsaturated fatty acids induce acute myeloid leukemia cell death associated with mitochondrial glycolytic switch and Nrf2 pathway activation.
    Pharmacological research, 2018, Volume: 136

    Topics: Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cytarabine; Energy Metabolism; Fatty Acids, Omega-3; Fish Oils; Glycolysis; Humans; Leukemia, Myeloid, Acute; Mitochondria; NF-E2-Related Factor 2; Signal Transduction

2018
Toward Predicting Acute Myeloid Leukemia Patient Response to 7 + 3 Induction Chemotherapy via Diagnostic Microdosing.
    Chemical research in toxicology, 2018, 10-15, Volume: 31, Issue:10

    Topics: Cell Line, Tumor; Cell Survival; Cytarabine; DNA; DNA Adducts; Drug Resistance, Neoplasm; Drug Therapy, Combination; Humans; Idarubicin; Leukemia, Myeloid, Acute; Mass Spectrometry

2018
Drug Shortage Impacts Patient Receipt of Induction Treatment.
    Health services research, 2018, Volume: 53, Issue:6

    Topics: Aged; Antimetabolites, Antineoplastic; Cytarabine; Female; Humans; Induction Chemotherapy; Insurance Claim Review; Leukemia, Myeloid, Acute; Male; Medicare; Retrospective Studies; SEER Program; United States

2018
Enhanced Anti-Leukemic Effects through Induction of Immunomodulating Microenvironment by Blocking CXCR4 and PD-L1 in an AML Mouse Model.
    Immunological investigations, 2019, Volume: 48, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; B7-H1 Antigen; Benzylamines; Cell Line, Tumor; Cyclams; Cytarabine; Disease Models, Animal; Heterocyclic Compounds; Humans; Immunomodulation; Immunotherapy; Leukemia, Myeloid, Acute; Mice; Mice, Inbred C57BL; Myeloid Progenitor Cells; Receptors, CXCR4; Tumor Microenvironment

2019
Upregulated microRNA-146a expression induced by granulocyte colony-stimulating factor enhanced low-dosage chemotherapy response in aged acute myeloid leukemia patients.
    Experimental hematology, 2018, Volume: 68

    Topics: Aclarubicin; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotaxis; Coculture Techniques; Cytarabine; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Leukemic; Granulocyte Colony-Stimulating Factor; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Male; MicroRNAs; Middle Aged; Neoplasm Proteins; NF-kappa B; Prognosis; Receptors, CXCR4; RNA Interference; RNA, Neoplasm; RNA, Small Interfering; Smad4 Protein; Stem Cell Niche; Tumor Microenvironment; Up-Regulation

2018
Effect of postremission high dose cytarabine-based consolidation chemotherapy before allogenic stem cell transplantation in outcomes of acute myeloid leukemia patients.
    Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis, 2018, Volume: 57, Issue:6

    Topics: Adult; Aged; Consolidation Chemotherapy; Cytarabine; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Stem Cell Transplantation; Transplantation, Homologous; Treatment Outcome; Young Adult

2018
Sequential reduced-intensity chemotherapy for allogeneic hematopoietic stem cell transplantation in acute myeloid leukemia with rare cytogenetic abnormalities transformed from Fanconi anemia.
    Pediatrics international : official journal of the Japan Pediatric Society, 2018, Volume: 60, Issue:9

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cytarabine; Fanconi Anemia; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Transplantation Conditioning; Transplantation, Homologous; Vidarabine

2018
Cytogenetics and gene mutations influence survival in older patients with acute myeloid leukemia treated with azacitidine or conventional care.
    Leukemia, 2018, Volume: 32, Issue:12

    Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Cytarabine; Cytogenetics; Female; Humans; Karyotype; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation

2018
FLAG salvage therapy combined with idarubicin in relapsed/refractory acute myeloid leukemia.
    Leukemia & lymphoma, 2019, Volume: 60, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Resistance, Neoplasm; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Remission Induction; Salvage Therapy; Treatment Outcome; Vidarabine; Young Adult

2019
Efficacy of common salvage chemotherapy regimens in patients with refractory or relapsed acute myeloid leukemia: A retrospective cohort study.
    Medicine, 2018, Volume: 97, Issue:39

    Topics: Aclarubicin; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cohort Studies; Cytarabine; Daunorubicin; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Harringtonines; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Retrospective Studies; Salvage Therapy; Survival Rate; Treatment Outcome; Vidarabine; Young Adult

2018
Self-nanoemulsifying system improves oral absorption and enhances anti-acute myeloid leukemia activity of berberine.
    Journal of nanobiotechnology, 2018, Oct-05, Volume: 16, Issue:1

    Topics: Absorption, Physiological; Administration, Oral; Animals; Antineoplastic Agents; Berberine; Cell Death; Cell Line, Tumor; Cell Survival; Cytarabine; Drug Interactions; Drug Liberation; Emulsions; Leukemia, Myeloid, Acute; Mice; Nanoparticles; Permeability; Phase Transition; Rabbits; Xenograft Model Antitumor Assays

2018
Histone deacetylase inhibitor targets CD123/CD47-positive cells and reverse chemoresistance phenotype in acute myeloid leukemia.
    Leukemia, 2019, Volume: 33, Issue:4

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; CD47 Antigen; Cell Cycle; Cytarabine; Depsipeptides; Drug Resistance, Neoplasm; Histone Deacetylase Inhibitors; Humans; Interleukin-3 Receptor alpha Subunit; Leukemia, Myeloid, Acute; Mice; Mice, Inbred NOD; Mice, SCID; Neoplastic Stem Cells; Phenotype; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2019
Cytomegalovirus meningitis in a patient with relapsed acute myeloid leukemia.
    International journal of hematology, 2019, Volume: 109, Issue:2

    Topics: Adult; Antiviral Agents; Cytarabine; Cytomegalovirus Infections; Diagnosis, Differential; Ganciclovir; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Meningitis, Viral; Recurrence; Treatment Outcome

2019
Lomustine in older patients with acute myeloid leukaemia.
    The Lancet. Oncology, 2018, Volume: 19, Issue:11

    Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Lomustine; Male; Middle Aged; Randomized Controlled Trials as Topic; Time Factors; Treatment Outcome

2018
Elevated Serum Exosomal miR-125b Level as a Potential Marker for Poor Prognosis in Intermediate-Risk Acute Myeloid Leukemia.
    Acta haematologica, 2018, Volume: 140, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cytarabine; Exosomes; Female; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; MicroRNAs; Middle Aged; Mitoxantrone; Prognosis; Proportional Hazards Models; Recurrence; Young Adult

2018
Second cycle remission achievement with 7+3 and survival in adults with newly diagnosed acute myeloid leukemia: analysis of recent SWOG trials.
    Leukemia, 2019, Volume: 33, Issue:2

    Topics: Adolescent; Adult; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Survival Rate; Treatment Outcome; Young Adult

2019
Relative survival following response to 7 + 3 versus azacytidine is similar in acute myeloid leukemia and high-risk myelodysplastic syndromes: an analysis of four SWOG studies.
    Leukemia, 2019, Volume: 33, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Clinical Trials as Topic; Cytarabine; Female; Follow-Up Studies; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Remission Induction; Risk Factors; Survival Rate; Treatment Outcome; Young Adult

2019
Allogeneic hematopoietic cell transplantation in chemotherapy-induced aplasia in children with high-risk acute myeloid leukemia or myelodysplasia.
    Pediatric blood & cancer, 2019, Volume: 66, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Female; Follow-Up Studies; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Myelodysplastic Syndromes; Neoplasm Recurrence, Local; Prognosis; Red-Cell Aplasia, Pure; Retrospective Studies; Transplantation Conditioning; Transplantation, Homologous; Vidarabine

2019
Low-level expression of SAMHD1 in acute myeloid leukemia (AML) blasts correlates with improved outcome upon consolidation chemotherapy with high-dose cytarabine-based regimens.
    Blood cancer journal, 2018, 10-19, Volume: 8, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Marrow; Combined Modality Therapy; Consolidation Chemotherapy; Cytarabine; Female; Gene Expression Regulation, Leukemic; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Proportional Hazards Models; SAM Domain and HD Domain-Containing Protein 1; Young Adult

2018
Long non-coding RNA taurine-upregulated gene 1 correlates with unfavorable prognosis in patients with refractory or relapsed acute myeloid leukemia treated by purine analogue based chemotherapy regimens.
    Cancer biomarkers : section A of Disease markers, 2018, Volume: 23, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Gene Expression Regulation, Neoplastic; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Purines; Remission Induction; RNA, Long Noncoding; Vidarabine

2018
Outcome and impact of post-remission strategy after MIDAM regimen in patients with relapsing or refractory acute myeloid leukemia.
    American journal of hematology, 2019, Volume: 94, Issue:1

    Topics: Adolescent; Adult; Aged; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Female; Gemtuzumab; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Recurrence; Salvage Therapy; Treatment Outcome; Young Adult

2019
Octadecyloxyethyl Adefovir Exhibits Potent in vitro and in vivo Cytotoxic Activity and Has Synergistic Effects with Ara-C in Acute Myeloid Leukemia.
    Chemotherapy, 2018, Volume: 63, Issue:4

    Topics: Adenine; Animals; Apoptosis; Caspases; Cell Cycle Checkpoints; Cytarabine; DNA Damage; Drug Compounding; Drug Resistance, Neoplasm; Drug Synergism; Female; Histones; Humans; Leukemia, Myeloid, Acute; Mice; Mice, Inbred NOD; Mice, SCID; Organophosphonates; Poly(ADP-ribose) Polymerases; Transplantation, Heterologous; Tumor Cells, Cultured

2018
Hydroxyurea prior to intensive chemotherapy in AML with moderate leukocytosis.
    Leukemia research, 2018, Volume: 75

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Hematopoietic Stem Cell Transplantation; Humans; Hydroxyurea; Induction Chemotherapy; Leukemia, Myeloid, Acute; Leukocytosis; Lomustine; Male; Middle Aged; Retrospective Studies; Treatment Outcome

2018
Inhibition of FAO in AML co-cultured with BM adipocytes: mechanisms of survival and chemosensitization to cytarabine.
    Scientific reports, 2018, 11-15, Volume: 8, Issue:1

    Topics: Activating Transcription Factor 4; Adenylate Kinase; Adipocytes; Adult; Bone Marrow; Cell Death; Cell Survival; Coculture Techniques; Cytarabine; Drug Synergism; Fatty Acids; Glycolysis; Humans; Leukemia, Myeloid, Acute; Middle Aged; Models, Biological; Oxidation-Reduction; Signal Transduction; THP-1 Cells; TOR Serine-Threonine Kinases; Young Adult

2018
Intensive chemotherapy vs. hypomethylating agents in older adults with newly diagnosed high-risk acute myeloid leukemia: A single center experience.
    Leukemia research, 2018, Volume: 75

    Topics: Aged; Aged, 80 and over; Anthracyclines; Antineoplastic Agents; Azacitidine; Cytarabine; Decitabine; Female; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Retrospective Studies

2018
The small-molecule compound AC-73 targeting CD147 inhibits leukemic cell proliferation, induces autophagy and increases the chemotherapeutic sensitivity of acute myeloid leukemia cells.
    Haematologica, 2019, Volume: 104, Issue:5

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Autophagy; Basigin; Cell Proliferation; Cytarabine; Drug Resistance, Neoplasm; Drug Synergism; Drug Therapy, Combination; Glycoproteins; Humans; Leukemia, Myeloid, Acute; Phenols; Prognosis; Signal Transduction; Small Molecule Libraries; Survival Rate; Tumor Cells, Cultured

2019
A precision medicine test predicts clinical response after idarubicin and cytarabine induction therapy in AML patients.
    Leukemia research, 2019, Volume: 76

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Drug Monitoring; Female; Humans; Idarubicin; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Precision Medicine; Prognosis; Remission Induction; ROC Curve; Treatment Outcome; Workflow; Young Adult

2019
Participation of vitamin D-upregulated protein 1 (TXNIP)-ASK1-JNK1 signalosome in the enhancement of AML cell death by a post-cytotoxic differentiation regimen.
    The Journal of steroid biochemistry and molecular biology, 2019, Volume: 187

    Topics: Abietanes; Antineoplastic Agents; Antioxidants; Carrier Proteins; Cell Line, Tumor; Cell Survival; Cytarabine; Ergocalciferols; Humans; Leukemia, Myeloid, Acute; MAP Kinase Kinase Kinase 5; Mitogen-Activated Protein Kinase 8; Signal Transduction; Vitamins

2019
Analysis of Efficacy and Prognostic Factors of CLAG Treatment in Chinese Patients with Refractory or Relapsed Acute Myeloid Leukemia.
    Acta haematologica, 2019, Volume: 141, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; China; Cladribine; Cytarabine; Drug Administration Schedule; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Logistic Models; Male; Middle Aged; Neutropenia; Prognosis; Proportional Hazards Models; Recurrence; Survival Rate; Treatment Outcome

2019
FLAG/FLAG-IDA regimen for children with relapsed/refractory acute leukemia in the era of targeted novel therapies.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2019, Volume: 25, Issue:8

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Infant; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Retrospective Studies; Vidarabine

2019
Validation of the 2017 European LeukemiaNet classification for acute myeloid leukemia with NPM1 and FLT3-internal tandem duplication genotypes.
    Cancer, 2019, 04-01, Volume: 125, Issue:7

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Consolidation Chemotherapy; Cytarabine; Europe; Female; fms-Like Tyrosine Kinase 3; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Induction Chemotherapy; L-Lactate Dehydrogenase; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Mutation; Nuclear Proteins; Nucleophosmin; Platelet Count; Prognosis; Reproducibility of Results; Retrospective Studies; Risk Assessment; Survival Rate; Young Adult

2019
Population Pharmacokinetics and Exposure-Response Analyses for CPX-351 in Patients With Hematologic Malignancies.
    Journal of clinical pharmacology, 2019, Volume: 59, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Female; Hematologic Neoplasms; Humans; Leukemia, Myeloid, Acute; Liposomes; Male; Middle Aged; Renal Insufficiency; Treatment Outcome

2019
Identification and targeting of novel CDK9 complexes in acute myeloid leukemia.
    Blood, 2019, 03-14, Volume: 133, Issue:11

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Biomarkers, Tumor; Carcinogenesis; Cell Proliferation; Cyclin-Dependent Kinase 9; Cytarabine; Humans; Leukemia, Myeloid, Acute; Mechanistic Target of Rapamycin Complex 1; Mechanistic Target of Rapamycin Complex 2; Mice; Mice, Nude; Phosphorylation; Protein Biosynthesis; Proteome; RNA, Messenger; Signal Transduction; TOR Serine-Threonine Kinases; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2019
Response-guided chemotherapy for pediatric acute myeloid leukemia without hematopoietic stem cell transplantation in first complete remission: Results from protocol DB AML-01.
    Pediatric blood & cancer, 2019, Volume: 66, Issue:5

    Topics: Adolescent; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Male; Nucleophosmin; Prognosis; Prospective Studies; Remission Induction; Survival Rate

2019
Acute Myeloid Leukemia Affects Mouse Sperm Parameters, Spontaneous Acrosome Reaction, and Fertility Capacity.
    International journal of molecular sciences, 2019, Jan-08, Volume: 20, Issue:1

    Topics: Acrosome Reaction; Animals; Cytarabine; Fertility; Leukemia, Myeloid, Acute; Male; Mice, Inbred C57BL; Sperm Motility; Spermatozoa; Survival Analysis

2019
Treatment with apremilast was beneficial for chronic graft-versus-host disease skin lesion in a patient with psoriasis.
    The Journal of dermatology, 2019, Volume: 46, Issue:6

    Topics: Administration, Oral; Biopsy; Bone Marrow Transplantation; Chronic Disease; Cytarabine; Graft vs Host Disease; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Phosphodiesterase 4 Inhibitors; Psoriasis; Skin; Thalidomide; Transplantation, Homologous; Treatment Outcome

2019
Comparison of neutropenia profiles in different treatment protocols for acute myeloid leukemia using the D-index.
    International journal of hematology, 2019, Volume: 109, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Neutropenia; Time Factors

2019
Results of program acute myeloid leukemia therapy use in National Medical Research Center for Hematology of the Ministry of Health of Russian Federation.
    Terapevticheskii arkhiv, 2018, Aug-17, Volume: 90, Issue:7

    Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Prognosis; Russia; Survival Rate; Young Adult

2018
In-silico comparison of two induction regimens (7 + 3 vs 7 + 3 plus additional bone marrow evaluation) in acute myeloid leukemia treatment.
    BMC systems biology, 2019, 01-31, Volume: 13, Issue:1

    Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cell Proliferation; Computer Simulation; Cytarabine; Disease Progression; Humans; Leukemia, Myeloid, Acute; Systems Biology; Time Factors

2019
Very rare lineage switch from acute myeloid leukemia to mixed phenotype acute leukemia, B/Myeloid, during chemotherapy with no clonal evolution.
    International journal of laboratory hematology, 2019, Volume: 41, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bone Marrow; Cytarabine; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged

2019
Health state utilities associated with treatment options for acute myeloid leukemia (AML).
    Journal of medical economics, 2019, Volume: 22, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Hospitalization; Humans; Induction Chemotherapy; Infusions, Intravenous; Interviews as Topic; Leukemia, Myeloid, Acute; Male; Middle Aged; Models, Economic; Patient Preference; Pilot Projects; Quality of Life; Socioeconomic Factors; Time Factors; United Kingdom

2019
Clinical Reasoning: A pregnant woman with chin numbness.
    Neurology, 2019, 02-26, Volume: 92, Issue:9

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bone Marrow; Chin; Consolidation Chemotherapy; Cytarabine; Emergency Service, Hospital; Fatigue; Female; Hematopoietic Stem Cell Transplantation; Humans; Hypesthesia; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Magnetic Resonance Imaging; Meningeal Carcinomatosis; Paresthesia; Pregnancy; Pregnancy Complications, Neoplastic; Spinal Puncture; Sweating; Upper Extremity

2019
Ambulatory Hematopoietic Stem Cell Transplantation in Young Adults with Acute Myeloid Leukemia Treated with Venetoclax and Low Doses of Cytarabine: Report of Two Cases.
    Journal of adolescent and young adult oncology, 2019, Volume: 8, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Combined Modality Therapy; Cytarabine; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Prognosis; Remission Induction; Salvage Therapy; Sulfonamides; Young Adult

2019
Potent and Highly Selective Aldo-Keto Reductase 1C3 (AKR1C3) Inhibitors Act as Chemotherapeutic Potentiators in Acute Myeloid Leukemia and T-Cell Acute Lymphoblastic Leukemia.
    Journal of medicinal chemistry, 2019, 04-11, Volume: 62, Issue:7

    Topics: Aldo-Keto Reductase Family 1 Member C3; Antineoplastic Agents; Cell Line, Tumor; Cytarabine; Daunorubicin; Drug Synergism; Enzyme Inhibitors; Humans; Leukemia, Myeloid, Acute; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Structure-Activity Relationship

2019
ARA-C RELATED RED EAR SYNDROME.
    Ear, nose, & throat journal, 2019, Volume: 98, Issue:3

    Topics: Adult; Antimetabolites, Antineoplastic; Cytarabine; Dermatitis, Exfoliative; Diagnosis, Differential; Ear Auricle; Ear Diseases; Female; Humans; Leukemia, Myeloid, Acute; Patient Care Management; Treatment Outcome

2019
Effect of CHK1 Inhibition on CPX-351 Cytotoxicity in vitro and ex vivo.
    Scientific reports, 2019, 03-05, Volume: 9, Issue:1

    Topics: Apoptosis; Cell Proliferation; Checkpoint Kinase 1; Cytarabine; Daunorubicin; G2 Phase Cell Cycle Checkpoints; Humans; In Vitro Techniques; Leukemia, Myeloid, Acute; Leukocytes, Mononuclear; Protein Kinase Inhibitors; Tumor Cells, Cultured

2019
Low ferroportin expression in AML is correlated with good risk cytogenetics, improved outcomes and increased sensitivity to chemotherapy.
    Leukemia research, 2019, Volume: 80

    Topics: Antimetabolites, Antineoplastic; Biomarkers, Tumor; Cation Transport Proteins; Cell Proliferation; Cytarabine; Cytogenetic Analysis; Humans; Leukemia, Myeloid, Acute; Prognosis; Survival Rate; Tumor Cells, Cultured

2019
Meningitis in a patient with neutropenia due to Rothia mucilaginosa: a case report.
    Journal of medical case reports, 2019, Mar-12, Volume: 13, Issue:1

    Topics: Actinomycetales Infections; Aged; Antimetabolites, Antineoplastic; Cytarabine; Fatal Outcome; Female; Humans; Leukemia, Myeloid, Acute; Meningitis; Neutropenia; Opportunistic Infections

2019
Cytarabine-Resistant
    International journal of molecular sciences, 2019, Mar-11, Volume: 20, Issue:5

    Topics: Anilides; Apoptosis Regulatory Proteins; Biomarkers; Cell Line, Tumor; Cell Survival; Cytarabine; DNA Mutational Analysis; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; fms-Like Tyrosine Kinase 3; Gene Deletion; Humans; Leukemia, Myeloid, Acute; Metabolic Networks and Pathways; Mutation; Pyridines; Tandem Repeat Sequences; Tumor Suppressor Protein p53

2019
Acute myeloid leukaemia: an unusual cause of biliary strictures.
    BMJ case reports, 2019, Mar-14, Volume: 12, Issue:3

    Topics: Adolescent; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Bile Ducts, Extrahepatic; Cholangiography; Cholangitis; Cholestasis; Constriction, Pathologic; Cytarabine; Daunorubicin; Drug Therapy; Humans; Jaundice, Obstructive; Leukemia, Myeloid, Acute; Male; Treatment Outcome

2019
Decitabine Versus Intensive Chemotherapy for Elderly Patients With Newly Diagnosed Acute Myeloid Leukemia.
    Clinical lymphoma, myeloma & leukemia, 2019, Volume: 19, Issue:5

    Topics: Age Factors; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Decitabine; Disease-Free Survival; DNA Methylation; Female; fms-Like Tyrosine Kinase 3; Follow-Up Studies; Gene Duplication; Humans; Idarubicin; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Prognosis; Remission Induction; Retrospective Studies; Time Factors

2019
Decitabine plus CLAG chemotherapy as a bridge to haploidentical transplantation in the setting of acute myeloid leukemia relapse after HLA-matched sibling transplantation: a case report.
    BMC cancer, 2019, Mar-18, Volume: 19, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cytarabine; Decitabine; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Histocompatibility Testing; HLA Antigens; Humans; Leukemia, Myeloid, Acute; Neoplasm Recurrence, Local; Remission Induction; Salvage Therapy; Siblings; Transplantation, Haploidentical; Treatment Outcome

2019
The EMA Review of Mylotarg (Gemtuzumab Ozogamicin) for the Treatment of Acute Myeloid Leukemia.
    The oncologist, 2019, Volume: 24, Issue:5

    Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Approval; Europe; Gemtuzumab; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Meta-Analysis as Topic; Randomized Controlled Trials as Topic; Risk Assessment; Sialic Acid Binding Ig-like Lectin 3

2019
Regulation of drug metabolizing enzymes in the leukaemic bone marrow microenvironment.
    Journal of cellular and molecular medicine, 2019, Volume: 23, Issue:6

    Topics: Bone Marrow; Bone Marrow Cells; Cell Line; Cell Line, Tumor; Cytarabine; Cytochrome P-450 CYP3A; Daunorubicin; Drug Resistance, Neoplasm; Etoposide; Humans; Inactivation, Metabolic; Leukemia, Myeloid, Acute; Stromal Cells; Tumor Microenvironment; Up-Regulation

2019
Quality of life and mood of older patients with acute myeloid leukemia (AML) receiving intensive and non-intensive chemotherapy.
    Leukemia, 2019, Volume: 33, Issue:10

    Topics: Affect; Aged; Aged, 80 and over; Anthracyclines; Antineoplastic Agents; Anxiety; Cytarabine; Depression; Female; Humans; Leukemia, Myeloid, Acute; Longitudinal Studies; Male; Middle Aged; Quality of Life

2019
Autologous hematopoetic cell transplantation: preferred consolidation treatment in low-risk AML?
    Leukemia & lymphoma, 2019, Volume: 60, Issue:10

    Topics: Cytarabine; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Transplantation, Autologous

2019
Acid ceramidase promotes drug resistance in acute myeloid leukemia through NF-κB-dependent P-glycoprotein upregulation.
    Journal of lipid research, 2019, Volume: 60, Issue:6

    Topics: Acid Ceramidase; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cell Survival; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Flow Cytometry; HEK293 Cells; HL-60 Cells; Humans; In Vitro Techniques; Lentivirus; Leukemia, Myeloid, Acute; Mitoxantrone; NF-kappa B; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Tandem Mass Spectrometry

2019
SETD2 mutations confer chemoresistance in acute myeloid leukemia partly through altered cell cycle checkpoints.
    Leukemia, 2019, Volume: 33, Issue:11

    Topics: Alleles; Animals; Cell Cycle; Cell Cycle Checkpoints; Cell Line, Tumor; Cytarabine; DNA Damage; Drug Resistance, Neoplasm; Epigenesis, Genetic; Female; Gene Expression Regulation, Leukemic; Heterozygote; Histone-Lysine N-Methyltransferase; Humans; Leukemia, Myeloid, Acute; Male; Mice; Mice, Transgenic; Mutation; Myeloid-Lymphoid Leukemia Protein; Neoplasm Recurrence, Local; Nuclear Proteins; Phenotype; Signal Transduction

2019
MALAT1 knockdown inhibits proliferation and enhances cytarabine chemosensitivity by upregulating miR-96 in acute myeloid leukemia cells.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 112

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cytarabine; Gene Knockdown Techniques; Humans; Leukemia, Myeloid, Acute; MicroRNAs; RNA, Long Noncoding; Up-Regulation

2019
FLT3-ITD cooperates with Rac1 to modulate the sensitivity of leukemic cells to chemotherapeutic agents via regulation of DNA repair pathways.
    Haematologica, 2019, Volume: 104, Issue:12

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biomarkers, Tumor; Cell Cycle; Cell Proliferation; Cytarabine; DNA Repair Enzymes; Drug Synergism; Female; fms-Like Tyrosine Kinase 3; Gene Expression Regulation, Neoplastic; GTPase-Activating Proteins; Guanine Nucleotide Exchange Factors; Humans; Leukemia, Myeloid, Acute; Mice; Mice, Inbred NOD; Mice, SCID; Pyrazoles; Pyrimidines; rac1 GTP-Binding Protein; Tandem Repeat Sequences; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2019
Anthracycline-based consolidation may determine outcome of post-consolidation immunotherapy in AML.
    Leukemia & lymphoma, 2019, Volume: 60, Issue:11

    Topics: Adolescent; Adult; Aged; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Humans; Immunotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Remission Induction; Survival Rate; T-Lymphocytes, Cytotoxic; Young Adult

2019
MicroRNAs Mediated Regulation of Expression of Nucleoside Analog Pathway Genes in Acute Myeloid Leukemia.
    Genes, 2019, 04-24, Volume: 10, Issue:4

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cytarabine; DCMP Deaminase; Deoxycytidine Kinase; Female; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Gene Regulatory Networks; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Male; Metabolic Networks and Pathways; MicroRNAs; Nucleosides; THP-1 Cells

2019
Coexistence of BCR/ABL1 p190 transcript and CEBPA double mutations in de novo acute myeloid leukemia.
    Leukemia & lymphoma, 2019, Volume: 60, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; CCAAT-Enhancer-Binding Proteins; Cytarabine; Fusion Proteins, bcr-abl; Humans; Idarubicin; Imatinib Mesylate; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Prognosis; Remission Induction

2019
Do we still need morphologic evaluation in new era of advanced minimal residual disease analyses?
    International journal of laboratory hematology, 2019, Volume: 41, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Cytarabine; Humans; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Neoplasm, Residual; Translocation, Genetic

2019
Evaluation of the impact of single-nucleotide polymorphisms on treatment response, survival and toxicity with cytarabine and anthracyclines in patients with acute myeloid leukaemia: a systematic review protocol.
    Systematic reviews, 2019, May-03, Volume: 8, Issue:1

    Topics: Anthracyclines; Antimetabolites, Antineoplastic; Cytarabine; Humans; Leukemia, Myeloid, Acute; Polymorphism, Single Nucleotide; Prognosis; Survival; Systematic Reviews as Topic

2019
Comparisons of commonly used front-line regimens on survival outcomes in patients aged 70 years and older with acute myeloid leukemia.
    Haematologica, 2020, Volume: 105, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Cytogenetic Analysis; Humans; Leukemia, Myeloid, Acute; Proportional Hazards Models; Retrospective Studies; Treatment Outcome

2020
Long-term follow-up of a trial comparing post-remission treatment with autologous or allogeneic bone marrow transplantation or intensive chemotherapy in younger acute myeloid leukemia patients.
    Haematologica, 2020, Volume: 105, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Remission Induction; Transplantation, Autologous

2020
A high-throughput screen indicates gemcitabine and JAK inhibitors may be useful for treating pediatric AML.
    Nature communications, 2019, 05-16, Volume: 10, Issue:1

    Topics: Adult; Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transplantation; Cell Line, Tumor; Child; Child, Preschool; Cytarabine; Deoxycytidine; Disease-Free Survival; Female; Gemcitabine; High-Throughput Screening Assays; Humans; Infant; Janus Kinase Inhibitors; Leukemia, Experimental; Leukemia, Myeloid, Acute; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Taxoids; Whole-Body Irradiation; Xenograft Model Antitumor Assays; Young Adult

2019
Surmounting Cytarabine-resistance in acute myeloblastic leukemia cells and specimens with a synergistic combination of hydroxyurea and azidothymidine.
    Cell death & disease, 2019, 05-17, Volume: 10, Issue:6

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cytarabine; Deoxycytidine Kinase; DNA Damage; Drug Resistance, Neoplasm; Drug Synergism; Histones; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Ubiquitination; Zidovudine

2019
Cytarabine ears - A side effect of cytarabine therapy.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2020, Volume: 26, Issue:2

    Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug-Related Side Effects and Adverse Reactions; Ear; Female; Hematologic Neoplasms; Humans; Leukemia, Myeloid, Acute; Middle Aged

2020
Expression of mitochondrial genes predicts survival in pediatric acute myeloid leukemia.
    International journal of hematology, 2019, Volume: 110, Issue:2

    Topics: Abnormal Karyotype; Adolescent; Allografts; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Daunorubicin; Etoposide; Female; Gene Expression Regulation, Leukemic; Genes, Mitochondrial; Hematopoietic Stem Cell Transplantation; Humans; Infant; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Mitochondrial Proteins; Neoplasm Proteins; Prognosis; Progression-Free Survival; Prospective Studies; Real-Time Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm

2019
The novel Isatin analog KS99 targets stemness markers in acute myeloid leukemia.
    Haematologica, 2020, Volume: 105, Issue:3

    Topics: Animals; Antigens, CD34; Cytarabine; Interleukin-3 Receptor alpha Subunit; Isatin; Leukemia, Myeloid, Acute; Mice; Neoplastic Stem Cells; Nucleophosmin

2020
FLAI induction regimen in elderly patients with acute myeloid leukemia.
    Leukemia & lymphoma, 2019, Volume: 60, Issue:13

    Topics: Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cytarabine; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoadjuvant Therapy; Remission Induction; Retrospective Studies; Sex Factors; Time Factors; Transplantation, Homologous; Vidarabine

2019
[Intermediate-high dose cytarabine consolidation therapy in younger adults with acute myeloid leukemia and favorable-intermediate cytogenetic risk: a retrospective study of 124 patients in a single Chinese hospital].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2019, 05-14, Volume: 40, Issue:5

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Consolidation Chemotherapy; Cytarabine; Cytogenetics; Humans; Leukemia, Myeloid, Acute; Remission Induction; Retrospective Studies; Treatment Outcome

2019
Impact of genotype in relapsed and refractory acute myeloid leukaemia patients treated with clofarabine and cytarabine: a retrospective study.
    British journal of haematology, 2019, Volume: 187, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clofarabine; Cytarabine; Drug Administration Schedule; Female; Follow-Up Studies; Genotype; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Prognosis; Recurrence; Retrospective Studies; Salvage Therapy; Survival Analysis; Young Adult

2019
A delayed diagnosis of acute myeloid leukaemia during pregnancy using an old blood cell analyser.
    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2019, Volume: 39, Issue:8

    Topics: Adult; Blood Cell Count; Cesarean Section; Cytarabine; Delayed Diagnosis; Female; Gestational Age; Humans; Isoflavones; Leukemia, Myeloid, Acute; Obstetric Labor, Premature; Pregnancy; Pregnancy Complications, Neoplastic; Pregnancy Outcome; Pregnancy, Twin; Remission Induction; Ritodrine

2019
SIRT3 deacetylase activity confers chemoresistance in AML via regulation of mitochondrial oxidative phosphorylation.
    British journal of haematology, 2019, Volume: 187, Issue:1

    Topics: Acetylation; Adult; Aged; Animals; Antimetabolites, Antineoplastic; Apoptosis; Cytarabine; Drug Resistance, Neoplasm; Female; Humans; Leukemia, Myeloid, Acute; Male; Mice, SCID; Middle Aged; Mitochondria; Oxidative Phosphorylation; Reactive Oxygen Species; Sirtuin 3; Superoxide Dismutase; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2019
Differentiation agents increase the potential AraC therapy of AML by reactivating cell death pathways without enhancing ROS generation.
    Journal of cellular physiology, 2020, Volume: 235, Issue:1

    Topics: Abietanes; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antioxidants; Apoptosis; Cell Line, Tumor; Cytarabine; Ergocalciferols; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Reactive Oxygen Species; Receptors, Calcitriol; RNA Interference; RNA, Small Interfering; U937 Cells; Vitamin D

2020
Optimizing venetoclax dose in combination with low intensive therapies in elderly patients with newly diagnosed acute myeloid leukemia: An exposure-response analysis.
    Hematological oncology, 2019, Volume: 37, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bridged Bicyclo Compounds, Heterocyclic; Clinical Trials, Phase I as Topic; Cytarabine; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid, Acute; Molecular Targeted Therapy; Remission Induction; Sulfonamides; Treatment Outcome

2019
Mathematical models for cytarabine-derived myelosuppression in acute myeloid leukaemia.
    PloS one, 2019, Volume: 14, Issue:7

    Topics: Cell Proliferation; Cytarabine; Humans; Leukemia, Myeloid, Acute; Models, Biological

2019
Clofarabine and cytarabine for acute myeloid leukaemia.
    The Lancet. Oncology, 2019, Volume: 20, Issue:8

    Topics: Arabinonucleosides; Clofarabine; Cytarabine; Humans; Leukemia, Myeloid, Acute

2019
Interleukin-8 blockade prevents activated endothelial cell mediated proliferation and chemoresistance of acute myeloid leukemia.
    Leukemia research, 2019, Volume: 84

    Topics: Antineoplastic Agents; Biomarkers; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytarabine; Drug Resistance, Neoplasm; Endothelial Cells; Humans; Interleukin-8; Leukemia, Myeloid, Acute; Models, Molecular; Structure-Activity Relationship

2019
Improving the Clinical Application of Natural Killer Cells by Modulating Signals Signal from Target Cells.
    International journal of molecular sciences, 2019, Jul-15, Volume: 20, Issue:14

    Topics: Cell Line, Tumor; Cells, Cultured; Clinical Trials as Topic; Cytarabine; Humans; Immunosuppressive Agents; Immunotherapy; Killer Cells, Natural; Leukemia, Myeloid, Acute; NK Cell Lectin-Like Receptor Subfamily K; Receptors, KIR; Signal Transduction

2019
Glasdegib with Low-Dose Cytarabine: A New Upfront Option for the Vulnerable AML Patient.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2019, 10-15, Volume: 25, Issue:20

    Topics: Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Cytarabine; Hedgehog Proteins; Humans; Leukemia, Myeloid, Acute; Phenylurea Compounds

2019
Epigenetic modifier gene mutations-positive AML patients with intermediate-risk karyotypes benefit from decitabine with CAG regimen.
    International journal of cancer, 2020, 03-01, Volume: 146, Issue:5

    Topics: Aclarubicin; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cytarabine; Decitabine; Disease-Free Survival; DNA Methylation; Drug Resistance, Neoplasm; Epigenesis, Genetic; Female; Genes, Modifier; Granulocyte Colony-Stimulating Factor; Humans; Kaplan-Meier Estimate; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Prognosis; Remission Induction; Retrospective Studies; Survival Rate; Young Adult

2020
Longitudinal minimal residual disease (MRD) evaluation in acute myeloid leukaemia with NPM1 mutation: from definition of molecular relapse to MRD-driven salvage approach.
    British journal of haematology, 2019, Volume: 186, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Etoposide; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Longitudinal Studies; Male; Middle Aged; Mitoxantrone; Mutation; Neoplasm Proteins; Neoplasm, Residual; Nuclear Proteins; Nucleophosmin; Recurrence; Salvage Therapy; Survival Rate

2019
Targeting Myeloperoxidase Disrupts Mitochondrial Redox Balance and Overcomes Cytarabine Resistance in Human Acute Myeloid Leukemia.
    Cancer research, 2019, Oct-15, Volume: 79, Issue:20

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Cell Line, Tumor; Cytarabine; Drug Resistance, Neoplasm; Gene Expression Profiling; Humans; Hypochlorous Acid; Leukemia, Myeloid, Acute; Membrane Potential, Mitochondrial; Mice; Mice, Inbred NOD; Mice, SCID; Mitochondria; Molecular Targeted Therapy; Neoplasm Proteins; Oxidation-Reduction; Oxidative Stress; Peroxidase; Reactive Oxygen Species; RNA, Neoplasm; RNA, Small Interfering; Transcriptome; Xenograft Model Antitumor Assays

2019
Delayed-onset effect of clofarabine in the treatment of an adult patient with acute myeloid leukemia.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2019, Feb-21, Volume: 76, Issue:6

    Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Blood Cell Count; Bone Marrow; Clofarabine; Cytarabine; Filgrastim; Humans; Leukemia, Myeloid, Acute; Male; Remission Induction; Time Factors; Treatment Outcome

2019
A novel alkylating deacetylase inhibitor molecule EDO-S101 in combination with cytarabine synergistically enhances apoptosis of acute myeloid leukemia cells.
    Medical oncology (Northwood, London, England), 2019, Aug-01, Volume: 36, Issue:9

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Apoptosis; Benzimidazoles; Cell Proliferation; Cell Survival; Cytarabine; DNA Damage; Drug Synergism; Histone Deacetylase Inhibitors; Humans; Leukemia, Myeloid, Acute; Tumor Cells, Cultured

2019
Prenylation-dependent Ras inhibition by pamidronate inhibits pediatric acute myeloid leukemia stem and differentiated cell growth and survival.
    Biochemical and biophysical research communications, 2019, 09-24, Volume: 517, Issue:3

    Topics: Anilides; Annexin A5; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzothiazoles; Bone Density Conservation Agents; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Child; Cytarabine; Daunorubicin; Drug Repositioning; Humans; Leukemia, Myeloid, Acute; Neoplastic Stem Cells; Pamidronate; Phenylurea Compounds; Primary Cell Culture; Protein Prenylation; Protein Processing, Post-Translational; Pyridines; ras Proteins

2019
Cytarabine, aclarubicin and granulocyte colony-stimulating factor regimen represents an effective and safe salvage regimen for patients with acute myeloid leukemia refractory to first course of induction chemotherapy.
    Leukemia & lymphoma, 2013, Volume: 54, Issue:11

    Topics: Aclarubicin; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Salvage Therapy; Treatment Outcome; Young Adult

2013
Induction mortality and resource utilization in children treated for acute myeloid leukemia at free-standing pediatric hospitals in the United States.
    Cancer, 2013, May-15, Volume: 119, Issue:10

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cohort Studies; Cytarabine; Daunorubicin; Dexamethasone; Etoposide; Female; Health Resources; Hospitals, Pediatric; Humans; Induction Chemotherapy; Infant; Leukemia, Myeloid, Acute; Logistic Models; Male; Odds Ratio; Poisson Distribution; Risk Assessment; Risk Factors; Thioguanine; Treatment Outcome; United States

2013
Core binding factor acute myeloid leukaemia and c-KIT mutations.
    Oncology reports, 2013, Volume: 29, Issue:5

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Chromosome Aberrations; Core Binding Factors; Cytarabine; Disease-Free Survival; Etoposide; Exons; Female; Humans; Idarubicin; L-Lactate Dehydrogenase; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Prognosis; Proto-Oncogene Proteins c-kit; Retrospective Studies; Stem Cell Transplantation; Young Adult

2013
Dermatic Scedosporium apiospermum infection after autologous bone marrow transplantation.
    Internal medicine (Tokyo, Japan), 2013, Volume: 52, Issue:6

    Topics: Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Dermatomycoses; Drugs, Chinese Herbal; Humans; Immunocompromised Host; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Opportunistic Infections; Postoperative Complications; Pyrimidines; Scedosporium; Skin Ulcer; Transplantation Conditioning; Transplantation, Autologous; Triazoles; Voriconazole; Young Adult

2013
[A man with neutropenic fever].
    Nederlands tijdschrift voor geneeskunde, 2013, Volume: 157, Issue:12

    Topics: Adult; Cytarabine; Dermatomycoses; Fatal Outcome; Fusarium; Humans; Immunocompromised Host; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Male; Neutropenia; Opportunistic Infections

2013
Does high-dose cytarabine cause cumulative toxicity in patients undergoing consolidation therapy for acute myeloid leukemia?
    American journal of hematology, 2013, Volume: 88, Issue:6

    Topics: Antimetabolites, Antineoplastic; Consolidation Chemotherapy; Cytarabine; Humans; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Remission Induction

2013
Florid skin rash in acute myeloid leukaemia.
    BMJ case reports, 2013, Mar-28, Volume: 2013

    Topics: Antimetabolites, Antineoplastic; Cytarabine; Drug Eruptions; Exanthema; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

2013
Resident rounds. Part III: Neutrophilic eccrine hidradenitis in the setting of acute myelogenous leukemia treated with cytarabine.
    Journal of drugs in dermatology : JDD, 2013, Volume: 12, Issue:2

    Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites, Antineoplastic; Cytarabine; Female; Hidradenitis; Humans; Leukemia, Myeloid, Acute; Middle Aged; Neutrophil Infiltration; Skin

2013
Aurora B inhibitor barasertib and cytarabine exert a greater-than-additive cytotoxicity in acute myeloid leukemia cells.
    Cancer science, 2013, Volume: 104, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Aurora Kinase B; Cell Division; Cell Line, Tumor; Cytarabine; Histones; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Organophosphates; Phosphorylation; Quinazolines; U937 Cells

2013
F14512, a polyamine-vectorized anti-cancer drug, currently in clinical trials exhibits a marked preclinical anti-leukemic activity.
    Leukemia, 2013, Volume: 27, Issue:11

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Boronic Acids; Bortezomib; Cell Proliferation; Cytarabine; Deoxycytidine; Doxorubicin; Fetal Blood; Flow Cytometry; Gemcitabine; Humans; Hydroxamic Acids; Immunoenzyme Techniques; Interleukin Receptor Common gamma Subunit; Leukemia, Myeloid, Acute; Mice; Mice, Inbred NOD; Mice, SCID; Podophyllotoxin; Pyrazines; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Survival Rate; Tumor Cells, Cultured; Vorinostat; Xenograft Model Antitumor Assays

2013
[Analysis on clinical response of IA and DA regimens in the treatment of 74 newly diagnosed acute myeloid leukemia patients].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2013, Volume: 34, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Treatment Outcome; Young Adult

2013
Accidental overdose of intrathecal cytarabine in children.
    The Annals of pharmacotherapy, 2013, Volume: 47, Issue:5

    Topics: Adolescent; Antimetabolites, Antineoplastic; Child, Preschool; Cytarabine; Drug Overdose; Female; Glucocorticoids; Humans; Injections, Spinal; Leukemia, Myeloid, Acute; Male; Medication Errors; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma

2013
Consolidation chemotherapy for adults with AML in first remission: is there a best choice?
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Jun-10, Volume: 31, Issue:17

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male

2013
[Refractory acute myeloid leukemia developed malignancy-associated hemophagocytic lymphohistiocytosis during treatment of invasive fungal infection].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2013, Volume: 54, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Fungal Infections; Child, Preschool; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Lymphohistiocytosis, Hemophagocytic; Mitoxantrone

2013
[Acute myeloid leukemia with monosomy 7 and inv(3)(q21q26.2) complicated with central diabetes insipidus].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2013, Volume: 54, Issue:4

    Topics: Chromosome Deletion; Chromosomes, Human, Pair 3; Chromosomes, Human, Pair 7; Cytarabine; Diabetes Insipidus, Neurogenic; Female; Humans; Karyotyping; Leukemia, Myeloid, Acute; Treatment Outcome; Young Adult

2013
CXCR4 downregulation of let-7a drives chemoresistance in acute myeloid leukemia.
    The Journal of clinical investigation, 2013, Volume: 123, Issue:6

    Topics: Adult; Aged; Animals; Antimetabolites, Antineoplastic; bcl-X Protein; Cell Line, Tumor; Chemokine CXCL12; Cytarabine; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Leukemic; Humans; Leukemia, Myeloid, Acute; Male; Mice; Mice, Inbred NOD; Mice, SCID; MicroRNAs; Middle Aged; Oligonucleotide Array Sequence Analysis; Receptors, CXCR4; Signal Transduction; Transcriptome; Tumor Burden; Xenograft Model Antitumor Assays; YY1 Transcription Factor

2013
Impact of polymorphisms in drug pathway genes on disease-free survival in adults with acute myeloid leukemia.
    Journal of human genetics, 2013, Volume: 58, Issue:6

    Topics: Adolescent; Adult; Aged; Busulfan; Chromosome Mapping; Cytarabine; Disease-Free Survival; DNA; Etoposide; Female; Follow-Up Studies; Genetic Loci; Genotype; Glutathione Transferase; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Membrane Transport Proteins; Middle Aged; Phenotype; Polymorphism, Single Nucleotide; Proportional Hazards Models; Remission Induction; Young Adult

2013
D-index dose not predict the development of pulmonary infection in acute myeloid leukemia patients undergoing consolidation chemotherapy with high-dose cytarabine.
    Hematology (Amsterdam, Netherlands), 2014, Volume: 19, Issue:2

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Consolidation Chemotherapy; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myeloid, Acute; Lung Diseases; Male; Middle Aged; Mitoxantrone; Neutropenia; Neutrophils; Predictive Value of Tests; Prognosis; Retrospective Studies; Risk Factors; Treatment Outcome; Young Adult

2014
De novo AML patients with favourable-intermediate karyotype may benefit from the addition of low-dose gemtuzumab ozogamicin (GO) to fludarabine, Ara-C and idarubicin (FLAI): a contribution to the reopened "GO question".
    Annals of hematology, 2013, Volume: 92, Issue:10

    Topics: Aged; Aged, 80 and over; Aminoglycosides; Antibodies, Monoclonal, Humanized; Cytarabine; Female; Gemtuzumab; Humans; Idarubicin; Karyotype; Leukemia, Myeloid, Acute; Male; Middle Aged; Prospective Studies; Treatment Outcome; Vidarabine

2013
Combination of fludarabine, amsacrine, and cytarabine followed by reduced-intensity conditioning and allogeneic hematopoietic stem cell transplantation in patients with high-risk acute myeloid leukemia.
    Annals of hematology, 2013, Volume: 92, Issue:10

    Topics: Adult; Amsacrine; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Vidarabine; Young Adult

2013
TGF-β-Neutralizing Antibody 1D11 Enhances Cytarabine-Induced Apoptosis in AML Cells in the Bone Marrow Microenvironment.
    PloS one, 2013, Volume: 8, Issue:6

    Topics: Animals; Antibodies, Neutralizing; Antineoplastic Agents; Apoptosis; Benzylamines; Bone Marrow; Cell Line, Tumor; Cell Movement; Cell Survival; Chemokine CXCL12; Coculture Techniques; Cyclams; Cytarabine; Female; Heterocyclic Compounds; Humans; Leukemia, Myeloid, Acute; Mice, SCID; Neoplasm Transplantation; Receptors, CXCR4; Transforming Growth Factor beta; Tumor Microenvironment

2013
[Effectiveness of anti-CD47 antibody and Ara-C combination targeting therapy NOD/SCID mouse of myeloid leukemia].
    Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2013, Volume: 15, Issue:7

    Topics: Animals; Antibodies, Monoclonal; CD47 Antigen; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Mice; Mice, Inbred NOD; Mice, SCID; Prognosis

2013
Decreased survival in normal karyotype AML with single-nucleotide polymorphisms in genes encoding the AraC metabolizing enzymes cytidine deaminase and 5'-nucleotidase.
    American journal of hematology, 2013, Volume: 88, Issue:12

    Topics: 5'-Nucleotidase; Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Cytidine Deaminase; Daunorubicin; Deoxycytidine Kinase; DNA Methylation; Drug Resistance, Neoplasm; Female; fms-Like Tyrosine Kinase 3; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Inactivation, Metabolic; Kaplan-Meier Estimate; Karyotype; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Proteins; Nucleophosmin; Polymorphism, Single Nucleotide; Prognosis; Proportional Hazards Models; Survival Analysis; Tandem Repeat Sequences; Topoisomerase I Inhibitors; Young Adult

2013
Elacytarabine (CP-4055) in the treatment of acute myeloid leukemia.
    Future oncology (London, England), 2013, Volume: 9, Issue:8

    Topics: Cytarabine; Drug Approval; Drug Resistance, Neoplasm; Drug-Related Side Effects and Adverse Reactions; Humans; Leukemia, Myeloid, Acute; Randomized Controlled Trials as Topic; Treatment Outcome

2013
[IAG regimen for patients with refractory/relapsed acute myeloid leukemia].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2013, Volume: 34, Issue:7

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Young Adult

2013
Blue toes and a new pair of shoes--challenges in diagnosis and treatment of acute myelogenous leukemia.
    American journal of hematology, 2013, Volume: 88, Issue:12

    Topics: Anticoagulants; Antineoplastic Combined Chemotherapy Protocols; Aorta, Abdominal; Arterial Occlusive Diseases; Bone Marrow Examination; Combined Modality Therapy; Cyanosis; Cytarabine; Diagnosis, Differential; Disseminated Intravascular Coagulation; Fatal Outcome; Female; Humans; Idarubicin; Ischemia; Leukemia, Myeloid, Acute; Magnetic Resonance Imaging; Middle Aged; Purpura, Thrombotic Thrombocytopenic; Shoes; Thrombectomy; Thrombocytopenia; Thrombosis; Toes; Ultrasonography

2013
Post-chemotherapeutic resolution of acute myeloid leukaemia-induced gingival enlargement: a case report.
    SADJ : journal of the South African Dental Association = tydskrif van die Suid-Afrikaanse Tandheelkundige Vereniging, 2012, Volume: 67, Issue:7

    Topics: Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Early Detection of Cancer; Female; Follow-Up Studies; Gingiva; Gingival Hemorrhage; Gingival Overgrowth; Gingivitis, Necrotizing Ulcerative; Humans; Leukemia, Myeloid, Acute; Leukemic Infiltration; Remission Induction

2012
The effect of decreased-dose idarubicin for elderly patients with acute myeloid leukemia.
    Japanese journal of clinical oncology, 2013, Volume: 43, Issue:10

    Topics: Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Idarubicin; Induction Chemotherapy; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Proportional Hazards Models; Retrospective Studies; Risk Assessment; Risk Factors; Treatment Outcome

2013
Outcomes of elderly de novo acute myeloid leukemia treated by a risk-adapted approach based on age, comorbidity, and performance status.
    American journal of hematology, 2013, Volume: 88, Issue:12

    Topics: Aged; Aged, 80 and over; Allografts; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Comorbidity; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Etoposide; Female; Gemtuzumab; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Remission Induction; Risk; Severity of Illness Index; Treatment Outcome

2013
Antibody-based delivery of interleukin-2 to neovasculature has potent activity against acute myeloid leukemia.
    Science translational medicine, 2013, Sep-04, Volume: 5, Issue:201

    Topics: Adult; Aged; Aged, 80 and over; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Biopsy; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Cytarabine; Disease Progression; Female; Fibronectins; HL-60 Cells; Humans; Interleukin-2; Leukemia, Myeloid, Acute; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Mice, SCID; Middle Aged; Neoplasm Transplantation; Neovascularization, Pathologic; Young Adult

2013
RRM1 and RRM2 pharmacogenetics: association with phenotypes in HapMap cell lines and acute myeloid leukemia patients.
    Pharmacogenomics, 2013, Volume: 14, Issue:12

    Topics: Cell Line, Tumor; Cladribine; Cytarabine; Genetic Association Studies; HapMap Project; Humans; Leukemia, Myeloid, Acute; Linkage Disequilibrium; Pharmacogenetics; Polymorphism, Single Nucleotide; Ribonucleoside Diphosphate Reductase; Tumor Suppressor Proteins

2013
Prevalence of extramedullary relapses is higher after allogeneic stem cell transplantation than after chemotherapy in adult patients with acute myeloid leukemia.
    Leukemia research, 2013, Volume: 37, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Recurrence, Local; Prevalence; Prognosis; Survival Rate; Transplantation Conditioning; Transplantation, Homologous; Young Adult

2013
Reduced-intensity conditioning therapy with fludarabine, idarubicin, busulfan and cytarabine for allogeneic hematopoietic stem cell transplantation in acute myeloid leukemia and myelodysplastic syndrome.
    Leukemia research, 2013, Volume: 37, Issue:11

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Female; Follow-Up Studies; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Neoplasm Recurrence, Local; Prevalence; Prognosis; Retrospective Studies; Survival Rate; Transplantation Conditioning; Transplantation, Homologous; Vidarabine; Young Adult

2013
Predictors and outcomes of viridans group streptococcal infections in pediatric acute myeloid leukemia: from the Canadian infections in AML research group.
    The Pediatric infectious disease journal, 2014, Volume: 33, Issue:2

    Topics: Anti-Bacterial Agents; Antimetabolites, Antineoplastic; Bacteremia; Canada; Child; Child, Preschool; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Retrospective Studies; Streptococcal Infections; Treatment Outcome; Viridans Streptococci

2014
Investigation and verification of a bioluminescent biosensor for the quantitation of ara-CTP generation: a biomarker for cytosine arabinoside sensitivity in acute myeloid leukaemia.
    Biosensors & bioelectronics, 2014, Feb-15, Volume: 52

    Topics: Arabinofuranosylcytosine Triphosphate; Biomarkers, Tumor; Biosensing Techniques; Cytarabine; Humans; Leukemia, Myeloid, Acute; Limit of Detection; Luminescent Measurements

2014
BH3 profiling discriminates response to cytarabine-based treatment of acute myelogenous leukemia.
    Molecular cancer therapeutics, 2013, Volume: 12, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Biomarkers; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Membrane Proteins; Middle Aged; Peptide Fragments; Proto-Oncogene Proteins; Remission Induction; ROC Curve; Treatment Outcome; Young Adult

2013
Predictive factors for latency period and a prognostic model for survival in patients with therapy-related acute myeloid leukemia.
    American journal of hematology, 2014, Volume: 89, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Models, Statistical; Neoplasms, Second Primary; Patient Outcome Assessment; Prognosis; Risk Factors; Treatment Outcome

2014
Medical image. A rare complication of cytarabine therapy.
    The New Zealand medical journal, 2013, Aug-16, Volume: 126, Issue:1380

    Topics: Antimetabolites, Antineoplastic; Cytarabine; Diagnosis, Differential; Female; Hand Dermatoses; Humans; Leukemia, Myeloid, Acute; Middle Aged

2013
Sorafenib as monotherapy or in association with cytarabine and clofarabine for the treatment of relapsed/refractory FLT3 ITD-positive advanced acute myeloid leukemia.
    Clinical lymphoma, myeloma & leukemia, 2014, Volume: 14, Issue:1

    Topics: Adenine Nucleotides; Adult; Arabinonucleosides; Clofarabine; Cytarabine; Female; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Neoplasm Recurrence, Local; Niacinamide; Phenylurea Compounds; Sorafenib; Tandem Repeat Sequences; Young Adult

2014
Breakthrough Fusarium solani infection in a patient with acute myeloid leukemia receiving posaconazole prophylaxis.
    Annals of hematology, 2014, Volume: 93, Issue:6

    Topics: Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Resistance, Fungal; Fatal Outcome; Female; Fever; Fusariosis; Fusarium; Humans; Idarubicin; Leukemia, Myeloid, Acute; Triazoles; Young Adult

2014
[Exudative pericardial effusion and oligoarthritis in a patient newly diagnosed with myelodysplastic syndrome].
    Medicina clinica, 2014, Jul-07, Volume: 143, Issue:1

    Topics: Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; Arthritis; Azacitidine; Cytarabine; Disease Progression; Etoposide; Fatal Outcome; Hepatomegaly; Humans; Idarubicin; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Male; Middle Aged; Pericardial Effusion; Pleural Effusion; Serositis

2014
Smac mimetic primes apoptosis-resistant acute myeloid leukaemia cells for cytarabine-induced cell death by triggering necroptosis.
    Cancer letters, 2014, Mar-01, Volume: 344, Issue:1

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Apoptosis Regulatory Proteins; Biomimetics; Blotting, Western; Cell Line, Tumor; Cytarabine; Drug Resistance, Neoplasm; Drug Synergism; Humans; Intracellular Signaling Peptides and Proteins; Leukemia, Myeloid, Acute; Mitochondrial Proteins; Oligopeptides

2014
Facts about FCE (fludarabine, cytarabine, etoposide) in acute myeloid leukemia.
    Acta haematologica, 2014, Volume: 131, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Salvage Therapy; Vidarabine

2014
The combination of fludarabine, cytarabine and etoposide is an active and well-tolerated regimen in relapsed/refractory acute myeloid leukemia.
    Acta haematologica, 2014, Volume: 131, Issue:4

    Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Combined Modality Therapy; Cytarabine; Drug Resistance, Neoplasm; Etoposide; Female; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Retrospective Studies; Salvage Therapy; Secondary Prevention; Survival Analysis; Vidarabine

2014
inv(2)(p23q13)/RAN-binding protein 2 (RANBP2)-ALK fusion gene in myeloid leukemia that developed in an elderly woman.
    International journal of hematology, 2014, Volume: 99, Issue:2

    Topics: Aged; Anaplastic Lymphoma Kinase; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Chromosome Inversion; Chromosomes, Human, Pair 2; Cytarabine; Daunorubicin; Diagnosis, Differential; Female; Humans; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Molecular Chaperones; Nuclear Pore Complex Proteins; Oncogene Proteins, Fusion; Receptor Protein-Tyrosine Kinases; Treatment Outcome

2014
Single-unit cord blood transplantation after granulocyte colony-stimulating factor-combined myeloablative conditioning for myeloid malignancies not in remission.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2014, Volume: 20, Issue:3

    Topics: Adolescent; Adult; Biomarkers; Cord Blood Stem Cell Transplantation; Cyclophosphamide; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cells; Humans; L-Lactate Dehydrogenase; Leukemia, Myeloid, Acute; Male; Middle Aged; Myeloablative Agonists; Myelodysplastic Syndromes; Prognosis; Survival Analysis; Transplantation Conditioning; Transplantation, Homologous

2014
Therapeutic antagonists of microRNAs deplete leukemia-initiating cell activity.
    The Journal of clinical investigation, 2014, Volume: 124, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Base Sequence; Binding Sites; Cell Transformation, Neoplastic; Combined Modality Therapy; Cytarabine; DNA-Binding Proteins; Doxorubicin; Gene Expression Regulation, Leukemic; Homeodomain Proteins; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, SCID; MicroRNAs; Myeloid Ecotropic Viral Integration Site 1 Protein; Neoplasm Proteins; Neoplastic Stem Cells; Phosphorothioate Oligonucleotides; Pre-B-Cell Leukemia Transcription Factor 1; Protein Binding; Proto-Oncogene Proteins; Regulatory Sequences, Nucleic Acid; Transcription Factors; Transcriptome; Xenograft Model Antitumor Assays

2014
Mutant DNMT3A clone evading chemotherapy and infiltrating central nervous system in a patient with molecularly good-risk acute myeloid leukemia.
    Annals of hematology, 2014, Volume: 93, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain; Clone Cells; Cytarabine; Daunorubicin; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; DNA, Neoplasm; Drug Resistance, Neoplasm; Female; Humans; Leukemia, Myeloid, Acute; Leukemic Infiltration; Middle Aged; Neoplasm Proteins; Neoplastic Stem Cells; Prognosis; Risk

2014
Apoptosis repressor with caspase recruitment domain is regulated by MAPK/PI3K and confers drug resistance and survival advantage to AML.
    Apoptosis : an international journal on programmed cell death, 2014, Volume: 19, Issue:4

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Caspases; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytarabine; Cytoskeletal Proteins; Drug Resistance, Neoplasm; Humans; Leukemia, Myeloid, Acute; Mesenchymal Stem Cells; Mice; Mice, Inbred NOD; Mice, SCID; Mitogen-Activated Protein Kinases; Neoplasm Transplantation; Nerve Tissue Proteins; Phosphatidylinositol 3-Kinases; Signal Transduction

2014
Impact of postremission consolidation chemotherapy on outcome after reduced-intensity conditioning allogeneic stem cell transplantation for patients with acute myeloid leukemia in first complete remission: a report from the Acute Leukemia Working Party of
    Cancer, 2014, Mar-15, Volume: 120, Issue:6

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Consolidation Chemotherapy; Cytarabine; Disease-Free Survival; Female; Graft vs Host Disease; Humans; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Recurrence, Local; Retrospective Studies; Stem Cell Transplantation; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Young Adult

2014
[Cytarabine and skin reactions in acute myeloid leukemia].
    Medicina, 2013, Volume: 73, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Cytarabine; Drug Eruptions; Female; Humans; Incidence; Leukemia, Myeloid, Acute; Male; Middle Aged; Retrospective Studies; Risk Factors; Severity of Illness Index; Statistics, Nonparametric; Young Adult

2013
Knockdown of CD44 enhances chemosensitivity of acute myeloid leukemia cells to ADM and Ara-C.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2014, Volume: 35, Issue:4

    Topics: Antineoplastic Agents; Cell Proliferation; Cytarabine; Doxorubicin; Drug Resistance, Neoplasm; HL-60 Cells; Humans; Hyaluronan Receptors; Leukemia, Myeloid, Acute; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc

2014
Fractionated gemtuzumab ozogamicin and standard dose cytarabine produced prolonged second remissions in patients over the age of 55 years with acute myeloid leukemia in late first relapse.
    American journal of hematology, 2014, Volume: 89, Issue:4

    Topics: Aged; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Compassionate Use Trials; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Filgrastim; Gemtuzumab; Granulocyte Colony-Stimulating Factor; Humans; Immunophenotyping; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Male; Methylprednisolone; Middle Aged; Neutropenia; Nucleophosmin; Recombinant Proteins; Remission Induction; Salvage Therapy; Thrombocytopenia

2014
Allogeneic stem cell transplantation as initial salvage for patients with acute myeloid leukemia refractory to high-dose cytarabine-based induction chemotherapy.
    American journal of hematology, 2014, Volume: 89, Issue:4

    Topics: Adult; Aged; Allografts; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Disease-Free Survival; Drug Resistance, Neoplasm; Hematopoietic Stem Cell Transplantation; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Middle Aged; Neoplastic Stem Cells; Prognosis; Proportional Hazards Models; Remission Induction; Retrospective Studies; Risk Factors; Salvage Therapy; Transplantation Conditioning; Treatment Outcome; Young Adult

2014
Fludarabine, cytarabine, granulocyte colony-stimulating factor and melphalan (FALG with L-PAM) as a reduced toxicity conditioning regimen in children with acute leukemia.
    Pediatric blood & cancer, 2014, Volume: 61, Issue:4

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Female; Follow-Up Studies; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Humans; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Male; Melphalan; Neoplasm Recurrence, Local; Postoperative Complications; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Remission Induction; Survival Rate; Transplantation Conditioning; Transplantation, Homologous; Vidarabine; Whole-Body Irradiation

2014
Epigenetics meets genetics in acute myeloid leukemia: clinical impact of a novel seven-gene score.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014, Feb-20, Volume: 32, Issue:6

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; DNA Methylation; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Myeloid, Acute; Middle Aged; Mutation; Predictive Value of Tests; Prognosis; Severity of Illness Index

2014
Prediction of adverse events during intensive induction chemotherapy for acute myeloid leukemia or high-grade myelodysplastic syndromes.
    American journal of hematology, 2014, Volume: 89, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bacteremia; Blood Cell Count; Critical Care; Cyclophosphamide; Cytarabine; Daunorubicin; Febrile Neutropenia; Female; Granulocyte Colony-Stimulating Factor; Humans; Immunocompromised Host; Infections; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Myelodysplastic Syndromes; Proportional Hazards Models; Remission Induction; Retrospective Studies; Young Adult

2014
Crucial role of heme oxygenase-1 in the sensitivity of acute myeloid leukemia cell line Kasumi-1 to ursolic acid.
    Anti-cancer drugs, 2014, Volume: 25, Issue:4

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cytarabine; Drug Resistance, Neoplasm; Drug Synergism; Heme Oxygenase-1; Humans; Leukemia, Myeloid, Acute; Mice; Neoplasm Transplantation; Protoporphyrins; Triterpenes; Ursolic Acid

2014
Laryngeal chloroma heralding relapse of acute myeloid leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014, Mar-01, Volume: 32, Issue:7

    Topics: Acute Disease; Antimetabolites, Antineoplastic; Cytarabine; Disease Progression; Dose Fractionation, Radiation; Fatal Outcome; Humans; Laryngeal Neoplasms; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Recurrence, Local; Palliative Care; Respiratory Insufficiency; Sarcoma, Myeloid; Stem Cell Transplantation; Tomography, X-Ray Computed

2014
The percentage of peripheral blood blasts on day 7 of induction chemotherapy predicts response to therapy and survival in patients with acute myeloid leukemia.
    Chinese medical journal, 2014, Volume: 127, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Child; Cytarabine; Female; Flow Cytometry; Humans; Idarubicin; Immunophenotyping; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Recurrence, Local; Young Adult

2014
Cladribine, cytarabine, filgrastim, and mitoxantrone (CLAG-M) compared to standard induction in acute myeloid leukemia from myelodysplastic syndrome after azanucleoside failure.
    Leukemia research, 2014, Volume: 38, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Case-Control Studies; Chemotherapy, Adjuvant; Cladribine; Cytarabine; Disease Progression; Drug Resistance, Neoplasm; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Myelodysplastic Syndromes; Recombinant Proteins; Treatment Failure; Young Adult

2014
Normal karyotype acute myeloid leukemia with the CD7+ CD15+ CD34+ HLA-DR + immunophenotype is a clinically distinct entity with a favorable outcome.
    Annals of hematology, 2014, Volume: 93, Issue:6

    Topics: Adolescent; Adult; Aged; Antigens, CD34; Antigens, CD7; Antimetabolites, Antineoplastic; CCAAT-Enhancer-Binding Proteins; Cytarabine; Female; Fucosyltransferases; HLA-DR Antigens; Humans; Immunophenotyping; Kaplan-Meier Estimate; Karyotype; Karyotyping; Leukemia, Myeloid, Acute; Leukocyte Count; Lewis X Antigen; Male; Middle Aged; Multicenter Studies as Topic; Proportional Hazards Models; Randomized Controlled Trials as Topic; Retrospective Studies; Risk Assessment; Treatment Outcome; Young Adult

2014
Effective salvage therapy for high-risk relapsed or refractory acute myeloid leukaemia with cisplatin in combination with high-dose cytarabine and etoposide.
    European journal of haematology, 2014, Volume: 92, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cytarabine; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Recurrence; Salvage Therapy; Treatment Outcome; Young Adult

2014
Cladribine in the treatment of acute myeloid leukemia.
    Leukemia research, 2014, Volume: 38, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cladribine; Cytarabine; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Myelodysplastic Syndromes; Recombinant Proteins

2014
Acute myeloid leukemia of mixed megakaryocytic and erythroid origin following chemotherapy for T-cell lymphoblastic lymphoma.
    International journal of hematology, 2014, Volume: 99, Issue:3

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cytarabine; Daunorubicin; Dexamethasone; Erythroid Cells; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Mediastinal Neoplasms; Megakaryocytes; Mitoxantrone; Neoplasms, Second Primary; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Vincristine

2014
Sequential treatment with cytarabine and decitabine has an increased anti-leukemia effect compared to cytarabine alone in xenograft models of childhood acute myeloid leukemia.
    PloS one, 2014, Volume: 9, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Decitabine; Gene Expression Profiling; Humans; Leukemia, Myeloid, Acute; Mice; Mice, Inbred NOD; Mice, SCID; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2014
Prognostic factor analysis in core-binding factor-positive acute myeloid leukemia.
    Anticancer research, 2014, Volume: 34, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Core Binding Factors; Cytarabine; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Prognosis; Translocation, Genetic; Treatment Outcome; Young Adult

2014
Characteristics and clinical evolution of patients with acute myeloblastic leukemia in northeast Mexico: an eight-year experience at a university hospital.
    Acta haematologica, 2014, Volume: 132, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Antineoplastic Combined Chemotherapy Protocols; Blood Component Transfusion; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Dexamethasone; Disease-Free Survival; Doxorubicin; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Hospitals, University; Humans; Infant; Infusions, Intravenous; Injections, Spinal; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Male; Methotrexate; Mexico; Middle Aged; Mitoxantrone; Proportional Hazards Models; Retrospective Studies; Risk Factors; Treatment Outcome; Young Adult

2014
Prognostic value of IDH1 mutations identified with PCR-RFLP assay in acute myeloid leukemia patients.
    Journal of the Egyptian National Cancer Institute, 2014, Volume: 26, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; DNA Mutational Analysis; Doxorubicin; Female; Genetic Association Studies; Humans; Isocitrate Dehydrogenase; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Prognosis; Treatment Outcome; Tretinoin; Young Adult

2014
Increasing the dose of aclarubicin in low-dose cytarabine and aclarubicin in combination with granulocyte colony-stimulating factor (CAG regimen) can safely and effectively treat relapsed or refractory acute myeloid leukemia.
    International journal of hematology, 2014, Volume: 99, Issue:5

    Topics: Aclarubicin; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Remission Induction; Treatment Outcome; Young Adult

2014
Azacitidine and low-dose cytarabine in palliative patients with acute myeloid leukemia and high bone marrow blast counts--a retrospective single-center experience.
    European journal of haematology, 2014, Volume: 93, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bone Marrow; Cytarabine; Drug Administration Schedule; Female; Hemorrhage; Humans; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Neutropenia; Palliative Care; Pneumonia; Retrospective Studies; Survival Analysis

2014
HLA-partially matched cellular therapy (stem-cell microtransplantation) for acute myeloid leukaemia: description of four cases.
    British journal of haematology, 2014, Volume: 165, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Graft Survival; Graft vs Leukemia Effect; Histocompatibility; HLA Antigens; Humans; Idarubicin; Leukemia, Myeloid, Acute; Leukocyte Transfusion; Male; Middle Aged; Remission Induction; Tissue Donors

2014
[Observation of low-dose HA/HAA regimen as induction chemotherapy on elderly patients with acute myeloid leukemia].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2014, Volume: 35, Issue:3

    Topics: Aged; Aged, 80 and over; Cytarabine; Female; Harringtonines; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged

2014
c-Myc regulates expression of NKG2D ligands ULBP1/2/3 in AML and modulates their susceptibility to NK-mediated lysis.
    Blood, 2014, Jun-05, Volume: 123, Issue:23

    Topics: Antimetabolites, Antineoplastic; Cell Death; Cells, Cultured; Cytarabine; Cytotoxicity, Immunologic; Drug Resistance, Neoplasm; Gene Expression Regulation, Leukemic; GPI-Linked Proteins; HL-60 Cells; Humans; Intercellular Signaling Peptides and Proteins; Intracellular Signaling Peptides and Proteins; Killer Cells, Natural; Leukemia, Myeloid, Acute; Ligands; NK Cell Lectin-Like Receptor Subfamily K; Proto-Oncogene Proteins c-myc

2014
Cytarabine-resistant leukemia cells are moderately sensitive to clofarabine in vitro.
    Anticancer research, 2014, Volume: 34, Issue:4

    Topics: Adenine Nucleotides; Antimetabolites, Antineoplastic; Apoptosis; Arabinonucleosides; Cell Line, Tumor; Cell Proliferation; Clofarabine; Cytarabine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Equilibrative Nucleoside Transporter 1; HL-60 Cells; Humans; Intracellular Space; Leukemia, Myeloid, Acute; Membrane Transport Proteins; Phosphotransferases (Alcohol Group Acceptor)

2014
MicroRNA-155 as an inducer of apoptosis and cell differentiation in Acute Myeloid Leukaemia.
    Molecular cancer, 2014, Apr-05, Volume: 13

    Topics: Antigens, CD; Antimetabolites, Antineoplastic; Apoptosis; Caspase 3; Cell Differentiation; Cell Proliferation; Cytarabine; Epigenesis, Genetic; fms-Like Tyrosine Kinase 3; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; MicroRNAs; Mutation; Neoplasm Proteins; Signal Transduction; Survival Analysis; Tumor Cells, Cultured

2014
Low-dose homoharringtonine and cytarabine in combination with granulocyte colony-stimulating factor for elderly patients with de novo acute myeloid leukemia.
    Leukemia & lymphoma, 2015, Volume: 56, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Harringtonines; Homoharringtonine; Humans; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Nucleophosmin; Survival Analysis; Treatment Outcome

2015
Efficacy and feasibility of cyclophosphamide combined with intermediate- dose or high-dose cytarabine for relapsed and refractory acute myeloid leukemia (AML).
    Journal of cancer research and clinical oncology, 2014, Volume: 140, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; DNA Mutational Analysis; Drug Resistance, Neoplasm; Feasibility Studies; Female; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Recurrence, Local; Proto-Oncogene Proteins c-kit; Retrospective Studies; Salvage Therapy; Survival Analysis; Treatment Outcome; Young Adult

2014
Standard intensive chemotherapy is less effective and far more toxic than attenuated induction and post-induction regimen in elderly patients with acute myeloid leukemia.
    Medical oncology (Northwood, London, England), 2014, Volume: 31, Issue:5

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Neoplasm Staging; Prognosis; Prospective Studies; Remission Induction; Survival Rate

2014
An intragenic long noncoding RNA interacts epigenetically with the RUNX1 promoter and enhancer chromatin DNA in hematopoietic malignancies.
    International journal of cancer, 2014, Dec-15, Volume: 135, Issue:12

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Chromatin; Chromosome Aberrations; Chromosomes; Core Binding Factor Alpha 2 Subunit; Cytarabine; DNA; Enhancer Elements, Genetic; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Exome; Gene Expression Regulation, Leukemic; HeLa Cells; Hematologic Neoplasms; Humans; K562 Cells; Leukemia, Myeloid, Acute; Mutation; Polycomb Repressive Complex 2; Promoter Regions, Genetic; RNA, Long Noncoding; Translocation, Genetic

2014
[Treatment of acute myeloid leukemia -- a single center experience (2007-2013)].
    Orvosi hetilap, 2014, Apr-27, Volume: 155, Issue:17

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Bortezomib; Cytarabine; Daunorubicin; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Hungary; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Neoplasm, Residual; Palliative Care; Prognosis; Pyrazines; Retrospective Studies; Survival Analysis; Survival Rate; Transplantation, Homologous; Treatment Outcome; Vidarabine

2014
miR-181b increases drug sensitivity in acute myeloid leukemia via targeting HMGB1 and Mcl-1.
    International journal of oncology, 2014, Volume: 45, Issue:1

    Topics: 3' Untranslated Regions; Adolescent; Adult; Aged; Antineoplastic Agents; Cell Line, Tumor; Cytarabine; Doxorubicin; Drug Resistance, Neoplasm; Female; HL-60 Cells; HMGB1 Protein; Humans; K562 Cells; Leukemia, Myeloid, Acute; Male; MicroRNAs; Middle Aged; Myeloid Cell Leukemia Sequence 1 Protein; Young Adult

2014
Sensitivity of MLL-rearranged AML cells to all-trans retinoic acid is associated with the level of H3K4me2 in the RARα promoter region.
    Blood cancer journal, 2014, Apr-25, Volume: 4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Cycle Checkpoints; Cell Differentiation; Cytarabine; DNA-Binding Proteins; Drug Synergism; Histone-Lysine N-Methyltransferase; Histones; Humans; Leukemia, Myeloid, Acute; Myeloid-Lymphoid Leukemia Protein; Neoplasm Proteins; Nuclear Proteins; Promoter Regions, Genetic; Proto-Oncogene Proteins; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Trans-Activators; Transcriptional Activation; Transcriptional Elongation Factors; Tretinoin

2014
[Contribution of PET/CT for the management of hepatosplenic candidiasis in hematology].
    Medecine et maladies infectieuses, 2014, Volume: 44, Issue:6

    Topics: Amphotericin B; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Candidiasis, Invasive; Chemotherapy-Induced Febrile Neutropenia; Cytarabine; Daunorubicin; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Hepatitis; Humans; Immunocompromised Host; Leukemia, Myeloid, Acute; Male; Middle Aged; Multimodal Imaging; Positron-Emission Tomography; Radiopharmaceuticals; Splenic Diseases; Tomography, X-Ray Computed

2014
The first Korean case of Moraxella osloensis bacteremia in a patient with acute myeloid leukemia.
    Annals of laboratory medicine, 2014, Volume: 34, Issue:3

    Topics: Aged; Ampicillin; Anti-Bacterial Agents; Antimetabolites, Antineoplastic; Asian People; Cytarabine; Drug Therapy, Combination; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Moraxella; Moraxellaceae Infections; Republic of Korea; Respiratory Tract Infections; RNA, Ribosomal, 16S; Sequence Analysis, RNA; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulbactam

2014
High prognostic value of minimal residual disease detected by flow-cytometry-enhanced fluorescence in situ hybridization in core-binding factor acute myeloid leukemia (CBF-AML).
    Annals of hematology, 2014, Volume: 93, Issue:10

    Topics: Adolescent; ADP-ribosyl Cyclase 1; Adult; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Cell Separation; Chromosome Aberrations; Consolidation Chemotherapy; Core Binding Factor Alpha 2 Subunit; Cytarabine; Daunorubicin; Female; Flow Cytometry; Humans; In Situ Hybridization, Fluorescence; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm, Residual; Neoplastic Stem Cells; Oncogene Proteins, Fusion; Prognosis; RUNX1 Translocation Partner 1 Protein; Young Adult

2014
Factors affecting outcome of allogeneic stem cell transplantation as salvage in patients with acute myeloid leukemia primary refractory to intensive induction therapy.
    American journal of hematology, 2014, Volume: 89, Issue:9

    Topics: Cytarabine; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Salvage Therapy

2014
Health economic impact of high-dose versus standard-dose cytarabine induction chemotherapy for acute myeloid leukaemia.
    Internal medicine journal, 2014, Volume: 44, Issue:8

    Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Cytarabine; Dose-Response Relationship, Drug; Drug Costs; Female; Follow-Up Studies; Health Care Costs; Health Resources; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Retrospective Studies; Victoria; Young Adult

2014
The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation.
    Nature, 2014, Jul-03, Volume: 511, Issue:7507

    Topics: Cell Line, Tumor; Cytarabine; Drug Resistance, Neoplasm; Gene Deletion; Glucuronic Acid; Glucuronosyltransferase; Hedgehog Proteins; Humans; Leukemia, Myeloid, Acute; Ribavirin; Signal Transduction; Transcription Factors; Zinc Finger Protein GLI1

2014
Toxicity and efficacy of intrathecal liposomal cytarabine in children with leukemia/lymphoma relapsing in the central nervous system: a retrospective multicenter study.
    Leukemia & lymphoma, 2015, Volume: 56, Issue:3

    Topics: Adolescent; Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Child; Child, Preschool; Cytarabine; Female; Humans; Infant; Injections, Spinal; Leukemia, Myeloid, Acute; Liposomes; Lymphoma, Non-Hodgkin; Male; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies

2015
Critical considerations on the utility of FDG-PET/CT for posttreatment restaging of the bone marrow in diffuse large B-cell lymphoma.
    American journal of hematology, 2014, Volume: 89, Issue:9

    Topics: Cytarabine; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Salvage Therapy

2014
Critical considerations on the utility of 18F-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography for posttreatment restaging of the bone marrow in diffuse large B-cell lymphoma.
    American journal of hematology, 2014, Volume: 89, Issue:9

    Topics: Cytarabine; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Salvage Therapy

2014
Enhanced skin toxicity associated with the combination of clofarabine plus cytarabine for the treatment of acute leukemia.
    Cancer chemotherapy and pharmacology, 2014, Volume: 74, Issue:2

    Topics: Adenine Nucleotides; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cytarabine; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Retrospective Studies; Skin Diseases

2014
The ROS/SUMO axis contributes to the response of acute myeloid leukemia cells to chemotherapeutic drugs.
    Cell reports, 2014, Jun-26, Volume: 7, Issue:6

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cytarabine; Daunorubicin; Disease Models, Animal; Etoposide; Female; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Male; Mice; Mice, Nude; Microarray Analysis; Reactive Oxygen Species; SUMO-1 Protein; U937 Cells; Xenograft Model Antitumor Assays

2014
Acute basophilic leukemia.
    Blood, 2014, May-15, Volume: 123, Issue:20

    Topics: Aged; Antibiotics, Antineoplastic; Antigens, CD; Antimetabolites, Antineoplastic; Asthenia; Azacitidine; Basophils; Bone Marrow; Cytarabine; Female; Humans; Idarubicin; Leukemia, Basophilic, Acute; Leukemia, Myeloid, Acute

2014
Outcome of children with relapsed acute myeloid leukemia following initial therapy under the AML99 protocol.
    International journal of hematology, 2014, Volume: 100, Issue:2

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Child; Child, Preschool; Cytarabine; Etoposide; Female; fms-Like Tyrosine Kinase 3; Gene Duplication; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Infant; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Prognosis; Recurrence; Remission Induction; Retrospective Studies; Survival Analysis; Transplantation, Homologous; Treatment Outcome

2014
Transplant-acquired food allergy (TAFA) following cord blood stem cell transplantation in two adult patients with haematological malignancies.
    British journal of haematology, 2014, Volume: 167, Issue:3

    Topics: Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cord Blood Stem Cell Transplantation; Cytarabine; Daunorubicin; Drug Therapy, Combination; Egg Hypersensitivity; Etoposide; Female; Food Hypersensitivity; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Immunosuppressive Agents; Intestinal Diseases; Leukemia, Myeloid, Acute; Liver Diseases; Male; Middle Aged; Nut Hypersensitivity; Seafood; Tacrolimus; Transplantation Conditioning; Vidarabine

2014
Targeting the wee1 kinase for treatment of pediatric Down syndrome acute myeloid leukemia.
    Pediatric blood & cancer, 2014, Volume: 61, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Child; Cytarabine; Down Syndrome; Drug Synergism; Flow Cytometry; Humans; Leukemia, Myeloid, Acute; Nuclear Proteins; Protein-Tyrosine Kinases; Pyrazoles; Pyrimidines; Pyrimidinones; Reverse Transcriptase Polymerase Chain Reaction

2014
Liposomal daunorubicin, fludarabine, and cytarabine (FLAD) as bridge therapy to stem cell transplant in relapsed and refractory acute leukemia.
    Annals of hematology, 2014, Volume: 93, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Component Transfusion; Combined Modality Therapy; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Diarrhea; Drug Administration Schedule; Drug Evaluation; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Liposomes; Male; Middle Aged; Neutropenia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proportional Hazards Models; Remission Induction; Retrospective Studies; Salvage Therapy; Vidarabine; Young Adult

2014
Gemtuzumab ozogamicin with fludarabine, cytarabine, and granulocyte colony stimulating factor (FLAG-GO) as front-line regimen in patients with core binding factor acute myelogenous leukemia.
    American journal of hematology, 2014, Volume: 89, Issue:10

    Topics: Adult; Aged; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Core Binding Factors; Cytarabine; Disease-Free Survival; Female; Gemtuzumab; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Survival Rate; Vidarabine

2014
Acquired factor VII deficiency associated with acute myeloid leukemia.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2015, Volume: 26, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Autoantibodies; Bacteremia; Cytarabine; Daunorubicin; Factor VII; Factor VII Deficiency; Fatal Outcome; Granulocytes; Hematoma; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Pseudomonas Infections

2015
Role of induction and consolidation chemotherapy in elderly acute myeloid leukemia patients.
    International journal of hematology, 2014, Volume: 100, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Female; Humans; Idarubicin; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Retrospective Studies; Salvage Therapy; Survival Analysis; Treatment Outcome; Vidarabine

2014
NT5C3 polymorphisms and outcome of first induction chemotherapy in acute myeloid leukemia.
    Pharmacogenetics and genomics, 2014, Volume: 24, Issue:9

    Topics: 5'-Nucleotidase; Antimetabolites, Antineoplastic; Cytarabine; Female; Genetic Association Studies; Genetic Variation; Genotype; Glycoproteins; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Polymorphism, Single Nucleotide; Republic of Korea; Treatment Outcome

2014
Association of ABCB1 polymorphisms with the efficacy of ondansetron in chemotherapy-induced nausea and vomiting.
    Clinical therapeutics, 2014, Aug-01, Volume: 36, Issue:8

    Topics: Adolescent; Adult; Alleles; Antiemetics; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B; Cytarabine; Cytochrome P-450 CYP2D6; Drug Resistance; Female; Haplotypes; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Nausea; Ondansetron; Polymorphism, Single Nucleotide; Vomiting; Young Adult

2014
[Effect of intermediate-dose cytarabine on mobilization of peripheral blood hematopoietic stem cell in acute myeloid leukemia].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2014, Volume: 35, Issue:7

    Topics: Adolescent; Adult; Child; Cytarabine; Female; Hematopoietic Stem Cell Mobilization; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Peripheral Blood Stem Cell Transplantation; Retrospective Studies; Treatment Outcome; Young Adult

2014
[Efficacy of FLAG as initial induction chemotherapy followed by autologous hematopoietic stem cell transplantation after IBu conditioning regimen in acute myeloid leukemia with FLT3 mutations].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2014, Volume: 35, Issue:7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; fms-Like Tyrosine Kinase 3; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Transplantation Conditioning; Transplantation, Autologous; Treatment Outcome; Vidarabine

2014
Incidence of and risk factors for involvement of the central nervous system in acute myeloid leukemia.
    Leukemia & lymphoma, 2015, Volume: 56, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cytarabine; Female; Humans; Incidence; Leukemia, Myeloid, Acute; Male; Middle Aged; Odds Ratio; Prognosis; Risk Factors; Survival Analysis; Young Adult

2015
Using RNA-seq and targeted nucleases to identify mechanisms of drug resistance in acute myeloid leukemia.
    Scientific reports, 2014, Aug-13, Volume: 4

    Topics: 3T3 Cells; Animals; Antimetabolites, Antineoplastic; Base Sequence; Cell Line, Tumor; Clustered Regularly Interspaced Short Palindromic Repeats; Cytarabine; Drug Resistance, Neoplasm; High-Throughput Nucleotide Sequencing; Leukemia, Myeloid, Acute; Mice; Protein Serine-Threonine Kinases; RNA Interference; RNA, Small Interfering; Sequence Analysis, RNA

2014
When the eye gives it all: diagnosis of relapsing acute myeloblastic leukemia with anterior chamber tap of a chronic hypopyon.
    American journal of hematology, 2014, Volume: 89, Issue:8

    Topics: Adult; Anterior Chamber; Antimetabolites, Antineoplastic; Cytarabine; Humans; Iridectomy; Iris; Karyotyping; Leukemia, Myeloid, Acute; Male; Recurrence

2014
Prognostic and biologic significance of DNMT3B expression in older patients with cytogenetically normal primary acute myeloid leukemia.
    Leukemia, 2015, Volume: 29, Issue:3

    Topics: Age Factors; Aged; Aged, 80 and over; Cytarabine; Daunorubicin; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; Female; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Humans; Induction Chemotherapy; Karyotyping; Leukemia, Myeloid, Acute; Male; Microarray Analysis; MicroRNAs; Middle Aged; Prognosis; Survival Analysis

2015
Granulocyte colony-stimulating factor combined regimen in cord blood transplantation for acute myeloid leukemia: a nationwide retrospective analysis in Japan.
    Haematologica, 2014, Volume: 99, Issue:12

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cord Blood Stem Cell Transplantation; Cyclophosphamide; Cytarabine; Female; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Humans; Japan; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Staging; Prognosis; Retrospective Studies; Survival Rate; Whole-Body Irradiation; Young Adult

2014
Rapid in-vitro testing for chemotherapy sensitivity in leukaemia patients.
    Advances in biochemical engineering/biotechnology, 2014, Volume: 145

    Topics: Antimetabolites, Antineoplastic; Arabinofuranosylcytosine Triphosphate; Biological Assay; Biosensing Techniques; Cell Line, Tumor; Cytarabine; Drug Screening Assays, Antitumor; Escherichia coli; Genes, Reporter; Genetic Engineering; Humans; Leukemia, Myeloid, Acute; Limit of Detection; Luciferases, Bacterial; Luminescent Measurements; Operon; Phosphorylation

2014
Takotsubo cardiomyopathy after systemic consolidation therapy with high-dose intravenous cytarabine in a patient with acute myeloid leukemia.
    Oncology research and treatment, 2014, Volume: 37, Issue:9

    Topics: Antimetabolites, Antineoplastic; Consolidation Chemotherapy; Cytarabine; Humans; Injections, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged; Takotsubo Cardiomyopathy; Treatment Outcome

2014
Chemotherapy drug shortages in the United States revisited.
    Journal of oncology practice, 2014, Volume: 10, Issue:5

    Topics: Antineoplastic Agents; Cytarabine; Drug Industry; Health Care Rationing; Health Services Accessibility; Leukemia, Myeloid, Acute; Medicare; United States; United States Food and Drug Administration

2014
Cytarabine preferentially induces mutation at specific sequences in the genome which are identifiable in relapsed acute myeloid leukaemia.
    Leukemia, 2015, Volume: 29, Issue:2

    Topics: Algorithms; Antimetabolites, Antineoplastic; Cell Line, Tumor; Cytarabine; DNA Mutational Analysis; Humans; Leukemia, Myeloid, Acute; Monte Carlo Method; Mutation; Neoplasm Recurrence, Local; Remission Induction

2015
[Neoplastic mastocytosis evolving from a poor prognosis acute myeloid leukemia].
    Medicina clinica, 2015, Jun-22, Volume: 144, Issue:12

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease Progression; Drug Resistance, Neoplasm; Fatal Outcome; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Immunophenotyping; Leukemia, Mast-Cell; Leukemia, Myeloid, Acute; Mast Cells; Mutation; Neoplasm Proteins; Neoplastic Stem Cells; Prognosis; Vidarabine

2015
Low-dose cytarabine, aclarubicin and granulocyte colony-stimulating factor priming regimen versus idarubicin plus cytarabine regimen as induction therapy for older patients with acute myeloid leukemia.
    Leukemia & lymphoma, 2015, Volume: 56, Issue:6

    Topics: Aclarubicin; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Retrospective Studies; Survival Rate

2015
[Comparing BFA with BuCyA as a myeloablative conditioning regimen for allogeneic stem cell transplantation in acute leukemias].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2014, Volume: 45, Issue:4

    Topics: Acute Disease; Busulfan; Cyclophosphamide; Cytarabine; Graft vs Host Disease; Humans; Leukemia, Myeloid, Acute; Remission Induction; Stem Cell Transplantation; Transplantation Conditioning; Transplantation, Homologous; Vidarabine

2014
Haploidentical peripheral blood stem cell infusion in combination with chemotherapy for acute myeloid leukaemia in elderly patients.
    Internal medicine journal, 2014, Volume: 44, Issue:10

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Prognosis; Prospective Studies; Treatment Outcome

2014
Pharmacodynamics of cytarabine induced leucopenia: a retrospective cohort study.
    British journal of clinical pharmacology, 2015, Volume: 79, Issue:4

    Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Cohort Studies; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Leukocyte Count; Leukopenia; Male; Middle Aged; Retrospective Studies; Young Adult

2015
Salvage therapy with ARA-C and gemtuzumab ozogamicin in AML patients relapsing after stem cell transplantation.
    Annals of hematology, 2015, Volume: 94, Issue:3

    Topics: Adult; Aminoglycosides; Antibodies, Monoclonal, Humanized; Cytarabine; Feasibility Studies; Female; Gemtuzumab; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Retrospective Studies; Salvage Therapy; Transplantation, Homologous; Treatment Failure

2015
Obatoclax potentiates the cytotoxic effect of cytarabine on acute myeloid leukemia cells by enhancing DNA damage.
    Molecular oncology, 2015, Volume: 9, Issue:2

    Topics: Antimetabolites, Antineoplastic; Child; Child, Preschool; Cytarabine; DNA Damage; Female; Humans; Indoles; Leukemia, Myeloid, Acute; Male; Pyrroles; U937 Cells

2015
Cellular intrinsic mechanism affecting the outcome of AML treated with Ara-C in a syngeneic mouse model.
    PloS one, 2014, Volume: 9, Issue:10

    Topics: Animals; Antimetabolites, Antineoplastic; Biphenyl Compounds; Cell Line, Tumor; Cytarabine; Disease Models, Animal; Down-Regulation; Drug Resistance, Neoplasm; Gene Expression Profiling; Inhibitor of Apoptosis Proteins; Leukemia, Myeloid, Acute; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Nitrophenols; Piperazines; Sulfonamides; Survival Rate; Transplantation, Homologous; Up-Regulation

2014
[Clinical efficacy of decitabine combined with modified CAG regimen for relapsed-refractory acute myeloid leukemia with AML1-ETO⁺].
    Zhongguo shi yan xue ye xue za zhi, 2014, Volume: 22, Issue:5

    Topics: Aclarubicin; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Core Binding Factor Alpha 2 Subunit; Cytarabine; Decitabine; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Oncogene Proteins, Fusion; Recurrence; Retrospective Studies; RUNX1 Translocation Partner 1 Protein; Treatment Outcome; Young Adult

2014
[Clinical curative efficacy of inducing remission for the newly diagnosed aged AML patients by chemotherapy with IA and DA regimens].
    Zhongguo shi yan xue ye xue za zhi, 2014, Volume: 22, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Retrospective Studies

2014
[Clinical analysis of reduced conditioning intensity allo-HSCT treatment for relapsed ETO-positive AML].
    Zhongguo shi yan xue ye xue za zhi, 2014, Volume: 22, Issue:5

    Topics: Adolescent; Adult; Allografts; Cytarabine; Disease-Free Survival; Erythropoietin; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Transplantation Conditioning; Vidarabine; Young Adult

2014
Effect of cytosine arabinoside metabolizing enzyme expression on drug toxicity in acute myeloid leukemia.
    Annals of hematology, 2015, Volume: 94, Issue:5

    Topics: Adult; Cytarabine; Cytidine Deaminase; Deoxycytidine Kinase; Humans; Leukemia, Myeloid, Acute; Male

2015
[The clinical efficacy of the patients of acute myeloid leukemia and myelodysplastic syndromes treated with decitabine alone, combined with half or one couse of CAG regimen].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2014, Volume: 35, Issue:11

    Topics: Aclarubicin; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Decitabine; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes

2014
[The comparative study of the effects between modified FLAG and CAG on relapsed or refractory acute myeloid leukemia].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2014, Volume: 35, Issue:11

    Topics: Aclarubicin; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Recurrence

2014
Eccrine poromatosis in a patient with acute myeloid leukemia following chemotherapy.
    Dermatology online journal, 2014, Nov-15, Volume: 20, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Poroma; Stem Cell Transplantation; Sweat Gland Neoplasms

2014
The protein kinase C agonist prostratin induces differentiation of human myeloid leukemia cells and enhances cellular differentiation by chemotherapeutic agents.
    Cancer letters, 2015, Jan-28, Volume: 356, Issue:2 Pt B

    Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Cycle; Cell Differentiation; Cell Proliferation; Cytarabine; Drug Synergism; Extracellular Signal-Regulated MAP Kinases; Humans; Leukemia, Myeloid, Acute; Phorbol Esters; Protein Kinase C; Proto-Oncogene Proteins c-myc; Tumor Cells, Cultured

2015
Minimal residual disease monitored after induction therapy by RQ-PCR can contribute to tailor treatment of patients with t(8;21) RUNX1-RUNX1T1 rearrangement.
    Haematologica, 2015, Volume: 100, Issue:3

    Topics: Antineoplastic Agents; Biomarkers, Tumor; Child; Child, Preschool; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Core Binding Factor Alpha 2 Subunit; Cytarabine; Drug Monitoring; Etoposide; Female; Humans; Idarubicin; Induction Chemotherapy; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Male; Mutation; Neoplasm, Residual; Proto-Oncogene Proteins; RUNX1 Translocation Partner 1 Protein; Survival Analysis; Transcription Factors; Translocation, Genetic

2015
Retrospective comparison of fludarabine in combination with intermediate-dose cytarabine versus high-dose cytarabine as consolidation therapies for acute myeloid leukemia.
    Medicine, 2014, Volume: 93, Issue:27

    Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Consolidation Chemotherapy; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Retrospective Studies; Vidarabine; Young Adult

2014
Possible benefit of consolidation therapy with high-dose cytarabine on overall survival of adults with non-promyelocytic acute myeloid leukemia.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2015, Volume: 48, Issue:2

    Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Cause of Death; Consolidation Chemotherapy; Cytarabine; Disease-Free Survival; Female; Humans; Karyotyping; Leukemia, Myeloid, Acute; Male; Medical Records; Middle Aged; Multivariate Analysis; Retrospective Studies; Survival Rate; Young Adult

2015
Long term maintenance of myeloid leukemic stem cells cultured with unrelated human mesenchymal stromal cells.
    Stem cell research, 2015, Volume: 14, Issue:1

    Topics: ADP-ribosyl Cyclase 1; Animals; Antigens, CD34; Antimetabolites, Antineoplastic; Apoptosis; Cells, Cultured; Coculture Techniques; Cytarabine; Humans; Immunophenotyping; Interleukin-3; Karyotyping; Leukemia, Myeloid, Acute; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Knockout; Neoplastic Stem Cells; Stem Cell Factor

2015
Proteolytic systems and AMP-activated protein kinase are critical targets of acute myeloid leukemia therapeutic approaches.
    Oncotarget, 2015, Oct-13, Volume: 6, Issue:31

    Topics: AMP-Activated Protein Kinases; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Cell Survival; Cytarabine; DNA Damage; Dose-Response Relationship, Drug; Doxorubicin; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Molecular Targeted Therapy; Peptide Hydrolases; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Kinase Inhibitors; Proteolysis; Signal Transduction; Time Factors

2015
[Progress of study on drug therapy in adults patients with acute myeloid leukemia (non APL) after remission].
    Zhongguo shi yan xue ye xue za zhi, 2014, Volume: 22, Issue:6

    Topics: Cytarabine; Disease-Free Survival; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Remission Induction; Treatment Outcome

2014
[Characteristics and treatment outcomes in 822 adult patients with acute myeloid leukemia:a single center experience].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2014, Volume: 35, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; China; Cytarabine; Disease-Free Survival; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Middle Aged; Oncogene Proteins, Fusion; Retrospective Studies; Survival Rate; Treatment Outcome; Young Adult

2014
Treatment of elderly patients with acute myeloid leukemia with azacitidine results in fewer hospitalization days and infective complications but similar survival compared with intensive chemotherapy.
    Asia-Pacific journal of clinical oncology, 2015, Volume: 11, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Female; Follow-Up Studies; Hospitalization; Humans; Idarubicin; Infections; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Staging; Retrospective Studies; Survival Rate; Treatment Outcome

2015
The OPN gene polymorphism confers the susceptibility and response to Ara-C based chemotherapy in Chinese AML patients.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2015, Volume: 35, Issue:1

    Topics: Adult; Alleles; Antimetabolites, Antineoplastic; Apoptosis; Cell Line, Tumor; China; Cytarabine; Disease Susceptibility; Female; Genotype; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Osteopontin; Polymorphism, Single Nucleotide; Transfection

2015
Expression of microRNA-331 can be used as a predictor for response to therapy and survival in acute myeloid leukemia patients.
    Biomarkers in medicine, 2015, Volume: 9, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Leukemia, Myeloid, Acute; Male; MicroRNAs; Middle Aged; Prognosis; Reverse Transcriptase Polymerase Chain Reaction; Young Adult

2015
Long-term outcomes for patients with acute myeloid leukemia: a single-center experience from AIIMS, India.
    Asia-Pacific journal of clinical oncology, 2015, Volume: 11, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Daunorubicin; Female; Humans; India; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Survival Rate; Treatment Outcome; Young Adult

2015
[Clinical resarch of decitabine combined with modified CAG regimen for treatment of relapsed or refractory acute myeloid leukemia].
    Zhongguo shi yan xue ye xue za zhi, 2015, Volume: 23, Issue:1

    Topics: Aclarubicin; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Decitabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Remission Induction; Retrospective Studies; Treatment Outcome; Young Adult

2015
High-dose cytarabine as salvage therapy for relapsed or refractory acute myeloid leukemia--is more better or more of the same?
    Hematological oncology, 2016, Volume: 34, Issue:1

    Topics: Adolescent; Adult; Allografts; Antimetabolites, Antineoplastic; Combined Modality Therapy; Cytarabine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Dyspnea; Female; Gastrointestinal Diseases; Hematopoietic Stem Cell Transplantation; Humans; Infections; Kaplan-Meier Estimate; Keratitis; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Remission Induction; Retrospective Studies; Salvage Therapy; Treatment Outcome; Xerophthalmia; Young Adult

2016
Feasibility and efficacy of outpatient therapy with intermediate dose cytarabine, fludarabine and idarubicin for patients with acute myeloid leukaemia aged 70 or older.
    European journal of haematology, 2015, Volume: 95, Issue:6

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Female; Follow-Up Studies; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Survival Analysis; Treatment Outcome; Vidarabine

2015
Anti-leukemic effect of sodium metaarsenite (KML001) in acute myeloid leukemia with breaking-down the resistance of cytosine arabinoside.
    International journal of oncology, 2015, Volume: 46, Issue:5

    Topics: Antimetabolites, Antineoplastic; Arsenites; Cell Line, Tumor; Cytarabine; Drug Resistance, Neoplasm; Enzyme Inhibitors; Humans; Leukemia, Myeloid, Acute; Real-Time Polymerase Chain Reaction; Sodium Compounds

2015
CD127+ innate lymphoid cells are dysregulated in treatment naïve acute myeloid leukemia patients at diagnosis.
    Haematologica, 2015, Volume: 100, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents; Case-Control Studies; Cell Lineage; Cytarabine; Daunorubicin; Female; Gene Expression; Humans; Immunity, Innate; Immunophenotyping; Interferon-gamma; Interleukin-7 Receptor alpha Subunit; Interleukins; Leukemia, Myeloid, Acute; Lymphocytes; Male; Middle Aged; Treatment Outcome; Tumor Necrosis Factor-alpha

2015
Arginine dependence of acute myeloid leukemia blast proliferation: a novel therapeutic target.
    Blood, 2015, Apr-09, Volume: 125, Issue:15

    Topics: Adolescent; Aged; Animals; Antimetabolites, Antineoplastic; Arginase; Arginine; Child; Child, Preschool; Cytarabine; Enzyme Therapy; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Mice, SCID; Middle Aged; Recombinant Proteins; Tumor Cells, Cultured; Young Adult

2015
Single nucleotide polymorphisms of cytarabine metabolic genes influence clinical outcome in acute myeloid leukemia patients receiving high-dose cytarabine therapy.
    International journal of hematology, 2015, Volume: 101, Issue:6

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Cytarabine; Female; Genotype; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Polymorphism, Single Nucleotide; Treatment Outcome; Young Adult

2015
INPP4B overexpression is associated with poor clinical outcome and therapy resistance in acute myeloid leukemia.
    Leukemia, 2015, Volume: 29, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Cell Proliferation; Chemoradiotherapy; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Female; Fluorescent Antibody Technique; fms-Like Tyrosine Kinase 3; Follow-Up Studies; Humans; Immunoenzyme Techniques; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Neoplasm Staging; Nucleophosmin; Phosphoric Monoester Hydrolases; Prognosis; Radiation, Ionizing; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Survival Rate; Tandem Repeat Sequences; Tumor Cells, Cultured; Young Adult

2015
CDK4/6 Inhibitor PD 0332991 Sensitizes Acute Myeloid Leukemia to Cytarabine-Mediated Cytotoxicity.
    Cancer research, 2015, May-01, Volume: 75, Issue:9

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Cytarabine; DNA Damage; DNA Replication; HEK293 Cells; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Mice, Inbred NOD; Mice, SCID; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-pim-1; Pyridines; S Phase; Transcription, Genetic; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2015
Upregulation of microRNA-126-5p is associated with drug resistance to cytarabine and poor prognosis in AML patients.
    Oncology reports, 2015, Volume: 33, Issue:5

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Blotting, Western; Cytarabine; Drug Resistance, Neoplasm; Female; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; MicroRNAs; Middle Aged; Prognosis; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Up-Regulation; Young Adult

2015
Comparison of administrative/billing data to expected protocol-mandated chemotherapy exposure in children with acute myeloid leukemia: A report from the Children's Oncology Group.
    Pediatric blood & cancer, 2015, Volume: 62, Issue:7

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child Health Services; Child, Preschool; Comparative Effectiveness Research; Cytarabine; Daunorubicin; Etoposide; Female; Follow-Up Studies; Health Information Systems; Hospitals, Pediatric; Humans; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Male; Outcome and Process Assessment, Health Care; Young Adult

2015
Evolving treatments in acute myeloid leukemia.
    Clinical advances in hematology & oncology : H&O, 2015, Volume: 13, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Immunotherapy; Leukemia, Myeloid, Acute; Molecular Targeted Therapy

2015
[The relationship between induction chemotherapy cycles and prognosis in patients with acute myeloid leukemia].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2015, Volume: 36, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Cytogenetics; Disease-Free Survival; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Prognosis; Remission Induction

2015
Cytarabine, venous catheter removal, sepsis, diagnosis of malignancy, and takotsubo syndrome.
    Oncology research and treatment, 2015, Volume: 38, Issue:3

    Topics: Consolidation Chemotherapy; Cytarabine; Humans; Leukemia, Myeloid, Acute; Male; Takotsubo Cardiomyopathy

2015
"Cup-like" blasts in acute myeloid leukemia with FLT3 and NPM1 mutations.
    Blood, 2015, Jan-29, Volume: 125, Issue:5

    Topics: Antineoplastic Agents; Bone Marrow Cells; Cytarabine; fms-Like Tyrosine Kinase 3; Humans; Idarubicin; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Nuclear Proteins; Nucleophosmin

2015
Comparison of epigenetic versus standard induction chemotherapy for newly diagnosed acute myeloid leukemia patients ≥60 years old.
    American journal of hematology, 2015, Volume: 90, Issue:7

    Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Cytarabine; Decitabine; Epigenesis, Genetic; Female; fms-Like Tyrosine Kinase 3; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Mutation; Nuclear Proteins; Nucleophosmin; Remission Induction; Retrospective Studies; Survival Analysis; Treatment Outcome

2015
Risk factors for cytarabine-induced cutaneous toxicity in patients with haematological malignancies.
    Chemotherapy, 2014, Volume: 60, Issue:3

    Topics: Cytarabine; Female; Hematologic Neoplasms; Humans; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Middle Aged; Retrospective Studies; Risk Factors; Skin Diseases

2014
Lethal toxicity after administration of azacytidine: implication of the cytidine deaminase-deficiency syndrome.
    Pharmacogenetics and genomics, 2015, Volume: 25, Issue:6

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Cytarabine; Cytidine Deaminase; Deoxycytidine; Fatal Outcome; Gemcitabine; Humans; Inactivation, Metabolic; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Polymorphism, Single Nucleotide

2015
[Comparison of 10 mg/m² or 8 mg/m² idarubicin plus cytarabine regimen as induction chemotherapy for adult patients with newly diagnosed acute myeloid leukemia].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2015, Volume: 36, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Prognosis; Remission Induction

2015
Mutational cooperativity linked to combinatorial epigenetic gain of function in acute myeloid leukemia.
    Cancer cell, 2015, Apr-13, Volume: 27, Issue:4

    Topics: Antineoplastic Agents; Cell Differentiation; Cytarabine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Doxorubicin; Epigenesis, Genetic; fms-Like Tyrosine Kinase 3; GATA2 Transcription Factor; Gene Expression Regulation, Neoplastic; Gene Silencing; Haploinsufficiency; Leukemia, Myeloid, Acute; Mutation; Proto-Oncogene Proteins

2015
Decreased invasive fungal disease but no impact on overall survival by posaconazole compared to fluconazole prophylaxis: a retrospective cohort study in patients receiving induction therapy for acute myeloid leukaemia/myelodysplastic syndromes.
    European journal of haematology, 2016, Volume: 96, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Fluconazole; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Mycoses; Myelodysplastic Syndromes; Pre-Exposure Prophylaxis; Remission Induction; Retrospective Studies; Survival Analysis; Triazoles

2016
The HSP90 inhibitor ganetespib: A potential effective agent for Acute Myeloid Leukemia in combination with cytarabine.
    Leukemia research, 2015, Volume: 39, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Cytarabine; Dose-Response Relationship, Drug; Female; HL-60 Cells; HSP90 Heat-Shock Proteins; Humans; Leukemia, Myeloid, Acute; Male; Proto-Oncogene Proteins c-akt; Triazoles

2015
Targeting of FLT3-ITD kinase contributes to high selectivity of imidazoacridinone C-1311 against FLT3-activated leukemia cells.
    Biochemical pharmacology, 2015, Jun-15, Volume: 95, Issue:4

    Topics: Aminoacridines; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Survival; Cytarabine; Doxorubicin; Drug Synergism; Enzyme Activation; fms-Like Tyrosine Kinase 3; Humans; Inhibitor of Apoptosis Proteins; Leukemia, Myeloid, Acute; Mutation; Phosphorylation; RNA, Small Interfering; Signal Transduction; Survivin

2015
Two cases of cytarabine syndrome successfully resolved by desensitization.
    Journal of investigational allergology & clinical immunology, 2015, Volume: 25, Issue:1

    Topics: Aged; Antimetabolites, Antineoplastic; Chills; Cytarabine; Desensitization, Immunologic; Drug-Related Side Effects and Adverse Reactions; Female; Fever; Humans; Hypotension; Leukemia, Myeloid, Acute; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Shivering; Syndrome

2015
Oncogenic NRAS Primes Primary Acute Myeloid Leukemia Cells for Differentiation.
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Aged; Cell Differentiation; Cell Line, Tumor; Cohort Studies; Cytarabine; Female; Gene Expression Regulation, Neoplastic; GTP Phosphohydrolases; Homeodomain Proteins; Humans; Leukemia, Myeloid, Acute; Male; Membrane Proteins; Middle Aged; Mutation; Myeloid Cells; Myeloid Ecotropic Viral Integration Site 1 Protein; Neoplasm Proteins; Oncogene Proteins, Fusion; ras Proteins

2015
[Cohort Study on GHA and New Combined Priming Chemotherapeutic Regimens in Treatment of Refractory Acute Myeloid Leukemia and Myelodysplastic Syndrome].
    Zhongguo shi yan xue ye xue za zhi, 2015, Volume: 23, Issue:2

    Topics: Aclarubicin; Antineoplastic Combined Chemotherapy Protocols; B7-1 Antigen; Cohort Studies; Cytarabine; Doxorubicin; Granulocyte Colony-Stimulating Factor; Granulocytes; Harringtonines; Homoharringtonine; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Recurrence; Thrombocytopenia

2015
[Efficacy Analysis of MAC Regimen as Salvage Treatment Protocol for Acute Myeloid Leukemia Patients Older Than 55 Years].
    Zhongguo shi yan xue ye xue za zhi, 2015, Volume: 23, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cytarabine; Dactinomycin; Humans; Leukemia, Myeloid, Acute; Methotrexate; Middle Aged; Recurrence; Remission Induction; Salvage Therapy

2015
Concentrative nucleoside transporter 3 as a prognostic indicator for favorable outcome of t(8;21)-positive acute myeloid leukemia patients after cytarabine-based chemotherapy.
    Oncology reports, 2015, Volume: 34, Issue:1

    Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Membrane Transport Proteins; Middle Aged; Survival Analysis; Translocation, Genetic; Treatment Outcome; Up-Regulation; Young Adult

2015
Cytarabine, venous catheter removal, sepsis, diagnosis of malignancy, and takotsubo syndrome. Reply by Baumann et al.
    Oncology research and treatment, 2015, Volume: 38, Issue:3

    Topics: Consolidation Chemotherapy; Cytarabine; Humans; Leukemia, Myeloid, Acute; Male; Takotsubo Cardiomyopathy

2015
Increasing aclarubicin dose in low-dose cytarabine and aclarubicin in combination with granulocyte colony-stimulating factor (CAG regimen) is efficacious as salvage chemotherapy for relapsed/refractory mixed-phenotype acute leukemia.
    Leukemia research, 2015, Volume: 39, Issue:8

    Topics: Aclarubicin; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Recurrence; Retrospective Studies; Salvage Therapy; Treatment Outcome; Vincristine; Young Adult

2015
Development and molecular characterization of polymeric micro-nanofibrous scaffold of a defined 3-D niche for in vitro chemosensitivity analysis against acute myeloid leukemia cells.
    International journal of nanomedicine, 2015, Volume: 10

    Topics: Biphenyl Compounds; Cell Adhesion; Cell Proliferation; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Fibronectins; Humans; Lactic Acid; Leukemia, Myeloid, Acute; Nanocomposites; Nanofibers; Nitrophenols; Piperazines; Polyesters; Polymers; Polyurethanes; Sulfonamides; Tissue Scaffolds

2015
Guidelines for the diagnosis and management of acute myeloid leukaemia in pregnancy.
    British journal of haematology, 2015, Volume: 170, Issue:4

    Topics: Amphotericin B; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Delivery, Obstetric; Female; Humans; Leukemia, Myeloid, Acute; Pregnancy; Pregnancy Complications, Neoplastic

2015
RNA expression of genes involved in cytarabine metabolism and transport predicts cytarabine response in acute myeloid leukemia.
    Pharmacogenomics, 2015, Volume: 16, Issue:8

    Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Apoptosis; Cytarabine; Cytidine Deaminase; Daunorubicin; Deoxycytidine Kinase; Disease-Free Survival; Drug Resistance, Neoplasm; Equilibrative Nucleoside Transporter 1; Female; Gene Expression Regulation, Leukemic; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Ribonucleoside Diphosphate Reductase; Tumor Suppressor Proteins

2015
MK-2206 induces apoptosis of AML cells and enhances the cytotoxicity of cytarabine.
    Medical oncology (Northwood, London, England), 2015, Volume: 32, Issue:7

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; Cell Proliferation; Cytarabine; Down-Regulation; Drug Synergism; G1 Phase; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Heterocyclic Compounds, 3-Ring; Humans; Leukemia, Myeloid, Acute; Leukocytes, Mononuclear; Myeloid Cell Leukemia Sequence 1 Protein; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; U937 Cells

2015
Effects of changes in serum endostatin and fibroblast growth factor 19 on the chemotherapeutic sensitivity in acute myeloid leukemia patients.
    Genetics and molecular research : GMR, 2015, May-18, Volume: 14, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Pharmacological; Case-Control Studies; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Endostatins; Female; Fibroblast Growth Factors; Gene Expression; Harringtonines; Homoharringtonine; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Remission Induction; ROC Curve; Treatment Outcome

2015
Efficacy of an Fc-modified anti-CD123 antibody (CSL362) combined with chemotherapy in xenograft models of acute myelogenous leukemia in immunodeficient mice.
    Haematologica, 2015, Volume: 100, Issue:7

    Topics: Adoptive Transfer; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Cytarabine; Daunorubicin; Female; Gene Expression; Humans; Immunocompromised Host; Immunoglobulin Fc Fragments; Interleukin-3 Receptor alpha Subunit; Killer Cells, Natural; Leukemia, Myeloid, Acute; Mice; Survival Analysis; Transplantation, Heterologous; Xenograft Model Antitumor Assays

2015
High dose cytarabine, mitoxantrone and l-asparaginase (HAMA) salvage for relapsed or refractory acute myeloid leukemia (AML) in the elderly.
    Leukemia research, 2015, Volume: 39, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cytarabine; Drug Administration Schedule; Female; Hematopoietic Stem Cell Transplantation; Humans; Karyotype; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Recurrence; Remission Induction; Retrospective Studies; Salvage Therapy; Survival Analysis; Transplantation, Homologous; Treatment Outcome

2015
SPARC ectopic overexpression inhibits growth and promotes programmed cell death in acute myeloid leukemia transformed from myelodysplastic syndrome cells, alone and in combination with Ara-C treatment.
    Oncology reports, 2015, Volume: 34, Issue:3

    Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Cytarabine; Gene Expression Regulation, Leukemic; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Necrosis; Osteonectin; Protein Kinases

2015
Clinical significance of the administration of cytarabine or thiotepa in addition to total body irradiation and cyclophosphamide for allogeneic hematopoietic cell transplantation in patients with acute leukemia.
    International journal of hematology, 2015, Volume: 102, Issue:4

    Topics: Adolescent; Adult; Allografts; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Cyclophosphamide; Cytarabine; Disease-Free Survival; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Metabolic Clearance Rate; Middle Aged; Retrospective Studies; Survival Rate; Thiotepa

2015
Residual Disease in a Novel Xenograft Model of RUNX1-Mutated, Cytogenetically Normal Acute Myeloid Leukemia.
    PloS one, 2015, Volume: 10, Issue:7

    Topics: Animals; Anthracyclines; Bone Marrow; Cell Line, Tumor; Core Binding Factor Alpha 2 Subunit; Cytarabine; Cytogenetic Analysis; DNA Mutational Analysis; Exome; Humans; Leukemia, Myeloid, Acute; Mice, Inbred NOD; Mice, SCID; Mutation; Neoplasm, Residual; Xenograft Model Antitumor Assays

2015
Successful Treatment With Total Skin Electron Beam Therapy in a Child With Isolated Cutaneous Relapsed AML.
    Journal of pediatric hematology/oncology, 2015, Volume: 37, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Electrons; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Skin Diseases; Vidarabine

2015
Endothelial cell derived angiocrine support of acute myeloid leukemia targeted by receptor tyrosine kinase inhibition.
    Leukemia research, 2015, Volume: 39, Issue:9

    Topics: Animals; Antimetabolites, Antineoplastic; Bone Marrow Cells; Cell Line, Tumor; Cell Proliferation; Coculture Techniques; Cytarabine; Drug Resistance, Neoplasm; Endothelial Cells; Gene Expression Regulation, Leukemic; Human Umbilical Vein Endothelial Cells; Humans; Indazoles; Leukemia, Myeloid, Acute; Mice; Mice, SCID; Neoplasm Transplantation; Neovascularization, Pathologic; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrimidines; Receptors, Platelet-Derived Growth Factor; Receptors, Vascular Endothelial Growth Factor; Signal Transduction; Sulfonamides; Tumor Burden; Vascular Endothelial Growth Factor A

2015
Antileukemic Activity of 2-Deoxy-d-Glucose through Inhibition of N-Linked Glycosylation in Acute Myeloid Leukemia with FLT3-ITD or c-KIT Mutations.
    Molecular cancer therapeutics, 2015, Volume: 14, Issue:10

    Topics: Animals; Antineoplastic Agents; Apoptosis; Benzothiazoles; Biphenyl Compounds; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytarabine; Deoxyglucose; Drug Resistance, Neoplasm; fms-Like Tyrosine Kinase 3; Glycolysis; Glycosylation; Humans; Leukemia, Myeloid, Acute; Mice, Inbred NOD; Mice, SCID; Mutation; Myeloid Cell Leukemia Sequence 1 Protein; Nitrophenols; Phenylurea Compounds; Piperazines; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-kit; Signal Transduction; Sulfonamides; Xenograft Model Antitumor Assays

2015
Induction of cytosine arabinoside-resistant human myeloid leukemia cell death through autophagy regulation by hydroxychloroquine.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2015, Volume: 73

    Topics: Antimetabolites, Antineoplastic; Autophagy; Cell Death; Cytarabine; Drug Resistance, Neoplasm; Humans; Hydroxychloroquine; Leukemia, Myeloid, Acute; U937 Cells

2015
Heme oxygenase-1 plays a crucial role in chemoresistance in acute myeloid leukemia.
    Hematology (Amsterdam, Netherlands), 2015, Volume: 20, Issue:7

    Topics: Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Female; Heme Oxygenase-1; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Male; Neoplasm Proteins; U937 Cells

2015
N-(2-Hydroxypropyl)methacrylamide Copolymer-Drug Conjugates for Combination Chemotherapy of Acute Myeloid Leukemia.
    Macromolecular bioscience, 2016, Volume: 16, Issue:1

    Topics: Acrylamides; Bridged Bicyclo Compounds, Heterocyclic; Cell Cycle; Cytarabine; Daunorubicin; Drug Carriers; Drug Synergism; Drug Therapy, Combination; Female; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Pyrimidines

2016
Outcomes for newly diagnosed patients with acute myeloid leukemia dosed on actual or adjusted body weight.
    Cancer chemotherapy and pharmacology, 2015, Volume: 76, Issue:4

    Topics: Adult; Aged; Anthracyclines; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Body Mass Index; Body Weight; Cohort Studies; Cytarabine; Drug Dosage Calculations; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Obesity; Overweight; Recurrence; Remission Induction; Retrospective Studies; Young Adult

2015
Vosaroxin in acute myeloid leukaemia.
    The Lancet. Oncology, 2015, Volume: 16, Issue:9

    Topics: Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Naphthyridines; Neoplasm Recurrence, Local; Thiazoles

2015
Depletion of the chromatin remodeler CHD4 sensitizes AML blasts to genotoxic agents and reduces tumor formation.
    Blood, 2015, Sep-17, Volume: 126, Issue:12

    Topics: Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Autoantigens; Cell Line, Tumor; Cytarabine; Daunorubicin; DNA Breaks, Double-Stranded; Female; Humans; Leukemia, Myeloid, Acute; Mi-2 Nucleosome Remodeling and Deacetylase Complex; Mice, Inbred NOD; Mice, SCID; RNA Interference; Tumor Cells, Cultured

2015
Synergism of Curcumin and Cytarabine in the Down Regulation of Multi-Drug Resistance Genes in Acute Myeloid Leukemia.
    Anti-cancer agents in medicinal chemistry, 2016, Volume: 16, Issue:1

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Line, Tumor; Cell Proliferation; Cell Survival; Curcumin; Cytarabine; Dose-Response Relationship, Drug; Down-Regulation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Neoplasm Proteins; Real-Time Polymerase Chain Reaction; Structure-Activity Relationship; Vault Ribonucleoprotein Particles

2016
Oncogene- and drug resistance-associated alternative exon usage in acute myeloid leukemia (AML).
    Oncotarget, 2016, Jan-19, Volume: 7, Issue:3

    Topics: Aged; Alternative Splicing; Anthracyclines; Antineoplastic Agents; Azacitidine; Cell Line, Tumor; Chromosomal Proteins, Non-Histone; Cytarabine; Doxorubicin; Drug Resistance, Neoplasm; Exons; Gene Expression Profiling; HEK293 Cells; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Oncogene Proteins; Oncogenes; Poly-ADP-Ribose Binding Proteins; RNA Interference; RNA, Small Interfering; WT1 Proteins

2016
Bone Marrow MicroRNA-335 Level Predicts the Chemotherapy Response and Prognosis of Adult Acute Myeloid Leukemia.
    Medicine, 2015, Volume: 94, Issue:33

    Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Female; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; MicroRNAs; Middle Aged; Prognosis; Survival Analysis; Treatment Outcome

2015
Association Between Mutation Clearance After Induction Therapy and Outcomes in Acute Myeloid Leukemia.
    JAMA, 2015, Aug-25, Volume: 314, Issue:8

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Genome, Human; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; MicroRNAs; Middle Aged; Mutation; Outcome Assessment, Health Care; Polymorphism, Genetic; Prognosis; Recurrence; RNA, Messenger; Sequence Analysis, RNA

2015
Lipid Nanosystems Enhance the Bioavailability and the Therapeutic Efficacy of FTY720 in Acute Myeloid Leukemia.
    Journal of biomedical nanotechnology, 2015, Volume: 11, Issue:4

    Topics: Animals; Antineoplastic Agents; Apoptosis; Caspases; Cell Proliferation; Cytarabine; Drug Delivery Systems; Enzyme Activation; Female; Fingolimod Hydrochloride; HL-60 Cells; Humans; Idarubicin; Leukemia, Myeloid, Acute; Lipids; Mice; Mice, Transgenic; Nanoparticles; Nanotechnology; Propylene Glycols; Sphingosine

2015
Limited efficacy of HLA-haploidentical peripheral blood stem cell infusion in treatment of elderly patients with acute myelogenous leukaemia.
    Hematological oncology, 2017, Volume: 35, Issue:2

    Topics: Aged; Cytarabine; Daunorubicin; Female; Histocompatibility Testing; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Peripheral Blood Stem Cell Transplantation

2017
[Clinical Efficacy of Decitabine Combined with CAG Regimen for Myelodysplastic Syndrome-RAEB and Refractory Acute Myeloid Leukemia].
    Zhongguo shi yan xue ye xue za zhi, 2015, Volume: 23, Issue:4

    Topics: Aclarubicin; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Decitabine; Granulocyte Colony-Stimulating Factor; Humans; Karyotype; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Pancytopenia; Recurrence; Remission Induction; Retrospective Studies; Survival Rate; Treatment Outcome

2015
Enhancement of arabinocytosine (AraC) toxicity to AML cells by a differentiation agent combination.
    The Journal of steroid biochemistry and molecular biology, 2016, Volume: 164

    Topics: Abietanes; Annexin A5; Antimetabolites, Antineoplastic; Antioxidants; Apoptosis; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Differentiation; Comet Assay; Cytarabine; DNA Damage; Ergocalciferols; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Phosphorylation; Propidium; U937 Cells

2016
Clinical outcomes of patients with acute myeloid leukemia: evaluation of genetic and molecular findings in a real-life setting.
    Blood, 2015, Oct-08, Volume: 126, Issue:15

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cytarabine; Cytogenetic Analysis; Etoposide; Female; fms-Like Tyrosine Kinase 3; Follow-Up Studies; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Neoplasm Staging; Nuclear Proteins; Nucleophosmin; Prognosis; Survival Rate; Thioguanine; Young Adult

2015
The impact of standard chemotherapy on miRNA signature in plasma in AML patients.
    Leukemia research, 2015, Volume: 39, Issue:12

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Consolidation Chemotherapy; Cytarabine; Female; Gene Expression Regulation, Leukemic; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; MicroRNAs; Middle Aged; Mitoxantrone; Pilot Projects; Real-Time Polymerase Chain Reaction; Remission Induction; RNA, Neoplasm; Transcriptome

2015
Cytidine deaminase polymorphisms and worse treatment response in normal karyotype AML.
    Journal of human genetics, 2015, Volume: 60, Issue:12

    Topics: Adolescent; Adult; Aged; Cytarabine; Cytidine Deaminase; Disease-Free Survival; Female; Haplotypes; Humans; Karyotype; Leukemia, Myeloid, Acute; Linkage Disequilibrium; Male; Middle Aged; Polymorphism, Genetic; Survival Rate

2015
Clinical significance of in vivo cytarabine-induced gene expression signature in AML.
    Leukemia & lymphoma, 2016, Volume: 57, Issue:4

    Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Child, Preschool; Cytarabine; Female; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Gene Knockdown Techniques; Gene Regulatory Networks; Humans; Leukemia, Myeloid, Acute; Male; Reproducibility of Results; RNA Interference; RNA, Small Interfering; Transcriptome; Treatment Outcome

2016
Epigenetic priming with decitabine followed by low-dose idarubicin/cytarabine has an increased anti-leukemic effect compared to traditional chemotherapy in high-risk myeloid neoplasms.
    Leukemia & lymphoma, 2016, Volume: 57, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Chromosome Aberrations; Cytarabine; Decitabine; Disease Progression; Drug Administration Schedule; Drug Resistance, Neoplasm; Epigenesis, Genetic; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Myelodysplastic Syndromes; Recurrence; Remission Induction; Treatment Outcome

2016
Fertility After Treatment With High Dose Melphalan in Women With Acute Myelogenous Leukemia.
    Pediatric blood & cancer, 2016, Volume: 63, Issue:2

    Topics: Adolescent; Adult; Anthracyclines; Consolidation Chemotherapy; Cytarabine; Etoposide; Female; Fertility; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Melphalan; Myeloablative Agonists; Survivors; Transplantation Conditioning; Young Adult

2016
STAT5 gene polymorphisms are associated with the response of acute myeloid leukemia patients to Ara-C-based chemotherapy.
    Leukemia & lymphoma, 2016, Volume: 57, Issue:4

    Topics: Adult; Aged; Alleles; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Genotype; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Polymorphism, Single Nucleotide; Signal Transduction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; STAT5 Transcription Factor; Treatment Outcome

2016
The hypomethylating agent decitabine prior to chemotherapy improves the therapy efficacy in refractory/relapsed acute myeloid leukemia patients.
    Oncotarget, 2015, Oct-20, Volume: 6, Issue:32

    Topics: Aclarubicin; Adolescent; Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cell Line, Tumor; Cytarabine; Decitabine; Disease-Free Survival; Female; Harringtonines; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Recurrence, Local; Treatment Outcome; Young Adult

2015
Knockdown of homeobox A5 by small hairpin RNA inhibits proliferation and enhances cytarabine chemosensitivity of acute myeloid leukemia cells.
    Molecular medicine reports, 2015, Volume: 12, Issue:5

    Topics: Antimetabolites, Antineoplastic; Cell Proliferation; Cytarabine; Drug Resistance, Neoplasm; Homeodomain Proteins; Humans; Leukemia, Myeloid, Acute; RNA Interference; RNA, Small Interfering; U937 Cells

2015
A CXCR4 antagonist leads to tumor suppression by activation of immune cells in a leukemia-induced microenvironment.
    Oncology reports, 2015, Volume: 34, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Animals; Apoptosis; Benzylamines; Bone Marrow Cells; Cell Movement; Chemokine CXCL12; Cyclams; Cytarabine; Female; Hematopoietic Stem Cells; Heterocyclic Compounds; Humans; Leukemia, Myeloid, Acute; Male; Mice; Middle Aged; Neoplasms, Experimental; Neoplastic Stem Cells; Receptors, CXCR4; Tumor Microenvironment

2015
Cytarabine syndrome despite corticosteroid premedication in an adult undergoing induction treatment for acute myelogenous leukemia.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2016, Volume: 22, Issue:6

    Topics: Adrenal Cortex Hormones; Adult; Antimetabolites, Antineoplastic; Cytarabine; Dexamethasone; Female; Fever; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Pain; Premedication; Syndrome

2016
Risk factors for outcome in refractory acute myeloid leukemia patients treated with a combination of fludarabine, cytarabine, and amsacrine followed by a reduced-intensity conditioning and allogeneic stem cell transplantation.
    Journal of cancer research and clinical oncology, 2016, Volume: 142, Issue:1

    Topics: Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Female; Follow-Up Studies; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Remission Induction; Retrospective Studies; Risk Factors; Survival Rate; Transplantation Conditioning; Transplantation, Homologous; Vidarabine; Young Adult

2016
Oral Maintenance Chemotherapy with 6-Mercaptopurine and Methotrexate in Patients with Acute Myeloid Leukemia Ineligible for Transplantation.
    Journal of Korean medical science, 2015, Volume: 30, Issue:10

    Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Maintenance Chemotherapy; Male; Mercaptopurine; Methotrexate; Middle Aged; Remission Induction; Treatment Outcome; Young Adult

2015
Increasing aclarubicin dosage of the conventional CAG (low-dose cytarabine and aclarubicin in combination with granulocyte colony-stimulating factor) regimen is more efficacious as a salvage therapy than CAG for relapsed/refractory acute myeloid leukemia.
    Leukemia research, 2015, Volume: 39, Issue:12

    Topics: Aclarubicin; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Cardiomyopathies; Chemical and Drug Induced Liver Injury; Cytarabine; Dose-Response Relationship, Drug; Female; Granulocyte Colony-Stimulating Factor; Humans; Kaplan-Meier Estimate; Kidney Diseases; Leukemia, Myeloid, Acute; Male; Middle Aged; Proportional Hazards Models; Recurrence; Remission Induction; Retrospective Studies; Salvage Therapy; Treatment Outcome; Young Adult

2015
Decitabine in the Treatment of Acute Myeloid Leukemia and Myelodysplastic Syndromes, Which Combined with Complex Karyotype Respectively.
    Asian Pacific journal of cancer prevention : APJCP, 2015, Volume: 16, Issue:15

    Topics: Abnormal Karyotype; Aclarubicin; Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Child; Child, Preschool; Cytarabine; Decitabine; Disease-Free Survival; Female; Granulocyte Colony-Stimulating Factor; Hematologic Diseases; Hematuria; Humans; Induction Chemotherapy; Infections; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Retrospective Studies; Survival Rate; Treatment Outcome; Young Adult

2015
[Clinical features and survival analysis of patients with CD56 expression in de- novo acute myeloid leukemia with t(8;21)].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2015, Volume: 36, Issue:8

    Topics: Bone Marrow; CD56 Antigen; Chromosome Aberrations; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Cytarabine; Disease-Free Survival; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Prognosis; Remission Induction; Retrospective Studies; Survival Analysis

2015
Successful use of high-dose cytarabine in a patient with acute myeloid leukemia and severe hepatic dysfunction.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2016, Volume: 22, Issue:6

    Topics: Antimetabolites, Antineoplastic; Cytarabine; Humans; Leukemia, Myeloid, Acute; Liver Diseases; Male; Middle Aged; Treatment Outcome

2016
A case of simultaneous occurrence of acute myeloid leukemia and multiple myeloma.
    BMC cancer, 2015, Oct-16, Volume: 15

    Topics: Aclarubicin; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Multiple Myeloma; Remission Induction

2015
FLT3-ITD drives Ara-C resistance in leukemic cells via the induction of RUNX3.
    Leukemia research, 2015, Volume: 39, Issue:12

    Topics: Cell Line, Tumor; Core Binding Factor Alpha 3 Subunit; Cytarabine; Drug Resistance, Neoplasm; fms-Like Tyrosine Kinase 3; Fusion Proteins, bcr-abl; Humans; K562 Cells; Leukemia, Myeloid, Acute; Neoplastic Stem Cells; Recombinant Fusion Proteins; RNA Interference; RNA, Small Interfering; Tandem Repeat Sequences; Transcription, Genetic; Transduction, Genetic

2015
Addition of Cladribine to Idarubicin and Cytarabine during Induction Increases the Overall Efficacy Rate in Adult Patients with Acute Myeloid Leukemia: A Matched-Pair Retrospective Comparison.
    Chemotherapy, 2014, Volume: 60, Issue:5-6

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cytarabine; Drug Synergism; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Retrospective Studies; Treatment Outcome; Young Adult

2014
HAG regimen improves survival in adult patients with hypocellular acute myeloid leukemia.
    Oncotarget, 2016, Jan-19, Volume: 7, Issue:3

    Topics: Adolescent; Adult; Aged; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Staging; Prognosis; Remission Induction; Retrospective Studies; Survival Rate; Young Adult

2016
Induction of Acute Myeloid Leukemia with Idarubicin, Cytarabine and Cladribine.
    Anticancer research, 2015, Volume: 35, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Staging; Prognosis; Remission Induction; Retrospective Studies; Survival Rate; Young Adult

2015
Long-term remission of therapy-related acute myeloid leukemia with a new t(11;18)(q23;q21.2) translocation and KMT2A-ME2 (MLL-ME2) fusion gene.
    Cancer genetics, 2015, Volume: 208, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Cytogenetic Analysis; Female; Granulocyte Colony-Stimulating Factor; Histone-Lysine N-Methyltransferase; Humans; Leukemia, Myeloid, Acute; Malate Dehydrogenase; Middle Aged; Myeloid-Lymphoid Leukemia Protein; Oncogene Proteins, Fusion; Salvage Therapy; Translocation, Genetic; Vidarabine

2015
Cladribine added to daunorubicin-cytarabine induction prolongs survival of FLT3-ITD+ normal karyotype AML patients.
    Blood, 2016, Jan-21, Volume: 127, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cytarabine; Daunorubicin; fms-Like Tyrosine Kinase 3; Gene Duplication; Humans; Karyotype; Leukemia, Myeloid, Acute; Treatment Outcome

2016
Clinical Impact of Additional Cytogenetic Aberrations, cKIT and RAS Mutations, and Treatment Elements in Pediatric t(8;21)-AML: Results From an International Retrospective Study by the International Berlin-Frankfurt-Münster Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Dec-20, Volume: 33, Issue:36

    Topics: Adolescent; Anthracyclines; Antineoplastic Agents; Child; Child, Preschool; Chromosome Aberrations; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Cytarabine; Disease-Free Survival; Etoposide; Female; Germany; Hematopoietic Stem Cell Transplantation; Humans; Incidence; Induction Chemotherapy; International Cooperation; Kaplan-Meier Estimate; Karyotype; Leukemia, Myeloid, Acute; Male; Molecular Targeted Therapy; Mutation; Predictive Value of Tests; Proto-Oncogene Proteins c-kit; ras Proteins; Retrospective Studies; Translocation, Genetic; Transplantation, Homologous; Treatment Outcome

2015
Deoxycytidine kinase is downregulated under hypoxic conditions and confers resistance against cytarabine in acute myeloid leukaemia.
    European journal of haematology, 2016, Volume: 97, Issue:3

    Topics: Antimetabolites, Antineoplastic; Cell Line, Tumor; Cell Proliferation; Cytarabine; Deoxycytidine Kinase; Down-Regulation; Drug Resistance, Neoplasm; Gene Expression; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Leukemia, Myeloid, Acute; Neoplastic Stem Cells

2016
Interactions Between Nutraceutical Supplements and Standard Acute Myeloid Leukemia Chemotherapeutics.
    Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 2015, Volume: 18, Issue:4

    Topics: Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cytarabine; Daunorubicin; Dietary Supplements; Drug Interactions; Humans; Leukemia, Myeloid, Acute; U937 Cells

2015
Chemoprotection of murine hematopoietic cells by combined gene transfer of cytidine deaminase (CDD) and multidrug resistance 1 gene (MDR1).
    Journal of experimental & clinical cancer research : CR, 2015, Dec-12, Volume: 34

    Topics: Animals; Anthracyclines; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytarabine; Cytidine Deaminase; DNA, Complementary; Gene Expression Regulation, Leukemic; Gene Transfer Techniques; Genetic Vectors; Hematopoietic Stem Cells; Humans; Lentivirus; Leukemia, Myeloid, Acute; Mice; Myelodysplastic Syndromes; RNA Splice Sites

2015
Inherited variation in OATP1B1 is associated with treatment outcome in acute myeloid leukemia.
    Clinical pharmacology and therapeutics, 2016, Volume: 99, Issue:6

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Cohort Studies; Cytarabine; DNA; Female; Genetic Linkage; Genetic Variation; Humans; Leukemia, Myeloid, Acute; Liver-Specific Organic Anion Transporter 1; Male; Mice; Mice, Knockout; Polymorphism, Single Nucleotide; Survival Analysis; Treatment Outcome

2016
The prevalence and clinical profiles of FLT3-ITD, FLT3-TKD, NPM1, C-KIT, DNMT3A, and CEBPA mutations in a cohort of patients with de novo acute myeloid leukemia from southwest China.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016, Volume: 37, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; CCAAT-Enhancer-Binding Proteins; China; Cytarabine; Daunorubicin; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; DNA Mutational Analysis; Female; fms-Like Tyrosine Kinase 3; Gene Frequency; Genetic Predisposition to Disease; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Neoplasm Proteins; Nuclear Proteins; Nucleophosmin; Oncogene Proteins, Fusion; Proto-Oncogene Proteins c-kit; Retrospective Studies; Treatment Outcome; Young Adult

2016
[Clinical Analysis of 4 AML Patients Aged Over 80 Years Treated with Chemotherapy Combined with Haploidentical Hematopoietic Stem Cell Infusion].
    Zhongguo shi yan xue ye xue za zhi, 2015, Volume: 23, Issue:6

    Topics: Aged, 80 and over; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Female; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Remission Induction

2015
[Sequential intensified conditioning followed by graft-versus-leukemia induction could prevent relapse of refractory acute myeloid leukemia after allogeneic hematopoietic stem cell transplantation].
    Zhonghua yi xue za zhi, 2015, Jun-23, Volume: 95, Issue:24

    Topics: Cyclophosphamide; Cytarabine; Disease-Free Survival; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Prospective Studies; Recurrence; Remission Induction; Transplantation, Homologous; Transplants; Whole-Body Irradiation

2015
Cerebral embolism through hematogenous dissemination of pulmonary mucormycosis complicating relapsed leukemia.
    International journal of clinical and experimental pathology, 2015, Volume: 8, Issue:10

    Topics: Aged; Autopsy; Cytarabine; Fatal Outcome; Female; Humans; Injections, Spinal; Intracranial Embolism; Invasive Pulmonary Aspergillosis; Leukemia, Myeloid, Acute; Lung; Methotrexate; Mucormycosis

2015
[Infliximab therapy for Crohn's-like gastrointestinal lesions after allogeneic bone marrow transplantation].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2015, Volume: 56, Issue:12

    Topics: Bone Marrow Transplantation; Cytarabine; Gastrointestinal Diseases; Graft vs Host Disease; Humans; Infliximab; Leukemia, Myeloid, Acute; Male; Middle Aged; Transplantation, Homologous

2015
Investigating the synergistic mechanism between ibrutinib and daunorubicin in acute myeloid leukemia cells.
    Leukemia & lymphoma, 2016, Volume: 57, Issue:10

    Topics: Adenine; Cytarabine; Daunorubicin; Leukemia, Myeloid, Acute; Piperidines; Pyrazoles; Pyrimidines

2016
Targeting CXCR4/SDF-1 axis by lipopolymer complexes of siRNA in acute myeloid leukemia.
    Journal of controlled release : official journal of the Controlled Release Society, 2016, Feb-28, Volume: 224

    Topics: Antimetabolites; Bone Marrow Cells; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Chemokine CXCL12; Cytarabine; Drug Delivery Systems; Gene Silencing; Humans; Leukemia, Myeloid, Acute; Lipids; Polymers; Receptors, CXCR4; RNA, Small Interfering; Stromal Cells

2016
Clofarabine Plus Low-Dose Cytarabine Is as Effective as and Less Toxic Than Intensive Chemotherapy in Elderly AML Patients.
    Clinical lymphoma, myeloma & leukemia, 2016, Volume: 16, Issue:3

    Topics: Adenine Nucleotides; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cohort Studies; Combined Modality Therapy; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Retreatment; Treatment Outcome

2016
Prediction of early death in adults with relapsed or refractory acute myeloid leukemia.
    Leukemia & lymphoma, 2016, Volume: 57, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cause of Death; Cohort Studies; Cytarabine; Drug Resistance, Neoplasm; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Recurrence; Time Factors; Treatment Failure; Young Adult

2016
[Outcomes of refractory or relapsed DNMT3A + cytogenetically normal acute myeloid leukemia patients followed the therapy including decitabine combined with CAG or CAG-like regimen].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2015, Volume: 36, Issue:12

    Topics: Aclarubicin; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Decitabine; Disease-Free Survival; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Mutation; Remission Induction; Retrospective Studies

2015
Prior hypomethylating agent use lacks impact on clinical outcome in patients with secondary acute myeloid leukemia arising from myelodysplastic syndromes treated with standard induction chemotherapy.
    International journal of hematology, 2016, Volume: 103, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anthracyclines; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Decitabine; Female; Hematopoietic Stem Cell Transplantation; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Neoplasms, Second Primary; Survival Analysis; Treatment Outcome; Young Adult

2016
Midostaurin, bortezomib and MEC in relapsed/refractory acute myeloid leukemia.
    Leukemia & lymphoma, 2016, Volume: 57, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bortezomib; Chromosome Aberrations; Cytarabine; Drug Monitoring; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Maximum Tolerated Dose; Middle Aged; Mitoxantrone; Recurrence; Remission Induction; Retreatment; Staurosporine; Treatment Outcome; Young Adult

2016
A low-dose cytarabine, aclarubicin and granulocyte colony-stimulating factor priming regimen versus a daunorubicin plus cytarabine regimen as induction therapy for older patients with acute myeloid leukemia: A propensity score analysis.
    Leukemia research, 2016, Volume: 42

    Topics: Aclarubicin; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Granulocyte Colony-Stimulating Factor; Humans; Induction Chemotherapy; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Propensity Score; Proportional Hazards Models; Retrospective Studies

2016
Does High-Dose Cytarabine Cause More Fungal Infection in Patients With Acute Myeloid Leukemia Undergoing Consolidation Therapy: A Multicenter, Prospective, Observational Study in China.
    Medicine, 2016, Volume: 95, Issue:4

    Topics: Adolescent; Adult; Anthracyclines; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy-Induced Febrile Neutropenia; Child; Child, Preschool; China; Consolidation Chemotherapy; Cytarabine; Female; Humans; Incidence; Infant; Length of Stay; Leukemia, Myeloid, Acute; Male; Middle Aged; Mycoses; Prospective Studies; Survival Rate; Vidarabine; Young Adult

2016
Favorable clinical outcome and unique characteristics in association with Twist1 overexpression in de novo acute myeloid leukemia.
    Blood cancer journal, 2015, Aug-14, Volume: 5

    Topics: Antineoplastic Agents; Bone Marrow; Cell Line; Cytarabine; Epithelial-Mesenchymal Transition; Humans; Leukemia, Myeloid, Acute; Nuclear Proteins; Polycomb Repressive Complex 1; Prognosis; Twist-Related Protein 1

2015
ABCC4 Is a Determinant of Cytarabine-Induced Cytotoxicity and Myelosuppression.
    Clinical and translational science, 2016, Volume: 9, Issue:1

    Topics: Animals; Biological Transport; Cell Death; Cell Line, Tumor; Child, Preschool; Cytarabine; Gene Knockdown Techniques; Gene Silencing; Humans; Leukemia, Myeloid, Acute; Mice, Inbred C57BL; Multidrug Resistance-Associated Proteins; Myeloid Progenitor Cells

2016
Synergisitic and Antagonistic AML Cell Type-specific Responses to 5-Aza-2-deoxycitidine and 1-h-D-Arabinofuranoside.
    Anticancer research, 2016, Volume: 36, Issue:2

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cell Line, Tumor; Cell Survival; Cytarabine; Decitabine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; Humans; Leukemia, Myeloid, Acute; Time Factors

2016
Infections in patients with acute myeloid leukemia treated with low-intensity therapeutic regimens: Risk factors and efficacy of antibiotic prophylaxis.
    Leukemia research, 2016, Volume: 42

    Topics: Adult; Aged; Aged, 80 and over; Antibiotic Prophylaxis; Antimetabolites, Antineoplastic; Azacitidine; Bacterial Infections; Cytarabine; Decitabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Retrospective Studies; Risk Factors; Virus Diseases

2016
[Clinic Outcome of FLAG Regimen treating Patients with Refractory and Relapse Acute Myeloid Leukemia].
    Zhongguo shi yan xue ye xue za zhi, 2016, Volume: 24, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chronic Disease; Cytarabine; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Middle Aged; Recurrence; Remission Induction; Survival Rate; Treatment Outcome; Vidarabine; Young Adult

2016
Dose-reduced combination of mitoxantrone, etoposide, and cytarabine (miniMEC) for relapsed and refractory acute leukemia.
    Leukemia & lymphoma, 2016, Volume: 57, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Retreatment; Treatment Outcome; Young Adult

2016
Enhanced autophagy in cytarabine arabinoside-resistant U937 leukemia cells and its potential as a target for overcoming resistance.
    Molecular medicine reports, 2016, Volume: 13, Issue:4

    Topics: Antimetabolites, Antineoplastic; Autophagy; Blotting, Western; Cytarabine; Drug Resistance, Neoplasm; Genes, Reporter; Green Fluorescent Proteins; Humans; Hydroxychloroquine; Leukemia, Myeloid, Acute; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Microtubule-Associated Proteins; U937 Cells

2016
Homoharringtonine, aclarubicin and cytarabine (HAA) regimen as the first course of induction therapy is highly effective for acute myeloid leukemia with t (8;21).
    Leukemia research, 2016, Volume: 44

    Topics: Aclarubicin; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Core Binding Factor Alpha 2 Subunit; Cytarabine; Female; Follow-Up Studies; Harringtonines; Homoharringtonine; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Oncogene Proteins, Fusion; Prognosis; Real-Time Polymerase Chain Reaction; Remission Induction; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RUNX1 Translocation Partner 1 Protein; Survival Rate; Translocation, Genetic; Young Adult

2016
[Long-term outcomes of homoharringtonine, cytarabine, daunorubicin or idarubicin (HAD/HAI) as induction chemotherapy in de novo acute myeloid leukemia].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2016, Volume: 37, Issue:2

    Topics: Cytarabine; Daunorubicin; Harringtonines; Homoharringtonine; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Leukocyte Count; Prognosis; Prospective Studies; Remission Induction; Retrospective Studies; Survival Rate

2016
[Efficacy of HAA regimen in the treatment of 64 patients with refractory/relapsed acute myeloid leukemia].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2016, Volume: 37, Issue:2

    Topics: Aclarubicin; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Harringtonines; Homoharringtonine; Humans; Leukemia, Myeloid, Acute; Recurrence; Remission Induction; Retrospective Studies; Salvage Therapy; Survival Rate

2016
Wernicke's Encephalopathy in an Acute Myeloid Leukemia Patient: A Case Study.
    Turkish journal of haematology : official journal of Turkish Society of Haematology, 2016, Mar-05, Volume: 33, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Thiamine; Vidarabine; Wernicke Encephalopathy

2016
The fludarabine, cytarabine, and granulocyte colony-stimulating factor (FLAG) chemotherapy regimen is an alternative to anthracycline-based therapy for the treatment of acute myeloid leukemia for patients with pre-existing cardiac disease.
    European journal of haematology, 2016, Volume: 97, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Comorbidity; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Heart Diseases; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasms, Second Primary; Retrospective Studies; Treatment Outcome; Vidarabine; Young Adult

2016
[Comparison of efficacy and prognostic factors in elderly acute myelogenous patients with MA or CAG induction chemotherapy regimen].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2016, Volume: 37, Issue:3

    Topics: Aclarubicin; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Granulocyte Colony-Stimulating Factor; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Mutation; Nucleophosmin; Prognosis; Remission Induction; Retrospective Studies; Survival Rate

2016
Prediction of CR following a second course of '7+3' in patients with newly diagnosed acute myeloid leukemia not in CR after a first course.
    Leukemia, 2016, Volume: 30, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Guideline Adherence; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Practice Guidelines as Topic

2016
Valproic acid enhances the antileukemic effect of cytarabine by triggering cell apoptosis.
    International journal of molecular medicine, 2016, Volume: 37, Issue:6

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; bcl-2-Associated X Protein; Bone Marrow Cells; Cell Line; Cell Proliferation; Cytarabine; Disease Models, Animal; Drug Combinations; Drug Synergism; Enzyme Inhibitors; G1 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; K562 Cells; Leukemia, Myeloid, Acute; Mice; Monocytes; Primary Cell Culture; Signal Transduction; Survival Analysis; Valproic Acid

2016
High feasibility and antileukemic efficacy of fludarabine, cytarabine, and idarubicin (FLAI) induction followed by risk-oriented consolidation: A critical review of a 10-year, single-center experience in younger, non M3 AML patients.
    American journal of hematology, 2016, Volume: 91, Issue:8

    Topics: Adolescent; Adult; Aged; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Child; Consolidation Chemotherapy; Cytarabine; Female; Gemtuzumab; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Retrospective Studies; Survival Analysis; Survival Rate; Treatment Outcome; Vidarabine; Young Adult

2016
[Efficacy analysis of CAG priming regimen combined with talidomide, interferon and interleukin 2 as the induction therapy for relapsed refractory acute myeloid leukemia].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2016, Volume: 37, Issue:4

    Topics: Aclarubicin; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Interferons; Interleukin-2; Leukemia, Myeloid, Acute; Recurrence; Remission Induction; Thalidomide

2016
Binding of Released Bim to Mcl-1 is a Mechanism of Intrinsic Resistance to ABT-199 which can be Overcome by Combination with Daunorubicin or Cytarabine in AML Cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2016, Sep-01, Volume: 22, Issue:17

    Topics: Antineoplastic Agents; Apoptosis; Bcl-2-Like Protein 11; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Drug Synergism; Humans; Leukemia, Myeloid, Acute; Myeloid Cell Leukemia Sequence 1 Protein; Protein Stability; Sulfonamides

2016
A prognostic model for survival after salvage treatment with FLAG-Ida +/- gemtuzumab-ozogamicine in adult patients with refractory/relapsed acute myeloid leukaemia.
    British journal of haematology, 2016, Volume: 174, Issue:5

    Topics: Adolescent; Adult; Aged; Allografts; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Gemtuzumab; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Leukemia, Myeloid, Acute; Middle Aged; Prognosis; Remission Induction; Retrospective Studies; Risk Assessment; Salvage Therapy; Survival Analysis; Vidarabine; Young Adult

2016
Expression Levels of Human Equilibrative Nucleoside Transporter 1 and Deoxycytidine Kinase Enzyme as Prognostic Factors in Patients with Acute Myeloid Leukemia Treated with Cytarabine.
    Chemotherapy, 2016, Volume: 61, Issue:6

    Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Cytarabine; Deoxycytidine Kinase; Doxorubicin; Equilibrative Nucleoside Transporter 1; Female; Gene Expression Regulation, Leukemic; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Proportional Hazards Models; Real-Time Polymerase Chain Reaction; Survival Rate; Treatment Outcome; Young Adult

2016
Evaluation of artemisinins for the treatment of acute myeloid leukemia.
    Cancer chemotherapy and pharmacology, 2016, Volume: 77, Issue:6

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Artemisinins; Artesunate; Cell Line, Tumor; Cell Survival; Cytarabine; High-Throughput Screening Assays; Humans; Leukemia, Myeloid, Acute; Lysosomes; Mice, Inbred Strains; Reactive Oxygen Species; Xenograft Model Antitumor Assays

2016
Micafungin as primary antifungal prophylaxis in patients presenting with acute myeloid leukemia.
    Medecine et maladies infectieuses, 2016, Volume: 46, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Bacterial Infections; Cytarabine; Daunorubicin; Echinocandins; Febrile Neutropenia; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Lipopeptides; Male; Micafungin; Middle Aged; Mycoses; Prospective Studies; Young Adult

2016
The role of VDR and BIM in potentiation of cytarabine-induced cell death in human AML blasts.
    Oncotarget, 2016, Jun-14, Volume: 7, Issue:24

    Topics: Abietanes; Adult; Aged; Aged, 80 and over; Apoptosis; Bcl-2-Like Protein 11; Cytarabine; Drug Synergism; Ergocalciferols; Female; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Receptors, Calcitriol; RNA Interference; Tumor Cells, Cultured; U937 Cells

2016
[Effectiveness of CLAT Protocol for Treating Patients with Refractory Acute Myeloid Leukemia].
    Zhongguo shi yan xue ye xue za zhi, 2016, Volume: 24, Issue:2

    Topics: Adolescent; Adult; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Thrombocytopenia; Topotecan; Young Adult

2016
[Clinical Efficacy of Sorafenib Combined with Low Dose Cytarabine for Treating Patients with FLT3+ Relapsed and Refractory Acute Myeloid Leukemia].
    Zhongguo shi yan xue ye xue za zhi, 2016, Volume: 24, Issue:2

    Topics: Cytarabine; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Niacinamide; Phenylurea Compounds; Recurrence; Remission Induction; Sorafenib; Treatment Outcome

2016
CLAG-based induction therapy in previously untreated high risk acute myeloid leukemia patients.
    Leukemia research, 2016, Volume: 46

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Risk; Survival Rate; Treatment Outcome

2016
Addition of High-Dose Cytarabine to Fludarabine-Based Conditioning for Hematopoietic Stem Cell Transplantation for Treating Fanconi Anemia Patients with Advanced Myeloid Malignancy: A Single-Center Experience and Literature Review.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2016, Volume: 22, Issue:9

    Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Cytarabine; Fanconi Anemia; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Myeloablative Agonists; Transplantation Conditioning; Treatment Outcome; Unrelated Donors; Vidarabine

2016
Evolving Therapies in Acute Myeloid Leukemia: Progress at Last?
    American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting, 2016, Volume: 35

    Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Humans; Leukemia, Myeloid, Acute; Neoplasm, Residual; Remission Induction

2016
Cytosine arabinoside and daunorubicin induction therapy in a patient with acute myeloid leukemia on chronic hemodialysis.
    Anti-cancer drugs, 2016, Volume: 27, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Induction Chemotherapy; Kidney Failure, Chronic; Leukemia, Myeloid, Acute; Middle Aged; Renal Dialysis

2016
Granulocyte infusion: benefit beyond neutrophils?
    Transfusion medicine (Oxford, England), 2016, Volume: 26, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Granulocytes; Humans; Leukemia, Myeloid, Acute; Leukocyte Transfusion; Middle Aged; Pulmonary Aspergillosis

2016
AMD3100 and G-CSF disrupt the cross-talk between leukemia cells and the endosteal niche and enhance their sensitivity to chemotherapeutic drugs in biomimetic polystyrene scaffolds.
    Blood cells, molecules & diseases, 2016, Volume: 59

    Topics: Antineoplastic Agents; Apoptosis; Benzylamines; Biomimetic Materials; Cell Adhesion; Cell Movement; Cells, Cultured; Chemokine CXCL12; Cyclams; Cytarabine; Granulocyte Colony-Stimulating Factor; Heterocyclic Compounds; Humans; Leukemia; Leukemia, Myeloid, Acute; Polystyrenes; Receptor Cross-Talk; Receptors, CXCR4; Stromal Cells

2016
[Role of Rheb in Human Acute Myeloid Leukemia].
    Zhongguo shi yan xue ye xue za zhi, 2016, Volume: 24, Issue:3

    Topics: Adult; Apoptosis; Bone Marrow; Cytarabine; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Monomeric GTP-Binding Proteins; Neuropeptides; Ras Homolog Enriched in Brain Protein; Real-Time Polymerase Chain Reaction; RNA, Messenger; Spleen

2016
[Comparison of Curative Effects of HAG and CAG Regimens for Patients with AML and Medium/High-Risk MDS].
    Zhongguo shi yan xue ye xue za zhi, 2016, Volume: 24, Issue:3

    Topics: Aclarubicin; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Examination; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Remission Induction

2016
Pim kinase inhibition sensitizes FLT3-ITD acute myeloid leukemia cells to topoisomerase 2 inhibitors through increased DNA damage and oxidative stress.
    Oncotarget, 2016, Jul-26, Volume: 7, Issue:30

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biphenyl Compounds; Cytarabine; DNA Damage; Drug Synergism; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Oxidative Stress; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-pim-1; Reactive Oxygen Species; Signal Transduction; Thiazolidines; Topoisomerase II Inhibitors

2016
Correlation of NPM1 Type A Mutation Burden With Clinical Status and Outcomes in Acute Myeloid Leukemia Patients With Mutated NPM1 Type A.
    Annals of laboratory medicine, 2016, Volume: 36, Issue:5

    Topics: Antineoplastic Agents; Bone Marrow; Cytarabine; Daunorubicin; fms-Like Tyrosine Kinase 3; Humans; Karyotype; Leukemia, Myeloid, Acute; Mutation; Nuclear Proteins; Nucleophosmin; Real-Time Polymerase Chain Reaction; Recurrence; Remission Induction; Retrospective Studies; Sequence Analysis, DNA

2016
Smac mimetic induces cell death in a large proportion of primary acute myeloid leukemia samples, which correlates with defined molecular markers.
    Oncotarget, 2016, Aug-02, Volume: 7, Issue:31

    Topics: Adult; Aged; Aged, 80 and over; Apoptosis; Apoptosis Regulatory Proteins; Cell Death; Cell Line, Tumor; Cell Survival; Cytarabine; Female; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Humans; Intracellular Signaling Peptides and Proteins; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitochondrial Proteins; Mutation; NF-kappa B; Nucleophosmin; Receptors, Tumor Necrosis Factor, Type I; Signal Transduction; Treatment Outcome; Young Adult

2016
Successful Cytoreduction with CAG (cytarabine, Aclarubicin and G-CSF) Therapy in Refractory Acute Myelogenous Leukemia before Allogeneic Stem Cell Transplantation.
    Hematology (Amsterdam, Netherlands), 2001, Volume: 6, Issue:6

    Topics: Aclarubicin; Adolescent; Adult; Allografts; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Peripheral Blood Stem Cell Transplantation; Remission Induction

2001
[A Case of a Multidisciplinary Team Approach to Serious Hand-Foot Syndrome Induced by High-Dose Cytarabine Therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2016, Volume: 43, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Erythema; Female; Hand-Foot Syndrome; Humans; Idarubicin; Leukemia, Myeloid, Acute; Patient Care Team; Treatment Outcome

2016
Small-molecule Hedgehog inhibitor attenuates the leukemia-initiation potential of acute myeloid leukemia cells.
    Cancer science, 2016, Volume: 107, Issue:10

    Topics: Animals; Antimetabolites, Antineoplastic; Cell Cycle; Cell Line, Tumor; Cell Self Renewal; Cell Transformation, Neoplastic; Cytarabine; Disease Models, Animal; Drug Resistance, Neoplasm; Gene Expression Profiling; Hedgehog Proteins; Humans; Leukemia, Myeloid, Acute; Mice; Neoplastic Stem Cells; Signal Transduction; Xenograft Model Antitumor Assays

2016
Inhibition of Mnk enhances apoptotic activity of cytarabine in acute myeloid leukemia cells.
    Oncotarget, 2016, Aug-30, Volume: 7, Issue:35

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Caspase 3; Caspase 7; Cell Line, Tumor; Cell Proliferation; Cell Survival; Copper-Transporting ATPases; Cytarabine; Drug Resistance, Neoplasm; Enzyme Activation; Gene Expression Regulation, Leukemic; Humans; Leukemia, Myeloid, Acute; MAP Kinase Signaling System; Phosphorylation; RNA, Small Interfering; Signal Transduction

2016
The outcome and prognostic factors of 248 elderly patients with acute myeloid leukemia treated with standard-dose or low-intensity induction therapy.
    Medicine, 2016, Volume: 95, Issue:30

    Topics: Aclarubicin; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Induction Chemotherapy; L-Lactate Dehydrogenase; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Prognosis; Retrospective Studies

2016
Cytoprotective autophagy maintains leukemia-initiating cells in murine myeloid leukemia.
    Blood, 2016, 09-22, Volume: 128, Issue:12

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Autophagy; Autophagy-Related Protein 5; Autophagy-Related Protein 7; Cytarabine; Leukemia, Experimental; Leukemia, Myeloid, Acute; Mice; Mice, Inbred C57BL; Mice, Knockout; Neoplastic Stem Cells; Signal Transduction

2016
Effect of granulocyte colony-stimulating factor priming combined with low-dose cytarabine and homoharringtonine in higher risk myelodysplastic syndrome patients.
    Leukemia research, 2016, Volume: 48

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Harringtonines; Homoharringtonine; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Neutropenia; Pilot Projects; Remission Induction; Risk; Young Adult

2016
Severe palmar-plantar erythrodysesthesia and aplasia in an adult undergoing re-induction treatment with high-dose cytarabine for acute myelogenous leukemia: a possible drug interaction between posaconazole and cytarabine.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2017, Volume: 23, Issue:6

    Topics: Cytarabine; Drug Interactions; Erythema; Female; Hand-Foot Syndrome; Humans; Leukemia, Myeloid, Acute; Triazoles; Young Adult

2017
[Efficacy and safety analysis of the combination of cladribine, cytarabine, granulocyte colonystimulating factor (CLAG) regime in patients with refractory or relapsed acute myeloid leukemia].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2016, Volume: 37, Issue:7

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neutropenia; Recurrence; Retrospective Studies; Young Adult

2016
Comparison of cladribine- and fludarabine-based induction chemotherapy in relapsed or refractory acute myeloid leukaemia.
    Annals of hematology, 2016, Volume: 95, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Allografts; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Drug Evaluation; Drug Resistance, Neoplasm; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Proportional Hazards Models; Recurrence; Retrospective Studies; Salvage Therapy; Treatment Outcome; Vidarabine

2016
[High-intensity chemotherapy versus palliative chemotherapy in patients over 60 years with acute myeloid leukemia].
    Revista medica del Instituto Mexicano del Seguro Social, 2016, Volume: 54 Suppl 2

    Topics: Aged; Aged, 80 and over; Anthracyclines; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Palliative Care; Retrospective Studies; Treatment Outcome

2016
Combination screening in vitro identifies synergistically acting KP372-1 and cytarabine against acute myeloid leukemia.
    Biochemical pharmacology, 2016, Oct-15, Volume: 118

    Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Survival; Cytarabine; Drug Screening Assays, Antitumor; Drug Synergism; Female; Fluorescein; Fluorescent Dyes; Heterocyclic Compounds, 4 or More Rings; High-Throughput Screening Assays; Humans; Inhibitory Concentration 50; Leukemia, Myeloid, Acute; Male; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Small Molecule Libraries; Spectrometry, Fluorescence; Tetrazoles; Tumor Cells, Cultured

2016
A comparison of clofarabine with ara-C, each in combination with daunorubicin as induction treatment in older patients with acute myeloid leukaemia.
    Leukemia, 2017, Volume: 31, Issue:2

    Topics: Adenine Nucleotides; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Cause of Death; Clofarabine; Cytarabine; Daunorubicin; Female; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Survival Analysis; Treatment Outcome

2017
BRAF signals to pro-apoptotic BIM to enhance AraC cytotoxicity induced in AML cells by Vitamin D-based differentiation agents.
    The Journal of steroid biochemistry and molecular biology, 2017, Volume: 173

    Topics: Antineoplastic Agents; Apoptosis; Bcl-2-Like Protein 11; Cell Differentiation; Cell Line, Tumor; Cells, Cultured; Cytarabine; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Proto-Oncogene Proteins B-raf; Signal Transduction; Vitamin D

2017
Comparison of Clinical Efficacy of Cytarabine with Different Regimens in Postremission Consolidation Therapy for Adult t(8;21) AML Patients: A Multicenter Retrospective Study in China.
    Acta haematologica, 2016, Volume: 136, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; China; Cytarabine; Humans; Leukemia, Myeloid, Acute; Remission Induction; Retrospective Studies; Treatment Outcome

2016
Persistence of minimal residual disease assessed by multiparameter flow cytometry is highly prognostic in younger patients with acute myeloid leukemia.
    Cancer, 2017, 02-01, Volume: 123, Issue:3

    Topics: Adult; Aged; Cytarabine; Disease-Free Survival; Female; Flow Cytometry; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm, Residual; Prognosis; Remission Induction

2017
AC220 and AraC cause differential inhibitory dynamics in patient-derived M5-AML with FLT3-ITD and, thus, ultimately distinct therapeutic outcomes.
    Experimental hematology, 2017, Volume: 45

    Topics: Aged; Animals; Antimetabolites, Antineoplastic; Benzothiazoles; Cytarabine; Disease Models, Animal; DNA Mutational Analysis; fms-Like Tyrosine Kinase 3; Gene Duplication; Genotype; Humans; Immunophenotyping; Leukemia, Myeloid, Acute; Male; Mice; Mice, Inbred NOD; Mice, SCID; Phenotype; Phenylurea Compounds; Protein Kinase Inhibitors; Tandem Repeat Sequences; Treatment Outcome; Tumor Burden; Xenograft Model Antitumor Assays

2017
Comparison of Reduced-Intensity Idarubicin and Daunorubicin Plus Cytarabine as Induction Chemotherapy for Elderly Patients with Newly Diagnosed Acute Myeloid Leukemia.
    Clinical drug investigation, 2017, Volume: 37, Issue:2

    Topics: Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Idarubicin; Induction Chemotherapy; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Patient Safety; Retrospective Studies; Survival Analysis; Treatment Outcome

2017
Cladribine, cytarabine and idarubicin (CLA-Ida) salvage chemotherapy in relapsed acute myeloid leukemia (AML).
    Leukemia & lymphoma, 2017, Volume: 58, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cytarabine; Female; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Remission Induction; Salvage Therapy; Transplantation, Homologous; Treatment Outcome; Young Adult

2017
Enhanced Fructose Utilization Mediated by SLC2A5 Is a Unique Metabolic Feature of Acute Myeloid Leukemia with Therapeutic Potential.
    Cancer cell, 2016, Nov-14, Volume: 30, Issue:5

    Topics: Animals; Cell Line, Tumor; Cytarabine; Drug Synergism; Fructose; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glucose Transporter Type 5; Humans; Leukemia, Myeloid, Acute; Mannitol; Mice; Prognosis; Treatment Outcome; Up-Regulation

2016
Targeting autophagy to overcome chemoresistance in acute myleogenous leukemia.
    Autophagy, 2017, Jan-02, Volume: 13, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Autophagy; Cell Line, Tumor; Coculture Techniques; Cytarabine; Drug Resistance, Neoplasm; Gene Silencing; Humans; Idarubicin; Leukemia, Myeloid, Acute; Mesenchymal Stem Cells; Mice; Mice, SCID; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Tumor Microenvironment

2017
Acute myeloid leukemia therapy elicits durable complete response in chemoradio-resistant metastatic paraganglioma.
    Pediatric blood & cancer, 2017, Volume: 64, Issue:5

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Cytarabine; Dacarbazine; Daunorubicin; Drug Resistance, Neoplasm; Etoposide; Humans; Iodobenzenes; Leukemia, Myeloid, Acute; Male; Paraganglioma; Radiation Tolerance; Temozolomide

2017
Fludarabine and Cytarabine Combination in the Induction of Adult Patients with Acute Myeloid Leukaemia.
    Acta haematologica, 2017, Volume: 137, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Drug Administration Schedule; Female; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Retrospective Studies; Survival Analysis; Vidarabine

2017
Using genome-wide CRISPR library screening with library resistant DCK to find new sources of Ara-C drug resistance in AML.
    Scientific reports, 2016, 11-03, Volume: 6

    Topics: Animals; Base Sequence; Cell Line; Clone Cells; Clustered Regularly Interspaced Short Palindromic Repeats; Cytarabine; Deoxycytidine Kinase; Dexamethasone; DNA, Complementary; Drug Resistance, Neoplasm; Equilibrative Nucleoside Transporter 1; Gene Library; Genetic Loci; Genetic Testing; Genome, Human; Glucocorticoids; Humans; Inhibitory Concentration 50; Leukemia, Myeloid, Acute; Mice; Mutation; Prednisolone; Receptors, Glucocorticoid; Reproducibility of Results; RNA, Guide, Kinetoplastida; U937 Cells

2016
Sequential Intensified Conditioning Regimen Allogeneic Hematopoietic Stem Cell Transplantation in Adult Patients with Intermediate- or High-Risk Acute Myeloid Leukemia in Complete Remission: A Study from the Acute Leukemia Working Party of the European Gr
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2017, Volume: 23, Issue:2

    Topics: Adolescent; Adult; Aged; Allografts; Amsacrine; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Cytarabine; Disease-Free Survival; Female; Graft vs Host Disease; Histocompatibility; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Peripheral Blood Stem Cell Transplantation; Proportional Hazards Models; Remission Induction; Retrospective Studies; Risk; Transplantation Conditioning; Vidarabine; Whole-Body Irradiation; Young Adult

2017
Enhanced sensitivity to glucocorticoids in cytarabine-resistant AML.
    Leukemia, 2017, Volume: 31, Issue:5

    Topics: Adult; Cytarabine; Drug Resistance, Neoplasm; fms-Like Tyrosine Kinase 3; Gene Expression Profiling; Glucocorticoids; Humans; Leukemia, Myeloid, Acute; Tumor Cells, Cultured; Young Adult

2017
Association between the TP53 Arg72Pro polymorphism and clinical outcomes in acute myeloid leukemia.
    Haematologica, 2017, Volume: 102, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Alleles; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cytarabine; Daunorubicin; Etoposide; Female; Gene Expression; Genetic Predisposition to Disease; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Polymorphism, Single Nucleotide; Prognosis; Retrospective Studies; Survival Analysis; Thioguanine; Tumor Suppressor Protein p53

2017
NT1721, a novel epidithiodiketopiperazine, exhibits potent in vitro and in vivo efficacy against acute myeloid leukemia.
    Oncotarget, 2016, Dec-27, Volume: 7, Issue:52

    Topics: Animals; Cell Line, Tumor; Cytarabine; DNA (Cytosine-5-)-Methyltransferase 1; Humans; Leukemia, Myeloid, Acute; Membrane Proteins; Mice; Niacinamide; Phenylurea Compounds; Piperazines; Polycomb Repressive Complex 1; Sorafenib

2016
NUP98-fusion transcripts characterize different biological entities within acute myeloid leukemia: a report from the AIEOP-AML group.
    Leukemia, 2017, Volume: 31, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Biomarkers, Tumor; Cyclophosphamide; Cytarabine; Daunorubicin; Down-Regulation; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Mutation; Nuclear Pore Complex Proteins; Oncogene Proteins, Fusion; Prednisone; Prognosis; Translocation, Genetic; Up-Regulation; Vincristine

2017
Association of a cytarabine chemosensitivity related gene expression signature with survival in cytogenetically normal acute myeloid leukemia.
    Oncotarget, 2017, Jan-03, Volume: 8, Issue:1

    Topics: Antimetabolites, Antineoplastic; Cytarabine; Drug Resistance, Neoplasm; Gene Expression Profiling; Humans; Leukemia, Myeloid, Acute; Prognosis; Survival Analysis

2017
Optimal AraC-Cytotoxicity to AML Cells Requires ERK5 Activity.
    Journal of cellular biochemistry, 2017, Volume: 118, Issue:6

    Topics: Aniline Compounds; Antimetabolites, Antineoplastic; Benzodiazepinones; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Cytarabine; Gene Expression Regulation, Leukemic; HL-60 Cells; Humans; Indoles; Leukemia, Myeloid, Acute; Mitogen-Activated Protein Kinase 7; Phosphorylation; Proto-Oncogene Proteins c-bcl-2

2017
Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia.
    Nature medicine, 2017, Volume: 23, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Agents; Blotting, Western; Bortezomib; CDC2 Protein Kinase; Cell Line, Tumor; Cyclin-Dependent Kinases; Cytarabine; Drug Resistance, Neoplasm; Enhancer of Zeste Homolog 2 Protein; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Histones; Homeodomain Proteins; HSP90 Heat-Shock Proteins; Humans; Immunohistochemistry; Immunoprecipitation; Indoles; Leukemia, Myeloid, Acute; Male; Mass Spectrometry; Mice; Middle Aged; Neoplasm Transplantation; Proteasome Endopeptidase Complex; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Proteomics; Pyridones; Young Adult

2017
In vitro and in vivo anti-leukemic activity of the peptidase-potentiated alkylator melflufen in acute myeloid leukemia.
    Oncotarget, 2017, Jan-24, Volume: 8, Issue:4

    Topics: Animals; Antigens, CD34; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Synergism; Female; HL-60 Cells; Humans; Inhibitory Concentration 50; Leukemia, Myeloid, Acute; Male; Melphalan; Mice, SCID; Middle Aged; Neoplastic Stem Cells; Phenylalanine; Time Factors; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2017
Tunneling nanotube (TNT) formation is downregulated by cytarabine and NF-κB inhibition in acute myeloid leukemia (AML).
    Oncotarget, 2017, Jan-31, Volume: 8, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biological Transport; Cell Communication; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Female; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Lysosomes; Male; Microscopy, Fluorescence; Middle Aged; Nanotubes; NF-kappa B; Signal Transduction; THP-1 Cells; Tumor Cells, Cultured

2017
SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia.
    Nature medicine, 2017, Volume: 23, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cytarabine; Daunorubicin; Disease Models, Animal; Female; Flow Cytometry; Humans; Immunoblotting; Leukemia, Myeloid, Acute; Male; Middle Aged; Monomeric GTP-Binding Proteins; Prognosis; Retrospective Studies; SAM Domain and HD Domain-Containing Protein 1; Young Adult

2017
Fractionated gemtuzumab ozogamicin combined with intermediate-dose cytarabine and daunorubicin as salvage therapy in very high-risk AML patients: a bridge to reduced intensity conditioning transplant?
    Annals of hematology, 2017, Volume: 96, Issue:3

    Topics: Adult; Aged; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Cytarabine; Daunorubicin; Female; Gemtuzumab; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Retrospective Studies; Risk Factors; Salvage Therapy; Transplantation Conditioning; Treatment Outcome; Young Adult

2017
[Analysis of Therapy and Efficacy after Remission of Acute Myeloid Leukemia].
    Zhongguo shi yan xue ye xue za zhi, 2016, Volume: 24, Issue:6

    Topics: Cytarabine; Disease-Free Survival; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Remission Induction; Retrospective Studies; Risk Factors; Survival Rate; Transplantation Conditioning; Transplantation, Homologous

2016
Histone deacetylases 1 and 2 cooperate in regulating BRCA1, CHK1, and RAD51 expression in acute myeloid leukemia cells.
    Oncotarget, 2017, Jan-24, Volume: 8, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; BRCA1 Protein; Cell Cycle; Checkpoint Kinase 1; Cytarabine; Daunorubicin; DNA Damage; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Leukemic; Histone Deacetylase 1; Histone Deacetylase 2; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Indoles; Leukemia, Myeloid, Acute; Panobinostat; Rad51 Recombinase; RNA Interference; Signal Transduction; THP-1 Cells; Transfection

2017
Impact of FLT3-ITD diversity on response to induction chemotherapy in patients with acute myeloid leukemia.
    Haematologica, 2017, Volume: 102, Issue:4

    Topics: Amino Acid Motifs; Base Sequence; Cytarabine; fms-Like Tyrosine Kinase 3; Gene Expression; Genetic Variation; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Mitoxantrone; Protein Domains; Retrospective Studies; Sequence Analysis, DNA; Survival Analysis; Tandem Repeat Sequences

2017
Targeting SAMHD1 with the Vpx protein to improve cytarabine therapy for hematological malignancies.
    Nature medicine, 2017, Volume: 23, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Arabinofuranosylcytosine Triphosphate; Child; Child, Preschool; Cytarabine; Disease Models, Animal; Female; Humans; In Vitro Techniques; Infant; Leukemia, Myeloid, Acute; Male; Mice; Molecular Targeted Therapy; Monomeric GTP-Binding Proteins; Prognosis; SAM Domain and HD Domain-Containing Protein 1; Viral Regulatory and Accessory Proteins

2017
De novo AML exhibits greater microenvironment dysregulation compared to AML with myelodysplasia-related changes.
    Scientific reports, 2017, 01-13, Volume: 7

    Topics: Antimetabolites, Antineoplastic; Bone Marrow; Bone Marrow Cells; Case-Control Studies; Cell Line; Cell Proliferation; Cellular Microenvironment; Chemotaxis; Cytarabine; Cytokines; Female; Gene Expression Regulation; Gene Silencing; Humans; Immunomodulation; Leukemia, Myeloid, Acute; Male; MicroRNAs; Mitogen-Activated Protein Kinases; Myelodysplastic Syndromes; NF-kappa B; RNA Interference; Signal Transduction; T-Lymphocyte Subsets; Tumor Microenvironment

2017
Intesive fludarabine-high dose cytarabine-idarubicin combination as induction therapy with risk-adapted consolidation may improve treatment efficacy in younger Acute Myeloid Leukemia (AML) patients: Rationales, evidences and future perspectives.
    Bioscience trends, 2017, Mar-22, Volume: 11, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Consolidation Chemotherapy; Cytarabine; Dose-Response Relationship, Drug; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Stem Cell Transplantation; Treatment Outcome; Vidarabine; Young Adult

2017
Antibody-Targeted Cyclodextrin-Based Nanoparticles for siRNA Delivery in the Treatment of Acute Myeloid Leukemia: Physicochemical Characteristics, in Vitro Mechanistic Studies, and ex Vivo Patient Derived Therapeutic Efficacy.
    Molecular pharmaceutics, 2017, 03-06, Volume: 14, Issue:3

    Topics: Antibodies; Apoptosis; Cell Differentiation; Cell Line, Tumor; Cyclodextrins; Cytarabine; Down-Regulation; Humans; K562 Cells; Leukemia, Myeloid, Acute; Nanoparticles; Neoplastic Stem Cells; Receptors, Interleukin-3; RNA, Small Interfering; Transcription Factors

2017
Monkey business: Repurposing a protein from the simian immunodeficiency virus to enhance cytotoxic chemotherapy.
    Science translational medicine, 2017, 02-01, Volume: 9, Issue:375

    Topics: Animals; Cytarabine; Hematologic Neoplasms; Leukemia, Myeloid, Acute; SAM Domain and HD Domain-Containing Protein 1; Simian Immunodeficiency Virus

2017
Resistance of leukemia cells to cytarabine chemotherapy is mediated by bone marrow stroma, involves cell-surface equilibrative nucleoside transporter-1 removal and correlates with patient outcome.
    Oncotarget, 2017, Apr-04, Volume: 8, Issue:14

    Topics: Bone Marrow; Bone Marrow Cells; Cell Line, Tumor; Cytarabine; Drug Resistance, Neoplasm; Equilibrative Nucleoside Transporter 1; Humans; Leukemia, Myeloid, Acute; Patient Outcome Assessment; Stromal Cells

2017
Mechanisms responsible for the synergistic antileukemic interactions between ATR inhibition and cytarabine in acute myeloid leukemia cells.
    Scientific reports, 2017, 02-08, Volume: 7

    Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Checkpoints; Cell Proliferation; Child; Cytarabine; Drug Combinations; Drug Interactions; Drug Synergism; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Morpholines; Prognosis; Pyrimidines; Tumor Cells, Cultured; Young Adult

2017
Decitabine before Low-Dose Cytarabine-Based Chemotherapy Combined with Human Leukocyte Antigen-Mismatched Stem Cell Microtransplantation Improved Outcomes in Elderly Patients with Newly Diagnosed Acute Myeloid Leukemia.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2017, Volume: 23, Issue:5

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Decitabine; Histocompatibility; HLA Antigens; Humans; Karyotype; Leukemia, Myeloid, Acute; Middle Aged; Prospective Studies; Remission Induction; Stem Cell Transplantation

2017
Inhibition of serotonin receptor type 1 in acute myeloid leukemia impairs leukemia stem cell functionality: a promising novel therapeutic target.
    Leukemia, 2017, Volume: 31, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Animals; Cytarabine; Drug Resistance, Neoplasm; Female; Humans; Leukemia, Myeloid, Acute; Male; Mice; Middle Aged; Neoplastic Stem Cells; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Young Adult

2017
OCTN1 Is a High-Affinity Carrier of Nucleoside Analogues.
    Cancer research, 2017, 04-15, Volume: 77, Issue:8

    Topics: Animals; Antimetabolites, Antineoplastic; Child; CHO Cells; Cohort Studies; Cricetulus; Cytarabine; Deoxycytidine; Dipyridamole; Drug Resistance, Neoplasm; Gemcitabine; Gene Expression Profiling; HEK293 Cells; HeLa Cells; Humans; Leukemia, Myeloid, Acute; Organic Cation Transport Proteins; Symporters

2017
Effect of granulocyte colony-stimulating factor on outcomes in patients with non-M3 acute myelogenous leukemia treated with anthracycline-based induction (7+3 regimen) chemotherapies.
    Leukemia research, 2017, Volume: 57

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy-Induced Febrile Neutropenia; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Mortality; Remission Induction; Republic of Korea; Retrospective Studies; Treatment Outcome; Young Adult

2017
Outcome of relapsed core binding factor acute myeloid leukemia in children: A result from the Japanese Pediatric Leukemia/Lymphoma Study Group (JPLSG) AML-05R study.
    Pediatric blood & cancer, 2017, Volume: 64, Issue:10

    Topics: Adolescent; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Core Binding Factors; Cytarabine; Etoposide; Granulocyte Colony-Stimulating Factor; Humans; Induction Chemotherapy; Japan; Leukemia, Myeloid, Acute; Mitoxantrone; Proto-Oncogene Proteins c-kit; Recurrence; Retrospective Studies; Surveys and Questionnaires; Treatment Outcome; Vidarabine

2017
Clofarabine-based consolidation therapy in AML.
    The Lancet. Oncology, 2017, Volume: 18, Issue:4

    Topics: Adenine Nucleotides; Adolescent; Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Consolidation Chemotherapy; Cytarabine; Disease Progression; Disease-Free Survival; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Randomized Controlled Trials as Topic; Time Factors; Treatment Outcome; Young Adult

2017
Optimizing Therapeutic Effect of Aurora B Inhibition in Acute Myeloid Leukemia with AZD2811 Nanoparticles.
    Molecular cancer therapeutics, 2017, Volume: 16, Issue:6

    Topics: Animals; Antineoplastic Agents; Apoptosis; Aurora Kinase B; Bone Marrow; Cell Line, Tumor; Cytarabine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Mice; Nanoparticles; Organophosphates; Polyploidy; Protein Kinase Inhibitors; Quinazolines; Rats; Tumor Burden; Xenograft Model Antitumor Assays

2017
Assessment of Drug Sensitivity in Hematopoietic Stem and Progenitor Cells from Acute Myelogenous Leukemia and Myelodysplastic Syndrome Ex Vivo.
    Stem cells translational medicine, 2017, Volume: 6, Issue:3

    Topics: Cell Count; Cell Death; Cell Survival; Cyclopentanes; Cytarabine; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Pyrimidines

2017
Resistance to FLT3 inhibition in an in vitro model of primary AML cells with a stem cell phenotype in a defined microenvironment.
    Leukemia, 2008, Volume: 22, Issue:7

    Topics: ADP-ribosyl Cyclase 1; Antigens, CD34; Cell Line, Tumor; Cell Survival; Cytarabine; Drug Resistance, Neoplasm; fms-Like Tyrosine Kinase 3; Humans; Interleukin-3 Receptor alpha Subunit; Leukemia, Myeloid, Acute; Membrane Glycoproteins; Neoplastic Stem Cells; Phenotype; Receptors, Interleukin-3; Tyrphostins

2008
[HAA regimen as induction chemotherapy for newly diagnosed acute myelogenous leukemia].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2008, Volume: 29, Issue:1

    Topics: Aclarubicin; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Harringtonines; Homoharringtonine; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Retrospective Studies; Treatment Outcome; Young Adult

2008
Kinetics of bone marrow blasts during induction and achievement of complete remission in acute myeloid leukemia.
    Haematologica, 2008, Volume: 93, Issue:8

    Topics: Adult; Bone Marrow; Cytarabine; Humans; Kinetics; Leukemia, Myeloid, Acute; Probability; Remission Induction

2008
Spurious elevation of the cerebrospinous fluid white cell counts in three patients receiving liposomal cytarabine as part of post-remission therapy.
    Leukemia, 2008, Volume: 22, Issue:12

    Topics: Adult; Antimetabolites, Antineoplastic; Burkitt Lymphoma; Cerebrospinal Fluid; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Leukocyte Count; Liposomes; Male; Middle Aged; Remission Induction; Reproducibility of Results

2008
Induction therapy for elderly patients with acute myeloid leukemia.
    Blood reviews, 2008, Volume: 22, Issue:6

    Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Cytarabine; Female; Health Services for the Aged; Humans; Leukemia, Myeloid, Acute; Male

2008
Clinical significance of minimal residual disease in patients with t(8;21) acute myeloid leukemia in Japan.
    International journal of hematology, 2008, Volume: 88, Issue:2

    Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Core Binding Factor Alpha 2 Subunit; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Gene Dosage; Humans; Idarubicin; Japan; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm, Residual; Prognosis; Proto-Oncogene Proteins; Recurrence; Remission Induction; Retrospective Studies; RUNX1 Translocation Partner 1 Protein; Transcription Factors

2008
The kinase inhibitor LS104 induces apoptosis, enhances cytotoxic effects of chemotherapeutic drugs and is targeting the receptor tyrosine kinase FLT3 in acute myeloid leukemia.
    Leukemia research, 2008, Volume: 32, Issue:11

    Topics: Acrylonitrile; Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Bone Marrow; Cell Differentiation; Cell Proliferation; Colony-Forming Units Assay; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Fluorescent Antibody Technique; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Male; Mice; Middle Aged; Point Mutation; Signal Transduction; Styrenes; Tissue Distribution; Tumor Cells, Cultured

2008
Wilms' tumor 1 gene mutations independently predict poor outcome in adults with cytogenetically normal acute myeloid leukemia: a cancer and leukemia group B study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Oct-01, Volume: 26, Issue:28

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Busulfan; Cytarabine; Daunorubicin; Etoposide; Female; fms-Like Tyrosine Kinase 3; Genes, Wilms Tumor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Nucleophosmin; Prognosis; Proportional Hazards Models; Statistics, Nonparametric

2008
Localized small-bowel infarction caused by Aspergillus during chemotherapy for acute myeloid leukemia: report of a case.
    Surgery today, 2008, Volume: 38, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Aspergillosis; Cytarabine; Humans; Ileal Diseases; Immunocompromised Host; Intestinal Perforation; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone

2008
Neuroophthalmological side effects following intrathecal administration of liposomal cytarabine for central nervous system prophylaxis in three adolescents with acute myeloid leukaemia.
    Annals of hematology, 2008, Volume: 87, Issue:11

    Topics: Adolescent; Adrenal Cortex Hormones; Antimetabolites, Antineoplastic; Cytarabine; Dexamethasone; Female; Humans; Injections, Spinal; Leukemia, Myeloid, Acute; Liposomes; Male; Papilledema; Remission Induction

2008
Relapse of acute myeloid leukemia as isolated bilateral testicular granulocytic sarcoma in an adult.
    Urology journal, 2008,Spring, Volume: 5, Issue:2

    Topics: Antimetabolites, Antineoplastic; Cytarabine; Daunorubicin; Humans; Immunohistochemistry; Leukemia, Myeloid, Acute; Male; Middle Aged; Orchiectomy; Recurrence; Remission Induction; Sarcoma, Myeloid; Testicular Neoplasms

2008
Mucoepidermoid carcinoma of the submandibular gland after chemotherapy in a child.
    Auris, nasus, larynx, 2009, Volume: 36, Issue:2

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Busulfan; Carcinoma, Mucoepidermoid; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Disease-Free Survival; Etoposide; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Humans; Image Processing, Computer-Assisted; Leukemia, Myeloid, Acute; Male; Neck Dissection; Neoplasms, Second Primary; Positron-Emission Tomography; Submandibular Gland Neoplasms; Thioguanine; Tomography, X-Ray Computed; Transplantation Conditioning

2009
Toward optimization of postremission therapy for residual disease-positive patients with acute myeloid leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Oct-20, Volume: 26, Issue:30

    Topics: Adult; Aged; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm, Residual; Prognosis; Remission Induction; Stem Cell Transplantation; Transplantation, Autologous; Transplantation, Homologous; Treatment Outcome

2008
Neutrophilic dermatoses with acute myeloid leukemia associated with an increase of serum colony-stimulating factor.
    Journal of the American Academy of Dermatology, 2008, Volume: 59, Issue:2 Suppl 1

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Cytarabine; Folliculitis; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Sweet Syndrome

2008
[The efficacy of high-dose cytarabine for patients with t(8;21) AML and with normal karyotype AML].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2008, Volume: 29, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Cytarabine; Female; Humans; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Treatment Outcome; Young Adult

2008
Ligand-induced Flt3-downregulation modulates cell death associated proteins and enhances chemosensitivity to idarubicin in THP-1 acute myeloid leukemia cells.
    Leukemia research, 2009, Volume: 33, Issue:2

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; Cytarabine; Down-Regulation; Drug Synergism; fms-Like Tyrosine Kinase 3; Gene Expression Regulation, Neoplastic; Humans; Idarubicin; Leukemia, Myeloid, Acute; Ligands; Signal Transduction; Up-Regulation

2009
Neurological complications after intrathecal liposomal cytarabine application in patients after allogeneic haematopoietic stem cell transplantation.
    Annals of hematology, 2008, Volume: 87, Issue:12

    Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Cohort Studies; Cytarabine; Female; Hematopoietic Stem Cell Transplantation; Humans; Injections, Spinal; Leukemia, Myeloid, Acute; Liposomes; Lymphoma; Male; Meningitis; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Transplantation, Homologous

2008
Efficacy of fractionated gemtuzumab ozogamicin combined with cytarabine in advanced childhood myeloid leukaemia.
    British journal of haematology, 2008, Volume: 143, Issue:4

    Topics: Adolescent; Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Drug Administration Schedule; Drug Evaluation; Epidemiologic Methods; Female; Gemtuzumab; Humans; Infant; Leukemia, Myeloid, Acute; Male; Recurrence; Treatment Outcome

2008
Differential allelic expression in leukoblast from patients with acute myeloid leukemia suggests genetic regulation of CDA, DCK, NT5C2, NT5C3, and TP53.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:12

    Topics: 5'-Nucleotidase; Alleles; Cytarabine; Cytidine Deaminase; Deoxycytidine Kinase; Equilibrative Nucleoside Transporter 1; Gene Expression; Gene Expression Regulation, Neoplastic; Glycoproteins; Heterozygote; Homozygote; Humans; Leukemia, Myeloid, Acute; Polymorphism, Single Nucleotide; Tumor Suppressor Protein p53

2008
[Loeys-Dietz syndrome with acute myeloid leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2008, Volume: 49, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Marfan Syndrome; Middle Aged; Mutation, Missense; Receptors, Transforming Growth Factor beta; Remission Induction; Translocation, Genetic

2008
The management of prolonged, isolated hyperbilirubinemia following cytarabine-based chemotherapy for acute myeloid leukaemia.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2009, Volume: 15, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Humans; Hyperbilirubinemia; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Time Factors

2009
Time from diagnosis to treatment initiation predicts survival in younger, but not older, acute myeloid leukemia patients.
    Blood, 2009, Jan-01, Volume: 113, Issue:1

    Topics: Adolescent; Adult; Age Distribution; Age Factors; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Cytarabine; Databases, Factual; Emergency Medical Services; Humans; Leukemia, Myeloid, Acute; Middle Aged; Multivariate Analysis; Predictive Value of Tests; Prognosis; Remission Induction; Risk Factors; Survival Analysis; Time Factors; Young Adult

2009
AraU accumulation in patients with renal insufficiency as a potential mechanism for cytarabine neurotoxicity.
    International journal of hematology, 2008, Volume: 88, Issue:4

    Topics: Aged; Antimetabolites, Antineoplastic; Arabinofuranosyluracil; Cytarabine; Female; Half-Life; Humans; Kidney Failure, Chronic; Leukemia, Myeloid, Acute; Male; Middle Aged; Neurotoxicity Syndromes

2008
Triptolide cooperates with chemotherapy to induce apoptosis in acute myeloid leukemia cells.
    Experimental hematology, 2008, Volume: 36, Issue:12

    Topics: Annexin A5; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cytarabine; Diterpenes; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Epoxy Compounds; Humans; I-kappa B Proteins; Idarubicin; Leukemia, Myeloid, Acute; Leukocyte Common Antigens; Phenanthrenes; X-Linked Inhibitor of Apoptosis Protein

2008
[Efficiency of GHA priming chemotherapy on patients with refractory acute myeloid leukemia and myelodysplastic syndrome and its relationship with expression of costimulatory molecule B7.1].
    Zhongguo shi yan xue ye xue za zhi, 2008, Volume: 16, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; B7-1 Antigen; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Harringtonines; Homoharringtonine; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Treatment Outcome

2008
Practice of central nervous system prophylaxis and treatment in acute leukemias in Spain. Prospective registry study.
    Medicina clinica, 2008, Oct-04, Volume: 131, Issue:11

    Topics: Adolescent; Adult; Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Cytarabine; Drug Therapy, Combination; Female; Humans; Hydrocortisone; Injections, Spinal; Leukemia, Myeloid, Acute; Liposomes; Longitudinal Studies; Male; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Registries; Spain

2008
Human leukocyte antigen-DR negative de novo acute myeloid leukemia with Philadelphia chromosome.
    International journal of hematology, 2008, Volume: 88, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; HLA-DR Antigens; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Philadelphia Chromosome; Remission Induction

2008
Cytidine deaminase genotype and toxicity of cytosine arabinoside therapy in children with acute myeloid leukemia.
    British journal of haematology, 2009, Volume: 144, Issue:3

    Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Case-Control Studies; Child; Child, Preschool; Cytarabine; Cytosine Deaminase; Ethnicity; Genotype; Humans; Infant; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Randomized Controlled Trials as Topic; Survival Rate; Young Adult

2009
[Granulocytic sarcoma of the prostate presenting with urinary obstruction which progressed to acute myeloid leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2008, Volume: 49, Issue:11

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease Progression; Dysuria; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Neoplasms, Second Primary; Prostatic Neoplasms; Remission Induction; Sarcoma, Myeloid

2008
Fludarabine and cytarabine combined chemotherapy followed by transfusion of donor blood stem cells for treating relapse of acute leukaemia after allogeneic haematopoietic stem cell transplantation.
    Chinese medical journal, 2008, Sep-20, Volume: 121, Issue:18

    Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Transplantation, Homologous; Vidarabine

2008
[Relationship between the expression of the genes encoding the key enzymes for cytarabine metabolism and the pharmacokinetics of cytarabine in the treatment of childhood acute leukemia with high-dose cytarabine].
    Zhonghua er ke za zhi = Chinese journal of pediatrics, 2008, Volume: 46, Issue:4

    Topics: Antimetabolites, Antineoplastic; Child; Cytarabine; Cytidine Deaminase; Deoxycytidine Kinase; Gene Expression; Humans; Leukemia; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Precursor Cell Lymphoblastic Leukemia-Lymphoma

2008
Complex t(2;21;8)(p12;q22;q22): a variant t(8;21) in a patient with acute myeloid leukemia (AML-M2).
    Cancer genetics and cytogenetics, 2009, Jan-15, Volume: 188, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cerebral Hemorrhage; Chromosomes, Human, Pair 2; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Core Binding Factor Alpha 2 Subunit; Cytarabine; Fatal Outcome; Female; Humans; Karyotyping; Leukemia, Myeloid, Acute; Mitoxantrone; Oncogene Proteins, Fusion; Proto-Oncogene Proteins; RUNX1 Translocation Partner 1 Protein; Transcription Factors; Translocation, Genetic

2009
Inappropriate antidiuretic hormone production by leukaemic blasts in acute myeloid leukaemia.
    British journal of haematology, 2009, Volume: 145, Issue:5

    Topics: Adult; Antineoplastic Agents; Cytarabine; Fatty Liver; Female; Granulocyte Precursor Cells; Humans; Immunohistochemistry; Leukemia, Myeloid, Acute; Liver; Tomography, X-Ray Computed; Vasopressins

2009
The effect of cantharidins on leukemic stem cells.
    International journal of cancer, 2009, May-01, Volume: 124, Issue:9

    Topics: Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Apoptosis; Arylamine N-Acetyltransferase; Basic-Leucine Zipper Transcription Factors; Bridged Bicyclo Compounds, Heterocyclic; Cantharidin; Caspases; Cell Cycle; Colony-Forming Units Assay; Cytarabine; Daunorubicin; Enzyme Inhibitors; Female; Fetal Blood; Humans; Leukemia, Myeloid, Acute; Luminescence; Mice; Mice, Inbred NOD; Mice, SCID; Neoplastic Stem Cells; Phosphorylation; Proto-Oncogene Proteins c-myc; Snail Family Transcription Factors; STAT5 Transcription Factor; Stromal Cells; Survival Rate; Transcription Factors; Transplantation, Heterologous; Tumor Suppressor Protein p53

2009
Prognostic significance of beta-catenin and topoisomerase IIalpha in de novo acute myeloid leukemia.
    American journal of hematology, 2009, Volume: 84, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antigens, Neoplasm; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; beta Catenin; Biomarkers, Tumor; Cohort Studies; Comorbidity; Cytarabine; DNA Topoisomerases, Type II; DNA-Binding Proteins; Female; Humans; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Proteins; Prognosis; Retrospective Studies; Risk Factors; Survival Analysis; Wnt Proteins

2009
Life-threatening conjunctival presentation of myeloid sarcoma.
    Clinical & experimental ophthalmology, 2008, Volume: 36, Issue:8

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Conjunctival Neoplasms; Cytarabine; Etoposide; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Middle Aged; Neoplasms, Second Primary; Sarcoma, Myeloid; Skin Neoplasms

2008
Successful treatment of severe gastrointestinal bleeding after chemotherapy in acute myeloblastic leukemia with recombinant activated factor VII : report on one case and review of other uses in acute leukemias.
    Medical oncology (Northwood, London, England), 2010, Volume: 27, Issue:1

    Topics: Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Factor VIIa; Female; Gastrointestinal Hemorrhage; Humans; Idarubicin; Injections, Intravenous; Leukemia, Myeloid, Acute; Recombinant Proteins; Remission Induction; Thrombocytopenia; Treatment Outcome

2010
Existing and emerging therapeutic options for the treatment of acute myeloid leukemia.
    Clinical advances in hematology & oncology : H&O, 2008, Volume: 6, Issue:11

    Topics: Adenine; Adenine Nucleotides; Aminoglycosides; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Arabinonucleosides; Carbazoles; Clofarabine; Cytarabine; Dasatinib; Daunorubicin; fms-Like Tyrosine Kinase 3; Furans; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Naphthalimides; Organophosphonates; Prognosis; Protein Kinase Inhibitors; Pyrimidines; Sesquiterpenes; Staurosporine; Stem Cell Transplantation; Thiazoles; Tretinoin

2008
Future research directions for the treatment of AML.
    Clinical advances in hematology & oncology : H&O, 2008, Volume: 6, Issue:11

    Topics: Antineoplastic Agents; Azacitidine; Biomedical Research; Carbazoles; Carboplatin; Cytarabine; Daunorubicin; Decitabine; Enzyme Inhibitors; Etoposide; Flavonoids; Furans; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Piperidines; Quinolones; Staurosporine; Topotecan; Tretinoin

2008
Acute myelogenous leukemia presenting as acute infectious meningitis in a 7-year-old boy.
    Clinical pediatrics, 2009, Volume: 48, Issue:4

    Topics: Aminoglycosides; Anti-Bacterial Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Bone Marrow; Ceftriaxone; Child; Chromosomes, Human, Pair 10; Cytarabine; Daunorubicin; Diagnosis, Differential; Escherichia coli Infections; Etoposide; Flow Cytometry; Gemtuzumab; Humans; Injections, Spinal; Leukemia, Myeloid, Acute; Male; Meningitis, Bacterial; Patient Transfer; Spinal Puncture; Trisomy

2009
Successful administration of cytarabine in a 16-month-old girl with acute myelogenous leukemia and cytarabine syndrome.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2009, Volume: 102, Issue:2

    Topics: Cytarabine; Diphenhydramine; Drug Hypersensitivity; Female; Histamine Antagonists; Humans; Immunosuppressive Agents; Infant; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Methylprednisolone; Premedication; Ranitidine; Syndrome; Treatment Outcome

2009
Continuous 24-h monitoring of electrocardiogram during anthracycline-based therapy in acute leukemia.
    Leukemia research, 2009, Volume: 33, Issue:8

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cardiotoxins; Cytarabine; Daunorubicin; Electrocardiography; Female; Heart Diseases; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Monitoring, Physiologic

2009
[Relapsed acute myeloid leukemia with Down syndrome showing long disease-free survival after bone marrow transplantation].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2009, Volume: 50, Issue:2

    Topics: Adolescent; Antimetabolites, Antineoplastic; Bone Marrow Transplantation; Chromosomes, Human, Pair 7; Cytarabine; Disease-Free Survival; Down Syndrome; GATA1 Transcription Factor; Humans; Leukemia, Myeloid, Acute; Male; Monosomy; Mutation; Recurrence; Remission Induction; Risk; Time Factors

2009
Effect of cloretazine (VNP40101M) on acute myeloid leukaemia blast cells in vitro as a single agent and combined with cytarabine and daunorubicin.
    Leukemia research, 2009, Volume: 33, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Hydrazines; Leukemia, Myeloid, Acute; Sulfonamides

2009
Defective expression of deoxycytidine kinase in cytarabine-resistant acute myeloid leukemia cells.
    International journal of oncology, 2009, Volume: 34, Issue:4

    Topics: Antimetabolites, Antineoplastic; Cell Line, Tumor; Cytarabine; Deoxycytidine Kinase; DNA Fragmentation; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Leukemic; Humans; Leukemia, Myeloid, Acute; Models, Biological; Oligonucleotide Array Sequence Analysis; Phenotype

2009
Auto-SCT for AML in second remission: CALGB study 9620.
    Bone marrow transplantation, 2009, Volume: 44, Issue:6

    Topics: Adult; Aged; Aging; Antigens, CD34; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Etoposide; Female; Humans; Ideal Body Weight; Infusions, Intravenous; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Peripheral Blood Stem Cell Transplantation; Remission Induction; Transplantation, Autologous; Treatment Outcome; Treatment Refusal; Young Adult

2009
A LC-MS/MS method for the analysis of intracellular nucleoside triphosphate levels.
    Pharmaceutical research, 2009, Volume: 26, Issue:6

    Topics: Antimetabolites, Antineoplastic; Bone Marrow Cells; Cell Line, Tumor; Chromatography, Liquid; Cytarabine; Humans; Leukemia; Leukemia, Myeloid, Acute; Linear Models; Nucleotides; Oligodeoxyribonucleotides; Sensitivity and Specificity; Tandem Mass Spectrometry

2009
Cytarabine-associated lymphoid dyscrasia with atypical T CD30+ infiltrate in a patient suffering from acute nonlymphoblastic leukaemia.
    The British journal of dermatology, 2009, Volume: 160, Issue:5

    Topics: Chronic Disease; Cytarabine; Female; Humans; Immunosuppressive Agents; Ki-1 Antigen; Leukemia, Myeloid, Acute; Middle Aged; Skin Diseases

2009
Laromustine: the return of alkylators to non-myeloablative therapy of AML.
    Leukemia research, 2009, Volume: 33, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Hydrazines; Leukemia, Myeloid, Acute; Sulfonamides

2009
Biphenotypic acute leukemia treated with acute myeloid leukemia regimens: a case series.
    Journal of the National Medical Association, 2009, Volume: 101, Issue:3

    Topics: Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Biomarkers; Case-Control Studies; Cytarabine; Female; Humans; Idarubicin; Immunophenotyping; Leukemia, Biphenotypic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Retrospective Studies

2009
Severe Henoch-Schönlein purpura induced by cytarabine.
    The Annals of pharmacotherapy, 2009, Volume: 43, Issue:4

    Topics: Adult; Cytarabine; Humans; IgA Vasculitis; Leukemia, Myeloid, Acute; Male; Severity of Illness Index

2009
Intracellular cytarabine triphosphate production correlates to deoxycytidine kinase/cytosolic 5'-nucleotidase II expression ratio in primary acute myeloid leukemia cells.
    Biochemical pharmacology, 2009, Jun-15, Volume: 77, Issue:12

    Topics: 5'-Nucleotidase; Arabinofuranosylcytosine Triphosphate; Cytarabine; Deoxycytidine Kinase; Drug Resistance, Neoplasm; Equilibrative Nucleoside Transporter 1; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Predictive Value of Tests; RNA, Messenger

2009
An uncommon cause of small bowel obstruction: isolated primary granulocytic sarcoma.
    QJM : monthly journal of the Association of Physicians, 2009, Volume: 102, Issue:7

    Topics: Antineoplastic Agents; Cytarabine; Female; Humans; Idarubicin; Intestinal Obstruction; Intestine, Small; Leukemia, Myeloid, Acute; Middle Aged; Sarcoma, Myeloid; Tomography, X-Ray Computed; Treatment Outcome

2009
Survival is poorer in patients with secondary core-binding factor acute myelogenous leukemia compared with de novo core-binding factor leukemia.
    Cancer, 2009, Jul-15, Volume: 115, Issue:14

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Core Binding Factors; Cytarabine; Disease-Free Survival; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasms, Second Primary; Survival Analysis; Translocation, Genetic

2009
pH-sensitive immunoliposomes specific to the CD33 cell surface antigen of leukemic cells.
    International journal of pharmaceutics, 2009, Nov-03, Volume: 381, Issue:2

    Topics: Acrylamides; Acrylic Resins; Alkylation; Antibodies, Monoclonal; Antibody Affinity; Antibody Specificity; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Biological Availability; Cell Line, Tumor; Cell Survival; Cold Temperature; Cytarabine; Dose-Response Relationship, Drug; Drug Delivery Systems; Drug Stability; Endocytosis; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Immunoconjugates; Leukemia, Myeloid, Acute; Liposomes; Polymethacrylic Acids; Sialic Acid Binding Ig-like Lectin 3

2009
Enhanced invasiveness of drug-resistant acute myeloid leukemia cells through increased expression of matrix metalloproteinase-2.
    International journal of cancer, 2009, Sep-01, Volume: 125, Issue:5

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Benzopyrans; Blast Crisis; Blotting, Western; Cytarabine; Doxorubicin; Drug Resistance, Neoplasm; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Matrix Metalloproteinase 2; Middle Aged; Neoplasm Invasiveness; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured; Young Adult

2009
SNP analyses in cytarabine metabolizing enzymes in AML patients and their impact on treatment response and patient survival: identification of CDA SNP C-451T as an independent prognostic parameter for survival.
    Leukemia, 2009, Volume: 23, Issue:10

    Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Cytarabine; Cytidine Deaminase; Deoxycytidine Kinase; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Nucleoside Deaminases; Polymorphism, Single Nucleotide; Prognosis; Survival Rate; Treatment Outcome; Young Adult

2009
Myeloid disease.
    Current opinion in hematology, 2009, Volume: 16, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Myeloproliferative Disorders

2009
Intensive induction chemotherapy with regimen containing intermediate dose cytarabine in the treatment of de novo acute myeloid leukemia.
    American journal of hematology, 2009, Volume: 84, Issue:7

    Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Female; Harringtonines; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Remission Induction; Young Adult

2009
The clinical outcome of FLAG chemotherapy without idarubicin in patients with relapsed or refractory acute myeloid leukemia.
    Journal of Korean medical science, 2009, Volume: 24, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Treatment Outcome; Vidarabine

2009
Inhibition of MEK signaling enhances the ability of cytarabine to induce growth arrest and apoptosis of acute myelogenous leukemia cells.
    Apoptosis : an international journal on programmed cell death, 2009, Volume: 14, Issue:9

    Topics: Apoptosis; Benzimidazoles; Cell Cycle; Cell Cycle Proteins; Cell Differentiation; Cell Proliferation; Cytarabine; DNA Damage; Drug Synergism; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Leukemic; Histones; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases

2009
Chelation of intracellular iron with the antifungal agent ciclopirox olamine induces cell death in leukemia and myeloma cells.
    Blood, 2009, Oct-01, Volume: 114, Issue:14

    Topics: Animals; Antifungal Agents; Antimetabolites, Antineoplastic; Apoptosis; Cells, Cultured; Ciclopirox; Cytarabine; Drug Synergism; Electron Spin Resonance Spectroscopy; Fibroblasts; Humans; Immunoblotting; Inhibitor of Apoptosis Proteins; Iron; Iron Chelating Agents; Leukemia, Myeloid, Acute; Luciferases; Lung; Mice; Mice, Inbred NOD; Mice, SCID; Microtubule-Associated Proteins; Multiple Myeloma; Promoter Regions, Genetic; Pyridones; Ribonucleotide Reductases; Survivin

2009
Risk-stratified therapy and the intensive use of cytarabine improves the outcome in childhood acute myeloid leukemia: the AML99 trial from the Japanese Childhood AML Cooperative Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Aug-20, Volume: 27, Issue:24

    Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Child, Preschool; Cytarabine; Female; Hematopoietic Stem Cell Transplantation; Humans; Infant; Leukemia, Myeloid, Acute; Male; Transplantation, Homologous

2009
The FLT3 inhibitor tandutinib (formerly MLN518) has sequence-independent synergistic effects with cytarabine and daunorubicin.
    Cell cycle (Georgetown, Tex.), 2009, Aug-15, Volume: 8, Issue:16

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Apoptosis; Cell Line; Cell Proliferation; Cytarabine; Daunorubicin; Drug Synergism; Flow Cytometry; fms-Like Tyrosine Kinase 3; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Piperazines; Quinazolines

2009
A homoharringtonine-based induction regimen for the treatment of elderly patients with acute myeloid leukemia: a single center experience from China.
    Journal of hematology & oncology, 2009, Jul-30, Volume: 2

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; China; Cytarabine; Drug Administration Schedule; Harringtonines; Homoharringtonine; Humans; Leukemia, Myeloid, Acute; Middle Aged; Remission Induction; Retrospective Studies; Survival Analysis

2009
Acute myeloid leukemia and Langerhans' cell histiocytosis: multiple theories for an unusual presentation.
    Leukemia research, 2010, Volume: 34, Issue:3

    Topics: Aged, 80 and over; Antineoplastic Agents; Chromosomes, Human, Pair 8; Cytarabine; Histiocytosis, Langerhans-Cell; Humans; Leukemia, Myeloid, Acute; Male; Neoplasms, Second Primary; Trisomy

2010
Acute myeloid leukemia complicating multiple myeloma: a case successfully treated with etoposide, thioguanine, and cytarabine.
    Clinical lymphoma & myeloma, 2009, Volume: 9, Issue:4

    Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Etoposide; Female; Humans; Injections, Subcutaneous; Leukemia, Myeloid, Acute; Multiple Myeloma; Remission Induction; Thioguanine

2009
Synergistic effect of inhibiting translation initiation in combination with cytotoxic agents in acute myelogenous leukemia cells.
    Leukemia research, 2010, Volume: 34, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biphenyl Compounds; Cell Line, Tumor; Cytarabine; Cytotoxins; Daunorubicin; Drug Evaluation, Preclinical; Drug Synergism; Etoposide; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Models, Biological; Nitrophenols; Peptide Initiation Factors; Piperazines; Protein Biosynthesis; Protein Synthesis Inhibitors; Sulfonamides; Triterpenes; U937 Cells

2010
A new pattern of cytosine-arabinoside-induced lung toxicity.
    British journal of haematology, 2009, Volume: 147, Issue:5

    Topics: Adult; Alveolitis, Extrinsic Allergic; Antimetabolites, Antineoplastic; Cytarabine; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Tomography, X-Ray Computed; Young Adult

2009
A comparative study of outcomes of idarubicin- and etoposide-intensified conditioning regimens for allogeneic peripheral blood stem cell transplantation in patients with high-risk acute leukemia.
    Acta pharmacologica Sinica, 2009, Volume: 30, Issue:10

    Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Aspergillus; Busulfan; China; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Disease-Free Survival; Etoposide; Female; Graft Survival; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Hydroxyurea; Idarubicin; Immunosuppressive Agents; Leukemia; Leukemia, Myeloid, Acute; Male; Methylprednisolone; Mucositis; Pneumonia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Premedication; Retrospective Studies; Risk Factors; Semustine; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Whole-Body Irradiation

2009
Successful treatment of congenital acute myeloid leukemia (AML-M6) in a premature infant.
    Journal of pediatric hematology/oncology, 2009, Volume: 31, Issue:11

    Topics: Antimetabolites, Antineoplastic; Cytarabine; Female; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Leukemia, Myeloid, Acute; Remission Induction

2009
Severe anterior uveitis as a complication of high-dose cytosine-arabinoside.
    Acta ophthalmologica, 2009, Volume: 87, Issue:8

    Topics: Administration, Topical; Adult; Antimetabolites, Antineoplastic; Cytarabine; Dexamethasone; Drug Administration Schedule; Female; Glucocorticoids; Humans; Leukemia, Myeloid, Acute; Mydriatics; Uveitis, Anterior

2009
Salvage therapy for acute myeloid leukemia with fludarabine, cytarabine, and idarubicin with or without gemtuzumab ozogamicin and with concurrent or sequential G-CSF.
    American journal of hematology, 2009, Volume: 84, Issue:11

    Topics: Adolescent; Adult; Aged; Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Evaluation; Female; Gemtuzumab; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Retrospective Studies; Salvage Therapy; Survival Analysis; Treatment Outcome; Vidarabine; Young Adult

2009
Quantifying the survival benefit for allogeneic hematopoietic stem cell transplantation in relapsed acute myelogenous leukemia.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2009, Volume: 15, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Hematopoietic Stem Cell Transplantation; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Middle Aged; Recurrence; Remission Induction; Retrospective Studies; Salvage Therapy; Transplantation Conditioning; Transplantation, Homologous; Whole-Body Irradiation

2009
Targeted delivery of antisense oligodeoxynucleotide by transferrin conjugated pH-sensitive lipopolyplex nanoparticles: a novel oligonucleotide-based therapeutic strategy in acute myeloid leukemia.
    Molecular pharmaceutics, 2010, Feb-01, Volume: 7, Issue:1

    Topics: Antimetabolites, Antineoplastic; Base Sequence; Cell Line, Tumor; Cryoelectron Microscopy; Cytarabine; Down-Regulation; Drug Delivery Systems; Genetic Therapy; Humans; Hydrogen-Ion Concentration; K562 Cells; Leukemia, Myeloid, Acute; Nanoparticles; Oligodeoxyribonucleotides; Oligodeoxyribonucleotides, Antisense; Receptors, Transferrin; Ribonucleotide Reductases; RNA, Messenger; RNA, Neoplasm; Transferrin; Tumor Cells, Cultured

2010
FLT3-ITD induces ara-C resistance in myeloid leukemic cells through the repression of the ENT1 expression.
    Biochemical and biophysical research communications, 2009, Dec-18, Volume: 390, Issue:3

    Topics: Antimetabolites, Antineoplastic; Cell Line, Tumor; Cytarabine; Down-Regulation; Equilibrative Nucleoside Transporter 1; fms-Like Tyrosine Kinase 3; Gene Expression Regulation, Leukemic; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Leukemia, Myeloid, Acute; Promoter Regions, Genetic

2009
Successful treatment of Hodgkin lymphoma and acute leukemia.
    Leukemia & lymphoma, 2010, Volume: 51, Issue:1

    Topics: Adult; Biopsy; Bone Marrow Cells; Cytarabine; Hodgkin Disease; Humans; Idarubicin; Leukemia, Myeloid, Acute; Lymphatic Metastasis; Male; Neoplasms, Second Primary; Remission Induction

2010
Topoisomerase IIalpha expression in acute myeloid leukaemia cells that survive after exposure to daunorubicin or ara-C.
    Oncology reports, 2009, Volume: 22, Issue:6

    Topics: Antibiotics, Antineoplastic; Antigens, Neoplasm; Antimetabolites, Antineoplastic; Cell Cycle; Cell Survival; Cytarabine; Daunorubicin; DNA Topoisomerases, Type II; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Gene Expression Regulation, Leukemic; Humans; Leukemia, Myeloid, Acute; Time Factors

2009
Oncogenic RAS enables DNA damage- and p53-dependent differentiation of acute myeloid leukemia cells in response to chemotherapy.
    PloS one, 2009, Nov-05, Volume: 4, Issue:11

    Topics: Antineoplastic Agents; Apoptosis; Bone Marrow Cells; Cell Differentiation; Cell Proliferation; Cellular Senescence; Cytarabine; Daunorubicin; Etoposide; Genes, ras; Humans; Leukemia, Myeloid, Acute; Mutation; ras Proteins; Tumor Suppressor Protein p53

2009
Molecular identification of phaeohyphomycosis due to Alternaria infectoria in a patient with acute myeloid leukemia--a case report.
    Diagnostic microbiology and infectious disease, 2010, Volume: 66, Issue:3

    Topics: Adolescent; Alternaria; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Immunocompromised Host; Leukemia, Myeloid, Acute; Mycoses; Nasal Cavity; Polymerase Chain Reaction; Rhinitis; Vidarabine

2010
Jumping translocation involving 1q21 during long-term complete remission of acute myeloid leukemia.
    Annals of hematology, 2010, Volume: 89, Issue:7

    Topics: Adult; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 1; Cytarabine; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Recurrence; Time Factors; Translocation, Genetic

2010
[Successful induction of complete remission by gemtuzumab ozogamicin following chemotherapy in three patients with relapsed or refractory acute myeloid leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2009, Volume: 50, Issue:8

    Topics: Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Female; Gemtuzumab; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Recurrence; Remission Induction; Vidarabine

2009
Mees lines and Beau lines after chemotherapy.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2010, Feb-23, Volume: 182, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cytarabine; Daunorubicin; Docetaxel; Female; Humans; Leukemia, Myeloid, Acute; Nail Diseases; Taxoids

2010
Multiple hepatocellular carcinomas developed 15 months after commencement of chemotherapy for elderly acute myelogenous leukemia.
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2009, Volume: 50, Issue:11

    Topics: Aclarubicin; Aged; Androgen Antagonists; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cytarabine; Fatal Outcome; Granulocyte Colony-Stimulating Factor; Hemochromatosis; Humans; Leukemia, Myeloid, Acute; Liver Neoplasms; Male; Neoplasms, Second Primary; Prostatic Neoplasms; Time Factors

2009
"I am older, not elderly," said the patient with acute myeloid leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Feb-01, Volume: 28, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Mercaptopurine

2010
Idarubicin plus behenoyl cytarabine and 6-thioguanine compares favorably with idarubicin plus cytarabine-based regimen for children with previously untreated acute myeloid leukemia: 10-year retrospective, multicenter study in Korea.
    Journal of Korean medical science, 2010, Volume: 25, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Cytogenetics; Female; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Male; Republic of Korea; Retrospective Studies; Survival Analysis; Thioguanine; Young Adult

2010
Intrathecal chemotherapy and meningeal relapses in myelomonocytic AML. A single institution experience.
    American journal of hematology, 2010, Volume: 85, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Idarubicin; Injections, Spinal; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemic Infiltration; Male; Meninges; Middle Aged; Mitoxantrone; Testis; Young Adult

2010
Typhlitis due to mucormycosis after chemotherapy in a patient with acute myeloid leukemia.
    Leukemia research, 2010, Volume: 34, Issue:7

    Topics: Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Digestive System Surgical Procedures; Enterococcus faecium; Fatal Outcome; Female; Gram-Positive Bacterial Infections; Humans; Idarubicin; Leukemia, Myeloid, Acute; Middle Aged; Mucormycosis; Neutropenia; Rhinitis; Shock, Septic; Sinusitis; Typhlitis

2010
Toxicity of laromustine plus high-dose cytarabine in patients with relapsed acute myeloid leukemia.
    Blood, 2010, Jan-14, Volume: 115, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Double-Blind Method; Female; Humans; Hydrazines; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Remission Induction; Sulfonamides

2010
Advantage of MIDAM protocol in treatment of elderly patients with refractory and relapsing acute myeloid leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Mar-01, Volume: 28, Issue:7

    Topics: Aged; Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Resistance, Neoplasm; Gemtuzumab; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Recurrence

2010
Early reduction of WT1 transcripts during induction chemotherapy predicts for longer disease free and overall survival in acute myeloid leukemia.
    Haematologica, 2010, Volume: 95, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Cytarabine; Disease-Free Survival; Female; Genes, Wilms Tumor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Predictive Value of Tests; Survival Rate; Time Factors; Transcription, Genetic; Treatment Outcome; WT1 Proteins; Young Adult

2010
Brucellosis: a rare cause of febrile neutropenia in acute myeloblastic leukemia.
    Medical oncology (Northwood, London, England), 2011, Volume: 28, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brucellosis; Cytarabine; Diagnosis, Differential; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Neutropenia; Prognosis; Remission Induction

2011
[Patients older than 80 years with de novo acute myeloid leukemias without erythroblastic and/or megakaryocytic dysplasia achieve complete remission and longer survival after classical chemotherapy 3 + 7].
    Vnitrni lekarstvi, 2010, Volume: 56, Issue:1

    Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Erythroblasts; Female; Humans; Leukemia, Myeloid, Acute; Male; Megakaryocytes; Mitoxantrone; Remission Induction; Survival Rate

2010
Re-analysis of the outcomes of post-remission therapy for acute myeloid leukemia with core binding factor according to years of patient enrollment.
    Japanese journal of clinical oncology, 2010, Volume: 40, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Core Binding Factors; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Stem Cell Transplantation; Survival Rate; Young Adult

2010
Targeting integrin linked kinase and FMS-like tyrosine kinase-3 is cytotoxic to acute myeloid leukemia stem cells but spares normal progenitors.
    Leukemia research, 2010, Volume: 34, Issue:10

    Topics: Adult; Aged; Animals; Azo Compounds; Cells, Cultured; Cytarabine; Daunorubicin; Female; fms-Like Tyrosine Kinase 3; Glycogen Synthase Kinase 3; Humans; Leukemia, Myeloid, Acute; Male; Mice; Mice, Inbred NOD; Middle Aged; Neoplastic Stem Cells; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyrazoles; RNA, Small Interfering; Stem Cells

2010
Late relapses in acute myeloid leukemia: analysis of characteristics and outcome.
    Leukemia & lymphoma, 2010, Volume: 51, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Medical Records; Middle Aged; Neoplasm Recurrence, Local; Remission Induction; Survival Rate; Treatment Outcome; Young Adult

2010
Toxic shock syndrome caused by hospital-acquired methicillin-resistant Staphylococcus aureus in a patient with pancytopenia.
    Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine, 2010, Volume: 12, Issue:1

    Topics: Adult; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Cross Infection; Cytarabine; Etoposide; Fatal Outcome; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Methicillin-Resistant Staphylococcus aureus; Multiple Organ Failure; Pancytopenia; Shock, Septic; Staphylococcal Infections

2010
[Distribution of WHO subtypes, initial treatment outcomes and prognosis study of 623 unselected adult patients with acute myeloid leukaemia in Shanghai.].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2010, Volume: 31, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; China; Cytarabine; Humans; Leukemia, Myeloid, Acute; Prognosis; Treatment Outcome

2010
Cytosine-arabinoside-induced keratopathy: a model of corneal proliferation kinetics.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 2010, Volume: 224, Issue:5

    Topics: Antimetabolites, Antineoplastic; Cell Proliferation; Corneal Diseases; Cytarabine; Epithelium, Corneal; Female; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Microscopy, Confocal; Middle Aged; Models, Biological; Prospective Studies

2010
Sequential flavopiridol, mitoxantrone and cytosine arabinoside for newly diagnosed poor risk acute myeloid leukemia. What to do next?
    Leukemia research, 2010, Volume: 34, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase II as Topic; Combined Modality Therapy; Cytarabine; Drug Administration Schedule; Flavonoids; Follow-Up Studies; Forecasting; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Piperidines; Risk; Treatment Outcome; Tumor Lysis Syndrome

2010
Orbital mass as a presenting sign of acute leukemia.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2010, Volume: 45, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Fatal Outcome; Female; Humans; Idarubicin; Infant; Leukemia, Myeloid, Acute; Magnetic Resonance Imaging; Orbital Neoplasms

2010
Central line-associated bacteremia caused by drug-resistant Staphylococcus caprae after chemotherapy for acute myelogenous leukemia.
    International journal of hematology, 2010, Volume: 91, Issue:5

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bacteremia; Cytarabine; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Middle Aged; Staphylococcus

2010
Neurological complications during treatment of childhood cancer: mind Wernicke encephalopathy.
    Pediatric hematology and oncology, 2010, Volume: 27, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Magnetic Resonance Imaging; Male; Mercaptopurine; Methotrexate; Prednisone; Radiography; Vincristine; Wernicke Encephalopathy

2010
Advances in the management of acute myeloid leukemia in older adult patients.
    Oncology nursing forum, 2010, Volume: 37, Issue:3

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Decitabine; Humans; Leukemia, Myeloid, Acute; Middle Aged; Nurse's Role; Nursing Assessment; Oncology Nursing; Patient Education as Topic; Practice Guidelines as Topic; Prognosis; Quality of Life; Social Support; Stem Cell Transplantation

2010
Homologous recombination as a resistance mechanism to replication-induced double-strand breaks caused by the antileukemia agent CNDAC.
    Blood, 2010, Sep-09, Volume: 116, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Cell Line; Cell Line, Tumor; Cell Survival; CHO Cells; Cricetinae; Cricetulus; Cytarabine; DNA Breaks, Double-Stranded; DNA Replication; DNA, Single-Stranded; Drug Resistance; Female; HCT116 Cells; HeLa Cells; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recombination, Genetic; Sister Chromatid Exchange; Young Adult

2010
Addition of lomustine to idarubicin and cytarabine improves the outcome of elderly patients with de novo acute myeloid leukemia: a report from the GOELAMS.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Jun-20, Volume: 28, Issue:18

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Cytarabine; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Lomustine; Male; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Remission Induction; Retrospective Studies; Survival Rate; Treatment Outcome

2010
Leukemia cutis limited to the needle puncture sites.
    The Journal of dermatology, 2010, Volume: 37, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Cytarabine; Fatal Outcome; Humans; Idarubicin; Leukemia, Myeloid, Acute; Leukemic Infiltration; Male; Skin Neoplasms

2010
Deoxycytidine kinase is downregulated in Ara-C-resistant acute myeloid leukemia murine cell lines.
    Leukemia, 2010, Volume: 24, Issue:8

    Topics: Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Cytarabine; Deoxycytidine Kinase; Down-Regulation; Drug Resistance, Neoplasm; Leukemia, Myeloid, Acute; Mice

2010
Prospective cytomegalovirus monitoring during first-line chemotherapy in patients with acute myeloid leukemia.
    Journal of medical virology, 2010, Volume: 82, Issue:7

    Topics: Adult; Antibiotics, Antineoplastic; Antibodies, Viral; Antigens, Viral; Antineoplastic Agents; Antiviral Agents; Cytarabine; Cytomegalovirus; Cytomegalovirus Infections; Daunorubicin; Female; Humans; Hydroxyurea; Incidence; Italy; Leukemia, Myeloid, Acute; Male; Middle Aged; Monitoring, Physiologic; Phosphoproteins; Treatment Outcome; Viral Matrix Proteins; Young Adult

2010
Molecular responses during chemotherapy in acute myeloid leukemias in predicting poor-response to standard chemotherapy.
    The Malaysian journal of pathology, 2009, Volume: 31, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Agents; Apoptosis; Child; Child, Preschool; Cytarabine; Cytokines; Daunorubicin; Drug Resistance, Neoplasm; Elafin; Female; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitogen-Activated Protein Kinases; Prognosis; Receptors, TNF-Related Apoptosis-Inducing Ligand; Remission Induction; RNA, Messenger; Signal Transduction; Young Adult

2009
[Prognostic factors and therapeutic strategies for acute myeloid leukemia].
    Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2010, Volume: 39, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Humans; Leukemia, Myeloid, Acute; Prognosis

2010
Aurora-A kinase inhibition enhances the cytosine arabinoside-induced cell death in leukemia cells through apoptosis and mitotic catastrophe.
    Cancer letters, 2010, Nov-28, Volume: 297, Issue:2

    Topics: Apoptosis; Aurora Kinases; Caspases; Cell Cycle; Cell Death; Cell Line, Tumor; Cell Survival; Cytarabine; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Membrane Potential, Mitochondrial; Mitochondria; Mitosis; p38 Mitogen-Activated Protein Kinases; Protein Serine-Threonine Kinases; RNA, Small Interfering; Transfection

2010
Blood stream infections during chemotherapy-induced neutropenia in adult patients with acute myeloid leukemia: treatment cycle matters.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2010, Volume: 29, Issue:10

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Bacteria; Blood; Cytarabine; Female; Finland; Humans; Idarubicin; Incidence; Leukemia, Myeloid, Acute; Male; Middle Aged; Neutropenia; Prospective Studies; Sepsis; Thioguanine; Young Adult

2010
A single dose pegfilgrastim for supporting neutrophil recovery in patients treated for high-risk acute myeloid leukemia by the EMA 2000 schedule.
    Hematology (Amsterdam, Netherlands), 2010, Volume: 15, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Etoposide; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Neutropenia; Polyethylene Glycols; Prognosis; Recombinant Proteins; Remission Induction; Survival Analysis; Treatment Outcome; Young Adult

2010
Impact of weekend admissions on quality of care and outcomes in patients with acute myeloid leukemia.
    Cancer, 2010, Aug-01, Volume: 116, Issue:15

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Catheterization; Cytarabine; Female; Hospital Mortality; Hospitalization; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Patient Admission; Quality of Health Care; Remission Induction; Time Factors; Treatment Outcome

2010
Secondary adrenal insufficiency in an infant after intrathecal triple chemotherapy.
    Pediatric blood & cancer, 2010, Volume: 55, Issue:2

    Topics: Adrenal Insufficiency; Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Hydrocortisone; Immunosuppressive Agents; Injections, Spinal; Leukemia, Myeloid, Acute; Methotrexate; Recurrence

2010
Prognosis of secondary acute myeloid leukemia is affected by the type of the preceding hematologic disorders and the presence of trisomy 8.
    Japanese journal of clinical oncology, 2010, Volume: 40, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 8; Combined Modality Therapy; Cytarabine; Daunorubicin; Female; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Myeloproliferative Disorders; Prognosis; Remission Induction; Retrospective Studies; Survival Rate; Trisomy; Young Adult

2010
An unusual case of acute myeloid leukemia: late isolated testicular relapse followed by isolated central nervous system relapse.
    Pediatric blood & cancer, 2010, Dec-01, Volume: 55, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Child; Cytarabine; Daunorubicin; Humans; Immunoenzyme Techniques; In Situ Hybridization, Fluorescence; Injections, Spinal; Leukemia, Myeloid, Acute; Male; Neoplasm Recurrence, Local; Testicular Neoplasms; Thioguanine; Treatment Outcome

2010
A der(1)t(1;21)(p36.3;q22) in a patient with acute myelogenous leukemia M2.
    Acta haematologica, 2010, Volume: 124, Issue:1

    Topics: Chromosome Aberrations; Cytarabine; Daunorubicin; Female; Humans; In Situ Hybridization, Fluorescence; Leukemia, Myeloid, Acute; Middle Aged; Translocation, Genetic

2010
Questions regarding frontline therapy of acute myeloid leukemia.
    Cancer, 2010, Nov-01, Volume: 116, Issue:21

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Middle Aged; Neoplasm, Residual; Prognosis; Remission Induction; Retreatment

2010
Effect of post-remission chemotherapy preceding allogeneic hematopoietic cell transplant in patients with acute myeloid leukemia in first remission.
    Leukemia & lymphoma, 2010, Volume: 51, Issue:9

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Cytarabine; Cytogenetic Analysis; Daunorubicin; Female; Follow-Up Studies; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm, Residual; Remission Induction; Retrospective Studies; Survival Rate; Transplantation, Homologous; Treatment Outcome; Young Adult

2010
Systemic mastocytosis associated with acute myeloid leukaemia.
    Pathology, 2010, Volume: 42, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Marrow Cells; Chromosome Aberrations; Cytarabine; Cytogenetic Analysis; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Mast Cells; Mastocytosis, Systemic

2010
Acute intraoperative tumour lysis syndrome.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2010, Volume: 57, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Middle Aged; Postoperative Complications; Risk Factors; Time Factors; Tumor Lysis Syndrome

2010
Day 15 bone marrow driven double induction in young adult patients with acute myeloid leukemia: feasibility, toxicity, and therapeutic results.
    American journal of hematology, 2010, Volume: 85, Issue:9

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Bone Marrow; Chromosome Aberrations; Cytarabine; Disease-Free Survival; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Remission Induction; Retrospective Studies; Survival Rate; Time Factors; Transplantation, Homologous; Vidarabine; Young Adult

2010
Intensive chemotherapy does not benefit most older patients (age 70 years or older) with acute myeloid leukemia.
    Blood, 2010, Nov-25, Volume: 116, Issue:22

    Topics: Age Factors; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Cytarabine; Humans; Leukemia, Myeloid, Acute; Prognosis; Risk Factors; Survival Rate

2010
Fludarabine, cytarabine, granulocyte colony-stimulating factor, and idarubicin (FLAG-IDA) for the treatment of children with poor-prognosis acute leukemia: the Hacettepe experience.
    Pediatric hematology and oncology, 2010, Volume: 27, Issue:7

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Survival Rate; Treatment Outcome; Vidarabine

2010
Race and intensity of post-remission therapy in acute myeloid leukemia.
    Leukemia research, 2011, Volume: 35, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Black People; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Drug Resistance, Neoplasm; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Neoplasm Recurrence, Local; Remission Induction; Survival Rate; Time Factors; Treatment Outcome; White People; Young Adult

2011
Extramedullary tumors presenting double vision in patients with t(8;21)(q22;q22) acute myeloid leukemia lacking mutations in the receptor tyrosine kinase genes KIT or FLT3.
    Leukemia research, 2010, Volume: 34, Issue:12

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Blast Crisis; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Cytarabine; Diplopia; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Male; Paranasal Sinus Neoplasms; Proto-Oncogene Proteins c-kit; Stem Cell Transplantation; Translocation, Genetic; Transplantation, Homologous

2010
Peripheral blasts on day 21 of induction chemotherapy in a patient with core binding factor acute myeloid leukemia: more than meets the eye.
    Clinical lymphoma, myeloma & leukemia, 2010, Volume: 10, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Core Binding Factors; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Vidarabine

2010
FLANG salvage chemotherapy is an effective regimen that offers a safe bridge to transplantation for patients with relapsed or refractory acute myeloid leukemia.
    Medical oncology (Northwood, London, England), 2011, Volume: 28 Suppl 1

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Cytarabine; Female; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Neoplasm Recurrence, Local; Retrospective Studies; Salvage Therapy; Stem Cell Transplantation; Treatment Outcome; Vidarabine; Young Adult

2011
Ulcerated plaque under a ruby ring in an immunosuppressed patient.
    Dermatology online journal, 2010, Aug-15, Volume: 16, Issue:8

    Topics: Adenine Nucleotides; Aged; Antineoplastic Agents; Arabinonucleosides; Candida; Candidiasis, Cutaneous; Clofarabine; Cytarabine; Dermatologic Agents; Dermatomycoses; Fusarium; Humans; Immunocompromised Host; Itraconazole; Jewelry; Leukemia, Myeloid, Acute; Male; Pyrimidines; Skin Ulcer; Treatment Outcome; Triazoles; Voriconazole

2010
[A case of del(16)(q22) in a patient with acute myeloid leukemia with complex karyotype].
    The Korean journal of laboratory medicine, 2010, Volume: 30, Issue:4

    Topics: Antimetabolites, Antineoplastic; Chromosome Deletion; Chromosomes, Human, Pair 16; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; In Situ Hybridization, Fluorescence; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Monocyte-Macrophage Precursor Cells; Prognosis

2010
Early assessment of treatment response in patients with AML using [(18)F]FLT PET imaging.
    Leukemia research, 2011, Volume: 35, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Case-Control Studies; Cytarabine; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Positron-Emission Tomography; Radiopharmaceuticals; Survival Rate; Treatment Outcome; Young Adult

2011
BAALC and ERG expression levels are associated with outcome and distinct gene and microRNA expression profiles in older patients with de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study.
    Blood, 2010, Dec-16, Volume: 116, Issue:25

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cytarabine; Cytogenetic Analysis; Daunorubicin; Female; Gene Expression Profiling; Humans; Leukemia, Myeloid, Acute; Male; MicroRNAs; Middle Aged; Neoplasm Proteins; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Survival Rate; Trans-Activators; Transcriptional Regulator ERG; Treatment Outcome

2010
Sensitivity and gene expression profile of fresh human acute myeloid leukemia cells exposed ex vivo to AS602868.
    Cancer chemotherapy and pharmacology, 2011, Volume: 68, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Etoposide; Gene Expression Profiling; Humans; I-kappa B Proteins; Leukemia, Myeloid, Acute; Lymphocytes; Oligonucleotide Array Sequence Analysis; Pyrimidines

2011
Second-line mitoxantrone, etoposide, and cytarabine for acute myeloid leukemia: a single-center experience.
    American journal of hematology, 2010, Volume: 85, Issue:11

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Remission Induction; Retrospective Studies; Salvage Therapy; Survival Rate; Treatment Failure; Young Adult

2010
Dorsolateral midbrain MRI abnormalities and ocular motor deficits following cytarabine-based chemotherapy for acute myelogenous leukemia.
    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2011, Volume: 31, Issue:1

    Topics: Antimetabolites, Antineoplastic; Child; Cytarabine; Humans; Leukemia, Myeloid, Acute; Magnetic Resonance Imaging; Male; Mesencephalon; Ocular Motility Disorders; Time

2011
Anterior uveitis associated with high-dose cytosine arabinoside.
    Ocular immunology and inflammation, 2010, Volume: 18, Issue:6

    Topics: Adolescent; Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Prednisolone; Treatment Outcome; Uveitis, Anterior

2010
Mechanisms of synergistic antileukemic interactions between valproic acid and cytarabine in pediatric acute myeloid leukemia.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2010, Nov-15, Volume: 16, Issue:22

    Topics: Apoptosis; Caspase 3; Caspase 9; Cytarabine; DNA Damage; Drug Synergism; Humans; Leukemia, Myeloid, Acute; Male; Structure-Activity Relationship; Tumor Cells, Cultured; Valproic Acid

2010
A bioluminescent microbial biosensor for in vitro pretreatment assessment of cytarabine efficacy in leukemia.
    Clinical chemistry, 2010, Volume: 56, Issue:12

    Topics: Antimetabolites, Antineoplastic; Biosensing Techniques; Bone Marrow Cells; Cell Line, Tumor; Cytarabine; Cytidine Deaminase; Deoxycytidine Kinase; Drug Resistance, Neoplasm; Escherichia coli; Humans; Intracellular Space; Leukemia, Myeloid, Acute; Luminescent Measurements; Mutation; Nucleoside Deaminases; Phosphorylation

2010
Characteristics and outcome of patients with acute myeloid leukemia refractory to 1 cycle of high-dose cytarabine-based induction chemotherapy.
    Blood, 2010, Dec-23, Volume: 116, Issue:26

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Resistance, Neoplasm; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Survival Rate; Treatment Outcome; Young Adult

2010
Early lymphocyte recovery after intensive timed sequential chemotherapy for acute myelogenous leukemia: peripheral oligoclonal expansion of regulatory T cells.
    Blood, 2011, Jan-13, Volume: 117, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cell Separation; Cytarabine; Cytosine; Daunorubicin; Etoposide; Female; Flavonoids; Flow Cytometry; Gene Expression Profiling; Humans; Immunophenotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Piperidines; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocyte Subsets; T-Lymphocytes, Regulatory; Vidarabine; Young Adult

2011
Improved outcome of patients with low- and intermediate-risk cytogenetics acute myeloid leukemia (AML) in first relapse with gemtuzumab and cytarabine versus cytarabine: results of a retrospective comparative study.
    Cancer, 2011, Mar-01, Volume: 117, Issue:5

    Topics: Adult; Aged; Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Cytogenetic Analysis; Follow-Up Studies; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Middle Aged; Neoplasm Staging; Recurrence; Retrospective Studies; Risk; Salvage Therapy; Treatment Outcome; Young Adult

2011
Chemotherapy: Lo and behold, a role for lomustine in acute myeloid leukemia?
    Nature reviews. Clinical oncology, 2010, Volume: 7, Issue:11

    Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Cytarabine; Humans; Idarubicin; Leukemia, Myeloid, Acute; Lomustine; Nitrosourea Compounds; Treatment Outcome

2010
Acute myelogenous leukemia patients are at low risk for invasive fungal infections after high-dose cytarabine consolidations and thus do not require prophylaxis.
    Acta haematologica, 2010, Volume: 124, Issue:4

    Topics: Adult; Antifungal Agents; Antimetabolites, Antineoplastic; Cytarabine; Dose-Response Relationship, Drug; Female; Fluconazole; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mycoses; Neutropenia; Racial Groups; Reproducibility of Results; Risk Assessment

2010
Salvaging AML with CLAG: novel option, or more of the same?
    Leukemia research, 2011, Volume: 35, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cytarabine; Etoposide; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Neoplasm Recurrence, Local; Remission Induction; Salvage Therapy; Survival Rate; Treatment Outcome

2011
Salvage chemotherapy regimens for acute myeloid leukemia: Is one better? Efficacy comparison between CLAG and MEC regimens.
    Leukemia research, 2011, Volume: 35, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cytarabine; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Neoplasm Recurrence, Local; Remission Induction; Retrospective Studies; Salvage Therapy; Survival Rate; Treatment Outcome; Young Adult

2011
APR-246 exhibits anti-leukemic activity and synergism with conventional chemotherapeutic drugs in acute myeloid leukemia cells.
    European journal of haematology, 2011, Volume: 86, Issue:3

    Topics: Antineoplastic Agents; Aza Compounds; Base Sequence; bcl-2-Associated X Protein; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Daunorubicin; DNA Primers; Drug Resistance, Neoplasm; Drug Synergism; Female; Gene Expression; Genes, p53; Humans; Karyotyping; Leukemia, Myeloid, Acute; Male; Mutation; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured; Tumor Suppressor Protein p14ARF; Vidarabine

2011
Outpatient management of acute myeloid leukemia after intensive consolidation chemotherapy is feasible and reduces hospital treatment costs.
    Onkologie, 2010, Volume: 33, Issue:12

    Topics: Adult; Aged; Ambulatory Care; Anemia, Aplastic; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Blood Transfusion; Cytarabine; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Feasibility Studies; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neutropenia; Opportunistic Infections; Patient Discharge; Patient Readmission; Retrospective Studies; Young Adult

2010
New agents in post-remission therapy.
    Best practice & research. Clinical haematology, 2010, Volume: 23, Issue:4

    Topics: Adult; Age Factors; Aged; Antimetabolites, Antineoplastic; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Stem Cell Transplantation; Transplantation, Homologous

2010
Complete remission and early death after intensive chemotherapy in patients aged 60 years or older with acute myeloid leukaemia: a web-based application for prediction of outcomes.
    Lancet (London, England), 2010, Dec-11, Volume: 376, Issue:9757

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Germany; Humans; Internet; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Multivariate Analysis; Predictive Value of Tests; Prognosis; Regression Analysis; Remission Induction; Risk Assessment; Risk Factors; Surveys and Questionnaires; Time Factors

2010
The topoisomerase II inhibitor voreloxin causes cell cycle arrest and apoptosis in myeloid leukemia cells and acts in synergy with cytarabine.
    Haematologica, 2011, Volume: 96, Issue:3

    Topics: Apoptosis; Cell Culture Techniques; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cytarabine; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Drug Synergism; Female; Gene Deletion; Genes, p53; Humans; Lethal Dose 50; Leukemia, Myeloid, Acute; Male; Middle Aged; Myeloid Cells; Naphthyridines; Thiazoles; Topoisomerase II Inhibitors

2011
The insulin-like growth factor-1 receptor kinase inhibitor, NVP-ADW742, suppresses survival and resistance to chemotherapy in acute myeloid leukemia cells.
    Oncology research, 2010, Volume: 19, Issue:1

    Topics: Apoptosis; Cytarabine; Drug Resistance, Neoplasm; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Receptor, IGF Type 1; Signal Transduction

2010
Aminopeptidase inhibition by the novel agent CHR-2797 (tosedostat) for the therapy of acute myeloid leukemia.
    Leukemia research, 2011, Volume: 35, Issue:5

    Topics: Adult; Aminopeptidases; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Culture Techniques; Cytarabine; Drug Evaluation, Preclinical; Enzyme Inhibitors; Female; Glycine; Humans; Hydroxamic Acids; Leukemia, Myeloid, Acute; Male; Middle Aged; Tumor Cells, Cultured; Young Adult

2011
Low dose of homoharringtonine and cytarabine combined with granulocyte colony-stimulating factor priming on the outcome of relapsed or refractory acute myeloid leukemia.
    Journal of cancer research and clinical oncology, 2011, Volume: 137, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Harringtonines; Homoharringtonine; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Receptors, CXCR4; Recurrence

2011
Acquired protein C deficiency in a child with acute myelogenous leukemia, splenic, renal, and intestinal infarction.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2011, Volume: 22, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Cholecystectomy; Cytarabine; Etoposide; Fibrin Fibrinogen Degradation Products; Fibrinogen; Gallbladder; Heparin, Low-Molecular-Weight; Humans; Idarubicin; Infarction; Kidney; Lebanon; Leukemia, Myeloid, Acute; Male; Protein C; Protein C Deficiency; Remission Induction; Splenectomy; Splenic Infarction; Thrombosis; Tretinoin

2011
The cyclin-dependent kinase inhibitor SNS-032 has single agent activity in AML cells and is highly synergistic with cytarabine.
    Leukemia, 2011, Volume: 25, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Apoptosis; Cell Cycle; Cells, Cultured; Cyclin-Dependent Kinases; Cytarabine; Drug Synergism; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Oxazoles; Phosphorylation; Thiazoles

2011
[Analysis of outocome of pirarubicin-based combination chemotherapy regimen in the treatment of newly diagnosed acute myeloid leukemia-a prospective, open, randomized and multicenter clinical trial].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2010, Volume: 31, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Prospective Studies

2010
Images in clinical medicine. Palmar-plantar rash with cytarabine therapy.
    The New England journal of medicine, 2011, Jan-20, Volume: 364, Issue:3

    Topics: Antimetabolites, Antineoplastic; Cytarabine; Erythema; Foot; Foot Dermatoses; Hand; Hand Dermatoses; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

2011
C-KIT mutation cooperates with full-length AML1-ETO to induce acute myeloid leukemia in mice.
    Proceedings of the National Academy of Sciences of the United States of America, 2011, Feb-08, Volume: 108, Issue:6

    Topics: Animals; Antimetabolites, Antineoplastic; Cell Transformation, Neoplastic; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Core Binding Factor Alpha 2 Subunit; Cytarabine; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mice; Mice, Transgenic; Mutation; NIH 3T3 Cells; Oncogene Proteins, Fusion; Protein Structure, Tertiary; Proto-Oncogene Proteins c-kit; RUNX1 Translocation Partner 1 Protein; Translocation, Genetic

2011
Blood consult: acute myeloid leukemia and the t(8;21)(q22;22).
    Blood, 2011, Mar-10, Volume: 117, Issue:10

    Topics: Amino Acid Sequence; Antineoplastic Combined Chemotherapy Protocols; Base Sequence; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Cytarabine; Daunorubicin; Humans; Immunophenotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation, Missense; Polymerase Chain Reaction; Proto-Oncogene Proteins c-kit

2011
Fludarabine and cytarabine in patients with acute myeloid leukemia refractory to two different courses of front-line chemotherapy.
    Leukemia research, 2011, Volume: 35, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Cytarabine; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Idarubicin; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Remission Induction; Survival Rate; Treatment Outcome; Vidarabine; Young Adult

2011
Escalation of daunorubicin and addition of etoposide in the ADE regimen in acute myeloid leukemia patients aged 60 years and older: Cancer and Leukemia Group B Study 9720.
    Leukemia, 2011, Volume: 25, Issue:5

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Survival Rate; Treatment Outcome

2011
Inhibition of histone deacetylases 1 and 6 enhances cytarabine-induced apoptosis in pediatric acute myeloid leukemia cells.
    PloS one, 2011, Feb-16, Volume: 6, Issue:2

    Topics: Age of Onset; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Child; Cytarabine; Drug Synergism; Gene Knockdown Techniques; Histone Deacetylase 1; Histone Deacetylase 6; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Leukemia, Myeloid, Acute; RNA, Small Interfering; Up-Regulation

2011
Analysis of efficacy and cost-effectiveness of high-dose arabinoside versus daunorubicin chemotherapy in older adult patients with acute myeloid leukemia by cytogenetic risk profile: retrospective review from China.
    International journal of hematology, 2011, Volume: 93, Issue:4

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Cost-Benefit Analysis; Cytarabine; Cytogenetic Analysis; Daunorubicin; Female; Health Care Costs; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

2011
Minimally differentiated acute myeloid leukemia (FAB AML-M0): prognostic factors and treatment effects on survival--a retrospective study of 42 adult cases.
    Leukemia research, 2011, Volume: 35, Issue:8

    Topics: Adult; Aged; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Cell Differentiation; Cytarabine; Female; Follow-Up Studies; Humans; Immunophenotyping; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Retrospective Studies; Survival Rate; Treatment Outcome; Young Adult

2011
Administration schedule of daunorubicin for elderly patients with acute myelogenous leukemia: a single-institute experience.
    Japanese journal of clinical oncology, 2011, Volume: 41, Issue:6

    Topics: Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Remission Induction; Retrospective Studies; Treatment Outcome

2011
[The efficacy and safety of HAA regimen as induction chemotherapy in 150 newly diagnosed acute myeloid leukemia].
    Zhonghua nei ke za zhi, 2011, Volume: 50, Issue:1

    Topics: Aclarubicin; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; Harringtonines; Homoharringtonine; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Survival Rate; Treatment Outcome; Young Adult

2011
Siblings presenting with progressive congenital aleukemic leukemia cutis.
    Pediatric blood & cancer, 2011, Volume: 57, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Dexamethasone; Etoposide; Female; Humans; Infant, Newborn; Leukemia, Myeloid, Acute; Male; Siblings; Skin Neoplasms; Thioguanine

2011
[FLAG regimen in the treatment of refractory and relapsed acute myeloid leukemia].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2011, Volume: 32, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Vidarabine

2011
Most 70- to 79-year-old patients with acute myeloid leukemia do benefit from intensive treatment.
    Blood, 2011, Mar-24, Volume: 117, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Comorbidity; Critical Care; Cytarabine; Decision Making; Humans; Leukemia, Myeloid, Acute; Risk Assessment; Survival Analysis; Sweden; Treatment Outcome; Validation Studies as Topic

2011
Identification of predictive markers of cytarabine response in AML by integrative analysis of gene-expression profiles with multiple phenotypes.
    Pharmacogenomics, 2011, Volume: 12, Issue:3

    Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Child, Preschool; Cytarabine; Drug Resistance, Neoplasm; Female; Gene Expression Profiling; Humans; Leukemia, Myeloid, Acute; Male; Metabolic Networks and Pathways; Phenotype; Prognosis; Treatment Outcome; Young Adult

2011
Inhibition of eIF4E with ribavirin cooperates with common chemotherapies in primary acute myeloid leukemia specimens.
    Leukemia, 2011, Volume: 25, Issue:7

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Binding, Competitive; Clinical Trials, Phase II as Topic; Cytarabine; Drug Synergism; Eukaryotic Initiation Factor-4E; Humans; Idarubicin; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Middle Aged; Niacinamide; Phenylurea Compounds; Pyridines; Ribavirin; RNA Caps; Sorafenib; Tumor Cells, Cultured; Tumor Stem Cell Assay

2011
Clofarabine and high-dose cytosine arabinoside in the treatment of refractory or relapsed acute myeloid leukaemia.
    Annals of hematology, 2011, Volume: 90, Issue:11

    Topics: Adenine Nucleotides; Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Remission Induction; Treatment Outcome; Young Adult

2011
What's up with down syndrome and leukemia-A lot!
    Pediatric blood & cancer, 2011, Jul-15, Volume: 57, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Cytarabine; Disease-Free Survival; Down Syndrome; Doxorubicin; Female; Humans; Infant; Infant, Newborn; Japan; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Survival Rate; Vincristine

2011
A prediction model for complete remission upon reinduction for patients with acute myeloid leukemia after failure of anthracycline and cytarabine standard chemotherapy.
    Annals of hematology, 2011, Volume: 90, Issue:11

    Topics: Adult; Anthracyclines; Antimetabolites, Antineoplastic; Area Under Curve; Chromosome Aberrations; Cytarabine; Disease-Free Survival; Female; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Models, Theoretical; Remission Induction; Retrospective Studies; Treatment Failure; Treatment Outcome

2011
Activity of the multikinase inhibitor sorafenib in combination with cytarabine in acute myeloid leukemia.
    Journal of the National Cancer Institute, 2011, Jun-08, Volume: 103, Issue:11

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; ATP-Binding Cassette Transporters; Benzenesulfonates; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromatography, High Pressure Liquid; Confounding Factors, Epidemiologic; Cytarabine; Disease Models, Animal; Drug Administration Schedule; Gene Expression Regulation, Neoplastic; Humans; Interleukin Receptor Common gamma Subunit; Leukemia, Myeloid, Acute; Mice; Mice, Inbred NOD; Mice, SCID; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Multidrug Resistance-Associated Proteins; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Signal Transduction; Sorafenib; Tandem Mass Spectrometry; Time Factors; Transplantation, Heterologous; Treatment Outcome

2011
Homoharringtonine as a backbone drug for the treatment of newly diagnosed pediatric acute myeloid leukemia: a report from a single institution in China.
    International journal of hematology, 2011, Volume: 93, Issue:5

    Topics: Adolescent; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; China; Clinical Chemistry Tests; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Administration Schedule; Female; Harringtonines; Hematologic Tests; Hepatitis B; Homoharringtonine; Humans; Infant; Leukemia, Myeloid, Acute; Liver Failure; Male; Pancreatitis; Remission Induction; Secondary Prevention

2011
Smoking adversely affects survival in acute myeloid leukemia patients.
    International journal of cancer, 2012, Mar-15, Volume: 130, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Karyotype; Leukemia, Myeloid, Acute; Male; Middle Aged; Multivariate Analysis; Prognosis; Retrospective Studies; Smoking; Survival Rate; Treatment Outcome; Young Adult

2012
Utility of myeloperoxidase stain in the differential diagnosis of leukemia cutis vs. hystiocitoid Sweet syndrome.
    Dermatology online journal, 2011, Apr-15, Volume: 17, Issue:4

    Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cytarabine; Diagnosis, Differential; Humans; Idarubicin; Leukemia, Myeloid, Acute; Leukemic Infiltration; Male; Peroxidase; Skin; Skin Neoplasms; Staining and Labeling; Sweet Syndrome; Treatment Outcome

2011
Treatment of acute myeloid leukemia in children: experience from a tertiary care hematology centre in India.
    Indian journal of pediatrics, 2011, Volume: 78, Issue:10

    Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Child, Preschool; Cytarabine; Disease-Free Survival; Female; Humans; India; Infant; Leukemia, Myeloid, Acute; Male; Remission Induction; Retrospective Studies; Stem Cell Transplantation

2011
An inexpensive way to treat elderly patients with high-risk MDS or AML.
    Leukemia research, 2011, Volume: 35, Issue:8

    Topics: Anemia, Refractory, with Excess of Blasts; Anticonvulsants; Antimetabolites, Antineoplastic; Cytarabine; Humans; Leukemia, Myeloid, Acute; Neoplasm Recurrence, Local; Remission Induction; Treatment Outcome; Valproic Acid

2011
Cytarabine dose for acute myeloid leukemia.
    The New England journal of medicine, 2011, 06-02, Volume: 364, Issue:22

    Topics: Aged; Antimetabolites, Antineoplastic; Cytarabine; Humans; Leukemia, Myeloid, Acute; Middle Aged; Monosomy; Regression Analysis; Survival Analysis; Treatment Outcome

2011
Cytarabine dose for acute myeloid leukemia.
    The New England journal of medicine, 2011, 06-02, Volume: 364, Issue:22

    Topics: Antimetabolites, Antineoplastic; Cytarabine; Drug Administration Schedule; fms-Like Tyrosine Kinase 3; Genes, Duplicate; Humans; Leukemia, Myeloid, Acute; Remission Induction

2011
Cytarabine dose for acute myeloid leukemia.
    The New England journal of medicine, 2011, 06-02, Volume: 364, Issue:22

    Topics: Antimetabolites, Antineoplastic; Cytarabine; Humans; Leukemia, Myeloid, Acute; Remission Induction

2011
Infections in relapsed or refractory acute myeloid leukemia patients given clofarabine+cytarabine.
    Leukemia research, 2011, Volume: 35, Issue:9

    Topics: Adenine Nucleotides; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cytarabine; Drug Resistance, Neoplasm; Humans; Infections; Leukemia, Myeloid, Acute; Recurrence; Treatment Failure

2011
Targeting PIM kinase activity significantly augments the efficacy of cytarabine.
    British journal of haematology, 2012, Volume: 156, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cytarabine; Drug Synergism; Humans; Imidazoles; Leukemia, Myeloid, Acute; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-pim-1; Pyridazines

2012
p53 independent epigenetic-differentiation treatment in xenotransplant models of acute myeloid leukemia.
    Leukemia, 2011, Volume: 25, Issue:11

    Topics: Animals; Antineoplastic Agents; Apoptosis; Azacitidine; Blotting, Western; Cell Differentiation; Cytarabine; Decitabine; DNA Damage; Electrophoresis, Polyacrylamide Gel; Epigenesis, Genetic; Genes, p53; Humans; Leukemia, Myeloid, Acute; Mice; Phosphorylation; Transplantation, Heterologous

2011
Poor-risk cytogenetics may be associated with inferior outcome after fludarabine, cytarabine, and amsacrine reduced intensity conditioning in patients with high-risk acute myeloid leukemia.
    Leukemia & lymphoma, 2011, Volume: 52, Issue:10

    Topics: Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Cytogenetics; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Retrospective Studies; Risk; Transplantation Conditioning; Treatment Outcome; Vidarabine

2011
Genetic variants in cytosolic 5'-nucleotidase II are associated with its expression and cytarabine sensitivity in HapMap cell lines and in patients with acute myeloid leukemia.
    The Journal of pharmacology and experimental therapeutics, 2011, Volume: 339, Issue:1

    Topics: 5'-Nucleotidase; Antimetabolites, Antineoplastic; Base Sequence; Blotting, Western; Cell Line; Cell Line, Tumor; Child; Cytarabine; Cytosol; DNA; Electrophoretic Mobility Shift Assay; Exons; Genetic Variation; Humans; Leukemia, Myeloid, Acute; Luciferases; Methylation; Molecular Sequence Data; Polymorphism, Single Nucleotide; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription Factors

2011
Institutional experience with clofarabine and cytarabine in relapsed pediatric acute myeloid leukemia.
    Journal of pediatric hematology/oncology, 2012, Volume: 34, Issue:1

    Topics: Adenine Nucleotides; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Child; Child, Preschool; Clofarabine; Cytarabine; Female; Hematopoietic Stem Cell Transplantation; Humans; Infant; Leukemia, Myeloid, Acute; Male; Recurrence; Retrospective Studies; Transplantation, Homologous

2012
A scoring system to predict the risk of death during induction with anthracycline plus cytarabine-based chemotherapy in patients with de novo acute myeloid leukemia.
    Cancer, 2012, Jan-15, Volume: 118, Issue:2

    Topics: Adolescent; Adult; Aged; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Risk Assessment; Risk Factors

2012
High-dose cytarabine induction is well tolerated and active in patients with de novo acute myeloid leukemia older than 60 years.
    Cancer, 2012, Jan-15, Volume: 118, Issue:2

    Topics: Aged; Aged, 80 and over; Comorbidity; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Survival Analysis

2012
Use of cytarabine and idarubicin in a newly diagnosed AML patient with a severe wound.
    Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis, 2011, Volume: 45, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Pancytopenia; Pyoderma Gangrenosum; Wound Healing

2011
Applicability of a "Pick a Winner" trial design to acute myeloid leukemia.
    Blood, 2011, Sep-01, Volume: 118, Issue:9

    Topics: Adenine Nucleotides; Aged; Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Arsenic Trioxide; Arsenicals; Clinical Trials, Phase III as Topic; Clofarabine; Cost-Benefit Analysis; Cytarabine; Cytosine; Drug Discovery; Early Termination of Clinical Trials; Follow-Up Studies; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Middle Aged; Multicenter Studies as Topic; Oxides; Patient Selection; Quality-Adjusted Life Years; Quinolones; Randomized Controlled Trials as Topic; Research Design; Sample Size; Software Design; Treatment Outcome; United Kingdom

2011
Cytoreduction with gemtuzumab ozogamicin and cytarabine prior to allogeneic stem cell transplant for relapsed/refractory acute myeloid leukemia.
    Leukemia & lymphoma, 2012, Volume: 53, Issue:10

    Topics: Adult; Aged; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Female; Gemtuzumab; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome

2012
Treatment strategies in patients with core-binding factor acute myeloid leukemia.
    Current oncology reports, 2011, Volume: 13, Issue:5

    Topics: Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Core Binding Factors; Cytarabine; Daunorubicin; Disease-Free Survival; Gemtuzumab; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Vidarabine

2011
Beau's lines.
    The Journal of the Association of Physicians of India, 2011, Volume: 59

    Topics: Antineoplastic Agents; Child; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Nail Diseases; Nails; Treatment Outcome

2011
Therapy-related leukemia cutis with histopathologic changes resembling xanthogranuloma.
    Journal of the American Academy of Dermatology, 2011, Volume: 65, Issue:2

    Topics: Adult; Biopsy, Needle; Cytarabine; Diagnosis, Differential; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Granuloma; Humans; Immunohistochemistry; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukemic Infiltration; Lymphoma, T-Cell; Risk Assessment; Xanthomatosis

2011
AAML03P1, a pilot study of the safety of gemtuzumab ozogamicin in combination with chemotherapy for newly diagnosed childhood acute myeloid leukemia: a report from the Children's Oncology Group.
    Cancer, 2012, Feb-01, Volume: 118, Issue:3

    Topics: Adolescent; Adult; Aminoglycosides; Amsacrine; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Etoposide; Female; Gemtuzumab; Humans; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Male; Neoplasm Staging; Pilot Projects; Prognosis; Survival Rate; Young Adult

2012
Prompt and definitive diagnosis of acute invasive Aspergillus rhinosinusitis in a patient with acute myeloid leukaemia using in situ hybridization: a case report.
    Mycoses, 2012, Volume: 55, Issue:2

    Topics: Aged; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Aspergillosis; Aspergillus; Cytarabine; Humans; Idarubicin; In Situ Hybridization; Itraconazole; Leukemia, Myeloid, Acute; Male; Mycological Typing Techniques; Rhinitis; Sinusitis

2012
Leukocytosis and circulating blasts in older adults with newly diagnosed acute myeloid leukemia: are they valuable factors for therapeutic decision-making?
    Clinical lymphoma, myeloma & leukemia, 2011, Volume: 11, Issue:4

    Topics: Age Factors; Aged; Aged, 80 and over; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Comorbidity; Cytarabine; Cytogenetic Analysis; Female; Humans; Leukemia, Myeloid, Acute; Leukocytes; Leukocytosis; Middle Aged; Prognosis; Retrospective Studies; Treatment Outcome

2011
Patterns of molecular response to and relapse after combination of sorafenib, idarubicin, and cytarabine in patients with FLT3 mutant acute myeloid leukemia.
    Clinical lymphoma, myeloma & leukemia, 2011, Volume: 11, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Cytarabine; Female; fms-Like Tyrosine Kinase 3; Follow-Up Studies; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Niacinamide; Phenylurea Compounds; Pyridines; Recurrence; Remission Induction; Sorafenib; Survival Rate

2011
Reversal of leukostasis-related pulmonary distress syndrome after leukapheresis and low-dose chemotherapy in acute myeloid leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Sep-10, Volume: 29, Issue:26

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Humans; Leukapheresis; Leukemia, Myeloid, Acute; Leukocytosis; Male; Respiratory Distress Syndrome

2011
Risk factors for early death after high-dose cytosine arabinoside (HiDAC)-based chemotherapy for adult AML.
    Leukemia, 2012, Volume: 26, Issue:2

    Topics: Adult; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid, Acute; Middle Aged; Proportional Hazards Models; Risk Factors

2012
Efficacy and safety of CHG regimen (low-dose cytarabine, homoharringtonine with G-CSF priming) as induction chemotherapy for elderly patients with high-risk MDS or AML transformed from MDS.
    Journal of cancer research and clinical oncology, 2011, Volume: 137, Issue:10

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Harringtonines; Homoharringtonine; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Risk

2011
Integrative nucleophosmin mutation-associated microRNA and gene expression pattern analysis identifies novel microRNA - target gene interactions in acute myeloid leukemia.
    Haematologica, 2011, Volume: 96, Issue:12

    Topics: Adult; Antimetabolites, Antineoplastic; Cell Line, Tumor; Cohort Studies; Cytarabine; Female; Gene Expression Regulation, Leukemic; Humans; Leukemia, Myeloid, Acute; Male; MicroRNAs; Middle Aged; Mutation; Neoplasm Proteins; Nuclear Proteins; Nucleophosmin; RNA, Neoplasm

2011
Protection of acute myeloid leukaemia cells from apoptosis induced by front-line chemotherapeutics is mediated by haem oxygenase-1.
    Oncotarget, 2011, Volume: 2, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Female; Heme Oxygenase-1; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Reactive Oxygen Species

2011
Is obesity a prognostic factor for acute myeloid leukemia outcome?
    Annals of hematology, 2012, Volume: 91, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Body Mass Index; Clinical Trials, Phase I as Topic; Cytarabine; Databases, Factual; Female; Humans; Idarubicin; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Obesity; Retrospective Studies; Treatment Outcome; Young Adult

2012
WT1 overexpression at diagnosis may predict favorable outcome in patients with de novo non-M3 acute myeloid leukemia.
    Leukemia & lymphoma, 2011, Volume: 52, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cytarabine; fms-Like Tyrosine Kinase 3; Gene Expression; Humans; Leukemia, Myeloid, Acute; Middle Aged; Mutation; Neoplasm Proteins; Nuclear Proteins; Nucleophosmin; Predictive Value of Tests; Prognosis; Retrospective Studies; Treatment Outcome; WT1 Proteins; Young Adult

2011
Second induction with high-dose cytarabine and mitoxantrone: different impact on pediatric AML patients with t(8;21) and with inv(16).
    Blood, 2011, Nov-17, Volume: 118, Issue:20

    Topics: Adolescent; Antimetabolites, Antineoplastic; Antineoplastic Agents; Child; Chromosome Inversion; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Core Binding Factors; Cytarabine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Humans; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Predictive Value of Tests; Recurrence; Translocation, Genetic; Treatment Outcome

2011
Unexpected pancytopenia following treatment of acute lymphoblastic leukemia.
    American journal of hematology, 2012, Volume: 87, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Chromosomes, Human, Pair 6; Chromosomes, Human, Pair 9; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Daunorubicin; Erythropoiesis; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Maintenance Chemotherapy; Mercaptopurine; Methotrexate; Middle Aged; Neoplasms, Second Primary; Oncogene Proteins, Fusion; Pancytopenia; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Translocation, Genetic; Vincristine

2012
Eccrine hidradenitis sine neutrophils: a toxic response to chemotherapy.
    Journal of cutaneous pathology, 2011, Volume: 38, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Eccrine Glands; Female; Hidradenitis; Humans; Leukemia, Myeloid, Acute; Middle Aged; Neutropenia; Neutrophils; Staphylococcal Skin Infections; Staphylococcus epidermidis

2011
Favorable outcome in infants with AML after intensive first- and second-line treatment: an AML-BFM study group report.
    Leukemia, 2012, Volume: 26, Issue:4

    Topics: Anthracyclines; Child; Child, Preschool; Cytarabine; Female; Hematopoietic Stem Cell Transplantation; Histone-Lysine N-Methyltransferase; Humans; Infant; Leukemia, Myeloid, Acute; Male; Multivariate Analysis; Myeloid-Lymphoid Leukemia Protein; Salvage Therapy; Treatment Outcome

2012
Necrotic intramuscular chloroma with infection: magnetic resonance imaging features.
    Japanese journal of radiology, 2011, Volume: 29, Issue:10

    Topics: Anti-Bacterial Agents; Antimetabolites, Antineoplastic; Child; Contrast Media; Cytarabine; Diagnosis, Differential; Diffusion Magnetic Resonance Imaging; Gentamicins; Humans; Image Enhancement; Klebsiella Infections; Klebsiella pneumoniae; Leg; Leukemia, Myeloid, Acute; Magnetic Resonance Imaging; Male; Meropenem; Muscle Neoplasms; Necrosis; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Sarcoma, Myeloid; Teicoplanin; Thienamycins; Treatment Outcome

2011
FLAGIDA-lite is an effective regimen for patients between 70 and 80 years with acute myeloid leukemia or refractory anemia with excess blasts-2 and is feasible as outpatient treatment.
    American journal of hematology, 2012, Volume: 87, Issue:1

    Topics: Aged; Aged, 80 and over; Ambulatory Care; Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Prognosis; Treatment Outcome; Vidarabine

2012
Prognostic significance of alterations in IDH enzyme isoforms in patients with AML treated with high-dose cytarabine and idarubicin.
    Cancer, 2012, May-15, Volume: 118, Issue:10

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Idarubicin; Isocitrate Dehydrogenase; Leukemia, Myeloid, Acute; Middle Aged; Mutation; Nucleophosmin; Polymorphism, Single Nucleotide; Prognosis

2012
Salvage therapy with endostatin, low-dose homoharringtonine, and cytarabine in combination with granulocyte-colony stimulating factor for elderly patients with primary refractory acute myeloid leukemia.
    American journal of hematology, 2012, Volume: 87, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Endostatins; Female; Granulocyte Colony-Stimulating Factor; Harringtonines; Homoharringtonine; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Prognosis; Salvage Therapy; Treatment Outcome

2012
Acute isolated transmural neutropenic gastritis.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jan-01, Volume: 30, Issue:1

    Topics: Acute Disease; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Carbazoles; Cytarabine; Daunorubicin; Factor VII Deficiency; Female; Furans; Gastritis; Granulocyte Colony-Stimulating Factor; Humans; Incidental Findings; Leukemia, Myeloid, Acute; Middle Aged; Neutropenia; Recurrence; Tomography, X-Ray Computed; Treatment Outcome

2012
Pharmacogenomics of cytarabine in childhood leukemia.
    Pharmacogenomics, 2011, Volume: 12, Issue:12

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Biomarkers, Pharmacological; Child; Child, Preschool; Cytarabine; Deoxycytidine Kinase; Drug Resistance, Neoplasm; Equilibrative Nucleoside Transporter 1; Gene Expression Regulation, Leukemic; Genetic Variation; Humans; Infant; Leukemia, Myeloid, Acute; Signal Transduction

2011
Diffuse osteosclerosis-associated acute myeloid leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jan-01, Volume: 30, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Flow Cytometry; Hematopoietic Stem Cell Transplantation; Humans; Immunohistochemistry; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Magnetic Resonance Imaging; Middle Aged; Osteosclerosis; Remission Induction; Treatment Outcome

2012
Evaluation of prognostic factors in AML. Preface.
    Best practice & research. Clinical haematology, 2011, Volume: 24, Issue:4

    Topics: Aged; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; CCAAT-Enhancer-Binding Proteins; Cytarabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; Europe; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Middle Aged; Mutation; Prognosis; Survival Analysis; United States

2011
Does therapy-related AML have a poor prognosis, independent of the cytogenetic/molecular determinants?
    Best practice & research. Clinical haematology, 2011, Volume: 24, Issue:4

    Topics: Adenine; Anthracyclines; Antineoplastic Agents; Biomarkers, Tumor; Cytarabine; Cytogenetics; Female; Germany; Humans; Leukemia, Myeloid, Acute; Middle Aged; Myelodysplastic Syndromes; Naphthalimides; Naphthyridines; Organophosphonates; Prognosis; Remission Induction; Retrospective Studies; Survival Rate; Thiazoles

2011
Minimal residual disease monitoring based on FLT3 internal tandem duplication in adult acute myeloid leukemia.
    Leukemia research, 2012, Volume: 36, Issue:3

    Topics: Adult; Aged; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cytarabine; Feasibility Studies; Female; fms-Like Tyrosine Kinase 3; Gene Duplication; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasm, Residual; Nuclear Proteins; Nucleophosmin; Prognosis; Real-Time Polymerase Chain Reaction; Remission Induction; Retrospective Studies; Risk Factors; Sensitivity and Specificity; Tandem Repeat Sequences; WT1 Proteins

2012
De novo polycythaemia vera arising 5 years following acute myeloid leukemia remission: suggestion of a chemotherapy resistant JAK2 clone.
    British journal of haematology, 2012, Volume: 157, Issue:2

    Topics: Amino Acid Substitution; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Resistance, Neoplasm; Female; Humans; Janus Kinase 2; Leukemia, Myeloid, Acute; Middle Aged; Mutation, Missense; Polycythemia Vera

2012
Mitoxantrone and etoposide with or without intermediate dose cytarabine for the treatment of primary induction failure or relapsed acute myeloid leukemia.
    Leukemia research, 2012, Volume: 36, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Cytogenetics; Etoposide; Female; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Recurrence; Retrospective Studies; Salvage Therapy; Treatment Outcome; Young Adult

2012
Renaissance of autologous stem cell transplantation for AML?
    The Lancet. Oncology, 2012, Volume: 13, Issue:2

    Topics: Cytarabine; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male

2012
Characteristics of translocation (16;16)(p13;q22) acute myeloid leukemia.
    American journal of hematology, 2012, Volume: 87, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chromosome Inversion; Chromosomes, Human, Pair 16; Cytarabine; Disease-Free Survival; Female; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Male; Middle Aged; Oncogene Proteins, Fusion; Remission Induction; Retrospective Studies; Translocation, Genetic; Vidarabine

2012
Posterior reversible encephalopathy syndrome (PRES) during induction chemotherapy for acute myeloblastic leukemia (AML).
    Annals of hematology, 2012, Volume: 91, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Middle Aged; Posterior Leukoencephalopathy Syndrome; Young Adult

2012
Cutaneous myeloid sarcoma presenting as grey pigmented macules.
    Acta dermato-venereologica, 2012, Volume: 92, Issue:6

    Topics: Aclarubicin; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 7; Cytarabine; Humans; Leukemia, Myeloid, Acute; Male; Sarcoma, Myeloid; Skin; Skin Neoplasms; Skin Pigmentation; Translocation, Genetic; Treatment Outcome

2012
Integrated genomic analyses identify WEE1 as a critical mediator of cell fate and a novel therapeutic target in acute myeloid leukemia.
    Leukemia, 2012, Volume: 26, Issue:6

    Topics: Antimetabolites, Antineoplastic; Biomarkers, Tumor; Blotting, Western; Cell Cycle Proteins; Cytarabine; Gene Expression Profiling; Genome, Human; Genomics; Humans; Leukemia, Myeloid, Acute; Nuclear Proteins; Oligonucleotide Array Sequence Analysis; Protein-Tyrosine Kinases; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; S Phase; Tumor Cells, Cultured

2012
Phospho-specific flow: fixating on the target.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Mar-15, Volume: 18, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Ribosomal Protein S6; Sirolimus; TOR Serine-Threonine Kinases

2012
Cytidine deaminase genetic variants influence RNA expression and cytarabine cytotoxicity in acute myeloid leukemia.
    Pharmacogenomics, 2012, Volume: 13, Issue:3

    Topics: 3' Untranslated Regions; 5' Untranslated Regions; Adolescent; Adult; Aged; Base Sequence; Case-Control Studies; Cell Line, Tumor; Cytarabine; Cytidine Deaminase; Drug Resistance, Neoplasm; Female; Gene Expression; Haplotypes; Humans; Introns; Leukemia, Myeloid, Acute; Male; Middle Aged; Molecular Sequence Data; Polymorphism, Single Nucleotide; RNA, Messenger; U937 Cells; Young Adult

2012
Nine years interval between first and second bone marrow transplantations and subsequent long-term survival--a case of acute myeloid leukemia with MLL-AF6 fusion gene.
    Annals of hematology, 2012, Volume: 91, Issue:9

    Topics: Adult; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Clone Cells; Combined Modality Therapy; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Lymphocyte Transfusion; Male; Mercaptopurine; Myeloid-Lymphoid Leukemia Protein; Neoplastic Stem Cells; Oncogene Proteins, Fusion; Prednisolone; Recurrence; Remission Induction; Reoperation; Time Factors; Transplantation, Homologous; Vincristine

2012
Are low-intensity induction strategies better for older patients with acute myeloid leukemia?
    Leukemia research, 2012, Volume: 36, Issue:4

    Topics: Aged; Aged, 80 and over; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Cytarabine; Daunorubicin; Etoposide; Female; Gemtuzumab; Humans; Induction Chemotherapy; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Oxides; Quinolones; Remission Induction; Retrospective Studies; Treatment Outcome

2012
Concurrent acute myeloid leukemia and T lymphoblastic lymphoma in a patient with rearranged PDGFRB genes.
    Diagnostic pathology, 2012, Feb-22, Volume: 7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Daunorubicin; Fatal Outcome; Graft vs Host Disease; Humans; Leukemia, Myeloid, Acute; Male; Neoplasms, Multiple Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptor, Platelet-Derived Growth Factor beta; Stem Cell Transplantation

2012
FLAG-liposomal doxorubicin (Myocet) regimen for refractory or relapsed acute leukemia pediatric patients.
    Journal of pediatric hematology/oncology, 2012, Volume: 34, Issue:3

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Doxorubicin; Drug Resistance, Neoplasm; Female; Granulocyte Colony-Stimulating Factor; Humans; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Male; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Salvage Therapy; Survival Rate; Vidarabine

2012
Myeloperoxidase expression in acute myeloid leukemia helps identifying patients to benefit from transplant.
    Yonsei medical journal, 2012, Volume: 53, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cytarabine; Disease-Free Survival; Female; Flow Cytometry; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Immunophenotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Peroxidase; Retrospective Studies; Young Adult

2012
Targeting Aurora A kinase activity with the investigational agent alisertib increases the efficacy of cytarabine through a FOXO-dependent mechanism.
    International journal of cancer, 2012, Dec-01, Volume: 131, Issue:11

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Aurora Kinase A; Aurora Kinases; Azepines; Bcl-2-Like Protein 11; Cell Cycle; Cell Line, Tumor; Cell Survival; Cyclin-Dependent Kinase Inhibitor p27; Cytarabine; Drug Synergism; Female; Forkhead Box Protein O3; Forkhead Transcription Factors; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Membrane Proteins; Mice; Mice, SCID; Molecular Targeted Therapy; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Pyrimidines; Xenograft Model Antitumor Assays

2012
Valproic acid synergistically enhances the cytotoxicity of clofarabine in pediatric acute myeloid leukemia cells.
    Pediatric blood & cancer, 2012, Dec-15, Volume: 59, Issue:7

    Topics: Adenine Nucleotides; Adolescent; Antineoplastic Agents; Apoptosis; Arabinonucleosides; Cell Line, Tumor; Child; Child, Preschool; Clofarabine; Cytarabine; DNA Damage; Drug Screening Assays, Antitumor; Drug Synergism; Female; Histone Deacetylase Inhibitors; Humans; Infant; Leukemia, Myeloid, Acute; Male; Tumor Cells, Cultured; Valproic Acid

2012
Low-dose cytarabine plus aclarubicin for patients with previously untreated acute myeloid leukemia or high-risk myelodysplastic syndrome ineligible for standard-dose cytarabine plus anthracycline.
    Anticancer research, 2012, Volume: 32, Issue:4

    Topics: Aclarubicin; Aged; Aged, 80 and over; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes

2012
Therapy for older patients with acute myeloblastic leukemia: a problem in search of a solution.
    Leukemia & lymphoma, 2012, Volume: 53, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Valproic Acid

2012
Flow cytometry-based assessment of mitoxantrone efflux from leukemic blasts varies with response to induction chemotherapy in acute myeloid leukemia.
    Cytometry. Part B, Clinical cytometry, 2012, Volume: 82, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cyclosporine; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Female; Flow Cytometry; Humans; Induction Chemotherapy; Karyotype; Leukemia, Myeloid, Acute; Lymphoid Progenitor Cells; Male; Middle Aged; Mitoxantrone; Neoplasm Proteins; Statistics, Nonparametric; Young Adult

2012
Bilateral ear swelling and erythema after chemotherapy: a case of ara-C ears.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jun-01, Volume: 30, Issue:16

    Topics: Cytarabine; Ear Diseases; Ear, External; Edema; Female; Humans; Leukemia, Myeloid, Acute; Middle Aged

2012
[GATA1-mutation associated leukemia in children with trisomy 21 mosaic].
    Klinische Padiatrie, 2012, Volume: 224, Issue:3

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Down Syndrome; Female; Follow-Up Studies; GATA1 Transcription Factor; Hematopoietic Stem Cell Transplantation; Humans; Infant; Infant, Newborn; Leukemia, Megakaryoblastic, Acute; Leukemia, Myeloid, Acute; Male; Mosaicism; Mutation; Myelopoiesis; Myeloproliferative Disorders

2012
Going beyond 7 + 3 regimens in the treatment of adult acute myeloid leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Jul-10, Volume: 30, Issue:20

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Humans; Leukemia, Myeloid, Acute; Middle Aged

2012
Lytic bone disease as the presenting feature of Philadelphia-positive monosomy 7 myelodysplasia progressing to acute myeloid leukaemia.
    Gene, 2012, Jun-15, Volume: 501, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Bone Diseases; Chromosome Deletion; Chromosomes, Human, Pair 19; Chromosomes, Human, Pair 7; Chromosomes, Human, Pair 9; Cytarabine; Humans; Idarubicin; Imatinib Mesylate; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Pain; Philadelphia Chromosome; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Radiography; Vidarabine

2012
Flow cytometric detection of liposomal cytarabine in cerebrospinal fluid of patients treated with intrathecal chemotherapy.
    Cytometry. Part B, Clinical cytometry, 2012, Volume: 82, Issue:5

    Topics: Antimetabolites, Antineoplastic; Cytarabine; Flow Cytometry; Humans; Injections, Spinal; Leukemia, Myeloid, Acute; Liposomes; Lymphoma, Non-Hodgkin

2012
Clinical and proteomic characterization of acute myeloid leukemia with mutated RAS.
    Cancer, 2012, Nov-15, Volume: 118, Issue:22

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; Genes, ras; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Neoplasm Proteins; Proteomics; ras Proteins; Remission Induction; Retrospective Studies; Signal Transduction; Young Adult

2012
Combination of cytarabine and topotecan in patients treated for acute myeloid leukemia with persistent disease after frontline induction.
    Leukemia & lymphoma, 2012, Volume: 53, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Topotecan

2012
Profiling of drug-metabolizing enzymes/transporters in CD33+ acute myeloid leukemia patients treated with Gemtuzumab-Ozogamicin and Fludarabine, Cytarabine and Idarubicin.
    The pharmacogenomics journal, 2013, Volume: 13, Issue:4

    Topics: Aminoglycosides; Antibodies, Monoclonal, Humanized; Cytarabine; Enzymes; Female; Gemtuzumab; Genetic Heterogeneity; Genotype; Humans; Idarubicin; Inactivation, Metabolic; Leukemia, Myeloid, Acute; Male; Neoplasm Recurrence, Local; Sialic Acid Binding Ig-like Lectin 3; Treatment Outcome; Vidarabine

2013
[Percutaneous coronary intervention in a patient with acute myeloid leukemia].
    Deutsche medizinische Wochenschrift (1946), 2012, Volume: 137, Issue:21

    Topics: Angioplasty, Balloon, Coronary; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bone Marrow; Coronary Angiography; Cytarabine; Female; Heart Failure; Humans; Leukemia, Myeloid, Acute; Lymph Nodes; Middle Aged; Mitoxantrone; Mitral Valve Insufficiency; Myocardial Infarction; Myocardial Ischemia; Platelet Aggregation Inhibitors; Platelet Transfusion; Remission Induction; Stents; Thrombocytopenia

2012
High TOP2B/TOP2A expression ratio at diagnosis correlates with favourable outcome for standard chemotherapy in acute myeloid leukaemia.
    British journal of cancer, 2012, Jun-26, Volume: 107, Issue:1

    Topics: Anthracyclines; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Marrow; Cell Line, Tumor; Cytarabine; Disease-Free Survival; DNA Topoisomerases, Type II; DNA-Binding Proteins; Drug Resistance, Neoplasm; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Poly-ADP-Ribose Binding Proteins; Prognosis; Ribonucleoside Diphosphate Reductase; Treatment Outcome

2012
Bone marrow stromal cells modulate mouse ENT1 activity and protect leukemia cells from cytarabine induced apoptosis.
    PloS one, 2012, Volume: 7, Issue:5

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Bone Marrow Cells; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytarabine; Equilibrative Nucleoside Transporter 1; Humans; Leukemia, Myeloid, Acute; Mice; Stromal Cells; Tumor Cells, Cultured

2012
Identification of drugs including a dopamine receptor antagonist that selectively target cancer stem cells.
    Cell, 2012, Jun-08, Volume: 149, Issue:6

    Topics: Animals; Antineoplastic Agents; Cytarabine; Dopamine Antagonists; Drug Screening Assays, Antitumor; Humans; Leukemia, Myeloid, Acute; Mefloquine; Mice; Neoplastic Stem Cells; Pluripotent Stem Cells; Pyrans; Thioridazine

2012
Refractory disseminated fusariosis by Fusarium verticillioides in a patient with acute myeloid leukaemia relapsed after allogeneic hematopoietic stem cell transplantation: a case report and literature review.
    Revista iberoamericana de micologia, 2013, Jan-03, Volume: 30, Issue:1

    Topics: Adult; Amphotericin B; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Drug Resistance, Multiple, Fungal; Etoposide; Fatal Outcome; Female; Fusariosis; Fusarium; Humans; Immunocompromised Host; Itraconazole; Leukemia, Myeloid, Acute; Mitoxantrone; Neutropenia; Peripheral Blood Stem Cell Transplantation; Postoperative Complications; Premedication; Pyrimidines; Recurrence; Salvage Therapy; Transplantation, Homologous; Triazoles; Voriconazole

2013
Copy number variations in normal karyotype acute myeloid leukaemia and their association with treatment response.
    Basic & clinical pharmacology & toxicology, 2012, Volume: 111, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; DNA Copy Number Variations; Drug Resistance, Neoplasm; Female; Genome-Wide Association Study; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Oligonucleotide Array Sequence Analysis; Prognosis; Republic of Korea; Survival Analysis; Young Adult

2012
Be quick, but don't hurry.
    Blood, 2012, Jun-07, Volume: 119, Issue:23

    Topics: Antimetabolites, Antineoplastic; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male

2012
Drug shortages delay cancer clinical trials.
    Journal of the National Cancer Institute, 2012, Jun-20, Volume: 104, Issue:12

    Topics: Adenine Nucleotides; Aged; Antineoplastic Agents; Arabinonucleosides; Child; Clinical Trials as Topic; Clofarabine; Cytarabine; Daunorubicin; Drug Approval; Drug Industry; Drugs, Generic; Europe; Humans; Leukemia, Myeloid, Acute; National Cancer Institute (U.S.); Patient Selection; Survival Analysis; Time Factors; United States; United States Food and Drug Administration

2012
Older age is associated with similar quality of life and physical function compared to younger age during intensive chemotherapy for acute myeloid leukemia.
    Leukemia research, 2012, Volume: 36, Issue:10

    Topics: Activities of Daily Living; Adult; Age Factors; Aged; Aged, 80 and over; Aging; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Longitudinal Studies; Male; Middle Aged; Prospective Studies; Quality of Life; Treatment Outcome; Young Adult

2012
Overexpression of the novel member of the BCL2 gene family, BCL2L12, is associated with the disease outcome in patients with acute myeloid leukemia.
    Clinical biochemistry, 2012, Volume: 45, Issue:16-17

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Case-Control Studies; Cytarabine; Daunorubicin; Etoposide; Gene Expression; Gene Expression Regulation, Neoplastic; Hepatomegaly; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Middle Aged; Multivariate Analysis; Muscle Proteins; Neoplasm Recurrence, Local; Prognosis; Proportional Hazards Models; Proto-Oncogene Proteins c-bcl-2; Splenomegaly; Treatment Outcome; Up-Regulation; Young Adult

2012
[Lethal pulmonary hemorrhage caused by Stenotrophomonas maltophilia pneumonia in a patient with acute myeloid leukemia].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 2012, Volume: 86, Issue:3

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Fatal Outcome; Gram-Negative Bacterial Infections; Hemorrhage; Humans; Leukemia, Myeloid, Acute; Lung Diseases; Male; Middle Aged; Pneumonia, Bacterial; Stenotrophomonas maltophilia

2012
Acute myeloid leukaemia with abnormal eosinophil precursors without inversion 16.
    British journal of haematology, 2012, Volume: 158, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Cytarabine; Eosinophilia; Eosinophils; Granulocyte Precursor Cells; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Oncogene Proteins, Fusion

2012
Probable cytarabine-induced acral erythema: report of 2 pediatric cases.
    Journal of pediatric hematology/oncology, 2013, Volume: 35, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Cytarabine; Etoposide; Female; Hand-Foot Syndrome; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis

2013
[Role of high-dose cytarabine as consolidation therapy for cytogenetically intermediate AML: a single center analysis].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2012, Volume: 33, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Treatment Outcome; Young Adult

2012
Fludarabine, cytarabine, granulocyte-colony stimulating factor and amsacrine: an effective salvage therapy option for acute myeloid leukemia at first relapse.
    Leukemia & lymphoma, 2013, Volume: 54, Issue:2

    Topics: Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Recurrence; Salvage Therapy; Transplantation, Homologous; Treatment Outcome; Vidarabine; Young Adult

2013
Fractionated doses of gemtuzumab ozogamicin combined with 3 + 7 induction chemotherapy as salvage treatment for young patients with acute myeloid leukemia in first relapse.
    Annals of hematology, 2012, Volume: 91, Issue:12

    Topics: Adult; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Follow-Up Studies; Gemtuzumab; Hematopoietic Stem Cell Transplantation; Hepatic Veno-Occlusive Disease; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Retrospective Studies; Salvage Therapy; Severity of Illness Index; Survival Analysis

2012
[Genetic prognostic factors in childhood acute myeloid leukemia].
    Klinische Padiatrie, 2012, Volume: 224, Issue:6

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Chromosome Aberrations; Chromosome Deletion; Chromosome Disorders; Chromosomes, Human, Pair 7; Cytarabine; DNA Mutational Analysis; Etoposide; Female; fms-Like Tyrosine Kinase 3; Genes, Wilms Tumor; Genetic Markers; Humans; Idarubicin; Infant; Kaplan-Meier Estimate; Karyotyping; Leukemia, Myeloid, Acute; Male; Myelodysplastic Syndromes; Nuclear Proteins; Nucleophosmin; Prognosis; Survival Rate; Translocation, Genetic

2012
Favorable outcome in a patient with vulvar mucormycosis during acute myeloid leukemia induction with medical management alone.
    Hematology/oncology and stem cell therapy, 2012, Volume: 5, Issue:2

    Topics: Adult; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Mucormycosis; Vulvar Diseases

2012
Successful importation of cytarabine into the United States during a critical national drug shortage.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2012, Aug-15, Volume: 69, Issue:16

    Topics: Antimetabolites, Antineoplastic; Cytarabine; Drug Approval; Drug Costs; Drug Industry; Humans; Informed Consent; International Cooperation; Leukemia, Myeloid, Acute; Minnesota; Organizational Case Studies; Pharmacy Service, Hospital; Risk Assessment; Switzerland; United States; United States Food and Drug Administration

2012
Effects of selective checkpoint kinase 1 inhibition on cytarabine cytotoxicity in acute myelogenous leukemia cells in vitro.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Oct-01, Volume: 18, Issue:19

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Checkpoint Kinase 1; Cytarabine; Humans; Leukemia, Myeloid, Acute; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Pyrazoles; Pyrimidines

2012
Association of polymorphisms of cytosine arabinoside-metabolizing enzyme gene with therapeutic efficacy for acute myeloid leukemia.
    Chinese medical journal, 2012, Volume: 125, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cytarabine; Cytidine Deaminase; Deoxycytidine Kinase; Female; Gene Frequency; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Polymorphism, Single Nucleotide; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Treatment Outcome; Young Adult

2012
Fatal palmar-plantar erythrodysesthesia after clofarabine and cytarabine chemotherapy.
    Acta haematologica, 2012, Volume: 128, Issue:3

    Topics: Adenine Nucleotides; Antineoplastic Agents; Arabinonucleosides; Clofarabine; Cytarabine; Fatal Outcome; Hand-Foot Syndrome; Humans; Leukemia, Myeloid, Acute

2012
[Efficacy of granisetron for preventing chemotherapy-induced nausea and vomiting in patients with acute myelogenous leukemia treated with a combination of anthracycline and cytarabine].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2012, Volume: 39, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Anthracyclines; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Constipation; Cytarabine; Female; Granisetron; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Nausea; Retrospective Studies; Vomiting; Young Adult

2012
Disseminated Langerhans cell histiocytosis associated with acute myeloid leukaemia: complete remission with daunorubicin and cytarabine.
    Annals of hematology, 2013, Volume: 92, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Histiocytosis, Langerhans-Cell; Humans; Leukemia, Myeloid, Acute; Lymph Nodes; Male; Palatine Tonsil; Remission Induction

2013
Overexpression of MN1 confers resistance to chemotherapy, accelerates leukemia onset, and suppresses p53 and Bim induction.
    PloS one, 2012, Volume: 7, Issue:8

    Topics: Animals; Antineoplastic Agents; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Cell Line, Tumor; Cytarabine; Disease Models, Animal; Doxorubicin; Gene Expression Regulation, Leukemic; Histones; Leukemia, Myeloid, Acute; Membrane Proteins; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Oncogene Proteins; Prognosis; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Trans-Activators; Tumor Suppressor Protein p53; Tumor Suppressor Proteins

2012
Influence of chemotherapy on the lipid peroxidation and antioxidant status in patients with acute myeloid leukemia.
    Acta medica Iranica, 2012, Volume: 50, Issue:7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Cytarabine; Daunorubicin; Female; Glutathione Peroxidase; Humans; Leukemia, Myeloid, Acute; Lipid Peroxidation; Male; Malondialdehyde; Middle Aged; Superoxide Dismutase

2012
[Effects of IAT and MAT chemotherapeutic regimens in patients with refractory or relapsed acute myeloid leukemia].
    Zhongguo shi yan xue ye xue za zhi, 2012, Volume: 20, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Retrospective Studies; Vidarabine; Young Adult

2012
Combined interaction of multi-locus genetic polymorphisms in cytarabine arabinoside metabolic pathway on clinical outcomes in adult acute myeloid leukaemia (AML) patients.
    European journal of cancer (Oxford, England : 1990), 2013, Volume: 49, Issue:2

    Topics: Adolescent; Adult; Aged; Case-Control Studies; Cytarabine; Female; Genetic Loci; Genotype; Humans; Leukemia, Myeloid, Acute; Male; Metabolic Networks and Pathways; Middle Aged; Multilocus Sequence Typing; Polymorphism, Single Nucleotide; Treatment Outcome; Young Adult

2013
[Comparative evaluation of CHAG and CAG priming regimen for treatment of refractory and relapsed acute myeloid leukemia].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2012, Volume: 33, Issue:6

    Topics: Aclarubicin; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Glutethimide; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Treatment Outcome; Young Adult

2012
[Retrospective analysis of treatment outcomes in 70 patients with t(8;21) acute myeloid leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2012, Volume: 53, Issue:7

    Topics: Adolescent; Antimetabolites, Antineoplastic; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Cytarabine; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Maintenance Chemotherapy; Male; Remission Induction; Retrospective Studies; Survival Rate; Translocation, Genetic; Transplantation, Homologous; Treatment Outcome

2012
Gemtuzumab ozogamicin: time to resurrect?
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Nov-10, Volume: 30, Issue:32

    Topics: Age Factors; Aged; Aminoglycosides; Anthracyclines; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Drug Approval; Gemtuzumab; Humans; Immunotoxins; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Middle Aged; Treatment Outcome; United States; United States Food and Drug Administration

2012
High response rate for treatment with gemtuzumab ozogamicin and cytarabine in elderly patients with acute myeloid leukemia and favorable and intermediate-I cytogenetic risk.
    Clinical lymphoma, myeloma & leukemia, 2012, Volume: 12, Issue:6

    Topics: Aged; Aged, 80 and over; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Cytogenetics; Disease-Free Survival; Female; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Retrospective Studies; Risk Factors

2012
KIT D816 mutation associates with adverse outcomes in core binding factor acute myeloid leukemia, especially in the subgroup with RUNX1/RUNX1T1 rearrangement.
    Annals of hematology, 2013, Volume: 92, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chromosome Inversion; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Combined Modality Therapy; Core Binding Factor Alpha 2 Subunit; Core Binding Factors; Cytarabine; Disease-Free Survival; Exons; Female; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Kaplan-Meier Estimate; Korea; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Proteins; Point Mutation; Prognosis; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-kit; RUNX1 Translocation Partner 1 Protein; Transcription Factors; Translocation, Genetic; Treatment Outcome; Young Adult

2013
An unusual initial manifestation of acute leukemia.
    The American journal of medicine, 2012, Volume: 125, Issue:12

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Bone Marrow; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Paraneoplastic Syndromes; Skin Diseases, Papulosquamous

2012
Complete remission following chemotherapy with low-dose cytosine arabinoside and macrophage colony-stimulating factor/granulocyte colony-stimulating factor in a patient with relapsed acute myeloid leukemia after stem cell transplantation.
    Internal medicine (Tokyo, Japan), 2012, Volume: 51, Issue:20

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Macrophage Colony-Stimulating Factor; Male; Recurrence; Remission Induction; Stem Cell Transplantation

2012
Cytarabine toxicity of the corneal endothelium.
    Annals of hematology, 2013, Volume: 92, Issue:4

    Topics: Adult; Antimetabolites, Antineoplastic; Cytarabine; Endothelium, Corneal; Eye Diseases; Humans; Leukemia, Myeloid, Acute; Male; Vision Disorders

2013
Lenalidomide-mediated enhanced translation of C/EBPα-p30 protein up-regulates expression of the antileukemic microRNA-181a in acute myeloid leukemia.
    Blood, 2013, Jan-03, Volume: 121, Issue:1

    Topics: Adult; Animals; Antimetabolites, Antineoplastic; CCAAT-Enhancer-Binding Proteins; Cell Line, Tumor; Cytarabine; Frameshift Mutation; Gene Expression Regulation, Leukemic; Humans; Immunologic Factors; K562 Cells; Lenalidomide; Leukemia, Myeloid, Acute; Mice; Mice, Inbred NOD; Mice, SCID; MicroRNAs; Neoplasm Proteins; Point Mutation; Promoter Regions, Genetic; Protein Isoforms; Protein Structure, Tertiary; Recombinant Fusion Proteins; RNA, Neoplasm; Thalidomide; Up-Regulation; Xenograft Model Antitumor Assays

2013
Ethyl 2-amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate (CXL017): a novel scaffold that resensitizes multidrug resistant leukemia cells to chemotherapy.
    ACS chemical biology, 2013, Feb-15, Volume: 8, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Benzopyrans; Cell Survival; Cytarabine; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Structure-Activity Relationship; Tumor Cells, Cultured

2013
An extreme example of focal bone marrow involvement in acute myeloid leukemia.
    American journal of hematology, 2013, Volume: 88, Issue:4

    Topics: Antineoplastic Agents; Bone Marrow; Cytarabine; Daunorubicin; Humans; Ilium; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Sternum

2013
Expression of CD25 independently predicts early treatment failure of acute myeloid leukaemia (AML).
    British journal of haematology, 2013, Volume: 160, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Female; fms-Like Tyrosine Kinase 3; Gene Duplication; Gene Expression Regulation, Leukemic; Hematopoietic Stem Cell Transplantation; Humans; Interleukin-2 Receptor alpha Subunit; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Neoplasm Proteins; Neoplastic Stem Cells; Retrospective Studies; Tandem Repeat Sequences; Treatment Failure

2013
What is better for older patients with acute myeloid leukemia?
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Feb-20, Volume: 31, Issue:6

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Choice Behavior; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Palliative Care; Patient Participation

2013
When azanucleoside treatment can be curative: nonintensive bridging strategy before allografting in older patients with myelodysplastic syndrome/acute myeloid leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Feb-20, Volume: 31, Issue:6

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Choice Behavior; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Palliative Care; Patient Participation

2013
A historical perspective on the development of the cytarabine (7days) and daunorubicin (3days) treatment regimen for acute myelogenous leukemia: 2013 the 40th anniversary of 7+3.
    Blood cells, molecules & diseases, 2013, Volume: 50, Issue:2

    Topics: Adolescent; Adult; Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Cancer Care Facilities; Case Management; Child; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Daunorubicin; Dogs; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Forecasting; France; Haplorhini; Hematology; History, 20th Century; History, 21st Century; Humans; Leukemia, Myeloid, Acute; Male; Medical Oncology; Mercaptopurine; Middle Aged; National Institutes of Health (U.S.); Rats; Remission Induction; United States

2013
Acute megakaryoblastic leukemia in a patient with xeroderma pigmentosum: discussion of pathophysiological, prognostic, and toxicological aspects.
    Acta haematologica, 2013, Volume: 129, Issue:2

    Topics: Adult; Aneuploidy; Cytarabine; Daunorubicin; DNA Repair; Fatal Outcome; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Leukemia, Megakaryoblastic, Acute; Leukemia, Myeloid, Acute; Male; Neoadjuvant Therapy; Recurrence; Remission Induction; Transplantation, Homologous; Vidarabine; Xeroderma Pigmentosum

2013
Neutropenia-associated outcomes in adults with acute myeloid leukemia receiving cytarabine consolidation chemotherapy with or without granulocyte colony-stimulating factor.
    Pharmacotherapy, 2012, Volume: 32, Issue:12

    Topics: Academic Medical Centers; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Cytarabine; Dose-Response Relationship, Drug; Female; Fever; Filgrastim; Granulocyte Colony-Stimulating Factor; Hospitalization; Humans; Length of Stay; Leukemia, Myeloid, Acute; Male; Middle Aged; Neutropenia; Polyethylene Glycols; Recombinant Proteins; Retrospective Studies; Survival Rate; Time Factors; Treatment Outcome; Young Adult

2012
Outcome of poor response paediatric AML using early SCT.
    European journal of haematology, 2013, Volume: 90, Issue:3

    Topics: Adolescent; Child; Child, Preschool; Cytarabine; Disease-Free Survival; Early Medical Intervention; Etoposide; Female; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Histocompatibility Testing; Humans; Idarubicin; Induction Chemotherapy; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Myeloablative Agonists; Thioguanine; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome

2013
Cell of origin determines clinically relevant subtypes of MLL-rearranged AML.
    Leukemia, 2013, Volume: 27, Issue:4

    Topics: Adult; Animals; Antineoplastic Agents; Cytarabine; Gene Expression Profiling; Histone-Lysine N-Methyltransferase; Humans; Leukemia, Myeloid, Acute; Mice; Mice, Inbred C57BL; Myeloid-Lymphoid Leukemia Protein

2013
Multiplexed mAbs: a new strategy in preclinical time-domain imaging of acute myeloid leukemia.
    Blood, 2013, Feb-14, Volume: 121, Issue:7

    Topics: Animals; Anthracyclines; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; CD11b Antigen; CD11c Antigen; Cell Line, Tumor; Cytarabine; Fluorescent Dyes; Green Fluorescent Proteins; HL-60 Cells; Humans; Immunophenotyping; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Luminescent Measurements; Mice; Mice, Inbred NOD; Mice, Knockout; Mice, SCID; Optical Imaging; Tretinoin; Valproic Acid; Xenograft Model Antitumor Assays

2013
Small-molecule inhibition of BRD4 as a new potent approach to eliminate leukemic stem- and progenitor cells in acute myeloid leukemia AML.
    Oncotarget, 2012, Volume: 3, Issue:12

    Topics: ADP-ribosyl Cyclase 1; Adult; Aged; Aged, 80 and over; Antigens, CD34; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azepines; Cell Cycle Proteins; Cell Proliferation; Cytarabine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; Female; HL-60 Cells; Humans; Inhibitory Concentration 50; Leukemia, Myeloid, Acute; Male; Membrane Glycoproteins; Middle Aged; Molecular Targeted Therapy; Neoplastic Stem Cells; Nuclear Proteins; RNA, Messenger; Transcription Factors; Triazoles; Tumor Cells, Cultured; U937 Cells; Young Adult

2012
Idarubicin is superior to daunorubicin in remission induction of de novo acute myeloid leukemia patients with high MDR1 expression.
    Pharmacogenomics, 2013, Volume: 14, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Marrow Cells; Cytarabine; Daunorubicin; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Remission Induction; Retrospective Studies; RNA, Messenger

2013
Utility of a clinical risk score to identify high-risk patients with de novo acute myeloid leukaemia in first remission after high-dose cytarabine (HiDAC) based induction chemotherapy.
    British journal of haematology, 2013, Volume: 160, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Cytarabine; Disease-Free Survival; Female; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Risk Factors; Survival Analysis; Treatment Outcome; Young Adult

2013
Increased CDA expression/activity in males contributes to decreased cytidine analog half-life and likely contributes to worse outcomes with 5-azacytidine or decitabine therapy.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2013, Feb-15, Volume: 19, Issue:4

    Topics: Animals; Azacitidine; Cytarabine; Cytidine; Cytidine Deaminase; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Female; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Myeloid, Acute; Male; Mice; Myelodysplastic Syndromes; Polymorphism, Single Nucleotide; Survival Analysis; Treatment Outcome

2013
A case report of acute myeloid leukemia after liver transplantation.
    Acta haematologica, 2013, Volume: 129, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Bone Marrow; Cytarabine; Daunorubicin; Hepatitis B; Humans; Leukemia, Myeloid, Acute; Liver Cirrhosis; Liver Transplantation; Male; Middle Aged; Mitoxantrone; Oxides; Tretinoin

2013
Neutrophilic eccrine hidradenitis induced by cytarabine.
    Acta dermatovenerologica Croatica : ADC, 2012, Volume: 20, Issue:4

    Topics: Antimetabolites, Antineoplastic; Cytarabine; Eccrine Glands; Female; Hidradenitis; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Middle Aged

2012
Combination of guanine arabinoside and Bcl-2 inhibitor YC137 overcomes the cytarabine resistance in HL-60 leukemia cell line.
    Cancer science, 2013, Volume: 104, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Arabinonucleosides; Cytarabine; Drug Resistance, Neoplasm; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Proto-Oncogene Proteins c-bcl-2; Thiazoles

2013
AML cells are differentially sensitive to chemotherapy treatment in a human xenograft model.
    Blood, 2013, Mar-21, Volume: 121, Issue:12

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cytarabine; Doxorubicin; Drug Administration Routes; Drug Resistance, Neoplasm; Hematopoiesis; Humans; Leukemia, Myeloid, Acute; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, SCID; Mice, Transgenic; Treatment Outcome; Xenograft Model Antitumor Assays

2013
The HSP90 inhibitor NVP-AUY922-AG inhibits the PI3K and IKK signalling pathways and synergizes with cytarabine in acute myeloid leukaemia cells.
    British journal of haematology, 2013, Volume: 161, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Annexin A5; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caspase 3; Cytarabine; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Female; HSP90 Heat-Shock Proteins; Humans; I-kappa B Kinase; Isoxazoles; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Proteins; Phosphatidylinositol 3-Kinases; Resorcinols; Signal Transduction; Tumor Cells, Cultured; Young Adult

2013
Time from diagnosis to intensive chemotherapy initiation does not adversely impact the outcome of patients with acute myeloid leukemia.
    Blood, 2013, Apr-04, Volume: 121, Issue:14

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Humans; Idarubicin; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Multivariate Analysis; Prognosis; Retrospective Studies; Risk Factors; Time-to-Treatment; Treatment Outcome; Young Adult

2013
CHAG priming regimen containing of cytarabine, aclacinomycin homoharringtonine and G-CSF for relapsed refractory acute myelogenous leukemia: a modified combination chemotherapeutic combination.
    Leukemia & lymphoma, 2013, Volume: 54, Issue:10

    Topics: Aclarubicin; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Granulocyte Colony-Stimulating Factor; Harringtonines; Homoharringtonine; Humans; Leukemia, Myeloid, Acute; Treatment Outcome

2013
Enhancing the efficacy of Ara-C through conjugation with PAMAM dendrimer and linear PEG: a comparative study.
    Biomacromolecules, 2013, Mar-11, Volume: 14, Issue:3

    Topics: Arabinofuranosyluracil; Cell Line, Tumor; Chemical Phenomena; Chromatography, High Pressure Liquid; Cytarabine; Cytidine Deaminase; Dendrimers; Humans; Hydrogen-Ion Concentration; Leukemia, Myeloid, Acute; Magnetic Resonance Spectroscopy; Particle Size; Polyethylene Glycols; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2013
A case of acantholytic dermatosis and leukemia cutis: cause or effect?
    The American Journal of dermatopathology, 2002, Volume: 24, Issue:3

    Topics: Acantholysis; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Humans; Leukemia, Myeloid, Acute; Leukemic Infiltration; Male; Skin; Skin Neoplasms; Treatment Outcome

2002
A case of treatment-related myelodysplastic syndrome and acute myelogenous leukemia following high-dose chemotherapy with autologous stem cell transplantation for non-Hodgkin's lymphoma.
    Journal of Korean medical science, 2002, Volume: 17, Issue:4

    Topics: Adult; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; B-Lymphocytes; Bone Marrow Cells; Carmustine; Chromosome Aberrations; Chromosomes, Human, Pair 11; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Etoposide; Female; Gene Rearrangement; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Myelodysplastic Syndromes; Neoplasms, Second Primary; Pelvis; Pregnancy; Pregnancy Complications, Neoplastic; Transplantation, Autologous

2002
Neutropenic colitis after treatment of acute myelogenous leukemia with idarubicin and cytosine arabinoside.
    Mayo Clinic proceedings, 2002, Volume: 77, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colitis; Cytarabine; Female; Humans; Idarubicin; Incidence; Leukemia, Myeloid, Acute; Male; Middle Aged; Neutropenia; Retrospective Studies; Treatment Outcome

2002
Acute myocardial infarction as the presenting symptom of acute myeloblastic leukemia with extreme hyperleukocytosis.
    American journal of hematology, 2002, Volume: 71, Issue:1

    Topics: Aminoglycosides; Anti-Bacterial Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Confusion; Cytarabine; Etoposide; Fatal Outcome; Female; Gemtuzumab; Humans; Idarubicin; Immunotherapy; Leukapheresis; Leukemia, Myeloid, Acute; Leukocytosis; Middle Aged; Mitoxantrone; Myocardial Infarction; Recurrence; Remission Induction; Salvage Therapy; Sialic Acid Binding Ig-like Lectin 3; Therapeutics; Vidarabine

2002
Acute myelogenous leukemia following treatment with cyclosporin A in a nephrotic patient.
    Internal medicine (Tokyo, Japan), 2002, Volume: 41, Issue:9

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cyclosporine; Cytarabine; Daunorubicin; Humans; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Male; Nephrotic Syndrome; Treatment Outcome

2002
Isolated trisomy of chromosomes 8, 11, 13 and 21 is an adverse prognostic factor in adults with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B 8461.
    International journal of oncology, 2002, Volume: 21, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 13; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Cytarabine; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Survival Rate; Treatment Outcome; Trisomy

2002
Enterocolitis as initial presentation of acute myelogenous leukemia exacerbated by induction chemotherapy with idarubicin-cytosine arabinoside.
    Mayo Clinic proceedings, 2002, Volume: 77, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colitis; Cytarabine; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Middle Aged; Neutropenia

2002
Acute myelogenous leukaemia in older patients at St Bartholomew's Hospital: outcome with mitoxantrone and cytarabine.
    The hematology journal : the official journal of the European Haematology Association, 2002, Volume: 3, Issue:5

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Chromosome Aberrations; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Ploidies; Prognosis; Remission Induction; Survival Analysis; Treatment Outcome

2002
Factors influencing outcome and incidence of long-term complications in children who underwent autologous stem cell transplantation for acute myeloid leukemia in first complete remission.
    Blood, 2003, Feb-15, Volume: 101, Issue:4

    Topics: Adolescent; Amsacrine; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells; Carmustine; Child; Child, Preschool; Cytarabine; Disease-Free Survival; Etoposide; Female; Follow-Up Studies; Hematopoiesis; Hematopoietic Stem Cell Transplantation; Humans; Infant; Leukemia, Myeloid, Acute; Male; Neutrophils; Peripheral Blood Stem Cell Transplantation; Recurrence; Remission Induction; Retrospective Studies; Survival Rate; Transplantation Conditioning; Transplantation, Autologous; Treatment Outcome

2003
High-dose cytosine arabinoside-induced cutaneous reactions.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2002, Volume: 16, Issue:5

    Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Cytarabine; Drug Eruptions; Female; Humans; Incidence; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies

2002
Fulminant tumour lysis syndrome in acute myelogenous leukaemia with inv(16)(p13;q22).
    European journal of haematology, 2002, Volume: 69, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Agents; Chromosome Inversion; Chromosomes, Human, Pair 16; Cytarabine; Daunorubicin; Female; Genetic Predisposition to Disease; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Tumor Lysis Syndrome

2002
[WT1 gene expression in patients with acute myelogenous leukemia or high risk myelodysplastic syndrome successfully treated with the CAG regimen].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2002, Volume: 43, Issue:10

    Topics: Aclarubicin; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Remission Induction; WT1 Proteins

2002
Sustained complete hematologic remission after administration of the tyrosine kinase inhibitor imatinib mesylate in a patient with refractory, secondary AML.
    Blood, 2003, Apr-15, Volume: 101, Issue:8

    Topics: Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Bone Marrow; Cytarabine; Daunorubicin; Disease Progression; Drug Resistance, Neoplasm; Enzyme Inhibitors; Exons; Humans; Imatinib Mesylate; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Proteins; Neoplastic Stem Cells; Piperazines; Proto-Oncogene Proteins c-kit; Pyrimidines; Receptors, Platelet-Derived Growth Factor; Recurrence; Remission Induction; Salvage Therapy

2003
Acute myelogenous leukaemia presenting as a conjunctival lesion and red eye.
    Acta ophthalmologica Scandinavica, 2002, Volume: 80, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Conjunctiva; Conjunctival Neoplasms; Cytarabine; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute

2002
Pilot study of Mylotarg, idarubicin and cytarabine combination regimen in patients with primary resistant or relapsed acute myeloid leukemia.
    Cancer chemotherapy and pharmacology, 2003, Volume: 51, Issue:1

    Topics: Adult; Aged; Aminoglycosides; Anti-Bacterial Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Resistance, Neoplasm; Female; Gemtuzumab; Hepatic Veno-Occlusive Disease; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Pilot Projects; Recurrence

2003
A novel fusion variant of the MORF and CBP genes detected in therapy-related myelodysplastic syndrome with t(10;16)(q22;p13).
    British journal of haematology, 2003, Volume: 120, Issue:2

    Topics: Acetyltransferases; Antineoplastic Combined Chemotherapy Protocols; Carrier Proteins; Chromosomes, Human, Pair 10; Chromosomes, Human, Pair 16; Cytarabine; Female; Gene Rearrangement; Histone Acetyltransferases; Humans; Idarubicin; Leukemia, Myeloid, Acute; Middle Aged; Myelodysplastic Syndromes; Reverse Transcriptase Polymerase Chain Reaction; Saccharomyces cerevisiae Proteins; Sequence Analysis, DNA; Translocation, Genetic

2003
Long-term outcomes of acute myeloid leukemia in adults in Pakistan.
    JPMA. The Journal of the Pakistan Medical Association, 2002, Volume: 52, Issue:10

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Pakistan; Remission Induction; Survival Analysis; Treatment Outcome

2002
[The effect of interferon alone, cytosine arabinoside alone and their combined effect on hematopoietic progenitors of chronic myeloid leukemia in vitro].
    Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, 2002, Volume: 33, Issue:2

    Topics: Adult; Cell Division; Cytarabine; Drug Synergism; Female; Hematopoietic Stem Cells; Humans; Interferons; K562 Cells; Leukemia, Myeloid, Acute; Male; Middle Aged

2002
[Effects of small-dose cytarabine on the course of atheromatosis in over 60 years of age patients with acute myeloblastic leukemia (description of 2 cases)].
    Terapevticheskii arkhiv, 2002, Volume: 74, Issue:12

    Topics: Age Factors; Aged; Antimetabolites, Antineoplastic; Arteriosclerosis; Cell Division; Cytarabine; Female; Humans; Hypertension; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Male; Middle Aged; Time Factors

2002
Fatal Bacillus cereus sepsis following resolving neutropenic enterocolitis during the treatment of acute leukemia.
    American journal of hematology, 2003, Volume: 72, Issue:3

    Topics: Adult; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Bacillaceae Infections; Bacillus cereus; Cytarabine; Enterocolitis; Fatal Outcome; Humans; Idarubicin; Leukemia, Myeloid, Acute; Liver Diseases; Male; Neutropenia; Sepsis

2003
Fludarabine, ARA-C, idarubicin and G-CSF (FLAG-Ida), high dose ARA-C and early stem cell transplant. A feasable and effective therapeutic strategy for de novo AML patients.
    Journal of experimental & clinical cancer research : CR, 2002, Volume: 21, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Patient Selection; Recombinant Proteins; Retrospective Studies; Stem Cell Transplantation; Survival Analysis; Treatment Outcome; Vidarabine

2002
Efficacy of SCH66336, a farnesyl transferase inhibitor, in conjunction with imatinib against BCR-ABL-positive cells.
    Molecular cancer therapeutics, 2003, Volume: 2, Issue:3

    Topics: Alkyl and Aryl Transferases; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzamides; Cell Division; Colony-Forming Units Assay; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Farnesyltranstransferase; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Interleukin-3; Leukemia, Myeloid, Acute; Piperazines; Piperidines; Protein-Tyrosine Kinases; Pyridines; Pyrimidines; Transfection; Treatment Outcome; Tumor Cells, Cultured

2003
Severe hyperglycemia as a complication of big ICE chemotherapy in a patient with acute myeloblastic leukemia.
    Haematologia, 2002, Volume: 32, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Blood Glucose; Cytarabine; Etoposide; Female; Humans; Hyperglycemia; Idarubicin; Insulin; Leukemia, Myeloid, Acute; Recurrence; Time Factors

2002
Sweet's syndrome masquerading as facial cellulitis.
    Cutis, 2003, Volume: 71, Issue:6

    Topics: Antineoplastic Agents; Cellulitis; Cytarabine; Diagnosis, Differential; Face; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Middle Aged; Sweet Syndrome; Treatment Outcome

2003
The comprehensive evaluation on four indices of drug resistance in acute myeloid leukemia.
    Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, 1999, Volume: 19, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; bcl-2-Associated X Protein; Cell Division; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Harringtonines; Humans; Leukemia, Myeloid, Acute; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tumor Stem Cell Assay

1999
A case of leukemia of the appendix presenting as acute appendicitis.
    Acta haematologica, 2003, Volume: 109, Issue:4

    Topics: Aged; Antigens, CD; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Appendectomy; Appendicitis; Appendix; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease Progression; Fatal Outcome; Humans; Idarubicin; Immunophenotyping; Leukemia, Myeloid, Acute; Leukemic Infiltration; Male; Mercaptopurine; Sarcoma, Myeloid

2003
Effects of TNFalpha on the growth and sensitivity to cytosine arabinoside of blast progenitors in acute myelogenous leukemia with special reference to the role of NF-kappaB.
    Leukemia research, 2003, Volume: 27, Issue:11

    Topics: Adult; Aged; Blast Crisis; Cell Division; Cytarabine; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; NF-kappa B; Tumor Necrosis Factor-alpha

2003
[High dose ara-C therapy induced bradycardia in an acute myeloid leukemia patient with inv (16)(p13q22)].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2003, Volume: 44, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bradycardia; Chromosome Inversion; Chromosomes, Human, Pair 16; Cytarabine; Etoposide; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Remission Induction

2003
Interaction between leukemic-cell VLA-4 and stromal fibronectin is a decisive factor for minimal residual disease of acute myelogenous leukemia.
    Nature medicine, 2003, Volume: 9, Issue:9

    Topics: Animals; Antibodies; Antimetabolites, Antineoplastic; Cytarabine; Drug Resistance, Neoplasm; Fibronectins; Humans; Integrin alpha4beta1; Integrin alpha5beta1; Leukemia; Leukemia, Myeloid, Acute; Mice; Mice, SCID; Neoplasm, Residual; Phosphatidylinositol 3-Kinases; Predictive Value of Tests; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Stromal Cells; Survival Rate; Time Factors; Tumor Cells, Cultured

2003
[Chemotherapy with ubenimex corresponding to patient age and organ disorder for 18 cases of acute myelogeneous leukemia in elderly patients--effects, complications and long-term survival].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:8

    Topics: Aclarubicin; Age Factors; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Leucine; Leukemia, Myeloid, Acute; Male; Remission Induction; Survival Rate

2003
[Acute myeloblastic leukemia in adults: evaluation of the AML 06/96 protocol].
    La Tunisie medicale, 2003, Volume: 81, Issue:7

    Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Doxorubicin; Female; Humans; Leukemia, Myeloid, Acute; Lomustine; Male; Middle Aged; Prospective Studies; Recurrence; Remission Induction; Time Factors

2003
Acute myeloid leukemia presenting as non-neutropenic colitis in an infant.
    Journal of pediatric gastroenterology and nutrition, 2003, Volume: 37, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colitis; Colon; Cytarabine; Daunorubicin; Dexamethasone; Etoposide; Female; Gastrointestinal Hemorrhage; Humans; Immunohistochemistry; Infant; Leukemia, Myeloid, Acute; Leukemic Infiltration; Leukocyte Common Antigens; Peroxidase; Sigmoidoscopy; Thioguanine

2003
[Intensive multi-drug chemotherapy for acute myeloid leukemia in a renal allograft recipient].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2003, Volume: 44, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Kidney Transplantation; Leukemia, Myeloid, Acute; Male; Middle Aged; Postoperative Complications

2003
Low dose gemtuzumab ozogamicin for relapsed acute myeloid leukaemia in elderly.
    Haematologica, 2003, Volume: 88, Issue:12

    Topics: Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Etoposide; Gemtuzumab; Humans; Idarubicin; Immunotoxins; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Salvage Therapy; Transplantation, Autologous

2003
[Acute myelogenous leukemia complicated with severe tumor lysis syndrome after a single day of idarubicin/cytarabine chemotherapy].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2003, Volume: 44, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Tumor Lysis Syndrome

2003
Comparison of BAVC to BuCy regimens in autologous stem cell transplantation for adult patients with acute myeloid leukemia.
    Haematologica, 2004, Volume: 89, Issue:1

    Topics: Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Carmustine; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Drug Combinations; Etoposide; Female; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Megakaryoblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Retrospective Studies; Stem Cell Transplantation; Transplantation, Autologous

2004
Biphasic acute myeloid leukemia with near-tetraploidy and immunophenotypic transformation.
    Archives of pathology & laboratory medicine, 2004, Volume: 128, Issue:4

    Topics: Adult; Aneuploidy; Antigens, CD; Antigens, CD7; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; CD56 Antigen; Cell Size; Chromosome Deletion; Chromosomes, Human, Pair 7; Cytarabine; Daunorubicin; DNA, Neoplasm; Fatal Outcome; Humans; Immunophenotyping; Leukemia, Myeloid, Acute; Male; Neoplasm Recurrence, Local; Peripheral Blood Stem Cell Transplantation; Transplantation, Autologous; Transplantation, Homologous

2004
Lack of effect of the human GM-CSF analog E21R on the survival of primary human acute myeloid leukemia cells.
    Blood, 2004, Apr-15, Volume: 103, Issue:8

    Topics: Antimetabolites, Antineoplastic; Binding, Competitive; Cell Death; Cell Division; Cell Survival; Cytarabine; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; In Vitro Techniques; Leukemia, Myeloid, Acute; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor; Recombinant Proteins

2004
Drastic effect of cell density on the cytotoxicity of daunorubicin and cytosine arabinoside.
    Biochemical pharmacology, 2004, May-01, Volume: 67, Issue:9

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Apoptosis; Cell Count; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; HL-60 Cells; Humans; Leukemia, Myeloid, Acute

2004
Core binding factor acute myeloid leukemia. Cancer and Leukemia Group B (CALGB) Study 8461.
    Annals of hematology, 2004, Volume: 83 Suppl 1

    Topics: Adult; Antimetabolites, Antineoplastic; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Core Binding Factor Alpha 2 Subunit; Cytarabine; DNA-Binding Proteins; Humans; Leukemia, Myeloid, Acute; Neoplasms; Proto-Oncogene Proteins; Transcription Factors; Translocation, Genetic

2004
Cholesterol synthesis and import contribute to protective cholesterol increments in acute myeloid leukemia cells.
    Blood, 2004, Sep-15, Volume: 104, Issue:6

    Topics: Biological Transport; Cholesterol, LDL; Coenzyme A Ligases; Cytarabine; Flow Cytometry; Humans; Hydroxymethylglutaryl-CoA Synthase; Leukemia, Myeloid, Acute; Lovastatin; Receptors, LDL; RNA, Messenger; Tumor Cells, Cultured

2004
Gemtuzumab ozogamicin plus cytarabine determines complete remission in acute myeloid leukemia refractory to a double conventional treatment: a case report.
    Haematologica, 2004, Jun-01, Volume: 89, Issue:6 Suppl

    Topics: Aged; Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Gemtuzumab; Humans; Immunotoxins; Leukemia, Myeloid, Acute; Salvage Therapy; Treatment Outcome

2004
A novel effective and safe consolidation for patients over 60 years with acute myeloid leukemia: intermediate dose cytarabine (2 x 1 g/m2 on days 1, 3, and 5).
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Jun-15, Volume: 10, Issue:12 Pt 1

    Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Humans; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Time Factors; Treatment Outcome

2004
Sweet's syndrome associated with sargramostim (granulocyte-macrophage colony stimulating factor) treatment.
    American journal of hematology, 2004, Volume: 76, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy; Cytarabine; Daunorubicin; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisone; Recombinant Proteins; Remission Induction; Skin; Sweet Syndrome

2004
Hepatotoxicity due to a possible interaction between cytosine arabinoside and dipyridamole: a case report.
    European journal of clinical pharmacology, 2004, Volume: 60, Issue:6

    Topics: Antimetabolites, Antineoplastic; Blood Cell Count; Chemical and Drug Induced Liver Injury; Cytarabine; Dipyridamole; Drug Interactions; Fatal Outcome; Humans; Leukemia, Myeloid, Acute; Liver Function Tests; Male; Middle Aged; Multiple Organ Failure; Platelet Aggregation Inhibitors

2004
Isolated recurrence of granulocytic sarcoma manifesting as extra- and intracranial masses--case report.
    Neurologia medico-chirurgica, 2004, Volume: 44, Issue:6

    Topics: Adult; Antineoplastic Agents; Biopsy, Needle; Brain Injuries; Brain Neoplasms; Core Binding Factor Alpha 2 Subunit; Cytarabine; DNA-Binding Proteins; Female; Humans; In Situ Hybridization, Fluorescence; Leukemia, Myeloid, Acute; Magnetic Resonance Imaging; Proto-Oncogene Proteins; RUNX1 Translocation Partner 1 Protein; Sarcoma, Myeloid; Transcription Factors

2004
[Five cases of de novo acute myeloid leukemia with trilineage myelodysplasia (AML/TMDS) achieved CR with the continuous drip infusion of low-dose etoposide and low-dose cytosine arabinoside combined with mitoxantrone (MEtA)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cell Lineage; Cytarabine; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Male; Middle Aged; Mitoxantrone; Myelodysplastic Syndromes; Remission Induction

2004
A new approach to treatment of acute myelogenous leukemia using targeted therapy in combination with standard chemotherapy.
    Leukemia research, 2004, Volume: 28, Issue:11

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Cytokines; Diphtheria Toxin; Humans; Leukemia, Myeloid, Acute; Mice; Mice, Inbred NOD; Mice, SCID; Recombinant Fusion Proteins

2004
Teaching cases from the Royal Marsden and St Mary's Hospitals case 28: a patient with acute leukemia with rare leukemic cells of unusual morphology.
    Leukemia & lymphoma, 2004, Volume: 45, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells; Cytarabine; Daunorubicin; Humans; Immunophenotyping; In Situ Hybridization, Fluorescence; Leukemia, Myeloid, Acute; Lymph Nodes; Male; Middle Aged; Prognosis; Remission Induction; Reverse Transcriptase Polymerase Chain Reaction; Translocation, Genetic

2004
Early deaths and treatment-related mortality in children undergoing therapy for acute myeloid leukemia: analysis of the multicenter clinical trials AML-BFM 93 and AML-BFM 98.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, Nov-01, Volume: 22, Issue:21

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cause of Death; Chi-Square Distribution; Child; Child, Preschool; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Incidence; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Logistic Models; Male; Mitoxantrone; Randomized Controlled Trials as Topic; Retrospective Studies; Risk Factors; Survival Rate

2004
An in vitro study on the mechanisms of coagulation activation in acute myelogenous leukemia (AML): role of tissue factor regulation by cytotoxic drugs and GM-CSF.
    Thrombosis and haemostasis, 2004, Volume: 92, Issue:5

    Topics: Antineoplastic Agents; Blood Cells; Blood Coagulation; Cell Death; Cells, Cultured; Cytarabine; Daunorubicin; Granulocyte Precursor Cells; Granulocyte-Macrophage Colony-Stimulating Factor; HL-60 Cells; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Thromboplastin

2004
Cytarabine-induced neurotoxicity responding to methyl prednisolone.
    American journal of hematology, 2004, Volume: 77, Issue:4

    Topics: Adult; Antimetabolites, Antineoplastic; Cytarabine; Fatal Outcome; Female; Humans; Injections, Intravenous; Leukemia, Myeloid, Acute; Methylprednisolone; Neurotoxicity Syndromes

2004
[Pseudomonas sepsis with ecthyma gangrenosum in an acute myeloid leukemia patient].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2004, Volume: 45, Issue:10

    Topics: Anti-Infective Agents; Antineoplastic Combined Chemotherapy Protocols; Ciprofloxacin; Cytarabine; Ecthyma; Female; gamma-Globulins; Humans; Idarubicin; Immunocompromised Host; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Pseudomonas aeruginosa; Pseudomonas Infections; Scalp; Sepsis; Treatment Outcome

2004
[Infection control in neutropenia induced by high-dose cytarabine chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Laryngeal Mucosa; Leukemia, Myeloid, Acute; Middle Aged; Neutropenia; Retrospective Studies; Risk; Streptococcal Infections

2004
Complex t(8;14;21)(q22;q13;q22), a variant of t(8;21), with t(15;21)(q15;p11) in a patient with acute myelogenous leukemia (M1).
    Cancer genetics and cytogenetics, 2004, Volume: 155, Issue:2

    Topics: Antimetabolites, Antineoplastic; Chromosomes, Human, Pair 14; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Core Binding Factor Alpha 2 Subunit; Cytarabine; Drug Therapy, Combination; Female; Genetic Variation; Humans; Idarubicin; Karyotyping; Leukemia, Myeloid, Acute; Leukocytes, Mononuclear; Middle Aged; Oncogene Proteins, Fusion; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RUNX1 Translocation Partner 1 Protein; Secondary Prevention; Transcription Factors; Translocation, Genetic

2004
A single-center, retrospective study of management and outcome of 45 elderly AML patients, diagnosed in 2001.
    Journal of experimental & clinical cancer research : CR, 2004, Volume: 23, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Recurrence; Remission Induction; Retrospective Studies; Time Factors; Treatment Outcome; Tretinoin

2004
Acute myeloid leukemia in the elderly: etoposide when anthracyclins are contraindicated.
    Leukemia & lymphoma, 2005, Volume: 46, Issue:3

    Topics: Aged; Aged, 80 and over; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Contraindications; Cytarabine; Daunorubicin; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Remission Induction; Retrospective Studies; Survival Analysis

2005
Anti-CD33 monoclonal antibodies enhance the cytotoxic effects of cytosine arabinoside and idarubicin on acute myeloid leukemia cells through similarities in their signaling pathways.
    Experimental hematology, 2005, Volume: 33, Issue:2

    Topics: Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Cell Line, Tumor; Cell Survival; Cytarabine; Humans; Idarubicin; Leukemia, Myeloid, Acute; Sialic Acid Binding Ig-like Lectin 3; Signal Transduction

2005
Small-molecule XIAP inhibitors derepress downstream effector caspases and induce apoptosis of acute myeloid leukemia cells.
    Blood, 2005, May-15, Volume: 105, Issue:10

    Topics: Aniline Compounds; Apoptosis; Caspases; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Phenylurea Compounds; Proteins; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured; X-Linked Inhibitor of Apoptosis Protein

2005
Heat shock protein 90 inhibition sensitizes acute myelogenous leukemia cells to cytarabine.
    Blood, 2005, Jul-01, Volume: 106, Issue:1

    Topics: Antimetabolites, Antineoplastic; Benzoquinones; Checkpoint Kinase 1; Cytarabine; Drug Synergism; HL-60 Cells; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Leukemia, Myeloid, Acute; Protein Kinases; Rifabutin; RNA, Small Interfering; S Phase

2005
Use of MLL/GRAF fusion mRNA for measurement of minimal residual disease during chemotherapy in an infant with acute monoblastic leukemia (AML-M5).
    Genes, chromosomes & cancer, 2005, Volume: 43, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; DNA-Binding Proteins; Etoposide; GTPase-Activating Proteins; Histone-Lysine N-Methyltransferase; Humans; Idarubicin; In Situ Hybridization, Fluorescence; Infant; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Myeloid-Lymphoid Leukemia Protein; Neoplasm, Residual; Oncogene Proteins, Fusion; Proto-Oncogenes; RNA, Messenger; Transcription Factors

2005
Trying to improve clinical outcome in AML: lessons from negative trials.
    Leukemia research, 2005, Volume: 29, Issue:6

    Topics: Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Gemtuzumab; Humans; Idarubicin; Interleukin-11; Leukemia, Myeloid, Acute; Randomized Controlled Trials as Topic; Treatment Outcome

2005
Curing acute myelogenous leukemia: still a major challenge.
    Leukemia research, 2005, Volume: 29, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Leukemia, Myeloid, Acute; Neoplasm, Residual; Risk Factors; Survival Analysis

2005
Activation of the RAS pathway is predictive for a chemosensitive phenotype of acute myelogenous leukemia blasts.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, May-01, Volume: 11, Issue:9

    Topics: Antimetabolites, Antineoplastic; Bone Marrow Cells; Cytarabine; HeLa Cells; Humans; Immunoblotting; Leukemia, Myeloid, Acute; Middle Aged; Mutation; Phenotype; Prognosis; ras Proteins; Signal Transduction; Survival Analysis; Treatment Outcome

2005
GM-CSF and low-dose cytosine arabinoside in high-risk, elderly patients with AML or MDS.
    Oncology (Williston Park, N.Y.), 2005, Volume: 19, Issue:4 Suppl 2

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Neutropenia; Recombinant Proteins; Retrospective Studies; Risk Assessment; Risk Factors

2005
Increase in Ara-C cytotoxicity in the presence of valproate, a histone deacetylase inhibitor, is associated with the concurrent expression of cyclin D1 and p27(Kip 1) in acute myeloblastic leukemia cells.
    Leukemia research, 2005, Volume: 29, Issue:11

    Topics: Butyrates; Cell Cycle; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p27; Cytarabine; Enzyme Inhibitors; Etoposide; Histone Deacetylase Inhibitors; Humans; Leukemia, Myeloid, Acute; Valproic Acid

2005
Determination of caspase-3 activation fails to predict chemosensitivity in primary acute myeloid leukemia blasts.
    BMC cancer, 2005, Jun-11, Volume: 5

    Topics: Adult; Aged; Antineoplastic Agents; Apoptosis; Bone Marrow Cells; Caspase 3; Caspases; Cell Death; Cell Line, Tumor; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Activation; Female; Humans; Kinetics; Leukemia, Myeloid, Acute; Male; Middle Aged; Spectrometry, Fluorescence; Tetrazolium Salts; Thiazoles

2005
Fludarabine and cytarabine as continuous sequential infusion for elderly patients with acute myeloid leukemia.
    Haematologica, 2005, Volume: 90, Issue:6

    Topics: Aged; Aged, 80 and over; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Stem Cell Transplantation; Treatment Outcome; Vidarabine

2005
[Effects of FLAG regimen in treatment of refractory or relapsed acute myeloid leukemia].
    Zhongguo shi yan xue ye xue za zhi, 2005, Volume: 13, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Diarrhea; Drug Resistance, Neoplasm; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Male; Middle Aged; Nausea; Neoplasm Recurrence, Local; Respiratory Tract Infections; Treatment Outcome; Vidarabine

2005
Outcome of patients with acute myelogenous leukemia after second salvage therapy.
    Cancer, 2005, Aug-01, Volume: 104, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents; Combined Modality Therapy; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Remission Induction; Salvage Therapy; Stem Cell Transplantation; Survival Rate; Transplantation, Homologous; Treatment Outcome

2005
Granulocytic sarcoma of the heart: extramedullary relapse of acute myeloblastic leukemia after allogeneic stem cell transplantation successfully treated by chemotherapy alone.
    Leukemia & lymphoma, 2005, Volume: 46, Issue:7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Heart Neoplasms; Humans; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Neoplasm Recurrence, Local; Peripheral Blood Stem Cell Transplantation; Remission Induction; Sarcoma, Myeloid; Transplantation, Homologous

2005
Cytarabine-induced lung injury: case report.
    Anti-cancer drugs, 2005, Volume: 16, Issue:7

    Topics: Aged; Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Cytarabine; Fatal Outcome; Humans; Leukemia, Myeloid, Acute; Male; Prednisolone; Respiratory Distress Syndrome

2005
[Therapeutic effects of chemotherapeutic regimens containing pirarubicin on the treatment of high-risk or refractory and relapsed acute leukemia in adults].
    Zhonghua yi xue za zhi, 2005, May-11, Volume: 85, Issue:17

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Doxorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Vincristine

2005
Molecular basis for G2 arrest induced by 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine and consequences of checkpoint abrogation.
    Cancer research, 2005, Aug-01, Volume: 65, Issue:15

    Topics: Antineoplastic Agents; Apoptosis; CDC2 Protein Kinase; Cell Line, Tumor; Checkpoint Kinase 1; Chromosome Aberrations; Cytarabine; DNA Damage; Drug Interactions; G2 Phase; Hematologic Neoplasms; Humans; Leukemia, Myeloid, Acute; Mitosis; Protein Kinases; Signal Transduction; Staurosporine

2005
Clonogenic growth patterns correlate with chemotherapy response in acute myeloid leukaemia.
    Hematology (Amsterdam, Netherlands), 2005, Volume: 10, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Agents; Cell Survival; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myeloid Progenitor Cells; Neoplastic Stem Cells; Pilot Projects; Predictive Value of Tests; Treatment Outcome; Tumor Cells, Cultured; Tumor Stem Cell Assay

2005
Oncogenic potential of the transcription factor LYL1 in acute myeloblastic leukemia.
    Leukemia, 2005, Volume: 19, Issue:11

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Basic Helix-Loop-Helix Transcription Factors; Bone Marrow; Cell Transformation, Neoplastic; Cytarabine; DNA-Binding Proteins; DNA, Complementary; Drug Resistance, Neoplasm; Electroporation; Gene Expression Profiling; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Neoplasm Proteins; Phenotype; Retroviridae; Reverse Transcriptase Polymerase Chain Reaction; Tretinoin; Tumor Cells, Cultured

2005
Sequential regimen of chemotherapy, reduced-intensity conditioning for allogeneic stem-cell transplantation, and prophylactic donor lymphocyte transfusion in high-risk acute myeloid leukemia and myelodysplastic syndrome.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Aug-20, Volume: 23, Issue:24

    Topics: Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Chi-Square Distribution; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Logistic Models; Lymphocyte Transfusion; Male; Middle Aged; Myelodysplastic Syndromes; Pilot Projects; Prognosis; Proportional Hazards Models; Prospective Studies; Remission Induction; Stem Cell Transplantation; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Vidarabine

2005
Human stem cell factor-antibody [anti-SCF] enhances chemotherapy cytotoxicity in human CD34+ resistant myeloid leukaemia cells.
    Leukemia research, 2006, Volume: 30, Issue:3

    Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal; Antigens, CD34; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; bcl-2-Associated X Protein; Biomarkers, Tumor; Blast Crisis; Cell Line, Tumor; Chromosome Aberrations; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; Drug Synergism; Female; Humans; Leukemia, Myeloid, Acute; Male; Pilot Projects; Receptors, Cytokine; Stem Cell Factor; Treatment Outcome

2006
Medical ethics collides with public policy: LVAD for a patient with leukemia.
    The Annals of thoracic surgery, 2005, Volume: 80, Issue:3

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cardiomyopathies; Cost-Benefit Analysis; Cytarabine; Health Care Rationing; Heart-Assist Devices; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Public Policy; United States

2005
Methotrexate-induced status epilepticus.
    American journal of hematology, 2005, Volume: 80, Issue:1

    Topics: Antimetabolites, Antineoplastic; Cytarabine; Humans; Injections, Intraventricular; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Status Epilepticus; Treatment Outcome

2005
Bilateral ear Sweet's syndrome in a case with relapse acute myeloblastic leukemia.
    Leukemia research, 2006, Volume: 30, Issue:3

    Topics: Adult; Anti-Inflammatory Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Ear, External; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Methylprednisolone; Neutropenia; Recombinant Proteins; Recurrence; Sweet Syndrome; Vidarabine

2006
Usefulness of PKH fluorescent labelling to study leukemic cell proliferation with various cytostatic drugs or acetyl tetrapeptide--AcSDKP.
    BMC cancer, 2005, Sep-20, Volume: 5

    Topics: Amsacrine; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Bromodeoxyuridine; Cell Proliferation; Cytarabine; Daunorubicin; DNA; Etoposide; Flow Cytometry; Fluorescent Dyes; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hydrocarbons, Chlorinated; Leukemia; Leukemia, Myeloid, Acute; Microscopy, Fluorescence; Oligopeptides; Organic Chemicals; Radiation-Protective Agents

2005
High activity and incomplete cross resistance of nucleoside analogues cladribine and fludarabine versus Ara-C on leukemic cells from patients with AML.
    Therapeutic drug monitoring, 2005, Volume: 27, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Cladribine; Cytarabine; Drug Resistance, Neoplasm; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Vidarabine

2005
Potentiation of in vitro ara-C cytotoxicity by ribonucleotide reductase inhibitors, cyclin-dependent kinase modulators and the DNA repair inhibitor aphidicolin in paediatric acute myeloid leukaemia.
    British journal of haematology, 2005, Volume: 131, Issue:2

    Topics: Antimetabolites, Antineoplastic; Aphidicolin; Azacitidine; Child; Cyclin-Dependent Kinases; Cytarabine; Decitabine; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Leukemia, Myeloid, Acute; Leukocytes, Mononuclear; Nucleic Acid Synthesis Inhibitors; Ribonucleotide Reductases

2005
Treatment of acute myeloid leukemia during the second and third trimesters of pregnancy.
    Pharmacotherapy, 2005, Volume: 25, Issue:8

    Topics: Adult; Antimetabolites, Antineoplastic; Cesarean Section; Cytarabine; Female; Fetal Monitoring; Filgrastim; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Pregnancy; Pregnancy Complications, Neoplastic; Pregnancy Outcome; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Recombinant Proteins; Stem Cells

2005
Acute myeloid leukemia with near-triploid karyotype and extramedullary involvement of mediastinum.
    Bone marrow transplantation, 2005, Volume: 36, Issue:12

    Topics: Adult; Antineoplastic Agents; Bone Marrow Cells; Central Nervous System; Cytarabine; Disease Progression; Etoposide; Humans; Idarubicin; Karyotyping; Leukemia, Myeloid, Acute; Lymph Nodes; Lymphatic Metastasis; Male; Mediastinal Neoplasms; Mediastinum; Polyploidy; Prognosis; Stem Cell Transplantation; Tomography, X-Ray Computed

2005
Abrogation of heat shock protein 70 induction as a strategy to increase antileukemia activity of heat shock protein 90 inhibitor 17-allylamino-demethoxy geldanamycin.
    Cancer research, 2005, Nov-15, Volume: 65, Issue:22

    Topics: Apoptosis; bcl-2-Associated X Protein; Benzhydryl Compounds; Benzoquinones; Combined Modality Therapy; Cytarabine; Drug Synergism; Etoposide; HL-60 Cells; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; K562 Cells; Lactams, Macrocyclic; Leukemia, Myeloid, Acute; Mitochondria; Protein Conformation; Pyrrolidinones; Rifabutin; RNA, Small Interfering

2005
Mitoxantrone and cytosine arabinoside (ARA-C) in adult acute leukemia: an interim report.
    Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:4 Suppl

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Clinical Trials as Topic; Cytarabine; Drug Administration Schedule; Humans; Infusions, Intravenous; Leukemia; Leukemia, Myeloid, Acute; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome

1989
Low dose cytosine arabinoside in the treatment of acute non-lymphocytic leukemias and myelodysplastic syndromes.
    Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:4 Suppl

    Topics: Aged; Aged, 80 and over; Anemia, Refractory, with Excess of Blasts; Antimetabolites, Antineoplastic; Cytarabine; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Treatment Outcome

1989
Acute myelogenous leukemia--microenvironment interactions: role of endothelial cells and proteasome inhibition.
    Hematology (Amsterdam, Netherlands), 2005, Volume: 10, Issue:6

    Topics: Apoptosis; Boronic Acids; Bortezomib; Cell Communication; Cell Survival; Coculture Techniques; Cytarabine; Endothelial Cells; Humans; Leukemia, Myeloid, Acute; Proteasome Inhibitors; Pyrazines

2005
Concomitant hairy cell and acute myeloid leukemia.
    European journal of haematology, 2006, Volume: 76, Issue:1

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cytarabine; Daunorubicin; Genetic Predisposition to Disease; Humans; Leukemia, Hairy Cell; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasms, Second Primary; Recurrence; Stem Cell Transplantation

2006
Isolated extramedullary relapse after autologous bone marrow transplantation for acute myeloid leukemia: case report and review of the literature.
    American journal of hematology, 2006, Volume: 81, Issue:1

    Topics: Aged; Antimetabolites, Antineoplastic; Bone Marrow Transplantation; Central Nervous System; Chromosome Aberrations; Chromosomes, Human, Pair 8; Combined Modality Therapy; Cytarabine; Fatal Outcome; Female; Humans; Leukemia, Myeloid, Acute; Radiography; Recurrence; Registries; Transplantation, Autologous; Transplantation, Homologous

2006
Acute myelogenous leukemia in elderly patients not eligible for intensive chemotherapy: the dark side of the moon.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2006, Volume: 17, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Cytarabine; Female; Health Services for the Aged; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Male; Middle Aged; Palliative Care; Quality of Life; Retrospective Studies; Survival Analysis; Thioguanine

2006
Acute leukaemia presenting as vulvar ulcers in an adolescent girl.
    The Australian & New Zealand journal of obstetrics & gynaecology, 2005, Volume: 45, Issue:6

    Topics: Adolescent; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Diagnosis, Differential; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Risk Assessment; Treatment Outcome; Ulcer; Vulvar Diseases

2005
A cat with acute myeloblastic leukemia without maturation (M1) treated with combination chemotherapy.
    The Journal of veterinary medical science, 2006, Volume: 68, Issue:1

    Topics: Animals; Blood Transfusion; Bone Marrow Cells; Cat Diseases; Cats; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Fatal Outcome; Leukemia, Myeloid, Acute; Peroxidase; Prednisolone; Vincristine

2006
Successful treatment of rhinocerebral zygomycosis with a combination of caspofungin and liposomal amphotericin B.
    Haematologica, 2005, Volume: 90, Issue:12 Suppl

    Topics: Amphotericin B; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Caspofungin; Combined Modality Therapy; Cytarabine; Debridement; Diplopia; Drug Therapy, Combination; Echinocandins; Humans; Idarubicin; Immunocompromised Host; Leukemia, Myeloid, Acute; Lipopeptides; Male; Middle Aged; Mitoxantrone; Opportunistic Infections; Orbital Diseases; Peptides, Cyclic; Sinusitis; Zygomycosis

2005
Developmental clinical trials: building one step at a time.
    Leukemia research, 2006, Volume: 30, Issue:7

    Topics: Antineoplastic Agents; Apoptosis; Clinical Trials, Phase I as Topic; Cytarabine; Drug Resistance, Neoplasm; Humans; Leukemia, Myeloid, Acute; Neural Tube Defects; Pyridines; Research Design; Thiosemicarbazones

2006
Roles of protein C, protein S, and antithrombin III in acute leukemia.
    American journal of hematology, 2006, Volume: 81, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Antithrombin III; Asparaginase; Cyclophosphamide; Cytarabine; Disseminated Intravascular Coagulation; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Myocardial Infarction; Peripheral Nervous System Diseases; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Predictive Value of Tests; Prednisone; Protein C; Protein S; Thrombosis; Vincristine

2006
Unrelated cord blood transplantation after myeloablative conditioning in patients with acute leukemia aged between 50 and 55 years.
    Bone marrow transplantation, 2006, Volume: 37, Issue:8

    Topics: Acute Disease; Body Weight; Cord Blood Stem Cell Transplantation; Cytarabine; Female; Fetal Blood; Graft vs Host Disease; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Transplantation Conditioning

2006
Molecular response in two children with relapsed acute myeloid leukemia treated with a combination of gemtuzumab ozogamicin and cytarabine.
    Haematologica, 2006, Volume: 91, Issue:3

    Topics: Adolescent; Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Male; Neoplasm Recurrence, Local

2006
Stress-induced in vitro apoptosis of native human acute myelogenous leukemia (AML) cells shows a wide variation between patients and is associated with low BCL-2:Bax ratio and low levels of heat shock protein 70 and 90.
    Leukemia research, 2006, Volume: 30, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Apoptosis; bcl-2-Associated X Protein; Cell Survival; Cells, Cultured; Coculture Techniques; Cytarabine; Female; Flow Cytometry; Gene Expression Profiling; Granulocyte-Macrophage Colony-Stimulating Factor; HSC70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Leukemia, Myeloid, Acute; Leukocytes, Mononuclear; Male; Middle Aged; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger

2006
[Effectiveness analysis of HA based triple-drug regimen as induction chemotherapy in the treatment of acute myeloid leukemia and its relationship with karyotype].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2005, Volume: 26, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Disease-Free Survival; Female; Follow-Up Studies; Harringtonines; Humans; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Remission Induction; Retrospective Studies; Treatment Outcome

2005
The role of post-remission chemotherapy for older patients with acute myelogenous leukemia.
    Leukemia & lymphoma, 2006, Volume: 47, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bone Marrow Cells; Cytarabine; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunophenotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Remission Induction; Treatment Outcome

2006
Excretion of cytosine arabinoside in saliva after its administration at high doses.
    Anti-cancer drugs, 2006, Volume: 17, Issue:5

    Topics: Adult; Antimetabolites, Antineoplastic; Cytarabine; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Middle Aged; Myelodysplastic Syndromes; Saliva; Time Factors

2006
Synergistic effects of troglitazone in combination with cytotoxic agents in acute myelogenous leukaemia cells.
    Leukemia research, 2006, Volume: 30, Issue:11

    Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromans; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Etoposide; HL-60 Cells; Humans; Inhibitory Concentration 50; Leukemia, Myeloid, Acute; Structure-Activity Relationship; Thiazolidinediones; Troglitazone; U937 Cells

2006
[Drug sensitivity of tumor cells in varieties of acute childhood leukemia].
    Voprosy onkologii, 2005, Volume: 51, Issue:5

    Topics: Antigens, CD34; Antineoplastic Agents; Apoptosis; Asparagine; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Tumor Cells, Cultured; Vincristine

2005
Homoharringtonine in combination with cytarabine and aclarubicin resulted in high complete remission rate after the first induction therapy in patients with de novo acute myeloid leukemia.
    Leukemia, 2006, Volume: 20, Issue:8

    Topics: Aclarubicin; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Follow-Up Studies; Harringtonines; Homoharringtonine; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

2006
Acute myeloblastic leukemia in a patient with hereditary protein C deficiency.
    Internal medicine (Tokyo, Japan), 2006, Volume: 45, Issue:11

    Topics: Aclarubicin; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Enterocolitis, Pseudomembranous; Fatal Outcome; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Middle Aged; Protein C Deficiency

2006
Ex vivo activity of thalidomide in childhood acute leukemia.
    Leukemia & lymphoma, 2006, Volume: 47, Issue:6

    Topics: Angiogenesis Inhibitors; Cell Cycle; Child; Child, Preschool; Cytarabine; Female; Humans; Immunophenotyping; Infant; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Tetrazolium Salts; Thalidomide; Thiazoles

2006
Treatment of acute myeloid leukemia in older adults: time to reflect?
    Leukemia & lymphoma, 2006, Volume: 47, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bone Marrow Cells; Cytarabine; Disease-Free Survival; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunophenotyping; Leukemia, Myeloid, Acute; Mitoxantrone; Remission Induction; Treatment Outcome

2006
Predictable prognostic factor of CD56 expression in patients with acute myeloid leukemia with t(8:21) after high dose cytarabine or allogeneic hematopoietic stem cell transplantation.
    American journal of hematology, 2007, Volume: 82, Issue:1

    Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Biomarkers, Tumor; CD56 Antigen; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Cytarabine; Disease-Free Survival; Female; Gene Expression Regulation, Leukemic; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Predictive Value of Tests; Recurrence; Remission Induction; Retrospective Studies; Survival Rate; Translocation, Genetic; Transplantation, Homologous

2007
Acute myelogenous leukemia associated with Ollier disease.
    Pediatric blood & cancer, 2008, Volume: 50, Issue:3

    Topics: Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Chromosomes, Human, Pair 14; Chromosomes, Human, Pair 21; Cytarabine; Daunorubicin; Enchondromatosis; Etoposide; Gemtuzumab; Graft vs Host Disease; Humans; Infant; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Neoplastic Syndromes, Hereditary; Translocation, Genetic

2008
Chemopotentiating effects of a novel NAD biosynthesis inhibitor, FK866, in combination with antineoplastic agents.
    European journal of medical research, 2006, Aug-30, Volume: 11, Issue:8

    Topics: Acrylamides; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Cell Death; Cell Line, Tumor; Cell Survival; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Combinations; Humans; K562 Cells; Leukemia, Myeloid, Acute; Melphalan; Methylnitronitrosoguanidine; Monocytes; NAD; Piperidines

2006
Aclarubicin plus behenoyl cytarabine and prednisolone for previously treated acute myeloid leukemia patients.
    Leukemia & lymphoma, 2006, Volume: 47, Issue:10

    Topics: Aclarubicin; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisolone; Salvage Therapy; Stem Cell Transplantation; Transplantation, Homologous; Treatment Outcome

2006
Neutrophilic eccrine hidradenitis masquerading as facial cellulitis.
    Journal of the American Academy of Dermatology, 2007, Volume: 56, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Cellulitis; Cytarabine; Diagnosis, Differential; Facial Dermatoses; Female; Follow-Up Studies; Hidradenitis; Humans; Idarubicin; Immunohistochemistry; Leukemia, Myeloid, Acute; Risk Assessment

2007
Increased mortality with FLA compared with ADE chemotherapy in high-risk AML.
    Blood, 2006, Dec-01, Volume: 108, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Retrospective Studies; Risk Factors; Survival Rate; Treatment Outcome

2006
Mitoxantrone-related acute myeloblastic leukaemia in a patient with metastatic hormone-refractory prostate cancer.
    Anti-cancer drugs, 2007, Volume: 18, Issue:2

    Topics: Androgens; Antimetabolites, Antineoplastic; Antineoplastic Agents; Cytarabine; Humans; In Situ Hybridization; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Neoplasm Metastasis; Prostatic Neoplasms

2007
Flushing out of cerebrospinal fluid as a therapy for acute cerebellar dysfunction caused by high dose of cytosine arabinoside: a case report.
    Journal of pediatric hematology/oncology, 2006, Volume: 28, Issue:12

    Topics: Adolescent; Antimetabolites, Antineoplastic; Cerebellar Diseases; Cerebrospinal Fluid; Cytarabine; Humans; Leukemia, Myeloid, Acute; Male

2006
Oridonin, a diterpenoid extracted from medicinal herbs, targets AML1-ETO fusion protein and shows potent antitumor activity with low adverse effects on t(8;21) leukemia in vitro and in vivo.
    Blood, 2007, Apr-15, Volume: 109, Issue:8

    Topics: Animals; Antineoplastic Agents; Apoptosis; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Core Binding Factor Alpha 2 Subunit; Cytarabine; Diterpenes; Diterpenes, Kaurane; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Leukemia, Myeloid, Acute; Mice; Mice, Nude; Neoplasms, Experimental; Oncogene Proteins, Fusion; Plant Extracts; Plants, Medicinal; RUNX1 Translocation Partner 1 Protein; Translocation, Genetic; U937 Cells

2007
A microarray study of altered gene expression after cytarabine resistance in acute myeloid leukemia.
    Leukemia, 2007, Volume: 21, Issue:5

    Topics: Amyloid beta-Protein Precursor; Antimetabolites, Antineoplastic; Cytarabine; DNA Mismatch Repair; Drug Resistance, Neoplasm; Gene Expression Profiling; Humans; Leukemia, Myeloid, Acute; Oligonucleotide Array Sequence Analysis; Proto-Oncogene Proteins c-bcl-2

2007
Fludarabine-mediated circumvention of cytarabine resistance is associated with fludarabine triphosphate accumulation in cytarabine-resistant leukemic cells.
    International journal of hematology, 2007, Volume: 85, Issue:2

    Topics: Arabinofuranosylcytosine Triphosphate; Cytarabine; Drug Resistance, Neoplasm; Drug Synergism; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Vidarabine

2007
The insulin-like growth factor-I receptor kinase inhibitor NVP-AEW541 induces apoptosis in acute myeloid leukemia cells exhibiting autocrine insulin-like growth factor-I secretion.
    Leukemia, 2007, Volume: 21, Issue:5

    Topics: Apoptosis; Cyclin-Dependent Kinase Inhibitor p27; Cytarabine; Down-Regulation; Etoposide; HL-60 Cells; Humans; Insulin-Like Growth Factor I; Intracellular Signaling Peptides and Proteins; Leukemia, Myeloid, Acute; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Pyrimidines; Pyrroles; Receptor, IGF Type 1

2007
Complex chromosome 8;21 translocation with associated hyperdiploidy in acute myeloid leukemia (FAB-M2).
    Pediatric blood & cancer, 2008, Volume: 50, Issue:3

    Topics: Aneuploidy; Antineoplastic Combined Chemotherapy Protocols; Child; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Core Binding Factor Alpha 2 Subunit; Cytarabine; Cytogenetic Analysis; Etoposide; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Nucleic Acid Hybridization; Oncogene Proteins, Fusion; Polymerase Chain Reaction; RUNX1 Translocation Partner 1 Protein; Translocation, Genetic

2008
"Flushing out" cytosine arabinoside from CSF to reverse neurotoxicity.
    Journal of pediatric hematology/oncology, 2007, Volume: 29, Issue:4

    Topics: Adolescent; Antimetabolites, Antineoplastic; Cerebellar Diseases; Cerebrospinal Fluid; Cytarabine; Humans; Leukemia, Myeloid, Acute; Male

2007
Diffuse alveolar damage and hemorrhage in acute myelogenous leukemia treated with corticosteroids.
    Connecticut medicine, 2007, Volume: 71, Issue:4

    Topics: Adrenal Cortex Hormones; Aged; Antibiotics, Antineoplastic; Cytarabine; Daunorubicin; Female; Hemorrhage; Humans; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Lung Diseases; Pulmonary Alveoli; Radiography

2007
[The standard treatments for patients with hematological malignancies in Japan].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:5

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Administration Schedule; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Lymphoma; Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; Melphalan; Multiple Myeloma; Prednisone; Rituximab; Survival Rate; Vincristine

2007
Complete remission induced by gemtuzumab ozogamicin in a Jehovah's Witness patient with acute myelogenous leukemia.
    International journal of hematology, 2007, Volume: 85, Issue:5

    Topics: Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Gemtuzumab; Humans; Jehovah's Witnesses; Leukemia, Myeloid, Acute; Leukocyte Count; Middle Aged; Organic Chemicals; Remission Induction; Severity of Illness Index

2007
[Acute myelogenous leukemia with multilineage myelodysplasia, positive direct Coombs test, and elevated levels of platelet-associated IgG].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2007, Volume: 48, Issue:5

    Topics: Aclarubicin; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Platelets; Coombs Test; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Immunoglobulin G; Leukemia, Myeloid, Acute; Male; Myelodysplastic Syndromes; Pancytopenia; Prednisolone; Treatment Outcome

2007
Cytosine-arabinoside induced bradycardia in patient with non-Hodgkin lymphoma: a case report.
    Leukemia & lymphoma, 2007, Volume: 48, Issue:6

    Topics: Antimetabolites, Antineoplastic; Bradycardia; Cytarabine; Electrocardiography; Humans; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Middle Aged

2007
A new intensive induction schedule, including high-dose Idarubicin, high-dose Aracytin and Amifostine, in older AML patients: feasibility and long-term results in 42 patients.
    Experimental hematology, 2007, Volume: 35, Issue:7

    Topics: Aged; Amifostine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Treatment Outcome

2007
Biphenotypic acute leukaemia: a case series.
    British journal of haematology, 2007, Volume: 138, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Female; Humans; Immunophenotyping; Leukemia; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome; Vincristine

2007
Aberrant phenotype of plasmacytoid monocytes in acute myeloid leukemia.
    American journal of hematology, 2008, Volume: 83, Issue:5

    Topics: Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Arthritis, Rheumatoid; Bone Marrow; Cell Differentiation; Clone Cells; Cytarabine; Fatal Outcome; Humans; Idarubicin; Immunophenotyping; Leukemia, Myeloid, Acute; Male; Megakaryocytes; Methotrexate; Middle Aged; Monocytes; Neoplasm Proteins; Neoplastic Stem Cells

2008
Acute myeloid leukaemia presenting as recurrent generalized urticaria in infancy.
    European journal of pediatrics, 2008, Volume: 167, Issue:6

    Topics: Antimetabolites, Antineoplastic; Cytarabine; Diagnosis, Differential; Humans; Idarubicin; Infant; Leukemia, Myeloid, Acute; Male; Recurrence; Urticaria

2008
Disseminated intravascular coagulation in acute leukemia at presentation and during induction therapy.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2007, Volume: 13, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Disseminated Intravascular Coagulation; Female; Humans; Incidence; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Partial Thromboplastin Time; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prospective Studies; Remission Induction; Vincristine

2007
Modulation of cell apoptosis by AIR.
    Leukemia, 2007, Volume: 21, Issue:12

    Topics: Antibodies; Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; Cytarabine; DNA, Complementary; Endogenous Retroviruses; Humans; Jurkat Cells; Leukemia, Myeloid, Acute; Leukocytes, Mononuclear; Maleates; Oligodeoxyribonucleotides, Antisense; RNA, Messenger; Thionucleotides; Transfection

2007
Results of compassionate therapy with intrathecal depot liposomal cytarabine in acute myeloid leukemia meningeosis.
    International journal of hematology, 2007, Volume: 86, Issue:1

    Topics: Adult; Antimetabolites, Antineoplastic; Cytarabine; Female; Humans; Injections, Spinal; Leukemia, Myeloid, Acute; Leukemic Infiltration; Liposomes; Male; Meninges; Middle Aged; Retrospective Studies; Spain; United Kingdom

2007
Trisomy 21 as a sole acquired abnormality in an adult Omani patient with CD7- and CD9-positive acute myeloid leukemia.
    Archives of medical research, 2007, Volume: 38, Issue:7

    Topics: Adult; Antigens, CD; Antigens, CD7; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Cytogenetic Analysis; Daunorubicin; Down Syndrome; Humans; Karyotyping; Leukemia, Myeloid, Acute; Male; Membrane Glycoproteins; Remission Induction; Tetraspanin 29; Treatment Outcome

2007
Upregulation of multi drug resistance genes in doxorubicin resistant human acute myelogeneous leukemia cells and reversal of the resistance.
    Hematology (Amsterdam, Netherlands), 2007, Volume: 12, Issue:6

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Cytarabine; Doxorubicin; Drug Resistance, Multiple; Drug Therapy, Combination; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Lewis X Antigen; Multidrug Resistance-Associated Proteins; Receptors, IgG; Up-Regulation

2007
The prognostic significance of leukemic cells clearance kinetics evaluation during the initial course of induction therapy with HAD (homoharringtonine, cytosine arabinoside, daunorubicin) in patients with de novo acute myeloid leukemia.
    American journal of hematology, 2008, Volume: 83, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Harringtonines; Homoharringtonine; Humans; Leukemia, Myeloid, Acute; Male; Metabolic Clearance Rate; Middle Aged; Prognosis; Retrospective Studies; Survival Analysis

2008
Combination chemotherapy with low-dose cytarabine, homoharringtonine, and granulocyte colony-stimulating factor priming in patients with relapsed or refractory acute myeloid leukemia.
    American journal of hematology, 2008, Volume: 83, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase I as Topic; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Harringtonines; Homoharringtonine; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neutropenia; Retrospective Studies; Treatment Outcome

2008
Chemotherapeutic treatment of bone marrow stromal cells strongly affects their protective effect on acute myeloid leukemia cell survival.
    Leukemia & lymphoma, 2008, Volume: 49, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Bone Marrow; Cell Proliferation; Cell Survival; Cytarabine; Drug Design; Flow Cytometry; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Stromal Cells; Tumor Cells, Cultured

2008
Advanced age and high initial WBC influence the outcome of inv(3) (q21q26)/t(3;3) (q21;q26) positive AML.
    Leukemia & lymphoma, 2007, Volume: 48, Issue:11

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Chromosome Inversion; Chromosomes, Human, Pair 3; Cohort Studies; Cytarabine; Danazol; Female; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Humans; Karyotyping; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Mitoxantrone; Prognosis; Survival Analysis; Tamoxifen; Translocation, Genetic

2007
Association of 3q21q26 syndrome and late-appearing Philadelphia chromosome in acute myeloid leukemia.
    Leukemia, 2008, Volume: 22, Issue:4

    Topics: Chromosomes, Human, Pair 3; Cytarabine; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Middle Aged; Philadelphia Chromosome; Syndrome; Time Factors

2008
[Efficacy and safety of induction chemotherapy consisting of anthracycline for 3 days and cytarabine for 7 days in elderly patients with acute myeloid leukemia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:10

    Topics: Aged; Anthracyclines; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Remission Induction

2007
Combination therapy of an anticancer drug with the FNIII14 peptide of fibronectin effectively overcomes cell adhesion-mediated drug resistance of acute myelogenous leukemia.
    Leukemia, 2008, Volume: 22, Issue:2

    Topics: Animals; Antineoplastic Agents; Bone Marrow; Cell Adhesion; Cell Line, Tumor; Cytarabine; Drug Resistance; Drug Therapy, Combination; Fibronectins; Humans; Integrin beta1; Leukemia, Myeloid, Acute; Mice; Neoplasm, Residual; Peptide Fragments; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured

2008
[A short duration treatment with intensive consolidation therapy for patients with acute myelogenous leukemia--13 year experience in a single institute].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Etoposide; Evidence-Based Medicine; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Mitoxantrone; Prednisolone; Prednisone; Quality of Life; Retrospective Studies; Survival Rate; Vincristine

2007
Management of acute myeloid leukaemia--5 years experience at Armed Forces Bone Marrow Transplant Centre, Rawalpindi.
    JPMA. The Journal of the Pakistan Medical Association, 2007, Volume: 57, Issue:9

    Topics: Adolescent; Adult; Anthracyclines; Antineoplastic Agents; Child; Cytarabine; Disease Progression; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Military Medicine; Military Personnel; Pakistan; Retrospective Studies; Time Factors; Treatment Outcome; Tretinoin

2007
Significance of age in acute myeloid leukemia patients younger than 30 years: a common analysis of the pediatric trials AML-BFM 93/98 and the adult trials AMLCG 92/99 and AMLSG HD93/98A.
    Cancer, 2008, Feb-01, Volume: 112, Issue:3

    Topics: Adolescent; Adult; Aging; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Bone Marrow; Child; Child, Preschool; Clinical Trials as Topic; Cytarabine; Etoposide; Female; Humans; Idarubicin; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Male; Prognosis; Risk Factors; Survival Analysis; Treatment Outcome

2008
Cladribine combined with high doses of arabinoside cytosine, mitoxantrone, and G-CSF (CLAG-M) is a highly effective salvage regimen in patients with refractory and relapsed acute myeloid leukemia of the poor risk: a final report of the Polish Adult Leukem
    European journal of haematology, 2008, Volume: 80, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Multivariate Analysis; Odds Ratio; Poland; Recurrence; Salvage Therapy; Stem Cell Transplantation; Treatment Outcome

2008
[Effects of FLAG protocol in treatment of the first time induced non-remission acute myeloid leukemia].
    Zhongguo shi yan xue ye xue za zhi, 2007, Volume: 15, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Vidarabine; Young Adult

2007
[Analysis on prognosis and correlative factors of acute nonlymphocytic leukemia].
    Zhongguo shi yan xue ye xue za zhi, 2007, Volume: 15, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Harringtonines; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Tretinoin; Young Adult

2007
Early acute myeloblastic leukemia treatment for childhood myelodysplastic syndrome with t(3;5) (NPM/MLF1).
    Journal of pediatric hematology/oncology, 2007, Volume: 29, Issue:12

    Topics: Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Chromosomes, Human, Pair 3; Chromosomes, Human, Pair 5; Cyclophosphamide; Cytarabine; Doxorubicin; Humans; Leukemia, Myeloid, Acute; Male; Methotrexate; Oncogene Proteins, Fusion; Prednisone; Thioguanine; Translocation, Genetic; Treatment Outcome; Vincristine

2007
Therapy-related myelodysplastic syndrome and acute myeloid leukemia following treatment of acute myeloid leukemia: possible role of cytarabine.
    Leukemia research, 2008, Volume: 32, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents; Chromosome Aberrations; Chromosomes, Human, Pair 7; Cytarabine; Female; Humans; Immunophenotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes

2008
Relationship between in vitro chemosensitivity assessed with MTT assay and clinical outcomes in 103 patients with acute leukemia.
    The Korean journal of laboratory medicine, 2007, Volume: 27, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Child; Child, Preschool; Coloring Agents; Cytarabine; Daunorubicin; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; Female; Humans; Infant; Leukemia, Biphenotypic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tetrazolium Salts; Thiazoles; Treatment Outcome

2007
[Discrepant results of ABO type of red cells and serum in a patient with acute myelogenous leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2008, Volume: 49, Issue:1

    Topics: ABO Blood-Group System; Adult; Antineoplastic Combined Chemotherapy Protocols; Blood Grouping and Crossmatching; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Remission Induction

2008
Enhancement of the anti-tumor efficacy of a GM-CSF-secreting tumor cell immunotherapy in preclinical models by cytosine arabinoside.
    Experimental hematology, 2008, Volume: 36, Issue:3

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Combined Modality Therapy; Cytarabine; Disease Models, Animal; Female; Flow Cytometry; Gene Transfer Techniques; Granulocyte-Macrophage Colony-Stimulating Factor; Immunologic Memory; Immunotherapy; Injections, Intraperitoneal; Leukemia, Myeloid, Acute; Luciferases; Lymphopenia; Mice; Mice, Congenic; Mice, Inbred C57BL; Neoplasm Transplantation; Phenotype; Survival Rate; Time Factors; Treatment Outcome

2008
Therapeutic experience of adult acute myeloid leukemia in a single institution of China and its relationship with chromosome karyotype.
    Leukemia & lymphoma, 2008, Volume: 49, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; China; Cytarabine; Cytogenetic Analysis; Daunorubicin; Female; Harringtonines; Homoharringtonine; Humans; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Prognosis; Remission Induction; Retrospective Studies; Survival Analysis

2008
Two cases of post-liver transplant acute myeloid leukemia in Korean adults: review of bibliographies and comparison with post-renal transplant acute myeloid leukemia.
    Annals of hematology, 2008, Volume: 87, Issue:6

    Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Fatal Outcome; Female; Humans; Kidney Transplantation; Korea; Leukemia, Myeloid, Acute; Liver Transplantation; Male; Middle Aged; Treatment Outcome; Tretinoin

2008
Drug-induced hypersensitivity syndrome with rapid hematopoietic reconstitution during treatment for acute myeloid leukemia.
    Haematologica, 2008, Volume: 93, Issue:3

    Topics: Aged; Allopurinol; Anti-Infective Agents; Antibodies, Viral; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Drug Eruptions; Exanthema Subitum; Female; Fever; Hematopoiesis; Herpesvirus 6, Human; Histiocytosis; Humans; Idarubicin; Immunocompromised Host; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemic Infiltration; Middle Aged; Skin; Virus Activation

2008
Mutated and non-mutated TP53 as targets in the treatment of leukaemia.
    British journal of haematology, 2008, Volume: 141, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Death; Chromosome Aberrations; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Synergism; Furans; Genes, p53; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Membrane Proteins; Mutation; Nerve Tissue Proteins; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Vidarabine

2008
Acute myeloid leukaemia blast cells with a tyrosine kinase domain mutation of FLT3 are less sensitive to lestaurtinib than those with a FLT3 internal tandem duplication.
    British journal of haematology, 2008, Volume: 141, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carbazoles; Cytarabine; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; fms-Like Tyrosine Kinase 3; Furans; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Neoplastic Stem Cells; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Tandem Repeat Sequences

2008
Alleviation of the drug-resistant phenotype in idarubicin and cytosine arabinoside double-resistant acute myeloid leukemia cells by indomethacin.
    International journal of oncology, 2008, Volume: 32, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; ATP-Binding Cassette Transporters; Cell Line, Tumor; Cytarabine; Drug Resistance, Neoplasm; Humans; Idarubicin; Indomethacin; Leukemia, Myeloid, Acute; Multidrug Resistance-Associated Proteins; Phenotype

2008
Heat shock protein 90 inhibition is cytotoxic to primary AML cells expressing mutant FLT3 and results in altered downstream signalling.
    British journal of haematology, 2008, Volume: 141, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzoquinones; Cell Death; Cytarabine; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; fms-Like Tyrosine Kinase 3; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Leukemia, Myeloid, Acute; MAP Kinase Signaling System; Middle Aged; Neoplasm Proteins; Signal Transduction; Tumor Cells, Cultured

2008
Relapse and death during first remission in acute myeloid leukemia.
    Haematologica, 2008, Volume: 93, Issue:4

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Remission Induction; Risk; Survival Analysis; Treatment Outcome

2008
[Therapeutic effect of priming induction regimen of CAG for newly diagnosed acute myeloid leukemia in elderly patients].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2008, Volume: 33, Issue:3

    Topics: Aclarubicin; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Remission Induction

2008
[A rare complication of immunosuppression: digestive aspergillosis].
    Gastroenterologie clinique et biologique, 2008, Volume: 32, Issue:2

    Topics: Aspergillosis; Cytarabine; Duodenitis; Duodenoscopy; Enteritis; Female; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Jejunal Diseases; Leukemia, Myeloid, Acute; Middle Aged; Opportunistic Infections

2008
Increase sensitivity to chemotherapeutical agents and cytoplasmatic interaction between NPM leukemic mutant and NF-kappaB in AML carrying NPM1 mutations.
    Leukemia, 2008, Volume: 22, Issue:6

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Bone Marrow; Cell Nucleus; Cytarabine; Cytoplasm; Daunorubicin; Electrophoretic Mobility Shift Assay; Etoposide; Flow Cytometry; Fluorescent Antibody Technique; Gene Expression Regulation, Leukemic; Humans; Immunoprecipitation; Leukemia, Myeloid, Acute; Mutation; NF-kappa B; Nuclear Proteins; Nucleophosmin; Tumor Cells, Cultured

2008
Acute myeloid leukemia presenting as one-and-a-half syndrome.
    The American journal of emergency medicine, 2008, Volume: 26, Issue:4

    Topics: Adult; Antineoplastic Agents; Brain Stem Infarctions; Cytarabine; Diagnosis, Differential; Female; Humans; Leukapheresis; Leukemia, Myeloid, Acute; Ocular Motility Disorders; Syndrome

2008
The expression of DeltaNTP73, TATP73 and TP53 genes in acute myeloid leukaemia is associated with recurrent cytogenetic abnormalities and in vitro susceptibility to cytarabine cytotoxicity.
    British journal of haematology, 2008, Volume: 142, Issue:1

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Chromosome Aberrations; Cytarabine; DNA-Binding Proteins; Drug Resistance, Neoplasm; Gene Expression; Gene Rearrangement; Genes, p53; Humans; Leukemia, Myeloid, Acute; Nuclear Proteins; Polymerase Chain Reaction; Recurrence; Tumor Suppressor Proteins

2008
Difficulty of peripheral blood stem cell collection after multiple consolidation therapy in acute myeloid leukemia.
    Journal of clinical and experimental hematopathology : JCEH, 2008, Volume: 48, Issue:1

    Topics: Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cells; Humans; Lenograstim; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Neoplasm, Residual; Peripheral Blood Stem Cell Transplantation; Recombinant Proteins; Tissue and Organ Harvesting

2008
Unexpected CNS localization in M2 acute myeloid leukemia: a link with past heroin addiction?
    American journal of hematology, 2008, Volume: 83, Issue:8

    Topics: Central Nervous System Neoplasms; Cytarabine; Heroin Dependence; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Premedication

2008
Improved outcome of children with acute myeloid leukemia treated on 2 consecutive protocols.
    Saudi medical journal, 2008, Volume: 29, Issue:5

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Doxorubicin; Etoposide; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Retrospective Studies; Saudi Arabia; Survival Rate; Treatment Outcome; Vidarabine

2008
Treatment of therapy-related acute myeloid leukemia occurring in elderly non-Hodgkin lymphoma patients with low-dose cytarabine, aclarubicin and granulocyte colony-stimulating factor.
    Leukemia research, 2009, Volume: 33, Issue:1

    Topics: Aclarubicin; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Neoplasms, Second Primary

2009
Suppression of p38-stress kinase sensitizes quiescent leukemic cells to anti-mitotic drugs by inducing proliferative responses in them.
    Cancer biology & therapy, 2008, Volume: 7, Issue:8

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antimetabolites, Antineoplastic; Cell Line, Tumor; Cell Proliferation; Culture Media, Serum-Free; Cytarabine; Humans; Immunoglobulin Heavy Chains; Ki-67 Antigen; Leukemia, Myeloid, Acute; p38 Mitogen-Activated Protein Kinases; Stress, Physiological

2008
Long-term follow-up of allogeneic hematopoietic stem cell transplantation for de novo acute myelogenous leukemia with a conditioning regimen of total body irradiation and granulocyte colony-stimulating factor-combined high-dose cytarabine.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2008, Volume: 14, Issue:6

    Topics: Adolescent; Adult; Bone Marrow Transplantation; Cytarabine; Disease-Free Survival; Female; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Infusions, Intravenous; Kaplan-Meier Estimate; Lenograstim; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Male; Middle Aged; Peripheral Blood Stem Cell Transplantation; Recombinant Proteins; Remission Induction; Retrospective Studies; Survival Analysis; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Whole-Body Irradiation

2008
CI-994 (N-acetyl-dinaline) in combination with conventional anti-cancer agents is effective against acute myeloid leukemia in vitro and in vivo.
    Oncology reports, 2008, Volume: 19, Issue:6

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Blood Cell Count; Cell Proliferation; Cytarabine; Daunorubicin; In Vitro Techniques; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Phenylenediamines; Rats; Rats, Inbred BN

2008
Successful combination therapy with infusion of allogenetic bone marrow mesenchymal stem cells and CAG regimen in hypoplastic relapsed acute myelogenous leukemia.
    Leukemia research, 2008, Volume: 32, Issue:11

    Topics: Aclarubicin; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells; Cytarabine; Female; Flow Cytometry; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Mesenchymal Stem Cell Transplantation; Middle Aged; Neoplasm Recurrence, Local; Remission Induction; Transplantation, Homologous

2008
Isolation and characterization of a deoxycytidine kinase-deficient human promyelocytic leukemic cell line highly resistant to 1-beta-D- arabinofuranosylcytosine.
    Cancer research, 1984, Volume: 44, Issue:11

    Topics: Cell Division; Cell Line; Cytarabine; Cytidine Deaminase; Deoxycytidine Kinase; Drug Resistance; Humans; Kinetics; Leukemia, Myeloid, Acute; Mutation; Phosphotransferases; Pyrimidines; Thymidine Kinase

1984
Disturbances of desmofibrinogenesis in pateints suffering from acute myeloblastic leukemia.
    Folia haematologica (Leipzig, Germany : 1928), 1980, Volume: 107, Issue:1

    Topics: Adolescent; Adult; Cytarabine; Daunorubicin; Factor XIII; Fibrinogen; Free Radicals; Humans; Leukemia, Myeloid, Acute; Middle Aged; Solubility

1980
[Individual chemotherapy in blastic leukemias (AML)].
    Folia haematologica (Leipzig, Germany : 1928), 1981, Volume: 108, Issue:2

    Topics: Adult; Cyclophosphamide; Cytarabine; HLA Antigens; Humans; Leukemia, Myeloid, Acute; Leukocyte Transfusion; Methods; Platelet Transfusion; Prednisolone; Vincristine

1981
[Experiences in the induction of remission and in maintenance therapy in acute myeloblastic leukemia in adults with the RAMPO scheme].
    Folia haematologica (Leipzig, Germany : 1928), 1981, Volume: 108, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisolone; Vincristine

1981
8;21 translocation in acute granulocytic leukaemia: cytological, cytochemical and clinical features.
    British journal of haematology, 1984, Volume: 56, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Child; Child, Preschool; Chromosomes, Human, 21-22 and Y; Chromosomes, Human, 6-12 and X; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Staining and Labeling; Thioguanine; Translocation, Genetic

1984
Seven day cytosine arabinoside administered subcutaneously plus daunorubicin for remission induction in AML.
    Folia haematologica (Leipzig, Germany : 1928), 1983, Volume: 110, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Humans; Injections, Intravenous; Injections, Subcutaneous; Leukemia, Myeloid, Acute; Male; Middle Aged

1983
Prolonged survival in acute myelogenous leukaemia without maintenance chemotherapy.
    Lancet (London, England), 1984, Apr-21, Volume: 1, Issue:8382

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Thioguanine; Time Factors

1984
Hemopoietic stem cells: their roles in human leukemia and certain continuous cell lines.
    Journal of cellular physiology. Supplement, 1984, Volume: 3

    Topics: Azacitidine; Cell Differentiation; Cell Line; Clone Cells; Colony-Forming Units Assay; Cytarabine; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute

1984
Modulation of HLA-DR antigens expression in human myeloid leukaemia cells by cytarabine and 5-aza-2'-deoxycytidine.
    Lancet (London, England), 1984, Oct-13, Volume: 2, Issue:8407

    Topics: Azacitidine; Cells, Cultured; Cytarabine; Cytidine Triphosphate; Cytosine Nucleotides; Gene Expression Regulation; Histocompatibility Antigens Class II; HLA-DR Antigens; Humans; Leukemia, Myeloid, Acute

1984
[Treatment of acute myeloid leukemia].
    Folia haematologica (Leipzig, Germany : 1928), 1984, Volume: 111, Issue:2

    Topics: Adult; Aminoacridines; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Daunorubicin; Delayed-Action Preparations; Doxorubicin; Drug Administration Schedule; Humans; Leukemia, Myeloid, Acute; Prednisone; Recurrence; Thioguanine; Vincristine

1984
Neutrophilic eccrine hidradenitis: a distinctive rash associated with cytarabine therapy and acute leukemia.
    Journal of the American Academy of Dermatology, 1984, Volume: 11, Issue:4 Pt 1

    Topics: Cytarabine; Drug Eruptions; Humans; Inflammation; Leukemia, Myeloid, Acute; Male; Middle Aged; Neutrophils; Skin; Sweat Gland Diseases

1984
Prognostic factors in adult patients with acute leukemia.
    The Tokai journal of experimental and clinical medicine, 1983, Volume: 8, Issue:5-6

    Topics: Acute Disease; Adolescent; Adult; Aged; Chromosome Aberrations; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Prednisolone; Prognosis; Vincristine; Zinostatin

1983
Effects of tetrahydrouridine on the uptake and metabolism of 1-beta-D-arabinofuranosylcytosine in human normal and leukemic cells.
    Cancer research, 1980, Volume: 40, Issue:7

    Topics: Bone Marrow; Cells, Cultured; Cytarabine; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Phosphotransferases; Tetrahydrouridine; Uridine

1980
[Ring-shaped inclusions in an uncommon variety of acute myeloid leukemia (author's transl)].
    Blut, 1981, Volume: 43, Issue:1

    Topics: Adolescent; Cytarabine; Daunorubicin; Female; Humans; Inclusion Bodies; Leukemia, Myeloid, Acute; Microscopy, Electron; Vincristine

1981
Histomorphologic study of bone marrow in acute leukemia following chemotherapy and autologous bone marrow transplantation.
    Tumori, 1983, Jun-30, Volume: 69, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bone Marrow; Bone Marrow Transplantation; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisolone; Thioguanine; Time Factors; Transplantation, Autologous; Vincristine; Whole-Body Irradiation

1983
Experience with intermediate and high dose cytosine arabinoside in refractory acute leukaemia.
    Onkologie, 1983, Volume: 6, Issue:4

    Topics: Adult; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male

1983
Haemopoietic patterns of acute leukaemia in remission: CFU-E and CFU-GM colony formation.
    Acta haematologica, 1983, Volume: 70, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colony-Forming Units Assay; Cytarabine; Daunorubicin; Drug Therapy, Combination; Erythrocytes; Female; Granulocytes; Hematopoietic Stem Cells; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Macrophages; Thioguanine; Time Factors

1983
[ACNP therapy for DCMP-resistant acute leukemia (author's transl)].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1981, Volume: 22, Issue:10

    Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Agents; Cytarabine; Doxorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisolone; Zinostatin

1981
Idiopathic refractory sideroachrestic anemia (IRSA) progressing to acute mixed lymphoblastic-myelomonoblastic leukemia. Case report and review of the literature.
    Blut, 1983, Volume: 46, Issue:1

    Topics: Aged; Anemia, Sideroblastic; Bone Marrow Examination; Cerebrospinal Fluid; Cytarabine; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Pneumonia; Prednisone; Thioguanine; Tuberculosis, Miliary; Vincristine

1983
Extensive pulmonary infiltration by leukemic blast cells treated with irradiation.
    Canadian Medical Association journal, 1983, Feb-15, Volume: 128, Issue:4

    Topics: Adult; Cerebral Hemorrhage; Cytarabine; Daunorubicin; Female; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Lung; Thioguanine

1983
Acute cerebellar dysfunction with high-dose ARA-C therapy.
    Cancer, 1983, Feb-01, Volume: 51, Issue:3

    Topics: Aged; Brain Diseases; Cerebellum; Cytarabine; Humans; Leukemia, Myeloid, Acute; Male; Purkinje Cells

1983
Ocular toxicity from high-dose cytosine arabinoside.
    Cancer, 1983, Feb-01, Volume: 51, Issue:3

    Topics: Cornea; Corneal Opacity; Cytarabine; DNA; Drug Administration Schedule; Eye Diseases; Female; Humans; Leukemia, Myeloid, Acute; Middle Aged; Visual Acuity

1983
Acute myelomonocytic leukemia in a dog.
    Journal of the American Veterinary Medical Association, 1983, Jan-15, Volume: 182, Issue:2

    Topics: Animals; Antineoplastic Agents; Cytarabine; Dog Diseases; Dogs; Doxorubicin; Drug Therapy, Combination; Female; Leukemia, Myeloid, Acute; Thioguanine; Vincristine

1983
Therapeutic leukapheresis for hyperleukocytosis in acute myelocytic leukemia.
    Medical and pediatric oncology, 1983, Volume: 11, Issue:2

    Topics: Adolescent; Adult; Aged; Child; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukapheresis; Leukemia, Myeloid, Acute; Leukocyte Count; Leukocytosis; Middle Aged

1983
Plasma fibronectin deficiency during chemotherapy of acute myeloid leukaemia.
    Scandinavian journal of haematology, 1983, Volume: 30, Issue:3

    Topics: Adult; Aged; Bronchopneumonia; Cytarabine; Daunorubicin; Female; Fever; Fibronectins; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Thioguanine

1983
Acute nonlymphocytic leukemia and acute aplastic anemia. The simultaneous occurrence in marital partners.
    Archives of internal medicine, 1983, Volume: 143, Issue:6

    Topics: Adult; Anemia, Aplastic; Animals; Antilymphocyte Serum; Cats; Cytarabine; Doxorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Marriage; Time Factors

1983
Pericarditis as presenting manifestation of acute nonlymphocytic leukemia in a young child.
    Cancer, 1983, Jul-15, Volume: 52, Issue:2

    Topics: Acute Disease; Child, Preschool; Cytarabine; Diagnosis, Differential; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Pericarditis; Thioguanine

1983
Relationship between protein binding and extravascular drug concentrations of a water-soluble drug, cytosine arabinoside.
    Journal of the Royal Society of Medicine, 1983, Volume: 76, Issue:5

    Topics: Blood Proteins; Cytarabine; Humans; Leukemia, Myeloid, Acute; Protein Binding; Saliva

1983
[Changes of therapy results in acute leukemia under different treatment schedules with special reference to gnotobiotic measures].
    Klinische Wochenschrift, 1983, Apr-01, Volume: 61, Issue:7

    Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents; Asparaginase; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Patient Isolation; Prednisolone; Thioguanine; Vincristine

1983
[Drug sensitivity of human acute myelocytic leukemia cells (HL-60) and normal human myelocytes (CFU-C) in a co-culture].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1983, Volume: 10, Issue:4 Pt 2

    Topics: Adult; Cells, Cultured; Cytarabine; Daunorubicin; Drug Resistance; Female; Head and Neck Neoplasms; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Vincristine

1983
[Adriamycin-aclacinomycin therapy (AA therapy) for acute leukemia unresponsive to BH-AC-DMP therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1983, Volume: 10, Issue:6

    Topics: Aclarubicin; Adolescent; Adult; Aged; Cytarabine; Daunorubicin; Doxorubicin; Drug Resistance; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Naphthacenes; Prednisolone

1983
Chemotherapy for acute myelogenous leukemia in children and adults: VAPA update.
    Blood, 1983, Volume: 62, Issue:2

    Topics: Adult; Agranulocytosis; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child; Cytarabine; Doxorubicin; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Prednisolone; Vincristine

1983
High-performance liquid chromatographic assay for cytosine arabinoside, uracil arabinoside and some related nucleosides.
    Journal of chromatography, 1983, May-13, Volume: 274

    Topics: Arabinofuranosyluracil; Child; Chromatography, High Pressure Liquid; Cytarabine; Cytidine; Deoxycytidine; Humans; Infusions, Parenteral; Kinetics; Leukemia, Myeloid, Acute; Uridine

1983
[Chemotherapeutic approach to acute myeloid leukemia in adults].
    L'union medicale du Canada, 1983, Volume: 112, Issue:5

    Topics: Adult; Antibiotics, Antineoplastic; Antineoplastic Agents; Cytarabine; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Naphthacenes

1983
[Early phase II study of PL-AC [N4-palmitoyl-(1-beta-D-arabinofuranosyl) cytosine] on hematopoietic malignancies].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1983, Volume: 10, Issue:2 Pt

    Topics: Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Agents; Child; Cytarabine; Drug Evaluation; Female; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged

1983
Remission of acute myelogenous leukemia in elderly patients with prior refractory dysmyelopoietic anemia.
    Cancer, 1983, Sep-15, Volume: 52, Issue:6

    Topics: Age Factors; Aged; Anemia, Hemolytic; Bone Marrow; Cytarabine; Doxorubicin; Drug Therapy, Combination; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Pancytopenia; Thioguanine

1983
Cytosine arabinoside induced liver damage: histopathologic demonstration.
    Medical and pediatric oncology, 1983, Volume: 11, Issue:4

    Topics: Adult; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Liver; Middle Aged

1983
[Reduced dosage of cytosine arabinoside in the treatment of acute myelocytic leukemia. Apropos of 3 cases].
    Schweizerische medizinische Wochenschrift, 1983, Jul-12, Volume: 113, Issue:27-28

    Topics: Aged; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male

1983
Potentiation of 1-beta-D-arabinofuranosylcytosine metabolism and cytotoxicity by 2,3-dihydro-1H-imidazolo[1,2-b]pyrazole in the human promyelocytic leukemic cell, HL-60.
    Cancer research, 1983, Volume: 43, Issue:11

    Topics: Antineoplastic Agents; Biological Transport; Cell Division; Cell Line; Cell Survival; Clone Cells; Cytarabine; Deoxyribonucleosides; DNA Replication; Drug Synergism; Humans; Leukemia, Myeloid, Acute; Pyrazoles

1983
Low dose arabinosyl cytosine for treatment of myelodysplastic syndromes and subacute myeloid leukemia.
    Leukemia research, 1983, Volume: 7, Issue:4

    Topics: Adult; Aged; Anemia; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Myeloproliferative Disorders; Preleukemia

1983
Quantitation of chemosensitivity in acute myelocytic leukaemia.
    British journal of cancer, 1983, Volume: 48, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Agents; Child; Child, Preschool; Colony-Forming Units Assay; Cytarabine; Dose-Response Relationship, Drug; Doxorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplastic Stem Cells; Thioguanine; Time Factors; Tumor Stem Cell Assay

1983
[Small dose of ARA-C in the treatment of an elderly patient with acute myeloblastic leukemia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1983, Volume: 10, Issue:11

    Topics: Aged; Cerebral Infarction; Cytarabine; Humans; Leukemia, Myeloid, Acute; Male; Myocardial Infarction

1983
In vitro culture of clonogenic leukaemic cells in acute myeloid leukaemia: growth pattern and drug sensitivity.
    British journal of haematology, 1983, Volume: 55, Issue:3

    Topics: Bone Marrow; Cell Survival; Cells, Cultured; Colony-Forming Units Assay; Cytarabine; Dose-Response Relationship, Drug; Doxorubicin; Humans; Leukemia, Myeloid, Acute

1983
Urinary excretion of beta-aminoisobutyrate and pseudouridine in acute and chronic myeloid leukemia.
    Journal of the National Cancer Institute, 1983, Volume: 71, Issue:5

    Topics: Adult; Aminoisobutyric Acids; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Pseudouridine; Uridine

1983
Long term follow-up of remission patients in adult acute leukemia.
    Klinische Wochenschrift, 1983, Oct-03, Volume: 61, Issue:19

    Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Female; Follow-Up Studies; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Prognosis; Time Factors; Vincristine

1983
Low-dose cytarabine therapy in hypoplastic acute leukemia.
    The New England journal of medicine, 1983, Dec-29, Volume: 309, Issue:26

    Topics: Aged; Bone Marrow; Cytarabine; Humans; Leukemia, Myeloid, Acute; Male; Pancytopenia

1983
Low doses of cytarabine in the treatment of myelodysplastic syndrome and acute myeloid leukemia.
    The New England journal of medicine, 1983, Dec-29, Volume: 309, Issue:26

    Topics: Aged; Bone Marrow Diseases; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Pancytopenia

1983
Experience with intermediate- and high-dose cytosine arabinoside in relapsed and refractory acute leukaemia.
    The Netherlands journal of medicine, 1983, Volume: 26, Issue:8

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Doxorubicin; Drug Administration Schedule; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male

1983
Graft-versus-host reaction in 3 adult leukaemia patients after transfusion of blood cell products.
    Scandinavian journal of haematology, 1983, Volume: 31, Issue:5

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Daunorubicin; Graft vs Host Disease; Humans; Leukemia, Myeloid, Acute; Leukocytes; Male; Methotrexate; Middle Aged; Neutropenia; Prednisolone; Prednisone; Thioguanine; Transfusion Reaction; Vincristine

1983
Acute myeloid leukemia in adults: experience at AIIMS.
    The Journal of the Association of Physicians of India, 1983, Volume: 31, Issue:8

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisolone; Vincristine

1983
Multivariate analysis of factors associated with invasive fungal disease during remission induction therapy for acute myelogenous leukemia.
    Cancer, 1984, Feb-01, Volume: 53, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspergillosis; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mycoses; Risk; Sepsis; Statistics as Topic; Thioguanine

1984
[Clinical studies of BH-AC-DMP in adult acute nonlymphocytic leukemia].
    Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society, 1983, Volume: 46, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisolone

1983
Effect of dose and schedule on pharmacokinetics of high-dose cytosine arabinoside in plasma and cerebrospinal fluid.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1983, Volume: 1, Issue:9

    Topics: Cytarabine; Drug Administration Schedule; Humans; Kinetics; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma

1983
[Low dose Ara-C for remission induction in aged patients with atypical nonlymphocytic leukemia and refractory anemia with excess blasts].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1983, Volume: 24, Issue:11

    Topics: Aged; Anemia, Aplastic; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

1983
Chemotherapy for acute leukemia during pregnancy. Five case reports.
    Nouvelle revue francaise d'hematologie, 1984, Volume: 26, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Doxorubicin; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Prednisone; Pregnancy; Pregnancy Complications, Neoplastic; Vinblastine; Vincristine; Vindesine

1984
Primary colonic plasmacytoma associated with acute myelogenous leukemia.
    The American journal of gastroenterology, 1984, Volume: 79, Issue:4

    Topics: Adult; Colon; Colonic Neoplasms; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Plasmacytoma; Prednisolone

1984
Low-dose Ara-C in the treatment of acute leukemia. Cytotoxicity or differentiation induction?
    Blut, 1984, Volume: 48, Issue:4

    Topics: Adult; Cell Differentiation; Colony-Forming Units Assay; Cytarabine; Cytotoxins; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myeloid, Acute; Middle Aged

1984
Low-dose cytosine-arabinoside in the treatment of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS).
    Blut, 1984, Volume: 48, Issue:4

    Topics: Adult; Aged; Bone Marrow Diseases; Bone Marrow Examination; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Polycythemia Vera

1984
[Central nervous system involvement in adult acute leukemia].
    Gan no rinsho. Japan journal of cancer clinics, 1984, Volume: 30, Issue:3

    Topics: Acute Disease; Adult; Aged; Brain Neoplasms; Combined Modality Therapy; Cytarabine; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged

1984
A stage classification for prognosis in adult acute myelogenous leukaemia based upon patients' age, bone marrow karyotype and clinical features.
    Scandinavian journal of haematology, 1984, Volume: 32, Issue:4

    Topics: Adolescent; Adult; Age Factors; Aged; Bone Marrow Cells; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Staging; Prognosis; Thioguanine

1984
High-dose cytosine arabinoside: advances in clinical pharmacology and therapeutic results.
    Australian and New Zealand journal of medicine, 1983, Volume: 13, Issue:6

    Topics: Biotransformation; Cytarabine; DNA Replication; Dose-Response Relationship, Drug; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute

1983
Clinical trial of low-dose Ara-C in the treatment of acute leukemia and myelodysplasia.
    Blut, 1984, Volume: 48, Issue:5

    Topics: Anemia, Aplastic; Blood Cell Count; Cell Differentiation; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Primary Myelofibrosis; Thrombocytopenia

1984
Macromolecular and cell cycle effects of different classes of agents inducing the maturation of human myeloblastic leukemia (ML-1) cells.
    Cancer research, 1984, Volume: 44, Issue:6

    Topics: Cell Cycle; Cell Differentiation; Cell Line; Cycloheximide; Cytarabine; Dactinomycin; Daunorubicin; DNA Replication; Humans; Kinetics; Leucine; Leukemia, Myeloid, Acute; Protein Biosynthesis; Thymidine; Transcription, Genetic; Tretinoin; Tritium; Uridine

1984
In vitro suppression of DNA synthesis by a remission induction agent and its correlation with response in adult acute leukemia.
    European journal of cancer & clinical oncology, 1984, Volume: 20, Issue:4

    Topics: Adolescent; Adult; Aged; Cells, Cultured; Cytarabine; DNA; Doxorubicin; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Thymidine; Time Factors

1984
Progressive cutaneous herpes simplex infection in acute myeloblastic leukemia. Successful treatment with interferon and cytarabine.
    Archives of dermatology, 1984, Volume: 120, Issue:7

    Topics: Acute Disease; Adult; Appendectomy; Appendicitis; Cytarabine; Drug Therapy, Combination; Herpes Simplex; Humans; Interferon Type I; Leukemia, Myeloid, Acute; Male; Skin; Skin Diseases, Infectious; Surgical Wound Infection

1984
Low dose cytosine arabinoside: partial remission of acute myeloid leukaemia without evidence of differentiation induction.
    British journal of haematology, 1984, Volume: 57, Issue:2

    Topics: Adult; Aged; Animals; Cell Count; Cell Differentiation; Cell Line; Cells, Cultured; Clone Cells; Cytarabine; Female; Humans; Injections, Subcutaneous; Leukemia, Experimental; Leukemia, Myeloid, Acute; Male; Middle Aged

1984
Relationships among Ara-CTP pools, formation of (Ara-C)DNA, and cytotoxicity of human leukemic cells.
    Blood, 1984, Volume: 64, Issue:1

    Topics: Arabinofuranosylcytosine Triphosphate; Cell Survival; Cytarabine; DNA; Humans; Leukemia, Myeloid, Acute; Tumor Stem Cell Assay

1984
[Combination chemotherapy of N(4)-behenoyl-1-beta-arabinofuranosylcytosine, aclarubicin, 6-MP, and prednisolone (BH-AC. AMP therapy) for adult acute non-lymphocytic leukemia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:7

    Topics: Aclarubicin; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Naphthacenes; Prednisolone

1984
Acute myelogenous leukemia in pregnancy.
    Southern medical journal, 1984, Volume: 77, Issue:8

    Topics: Adult; Cesarean Section; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Infant, Newborn; Leukemia, Myeloid, Acute; Pregnancy; Pregnancy Complications, Neoplastic; Recurrence

1984
High-dose cytarabine for high blast counts.
    Annals of internal medicine, 1984, Volume: 101, Issue:3

    Topics: Aged; Cytarabine; Humans; Leukemia, Myeloid, Acute; Leukocyte Count; Male

1984
Successful remission induction in acute myelomonocytic leukaemia using low-dose cytosine arabinoside following failure of intensive chemotherapy.
    British journal of haematology, 1984, Volume: 58, Issue:1

    Topics: Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Middle Aged

1984
Prediction of response to chemotherapy in acute leukemia by in vitro drug sensitivity testing on leukemic stem cells.
    Cancer research, 1984, Volume: 44, Issue:10

    Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cell Survival; Cells, Cultured; Colony-Forming Units Assay; Cytarabine; Daunorubicin; DNA Replication; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisolone; Thioguanine

1984
Oral complications in adult leukemic patients undergoing chemotherapy.
    Dental hygiene, 1984, Volume: 58, Issue:8

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Cytarabine; Humans; Leukemia, Myeloid, Acute; Middle Aged; Mouth Diseases; Naphthacenes

1984
Induction of terminal differentiation in human K562 erythroleukemia cells by arabinofuranosylcytosine.
    The Journal of clinical investigation, 1984, Volume: 74, Issue:3

    Topics: Cell Differentiation; Cell Division; Cell Line; Cell Survival; Clone Cells; Cytarabine; Heme; Hemoglobins; Humans; Hydroxyurea; Kinetics; Leukemia, Myeloid, Acute

1984
[Treatment of adult acute promyelocytic leukemia during the period of 1974-1982].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1984, Volume: 25, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Deoxycytidine Monophosphate; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisolone

1984
[Differentiation induction of leukemic cells in acute myeloid leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1984, Volume: 25, Issue:2

    Topics: Anemia, Aplastic; Cell Differentiation; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Leukocytes; Male; Middle Aged; Prednisolone

1984
[A case of refractory acute myeloblastic leukemia who achieved partial remission by high dose cytosine arabinoside].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1984, Volume: 25, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisolone; Vincristine

1984
Acute leukaemia in a defined geographic area--incidence, clinical history and prognosis.
    Scandinavian journal of haematology, 1984, Volume: 33, Issue:2

    Topics: Adolescent; Adult; Age Factors; Aged; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisolone; Preleukemia; Sweden; Thioguanine; Vincristine

1984
[Differential cell growth inhibition and terminal differentiation induction by chemotherapeutic agents of a human acute myelogenous leukemia cell line (HL-60) in vitro].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:8

    Topics: Anthraquinones; Antineoplastic Agents; Cell Differentiation; Cell Division; Cell Line; Cell Survival; Cytarabine; Dactinomycin; Daunorubicin; Doxorubicin; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Phagocytes; Thioguanine; Vincristine

1984
Bronchopleural fistula followed by massive fatal hemoptysis in a patient with pulmonary mucormycosis. A case report.
    Archives of internal medicine, 1983, Volume: 143, Issue:5

    Topics: Adult; Bronchial Fistula; Bronchoscopy; Cytarabine; Hemoptysis; Humans; Leukemia, Myeloid, Acute; Male; Mucormycosis; Pneumonia; Pulmonary Edema; Radiography

1983
Non-cardiotoxic anthracycline regimens in the treatment of acute myeloblastic leukaemia.
    British journal of haematology, 1984, Volume: 58, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Thioguanine

1984
Thrombin generation in acute promyelocytic leukemia.
    Blood, 1984, Volume: 64, Issue:4

    Topics: Adult; Cytarabine; Disseminated Intravascular Coagulation; Doxorubicin; Female; Fibrinopeptide A; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisolone; Thrombin; Vincristine

1984
Effect of the interval between exposures to cytarabine on its cytotoxic action on HL-60 myeloid leukemic cells.
    Cancer treatment reports, 1984, Volume: 68, Issue:9

    Topics: Cell Line; Cytarabine; DNA, Neoplasm; Drug Administration Schedule; Flow Cytometry; Humans; Leukemia, Myeloid, Acute; Thymidine; Tumor Stem Cell Assay

1984
[Double minute chromosomes (DMs) in a case of acute myelocytic leukemia (M2: FAB classification)].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1984, Volume: 25, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Prednisolone; Vincristine

1984
[Analysis of the effect of cellular morphology on obtaining a complete remission in 99 cases of acute leukemia].
    Sangre, 1984, Volume: 29, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Lymphocytes; Middle Aged; Platelet Count; Prognosis

1984
Treatment of myeloblastic sarcoma in the sacral canal with high-dose cytosine arabinoside.
    Cancer chemotherapy and pharmacology, 1984, Volume: 13, Issue:3

    Topics: Cytarabine; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Sacrum

1984
[Results of treatment with 2 chemotherapeutic protocols (TAPA and VAPA) in acute myeloblastic leukemia].
    Gaceta medica de Mexico, 1984, Volume: 120, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Doxorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisolone; Prednisone; Thioguanine; Vincristine

1984
Cell differentiation and therapeutic effect of low doses of cytosine arabinoside in human myeloid leukemia.
    Leukemia research, 1984, Volume: 8, Issue:5

    Topics: Aged; Cell Differentiation; Cells, Cultured; Cytarabine; Female; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male

1984
Low-dose cytarabine in acute myeloid leukaemia.
    The Medical journal of Australia, 1984, Nov-10, Volume: 141, Issue:10

    Topics: Adult; Aged; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

1984
Experimental approaches to outcome prediction in acute myeloblastic leukemia.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1984, Volume: 94

    Topics: Cell Differentiation; Cell Division; Cell Survival; Cells, Cultured; Clone Cells; Colony-Forming Units Assay; Culture Techniques; Cytarabine; Humans; Leukemia, Myeloid, Acute; Prognosis; Time Factors; Tumor Stem Cell Assay

1984
[Low-dose cytosine arabinoside in the treatment of myeloblastic leukemia].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1984, Sep-25, Volume: 73, Issue:39

    Topics: Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid, Acute

1984
Reversible hepatotoxicity related to amphotericin B.
    Canadian Medical Association journal, 1984, Nov-15, Volume: 131, Issue:10

    Topics: Amphotericin B; Chemical and Drug Induced Liver Injury; Cytarabine; Humans; Leukemia, Myeloid, Acute; Liver; Male; Middle Aged; Mycoses; Pneumonia; Thioguanine

1984
Bone marrow fibre content in acute myeloid leukaemia before and after treatment.
    Journal of clinical pathology, 1984, Volume: 37, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Collagen; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Podophyllotoxin; Primary Myelofibrosis; Reticulin; Thioguanine

1984
Vitamin A and/or high-dose Ara-C in the maintenance of remission in acute myelogenous leukaemia in children?
    Scandinavian journal of haematology, 1984, Volume: 33, Issue:3

    Topics: Child; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid, Acute; Vitamin A

1984
Bone marrow stromal deficiency in acute myeloid leukemia in mice.
    Leukemia research, 1984, Volume: 8, Issue:6

    Topics: Animals; Bone Marrow; Culture Media; Cytarabine; Fibroblasts; Hematopoietic Stem Cells; Leukemia, Myeloid, Acute; Male; Mice; Mice, Inbred C57BL

1984
Cell kinetic studies after high dose Ara-C and adriamycin treatment in a slowly growing rat leukemia model (BNML) for human acute myelocytic leukemia.
    Leukemia research, 1984, Volume: 8, Issue:6

    Topics: Animals; Cell Cycle; Cytarabine; Disease Models, Animal; Doxorubicin; Female; Flow Cytometry; Humans; Leukemia, Myeloid, Acute; Rats; Rats, Inbred BN

1984
Enhanced tumor load reduction after chemotherapy induced recruitment and synchronization in a slowly growing rat leukemia model (BNML) for human acute myelocytic leukemia.
    Leukemia research, 1984, Volume: 8, Issue:6

    Topics: Animals; Cell Cycle; Cytarabine; Doxorubicin; Hematopoietic Stem Cells; Leukemia, Myeloid, Acute; Mice; Mice, Inbred Strains; Neoplastic Stem Cells; Rats; Rats, Inbred BN

1984
[Low-dose cytosine arabinoside treatment in acute myeloid leukemia].
    Ugeskrift for laeger, 1984, Aug-27, Volume: 146, Issue:35

    Topics: Aged; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

1984
Treatment of acute non-lymphocytic leukemia with DCMP intensive chemotherapy.
    Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society, 1984, Volume: 47, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisolone

1984
[Small-dose cytarabine (Ara-C) in the treatment of myelodysplastic syndrome].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1984, Volume: 25, Issue:10

    Topics: Anemia, Aplastic; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Preleukemia

1984
[Low-dose cytosine arabinoside (ARA-C) in the treatment of acute myeloid leukemia].
    Schweizerische medizinische Wochenschrift, 1984, Dec-01, Volume: 114, Issue:48

    Topics: Adult; Aged; Cytarabine; Drug Administration Schedule; Female; Humans; Injections, Subcutaneous; Leukemia, Myeloid, Acute; Male; Middle Aged

1984
Phase I and early phase II study of PL-AC [N4-palmitoyl-(1-beta-D-arabinofuranosyl) cytosine] on hematopoietic malignancies.
    Nihon Gan Chiryo Gakkai shi, 1984, Feb-20, Volume: 19, Issue:1

    Topics: Adolescent; Adult; Child; Cytarabine; Drug Administration Schedule; Drug Evaluation; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma; Male; Middle Aged

1984
Treatment of acute myelogenous leukemia in aged patients with low-dose Ara-C (arabinosyl cytosine).
    Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association, 1984, Volume: 83, Issue:11

    Topics: Aged; Cytarabine; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

1984
[Possibilities for the cure of acute myeloblastic leukemia with the modified VAPA regimen: preliminary results].
    Medicina clinica, 1984, Dec-08, Volume: 83, Issue:19

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Doxorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisolone; Prognosis; Vincristine

1984
A non-clonogenic assay for the determination of the sensitivity of leukemic cells to chemotherapeutic agents.
    European journal of cancer & clinical oncology, 1983, Volume: 19, Issue:11

    Topics: Aclarubicin; Aminoacridines; Amsacrine; Antineoplastic Agents; Bone Marrow; Cell Division; Cell Survival; Cells, Cultured; Colony-Stimulating Factors; Cytarabine; Doxorubicin; Humans; Leukemia, Myeloid, Acute; Methods; Naphthacenes; Thymidine; Tumor Stem Cell Assay

1983
High-dose cytosine arabinoside: clinical response to therapy in acute leukemia.
    Medical and pediatric oncology, 1982, Volume: 10 Suppl 1

    Topics: Adolescent; Adult; Aged; Bone Marrow Transplantation; Child; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged

1982
Life-threatening hypophosphatemia in a patient with acute myelogenous leukemia.
    Acta haematologica, 1980, Volume: 64, Issue:2

    Topics: Acetazolamide; Cytarabine; Daunorubicin; Female; Glucose; Humans; Leukemia, Myeloid, Acute; Middle Aged; Phosphates; Sepsis; Sodium Chloride; Starvation

1980
An unusual case of acute leukaemia.
    Haematologica, 1981, Volume: 66, Issue:4

    Topics: Antineoplastic Agents; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Middle Aged; Thioguanine; Vincristine

1981
Hypoparathyroidism and hypocalcaemia during treatment for acute leukaemia.
    British medical journal (Clinical research ed.), 1982, Mar-06, Volume: 284, Issue:6317

    Topics: Adolescent; Adult; Aged; Child; Cytarabine; Doxorubicin; Female; Humans; Hypocalcemia; Hypoparathyroidism; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Magnesium; Male; Middle Aged; Parathyroid Hormone

1982
Retrospective analysis of treatment of acute myeloblastic leukemia in patients more than 55 years old.
    Acta haematologica, 1982, Volume: 67, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents; Child; Child, Preschool; Cytarabine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Retrospective Studies; Thioguanine

1982
Induction of differentiation of human myeloid leukemia cells by inhibitors of DNA synthesis.
    Experimental hematology, 1982, Volume: 10, Issue:9

    Topics: Aphidicolin; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Cytarabine; Depression, Chemical; Diterpenes; DNA; DNA-Directed DNA Polymerase; Humans; Leukemia, Myeloid, Acute; Nucleosides

1982
[Treatment of acute myeloid leukemia with a protocol combining intensive induction chemotherapy, early consolidation treatment, splenectomy and long-term maintenance chemotherapy. Preliminary study].
    La Nouvelle presse medicale, 1982, Dec-25, Volume: 11, Issue:52

    Topics: Adolescent; Adult; Antineoplastic Agents; Child; Cytarabine; Dose-Response Relationship, Drug; Doxorubicin; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Long-Term Care; Middle Aged; Pancytopenia; Prognosis; Splenectomy; Vincristine

1982
[Acute leukaemia during pregnancy: favourable course of pregnancy in two patients treated with cytosine arabinoside and anthracyclines (author's transl)].
    La Nouvelle presse medicale, 1980, Jan-12, Volume: 9, Issue:3

    Topics: Adult; Antineoplastic Agents; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Fetus; Humans; Infant, Newborn; Leukemia, Myeloid, Acute; Male; Pregnancy; Pregnancy Complications; Remission, Spontaneous; Risk; Vincristine

1980
Cytarabine-induced anaphylaxis. Demonstration of antibody and successful desensitization.
    Archives of internal medicine, 1980, Volume: 140, Issue:3

    Topics: Aged; Anaphylaxis; Cytarabine; Desensitization, Immunologic; Drug Hypersensitivity; Humans; Leukemia, Myeloid, Acute; Male

1980
The efficiency of strict reverse isolation and antimicrobial decontamination in remission induction therapy of acute leukemia.
    Blut, 1980, Volume: 40, Issue:3

    Topics: Acute Disease; Adult; Cytarabine; Daunorubicin; Decontamination; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Patient Isolation; Retrospective Studies

1980
Myeloblastic leukemia and leukemic meningitis in a dog.
    Modern veterinary practice, 1980, Volume: 61, Issue:1

    Topics: Animals; Cytarabine; Dog Diseases; Dogs; Female; Leukemia; Leukemia, Myeloid, Acute; Meningitis; Thioguanine

1980
High rate of long-term survivals in AML treated by chemotherapy and androgenotherapy: a pilot study.
    Cancer, 1980, Apr-01, Volume: 45, Issue:7

    Topics: Adolescent; Adult; Antineoplastic Agents; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisone; Stanozolol; Vincristine; Virilism

1980
Acute myeloblastic leukemia in elderly patients: treatment and prognostic factors.
    Cancer, 1980, Jun-01, Volume: 45, Issue:11

    Topics: Aged; Aldehydes; Cytarabine; Daunorubicin; Female; Humans; Infections; Infusions, Parenteral; Injections, Intravenous; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Prognosis; Pyruvaldehyde; Sex Factors

1980
Predicting response to combination chemotherapy in acute myeloblastic leukemia--- a way to individualize treatment.
    Acta medica Scandinavica, 1980, Volume: 207, Issue:4

    Topics: Antineoplastic Agents; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute

1980
Treatment of acute myelogenous leukemia in children and adults.
    The New England journal of medicine, 1980, Aug-28, Volume: 303, Issue:9

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Blood Transfusion; Child; Child, Preschool; Cytarabine; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Granulocytes; Humans; Infant; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Methylprednisolone; Middle Aged; Vincristine

1980
[Study of the blast cell sensitivity to cytostatic agents in acute leukemia by the radioisotope method].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1980, Apr-14, Volume: 35, Issue:15

    Topics: Adolescent; Adult; Asparaginase; Bone Marrow; Cytarabine; DNA, Neoplasm; Female; Glucocorticoids; Humans; Hydrocortisone; In Vitro Techniques; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphocytes; Male; Middle Aged; Vincristine

1980
Lithium and granulocytopenia during induction therapy of acute myelogenous leukemia: update of an ongoing trial.
    Advances in experimental medicine and biology, 1980, Volume: 127

    Topics: Agranulocytosis; Bacterial Infections; Cytarabine; Daunorubicin; Fever; Humans; Leukemia, Myeloid, Acute; Lithium; Middle Aged; Neutropenia; Thrombocytopenia; Time Factors

1980
A seven year laboratory and clinical experience with lithium carbonate as an adjuvant to cancer chemotherapy.
    Advances in experimental medicine and biology, 1980, Volume: 127

    Topics: Bone Marrow Cells; Cells, Cultured; Cytarabine; Daunorubicin; Drug Therapy, Combination; Granulocytes; Humans; Leukemia, Myeloid, Acute; Leukocytosis; Lithium; Lymphoma, Non-Hodgkin; Methotrexate

1980
Prediction of response to chemotherapy in acute myelocytic leukemia.
    Blood, 1980, Volume: 56, Issue:3

    Topics: Adolescent; Adult; Aged; Bone Marrow Cells; Cell Division; Child; Clone Cells; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis

1980
Acute promyelocytic leukemia--clinical management of 15 patients.
    American journal of hematology, 1980, Volume: 8, Issue:4

    Topics: Adolescent; Adult; Aged; Cytarabine; Daunorubicin; Disseminated Intravascular Coagulation; Doxorubicin; Female; Heparin; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

1980
Posttransfusion hepatitis in acute myelogenous leukemia. Effect on survival.
    JAMA, 1980, Oct-17, Volume: 244, Issue:16

    Topics: Adolescent; Adult; Aspartate Aminotransferases; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Hepatitis B; Humans; Infant; Leukemia, Myeloid, Acute; Liver Function Tests; Male; Middle Aged; Prognosis; Retrospective Studies; Thioguanine

1980
[Cytosine arabinoside in the treatment of herpes simplex and chickenpox].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1980, Jun-15, Volume: 33, Issue:12

    Topics: Chickenpox; Child; Cytarabine; Herpes Simplex; Humans; Infant, Newborn; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute

1980
Treatment of psoriasis with daunorubicin and cytarabine.
    Archives of dermatology, 1980, Volume: 116, Issue:10

    Topics: Aged; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Psoriasis

1980
Sensitivity of normal and acute myelogenous leukaemia marrow cells to inhibition by cytosine arabinoside.
    British journal of cancer, 1980, Volume: 41, Issue:6

    Topics: Bone Marrow; Cells, Cultured; Cytarabine; DNA; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid, Acute

1980
Variation in sensitivity of DNA synthesis to ara-C in acute myeloid leukaemia.
    British journal of haematology, 1980, Volume: 45, Issue:3

    Topics: Arabinofuranosylcytosine Triphosphate; Bone Marrow; Cells, Cultured; Cytarabine; DNA, Neoplasm; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid, Acute

1980
Selective use of daunorubicin for remission-induction chemotherapy in acute non-lymphoblastic leukemia.
    Cancer, 1980, Oct-15, Volume: 46, Issue:8

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission, Spontaneous; Thioguanine

1980
[Results of treatment of exacerbation of myelocytic leukemia according to the TRAMPCO program].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1980, Jul-14, Volume: 35, Issue:28

    Topics: Adult; Aged; Asparaginase; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Prednisone; Thioguanine; Vincristine

1980
[Results of complex treatment of adults with myeloblastic leukemia].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1980, Aug-04, Volume: 35, Issue:31

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisone; Vincristine

1980
Acute leukemia during pregnancy.
    Southern medical journal, 1980, Volume: 73, Issue:10

    Topics: Adult; Cytarabine; Drug Administration Schedule; Female; Humans; Infant, Newborn; Leukemia, Myeloid, Acute; Pregnancy; Pregnancy Complications, Hematologic; Pregnancy Trimester, Second; Thioguanine

1980
Cytokinetic changes in the peripheral blood of leukemic patients during cytostatic therapy. VI. Effect of arabinosylcytosine.
    Basic and applied histochemistry, 1980, Volume: 24, Issue:4

    Topics: Adult; Aged; Blood Cells; Cytarabine; DNA; Female; Humans; Interphase; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Primary Myelofibrosis

1980
[Treatment of acute myeloblastic leukemia by the combination of daunorubicin (or rubidazone) and cytosine arabinoside (apropos of 76 cases)].
    Lille medical : journal de la Faculte de medecine et de pharmacie de l'Universite de Lille, 1980, Volume: 25, Issue:10

    Topics: Acute Disease; Adult; Antineoplastic Agents; Cytarabine; Daunorubicin; Drug Therapy, Combination; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Middle Aged

1980
Absence of the influence of age on remission rate and duration of remission in a group of thirty-four patients with acute myeloid leukaemia.
    The Netherlands journal of medicine, 1980, Volume: 23, Issue:6

    Topics: Adult; Age Factors; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Thioguanine

1980
Quantitation of 1-beta-D-arabinofuranosylcytosine 5'-triphosphate in the leukemic cells from bone marrow and peripheral blood of patients receiving 1-beta-D-arabinofuranosylcytosine therapy.
    Cancer research, 1980, Volume: 40, Issue:3

    Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Bone Marrow; Cytarabine; Humans; Leukemia, Myeloid, Acute; Lymphocytes

1980
Blast colony formation in myelogenous leukemia: drug sensitivity and renewal capacity of the leukemic clone.
    Progress in clinical and biological research, 1980, Volume: 48

    Topics: Antineoplastic Agents; Cell Division; Cell Survival; Clone Cells; Cytarabine; Doxorubicin; Drug Evaluation; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Methylcellulose; Phytohemagglutinins

1980
Simultaneous determination of 1-beta-D-arabinofuranosylcytosine 5'-triphosphate and 3-deazauridine 5'-triphosphate in human leukemia cells by high-performance liquid chromatography.
    Journal of chromatography, 1980, Dec-12, Volume: 221, Issue:2

    Topics: 3-Deazauridine; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cells, Cultured; Chromatography, High Pressure Liquid; Cytarabine; Cytidine Triphosphate; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Uracil Nucleotides; Uridine; Uridine Triphosphate

1980
Acute leukemia: early recognition can spell survival.
    Geriatrics, 1981, Volume: 36, Issue:6

    Topics: Aged; Antibiotics, Antineoplastic; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence

1981
Re-induction of complete remissions in adults with acute non-lymphocytic leukemia.
    Leukemia research, 1981, Volume: 5, Issue:1

    Topics: Cytarabine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Thioguanine

1981
The heritable nature of clonal characteristics in acute myeloblastic leukemia.
    Blood, 1981, Volume: 58, Issue:1

    Topics: Clone Cells; Colony-Forming Units Assay; Cytarabine; Doxorubicin; Drug Resistance; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute

1981
Cytosine arabinoside deamination in human leukaemic myeloblasts and resistance to cytosine arabinoside therapy.
    Clinical science (London, England : 1979), 1981, Volume: 60, Issue:2

    Topics: Adult; Arabinofuranosylcytosine Triphosphate; Arabinofuranosyluracil; Bone Marrow; Cells, Cultured; Cytarabine; Deamination; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Resistance; Humans; Leukemia, Myeloid, Acute; Tetrahydrouridine

1981
[The trials of determination of acute leukemia blasts sensitivity against cytostatics (author's transl)].
    Przeglad lekarski, 1981, Volume: 38, Issue:2

    Topics: Adult; Antineoplastic Agents; Asparaginase; Cells, Cultured; Cytarabine; Daunorubicin; Drug Evaluation, Preclinical; Humans; In Vitro Techniques; Leukemia, Myeloid, Acute; Lymphocytes; Methotrexate; Middle Aged; Vincristine

1981
1-beta-D-arabinofuranosylcytosine (ara-C) deamination in human leukemic myeloblasts is not a mechanism of resistance to ara-C therapy.
    Cancer research, 1981, Volume: 41, Issue:7

    Topics: Bone Marrow; Cells, Cultured; Cytarabine; Deamination; Humans; Leukemia, Myeloid, Acute; Tetrahydrouridine

1981
Lethality of human myeloblasts correlates with the incorporation of arabinofuranosylcytosine into DNA.
    Proceedings of the National Academy of Sciences of the United States of America, 1981, Volume: 78, Issue:5

    Topics: Cell Division; Cell Line; Cell Survival; Cells, Cultured; Clone Cells; Cytarabine; DNA Replication; Humans; Leukemia, Myeloid, Acute

1981
Intensive chemotherapy is the treatment of choice for elderly patients with acute myelogenous leukemia.
    Blood, 1981, Volume: 58, Issue:3

    Topics: Adolescent; Adult; Aged; Cytarabine; Daunorubicin; Female; Granulocytes; Humans; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Platelet Count; Platelet Transfusion; Thioguanine; Time Factors

1981
Treatment of patients over 50 years of age with acute myelogenous leukemia with a combination of rubidazone and cytosine arabinoside, vincristine, and prednisone (ROAP).
    Blood, 1981, Volume: 58, Issue:3

    Topics: Aged; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Drug Therapy, Combination; Female; Hematologic Diseases; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Pneumonia; Prednisone; Sepsis; Time Factors; Vincristine

1981
Long chemotherapy-free remissions after single-cycle timed-sequential chemotherapy for acute myelocytic leukemia.
    Cancer, 1980, Mar-01, Volume: 45, Issue:5

    Topics: Adolescent; Adult; Aged; Bone Marrow; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Middle Aged

1980
A four-year experience with anthracycline, cytosine arabinoside, vincristine and prednisone combination chemotherapy in 325 adults with acute leukemia.
    Cancer, 1981, Jun-15, Volume: 47, Issue:12

    Topics: Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Cytarabine; Drug Administration Schedule; Drug Therapy, Combination; Female; Glycosides; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Naphthacenes; Prednisone; Vincristine

1981
Double minute chromosomes in a case of acute myelogenous leukemia resistant to chemotherapy.
    Cytogenetics and cell genetics, 1981, Volume: 30, Issue:1

    Topics: Aged; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Daunorubicin; Female; Humans; Karyotyping; Leukemia, Myeloid, Acute

1981
Acute myeloblastic leukemia presenting as progressive hepatic failure.
    Southern medical journal, 1981, Volume: 74, Issue:8

    Topics: Adult; Child, Preschool; Cytarabine; Humans; Leukemia, Myeloid, Acute; Liver Diseases; Male

1981
[Case of full remission of a blast crisis in myelocytic leukemia].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1981, Mar-15, Volume: 34, Issue:6

    Topics: Blood Transfusion; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Middle Aged; Prednisone; Remission, Spontaneous

1981
Graft-versus-host disease in consecutive patients with acute myeloid leukaemia treated with blood cells from normal donors.
    Australian and New Zealand journal of medicine, 1981, Volume: 11, Issue:2

    Topics: Cytarabine; Doxorubicin; Graft vs Host Reaction; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Transfusion Reaction; Transplantation Immunology

1981
[Treatment of acute non-lymphocytic leukemia with concurrent administration of N4-behenoyl-beta-D-arabinofuranosylcytosine, aclacinomycin A, 6-mercaptopurine and prednisolone; a pilot study (author's transl)].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1981, Volume: 22, Issue:3

    Topics: Aclarubicin; Adult; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Naphthacenes; Prednisolone

1981
Chemotherapy of leukemia in mice, rats, and humans relating time of humoral stimulation, tumor growth, and clinical response.
    Journal of the National Cancer Institute, 1981, Volume: 67, Issue:3

    Topics: Animals; Cell Division; Cytarabine; Daunorubicin; DNA, Neoplasm; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia L1210; Leukemia, Experimental; Leukemia, Myeloid, Acute; Mice; Rats

1981
Bone marrow biopsy.
    The American journal of surgical pathology, 1981, Volume: 5, Issue:5

    Topics: Bone Marrow; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute

1981
DNA damage in AML cell exposed to adriamycin; correlations with clinical response to therapy.
    Leukemia research, 1981, Volume: 5, Issue:4-5

    Topics: Cells, Cultured; Cytarabine; DNA Repair; DNA, Neoplasm; Doxorubicin; Drug Evaluation, Preclinical; Drug Resistance; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Prognosis

1981
The pharmacokinetics of subcutaneous cytosine arabinoside in patients with acute myelogenous leukaemia.
    British journal of clinical pharmacology, 1981, Volume: 12, Issue:4

    Topics: Adult; Cytarabine; Drug Administration Schedule; Humans; Infusions, Parenteral; Injections, Intravenous; Injections, Subcutaneous; Kinetics; Leukemia, Myeloid, Acute

1981
Eastern Cooperative Oncology Group study of the cytochemistry of adult acute myeloid leukemia by correlation of subtypes with response and survival.
    Cancer research, 1981, Volume: 41, Issue:11 Pt 2

    Topics: Adult; Cytarabine; Daunorubicin; Histocytochemistry; Humans; Leukemia, Myeloid, Acute; Nervous System Neoplasms; Prognosis; Thioguanine; Vincristine

1981
Self-renewal capacity of leukemic blast progenitor cells.
    Cancer research, 1981, Volume: 41, Issue:11 Pt 2

    Topics: Aminoacridines; Amsacrine; Cell Division; Clone Cells; Cytarabine; Dose-Response Relationship, Drug; Doxorubicin; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Prognosis

1981
Dose-dependent suppression of DNA synthesis in vitro as a predictor of clinical response in adult acute myeloblastic leukemia.
    European journal of cancer, 1981, Volume: 17, Issue:5

    Topics: Adolescent; Adult; Aged; Cells, Cultured; Cytarabine; Depression, Chemical; DNA, Neoplasm; Dose-Response Relationship, Drug; Doxorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Thymidine

1981
Effects of cytosine arabinoside on DNA synthesis as predictor for acute myelocytic leukemia (AML) patients' response to chemotherapy.
    European journal of cancer, 1981, Volume: 17, Issue:6

    Topics: Bone Marrow; Cells, Cultured; Colony-Forming Units Assay; Cytarabine; Daunorubicin; DNA, Neoplasm; Doxorubicin; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Thymidine

1981
VAPA10: a treatment program for acute myelocytic leukemia.
    Haematology and blood transfusion, 1981, Volume: 26

    Topics: Adolescent; Adult; Age Factors; Antineoplastic Agents; Child; Child, Preschool; Cytarabine; Doxorubicin; Drug Therapy, Combination; Humans; Infant; Leukemia, Myeloid, Acute; Middle Aged; Prednisolone; Probability; Recurrence; Vincristine

1981
Leukemic infiltration of the cerebellum in acute myelomonocytic leukemia.
    Neurology, 1982, Volume: 32, Issue:1

    Topics: Adult; Cerebellar Ataxia; Cerebellar Neoplasms; Cerebellum; Cytarabine; Drug Therapy, Combination; Female; Humans; Injections, Intraventricular; Leukemia, Myeloid, Acute; Methotrexate; Neoplasm Recurrence, Local; Tomography, X-Ray Computed

1982
Cytosine arabinoside influx and nucleoside transport sites in acute leukemia.
    The Journal of clinical investigation, 1982, Volume: 69, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Aged; Binding Sites; Bone Marrow Cells; Carrier Proteins; Cell Transformation, Neoplastic; Child; Child, Preschool; Cytarabine; Humans; Infant; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Middle Aged; Nucleosides; Thioinosine; Time Factors

1982
[Remission induction by ACM-A and BH-AC on acute promyelocytic leukemia which is resistant to DNR and CA (author's transl)].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1981, Volume: 22, Issue:7

    Topics: Aclarubicin; Adult; Cytarabine; Daunorubicin; Drug Resistance; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Male; Naphthacenes

1981
The contribution of blast cell properties to outcome variation in acute myeloblastic leukemia (AML).
    Blood, 1982, Volume: 59, Issue:3

    Topics: Analysis of Variance; Cell Transformation, Neoplastic; Cells, Cultured; Cytarabine; Doxorubicin; Humans; Leukemia, Myeloid, Acute; Middle Aged; Regression Analysis; Risk

1982
A pilot study of high-dose 1-beta-D-arabinofuranosylcytosine for acute leukemia and refractory lymphoma: clinical response and pharmacology.
    Cancer research, 1982, Volume: 42, Issue:4

    Topics: Adolescent; Adult; Aged; Blood; Bone Marrow; Brain; Brain Neoplasms; Child; Cytarabine; Drug Evaluation; Eye; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma; Male; Middle Aged; Pilot Projects

1982
Treatment of relapsed acute myelocytic leukemia with a combination of aclarubicin and cytosine arabinoside.
    Acta medica Okayama, 1982, Volume: 36, Issue:1

    Topics: Aclarubicin; Antineoplastic Agents; Cytarabine; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Naphthacenes; Recurrence

1982
Small doses of ARA-C in the treatment of acute myeloid leukaemia: differentiation of myeloid leukaemia cells?
    British journal of haematology, 1982, Volume: 51, Issue:1

    Topics: Aged; Cell Differentiation; Cytarabine; Drug Administration Schedule; Female; Humans; Injections, Subcutaneous; Leukemia, Myeloid, Acute; Male; Middle Aged

1982
Treatment of acute myeloid leukaemia in children.
    Australian and New Zealand journal of medicine, 1982, Volume: 12, Issue:2

    Topics: Adolescent; Antineoplastic Agents; Brain Neoplasms; Child; Child, Preschool; Cytarabine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Infant; Leukemia, Myeloid, Acute; Male; Thioguanine

1982
Causes of initial remission induction failure in acute myelogenous leukemia.
    Blood, 1982, Volume: 60, Issue:2

    Topics: Adult; Antibiotics, Antineoplastic; Bacterial Infections; Cytarabine; Daunorubicin; Doxorubicin; Hemorrhage; Humans; Leukemia, Myeloid, Acute; Mycoses; Pneumonia; Prednisone; Vincristine

1982
Case report: acute leukemia after semustine (methyl-CCNU) therapy.
    Cancer treatment reports, 1982, Volume: 66, Issue:7

    Topics: Adenocarcinoma; Aged; Cecal Neoplasms; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Nitrosourea Compounds; Semustine

1982
Treatment of refractory acute leukaemia with high dose cytosine arabinoside.
    British journal of haematology, 1982, Volume: 51, Issue:3

    Topics: Adolescent; Adult; Cytarabine; Drug Administration Schedule; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged

1982
Brachial plexus neuritis and fatal hemorrhage following Aspergillus infection of a Hickman catheter.
    Cancer, 1982, Sep-15, Volume: 50, Issue:6

    Topics: Antineoplastic Agents; Aspergillosis; Brachial Plexus; Catheters, Indwelling; Cytarabine; Female; Hemorrhage; Humans; Leukemia, Myeloid, Acute; Middle Aged; Neuritis; Thioguanine

1982
Differential effect of N-(phosphonacetyl)-L-aspartate on 1-beta-D-arabinofuranosylcytosine metabolism and cytotoxicity in human leukemia and normal bone marrow progenitors.
    Cancer research, 1982, Volume: 42, Issue:10

    Topics: Antimetabolites, Antineoplastic; Aspartic Acid; Bone Marrow; Cell Line; Cells, Cultured; Cytarabine; DNA Replication; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Organophosphorus Compounds; Phosphonoacetic Acid

1982
Prognostic factors in response to anthracyclines.
    Cancer treatment reports, 1981, Volume: 65 Suppl 4

    Topics: Age Factors; Antibiotics, Antineoplastic; Body Temperature; Cytarabine; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Metaphase; Middle Aged; Naphthacenes; Precancerous Conditions; Prognosis; Prospective Studies; Regression Analysis; Retrospective Studies

1981
Vincristine and prednisolone therapy in blast crisis of chronic myelogenous leukaemia in childhood.
    Scandinavian journal of haematology, 1981, Volume: 27, Issue:5

    Topics: Adolescent; Child; Cyclophosphamide; Cytarabine; DNA Nucleotidylexotransferase; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Meningeal Neoplasms; Prednisolone; Prognosis; Vincristine

1981
Acute leukaemia in pregnancy. A case report and discussion on modern management.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1982, Aug-21, Volume: 62, Issue:9

    Topics: Adult; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Pregnancy; Pregnancy Complications, Hematologic; Thioguanine

1982
Retrospective analysis of 158 cases of adult acute leukaemia: factors influencing prognosis and treatment response.
    Australian and New Zealand journal of medicine, 1982, Volume: 12, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Karyotyping; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Middle Aged; Prednisolone; Prognosis; Regression Analysis; Retrospective Studies; Thioguanine; Vincristine

1982
Terminal differentiation of the human promyelocytic leukemia cell line, HL-60, in the absence of cell proliferation.
    Cancer research, 1982, Volume: 42, Issue:11

    Topics: Cell Cycle; Cell Differentiation; Cell Division; Cell Line; Cell Survival; Cytarabine; Dimethyl Sulfoxide; Humans; Hydroxyurea; Kinetics; Leukemia, Myeloid, Acute

1982
Improved prospects for long-term survival in adults with acute myelogenous leukemia.
    JAMA, 1982, Nov-19, Volume: 248, Issue:19

    Topics: Adolescent; Adult; Age Factors; Aged; Antibiotics, Antineoplastic; Cytarabine; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Naphthacenes; Prognosis; Time Factors

1982
High dose cytosine arabinoside in the management of refractory acute leukaemia.
    Scandinavian journal of haematology, 1982, Volume: 29, Issue:2

    Topics: Adolescent; Adult; Bone Marrow; Cell Transformation, Neoplastic; Cytarabine; Dose-Response Relationship, Drug; Doxorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged

1982
The relationship of Ara-C metabolism in vitro to therapeutic response in acute myeloid leukaemia.
    Cancer chemotherapy and pharmacology, 1982, Volume: 9, Issue:1

    Topics: Arabinofuranosyluracil; Bone Marrow Cells; Cytarabine; Cytidine Triphosphate; Deamination; Humans; Leukemia, Myeloid, Acute; Phosphorylation; Time Factors

1982
[Treatment of acute promyelocytic leukemia: comparison of the therapeutic effect of daunorubicin and "DCMP" regimen in remission induction treatment].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1982, Volume: 23, Issue:7

    Topics: Adult; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisone

1982
Totally implanted system for intravenous chemotherapy in patients with cancer.
    The American journal of medicine, 1982, Volume: 73, Issue:6

    Topics: Antineoplastic Agents; Blood Transfusion; Cytarabine; Doxorubicin; Humans; Infusions, Parenteral; Leukemia, Myeloid, Acute; Male; Middle Aged; Vena Cava, Superior; Vincristine

1982
[Treatment of acute myeloid leukemia with an intense chemotherapeutic regimen and variable reduction of the dosage for elderly patients].
    La Clinica terapeutica, 1982, Volume: 102, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Cytarabine; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Thioguanine

1982
Acute myelogenous leukemia: successful treatment of relapse with cytosine arabinoside, VP 16-213, vincristine and vinblastine (A-triple-V).
    European journal of cancer & clinical oncology, 1982, Volume: 18, Issue:8

    Topics: Adult; Aged; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Therapy, Combination; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Thrombocytopenia; Vinblastine; Vincristine

1982
Multicentre study on intensified remission induction therapy for acute myeloid leukemia.
    Leukemia research, 1982, Volume: 6, Issue:6

    Topics: Adolescent; Adult; Aged; Cytarabine; Daunorubicin; Drug Evaluation; Humans; Leukemia, Myeloid, Acute; Middle Aged; Time Factors

1982
Introduction to the symposium on high-dose cytosine arabinoside.
    Medical and pediatric oncology, 1982, Volume: 10 Suppl 1

    Topics: Cytarabine; Humans; Leukemia, Myeloid, Acute

1982
The pharmacokinetics of cytosine arabinoside in the plasma and cerebrospinal fluid during conventional and high-dose therapy.
    Medical and pediatric oncology, 1982, Volume: 10 Suppl 1

    Topics: Cytarabine; Dose-Response Relationship, Drug; Humans; Kinetics; Leukemia, Myeloid, Acute

1982
Use of cytosar in pediatric acute myelocytic leukemia and leukemic meningitis.
    Medical and pediatric oncology, 1982, Volume: 10 Suppl 1

    Topics: Age Factors; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Humans; Hydrocortisone; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Meningitis; Methotrexate

1982
A comparison of two schedules of cytosine arabinoside used in combination with adriamycin and 6-thioguanine in the treatment of acute myelogenous leukemia.
    Medical and pediatric oncology, 1982, Volume: 10 Suppl 1

    Topics: Adult; Bone Marrow; Cytarabine; Digestive System; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Leukocyte Count; Thioguanine

1982
High doses of cytosine arabinoside (HD-Ara-C) as reinforcement during remission of acute myeloid leukemia.
    Medical and pediatric oncology, 1982, Volume: 10 Suppl 1

    Topics: Adult; Cytarabine; Digestive System; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

1982
In vitro sensitivity of CFU-L to cytosine arabinoside (Ara-C).
    Medical and pediatric oncology, 1982, Volume: 10 Suppl 1

    Topics: Bone Marrow; Cells, Cultured; Cytarabine; Dose-Response Relationship, Drug; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute

1982
[Treatment of acute leukemias].
    Wiener klinische Wochenschrift, 1982, Nov-12, Volume: 94, Issue:21

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Humans; Infant; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Middle Aged; Prednisone; Prognosis; Vincristine

1982
Whether or not to administer Amphotericin to an immunosuppressed patient with hematologic malignancy and undiagnosed fever.
    Medical decision making : an international journal of the Society for Medical Decision Making, 1981, Volume: 1, Issue:1

    Topics: Agranulocytosis; Amphotericin B; Cytarabine; Daunorubicin; Decision Making; Esophagitis; Fever of Unknown Origin; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mycoses

1981
[Comparative evaluation of a combination of daunorubicin and cytosine arabinoside and that of aclarubicin and cytosine arabinoside in remission induction in acute non-lymphocytic leukemia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1982, Volume: 9, Issue:9

    Topics: Aclarubicin; Adult; Aged; Antibiotics, Antineoplastic; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Naphthacenes; Random Allocation

1982
Variations of the phosphorylation of 1-beta-D-arabinofuranosylcytosine (ARA-C) in human myeloid leukemic cells related to the cell cycle.
    Leukemia research, 1982, Volume: 6, Issue:2

    Topics: Cell Cycle; Cell Separation; Cytarabine; DNA Replication; Humans; Leukemia, Myeloid, Acute; Phosphorylation

1982
The treatment of acute myelocytic leukemia in patients 30 years of age and younger.
    American journal of hematology, 1982, Volume: 13, Issue:3

    Topics: Adolescent; Adult; Age Factors; Antineoplastic Agents; Cytarabine; Daunorubicin; Doxorubicin; Drug Combinations; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Sulfamethoxazole; Thioguanine; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1982
Fatal veno-occlusive disease of the liver following high dose chemotherapy, irradiation and bone marrow transplantation.
    The American journal of medicine, 1980, Volume: 68, Issue:2

    Topics: Antineoplastic Agents; Bone Marrow Transplantation; Burkitt Lymphoma; Child; Cytarabine; Drug Therapy, Combination; Female; Hepatic Veins; Humans; Leukemia, Myeloid, Acute; Liver; Liver Diseases; Male; Radiotherapy; Transplantation, Autologous; Transplantation, Homologous; Vascular Diseases

1980
[Effect on peripheral blood cells in children with acute leukemia during remission by intramuscular injected of arabinosyl-cytosine (author's transl)].
    Onkologie, 1980, Volume: 3, Issue:2

    Topics: Blood Cell Count; Blood Cells; Child; Cytarabine; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute

1980
Treatment of early acute nonlymphatic leukemia with low dose cytosine arabinoside.
    Haematology and blood transfusion, 1981, Volume: 26

    Topics: Adult; Aged; Animals; Bone Marrow; Bone Marrow Transplantation; Cell Division; Cytarabine; Drug Administration Schedule; Female; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Rats

1981
Blast cell proliferative activity and sensitivity to GM-CSF in vitro are associated with early response to TAD-9 induction therapy in acute myeloid leukemia.
    Leukemia, 1995, Volume: 9, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells; Cell Division; Cells, Cultured; Cytarabine; Daunorubicin; DNA Polymerase II; DNA, Neoplasm; Drug Screening Assays, Antitumor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Thioguanine

1995
Pharmacokinetics of mitoxantrone, etoposide and cytosine arabinoside in leukemic cells during treatment of acute myelogenous leukemia--relationship to treatment outcome and bone marrow toxicity.
    Leukemia research, 1995, Volume: 19, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Etoposide; Humans; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Treatment Outcome

1995
Acute nonlymphocytic leukemia complicated by Garcin's syndrome.
    Acta haematologica, 1995, Volume: 94, Issue:3

    Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cranial Nerve Neoplasms; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Magnetic Resonance Imaging; Paralysis; Prednisolone; Recurrence; Syndrome; Zinostatin

1995
[A case of acute myeloblastic leukemia invaded uterine cervix-diagnosed by changes in peripheral blood after G-CSF administration].
    Nihon Sanka Fujinka Gakkai zasshi, 1993, Volume: 45, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Cytarabine; Daunorubicin; Diagnosis, Differential; Doxorubicin; Female; Granulocyte Colony-Stimulating Factor; Granulocytes; Humans; Leukemia, Myeloid, Acute; Leukocyte Count; Mercaptopurine; Middle Aged; Neoplasm Invasiveness; Prednisolone; Prednisone; Recombinant Proteins; Uterine Cervical Neoplasms; Vincristine

1993
Combinations of stem cell factor with other hematopoietic growth factors enhance growth and sensitivity to cytosine arabinoside of blast progenitors in acute myelogenous leukemia.
    Cancer research, 1994, Jan-15, Volume: 54, Issue:2

    Topics: Adolescent; Adult; Aged; Cell Cycle; Child, Preschool; Cytarabine; Female; Hematopoietic Cell Growth Factors; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplastic Stem Cells; Stem Cell Factor; Tumor Cells, Cultured; Tumor Stem Cell Assay

1994
[Complete remission during administration of rhG-CSF in acute myeloblastic leukemia with pneumonia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1994, Volume: 35, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Pancytopenia; Pneumonia; Prednisolone; Recombinant Proteins; Remission Induction

1994
Combination of hematopoietic growth factors containing IL-3 induce acute myeloid leukemia cell sensitization to cycle specific and cycle non-specific drugs.
    Leukemia, 1994, Volume: 8, Issue:5

    Topics: Antineoplastic Agents; Cell Cycle; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Cell Growth Factors; Humans; Interleukin-3; Leukemia, Myeloid, Acute; Male; Tumor Cells, Cultured

1994
Structural analysis of the deoxycytidine kinase gene in patients with acute myeloid leukemia and resistance to cytosine arabinoside.
    Leukemia, 1994, Volume: 8, Issue:5

    Topics: Adult; Aged; Base Sequence; Blotting, Southern; Codon; Cytarabine; Deoxycytidine Kinase; DNA Mutational Analysis; Drug Resistance; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction; RNA-Directed DNA Polymerase; RNA, Neoplasm

1994
Successful second autologous blood stem cell transplantation after G-CSF-combined conditioning for the treatment of high-risk acute myelogenous leukemia.
    Bone marrow transplantation, 1994, Volume: 13, Issue:3

    Topics: Adult; Blood Transfusion, Autologous; Combined Modality Therapy; Cytarabine; DNA, Neoplasm; Drug Therapy, Combination; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Male; Recombinant Proteins; Recurrence; Remission Induction; Risk Factors; Thymidine; Tritium

1994
In vitro response of blasts to IL-3, GM-CSF, and G-CSF is different for individual AML patients: factors that stimulate leukemic clonogenic cells also enhance Ara-C cytotoxicity.
    Annals of hematology, 1994, Volume: 68, Issue:5

    Topics: Adolescent; Adult; Aged; Cell Division; Cell Survival; Cytarabine; Dose-Response Relationship, Drug; Female; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-3; Leukemia, Myeloid, Acute; Male; Middle Aged; Tumor Cells, Cultured

1994
Hematopoietic growth factor stimulation and cytarabine cytotoxicity in vitro: effects in untreated and relapsed or primary refractory acute myeloid leukemia cells.
    Leukemia, 1994, Volume: 8, Issue:9

    Topics: Adult; Aged; Bromodeoxyuridine; Cytarabine; DNA, Neoplasm; Female; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Cell Growth Factors; Humans; Interleukin-3; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Tumor Cells, Cultured; Tumor Stem Cell Assay

1994
Fludarabine + Ara-C + G-CSF: cytotoxic effect and induction of apoptosis on fresh acute myeloid leukemia cells.
    Leukemia, 1994, Volume: 8, Issue:12

    Topics: Antineoplastic Agents; Apoptosis; Bone Marrow; Cytarabine; DNA, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Tumor Cells, Cultured; Vidarabine

1994
All-trans retinoic acid potentiates megakaryocyte colony formation: in vitro and in vivo effects after administration to acute promyelocytic leukemia patients.
    Leukemia, 1994, Volume: 8, Issue:12

    Topics: Antigens, CD; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Cells; Colony-Forming Units Assay; Cytarabine; Daunorubicin; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Megakaryocytes; Tretinoin

1994
[Continuation of complete remission by oral administration of cytarabine ocfosfate in a patient with M0, who achieved remission by small doses of cytosine arabinoside with G-CSF].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1995, Volume: 36, Issue:1

    Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Remission Induction

1995
Factor VIII inhibitor prior to and during secondary acute nonlymphocytic leukemia in a patient with cured Hodgkin's disease.
    Leukemia & lymphoma, 1995, Volume: 16, Issue:5-6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Autoantibodies; Blood Transfusion; Combined Modality Therapy; Cytarabine; Factor VIII; Female; Granulocyte Colony-Stimulating Factor; Hemophilia A; Hemorrhage; Hodgkin Disease; Humans; Immunologic Factors; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Lymphatic Irradiation; Mechlorethamine; Middle Aged; Neoplasms, Second Primary; Plasmapheresis; Prednisone; Procarbazine; Prothrombin; Remission Induction; Thrombocytopenia; Vidarabine; Vincristine

1995
In vitro-induced resistance to the deoxycytidine analogues cytarabine (AraC) and 5-aza-2'-deoxycytidine (DAC) in a rat model for acute myeloid leukemia is mediated by mutations in the deoxycytidine kinase (dck) gene.
    Annals of hematology, 1995, Volume: 71, Issue:1

    Topics: Animals; Antineoplastic Agents; Azacitidine; Base Sequence; Chromosome Aberrations; Cytarabine; Decitabine; Deoxycytidine Kinase; Drug Resistance; In Situ Hybridization, Fluorescence; Leukemia, Myeloid, Acute; Molecular Sequence Data; Point Mutation; Polymorphism, Single-Stranded Conformational; Rats; Translocation, Genetic; Tumor Cells, Cultured

1995
Plasma levels of IL-1, TNF alpha, IL-6, IL-8, G-CSF, and IL1-RA during febrile neutropenia: results of a prospective study in patients undergoing chemotherapy for acute myelogenous leukemia.
    Annals of hematology, 1995, Volume: 71, Issue:4

    Topics: Adolescent; Adult; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Cytokines; Dacarbazine; Female; Fever; Granulocyte Colony-Stimulating Factor; Humans; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Interleukin-2; Interleukin-6; Interleukin-8; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Neutropenia; Nimustine; Prospective Studies; Sialoglycoproteins; Tumor Necrosis Factor-alpha; Vincristine

1995
[Plasma concentration of cytosine arabinoside (Ara-C) in the elderly patients with hematological malignancy treated by Ara-C or cytarabine ocfosfate (SPAC)].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 1995, Volume: 32, Issue:3

    Topics: Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Agents; Arabinonucleotides; Cytarabine; Cytidine Monophosphate; Female; Humans; Infusions, Intravenous; Injections, Subcutaneous; Leukemia, Myeloid, Acute; Male; Myelodysplastic Syndromes

1995
Dose-intensive treatment of acute myelogenous leukemia: improved survival?
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1995, Volume: 13, Issue:7

    Topics: Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Patient Selection; Prognosis; Remission Induction; Sex Factors

1995
Oral Fusarium infection in a granulocytopenic patient with acute myelogenous leukemia: a case report.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 1995, Volume: 24, Issue:5

    Topics: Acute Kidney Injury; Aged; Agranulocytosis; Amphotericin B; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Epirubicin; Etoposide; Fatal Outcome; Fusarium; Gingival Diseases; Humans; Immunocompromised Host; Leukemia, Myeloid, Acute; Male; Maxillary Diseases; Mercaptopurine; Mycoses; Necrosis; Prednisolone; Ulcer; Vindesine

1995
Chemosensitivity to triazene compounds and O6-alkylguanine-DNA alkyltransferase levels: studies with blasts of leukaemic patients.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1995, Volume: 6, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Cytarabine; Dacarbazine; Drug Screening Assays, Antitumor; Female; Humans; Leukemia, Myeloid, Acute; Male; Methyltransferases; Middle Aged; O(6)-Methylguanine-DNA Methyltransferase; Phenotype; Pilot Projects; Temozolomide

1995
[Detection of the resistance to Ara-C blast cells in acute myeloid leukemia using flow cytometry].
    Bulletin du cancer, 1995, Volume: 82, Issue:5

    Topics: Adolescent; Adult; Aged; Cell Cycle; Clone Cells; Cytarabine; DNA, Neoplasm; Drug Resistance; Female; Flow Cytometry; Humans; In Vitro Techniques; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Remission Induction; S Phase; Tumor Cells, Cultured

1995
Mitoxantrone and cytosine arabinoside as treatment for acute myeloblastic leukemia in older patients.
    Annals of hematology, 1995, Volume: 71, Issue:1

    Topics: Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Platelets; Cytarabine; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Mitoxantrone; Neutrophils; Remission Induction; Survival Analysis

1995
Sensitivity of hematopoietic progenitors of acute myeloblastic leukemia to new compounds derived from marine organisms.
    Leukemia, 1995, Volume: 9, Issue:9

    Topics: Alkaloids; Animals; Antineoplastic Agents; Cell Division; Cell Survival; Cytarabine; Drug Screening Assays, Antitumor; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Tumor Cells, Cultured; Urochordata

1995
Granulocyte colony-stimulating factor (CSF), macrophage-CSF, granulocyte-macrophage CSF, interleukin-3, and interleukin-6 levels in sera from children undergoing blood stem cell autografts.
    Blood, 1993, Feb-01, Volume: 81, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Child; Cytarabine; Daunorubicin; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-3; Interleukin-6; Leukemia, Myeloid, Acute; Leukocyte Count; Lymphoma, Non-Hodgkin; Macrophage Colony-Stimulating Factor; Male; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stem Cell Transplantation; Time Factors; Transplantation, Autologous

1993
Enhancement of cytosine arabinoside cytotoxicity by granulocyte/macrophage colony-stimulating factor and granulocyte colony-stimulating factor in a human myeloblastic leukemia cell line.
    Japanese journal of cancer research : Gann, 1993, Volume: 84, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Cell Division; Child; Cytarabine; DNA, Neoplasm; Drug Synergism; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hydrogen-Ion Concentration; Leukemia, Myeloid, Acute; RNA, Neoplasm; Solubility; Subcellular Fractions; Tumor Cells, Cultured

1993
Enhanced chemosensitivity of clonogenic blasts from patients with acute myeloid leukemia by G-CSF, IL-3 or GM-CSF stimulation.
    Leukemia, 1993, Volume: 7, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents; Cell Division; Cyclophosphamide; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-3; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplastic Stem Cells; Tumor Cells, Cultured; Tumor Stem Cell Assay

1993
[Enhanced sensitivity to cytosine arabinoside by combined stimulation of steel factor and GM-CSF in a factor-dependent leukemic cell line, MO7e--in terms of a possible clinical application to AML treatment].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1993, Volume: 34, Issue:7

    Topics: Adult; Aged; Cell Cycle; Cytarabine; Drug Screening Assays, Antitumor; Drug Synergism; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Cell Growth Factors; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Stem Cell Factor; Tumor Cells, Cultured

1993
Recombinant human granulocyte colony-stimulating factor in combination with continuous infusion of cytosine arabinoside for the treatment of refractory acute myelogenous leukemia.
    Acta haematologica, 1993, Volume: 89, Issue:3

    Topics: Bone Marrow; Cell Cycle; Cytarabine; Drug Therapy, Combination; Female; Flow Cytometry; Granulocyte Colony-Stimulating Factor; Humans; Infusions, Intravenous; Injections, Subcutaneous; Leukemia, Myeloid, Acute; Middle Aged; Recombinant Proteins; Remission Induction

1993
Effects of mast cell growth factor on Ara-C mediated acute myeloid leukemia cell killing.
    Stem cells (Dayton, Ohio), 1993, Volume: 11 Suppl 2

    Topics: Cell Cycle; Cell Death; Cell Division; Cytarabine; Drug Synergism; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Cell Growth Factors; Humans; Interleukin-3; Leukemia, Myeloid, Acute; Neoplasm Proteins; Neoplastic Stem Cells; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-kit; Receptor Protein-Tyrosine Kinases; Receptors, Colony-Stimulating Factor; Recombinant Fusion Proteins; Recombinant Proteins; Stem Cell Factor; Tumor Cells, Cultured; Tumor Stem Cell Assay

1993
Re: Pseudorelapse in acute myelomonocytic leukemia after high dose methylprednisolone.
    Leukemia research, 1995, Volume: 19, Issue:3

    Topics: Child; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute

1995
[Acute right ventricular insufficiency reversible following anthracycline treatment].
    Revista espanola de cardiologia, 1995, Volume: 48, Issue:3

    Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Doxorubicin; Female; Humans; Leukemia, Myeloid, Acute; Time Factors; Ventricular Dysfunction, Right

1995
Posttransfusion hepatitis after induction chemotherapy in acute nonlymphoblastic leukemia: implications for long-term management and outcome.
    Transfusion, 1995, Volume: 35, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Hepatitis; Humans; Incidence; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Survival Analysis; Time Factors; Transfusion Reaction; Treatment Outcome

1995
[Ischemic hepatitis due to anthracycline-induced cardiac insufficiency in a patient with acute myelocytic leukemia (M0)].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1995, Volume: 36, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cardiomyopathies; Cytarabine; Doxorubicin; Etoposide; Female; Hepatitis; Humans; Ischemia; Leukemia, Myeloid, Acute; Liver; Remission Induction

1995
Mechanism of cytosine arabinoside toxicity to the blast cells of acute myeloblastic leukemia: involvement of free radicals.
    Leukemia, 1995, Volume: 9, Issue:5

    Topics: Acetylcysteine; Antioxidants; Base Sequence; Blotting, Northern; Cytarabine; Down-Regulation; Drug Interactions; Drug Screening Assays, Antitumor; Free Radicals; Gene Expression Regulation, Leukemic; Humans; Hydrocortisone; Hydrogen Peroxide; Leukemia, Myeloid, Acute; Lymphocyte Activation; Lymphocytes; Molecular Sequence Data; Polymerase Chain Reaction; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured

1995
Encephalopathy with parkinsonian features in children following bone marrow transplantations and high-dose amphotericin B.
    Annals of neurology, 1995, Volume: 37, Issue:6

    Topics: Adolescent; Amphotericin B; Antineoplastic Agents; Aspergillosis; Bone Marrow Transplantation; Brain Diseases; Child; Cyclophosphamide; Cytarabine; Humans; Leukemia, Myeloid, Acute; Lung Diseases; Male; Methotrexate; Parkinson Disease; Radiation Injuries

1995
Intensive consolidation chemotherapy for newly diagnosed acute myeloid leukemia using a regime containing moderate dose cytosine arabinoside and mitoxantrone.
    Anti-cancer drugs, 1995, Volume: 6, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Survival Rate

1995
Fluorescence-labeling of nicks in DNA from leukemic blast cells as a measure of damage following cytosine arabinoside. Application to the study of regulated drug sensitivity.
    Leukemia, 1994, Volume: 8, Issue:12

    Topics: Cytarabine; DNA Damage; DNA Repair; DNA, Neoplasm; Drug Screening Assays, Antitumor; Flow Cytometry; Fluorescence; Genetic Techniques; Humans; Hydrocortisone; Kinetics; Leukemia, Myeloid, Acute; Tretinoin; Tumor Cells, Cultured; Tumor Stem Cell Assay

1994
Regulation by retinoic acid and hydrocortisone of the anthracycline sensitivity of blast cells of acute myeloblastic leukemia.
    Leukemia, 1994, Volume: 8, Issue:12

    Topics: Adult; Aged; Cell Survival; Cytarabine; Daunorubicin; DNA Damage; DNA Repair; DNA, Neoplasm; Dose-Response Relationship, Drug; Female; Genetic Techniques; Humans; Hydrocortisone; Kinetics; Leukemia, Myeloid, Acute; Male; Middle Aged; Tretinoin; Tumor Cells, Cultured; Tumor Stem Cell Assay

1994
[Treatment of acute myeloid leukemia in the elderly with low-dose cytosine arabinoside].
    Ugeskrift for laeger, 1994, Oct-24, Volume: 156, Issue:43

    Topics: Age Factors; Aged; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Retrospective Studies

1994
Parallel studies of clonogenic leukaemia cells and the leukaemia cell population as a whole in acute myelogenous leukaemia.
    European journal of cancer (Oxford, England : 1990), 1994, Volume: 30A, Issue:10

    Topics: Cell Cycle; Cell Division; Cytarabine; Daunorubicin; Gene Expression; Genes, myc; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Neoplasm Proteins; Neoplastic Stem Cells; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myb; Proto-Oncogene Proteins c-myc; Tritium; Tumor Stem Cell Assay

1994
Inhibition of bcl-2 with antisense oligonucleotides induces apoptosis and increases the sensitivity of AML blasts to Ara-C.
    Leukemia, 1995, Volume: 9, Issue:1

    Topics: Apoptosis; Base Sequence; Cytarabine; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Molecular Sequence Data; Oligonucleotides, Antisense; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured

1995
Aggressive chemotherapy for acute leukemia relapsed after transplantation.
    Leukemia & lymphoma, 1994, Volume: 15, Issue:1-2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Female; Humans; Idarubicin; Italy; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Male; Middle Aged; Neoplasm, Residual; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Retrospective Studies; Salvage Therapy; Survival Analysis; Treatment Outcome; Tretinoin; Vincristine

1994
Low expression of the deoxycytidine kinase (dCK) gene in a 1-beta-D-arabinofuranosylcytosine-resistant human leukemic cell line KY-Ra.
    Leukemia & lymphoma, 1994, Volume: 15, Issue:5-6

    Topics: Base Sequence; Blotting, Northern; Cytarabine; Deoxycytidine Kinase; Down-Regulation; Drug Resistance; Gene Expression; Humans; Leukemia, Myeloid, Acute; Molecular Sequence Data; RNA, Messenger; Tumor Cells, Cultured

1994
Cytosine arabinoside and mitoxantrone treatment of relapsed or refractory childhood leukemia: initial response and relationship to multidrug resistance gene 1.
    Medical and pediatric oncology, 1994, Volume: 22, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Carrier Proteins; Child; Child, Preschool; Cytarabine; Drug Evaluation; Drug Resistance; Female; Gene Expression; Humans; Infant; Leukemia; Leukemia, Myeloid, Acute; Male; Membrane Glycoproteins; Mitoxantrone; Molecular Sequence Data; Polymerase Chain Reaction; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction

1994
Acute myelogenous leukemia in pregnancy: fetal blood sampling and early effects of chemotherapy.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 1994, Volume: 44, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Fetal Blood; Fetal Growth Retardation; Fetus; Humans; Infant, Newborn; Leukemia, Myeloid, Acute; Mercaptopurine; Prednisolone; Pregnancy; Pregnancy Complications, Neoplastic; Ultrasonography, Prenatal

1994
1-beta-D-arabinofuranosylcytosine-, mitoxantrone-, and paclitaxel-induced apoptosis in HL-60 cells: improved method for detection of internucleosomal DNA fragmentation.
    Cancer chemotherapy and pharmacology, 1994, Volume: 34, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cytarabine; DNA Damage; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Administration Schedule; Electrophoresis, Agar Gel; Genome, Human; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Paclitaxel; Tumor Cells, Cultured

1994
Graft failure in children receiving HLA-mismatched marrow transplants with busulfan-containing regimens.
    Bone marrow transplantation, 1994, Volume: 13, Issue:6

    Topics: Adolescent; Adult; Age Factors; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Combined Modality Therapy; Cyclosporine; Cytarabine; Drug Therapy, Combination; Graft Rejection; Histocompatibility; HLA Antigens; Humans; Incidence; Leukemia, Myeloid, Acute; Middle Aged; Myelodysplastic Syndromes; Risk Factors; Tissue Donors

1994
Interactions between cladribine (2-chlorodeoxyadenosine) and standard antileukemic drugs in primary cultures of human tumor cells from patients with acute myelocytic leukemia.
    Leukemia, 1994, Volume: 8, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amsacrine; Antineoplastic Agents; Cladribine; Cytarabine; Daunorubicin; Drug Interactions; Drug Screening Assays, Antitumor; Drug Synergism; Etoposide; Female; Fluoresceins; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Tumor Cells, Cultured

1994
Teratogenic effects in a case of maternal treatment for acute myelocytic leukaemia--neonatal and infantile course.
    European journal of pediatrics, 1994, Volume: 153, Issue:7

    Topics: Abnormalities, Drug-Induced; Adult; Antineoplastic Combined Chemotherapy Protocols; Arm; Craniosynostoses; Cytarabine; Daunorubicin; Doxorubicin; Female; Humans; Infant, Newborn; Leukemia, Myeloid, Acute; Phenotype; Pregnancy; Pregnancy Complications, Neoplastic; Thioguanine

1994
[Acute leukemia in the elderly--a death sentence?].
    Harefuah, 1994, Volume: 127, Issue:1-2

    Topics: Age Factors; Aged; Aged, 80 and over; Cytarabine; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Remission Induction

1994
Calculation of individual dosage regimen of cytosine arabinoside (ara-C) based on metabolite levels in leukemic cells.
    Therapeutic drug monitoring, 1994, Volume: 16, Issue:4

    Topics: Arabinofuranosylcytosine Triphosphate; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid, Acute

1994
Mitoxantrone and standard dose cytosine arabinoside therapy in refractory or relapsed acute leukemia.
    Acta haematologica, 1994, Volume: 92, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Time Factors

1994
Acute myeloid leukemia in Manitoba. The consequences of standard "7 + 3" remission-induction therapy followed by high dose cytarabine postremission consolidation for myelosuppression, infectious morbidity, and outcome.
    Cancer, 1994, Jul-01, Volume: 74, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Humans; Infections; Leukemia, Myeloid, Acute; Male; Manitoba; Middle Aged; Multivariate Analysis; Neutropenia; Prognosis; Remission Induction; Retrospective Studies; Survival Rate; Treatment Outcome

1994
GM-CSF and low-dose araC treatment of AML in prolonged hypoplasia with residual leukemic cells after induction chemotherapy.
    Yonsei medical journal, 1994, Volume: 35, Issue:1

    Topics: Bone Marrow Diseases; Cytarabine; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

1994
Bone marrow purging in acute leukemia with alkyl-lysophospholipids: a new family of anticancer drugs.
    Leukemia & lymphoma, 1994, Volume: 13, Issue:1-2

    Topics: Antineoplastic Agents; Bone Marrow Purging; Bone Marrow Transplantation; Cyclophosphamide; Cytarabine; Etoposide; Humans; Leukemia, Myeloid, Acute; Leukocyte Count; Phospholipid Ethers; Platelet Count; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Survival Analysis; Whole-Body Irradiation

1994
Infection of elderly patients receiving high dose cytarabine-based chemotherapy for induction treatment of acute myelogenous leukemia (AML)
    Leukemia research, 1994, Volume: 18, Issue:8

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Infections; Leukemia, Myeloid, Acute; Male; Middle Aged; Retrospective Studies

1994
[Acute febrile neutrophilic dermatitis (Sweet's syndrome) during therapeutic agranulocytosis in acute myeloblastic leukemia].
    Annales de dermatologie et de venereologie, 1993, Volume: 120, Issue:12

    Topics: Agranulocytosis; Cytarabine; Female; Humans; Hydrocortisone; Leukemia, Myeloid, Acute; Middle Aged; Sweet Syndrome

1993
[Therapy-related acute non-lymphocytic leukemia (M2) with 7;11 chromosome translocation induced into complete remission by low dose cytosine arabinoside and cytarabine ocfosfate therapy].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 1994, Volume: 31, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleotides; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 7; Cytarabine; Cytidine Monophosphate; Female; Humans; Leukemia, Myeloid, Acute; Neoplasms, Second Primary; Remission Induction; Translocation, Genetic

1994
[High-dose chemoradiotherapy combined with recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) followed by autologous peripheral blood stem cell transplantation (PBSCT) in a case of refractory acute myelogenous leukemia (AML)].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1993, Volume: 34, Issue:8

    Topics: Adult; Blood Cell Count; Combined Modality Therapy; Cytarabine; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Recombinant Proteins

1993
Vitamin D3 administration and multidrug resistance in acute nonlymphoblastic leukemia.
    Acta haematologica, 1993, Volume: 89, Issue:4

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Cytarabine; Drug Resistance; Female; Humans; Hydroxycholecalciferols; Leukemia, Myeloid, Acute; Male; Membrane Glycoproteins; Middle Aged; Remission Induction

1993
The multiface morphology of acute leukemia.
    Haematologia, 1993, Volume: 25, Issue:3

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cell Differentiation; Cytarabine; Daunorubicin; Fatal Outcome; Female; Hematopoietic Stem Cells; Humans; Immunophenotyping; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction

1993
Case report: hypercalcemia in acute myeloblastic leukemia is caused by osteoclast activation.
    The American journal of the medical sciences, 1993, Volume: 306, Issue:3

    Topics: Biopsy; Bone and Bones; Bone Marrow; Cytarabine; Etidronic Acid; Humans; Hypercalcemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Osteoclasts

1993
Plasma and leukemic cell pharmacokinetics of high-dose N4-behenoyl-1-beta-D-arabinofuranosylcytosine in acute leukemia patients.
    Journal of clinical pharmacology, 1994, Volume: 34, Issue:1

    Topics: Antineoplastic Agents; Arabinofuranosyluracil; Chromatography, High Pressure Liquid; Cytarabine; Half-Life; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma

1994
Treatment of refractory undifferentiated acute myelogenous leukemia with all-trans-retinoic acid.
    American journal of hematology, 1994, Volume: 45, Issue:2

    Topics: Aged; Base Sequence; Biopsy; Bone Marrow; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Molecular Sequence Data; Remission Induction; Tretinoin

1994
Combination chemotherapy with DATV regimen in treatment of adult acute nonlymphocytic leukemia.
    Chinese medical journal, 1993, Volume: 106, Issue:11

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Thioguanine; Vincristine

1993
Acute myeloblastic leukemia with minimal myeloid differentiation (FAB AML-M0): a study of eleven cases.
    Leukemia & lymphoma, 1993, Volume: 12, Issue:1-2

    Topics: Adolescent; Adult; Aged; Antibodies, Monoclonal; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow; Chromosome Banding; Cytarabine; Daunorubicin; Doxorubicin; Female; Humans; Immunophenotyping; Leukemia, Myeloid, Acute; Lymphocytes; Male; Middle Aged; Peroxidase; Remission Induction; Thioguanine; Treatment Outcome

1993
Treatment of relapsed acute myeloid leukemia using GM-CSF before intensive chemotherapy.
    Leukemia & lymphoma, 1993, Volume: 12, Issue:1-2

    Topics: Adolescent; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Bone Marrow; Cell Cycle; Cytarabine; Drug Administration Schedule; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged; Recombinant Proteins; Recurrence; Treatment Outcome

1993
Low-dose ara-C in myelodysplastic syndromes (MDS) and acute leukemia following MDS: proposal for a predictive model.
    Leukemia & lymphoma, 1994, Volume: 12, Issue:5-6

    Topics: Acute Disease; Aged; Aged, 80 and over; Cytarabine; Humans; Leukemia, Myeloid, Acute; Middle Aged; Models, Biological; Myelodysplastic Syndromes; Survival Rate

1994
[Preliminary evaluation of adverse effects after administration of arabinoside cytosine (Ara-C) in high doses to children with acute myelogenous leukemia].
    Acta haematologica Polonica, 1994, Volume: 25, Issue:1

    Topics: Adolescent; Child; Child, Preschool; Cytarabine; Female; Hematologic Diseases; Humans; Leukemia, Myeloid, Acute; Male

1994
[Combined therapy with mitoxantrone and cytosine arabinoside as a first-line treatment in ANLL: preliminary results].
    Sangre, 1993, Volume: 38, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Cytarabine; Drug Evaluation; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Treatment Outcome

1993
[The comparative evaluation of the efficacy of different therapeutic plans in acute nonlymphocytic leukemias].
    Terapevticheskii arkhiv, 1993, Volume: 65, Issue:7

    Topics: Aclarubicin; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Doxorubicin; Drug Evaluation; Hematopoiesis; Humans; Idarubicin; Leukemia, Myeloid, Acute; Mitoxantrone; Prednisolone; Remission Induction; Time Factors; Vincristine

1993
Effects of rhGM-CSF on myeloid clonogenic cells in acute myelogenous leukemia patients.
    Leukemia & lymphoma, 1993, Volume: 10, Issue:3

    Topics: Adult; Aged; Blood Cells; Bone Marrow; Clone Cells; Cytarabine; Gene Expression Regulation, Leukemic; Genes, myc; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cells; Humans; Immunologic Factors; Leukemia, Myeloid, Acute; Middle Aged; Neoplastic Stem Cells; Oncogenes; Recombinant Proteins; S Phase; Tumor Cells, Cultured; Tumor Stem Cell Assay

1993
In vivo accumulation of etoposide in peripheral leukemic cells in patients treated for acute myeloblastic leukemia; relation to plasma concentrations and protein binding.
    Leukemia & lymphoma, 1993, Volume: 10, Issue:4-5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Blood Proteins; Cytarabine; Etoposide; Female; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Neoplastic Stem Cells; Protein Binding; Serum Albumin; Topoisomerase II Inhibitors

1993
Handling punctate keratitis resulting from systemic cytarabine.
    Annals of ophthalmology, 1993, Volume: 25, Issue:8

    Topics: Adult; Chloramphenicol; Corneal Opacity; Cytarabine; Glucocorticoids; Humans; Keratitis; Leukemia, Myeloid, Acute; Male; Ointments; Premedication; Visual Acuity

1993
Translocation (2;4)(p23;q25): an additional case of a new recurrent anomaly in acute myeloid leukemia.
    Cancer genetics and cytogenetics, 1993, Oct-15, Volume: 70, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chromosome Banding; Chromosomes, Human, Pair 2; Chromosomes, Human, Pair 4; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Translocation, Genetic

1993
[Treatment of myelodysplastic syndrome by combined traditional Chinese medicine and Western medicine therapy].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1993, Volume: 13, Issue:7

    Topics: Adolescent; Adult; Aged; Cell Transformation, Neoplastic; Cytarabine; Drugs, Chinese Herbal; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Pyridoxine; Stanozolol; Tretinoin

1993
Treatment of relapsed or refractory acute leukemia in childhood with bisantrene combined with high dose aracytine.
    Medical and pediatric oncology, 1994, Volume: 22, Issue:2

    Topics: Adolescent; Adult; Anthracenes; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Follow-Up Studies; Heart Diseases; Hematologic Diseases; Humans; Infant; Kidney Diseases; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction

1994
Modulation of intracellular metabolism of cytosine arabinoside in acute myeloid leukemia by granulocyte-macrophage colony-stimulating factor.
    Leukemia, 1994, Volume: 8, Issue:2

    Topics: Adolescent; Adult; Aged; Arabinofuranosylcytosine Triphosphate; Cytarabine; Deoxycytidine Kinase; DNA Polymerase II; DNA-Directed DNA Polymerase; DNA, Neoplasm; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Middle Aged; S Phase; Thymidine Kinase; Tumor Cells, Cultured

1994
[Short-term intensive consolidation chemotherapy in the treatment of acute nonlymphocytic leukemia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:2

    Topics: Aclarubicin; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Prognosis; Survival Rate; Vinblastine; Vincristine

1994
A cell culture model for the treatment of acute myeloblastic leukemia with fludarabine and cytosine arabinoside.
    Leukemia, 1993, Volume: 7, Issue:7

    Topics: Antineoplastic Agents; Cell Survival; Cells, Cultured; Cytarabine; Drug Administration Schedule; Drug Synergism; Humans; In Vitro Techniques; Leukemia, Myeloid, Acute; Methylcellulose; Vidarabine

1993
Recombinant GM-CSF modulates the metabolism of cytosine arabinoside in leukemic cells in bone marrow.
    Leukemia research, 1993, Volume: 17, Issue:7

    Topics: Arabinofuranosylcytosine Triphosphate; Bone Marrow; Bone Marrow Cells; Cytarabine; Deoxycytosine Nucleotides; DNA, Neoplasm; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Intracellular Fluid; Kinetics; Leukemia, Myeloid, Acute; Leukocytes, Mononuclear; Recombinant Proteins; S Phase; Tritium; Tumor Cells, Cultured

1993
Dynamics of interaction between DNA-specific antitumor agents and serum-contained cytokines in the initiation of ML-1 human myeloblastic leukemia cell differentiation.
    Leukemia, 1993, Volume: 7, Issue:8

    Topics: Animals; Antineoplastic Agents; Cattle; Cell Differentiation; Cytarabine; Cytokines; Dactinomycin; Daunorubicin; DNA, Neoplasm; Drug Synergism; Humans; Leukemia, Myeloid, Acute; Monocytes; Transforming Growth Factor beta; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1993
Prediction of chemotherapy response in human leukemia using in vitro chemosensitivity test.
    Leukemia research, 1993, Volume: 17, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Coloring Agents; Cytarabine; Daunorubicin; Drug Screening Assays, Antitumor; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Tetrazolium Salts; Thiazoles

1993
Changes in the oral microflora during cytotoxic chemotherapy in children being treated for acute leukemia.
    Oral surgery, oral medicine, and oral pathology, 1993, Volume: 76, Issue:2

    Topics: Adolescent; Analysis of Variance; Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bacterial Infections; Candida albicans; Candidiasis, Oral; Chi-Square Distribution; Child; Child, Preschool; Chlorhexidine; Colony Count, Microbial; Cytarabine; Daunorubicin; Etoposide; Female; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Infant; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Mouth; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Streptococcus mutans; Thioguanine; Trimethoprim, Sulfamethoxazole Drug Combination; Vincristine

1993
Treatment of relapsing and refractory adult acute myeloid leukemia according to in vitro clonogenic leukemic cell drug sensitivity.
    Leukemia & lymphoma, 1993, Volume: 10, Issue:1-2

    Topics: Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Humans; In Vitro Techniques; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Pilot Projects; Prospective Studies; Recurrence; Salvage Therapy; Tumor Stem Cell Assay

1993
Long-term outcome of patients with acute myelogenous leukemia: the role of maintenance therapy, consolidation therapy and the predictive value of two in vitro assays.
    Leukemia & lymphoma, 1993, Volume: 10, Issue:1-2

    Topics: Arabinofuranosylcytosine Triphosphate; Cytarabine; Humans; In Vitro Techniques; Leukemia, Myeloid, Acute; Predictive Value of Tests; Prognosis; Recurrence; Remission Induction; Treatment Outcome; Tumor Stem Cell Assay

1993
Orbito-ocular granulocytic sarcoma (OOGS) and acute myeloblastic leukemia (AML) with duplication of Philadelphia chromosome.
    Cancer genetics and cytogenetics, 1993, Volume: 69, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Combined Modality Therapy; Cytarabine; Dexamethasone; Doxorubicin; Etoposide; Eye Neoplasms; Humans; Karyotyping; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Methotrexate; Multigene Family; Neoplasms, Multiple Primary; Orbital Neoplasms; Philadelphia Chromosome; Thioguanine

1993
Prognostic significance of myeloperoxidase containing blast cells in acute myelogenous leukaemia.
    The Indian journal of medical research, 1993, Volume: 98

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Peroxidase; Prognosis; Recurrence; Remission Induction

1993
Malignant fibrous histiocytoma following bone marrow transplantation for acute leukemia.
    Transplantation proceedings, 1993, Volume: 25, Issue:3

    Topics: Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Bone Neoplasms; Combined Modality Therapy; Cytarabine; Daunorubicin; Graft vs Host Disease; Histiocytoma, Benign Fibrous; Humans; Leukemia, Myeloid, Acute; Male; Methotrexate; Radiography

1993
Fludarabine potentiates metabolism of cytarabine in patients with acute myelogenous leukemia during therapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1993, Volume: 11, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Drug Synergism; Humans; In Vitro Techniques; Leukemia, Myeloid, Acute; Middle Aged; Recurrence; Treatment Outcome; Vidarabine

1993
Idarubicin in combination with intermediate-dose cytarabine and VP-16 in the treatment of refractory or rapidly relapsed patients with acute myeloid leukemia. The GIMEMA Cooperative Group.
    Leukemia, 1993, Volume: 7, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Drug Administration Schedule; Drug Resistance; Etoposide; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Remission Induction

1993
On the interaction between cytosine arabinoside and etoposide in vivo and in vitro.
    European journal of haematology, 1993, Volume: 50, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Cytarabine; Drug Interactions; Etoposide; Humans; In Vitro Techniques; Kinetics; Leukemia, Myeloid, Acute; Phosphorylation

1993
High frequency of etoposide (VP-16)-related secondary leukemia in children with non-Hodgkin's lymphoma.
    The American journal of pediatric hematology/oncology, 1993, Volume: 15, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparagine; Child; Child, Preschool; Chromosome Aberrations; Chromosomes, Human, Pair 11; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Life Tables; Lymphoma, Non-Hodgkin; Male; Mercaptopurine; Methotrexate; Neoplasms, Second Primary; Risk; Vincristine

1993
All-trans retinoic acid plus low doses of cytarabine for the treatment of "poor-risk" acute myeloid leukemias.
    Annals of hematology, 1993, Volume: 66, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Tretinoin

1993
[Alterations in morphological and phenotypical features of leukemic cells relapse 7 years after onset in a case of acute non-lymphocytic leukemia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Kidney Neoplasms; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Neoplasms, Second Primary; Prednisolone

1993
Induction therapy for acute myelogenous leukemia in patients over 60 years with intermediate-dose cytosine arabinoside, mitoxantrone and etoposide.
    Leukemia & lymphoma, 1993, Volume: 9, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Recurrence; Remission Induction

1993
Treatment of relapsed or refractory AML with intermediate-dose arabinosylcytosine (ara-C): confirmation of the importance of ara-C triphosphate formation in mediating response to ara-C.
    Leukemia & lymphoma, 1993, Volume: 10 Suppl

    Topics: Adult; Aged; Arabinofuranosylcytosine Triphosphate; Clinical Protocols; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid, Acute; Middle Aged; Recurrence; Remission Induction

1993
Disseminated subcutaneous Nocardia asteroides abscesses in a patient after bone marrow transplantation.
    Bone marrow transplantation, 1993, Volume: 11, Issue:4

    Topics: Abscess; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Purging; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Female; Humans; Immunocompromised Host; Incidence; Leukemia, Myeloid, Acute; Mercaptopurine; Neutropenia; Nocardia asteroides; Nocardia Infections; Opportunistic Infections; Prednisolone; Remission Induction; Skin Diseases, Infectious

1993
Is there still a role for low-dose cytosine arabinoside in de novo acute myeloid leukemia in the elderly? A report on 77 cases.
    Annals of hematology, 1993, Volume: 66, Issue:5

    Topics: Aged; Aged, 80 and over; Chromosome Aberrations; Chromosomes, Human, Pair 5; Chromosomes, Human, Pair 7; Cytarabine; Female; Humans; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Remission Induction; Survival Rate

1993
[Effect of 2-chlorodeoxyadenosine, arabinoside cytosine and doxorubicin on acute myeloid leukemia clonogenic cell proliferation].
    Acta haematologica Polonica, 1995, Volume: 26, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cladribine; Cytarabine; Doxorubicin; Humans; Leukemia, Myeloid, Acute; Tumor Cells, Cultured

1995
New statistical strategy for monitoring safety and efficacy in single-arm clinical trials.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1996, Volume: 14, Issue:1

    Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Bayes Theorem; Clinical Trials, Phase II as Topic; Cyclosporine; Cytarabine; Humans; Idarubicin; Leukemia, Myeloid, Acute; Mathematical Computing; Monitoring, Physiologic; Probability; Remission Induction; Research Design

1996
Invasive fungal disease in adults undergoing remission-induction therapy for acute myeloid leukemia: the pathogenetic role of the antileukemic regimen.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1995, Volume: 21, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Fungemia; Fungi; Humans; Intestinal Mucosa; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Mycoses; Remission Induction; Retrospective Studies

1995
[Acute myelogenous leukemia with diabetes insipidus without desmopression administration by anti-leukemic chemotherapy].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1995, Volume: 36, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Deamino Arginine Vasopressin; Diabetes Insipidus; Female; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Prednisolone; Renal Agents

1995
Idarubicin in combination with cytarabine and VP-16 in the treatment of post myelodysplastic syndrome acute myeloblastic leukemia (MDS-AML).
    Leukemia & lymphoma, 1995, Volume: 19, Issue:5-6

    Topics: Actuarial Analysis; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease Progression; Disease-Free Survival; Etoposide; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Remission Induction

1995
Cutaneous eruption of lymphocyte recovery mimicking mycosis fungoides in a patient with acute myelocytic leukemia.
    Journal of cutaneous pathology, 1995, Volume: 22, Issue:5

    Topics: CD4 Antigens; Cytarabine; Diagnosis, Differential; Drug Therapy, Combination; Humans; Idarubicin; Leukemia, Myeloid, Acute; Lymphocytes; Male; Middle Aged; Mycosis Fungoides; Skin

1995
Translocation (12;15)(p13;q13) in a patient with relapsed acute myeloid leukemia.
    Cancer genetics and cytogenetics, 1996, Volume: 86, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 12; Chromosomes, Human, Pair 15; Cytarabine; Daunorubicin; Female; Humans; Idarubicin; Karyotyping; Leukemia, Myeloid, Acute; Recurrence; Translocation, Genetic

1996
Treatment of newly-diagnosed acute myelogenous leukaemia in patients aged 80 years and above.
    British journal of haematology, 1996, Volume: 93, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Cytarabine; Daunorubicin; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Medical Futility; Probability; Survival Rate; Treatment Outcome

1996
A new sensitive method for determination of intracellular 1-beta-D-arabinofuranosylcytosine 5'-triphosphate content in human materials in vivo.
    Cancer research, 1996, Apr-15, Volume: 56, Issue:8

    Topics: Alkaline Phosphatase; Arabinofuranosylcytosine Triphosphate; Blast Crisis; Cell Line; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cytarabine; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Radioimmunoassay; Sensitivity and Specificity; Tumor Cells, Cultured

1996
Translocation (2;3)(p13;q26) in two cases of myeloid malignancies. Acute myeloblastic leukemia (M2) and blastic phase of chronic myeloid leukemia.
    Cancer genetics and cytogenetics, 1996, Volume: 87, Issue:2

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Doxorubicin; Humans; Karyotyping; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Prednisolone; Prednisone; Translocation, Genetic; Vincristine

1996
Postremission therapy with two different dose regimens of cytarabine in adults with acute myelogenous leukemia.
    Leukemia research, 1995, Volume: 19, Issue:12

    Topics: Actuarial Analysis; Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Retrospective Studies; Survival Rate

1995
Post-transcriptional regulation of bcl-2 in acute myeloblastic leukemia: significance for response to chemotherapy.
    Leukemia, 1996, Volume: 10, Issue:3

    Topics: Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Blotting, Northern; Blotting, Western; Cytarabine; Daunorubicin; Down-Regulation; Gene Expression Regulation, Leukemic; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hydrocortisone; Leukemia, Myeloid, Acute; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Remission Induction; RNA, Messenger; Transcription, Genetic; Transcriptional Activation; Tretinoin; Tumor Cells, Cultured

1996
Intensive induction and consolidation chemotherapy in a young woman with acute myeloid leukemia and severe chronic renal failure.
    Annals of hematology, 1996, Volume: 72, Issue:5

    Topics: Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Contraindications; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Kidney Failure, Chronic; Leukemia, Myeloid, Acute; Mitoxantrone

1996
The effect of 9-beta-D-arabinofuranosyl-2-fluoroadenine and 1-beta-D-arabinofuranosylcytosine on the cell cycle phase distribution, topoisomerase II level, mitoxantrone cytotoxicity, and DNA strand break production in K562 human leukemia cells.
    Cancer chemotherapy and pharmacology, 1996, Volume: 38, Issue:3

    Topics: Antineoplastic Agents; Cell Cycle; Cytarabine; DNA Damage; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Humans; Immunoblotting; Leukemia, Myeloid, Acute; Mitoxantrone; Protein Binding; Tumor Cells, Cultured; Vidarabine

1996
Factors predicting complete remission and subsequent disease-free survival after a second course of induction therapy in patients with acute myelogenous leukemia resistant to the first.
    Leukemia, 1996, Volume: 10, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Drug Resistance, Neoplasm; Humans; Leukemia, Myeloid, Acute; Logistic Models; Middle Aged; Prognosis; Remission Induction; Risk Factors

1996
[A case of acute myelocytic leukemia in relapse controlled by continuous home administration of Ara-C].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:4

    Topics: Antimetabolites, Antineoplastic; Cytarabine; Home Care Services, Hospital-Based; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Quality of Life

1996
Generation of reactive oxygen intermediates after treatment of blasts of acute myeloblastic leukemia with cytosine arabinoside: role of bcl-2.
    Leukemia, 1996, Volume: 10, Issue:7

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Blast Crisis; Calcium; Cell Membrane; Cytarabine; Flow Cytometry; Glutathione; Humans; Leukemia, Myeloid, Acute; Lipid Peroxidation; Neoplastic Stem Cells; Oxidation-Reduction; Oxidative Stress; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Transfection; Tumor Cells, Cultured; Tumor Stem Cell Assay

1996
A combination chemotherapy with low doses of cytarabine and etoposide for high risk myelodysplastic syndromes and their leukemic stage. A pilot study.
    Cancer, 1996, Aug-01, Volume: 78, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Etoposide; Female; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Pilot Projects; Remission Induction; Risk Factors

1996
Bilateral submandibular salivary gland enlargement during chemotherapy for acute myeloid leukaemia--beneficial effect of propranolol.
    Acta haematologica, 1996, Volume: 96, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Propranolol; Submandibular Gland

1996
Clonality switch in acute myeloid leukemia.
    Leukemia & lymphoma, 1996, Volume: 22, Issue:1-2

    Topics: Adult; Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Bone Marrow; Clone Cells; Cyclophosphamide; Cytarabine; Daunorubicin; Disease Progression; Dosage Compensation, Genetic; Female; Hematopoiesis; Heterozygote; Humans; Leukemia, Myeloid, Acute; Neoplastic Stem Cells; Prednisolone; Remission Induction; Thioguanine; Vincristine

1996
Marked bone marrow eosinophilia at the time of relapse of acute myeloblastic leukaemia in association with the appearance of translocation t(12;20)(q24;q11).
    Leukemia & lymphoma, 1996, Volume: 22, Issue:1-2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Chromosomes, Human, Pair 12; Chromosomes, Human, Pair 20; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Cytarabine; Daunorubicin; Eosinophilia; Etoposide; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Neoplasm Recurrence, Local; Remission Induction; Translocation, Genetic

1996
Isolated leukemia cutis and CNS involvement in combination with cytogenetic findings of trisomy 8--two case reports.
    Leukemia & lymphoma, 1995, Volume: 20, Issue:1-2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Central Nervous System Neoplasms; Chromosomes, Human, Pair 8; Cytarabine; Drug Resistance, Neoplasm; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Skin Neoplasms; Trisomy; Vidarabine

1995
The combination of melphalan, cyclophosphamide and cytosine arabinoside as a conditioning regimen for autologous bone marrow transplantation for acute leukemia.
    Chinese medical journal, 1996, Volume: 109, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Purging; Bone Marrow Transplantation; Cyclophosphamide; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Male; Melphalan; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma

1996
Intracellular metabolism of Ara-C and resulting DNA fragmentation and apoptosis of human AML HL-60 cells possessing disparate levels of Bcl-2 protein.
    Leukemia, 1996, Volume: 10, Issue:11

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Cytarabine; DNA Damage; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Proto-Oncogene Proteins c-bcl-2

1996
Exacerbation of hepatitis in hepatitis B carriers following chemotherapy for haematological malignancies.
    Annals of the Academy of Medicine, Singapore, 1996, Volume: 25, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carrier State; Chronic Disease; Cyclophosphamide; Cytarabine; Daunorubicin; Disease Progression; Doxorubicin; Etoposide; Female; Hepatic Encephalopathy; Hepatitis B; Humans; Leucovorin; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Prednisone; Vincristine

1996
A role for paclitaxel in the combination chemotherapy of acute myeloblastic leukaemia: preclinical cell culture studies.
    British journal of haematology, 1996, Volume: 95, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cytarabine; Dose-Response Relationship, Drug; Drug Synergism; Female; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Paclitaxel; Tretinoin; Tumor Cells, Cultured

1996
[Successful treatment of acute non-lymphoblastic leukemia from myelodysplastic syndrome by combination of human macrophage colony-stimulating factor (M-CSF) and low dose cytosine arabinoside: M-CSF-induced proliferation and tyrosine phosphorylation in leu
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1996, Volume: 37, Issue:11

    Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Blast Crisis; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Macrophage Colony-Stimulating Factor; Myelodysplastic Syndromes; Phosphorylation; Tyrosine

1996
[8;21 translocation acute myelocytic leukemia developing in the second trimester of pregnancy with successful delivery].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1996, Volume: 37, Issue:11

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Cytarabine; Daunorubicin; Female; Humans; Infant, Newborn; Labor, Obstetric; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Prednisolone; Pregnancy; Pregnancy Complications, Neoplastic; Remission Induction; Translocation, Genetic

1996
Phase I clinical and laboratory evaluation of topotecan and cytarabine in patients with acute leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blast Crisis; Camptothecin; Cytarabine; Drug Administration Schedule; Female; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Topotecan

1997
Low dose cytosine arabinoside in the treatment of acute non-lymphoblastic leukemia.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 1996, Volume: 79, Issue:9

    Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction

1996
[The detection of minimal residual disease by DEK/CAN chimeric m-RNA in a case of AML M2 with translocation t(6;9) (p23;q34) after chemotherapy and peripheral blood stem cell transplantation].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1997, Volume: 38, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 6; Chromosomes, Human, Pair 9; Combined Modality Therapy; Cytarabine; Daunorubicin; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Mitoxantrone; Neoplasm, Residual; Oncogene Proteins; Oncogene Proteins, Fusion; Polymerase Chain Reaction; Prednisolone; Recombinant Fusion Proteins; RNA, Messenger; Translocation, Genetic

1997
[Early establishment of bone marrow hypoplasia by antileukemic chemotherapy with concurrent rhG-CSF in a case of acute myelogenous leukemia complicated with intestinal perforation].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1997, Volume: 38, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Daunorubicin; Duodenal Diseases; Granulocyte Colony-Stimulating Factor; Humans; Intestinal Perforation; Karyotyping; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisolone; Recombinant Proteins; Remission Induction

1997
Acute abdomen due to endometriosis as a diagnostic and therapeutic challenge in the treatment of acute myelocytic leukemia.
    Annals of hematology, 1997, Volume: 74, Issue:1

    Topics: Abdomen, Acute; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Endometriosis; Etoposide; Humans; Idarubicin; Leukemia, Myeloid, Acute; Middle Aged

1997
[Growth inhibitory effects of ubenimex on leukemic cell lines resistant to chemotherapeutic agents].
    The Japanese journal of antibiotics, 1996, Volume: 49, Issue:12

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Division; Cytarabine; Daunorubicin; Depression, Chemical; Drug Combinations; Drug Resistance, Neoplasm; Drug Synergism; Humans; Leucine; Leukemia, Myeloid, Acute; Mercaptopurine; Tumor Cells, Cultured

1996
Complete remission following donor PBSC after low-dose cytarabine chemotherapy for early relapse of acute myelogenous leukemia after allogeneic stem cell transplantation.
    Bone marrow transplantation, 1997, Volume: 19, Issue:4

    Topics: Antimetabolites, Antineoplastic; Combined Modality Therapy; Cytarabine; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Middle Aged; Remission Induction; Transplantation, Homologous

1997
Long term follow-up of patients with acute myelogenous leukemia who received the daunorubicin, vincristine, and cytosine arabinoside regimen.
    Cancer, 1997, Apr-01, Volume: 79, Issue:7

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Vincristine

1997
Retreatment with low-dose cytarabine in patients with previous central nervous system toxicity.
    American journal of hematology, 1997, Volume: 54, Issue:4

    Topics: Cerebellar Diseases; Cytarabine; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

1997
Spontaneous remission in acute myelogenous leukemia: a case report.
    Zhonghua yi xue za zhi = Chinese medical journal; Free China ed, 1997, Volume: 59, Issue:2

    Topics: Antimetabolites, Antineoplastic; Blood Component Transfusion; Cytarabine; Female; Graft vs Host Disease; Humans; Leukemia, Myeloid, Acute; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Regression, Spontaneous; Remission Induction

1997
Angioimmunoblastic lymphadenopathy with disseminated human herpesvirus 6 infection in a patient with acute myeloblastic leukemia.
    Leukemia, 1997, Volume: 11, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Autopsy; Cytarabine; DNA, Viral; Fatal Outcome; Fever; Herpesviridae Infections; Herpesvirus 6, Human; Humans; Hypergammaglobulinemia; Idarubicin; Immunoblastic Lymphadenopathy; Immunophenotyping; Leukemia, Myeloid, Acute; Lymph Nodes; Male; Middle Aged; Pericarditis; Polymerase Chain Reaction; Remission Induction; Tumor Virus Infections

1997
Relationships between the mitochondrial permeability transition and oxidative stress during ara-C toxicity.
    Cancer research, 1997, Jun-15, Volume: 57, Issue:12

    Topics: Calcium; Cytarabine; Flow Cytometry; Humans; Intracellular Membranes; Leukemia, Myeloid, Acute; Membrane Potentials; Mitochondria; Oxidative Stress; Permeability; Phosphatidylserines; Reactive Oxygen Species; Time Factors; Tumor Cells, Cultured

1997
Early transformation to acute myeloblastic leukaemia with the acquisition of inv(16) in Ph positive chronic granulocytic leukaemia.
    Leukemia research, 1997, Volume: 21, Issue:5

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosome Disorders; Chromosome Inversion; Chromosome Mapping; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 22; Chromosomes, Human, Pair 9; Cytarabine; Fatal Outcome; Humans; Idarubicin; Karyotyping; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Philadelphia Chromosome

1997
[Treatment of acute myelogenous leukemia in patients more than 80 years old].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:9

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Prednisolone; Quality of Life; Remission Induction

1997
Disseminated tuberculosis treated with amikacin in a patient with acute myelocytic leukemia.
    Acta oncologica (Stockholm, Sweden), 1997, Volume: 36, Issue:4

    Topics: Abscess; Adrenal Gland Diseases; Aged; Amikacin; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Antitubercular Agents; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Male; Tuberculosis; Tuberculosis, Hepatic; Tuberculosis, Pulmonary

1997
Acute myeloblastic leukemia in adults.
    The Journal of the Association of Physicians of India, 1995, Volume: 43, Issue:2

    Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cause of Death; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Thioguanine; Treatment Outcome

1995
[Observation and care in high-dose cytarabine treatment of acute myelogenous leukemia].
    Zhonghua hu li za zhi = Chinese journal of nursing, 1996, Volume: 31, Issue:11

    Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Child; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Nursing Assessment

1996
Chemotherapy-induced acral erythema in leukemic patients: a report of 15 cases.
    International journal of dermatology, 1997, Volume: 36, Issue:8

    Topics: Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Doxorubicin; Erythema; Female; Humans; Immunosuppressive Agents; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Middle Aged; Prospective Studies; Recurrence

1997
[Acute myeloblastic leukemia showing pronounced skin infiltration during administration of low-dose cytarabine and etoposide with granulocyte colony-stimulating factor].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1997, Volume: 38, Issue:9

    Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Skin

1997
FLAG is a useful regimen for poor prognosis adult myeloid leukaemias and myelodysplastic syndromes.
    Leukemia & lymphoma, 1997, Volume: 27, Issue:1-2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Middle Aged; Myelodysplastic Syndromes; Prognosis; Vidarabine

1997
[IL-2 post-autologous transplant of hematopoietic stem cells].
    Sangre, 1997, Volume: 42 Suppl 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Idarubicin; Interleukin-2; Leukemia, Myeloid, Acute; Remission Induction; Transplantation, Autologous

1997
High remission rate, short remission duration in patients with refractory anemia with excess blasts (RAEB) in transformation (RAEB-t) given acute myelogenous leukemia (AML)-type chemotherapy in combination with granulocyte-CSF (G-CSF).
    Cytokines and molecular therapy, 1995, Volume: 1, Issue:1

    Topics: Adult; Anemia, Refractory, with Excess of Blasts; Bone Marrow; Chromosome Aberrations; Chromosome Disorders; Confidence Intervals; Cytarabine; Disease-Free Survival; Drug Administration Schedule; Drug Therapy, Combination; Environment, Controlled; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Karyotyping; Leukemia, Myeloid, Acute; Middle Aged; Platelet Count; Probability; Prognosis; Recurrence; Remission Induction; Retrospective Studies; Survival Rate; Vidarabine

1995
Occurrence and therapy of secondary acute myeloid leukaemia in two HIV-infected patients.
    AIDS (London, England), 1998, Jan-22, Volume: 12, Issue:2

    Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Lymphoma, AIDS-Related; Male; Neoplasms, Second Primary; Viral Load

1998
High dose cytosine arabinoside is a major risk factor for the development of hepatosplenic candidiasis in patients with leukemia.
    Leukemia & lymphoma, 1997, Volume: 27, Issue:5-6

    Topics: Adult; Antibiotic Prophylaxis; Antimetabolites, Antineoplastic; Candidiasis; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neutropenia; Opportunistic Infections; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Risk Factors

1997
Cytosine arabinoside-induced vasculitis.
    Mayo Clinic proceedings, 1998, Volume: 73, Issue:3

    Topics: Adult; Antimetabolites, Antineoplastic; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Vasculitis

1998
Cranial irradiation and permeability of blood-brain barrier to cytosine arabinoside in children with acute leukemia.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:1

    Topics: Adolescent; Antimetabolites, Antineoplastic; Blood-Brain Barrier; Brain Neoplasms; Child; Child, Preschool; Cranial Irradiation; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma

1998
[Giant platelet-like cell fragments produced from abnormal promyelocytes in acute myelogenous leukemia].
    Rinsho byori. The Japanese journal of clinical pathology, 1998, Volume: 46, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Granulocytes; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Platelet Count; Prednisolone; Remission Induction

1998
[Retrospective analysis of elderly patients > or = 60 years of age with acute leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1998, Volume: 39, Issue:3

    Topics: Aclarubicin; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Daunorubicin; DNA; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Retrospective Studies; Vincristine

1998
Follicular mucinosis as a presenting sign of acute myeloblastic leukemia.
    Journal of the American Academy of Dermatology, 1998, Volume: 38, Issue:5 Pt 2

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cytarabine; Doxorubicin; Follow-Up Studies; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Mucinosis, Follicular; Mycosis Fungoides; Paraneoplastic Syndromes; Remission Induction; Skin Neoplasms; T-Lymphocytes

1998
[Consolidation therapy with high-dose cytarabine and daunorubicin for prolonged disease free survival in acute myelocytic leukemia].
    Zhonghua nei ke za zhi, 1996, Volume: 35, Issue:8

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Male; Middle Aged

1996
Clinical characteristics of patients with de novo acute myeloid leukaemia and isolated trisomy 11: a Cancer and Leukemia Group B study.
    British journal of haematology, 1998, Volume: 101, Issue:3

    Topics: Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Chromosomes, Human, Pair 11; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Megakaryoblastic, Acute; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Platelet Count; Treatment Outcome; Trisomy

1998
Cytarabine-induced acral erythema: a localized form of toxic epidermal necrolysis?
    Journal of the European Academy of Dermatology and Venereology : JEADV, 1998, Volume: 10, Issue:3

    Topics: Antimetabolites, Antineoplastic; Cytarabine; Diagnosis, Differential; Erythema; Hand Dermatoses; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Necrosis

1998
Acute myelogenous leukemia in Down's syndrome: report of a single pediatric institution using a BFM treatment strategy.
    Leukemia research, 1998, Volume: 22, Issue:5

    Topics: Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Argentina; Bone Marrow Cells; Child, Preschool; Cytarabine; Down Syndrome; Etoposide; Female; Humans; Idarubicin; Infant; Karyotyping; Leukemia, Myeloid, Acute; Male; Retrospective Studies; Treatment Outcome

1998
Accumulation of arabinosyluracil 5'-triphosphate during arabinosylcytosine therapy in circulating blasts of patients with acute myelogenous leukemia.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:7

    Topics: Antimetabolites, Antineoplastic; Arabinofuranosylcytosine Triphosphate; Cytarabine; Humans; Leukemia, Myeloid, Acute; Uridine Triphosphate

1998
Multiple inflammatory pseudotumors of the liver associated with acute myeloblastic leukemia.
    Internal medicine (Tokyo, Japan), 1998, Volume: 37, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Cytarabine; Daunorubicin; Diagnosis, Differential; Granuloma, Plasma Cell; Humans; Leukemia, Myeloid, Acute; Liver Abscess; Liver Diseases; Liver Neoplasms; Magnetic Resonance Imaging; Male; Mercaptopurine; Prednisolone; Tomography, X-Ray Computed

1998
Evidence for sinoatrial blockade associated with high dose cytarabine therapy.
    Leukemia research, 1998, Volume: 22, Issue:8

    Topics: Adult; Antimetabolites, Antineoplastic; Cytarabine; Dose-Response Relationship, Drug; Electrocardiography; Female; Humans; Leukemia, Myeloid, Acute; Sinoatrial Block

1998
[Petechiae, suffusions and cytarabine-induced erythema in treatment of acute myeloid leukemia].
    Schweizerische medizinische Wochenschrift, 1998, Jul-07, Volume: 128, Issue:27-28

    Topics: Aged; Antimetabolites, Antineoplastic; Cytarabine; Diagnosis, Differential; Drug Eruptions; Female; Humans; Leukemia, Myeloid, Acute; Purpura

1998
Outcome assessment of age group-specific (+/- 50 years) post-remission consolidation with high-dose cytarabine or bone marrow autograft for adult acute myelogenous leukemia.
    Haematologica, 1998, Volume: 83, Issue:7

    Topics: Bone Marrow Transplantation; Cytarabine; Dose-Response Relationship, Drug; Evaluation Studies as Topic; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Transplantation, Autologous; Treatment Outcome

1998
[Low-dose oral etoposide and subcutaneous injection of low-dose cytosine arabinoside (Et-A non i.v.) with or without minimum anthracycline for refractory acute non-lymphoblastic leukemia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1998, Volume: 25, Issue:10

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Remission Induction; Vindesine

1998
[Prognostic significance of CD7 expression in adult acute myeloid leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1998, Volume: 39, Issue:7

    Topics: Adolescent; Adult; Aged; Antigens, CD7; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Child, Preschool; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Middle Aged; Prednisolone; Prognosis; Survival Rate; Thioguanine; Tretinoin

1998
[Successful treatment with idarubicin in a pediatric case of t(8;21) acute myelogenous leukemia with additional chromosomal abnormalities at relapse].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1998, Volume: 39, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Combined Modality Therapy; Cytarabine; Etoposide; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Recurrence; Remission Induction; Translocation, Genetic; Treatment Outcome

1998
Remission of Crohn's disease following allogeneic bone marrow transplant for acute leukaemia.
    Hospital medicine (London, England : 1998), 1998, Volume: 59, Issue:7

    Topics: Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Bone Marrow Purging; Bone Marrow Transplantation; Crohn Disease; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Male; Thioguanine; Transplantation, Homologous

1998
An oxidative stress-mediated death pathway in irradiated human leukemia cells mapped using multilaser flow cytometry.
    Radiation research, 1998, Volume: 150, Issue:6

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Calcium; Cytarabine; Flow Cytometry; Gamma Rays; Genes, bcl-2; Glutathione; Humans; Lasers; Leukemia, Myeloid, Acute; Membrane Potentials; Mitochondria; Oxidative Stress; Phosphatidylserines; Reactive Oxygen Species; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53

1998
[Cytarabine-induced pericarditis].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1998, Volume: 39, Issue:11

    Topics: Aged; Cytarabine; Etoposide; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Pericarditis

1998
Carboplatin plus cytarabine in the treatment of high-risk acute myeloblastic leukemia.
    Leukemia, 1999, Volume: 13, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Risk Factors; Survival Rate; Treatment Outcome

1999
Suppressed neutrophil function as a risk factor for severe infection after cytotoxic chemotherapy in patients with acute nonlymphocytic leukemia.
    Annals of hematology, 1999, Volume: 78, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Fever; Humans; Idarubicin; Immunocompromised Host; Infections; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Mitoxantrone; N-Formylmethionine Leucyl-Phenylalanine; Neutropenia; Neutrophils; Phagocytosis; Respiratory Burst; Retrospective Studies; Risk Factors; Thioguanine; Vidarabine

1999
Splenic rupture in a patient with acute myeloid leukemia undergoing peripheral blood stem cell transplantation.
    Annals of hematology, 1999, Volume: 78, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Aspergillosis; Combined Modality Therapy; Cytarabine; Doxorubicin; Fatal Outcome; Female; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Hematoma; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Puerperal Disorders; Remission Induction; Rupture, Spontaneous; Shock; Splenic Rupture; Thioguanine

1999
Behenoyl cytarabine-associated reversible encephalopathy in a patient with acute myelogenous leukemia.
    Journal of Korean medical science, 1999, Volume: 14, Issue:1

    Topics: Adolescent; Antineoplastic Agents; Brain; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Magnetic Resonance Imaging; Radiography; Seizures

1999
Chemotherapy-induced inflammation in seborrheic keratoses mimicking disseminated herpes zoster.
    Journal of the American Academy of Dermatology, 1999, Volume: 40, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Cytarabine; Daunorubicin; Diagnosis, Differential; Drug Eruptions; Female; Herpes Zoster; Humans; Keratosis, Seborrheic; Leukemia, Myeloid, Acute; Skin; Substance Withdrawal Syndrome

1999
Transient effusive-constrictive pericarditis due to chemotherapy.
    Clinical cardiology, 1999, Volume: 22, Issue:4

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Echocardiography; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Pericardial Effusion; Pericarditis, Constrictive; Tomography, X-Ray Computed

1999
Bacteremia caused by a novel isolate resembling leptotrichia species in a neutropenic patient.
    Journal of clinical microbiology, 1999, Volume: 37, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bacteremia; Cytarabine; Gram-Negative Anaerobic Straight, Curved, and Helical Rods; Gram-Negative Bacterial Infections; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Microscopy, Electron; Middle Aged; Neutropenia; Phylogeny

1999
Effect of complete remission on survival in patients with acute myelogenous leukemia receiving first salvage therapy.
    Blood, 1999, May-01, Volume: 93, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Retrospective Studies; Salvage Therapy; Survival Analysis; Time Factors

1999
Transplantation of autologous peripheral blood progenitor cells procured after high-dose cytarabine-based consolidation chemotherapy for adults with secondary acute myelogenous leukemia in first remission.
    Leukemia & lymphoma, 1999, Volume: 33, Issue:5-6

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Female; Hematologic Diseases; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Survival Analysis; Transplantation, Autologous

1999
Acute myeloblastic leukemia (M0) with an unusual chromosomal abnormality: translocation (1;14)(p13;q32).
    Cancer genetics and cytogenetics, 1999, Volume: 111, Issue:2

    Topics: Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 14; Cytarabine; Female; HLA-DR Antigens; Humans; Idarubicin; Leukemia, Myeloid, Acute; Middle Aged; Peroxidase; Translocation, Genetic

1999
Sequential standard dose mitoxantrone and cytosine arabinoside for newly diagnosed adult acute myeloblastic leukemia.
    Neoplasma, 1999, Volume: 46, Issue:1

    Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Drug Administration Schedule; Humans; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Remission Induction; Treatment Failure; Treatment Outcome

1999
Altered multidrug resistance phenotype caused by anthracycline analogues and cytosine arabinoside in myeloid leukemia.
    Blood, 1999, Jun-15, Volume: 93, Issue:12

    Topics: Anthracyclines; Antimetabolites, Antineoplastic; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytarabine; Drug Resistance, Multiple; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Myeloid, Acute; Leukemia, T-Cell; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured

1999
Thiamine deficiency in a patient receiving chemotherapy for acute myeloblastic leukemia.
    American journal of hematology, 1999, Volume: 61, Issue:2

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Thiamine Deficiency

1999
Pseudotumor cerebri secondary to intermediate-dose cytarabine HCl.
    The Annals of pharmacotherapy, 1999, Volume: 33, Issue:5

    Topics: Acetazolamide; Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Child; Cytarabine; Diuretics; Humans; Leukemia, Myeloid, Acute; Male; Prednisone; Pseudotumor Cerebri

1999
Early allogeneic transplantation for refractory or relapsed acute leukaemia following remission induction with FLAG.
    Leukemia, 1999, Volume: 13, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Transplantation, Homologous; Vidarabine

1999
Acute myeloid leukemia M2 and t(8;21)(q22;q22) with an unusual phenotype: myeloperoxidase (+), CD13 (-), CD14 (-), and CD33(-).
    Annals of hematology, 1999, Volume: 78, Issue:5

    Topics: Adult; Antibiotics, Antineoplastic; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antimetabolites, Antineoplastic; Bone Marrow Cells; CD13 Antigens; Cell Adhesion Molecules; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Cytarabine; Female; Flow Cytometry; Humans; Idarubicin; Immunophenotyping; Leukemia, Myeloid, Acute; Lipopolysaccharide Receptors; Male; Membrane Glycoproteins; Peroxidase; Phenotype; Sialic Acid Binding Ig-like Lectin 3; Translocation, Genetic

1999
[The use of the nucleolar apparatus indices of the leukemic cells in patients with acute myeloblastic leukemia for the early detection of resistant clones].
    Likars'ka sprava, 1999, Issue:2

    Topics: Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Carubicin; Cell Nucleolus; Cytarabine; Drug Resistance, Neoplasm; Humans; Leukemia, Myeloid, Acute; Lymphocytes; Middle Aged; Prednisolone; Time Factors

1999
De novo acute myelogenous leukemia with trilineage myelodysplasia associated with t(8;21)(q22;q22).
    Internal medicine (Tokyo, Japan), 1999, Volume: 38, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Cytarabine; Daunorubicin; Humans; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Prednisolone; Translocation, Genetic

1999
Sodium and potassium excretion changes and bone marrow recovery after chemotherapy.
    Stem cells (Dayton, Ohio), 1999, Volume: 17, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carcinoma, Small Cell; Carmustine; Cyclophosphamide; Cytarabine; Etoposide; Female; Hodgkin Disease; Humans; Leukemia, Myeloid, Acute; Lung Neoplasms; Lymphoma, Non-Hodgkin; Male; Multiple Myeloma; Potassium; Sodium

1999
Skin toxicity after administration of low-dose cytarabine.
    Medical and pediatric oncology, 1999, Volume: 33, Issue:4

    Topics: Antimetabolites, Antineoplastic; Child; Cytarabine; Erythema Nodosum; Exanthema; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Skin Diseases; Urticaria

1999
The lung resistance protein (LRP) predicts poor outcome in acute myeloid leukemia.
    Advances in experimental medicine and biology, 1999, Volume: 457

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Resistance, Multiple; Etoposide; Female; Humans; Idarubicin; Immunohistochemistry; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Proteins; Predictive Value of Tests; Prognosis; Survival Rate; Tretinoin; Vault Ribonucleoprotein Particles

1999
Comparison of BCL-2 and BAX protein expression with in vitro sensitivity to ARA-C and 6TG in AML.
    Advances in experimental medicine and biology, 1999, Volume: 457

    Topics: Apoptosis; bcl-2-Associated X Protein; Blast Crisis; Bone Marrow Cells; Cytarabine; Flow Cytometry; Humans; Immunohistochemistry; Leukemia, Myeloid, Acute; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Thioguanine

1999
In vitro cytotoxic drug activity and in vivo pharmacokinetics in childhood acute myeloid leukemia.
    Advances in experimental medicine and biology, 1999, Volume: 457

    Topics: Amsacrine; Antineoplastic Agents; Blast Crisis; Bone Marrow; Cell Survival; Child; Cytarabine; Doxorubicin; Drug Screening Assays, Antitumor; Erythrocytes; Etoposide; Humans; Leukemia, Myeloid, Acute; Recurrence; Scandinavian and Nordic Countries; Thioguanine

1999
Aphidicolin markedly increases the in vitro sensitivity to ara-C of blast cells from patients with AML.
    Advances in experimental medicine and biology, 1999, Volume: 457

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Aphidicolin; Blast Crisis; Bone Marrow Cells; Cell Survival; Cytarabine; Drug Screening Assays, Antitumor; Drug Synergism; Etoposide; Humans; Leukemia, Myeloid, Acute; Tumor Cells, Cultured

1999
Effects of CSFS and their combinations with chemotherapeutic agents (CH) on leukemic blasts (LB) in children (MTT-assay).
    Advances in experimental medicine and biology, 1999, Volume: 457

    Topics: Adolescent; Adult; Antineoplastic Agents; Blast Crisis; Bone Marrow Cells; Child; Child, Preschool; Colony-Stimulating Factors; Cytarabine; Doxorubicin; Drug Screening Assays, Antitumor; Drug Synergism; Etoposide; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Infant; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma

1999
Flow cytometric chemosensitivity analysis of blasts from patients with acute myeloblastic leukemia and myelodysplastic syndromes: the use of 7AAD with antibodies to CD45 or CD34.
    Cytometry, 1999, Dec-01, Volume: 37, Issue:4

    Topics: Antibodies; Antigens, CD34; Cell Count; Cytarabine; Dactinomycin; Flow Cytometry; Fluorescent Dyes; Humans; Leukemia, Myeloid, Acute; Leukocyte Common Antigens; Light; Myelodysplastic Syndromes; Scattering, Radiation; Sensitivity and Specificity; Stem Cells; Tumor Cells, Cultured

1999
Modulation of in vitro chemosensitivity in acute myelogenous leukemia cell line by GM-CSF: opposing effects observed with different cytotoxic drugs and time exposure.
    Leukemia research, 1999, Volume: 23, Issue:10

    Topics: Antimetabolites, Antineoplastic; Cell Death; Cytarabine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Therapy, Combination; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Methotrexate; Time Factors; Tumor Cells, Cultured

1999
[Necrotizing fasciitis in sacrococcygeal pilonidal sinus in a patient with bone marrow aplasia. Treatment by large excision and closing by local flaps].
    Annales de chirurgie plastique et esthetique, 1999, Volume: 44, Issue:5

    Topics: Adult; Anemia, Aplastic; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Cytarabine; Daunorubicin; Drug Therapy, Combination; Fasciitis, Necrotizing; Female; Humans; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Pilonidal Sinus; Sacrococcygeal Region; Surgical Flaps

1999
Pulmonary infection caused by Gymnascella hyalinospora in a patient with acute myelogenous leukemia.
    Journal of clinical microbiology, 2000, Volume: 38, Issue:1

    Topics: Adult; Amphotericin B; Antifungal Agents; Antineoplastic Agents; Ascomycota; Cytarabine; Drug Resistance, Microbial; Female; Humans; Idarubicin; Itraconazole; Leukemia, Myeloid, Acute; Lung Diseases, Fungal; Midwestern United States; Mycological Typing Techniques

2000
Extramedullary myeloid cell tumour: presentation as anterior chest wall mass during AML relapse.
    Postgraduate medical journal, 1999, Volume: 75, Issue:886

    Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Soft Tissue Neoplasms; Thoracic Neoplasms

1999
Regulation of drug sensitivity by ribosomal protein S3a.
    Blood, 2000, Feb-01, Volume: 95, Issue:3

    Topics: Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line; Cryopreservation; Cytarabine; DNA Replication; DNA, Neoplasm; Doxorubicin; Drug Resistance, Neoplasm; Gene Targeting; Humans; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Neoplasm Proteins; Neoplastic Stem Cells; Paclitaxel; Phosphorylation; Phosphoserine; Protein Processing, Post-Translational; Rats; Ribosomal Proteins; Tissue Preservation; Treatment Outcome; Tretinoin

2000
Multivariate analysis of prognostic factors in patients with refractory and relapsed acute myeloid leukemia undergoing sequential high-dose cytosine arabinoside and mitoxantrone (S-HAM) salvage therapy: relevance of cytogenetic abnormalities.
    Leukemia, 2000, Volume: 14, Issue:2

    Topics: Adult; Aged; Analysis of Variance; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Austria; Cytarabine; Disease-Free Survival; Drug Administration Schedule; Female; Germany; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Multivariate Analysis; Neoplasm, Residual; Prognosis; Prospective Studies; Recurrence; Risk Factors; Salvage Therapy; Survival Analysis; Treatment Outcome

2000
Typhlitis as a presenting manifestation of acute myelogenous leukemia.
    Southern medical journal, 2000, Volume: 93, Issue:2

    Topics: Adult; Antimetabolites, Antineoplastic; Cytarabine; Fatal Outcome; Female; Granulocyte Colony-Stimulating Factor; Humans; Ileal Diseases; Laparotomy; Leukemia, Myeloid, Acute; Tomography, X-Ray Computed

2000
[Cytoprotective effect of amifostine in children during induction therapy according to BFM-83: report on cases].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1998, Volume: 51 Suppl 4

    Topics: Amifostine; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Retrospective Studies

1998
Acute myeloblastic leukemia secondary to myelodysplasia (MDS-AML): a comparison of remission induction with three drugs versus standard two-drugs induction.
    Leukemia & lymphoma, 2000, Volume: 36, Issue:5-6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Humans; Idarubicin; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Myelodysplastic Syndromes; Remission Induction

2000
Cellular cytotoxic drug sensitivity in children with acute leukemia and Down's syndrome: an explanation to differences in clinical outcome?
    Leukemia, 2000, Volume: 14, Issue:5

    Topics: Antineoplastic Agents; Blast Crisis; Cell Survival; Child; Cytarabine; Dexamethasone; Down Syndrome; Doxorubicin; Etoposide; Humans; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Thioguanine; Treatment Outcome; Tumor Cells, Cultured

2000
Treatment of patients with recurrent and primary refractory acute myelogenous leukemia using mitoxantrone and intermediate-dose cytarabine: a pharmacologically based regimen.
    Cancer, 2000, May-01, Volume: 88, Issue:9

    Topics: Adult; Age Factors; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cause of Death; Cerebellar Diseases; Cytarabine; Death, Sudden, Cardiac; Disease-Free Survival; Drug Eruptions; Exanthema; Female; Humans; Injections, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Neoplasm Recurrence, Local; Neutropenia; Remission Induction; Thrombocytopenia; Treatment Outcome

2000
Secondary acute nonlymphocytic leukemia following successful chemotherapy combining cisplatin, doxorubicin, and cyclophosphamide for stage IV epithelial ovarian cancer.
    Archives of gynecology and obstetrics, 2000, Volume: 263, Issue:4

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bone Marrow; Cisplatin; Cyclophosphamide; Cystadenocarcinoma, Mucinous; Cytarabine; Daunorubicin; Doxorubicin; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Liver Neoplasms; Middle Aged; Mitoxantrone; Ovarian Neoplasms; Prednisolone; Remission Induction; Reoperation

2000
[Retrospective study of acute myelogenous leukemia in elderly patients: treatment and outcome of 83 consecutive patients].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2000, Volume: 41, Issue:4

    Topics: Age Factors; Aged; Aged, 80 and over; Chromosomes, Human, Pair 5; Chromosomes, Human, Pair 7; Cytarabine; Daunorubicin; Drug Therapy, Combination; Gene Deletion; Humans; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Remission Induction; Retrospective Studies; Treatment Outcome; Tretinoin

2000
Low-dose cytarabine and aclarubicin in combination with granulocyte colony-stimulating factor (CAG regimen) for previously treated patients with relapsed or primary resistant acute myelogenous leukemia (AML) and previously untreated elderly patients with
    International journal of hematology, 2000, Volume: 71, Issue:3

    Topics: Aclarubicin; Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Lymphocyte Activation; Male; Neoplasms, Second Primary; Survival Rate; Treatment Outcome

2000
Do de novo acute myeloid leukemias with normal cytogenetics involve two main prognostic categories distinguished by the presence of erythroblastic and/or megakaryocytic dysplasia?
    Neoplasma, 2000, Volume: 47, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Administration Schedule; Erythroblasts; Female; Humans; Karyotyping; Leukemia, Myeloid, Acute; Male; Megakaryocytes; Middle Aged; Prognosis; Treatment Outcome

2000
Lung toxicity following fludarabine, cytosine arabinoside and mitoxantrone (flan) treatment for acute leukemia.
    Haematologica, 2000, Volume: 85, Issue:7

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Hemorrhage; Humans; Infant, Newborn; Leukemia; Leukemia, Myeloid, Acute; Lung Diseases; Male; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Respiratory Distress Syndrome, Newborn; Staphylococcal Infections; Vidarabine

2000
[In vitro growth and clinical response of leukemia cells to macrophage colony-stimulating factor (M-CSF) and granulocyte colony-stimulating factor (G-CSF) in acute leukemia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Macrophage Colony-Stimulating Factor; Male; Middle Aged; Myelodysplastic Syndromes; Tumor Cells, Cultured

2000
Enhancement of cytosine arabinoside-induced apoptosis in human myeloblastic leukemia cells by NF-kappa B/Rel- specific decoy oligodeoxynucleotides.
    Gene therapy, 2000, Volume: 7, Issue:14

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Cytarabine; Genes, rel; Humans; Leukemia, Myeloid, Acute; NF-kappa B; Oligodeoxyribonucleotides; Tumor Cells, Cultured

2000
[Study on combined chemosensitivity test in acute non-lymphocytic leukemia].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 1998, Volume: 19, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Harringtonines; Homoharringtonine; Humans; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Tumor Cells, Cultured

1998
Acute myeloblastic leukemic cells acquire cellular cytotoxicity under genotoxic stress: implication of granzyme B and perforin.
    Blood, 2000, Sep-01, Volume: 96, Issue:5

    Topics: Antigens, CD34; Antineoplastic Agents; Cell Survival; Coumarins; Cytarabine; Cytotoxicity Tests, Immunologic; Daunorubicin; DNA, Antisense; Edetic Acid; Etoposide; Flow Cytometry; Granzymes; HeLa Cells; Humans; Isocoumarins; Jurkat Cells; K562 Cells; Leukemia, Myeloid, Acute; Magnesium Chloride; Membrane Glycoproteins; Perforin; Pore Forming Cytotoxic Proteins; Serine Endopeptidases; Tumor Cells, Cultured; U937 Cells

2000
No impact of high-dose cytarabine on the outcome of patients transplanted for acute myeloblastic leukaemia in first remission. Acute Leukaemia Working Party of the European Group for Blood and Marrow Transplantation (EBMT).
    British journal of haematology, 2000, Volume: 110, Issue:2

    Topics: Adolescent; Adult; Age Factors; Aged; Antimetabolites, Antineoplastic; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Disease-Free Survival; Female; Hematopoietic Stem Cell Transplantation; Humans; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Regression Analysis; Retrospective Studies; Transplantation, Autologous; Transplantation, Homologous; Treatment Outcome

2000
Visual loss following high-dose cytosine arabinoside (ARA-C)
    European journal of haematology, 2000, Volume: 64, Issue:3

    Topics: Adult; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Nervous System Diseases; Vision Disorders

2000
Treatment of childhood acute myelogenous leukemia with an intensive regimen (AML-87) that individualizes etoposide and cytarabine dosages: short- and long-term effects.
    Leukemia, 2000, Volume: 14, Issue:10

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Dose-Response Relationship, Drug; Etoposide; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Treatment Outcome

2000
[Childhood acute myeloblastic leukemias. Report of 21 cases].
    La Tunisie medicale, 2000, Volume: 78, Issue:3

    Topics: Adolescent; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Male; Prognosis; Remission Induction; Retrospective Studies; Survival Analysis

2000
High dose ara-C combined with autologous peripheral blood stem cell transplantation in the treatment of acute myelogenous leukemia: the question is still not answered.
    Stem cells (Dayton, Ohio), 2000, Volume: 18, Issue:6

    Topics: Antimetabolites, Antineoplastic; Combined Modality Therapy; Cytarabine; Dose-Response Relationship, Drug; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Transplantation, Autologous

2000
Long-term survival after induction therapy with idarubicin and cytosine arabinoside for de novo acute myeloid leukemia.
    Annals of hematology, 2000, Volume: 79, Issue:10

    Topics: Acute Disease; Adolescent; Adult; Aged; Cytarabine; Disease-Free Survival; Female; Humans; Idarubicin; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Multivariate Analysis; Remission Induction; Survival Rate

2000
Contrasting in vitro effects for the combination of fludarabine, cytosine arabinoside (Ara-C) and granulocyte colony-stimulating factor (FLAG) compared with daunorubicin and Ara-C in P-glycoprotein-positive and P-glycoprotein-negative acute myeloblastic l
    British journal of haematology, 2000, Volume: 111, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B; Cell Death; Clone Cells; Cytarabine; Daunorubicin; Drug Resistance, Multiple; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Remission Induction; Vidarabine

2000
Serum LDH, a prognostic factor in elderly patients with acute myelogenous leukaemia.
    British journal of cancer, 2001, Jan-05, Volume: 84, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cytarabine; Follow-Up Studies; Humans; L-Lactate Dehydrogenase; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Multivariate Analysis

2001
Madurella infection in an immunocompromised host.
    International journal of dermatology, 2000, Volume: 39, Issue:12

    Topics: Aged; Antifungal Agents; Antimetabolites, Antineoplastic; Cytarabine; Humans; Immunocompromised Host; Itraconazole; Leukemia, Myeloid, Acute; Madurella; Male; Mycetoma

2000
Isodicentric 7p, idic(7)(q11.2), in acute myeloid leukemia associated with older age and favorable response to induction chemotherapy: a new clinical entity?
    Genes, chromosomes & cancer, 2001, Volume: 30, Issue:3

    Topics: Aged; Aged, 80 and over; Aging; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chromosome Banding; Chromosomes, Human, Pair 7; Cytarabine; Female; Humans; Idarubicin; In Situ Hybridization, Fluorescence; Isochromosomes; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Male; Remission Induction; Thioguanine

2001
[Outcome of autologous bone marrow transplantation in 73 patients with acute leukemia].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 1998, Volume: 19, Issue:8

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Melphalan; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Transplantation Conditioning; Transplantation, Autologous; Treatment Outcome

1998
[Outcome of acute myelogenous leukemia in 41 patients treated with idarubicin: the prognosis of t(8;21) cases].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2001, Volume: 42, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; CD56 Antigen; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Cytarabine; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Survival Analysis; Treatment Outcome

2001
Circumvention of ara-C resistance by aphidicolin in blast cells from patients with AML.
    British journal of cancer, 2001, Mar-02, Volume: 84, Issue:5

    Topics: Antimetabolites, Antineoplastic; Aphidicolin; Cell Survival; Cytarabine; DNA; Drug Resistance; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Fetal Blood; Formazans; Humans; Lethal Dose 50; Leukemia, Myeloid, Acute; Tetrazolium Salts; Tumor Cells, Cultured

2001
Total body irradiation before allogeneic bone marrow transplantation: is more dose better?
    International journal of radiation oncology, biology, physics, 2001, Mar-15, Volume: 49, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radiation-Sensitizing Agents; Radiotherapy Dosage; Retrospective Studies; Thiotepa; Transplantation Conditioning; Transplantation, Homologous; Whole-Body Irradiation

2001
2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine: a novel anticancer nucleoside analog that causes both DNA strand breaks and G(2) arrest.
    Molecular pharmacology, 2001, Volume: 59, Issue:4

    Topics: Antineoplastic Agents; CDC2 Protein Kinase; Chromosome Breakage; Cyclin B; Cyclin B1; Cytarabine; Deoxycytidine; DNA, Neoplasm; G2 Phase; Gemcitabine; Humans; Leukemia, Myeloid, Acute; Lymphocytes; Phosphorylation; RNA; Tumor Cells, Cultured

2001
[All-trans retinoic acid combined with low-dose cytosine arabinoside treatment for acute myelogenous leukemia with trilineage myelodysplasia--a case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2001, Volume: 28, Issue:3

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Middle Aged; Neural Tube Defects; Tretinoin

2001
Topoisomerase II inhibitor induced leukemia in a patient with AIDS.
    AIDS (London, England), 2001, Feb-16, Volume: 15, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Homosexuality, Male; Humans; Idarubicin; Leukemia, Myeloid, Acute; Lymphoma, AIDS-Related; Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Neoplasm Metastasis; Neoplasms, Second Primary; Topoisomerase II Inhibitors

2001
Acute myeloid leukemia cells are protected from spontaneous and drug-induced apoptosis by direct contact with a human bone marrow stromal cell line (HS-5).
    Experimental hematology, 2001, Volume: 29, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Bone Marrow Cells; Cell Cycle; Cell Division; Coculture Techniques; Colony-Forming Units Assay; Culture Media, Conditioned; Cytarabine; Daunorubicin; Flow Cytometry; Humans; Leukemia, Myeloid, Acute; Leukocyte Common Antigens; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-bcl-2; Stromal Cells; Tumor Cells, Cultured

2001
Cell cycle regulatory protein expression in fresh acute myeloid leukemia cells and after drug exposure.
    Leukemia, 2001, Volume: 15, Issue:4

    Topics: Apoptosis; CDC2-CDC28 Kinases; Cell Cycle Proteins; Cyclin D; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cyclins; Cytarabine; Daunorubicin; DNA Damage; Humans; Interleukin-3; Leukemia, Myeloid, Acute; Microtubule-Associated Proteins; Protein Serine-Threonine Kinases; Retinoblastoma Protein; Stem Cell Factor; Tumor Suppressor Proteins

2001
Absence of mutations in the deoxycytidine kinase (dCK) gene in patients with relapsed and/or refractory acute myeloid leukemia (AML).
    Leukemia, 2001, Volume: 15, Issue:5

    Topics: Cytarabine; Deoxycytidine Kinase; Drug Resistance, Neoplasm; Humans; Leukemia, Myeloid, Acute; Mutation; Recurrence

2001
Monitoring of intracellular 1-beta-D-arabinofuranosylcytosine 5'-triphosphate in 1-beta-D-arabinofuranosylcytosine therapy at low and conventional doses.
    Japanese journal of cancer research : Gann, 2001, Volume: 92, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Arabinofuranosylcytosine Triphosphate; Cytarabine; Female; Half-Life; Humans; Infusions, Intravenous; Injections, Subcutaneous; Kinetics; Leukemia, Myeloid, Acute; Male; Middle Aged

2001
Permanent cerebellar toxicity of cytosine arabinoside (Ara C) in a young woman.
    Movement disorders : official journal of the Movement Disorder Society, 2001, Volume: 16, Issue:3

    Topics: Adult; Antimetabolites, Antineoplastic; Atrophy; Cerebellar Ataxia; Cerebellum; Cytarabine; Female; Humans; Injections, Spinal; Leukemia, Myeloid, Acute; Magnetic Resonance Imaging; Videotape Recording

2001
Leukemia cutis in an elderly patient treated with low dose cytosine arabinoside and etoposide.
    Leukemia & lymphoma, 2001, Volume: 40, Issue:3-4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Etoposide; Exanthema; Humans; Immunophenotyping; Leukemia; Leukemia, Myeloid, Acute; Male

2001
[Primary pulmonary manifestation of extramedullary acute myelocytic leukemia].
    Pneumologie (Stuttgart, Germany), 2001, Volume: 55, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Bronchoalveolar Lavage Fluid; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Lung Neoplasms; Middle Aged; Prednisolone; Radiography; Thioguanine; Vincristine

2001
Effect of simvastatin alone and in combination with cytosine arabinoside on the proliferation of myeloid leukemia cell lines.
    Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 2001, Volume: 49, Issue:4

    Topics: Anticholesteremic Agents; Antimetabolites, Antineoplastic; Cell Division; Cytarabine; Drug Synergism; HL-60 Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leukemia, Myeloid, Acute; Simvastatin; Tumor Cells, Cultured; Tumor Stem Cell Assay

2001
Cost of de novo acute myeloid leukemia induction therapy in adults: analysis of EORTC-GIMEMA AML10 and FLANG regimens.
    Journal of experimental & clinical cancer research : CR, 2001, Volume: 20, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Costs and Cost Analysis; Cytarabine; Drug Costs; Drug Synergism; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Maximum Tolerated Dose; Middle Aged; Mitoxantrone; Prognosis; Survival Analysis; Treatment Outcome; Vidarabine

2001
Successful salvage of RAEB/AML relapsing early post allograft with FLAG-Ida conditioned mini-allograft: a report of two cases.
    Clinical and laboratory haematology, 2001, Volume: 23, Issue:2

    Topics: Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Leukemia, Myeloid, Acute; Middle Aged; Recombinant Proteins; Recurrence; Salvage Therapy; Transplantation, Homologous; Vidarabine

2001
Impact of treatment on the outcome of acute myeloid leukemia with inversion 16: a single institution's experience.
    Leukemia, 2001, Volume: 15, Issue:9

    Topics: Acute Disease; Adolescent; Antineoplastic Agents; Bone Marrow Transplantation; Child; Child, Preschool; Chromosome Inversion; Chromosomes, Human, Pair 16; Cladribine; Combined Modality Therapy; Cytarabine; Drug Therapy, Combination; Etoposide; Female; Humans; Infant; Leukemia, Megakaryoblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Male; Prognosis; Treatment Outcome

2001
Therapeutic targeting of the MEK/MAPK signal transduction module in acute myeloid leukemia.
    The Journal of clinical investigation, 2001, Volume: 108, Issue:6

    Topics: Apoptosis; Benzamides; Cell Cycle; Cell Cycle Proteins; Cell Division; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Cytarabine; Enzyme Inhibitors; Flavonoids; Humans; Leukemia, Myeloid, Acute; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Proteins; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Tumor Cells, Cultured; Tumor Suppressor Proteins; X-Linked Inhibitor of Apoptosis Protein

2001
[CD7(+) acute myeloid leukemia (M0) associated with a mediastinal bulky mass lesion].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2001, Volume: 42, Issue:8

    Topics: Adult; Antigens, CD7; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Diagnosis, Differential; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Mediastinal Neoplasms; Neoplasms, Multiple Primary; Remission Induction

2001
[Therapy of acute myeloid leukemia in the elderly patient].
    Zeitschrift fur Gerontologie und Geriatrie, 2001, Volume: 34, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Geriatric Assessment; Germany; Humans; Infant; Leukemia, Myeloid, Acute; Middle Aged; Remission Induction; Survival Rate

2001
[Experimental study of cord blood plasma enhancing the anti-leukemia effect of Ara-C].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 1999, Volume: 20, Issue:5

    Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Cell Cycle; Cytarabine; Drug Resistance, Neoplasm; Female; Fetal Blood; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Plasma; Recombinant Proteins; Tumor Cells, Cultured

1999
Severe alveolar proteinosis following chemotherapy for acute myeloid leukemia in a lung allograft recipient.
    Journal of thoracic imaging, 2001, Volume: 16, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Diagnosis, Differential; Fatal Outcome; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Pulmonary Alveolar Proteinosis; Tomography, X-Ray Computed; Vidarabine

2001
Cocaine-contaminated allogeneic bone marrow transplantation.
    Acta haematologica, 2001, Volume: 106, Issue:3

    Topics: Anemia, Hemolytic, Autoimmune; Antineoplastic Combined Chemotherapy Protocols; Autoimmune Diseases; Bone Marrow Transplantation; Cocaine-Related Disorders; Cytarabine; Daunorubicin; Disease Progression; Fatal Outcome; Female; Graft Survival; Humans; Immunosuppression Therapy; Leukemia, Myeloid, Acute; Male; Marijuana Abuse; Middle Aged; Recurrence; Salvage Therapy; Thrombocythemia, Essential; Tissue and Organ Procurement; Tissue Donors; Transplantation, Homologous

2001
And the sun keeps shining.
    The Journal of pediatrics, 2001, Volume: 139, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Cytarabine; Etoposide; Female; Hair Follicle; Humans; Idarubicin; Leukemia, Myeloid, Acute

2001
Effects of signal transduction inhibitor 571 in acute myelogenous leukemia cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:12

    Topics: Benzamides; Cell Division; Cytarabine; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Imatinib Mesylate; Interleukin-3; Kinetics; Leukemia, Myeloid, Acute; Leukocyte Count; Phosphorylation; Piperazines; Proto-Oncogene Proteins c-kit; Pyrimidines; Recurrence; Signal Transduction; Stem Cell Factor

2001
Idarubicin, cytarabine, and topotecan in patients with refractory or relapsed acute myelogenous leukemia and high-risk myelodysplastic syndrome.
    American journal of hematology, 2001, Volume: 68, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Remission Induction; Salvage Therapy; Survival Rate; Topotecan; Treatment Outcome

2001
Different drug sensitivity profiles of acute myeloid and lymphoblastic leukemia and normal peripheral blood mononuclear cells in children with and without Down syndrome.
    Blood, 2002, Jan-01, Volume: 99, Issue:1

    Topics: Amsacrine; Anthracyclines; Antineoplastic Agents; Busulfan; Cell Survival; Child; Child, Preschool; Cytarabine; Down Syndrome; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Etoposide; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Thioguanine; Vincristine

2002
Novel triterpenoid CDDO-Me is a potent inducer of apoptosis and differentiation in acute myelogenous leukemia.
    Blood, 2002, Jan-01, Volume: 99, Issue:1

    Topics: Annexin A5; Apoptosis; bcl-2-Associated X Protein; Blast Crisis; Caspase 3; Caspases; Cell Differentiation; Cell Survival; Cytarabine; DNA Fragmentation; Drug Interactions; Flow Cytometry; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Membrane Potentials; Mitogen-Activated Protein Kinases; Oleanolic Acid; Phosphorylation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Retinoids; Tretinoin; Tumor Cells, Cultured

2002
Effects of cytarabine and various anthracyclins on platelet activation: characterization of in vitro effects and their possible clinical relevance in acute myelogenous leukemia.
    International journal of cancer, 2002, Jan-01, Volume: 97, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antigens, CD; Antimetabolites, Antineoplastic; Cell Adhesion; Cytarabine; Dose-Response Relationship, Drug; Female; Flow Cytometry; Humans; Leukemia, Myeloid, Acute; Leukocytes; Male; Middle Aged; Neoplastic Cells, Circulating; P-Selectin; Platelet Activation; Platelet Membrane Glycoproteins; Tetraspanin 30; Tumor Cells, Cultured

2002
CD56 expression in myeloperoxidase-negative FAB M5 acute myeloid leukemia.
    American journal of hematology, 2002, Volume: 69, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bone Marrow Transplantation; CD56 Antigen; Chromosome Aberrations; Chromosomes, Human, Pair 11; Cytarabine; Fatal Outcome; Female; Humans; Immunophenotyping; In Situ Hybridization, Fluorescence; Leukemia, Myeloid, Acute; Male; Middle Aged; Peroxidase; Recurrence; Remission Induction

2002
Autologous stem cell transplantation for advanced acute myeloid leukemia.
    Bone marrow transplantation, 2002, Volume: 29, Issue:4

    Topics: Adult; Aged; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cell Count; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Cytarabine; Cytogenetics; Disease-Free Survival; Etoposide; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Middle Aged; Prognosis; Translocation, Genetic; Transplantation, Autologous

2002
Herpesvirus-6 encephalitis complicated by Wernicke-Korsakoff syndrome in a pediatric recipient of unrelated cord blood transplantation.
    Journal of pediatric hematology/oncology, 2001, Volume: 23, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Child; Combined Modality Therapy; Cytarabine; Daunorubicin; Encephalitis, Viral; Etoposide; Fatal Outcome; Female; Fetal Blood; Foscarnet; Ganciclovir; Hematopoietic Stem Cell Transplantation; Herpesvirus 6, Human; Humans; Immunocompromised Host; Korsakoff Syndrome; Leukemia, Myeloid, Acute; Recurrence; Roseolovirus Infections; Transplantation Conditioning; Transplantation, Homologous; Virus Activation

2001
Treatment and outcome of infants with acute myeloid leukemia.
    Blood, 2002, Apr-01, Volume: 99, Issue:7

    Topics: Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Humans; Infant; Leukemia, Myeloid, Acute; Survival Rate; Time Factors; Treatment Outcome

2002
A case of zygomycosis and invasive candidiasis involving the epiglottis and tongue in an immunocompromised patient.
    Scandinavian journal of infectious diseases, 2002, Volume: 34, Issue:2

    Topics: Adult; Amphotericin B; Antifungal Agents; Antineoplastic Agents; Candida; Candidiasis; Cytarabine; Epiglottis; Fungi; Humans; Idarubicin; Immunocompromised Host; Leukemia, Myeloid, Acute; Male; Neutropenia; Tongue; Tongue Diseases; Zygomycosis

2002
Cutaneous pleomorphic T-cell lymphoma coexisting with myelodysplastic syndrome transforming into acute myeloid leukemia: successful treatment with a fludarabine-containing regimen.
    European journal of haematology, 2002, Volume: 68, Issue:1

    Topics: Aged; Anemia, Refractory, with Excess of Blasts; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Contraindications; Cytarabine; Disease Progression; Granulocyte Colony-Stimulating Factor; Humans; Immunophenotyping; Leukemia, Myeloid, Acute; Lymphoma, T-Cell, Cutaneous; Male; Methotrexate; Neoplasms, Second Primary; Remission Induction; Skin Neoplasms; Vidarabine

2002
[Intermediate doses of cytosine arabinoside in the treatment of acute non-lymphoblastic leukaemia in children].
    Medycyna wieku rozwojowego, 2000, Volume: 4, Issue:1 Suppl 2

    Topics: Adolescent; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Male; Poland; Prednisone; Remission Induction; Retrospective Studies; Risk Factors; Severity of Illness Index; Survival Analysis; Treatment Outcome; Vincristine

2000
Bone marrow transplantation in acute leukemia using intensive chemoradiotherapy (SCARI--UCLA).
    Transplantation proceedings, 1976, Volume: 8, Issue:4

    Topics: ABO Blood-Group System; Adolescent; Adult; Bone Marrow Cells; Bone Marrow Transplantation; Candidiasis; Child; Cyclophosphamide; Cytarabine; Cytomegalovirus Infections; Daunorubicin; Graft vs Host Reaction; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Middle Aged; Radiation Chimera; Thioguanine; Transplantation, Homologous

1976
Bone marrow transplantation with intensive combination chemotherapy/radiation therapy (SCARI) in acute leukemia.
    Annals of internal medicine, 1977, Volume: 86, Issue:2

    Topics: Adolescent; Adult; Bone Marrow Cells; Bone Marrow Transplantation; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Graft vs Host Reaction; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Thioguanine; Time Factors; Transplantation, Homologous

1977
"Pure" monocytic or histiomonocytic leukemia: a revised concept.
    Cancer, 1975, Volume: 35, Issue:1

    Topics: Adolescent; Adult; Aged; Alkaline Phosphatase; Bone Marrow; Bone Marrow Cells; Child, Preschool; Cytarabine; Doxorubicin; Esterases; Female; Glucuronidase; Histiocytes; Histocytochemistry; Humans; Infant; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Microscopy, Electron; Monocytes; Peroxidases; Prednisone; Remission, Spontaneous; Staining and Labeling; Vincristine

1975
Bone-marrow-profileration patterns in acute myeloblastic leukaemia determined by pulse cytophotometry.
    Lancet (London, England), 1975, Mar-15, Volume: 1, Issue:7907

    Topics: Autoradiography; Bone Marrow; Bone Marrow Cells; Cell Count; Cell Division; Cytarabine; Daunorubicin; DNA, Neoplasm; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Photometry; Remission, Spontaneous; Thioguanine; Tritium

1975
Deoxycytidine kinase: properties of the enzyme from human leukemic granulocytes.
    Blood, 1975, Volume: 46, Issue:5

    Topics: Azacitidine; Blood Proteins; Cell Separation; Cell-Free System; Cytarabine; Cytidine Deaminase; Deoxycytidine; Granulocytes; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Molecular Weight; Phosphates; Phosphotransferases; Tissue Extracts; Uridine Kinase

1975
Quality and quantity of survival in acute myeloid leukaemia.
    Lancet (London, England), 1975, Oct-04, Volume: 2, Issue:7936

    Topics: Acute Disease; Adolescent; Adult; Aged; Allopurinol; Bacterial Infections; Cytarabine; Daunorubicin; Drug Therapy, Combination; Focal Infection, Dental; Follow-Up Studies; Humans; Length of Stay; Leukemia, Myeloid, Acute; Mercaptopurine; Middle Aged; Philosophy; Quality of Life; Remission, Spontaneous

1975
[Problems in maintenance therapy in acute myeloid leukemias in adults].
    Folia haematologica (Leipzig, Germany : 1928), 1975, Volume: 102, Issue:6

    Topics: Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Remission, Spontaneous; Vincristine

1975
Symptomatic hypophosphatemia secondary to 5-azacytidine therapy of acute nonlymphocytic leukemia.
    Cancer treatment reports, 1976, Volume: 60, Issue:9

    Topics: Adult; Azacitidine; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Phosphates; Prednisone; Pregnancy; Pregnancy Complications; Thioguanine; Vincristine

1976
High remission-induction rate in acute myeloid leukaemia.
    Lancet (London, England), 1977, Mar-05, Volume: 1, Issue:8010

    Topics: Administration, Oral; Adult; Age Factors; Aged; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Injections, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission, Spontaneous; Thioguanine; Time Factors

1977
Chemotherapeutic remissions in Wistar Furth rat acute myelogenous leukemia: a model for human AML.
    Acta haematologica, 1977, Volume: 57, Issue:4

    Topics: Animals; Antineoplastic Agents; Busulfan; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Dexamethasone; Disease Models, Animal; Doxorubicin; Leukemia, Experimental; Leukemia, Myeloid, Acute; Methotrexate; Rats; Remission, Spontaneous; Vinblastine; Vincristine

1977
Deoxycytidine and lethal doses of cytarabine in advanced murine leukaemia.
    Lancet (London, England), 1977, May-14, Volume: 1, Issue:8020

    Topics: Administration, Oral; Animals; Cytarabine; Deoxycytidine; Drug Antagonism; Drug Therapy, Combination; Female; Injections, Intraperitoneal; Leukemia L1210; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mice

1977
Prolonged maintained remissions of adult acute non-lymphocytic leukaemia.
    Lancet (London, England), 1977, Jul-23, Volume: 2, Issue:8030

    Topics: Administration, Oral; Adolescent; Adult; Aged; Cytarabine; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Injections, Intramuscular; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission, Spontaneous; Thioguanine; Time Factors

1977
Separation of leukemic cells into proliferative and quiescent subpopulations by centrifugal elutriation.
    Cancer research, 1977, Volume: 37, Issue:11

    Topics: Azacitidine; Bone Marrow; Cell Division; Cell Separation; Centrifugation; Cytarabine; Humans; In Vitro Techniques; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Thymidine

1977
Prediction of therapeutic response in acute leukaemia.
    Lancet (London, England), 1978, Jan-14, Volume: 1, Issue:8055

    Topics: Adult; Aged; Cells, Cultured; Cyclophosphamide; Cytarabine; Depression, Chemical; Drug Therapy, Combination; Female; Humans; In Vitro Techniques; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Prognosis; Remission, Spontaneous; Thymidine; Tritium; Vincristine

1978
D.A.T. (daunorubicin, cytarabine, 6-thioguanine) in acute myeloid leukaemia.
    Lancet (London, England), 1978, Jun-24, Volume: 1, Issue:8078

    Topics: Aged; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Remission, Spontaneous; Thioguanine

1978
Evaluation of cyclocytidine in children with advanced acute leukemia and solid tumors.
    Cancer treatment reports, 1979, Volume: 63, Issue:8

    Topics: Adolescent; Ancitabine; Child; Child, Preschool; Cytarabine; Drug Evaluation; Humans; Infant; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Neoplasms

1979
The nature of remission in acute myeloblastic leukaemia.
    Lancet (London, England), 1979, Sep-29, Volume: 2, Issue:8144

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; BCG Vaccine; Bone Marrow; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Remission, Spontaneous; Thioguanine; Transplantation, Homologous

1979
Synchronisation of cell phase in treatment of leukaemia.
    Lancet (London, England), 1977, Sep-10, Volume: 2, Issue:8037

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Cytological Techniques; Doxorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; S Phase

1977
Acute eosinophilic leukemia. An ultrastructural study.
    Virchows Archiv. B, Cell pathology, 1978, May-19, Volume: 27, Issue:3

    Topics: Adult; Bone Marrow; Cytarabine; Daunorubicin; Eosinophils; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Prednisone; Recurrence

1978
A 13-years remission in chronic myelocytic leukemia after a single course of busulfan.
    Acta haematologica, 1978, Volume: 59, Issue:6

    Topics: Adult; Busulfan; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Remission, Spontaneous; Time Factors

1978
[Low-dose cytosine arabinoside in the therapy of varicella in childhood leukaemia (author's transl)].
    Haematologica, 1978, Volume: 63, Issue:5

    Topics: Chickenpox; Child; Cytarabine; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute

1978
Drug-induced kinetic perturbations of the marrow blasts in acute leukemia. Effects of the daunorubicin, cytosine arabinoside and 6-thioguanine combination.
    Acta haematologica, 1979, Volume: 61, Issue:5

    Topics: Adolescent; Adult; Bone Marrow; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitotic Index; Thioguanine

1979
Oscillations of marrow culture growth in acute myeloid leukemia during remission induction and remission.
    Acta haematologica, 1979, Volume: 62, Issue:5-6

    Topics: Adult; Bone Marrow; Colony-Forming Units Assay; Culture Techniques; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisone; Thioguanine

1979
[Statistical studies on therapy of leukemia with tumor formation (author's transl)].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1975, Volume: 16, Issue:1

    Topics: Adolescent; Adult; Cytarabine; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisolone; Statistics as Topic; Vincristine; Zinostatin

1975
Technique for preclinical evaluation of continuous infusion chemotherapy with the use of WF rat acute myelogenous leukemia.
    Journal of the National Cancer Institute, 1979, Volume: 62, Issue:5

    Topics: Animals; Antineoplastic Agents; Cytarabine; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Infusions, Parenteral; Injections, Intravenous; Leukemia, Experimental; Leukemia, Myeloid, Acute; Rats; Rats, Inbred WF; Thymidine; Zinostatin

1979
Studies on mechanisms of resistance to cytosine arabinoside: problems in the determination of related enzyme activities in leukemic cells.
    Annals of the New York Academy of Sciences, 1975, Aug-08, Volume: 255

    Topics: Bone Marrow; Bone Marrow Cells; Cytarabine; Cytidine Deaminase; Deoxycytidine; Drug Resistance; Erythrocytes; Granulocytes; Humans; Kinetics; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Nucleoside Deaminases; Phosphotransferases; Tetrahydrouridine

1975
Pyrimidine nucleoside monophosphate kinase from human leukemic blast cells.
    Cancer research, 1978, Volume: 38, Issue:3

    Topics: Animals; Cell Line; Cytarabine; Deoxycytidine Monophosphate; Humans; In Vitro Techniques; Kinetics; Leukemia, Experimental; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Molecular Weight; Nucleoside-Phosphate Kinase; Phosphotransferases; Pyrimidine Nucleotides; Sulfhydryl Reagents

1978
Long-term remission from acute myelogenous leukemia after bone marrow transplantation and recovery from acute graft-versus-host reaction and prolonged immunoincompetence.
    Blood, 1975, Volume: 45, Issue:2

    Topics: ABO Blood-Group System; Adolescent; Adult; Anti-Bacterial Agents; Antilymphocyte Serum; B-Lymphocytes; Bacterial Infections; Blood Group Incompatibility; Bone Marrow Cells; Bone Marrow Transplantation; Candidiasis; Cyclophosphamide; Cytarabine; Graft vs Host Reaction; Histocompatibility Antigens; Humans; Immunity, Maternally-Acquired; Immunologic Deficiency Syndromes; Leukemia, Myeloid, Acute; Male; Nitrosourea Compounds; Opsonin Proteins; T-Lymphocytes; Thioguanine; Transplantation, Homologous; Virus Diseases

1975
Successful treatment of acute leukemia during pregnancy. Combination therapy in the third trimester.
    Archives of internal medicine, 1977, Volume: 137, Issue:1

    Topics: Adult; Birth Weight; Cytarabine; Drug Therapy, Combination; Female; Humans; Infant, Newborn; Karyotyping; Leukemia, Myeloid, Acute; Prednisone; Pregnancy; Pregnancy Complications, Hematologic; Pregnancy Trimester, Third; Remission, Spontaneous; Vincristine

1977
Current concepts in acute leukemia.
    Postgraduate medicine, 1977, Volume: 61, Issue:1

    Topics: Acute Disease; Adult; Age Factors; BCG Vaccine; Cytarabine; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Humans; Leukemia; Leukemia, Myeloid, Acute; Middle Aged; Prednisone; Vincristine

1977
[Induction and maintenance treatment of acute myelogenous leukemia in adults by sequential use of combination chemotherapy (author's transl)].
    Medizinische Klinik, 1977, Apr-15, Volume: 72, Issue:15

    Topics: Adult; Aged; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Remission, Spontaneous; Thioguanine; Time Factors; Vincristine

1977
Remission maintenance therapy in acute myelogenous leukemia.
    The Western journal of medicine, 1977, Volume: 126, Issue:4

    Topics: Adolescent; Adult; Aged; Cytarabine; Humans; Leukemia, Myeloid, Acute; Middle Aged; Remission, Spontaneous; Thioguanine

1977
Pharmacokinetics of cytosine arabinoside in acute myeloid leukemia.
    Clinical pharmacology and therapeutics, 1977, Volume: 21, Issue:6

    Topics: Adult; Aged; Cytarabine; Deamination; Female; Glomerular Filtration Rate; Humans; Infusions, Parenteral; Injections, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged

1977
A case of acute myeloblastic leukemia with Ph1 chromosome showing translocation 9q+;22q-.
    Blood, 1977, Volume: 50, Issue:2

    Topics: Chromosome Aberrations; Chromosomes, Human, 21-22 and Y; Chromosomes, Human, 6-12 and X; Cytarabine; Humans; Japan; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Nuclear Warfare; Prednisolone; Translocation, Genetic

1977
Multiple-drug chemotherapy for acute leukemia The TRAMPCOL regimen: results in 86 patients.
    Cancer, 1977, Volume: 40, Issue:1

    Topics: Adolescent; Asparaginase; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Methotrexate; Prednisolone; Remission, Spontaneous; Thioguanine; Vincristine

1977
Potential advances in the clinical use of arabinosyl cytosine.
    Cancer treatment reports, 1977, Volume: 61, Issue:4

    Topics: Adult; Cytarabine; Delayed-Action Preparations; Drug Resistance; Humans; In Vitro Techniques; Infusions, Parenteral; Leukemia, Myeloid, Acute; Tetrahydrouridine

1977
Prolonged remission maintenance in acute myeloid leukaemia.
    British medical journal, 1977, Aug-27, Volume: 2, Issue:6086

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisolone; Remission, Spontaneous; Thioguanine; Vincristine

1977
Pharmacologic studies of continuous infusion of arabinosylcytosine by liquid infusion system.
    Clinical pharmacology and therapeutics, 1977, Volume: 22, Issue:3

    Topics: Arabinofuranosyluracil; Cytarabine; Humans; Infusions, Parenteral; Leukemia, Myeloid, Acute; Methods

1977
Prolonged remission of leukemia associated with polycythemia vera.
    Cancer, 1977, Volume: 40, Issue:3

    Topics: Aged; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Male; Polycythemia Vera; Prednisone; Remission, Spontaneous; Time Factors; Vincristine

1977
Cytosine arabinoside and 6-thioguanine in the treatment of childhood acute myeloblastic leukemia.
    Cancer, 1977, Volume: 40, Issue:3

    Topics: Adolescent; Brain Neoplasms; Child; Child, Preschool; Cytarabine; Drug Therapy, Combination; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Pregnancy; Pregnancy Complications, Hematologic; Prospective Studies; Recurrence; Remission, Spontaneous; Thioguanine; Time Factors

1977
Blast crisis of chronic granulocytic leukemia. Morphologic variants and therapeutic implications.
    The American journal of medicine, 1977, Volume: 63, Issue:4

    Topics: Adult; Bone Marrow; Carmustine; Cytarabine; Diploidy; Drug Therapy, Combination; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphocytes; Male; Maryland; Middle Aged; Prednisone; Retrospective Studies; Splenectomy; Vincristine

1977
Assessment of drug sensitivity of human leukaemic myeloblasts. II. The toxic effects of cytosine arabinoside on 125IUdR-labelled human leukaemic myeloblasts in mice.
    British journal of cancer, 1977, Volume: 36, Issue:3

    Topics: Animals; Blood Cells; Bone Marrow Cells; Cell Survival; Cells, Cultured; Cytarabine; Drug Evaluation, Preclinical; Drug Resistance; Humans; Leukemia, Myeloid, Acute; Mice

1977
Acute myelogenous leukemia as a late complication of the multimodality therapy for Hodgkin's disease.
    The Johns Hopkins medical journal, 1977, Volume: 141, Issue:5

    Topics: Adult; Biopsy; Bone Marrow; Cytarabine; Daunorubicin; Hodgkin Disease; Humans; Leukemia, Myeloid, Acute; Leukemia, Radiation-Induced; Male; Mechlorethamine; Prednisone; Procarbazine; Radiotherapy; Thrombocytopenia; Vinblastine; Vincristine

1977
[Treatment of acute myelogenous leukemia in adults; an account of the years 1968 to 1975].
    Nederlands tijdschrift voor geneeskunde, 1977, Nov-12, Volume: 121, Issue:46

    Topics: Adolescent; Adult; Aged; Cytarabine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Life Expectancy; Male; Middle Aged; Remission, Spontaneous; Thioguanine; Vincristine

1977
Paraparesis following intrathecal cytosine arabinoside: a case report with neuropathologic findings.
    Cancer, 1977, Volume: 40, Issue:6

    Topics: Aged; Cytarabine; Humans; Injections, Spinal; Leukemia, Myeloid, Acute; Male; Muscle Spasticity; Spinal Cord

1977
Treatment of refractory acute leukemia with high-dose chemotherapy.
    Cancer treatment reports, 1977, Volume: 61, Issue:7

    Topics: Adolescent; Adult; Antineoplastic Agents; Child; Cyclophosphamide; Cytarabine; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Semustine; Thioguanine

1977
Treatment of acute myeloid leukaemia with a triple cytotoxic regime: DAT.
    British journal of cancer, 1977, Volume: 36, Issue:6

    Topics: Adolescent; Adult; Aged; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Remission, Spontaneous; Thioguanine

1977
Treatment of acute non-lymphoid leukemias: comparison of two protocols.
    Osterreichische Zeitschrift fur Onkologie. Austrian journal of oncology, 1977, Dec-19, Volume: 4, Issue:4

    Topics: Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisone; Prognosis; Thioguanine; Vincristine

1977
[Results and problems in the treatment of childhood leukaemia (author's transl)].
    Monatsschrift fur Kinderheilkunde, 1978, Volume: 126, Issue:1

    Topics: Age Factors; Child; Cytarabine; Daunorubicin; Humans; Hungary; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Prednisolone; Thioguanine; Vincristine

1978
[Long term remission in acute myelogenous leukemia in adults].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1978, Jan-10, Volume: 98, Issue:1

    Topics: Adult; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Prednisone; Prognosis; Remission, Spontaneous; Vincristine

1978
Active immunotherapy in acute myelogenous leukaemia and the induction of second and subsequent remissions.
    British journal of cancer, 1978, Volume: 37, Issue:2

    Topics: BCG Vaccine; Cytarabine; Daunorubicin; Humans; Immunotherapy; Leukemia, Myeloid, Acute; Remission, Spontaneous; Time Factors

1978
Maintenance therapy of adult acute nonlymphoblastic leukemia: an argument against the need for central nervous system prophlyaxis.
    Cancer, 1978, Volume: 41, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission, Spontaneous; Thioguanine

1978
Treatment of acute leukaemia: implications of recent findings in cell biology.
    Folia biologica, 1978, Volume: 24, Issue:1

    Topics: Animals; Antiviral Agents; Asparaginase; Cell Cycle; Cytarabine; Hematopoietic Stem Cells; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute

1978
[Trysomy of chromosome 1 long arms plus chromosome 9 inversion in leukaemic cells (author's transl)].
    Sangre, 1978, Volume: 23, Issue:1

    Topics: Chromosome Aberrations; Chromosome Disorders; Cytarabine; Daunorubicin; Drug Resistance; Female; Humans; Karyotyping; Leukemia, Myeloid, Acute; Middle Aged; Trisomy

1978
[Delivery of a normal child after chemotherapy of acute promyelocytic leukaemia during pregnancy (author's transl)].
    Blut, 1978, Mar-15, Volume: 36, Issue:3

    Topics: Cesarean Section; Cytarabine; Daunorubicin; Female; Humans; Infant, Newborn; Infant, Premature; Leukemia, Myeloid, Acute; Pregnancy; Pregnancy Complications, Hematologic; Remission, Spontaneous

1978
Formation of 1-beta-D-arabinofuranosylcytosine diphosphate choline in cultured human leukemic RPMI 6410 cells.
    Cancer research, 1978, Volume: 38, Issue:6

    Topics: 3-Deazauridine; Animals; Cell Division; Cells, Cultured; Choline; Cytarabine; Cytidine Diphosphate Choline; Drug Synergism; Humans; Hydrolysis; Leukemia, Experimental; Leukemia, Myeloid, Acute

1978
Formation of 1-beta-D-arabinofuranosylcytosine diphosphate choline in neoplastic and normal cells.
    Cancer research, 1978, Volume: 38, Issue:6

    Topics: 3-Deazauridine; Animals; Choline; Cytarabine; Cytidine Diphosphate Choline; Drug Synergism; Female; HeLa Cells; Leukemia L1210; Leukemia, Experimental; Leukemia, Myeloid, Acute; Liver; Lymphocytes; Mice; Mice, Inbred Strains

1978
Effect of medium conditioned by acute myeloid leukaemia cells on normal marrow colony-forming ability and sensitivity to cytosine arabinoside.
    European journal of cancer, 1978, Volume: 14, Issue:6

    Topics: Bone Marrow; Bone Marrow Cells; Cell Survival; Clone Cells; Culture Media; Cytarabine; Humans; Leukemia, Myeloid, Acute

1978
[Selective treatment of leukemia L1210 with combination of deoxycytidine and lethal doses of cytosine arabinoside].
    Biulleten' eksperimental'noi biologii i meditsiny, 1978, Volume: 85, Issue:3

    Topics: Administration, Oral; Animals; Cytarabine; Deoxycytidine; Drug Evaluation; Drug Therapy, Combination; Injections, Intraperitoneal; Leukemia L1210; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mice

1978
[Progress in the treatment of acute leukemias].
    Schweizerische medizinische Wochenschrift, 1978, Aug-12, Volume: 108, Issue:32

    Topics: Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Prednisone; Remission, Spontaneous; Thioguanine; Vincristine

1978
Vincristine (NSC-67574), cytosine arabinoside (NSC-63878), 6 thioguanine (NSC-752) and daunorubicin (NSC-82151) (VAT-D): a pilot study of combination chemotherapy for remission induction in acute myeloid leukemia in adults.
    Medical and pediatric oncology, 1978, Volume: 4, Issue:3

    Topics: Adolescent; Adult; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Pilot Projects; Remission, Spontaneous; Thioguanine; Vincristine

1978
Therapy of acute myelogeneous leukemia.
    Cancer, 1978, Volume: 42, Issue:2 Suppl

    Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents; Cytarabine; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Fibrinogen; Humans; L-Lactate Dehydrogenase; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisone; Prognosis; Regression Analysis; Remission, Spontaneous; Time Factors; Vincristine

1978
Determination of cytosine arabinoside in human plasma by high-pressure liquid chromatography.
    Journal of chromatography, 1978, Sep-01, Volume: 146, Issue:2

    Topics: Chromatography, High Pressure Liquid; Cytarabine; Humans; Leukemia, Myeloid, Acute; Methods

1978
[Treatment of therapy-resistant acute non-lymphocytic leukemia with PADOC (author's transl)].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1978, Volume: 19, Issue:3

    Topics: Adult; Aged; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Resistance; Drug Therapy, Combination; Female; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisolone; Vincristine

1978
Razoxane in treatment of acute myeloid leukaemia.
    British medical journal, 1978, Oct-14, Volume: 2, Issue:6144

    Topics: Adolescent; Adult; Aged; Cytarabine; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Middle Aged; Piperazines; Razoxane; Remission, Spontaneous

1978
Razoxane in treatment of acute myeloid leukaemia.
    British medical journal, 1978, Oct-21, Volume: 2, Issue:6145

    Topics: Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Piperazines; Razoxane

1978
Remission induction in acute myelogenous leukemia using cytosine arabinoside synchronization: a Southwest Oncology Group Study.
    Medical and pediatric oncology, 1978, Volume: 4, Issue:4

    Topics: Adolescent; Bone Marrow; Cell Cycle; Child; Child, Preschool; Cytarabine; Drug Administration Schedule; Female; Humans; Infant; Infusions, Parenteral; Leukemia, Myeloid, Acute; Male; Remission, Spontaneous

1978
Paraplegia following intrathecal cytosine arabinoside.
    Cancer, 1979, Volume: 43, Issue:1

    Topics: Adult; Cytarabine; Humans; Injections, Spinal; Leukemia, Myeloid, Acute; Male; Paraplegia

1979
Correlation between leukemic cell retention of 1-beta-D-arabinofuranosylcytosine 5'-triphosphate and response to therapy.
    Cancer research, 1979, Volume: 39, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Bone Marrow; Cytarabine; Drug Therapy, Combination; Female; Humans; In Vitro Techniques; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission, Spontaneous; Time Factors

1979
[PADOC therapy of aged patients with acute non-lymphocytic leukemia (author's transl)].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1978, Volume: 19, Issue:10

    Topics: Aged; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisolone; Vincristine

1978
[Therapy of adult myeloblastic leukemia in complete remission with modified TRAP, COAP and POMP cycles].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1978, Issue:84

    Topics: Adult; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Prednisone; Thioguanine; Vincristine

1978
[Treatment of acute myeloblastic leukemia with cytosine arabinoside combined with daunorubicin or ifosfamide or thioguanine].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1978, Issue:84

    Topics: Adult; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Ifosfamide; Leukemia, Myeloid, Acute; Middle Aged; Thioguanine

1978
Multiple determinants of antimetabolite action in humans.
    Bulletin du cancer, 1979, Volume: 66, Issue:1

    Topics: Animals; Antimetabolites, Antineoplastic; Arabinofuranosylcytosine Triphosphate; Arabinofuranosyluracil; Cytarabine; Daunorubicin; Deamination; DNA; Doxorubicin; Drug Resistance; Humans; Leukemia, Myeloid, Acute; Neoplasms, Experimental

1979
The relevance of cell kinetics for optimal scheduling of 1-beta-D-arabinofuranosyl cytosine and methotrexate in a slow growing acute myeloid leukemia (BNML).
    Cancer chemotherapy and pharmacology, 1978, Volume: 1, Issue:4

    Topics: Animals; Bone Marrow Cells; Cell Division; Cytarabine; Drug Administration Schedule; Kinetics; Leukemia, Myeloid, Acute; Liver; Male; Methotrexate; Organ Size; Rats; Spleen; Time Factors

1978
The relationship of cytosine arabinoside phosphorylation to inhibition of DNA synthesis in human leukaemic myeloblasts [proceedings].
    British journal of clinical pharmacology, 1979, Volume: 7, Issue:4

    Topics: Cytarabine; DNA, Neoplasm; Humans; Leukemia, Myeloid, Acute; Phosphorylation

1979
Tn polyagglutination preceding acute leukemia.
    Blood, 1979, Volume: 54, Issue:1

    Topics: Aged; Cytarabine; Daunorubicin; Hemagglutination; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Splenectomy; Thioguanine; Thrombocytopenia

1979
Relevance of recruitment-synchronization in the scheduling of 1-beta-D-arabinofuranosylcytosine in a slow-growing acute myeloid leukemia of the rat.
    Cancer research, 1979, Volume: 39, Issue:7 Pt 1

    Topics: Animals; Cell Cycle; Colony-Forming Units Assay; Cytarabine; Hematopoietic Stem Cells; Interphase; Leukemia, Experimental; Leukemia, Myeloid, Acute; Male; Mice; Mice, Inbred Strains; Neoplasm Transplantation

1979
[Prognosis improvements in children with acute myelocytic leucemia after more intensive induction therapy (author's transl)].
    Klinische Padiatrie, 1979, Volume: 191, Issue:2

    Topics: Adolescent; Child; Child, Preschool; Cytarabine; Daunorubicin; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Prognosis; Thioguanine

1979
Pregancy complicated by acute myeloid leukaemia.
    The New Zealand medical journal, 1979, Mar-28, Volume: 89, Issue:632

    Topics: Adult; Blood Transfusion; Cytarabine; Drug Therapy, Combination; Female; Humans; Infant, Newborn; Leukemia, Myeloid, Acute; Platelet Transfusion; Pregnancy; Pregnancy Complications; Thioguanine

1979
Acute non-lymphocytic leukaemia in the third trimester of pregnancy.
    Australian and New Zealand journal of medicine, 1979, Volume: 9, Issue:1

    Topics: Adult; Cytarabine; Female; Humans; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Pregnancy; Pregnancy Complications; Pregnancy Trimester, Third; Thioguanine

1979
[Treatment of myeloblastic leukemia after 65 years. Results in 9 cases].
    La Nouvelle presse medicale, 1979, Mar-03, Volume: 8, Issue:10

    Topics: Aged; Antineoplastic Agents; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Remission, Spontaneous

1979
[Occurrence of infectious complications during therapy for acute leukemia].
    Vnitrni lekarstvi, 1979, Volume: 25, Issue:6

    Topics: Antineoplastic Agents; Bacterial Infections; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Neutropenia; Prednisone; Thioguanine

1979
Serial studies on in vitro colony formation in patients with acute leukemia in relation to the maintenance of remission.
    American journal of hematology, 1978, Volume: 5, Issue:4

    Topics: Acute Disease; Adult; Child; Colony-Forming Units Assay; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisolone; Remission, Spontaneous

1978
Mechanism of synergistic cell killing when methotrexate precedes cytosine arabinoside: study of L1210 and human leukemic cells.
    The Journal of clinical investigation, 1979, Volume: 64, Issue:3

    Topics: Animals; Arabinofuranosylcytosine Triphosphate; Cell Survival; Cells, Cultured; Cytarabine; Deoxyribonucleotides; Drug Synergism; Humans; In Vitro Techniques; Leukemia L1210; Leukemia, Myeloid, Acute; Methotrexate; Mice

1979
Acute myelogenous leukemia: morphologic classification and response to therapy.
    Leukemia research, 1979, Volume: 3, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Middle Aged; Platinum; Thioguanine

1979
Differentiation of myeloid leukaemic cells: new possibilities for therapy.
    British journal of haematology, 1979, Volume: 42, Issue:3

    Topics: Anemia, Aplastic; Cell Differentiation; Cytarabine; Humans; Leukemia, Myeloid, Acute; Leukocytes; Mitosis

1979
Improved survival in young children with acute granulocytic leukemia treated with combination therapy using cyclophosphamide, oncovin, cytosine arabinoside, and prednisone.
    Cancer, 1979, Volume: 44, Issue:3

    Topics: Adolescent; Age Factors; Antineoplastic Agents; Bone Marrow; Central Nervous System Diseases; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Prednisone; Remission, Spontaneous; Time Factors; Vincristine

1979
Pharmacokinetics of cytosine arabinoside in patients with acute myeloid leukaemia.
    British journal of clinical pharmacology, 1979, Volume: 8, Issue:3

    Topics: Adolescent; Adult; Aged; Cytarabine; Female; Half-Life; Humans; Kinetics; Leukemia, Myeloid, Acute; Male; Middle Aged; Time Factors

1979
Clinical and pharmacologic studies with adriamycin-DNA complex in children with malignant disease.
    Cancer chemotherapy and pharmacology, 1979, Volume: 2, Issue:1

    Topics: Child; Cytarabine; DNA; Doxorubicin; Evaluation Studies as Topic; Fibroblasts; Humans; Leukemia, Myeloid, Acute; Neoplasms

1979
Cytarabine and thioguanine for acute nonlymphocytic leukemia. Another look.
    Archives of internal medicine, 1979, Volume: 139, Issue:11

    Topics: Adolescent; Adult; Aged; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Platelet Count; Thioguanine

1979
[Treatment of acute myelogenous leukemia in children with a multiple-drug protocol (MINI-COAP regimen) (author's transl)].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1979, Volume: 20, Issue:9

    Topics: Adolescent; Antineoplastic Agents; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Prednisolone; Vincristine

1979
Cytarabine-induced inflammation in the seborrheic keratoses of Leser-Trélat.
    Annals of internal medicine, 1979, Volume: 91, Issue:6

    Topics: Aged; Cytarabine; Erythema; Female; Humans; Keratosis; Leukemia, Myeloid, Acute; Skin Manifestations

1979
Inhibition by arabinosylcytosine of DNA synthesis in bone marrows of relapsed AML patients.
    European journal of cancer, 1979, Volume: 15, Issue:10

    Topics: Adult; Aged; Bone Marrow; Cell Survival; Cytarabine; DNA, Neoplasm; Female; Humans; In Vitro Techniques; Leukemia, Myeloid, Acute; Male; Middle Aged; Thymidine

1979
The proliferative activity of leukaemic myeloblasts following the intravenous infusion of cytarabine.
    Pathology, 1979, Volume: 11, Issue:3

    Topics: Adolescent; Adult; Aged; Bone Marrow; Bone Marrow Cells; Cell Division; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitosis

1979
Effect of cytosine arabinoside on nuclear labelling of leukaemic myeloblasts with tritiated thymidine triphosphate.
    Leukemia research, 1979, Volume: 3, Issue:1

    Topics: Adult; Aged; Bone Marrow; Cell Nucleus; Cytarabine; Deoxycytosine Nucleotides; DNA Replication; DNA, Neoplasm; Female; Humans; Isotope Labeling; Kinetics; Leukemia, Myeloid, Acute; Male; Middle Aged; Thymidine; Thymine Nucleotides

1979
Treatment of adult acute myeloblastic leukemia.
    Haematology and blood transfusion, 1979, Volume: 23

    Topics: Adolescent; Adult; Aged; Cytarabine; Doxorubicin; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Middle Aged; Prednisone; Prognosis; Time Factors; Vincristine

1979
Prediction of therapeutic response in acute myelocytic leukemia.
    Haematology and blood transfusion, 1979, Volume: 23

    Topics: Arabinofuranosylcytosine Triphosphate; Benzimidazoles; Biological Transport; Cytarabine; DNA, Neoplasm; Doxorubicin; Drug Therapy, Combination; Fluorescence; Fluorescent Dyes; Humans; Leukemia, Myeloid, Acute; Phosphorylation

1979
Comparison of outcomes and prognostic factors for two groups of patients with acute myeloblastic leukemia.
    Leukemia research, 1979, Volume: 3, Issue:6

    Topics: Adult; Blood Cell Count; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Middle Aged; Prognosis; Quality of Life; Vincristine

1979
Meningeal involvement in leukemias and malignant lymphomas of adults: incidence, course of disease, and treatment for prevention.
    Acta neurologica Scandinavica, 1979, Volume: 60, Issue:6

    Topics: Adult; Cytarabine; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma; Meningeal Neoplasms; Methotrexate; Prognosis; Retrospective Studies; Time Factors

1979
Prognostic value of colony-stimulating and colony-forming cells in peripheral blood in acute non-lymphoblastic leukemia.
    Acta medica Scandinavica, 1977, Volume: 201, Issue:5

    Topics: Adult; Aged; Cell Division; Cells, Cultured; Clone Cells; Colony-Stimulating Factors; Cytarabine; Daunorubicin; Female; Humans; Leukemia; Leukemia, Myeloid, Acute; Leukocyte Count; Leukocytes; Male; Middle Aged; Prognosis; Remission, Spontaneous

1977
Effect of antileukaemic chemotherapy on helper and suppressor activity of T cells on immunoglobulin production by B cells.
    European journal of cancer, 1978, Volume: 14, Issue:9

    Topics: Aged; Antineoplastic Agents; B-Lymphocytes; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Immunoglobulin G; Immunosuppression Therapy; Leukemia, Myeloid, Acute; Lymphocyte Cooperation; Middle Aged; T-Lymphocytes; Thioguanine

1978
Intracerebral tumor and diffuse central nervous system infiltration complicating acute myelogenous leukemia.
    Cancer, 1979, Volume: 44, Issue:3

    Topics: Adult; Brain Neoplasms; Central Nervous System Diseases; Cytarabine; Female; Humans; Injections, Intraventricular; Leukemia, Myeloid, Acute; Meningeal Neoplasms; Tomography, Emission-Computed

1979
Deficiency of antibody-dependent cellular cytotoxicity and mitogen-induced cellular cytotoxicity effector cell function in patients with acute myelogenous leukemia in remission.
    Cancer research, 1979, Volume: 39, Issue:9

    Topics: Adult; Aged; Antibody-Dependent Cell Cytotoxicity; Antineoplastic Agents; Cytarabine; Cytotoxicity, Immunologic; Daunorubicin; Drug Therapy, Combination; Humans; Immunity, Cellular; Immunoglobulin Fc Fragments; Immunosuppression Therapy; Leukemia, Myeloid, Acute; Middle Aged; Phytohemagglutinins; Remission, Spontaneous; T-Lymphocytes; Thioguanine; Time Factors

1979
Colony-forming ability of marrow from patients receiving immunotherapy during chemotherapy-induced remission in acute myeloid leukaemia.
    Journal of clinical pathology, 1977, Volume: 30, Issue:1

    Topics: Adolescent; Adult; Aged; BCG Vaccine; Blood Cell Count; Bone Marrow; Bone Marrow Cells; Cell Division; Clone Cells; Cytarabine; Female; Granulocytes; Humans; Immunotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Mycobacterium bovis; Remission, Spontaneous

1977
Current treatment of acute leukemia.
    Comprehensive therapy, 1978, Volume: 4, Issue:2

    Topics: Bone Marrow Transplantation; Child; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Meningeal Neoplasms; Methotrexate; Neoplasm Metastasis; Prednisone; Vincristine

1978
[High dose combination chemotherapy with and without autologous bone marrow transplantation in patients with solid tumors and acute leukemias. Kinetics of recovery of peripheral bloods cells (author's transl)].
    La Nouvelle presse medicale, 1978, Volume: 7, Issue:45

    Topics: Adolescent; Adult; Antineoplastic Agents; Bone Marrow Transplantation; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Female; Hematopoiesis; Humans; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Lomustine; Male; Middle Aged; Neoplasms; Remission, Spontaneous; Thioguanine; Transplantation, Autologous

1978
Transurethral passage of Aspergillus fungus balls in acute myelocytic leukemia.
    Southern medical journal, 1979, Volume: 72, Issue:3

    Topics: Aspergillosis; Aspergillus fumigatus; Cytarabine; Daunorubicin; Humans; Immunosuppression Therapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Urethra; Urine

1979
Fatal veno-occlusive disease of the liver after chemotherapy, whole-body irradiation and bone marrow transplantation for refractory acute leukaemia.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1979, Jan-06, Volume: 55, Issue:1

    Topics: Adolescent; Bone Marrow Transplantation; Budd-Chiari Syndrome; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Liver; Lymph Nodes; Remission, Spontaneous; Transplantation, Homologous

1979
Acute promyelocytic leukemia: results of therapy and analysis of 13 cases.
    Acta haematologica, 1977, Volume: 58, Issue:2

    Topics: Adolescent; Adult; Aged; Blood Cell Count; Blood Platelets; Cytarabine; Daunorubicin; Doxorubicin; Female; Fibrinogen; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Remission, Spontaneous

1977
Granulocyte function in myeloblastic leukaemia.
    British journal of cancer, 1975, Volume: 32, Issue:5

    Topics: BCG Vaccine; Candida albicans; Cytarabine; Daunorubicin; Granulocytes; Humans; Hydrocortisone; Leukemia, Myeloid, Acute; Leukocytes; Mycobacterium bovis; Phagocytosis

1975
The effect of cytotoxic drugs on neutrophil phagocytosis in vitro and in patients with acute myelogenous leukaemia.
    British journal of haematology, 1976, Volume: 32, Issue:1

    Topics: Antineoplastic Agents; Candida albicans; Cell Survival; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Methotrexate; Neutrophils; Phagocytosis

1976
Perspectives and prospectives in the management of acute leukemia.
    Hamatologie und Bluttransfusion, 1976, Volume: 19

    Topics: BCG Vaccine; Cytarabine; Daunorubicin; Humans; Immunotherapy; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Life Expectancy; Mycobacterium bovis; Nucleotides, Cyclic; Prednisone; Remission, Spontaneous; Vincristine

1976
The management of acute myelogenous leukemia.
    The Medical clinics of North America, 1975, Volume: 59, Issue:2

    Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antineoplastic Agents; Blood Transfusion; Cell Division; Cyclophosphamide; Cytarabine; Drug Evaluation; Drug Synergism; Drug Therapy, Combination; Humans; Infection Control; Kinetics; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Mycoses; Prednisone; Pseudomonas Infections; Remission, Spontaneous; Thioguanine; Vincristine

1975
Pharmacological and clinical studies of some nucleoside analogs.
    Annals of the New York Academy of Sciences, 1975, Aug-08, Volume: 255

    Topics: Allopurinol; Cytarabine; Guanosine; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Nucleosides; Uridine

1975
[Hematologic intensive care units for cancer patients. Their role in the efficacy of cytostatic chemotherapy].
    La Nouvelle presse medicale, 1975, May-24, Volume: 4, Issue:21

    Topics: Antineoplastic Agents; Blood Transfusion; Bone Marrow Cells; Bone Marrow Transplantation; Cross Infection; Cytarabine; Daunorubicin; Hemorrhage; Humans; Immunosuppression Therapy; Infection Control; Intensive Care Units; Leukemia, Myeloid, Acute; Patient Isolators; Thioguanine

1975
Fibrinogen survival with 75-seleniomethionine in acute myeloblastic leukemia during polychemotherapy.
    Haematologica, 1976, Volume: 61, Issue:1

    Topics: Adult; Antibiotics, Antineoplastic; Cytarabine; Daunorubicin; Fibrinogen; Humans; Leukemia, Myeloid, Acute; Prednisolone; Selenomethionine

1976
epsilon-Amino-caproic acid in the management of acute promyelocytic leukaemia.
    Acta haematologica, 1976, Volume: 56, Issue:4

    Topics: Adult; Aminocaproates; Aminocaproic Acid; Cytarabine; Daunorubicin; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Vincristine

1976
[Use of pulse cytophotometry in hematology].
    Acta histochemica. Supplementband, 1976, Volume: 16

    Topics: Aneuploidy; Blood Cells; Bone Marrow; Cell Cycle; Cytarabine; Cytological Techniques; DNA, Neoplasm; Doxorubicin; Humans; Leukemia, Myeloid, Acute; Photometry

1976
Sequential therapy for induction and maintenance of remission in acute myeloblastic leukemia.
    Cancer, 1975, Volume: 35, Issue:2

    Topics: Adolescent; Adult; Age Factors; Antineoplastic Agents; Child; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Remission, Spontaneous; Time Factors; Vincristine

1975
Methoxy-9-ellipticine lactate in refractory acute myeloid leukaemia.
    Postgraduate medical journal, 1975, Volume: 51, Issue:592

    Topics: Administration, Oral; Adolescent; Alkaloids; Antineoplastic Agents; Carbazoles; Child; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Leukemia, Myeloid, Acute; Mercaptopurine; Methyl Ethers; Prednisone; Remission, Spontaneous; Time Factors

1975
De novo appearance of the ph-1 chromosome in a previously monosomic bone marrow (45,XX,-6): conversion of a myeloproliferative disorder to acute myelogenous leukemia.
    Blood, 1975, Volume: 45, Issue:5

    Topics: Adult; Alkaline Phosphatase; Blood Transfusion; Bone Marrow Cells; Bone Marrow Examination; Chromosome Aberrations; Chromosomes, Human, 21-22 and Y; Chromosomes, Human, 6-12 and X; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Female; Humans; Karyotyping; Leukemia, Myeloid, Acute; Leukocytes; Myeloproliferative Disorders; Prednisone; Vincristine

1975
Treatment of therapy-resistant acute myeloid leukaemia with 7 and 8 cytostatics.
    Scandinavian journal of haematology, 1975, Volume: 14, Issue:1

    Topics: Adolescent; Adult; Aged; Candidiasis; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Resistance; Drug Therapy, Combination; Esophagitis, Peptic; Female; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Leukocyte Count; Leukopenia; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisolone; Stomach Ulcer; Thioguanine; Vincristine

1975
Treatment of acute myelogenous leukaemia in adults. A retrospective study of 70 patients (1968-1973).
    The Netherlands journal of medicine, 1975, Volume: 18, Issue:1

    Topics: Adult; Antineoplastic Agents; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Retrospective Studies; Thioguanine

1975
[Treatment of acute myeloblastic leukemia. Experiences with "conventional" single-drug therapy, 1968-70, and intensive combination chemotherapy, 1971-73].
    Ugeskrift for laeger, 1975, Feb-17, Volume: 137, Issue:8

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisone; Vincristine

1975
Drugs five years later: cytarabine.
    Annals of internal medicine, 1975, Volume: 82, Issue:5

    Topics: Acute Disease; Adult; Animals; Bone Marrow Diseases; Central Nervous System Diseases; Cyclophosphamide; Cytarabine; Daunorubicin; DNA, Neoplasm; Drug Therapy, Combination; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma; Prednisone; Remission, Spontaneous; Thioguanine; Vincristine; Virus Diseases

1975
Acute leukemia in adults: assessment of remission induction with combination chemotherapy by clinical and cell-culture criteria.
    Canadian Medical Association journal, 1975, Aug-23, Volume: 113, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Aged; Bone Marrow; Bone Marrow Cells; Cell Division; Cells, Cultured; Clone Cells; Culture Media; Cyclophosphamide; Cytarabine; Drug Administration Schedule; Drug Therapy, Combination; Female; Granulocytes; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Remission, Spontaneous; Vincristine

1975
Cell kinetics and practical consequences for therapy of acute leukemia.
    The New England journal of medicine, 1975, Aug-21, Volume: 293, Issue:8

    Topics: Adrenal Cortex Hormones; Asparaginase; Bone Marrow; Bone Marrow Cells; Cell Division; Cells, Cultured; Cytarabine; Daunorubicin; DNA; DNA, Neoplasm; Drug Therapy, Combination; Humans; Kinetics; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate; Mitosis; Prognosis; Vincristine

1975
[Therapy of non-lymphoid acute leukemias].
    Minerva medica, 1975, Jul-14, Volume: 66, Issue:51

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Body Weight; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Middle Aged; Remission, Spontaneous; Thioguanine; Vincristine

1975
[Cytokinetics, chemotherapy and clinical course of acute leukemias].
    Minerva medica, 1975, Jul-14, Volume: 66, Issue:51

    Topics: Animals; Antineoplastic Agents; Cytarabine; Humans; Kinetics; Leukemia, Experimental; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mice; Mitosis; Prognosis

1975
[Evolution and therapy of blastic crises].
    Minerva medica, 1975, Jul-14, Volume: 66, Issue:51

    Topics: Bone Marrow; Cytarabine; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Spleen

1975
[Our recent therapeutic experiences in acute leukemia].
    Minerva medica, 1975, Jul-14, Volume: 66, Issue:51

    Topics: Adolescent; Adult; Antineoplastic Agents; Asparaginase; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Therapy, Combination; Evaluation Studies as Topic; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate; Middle Aged; Prednisone; Vincristine

1975
[Treatment of 17 cases of non-lymphoblastic acute leukemia with a combination of daunorubicin, cytosine and arabinoside].
    Minerva medica, 1975, Jul-28, Volume: 66, Issue:52

    Topics: Adolescent; Adult; Aged; Child; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged

1975
[General remarks on the treatment of acute leukemias].
    Minerva medica, 1975, Jul-28, Volume: 66, Issue:52

    Topics: Asparaginase; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Prednisone; Thioguanine; Vincristine

1975
Treatment of acute leukemia in adults.
    Cancer, 1975, Volume: 36, Issue:2

    Topics: Adolescent; Adult; Aged; Asparaginase; Carmustine; Child; Cytarabine; Daunorubicin; Female; Humans; Hydroxyurea; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Remission, Spontaneous; Thioguanine; Vincristine

1975
Fever in acute myelogenous leukemia.
    Archives of internal medicine, 1975, Volume: 135, Issue:9

    Topics: Agranulocytosis; Anti-Bacterial Agents; Candidiasis; Cytarabine; Daunorubicin; Fever; Humans; Klebsiella Infections; Leukemia, Myeloid, Acute; Pseudomonas Infections; Thioguanine

1975
Cyclocytidine study in the treatment of acute leukemia.
    Bibliotheca haematologica, 1975, Issue:40

    Topics: Cytarabine; Drug Evaluation; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Prednisolone

1975
[Clinical use of cytosine arabinoside in childhood. II. Cytosine arabinoside in the prevention and therapy of leukemic meningosis].
    Minerva pediatrica, 1975, Sep-29, Volume: 27, Issue:30

    Topics: Adolescent; Brain Neoplasms; Child; Child, Preschool; Cytarabine; Female; Humans; Infant; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Remission, Spontaneous

1975
[Letter: New combination drug therapy of acute myeloid leukemia].
    La Nouvelle presse medicale, 1975, Sep-13, Volume: 4, Issue:29

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoguazone; Remission, Spontaneous; Vincristine

1975
Letter: Cytarabine: therapeutic trials and editorial standards.
    Annals of internal medicine, 1975, Volume: 83, Issue:4

    Topics: Cytarabine; Drug Evaluation; Humans; Leukemia, Myeloid, Acute; Remission, Spontaneous

1975
Treatment of acute leukemia during pregnancy.
    Cancer, 1975, Volume: 36, Issue:3

    Topics: Adult; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Pregnancy; Pregnancy Complications, Hematologic; Pregnancy Trimester, Second; Thioguanine

1975
Hypoplastic acute myelogenous leukaemia.
    British journal of haematology, 1975, Volume: 31, Issue:2

    Topics: Adult; Aged; Cytarabine; Daunorubicin; Female; Humans; Immunotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission, Spontaneous

1975
A comparative study of acute myeloblastic leukaemia in children and adults.
    British journal of haematology, 1975, Volume: 31, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Blood Cell Count; Blood Platelets; Bone Marrow Cells; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Infant; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Prednisone; Remission, Spontaneous; Thioguanine; Vincristine

1975
Treatment of acute myeloid leukemia of childhood with cytosine arabinoside, daunorubicin, prednisolone, and mercaptopurine or thioguanine.
    Cancer, 1975, Volume: 36, Issue:5

    Topics: Antineoplastic Agents; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Prednisolone; Remission, Spontaneous; Thioguanine

1975
[Results of combined chemotherapy in treatment-resistant leukaemia of adults (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1975, Nov-28, Volume: 100, Issue:48

    Topics: Acute Disease; Adolescent; Adult; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia; Leukemia, Myeloid, Acute; Methotrexate; Middle Aged; Prednisone; Remission, Spontaneous; Thioguanine; Time Factors; Vincristine

1975
Cytokinetics of human acute leukemia before and after chemotherapy.
    European journal of cancer, 1975, Volume: 11, Issue:7

    Topics: Adolescent; Adult; Asparaginase; Bone Marrow; Bone Marrow Cells; Cell Division; Cells, Cultured; Child; Cytarabine; DNA, Neoplasm; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphocytes; Male; Thioguanine; Thymidine

1975
Daunorubicin, cytosine arabinoside, 6-mercaptopurine riboside, and prednisolone (DCMP) combination chemotherapy for acute myelogenous leukemia in adults.
    Cancer, 1975, Volume: 36, Issue:6

    Topics: Adolescent; Adult; Age Factors; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Inosine; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisolone; Remission, Spontaneous; Thioinosine

1975
Acute myeloid leukemia in the adult.
    Bulletin de la Societe des sciences medicales du Grand-Duche de Luxembourg, 1975, Volume: 112, Issue:2

    Topics: Adult; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Thioguanine

1975
Cell proliferation and protein synthesis in human leukaemic myeloblasts after cytosine arabinoside therapy.
    British journal of haematology, 1976, Volume: 32, Issue:2

    Topics: Adult; Bone Marrow; Bone Marrow Cells; Cytarabine; Depression, Chemical; Female; Humans; Injections, Intravenous; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitosis; Neoplasm Proteins; Time Factors

1976
[The therapy of acute myelogenous leukemia].
    Schweizerische medizinische Wochenschrift, 1975, Oct-04, Volume: 105, Issue:40

    Topics: Cyclophosphamide; Cytarabine; Daunorubicin; Drug Administration Schedule; Humans; Leukemia, Myeloid, Acute; Lomustine; Thioguanine

1975
[Pharmakokinetics of hydroxy-urea. Therapy of acute myeoblastic leukemias using synchronization and recruitment effects (author' transl)].
    Klinische Wochenschrift, 1976, Mar-01, Volume: 54, Issue:5

    Topics: Administration, Oral; Adult; Cell Division; Cytarabine; DNA, Neoplasm; Half-Life; Humans; Hydroxyurea; Kinetics; Leukemia, Myeloid, Acute; Middle Aged; Time Factors

1976
Manipulation of the mitotic cycle in the treatment of acute myelogenous leukaemia.
    British journal of haematology, 1976, Volume: 32, Issue:1

    Topics: Adolescent; Adult; Bone Marrow Examination; Child; Child, Preschool; Cytarabine; Daunorubicin; DNA; Doxorubicin; Female; Humans; Infant; Infant, Newborn; Infusions, Parenteral; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitosis; Remission, Spontaneous; Time Factors

1976
Effect of arabinosyl cytosine on granulopoietic colony formation by marrow cells from leukemic and non-leukemic patients.
    Experimental hematology, 1976, Volume: 4, Issue:2

    Topics: Bone Marrow; Bone Marrow Cells; Cell Division; Cell Survival; Clone Cells; Cytarabine; Cytidine Deaminase; Granulocytes; Hematopoiesis; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocytes; Remission, Spontaneous

1976
Nuclear DNA-polymerase estimation in human leukaemic myeloblasts.
    British journal of haematology, 1976, Volume: 33, Issue:3

    Topics: Bone Marrow; Bone Marrow Cells; Cell Nucleus; Cell Transformation, Neoplastic; Cytarabine; DNA Nucleotidyltransferases; Humans; In Vitro Techniques; Leukemia, Myeloid, Acute; Methotrexate; Neoplasm Proteins; Thymidine; Thymine Nucleotides; Tritium

1976
[A patient with anemia].
    Nederlands tijdschrift voor geneeskunde, 1976, Jul-10, Volume: 120, Issue:28

    Topics: Aged; Anemia; Blood Cell Count; Bone Marrow Examination; Cytarabine; Diagnosis, Differential; Female; Humans; Leukemia, Myeloid, Acute; Primary Myelofibrosis; Thioguanine

1976
[Experiences in the treatment of acute myeloblastic leukemia and acute monocytic leukemia using cytosine arabinoside and 6-thioguanine].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1975, Volume: 81

    Topics: Adult; Aged; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Thioguanine

1975
Serial quantitative observations of leukemic and normal hematopoietic cells in the bone marrow of acute leukemia under chemotherapy.
    The Tohoku journal of experimental medicine, 1976, Volume: 119, Issue:1

    Topics: Bone Marrow; Bone Marrow Cells; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Prednisolone; Remission, Spontaneous; Vincristine

1976
[Neonatal leukemia. Report of seven cases (author's transl)].
    Anales espanoles de pediatria, 1976, Volume: 9, Issue:4 Suppl

    Topics: Cytarabine; Daunorubicin; Humans; Infant, Newborn; Infant, Newborn, Diseases; Leukemia, Myeloid, Acute

1976
[Results in the treatment of acute leukemias at the Internal Clinic B in the period 1970-1975].
    Bilten za hematologiju i transfuziju, 1976, Volume: 4, Issue:1-2

    Topics: Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Hospitals, University; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Prednisone; Remission, Spontaneous; Vincristine

1976
Enhancement of drug cytotoxicity by recruitment of leukemic myeloblasts with humoral stimulation.
    Cancer research, 1976, Volume: 36, Issue:10

    Topics: Bone Marrow; Bone Marrow Cells; Cell Count; Cell Division; Cell Survival; Cells, Cultured; Cytarabine; Humans; Leukemia, Myeloid, Acute; Thymidine

1976
The metabolism of cytosine arabinoside as a predictive test for clinical response to the drug in acute myeloid leukaemia.
    European journal of cancer, 1976, Volume: 12, Issue:7

    Topics: Adult; Aged; Cells, Cultured; Cytarabine; Deamination; Female; Freezing; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Phosphates; Remission, Spontaneous

1976
Combinations of arabinosyl cytosine and 6-thioguanine for treatment of adults with acute leukemia.
    Medical and pediatric oncology, 1975, Volume: 1, Issue:1

    Topics: Adolescent; Adult; Aged; Bone Marrow; Cytarabine; DNA; Drug Therapy, Combination; Female; Hematopoietic Stem Cells; Humans; Injections, Intravenous; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission, Spontaneous; Thioguanine

1975
Treatment of adult acute non-lymphoblastic leukemia using intermittent combination chemotherapy with daunomycin, cytosine arabinoside, 6-mercaptopurine and prednisolone-DCMP two step therapy.
    The Tohoku journal of experimental medicine, 1976, Volume: 118 Suppl

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisolone; Remission, Spontaneous

1976
Endomyocardial fibrosis associated with daunorubicin therapy.
    British heart journal, 1976, Volume: 38, Issue:8

    Topics: Adult; Cytarabine; Daunorubicin; Endomyocardial Fibrosis; Female; Humans; Leukemia, Myeloid, Acute

1976
A mathematical model of the chemotherapeutic treatment of acute myeloblastic leukemia.
    Biophysical journal, 1976, Volume: 16, Issue:11

    Topics: Cytarabine; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Mathematics; Models, Biological; Thioguanine

1976
Veno-occlusive disease of the liver after chemotherapy of acute leukemia. Report of two cases.
    Annals of internal medicine, 1976, Volume: 85, Issue:5

    Topics: Acute Disease; Adolescent; Aged; Budd-Chiari Syndrome; Chemical and Drug Induced Liver Injury; Cytarabine; Hepatic Veins; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Liver; Male; Thioguanine

1976
Chemoimmunotherapy for maintenance in acute myeloblastic leukemia.
    Cancer, 1976, Volume: 38, Issue:4

    Topics: Adolescent; Adult; Aged; Antigens, Neoplasm; BCG Vaccine; Cytarabine; Daunorubicin; Female; Humans; Immunotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission, Spontaneous; Thioguanine; Time Factors

1976
Sequencing of cytosine arabinoside (NSC-63878) and daunorubicin (NSC-82151) in acute myelogenous leukemia.
    Cancer treatment reports, 1976, Volume: 60, Issue:5

    Topics: Adolescent; Adult; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

1976
A sensitive bio-assay for pharmacokinetic studies of cytosine arabinoside in man.
    European journal of cancer, 1976, Volume: 12, Issue:11

    Topics: Animals; Biological Assay; Bone Marrow; Bone Marrow Cells; Cytarabine; DNA; Half-Life; Humans; In Vitro Techniques; Leukemia, Myeloid, Acute; Rats; Thymidine; Time Factors

1976
Acute granulocytic leukemia: treatment of the disease.
    Archives of internal medicine, 1976, Volume: 136, Issue:12

    Topics: Adolescent; Adult; Age Factors; Blood Transfusion; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Immunotherapy; Infant; Leukemia, Myeloid, Acute; Lomustine; Meningitis; Middle Aged; Prognosis; Thioguanine

1976
[The treatment of acute myelocytic leukemia during the first recurrence by means of a new cytostatic combination].
    Schweizerische medizinische Wochenschrift, 1976, Sep-18, Volume: 106, Issue:38

    Topics: Cytarabine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Etoposide; Humans; Leukemia, Myeloid, Acute; Podophyllotoxin; Thioguanine; Vincristine

1976
Comparative observations in the treatment of acute leukaemia.
    Haematologia, 1976, Volume: 10, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Child; Cytarabine; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Middle Aged; Prednisolone; Remission, Spontaneous; Thioguanine; Vincristine

1976
[Treatment of acute leukemia in adults by the OAP regimen].
    Klinicheskaia meditsina, 1976, Volume: 54, Issue:8

    Topics: Adult; Cytarabine; Drug Evaluation; Drug Therapy, Combination; Humans; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Prednisolone; Remission, Spontaneous; Time Factors; Vincristine

1976
Vinblastine, procarbazine, and cytosine arabinoside in combination for reinduction of childhood acute myelocytic leukemia.
    Cancer treatment reports, 1976, Volume: 60, Issue:11

    Topics: Child; Child, Preschool; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Procarbazine; Vinblastine

1976
Short induction treatment in acute granulocytic leukemia.
    Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1975, Sep-10, Volume: 23, Issue:7

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Fever; Hemorrhage; Humans; Leucovorin; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Pyruvaldehyde; Remission, Spontaneous; Sepsis

1975
Sequential use of methotrexate, folinic acid, and cytosine arabinoside in the treatment of acute leukemia.
    European journal of cancer, 1976, Volume: 12, Issue:8

    Topics: Adult; Bone Marrow; Bone Marrow Cells; Child; Cytarabine; Deoxyuridine; DNA; Drug Administration Schedule; Female; Humans; In Vitro Techniques; Leucovorin; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Mitosis; Thymidine; Thymine

1976
Cytomegalovirus infection in children with blood diseases.
    Acta haematologica Polonica, 1992, Volume: 23, Issue:3

    Topics: Adolescent; Anemia, Aplastic; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Cytomegalovirus Infections; Daunorubicin; Female; gamma-Globulins; Humans; Immune Tolerance; Immunization, Passive; Infant; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Methotrexate; Opportunistic Infections; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Thioguanine; Vincristine

1992
Usefulness of bone-marrow biopsy during induction therapy for acute myeloid leukemia.
    Lancet (London, England), 1992, Jan-18, Volume: 339, Issue:8786

    Topics: Biopsy, Needle; Bone Marrow Examination; Cytarabine; Daunorubicin; Evaluation Studies as Topic; Humans; Leukemia, Myeloid, Acute; Remission Induction; Retrospective Studies; Time Factors

1992
Overexpression of multidrug resistance-associated p170-glycoprotein in acute non-lymphocytic leukemia.
    European journal of haematology, 1992, Volume: 48, Issue:2

    Topics: Adolescent; Adult; Aged; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Marrow; Cytarabine; Daunorubicin; Drug Resistance; Gene Expression; Humans; Leukemia, Myeloid, Acute; Membrane Glycoproteins; Middle Aged; Mitoxantrone; Neoplasm Recurrence, Local; Remission Induction

1992
A discrepancy between the instantaneous and the overall collection efficiency of the Fenwal CS3000 for peripheral blood stem cell apheresis.
    Journal of clinical apheresis, 1992, Volume: 7, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Blood Cells; Blood Component Removal; Blood Transfusion, Autologous; Bone Marrow Diseases; Cyclophosphamide; Cytarabine; Daunorubicin; Evaluation Studies as Topic; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Neoplasms; Thioguanine

1992
Multidrug resistance (MDR) gene expression in acute non lymphoblastic leukemia: sequential analysis.
    Leukemia & lymphoma, 1992, Volume: 8, Issue:4-5

    Topics: Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Gene Expression Regulation, Leukemic; Humans; Leukemia, Myeloid, Acute; Male; Membrane Glycoproteins; Middle Aged; Mitoxantrone; Neoplasm Proteins; Remission Induction

1992
ABEP as primary chemotherapy for Hodgkin's disease.
    European journal of cancer (Oxford, England : 1990), 1992, Volume: 28A, Issue:10

    Topics: Aclarubicin; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cytarabine; Doxorubicin; Etoposide; Female; Follow-Up Studies; Hodgkin Disease; Humans; Leukemia, Myeloid, Acute; Male; Mechlorethamine; Middle Aged; Myelodysplastic Syndromes; Neoplasms, Second Primary; Prednisolone; Prednisone; Procarbazine; Vincristine

1992
[Countermeasure for treatment of leukemia in the aged].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1992, Jul-10, Volume: 81, Issue:7

    Topics: Aged; Chromosome Aberrations; Creatinine; Cytarabine; Drug Therapy, Combination; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Middle Aged; Vincristine

1992
A predictive model for the clinical response to low dose ara-C: a study of 102 patients with myelodysplastic syndromes or acute leukaemia.
    British journal of haematology, 1992, Volume: 81, Issue:4

    Topics: Aged; Aged, 80 and over; Anemia, Sideroblastic; Bone Marrow; Chromosome Aberrations; Cytarabine; Female; Humans; Karyotyping; Leukemia, Myeloid, Acute; Male; Myelodysplastic Syndromes; Platelet Count; Predictive Value of Tests

1992
[Treatment of various types of acute leukemia in adult. An analysis of 98 cases. The Leukemia Cooperation Group of Beijing City].
    Zhonghua nei ke za zhi, 1992, Volume: 31, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Vincristine

1992
[A regimen of DATV in the treatment of acute nonlymphocytic leukemia with high complete remission rate].
    Zhonghua nei ke za zhi, 1992, Volume: 31, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prospective Studies; Remission Induction; Thioguanine; Vincristine

1992
Progress and survival factors in acute non lymphocytic leukemia. A 15 year analysis.
    Nouvelle revue francaise d'hematologie, 1992, Volume: 34, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Middle Aged; Prognosis; Survival Rate

1992
Comparison of the proliferative activity and sensitivity to cytosine arabinoside of leukemic blast progenitors in acute myeloblastic leukemia at diagnosis and in relapse.
    Acta haematologica, 1992, Volume: 88, Issue:1

    Topics: Blast Crisis; Cell Division; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid, Acute; Neoplastic Stem Cells; Recurrence; Tumor Cells, Cultured

1992
Acute myelogenous leukemia: proliferation stop or cell lysis during the first hours of treatment?
    American journal of hematology, 1992, Volume: 41, Issue:3

    Topics: Cell Death; Cell Division; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Time Factors

1992
Increase in the D-dimer levels during treatment in patients with acute myelogenous leukemia.
    Haemostasis, 1992, Volume: 22, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Antithrombin III; Child; Cytarabine; Daunorubicin; Disseminated Intravascular Coagulation; Female; Fibrin Fibrinogen Degradation Products; Fibrinolysis; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Peptide Hydrolases; Plasminogen Activator Inhibitor 2; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator

1992
["Small doses" of cytosar in the therapy of acute nonlymphoblastic leukemias].
    Terapevticheskii arkhiv, 1992, Volume: 64, Issue:7

    Topics: Adult; Aged; Cytarabine; Dose-Response Relationship, Drug; Drug Evaluation; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Remission Induction; Time Factors

1992
Survival in 91 adults with acute myelogenous leukaemia treated with 1-6 intensive courses of chemotherapy.
    Journal of internal medicine, 1992, Volume: 232, Issue:5

    Topics: Actuarial Analysis; Adolescent; Adult; Age Factors; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Examination; Bone Marrow Transplantation; Cause of Death; Combined Modality Therapy; Cytarabine; Daunorubicin; Etoposide; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Leukocyte Count; Middle Aged; Norway; Recurrence; Remission Induction; Survival Analysis; Survival Rate; Thioguanine

1992
[Cure of acute myeloblastic leukemia in a child with Down syndrome and tetralogy of Fallot].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1992, Volume: 45, Issue:5-6

    Topics: Abnormalities, Multiple; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Down Syndrome; Humans; Infant; Leukemia, Myeloid, Acute; Male; Remission Induction; Tetralogy of Fallot; Thioguanine

1992
Cell cycle-specific metabolism of arabinosyl nucleosides in K562 human leukemia cells.
    Cancer chemotherapy and pharmacology, 1992, Volume: 31, Issue:1

    Topics: Antineoplastic Agents; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cell Cycle; Cytarabine; Deoxycytidine Kinase; Drug Synergism; G1 Phase; G2 Phase; Humans; Intracellular Fluid; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Metaphase; Nucleotides; S Phase; Sensitivity and Specificity; Tumor Cells, Cultured; Vidarabine

1992
Fulminant hepatic failure after high-dose cytosine arabinoside and mitoxantrone treatment for relapse of acute myelogenous leukaemia.
    European journal of haematology, 1992, Volume: 49, Issue:4

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Liver; Liver Failure, Acute; Mitoxantrone; Necrosis; Recurrence; Thioguanine

1992
Recurrent neutrophilic eccrine hidradenitis.
    The British journal of dermatology, 1992, Volume: 127, Issue:5

    Topics: Adult; Cytarabine; Eccrine Glands; Female; Hidradenitis; Humans; Injections, Intravenous; Leukemia, Myeloid, Acute; Methylprednisolone; Mitoxantrone; Recurrence; Skin

1992
Efficacy of low-dose cytarabine therapy in myelodysplastic syndromes.
    The Journal of the Association of Physicians of India, 1992, Volume: 40, Issue:7

    Topics: Aged; Bone Marrow Examination; Cytarabine; Drug Administration Schedule; Female; Humans; Injections, Subcutaneous; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Prospective Studies; Treatment Failure

1992
Effects of bryostatin 1 and rGM-CSF on the metabolism of 1-beta-D-arabinofuranosylcytosine in human leukaemic myeloblasts.
    British journal of haematology, 1992, Volume: 82, Issue:3

    Topics: Antineoplastic Agents; Arabinofuranosylcytosine Triphosphate; Bryostatins; Cytarabine; Drug Interactions; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Lactones; Leukemia, Myeloid, Acute; Macrolides; Recombinant Proteins; Time Factors

1992
Low-dose combination remission induction therapy for acute myeloid leukaemia in elderly patients--a pilot study.
    Australian and New Zealand journal of medicine, 1992, Volume: 22, Issue:6

    Topics: Aged; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Pilot Projects; Remission Induction

1992
Jaundice following high--dose arabinoside cytosine in a child with acute myelogenous leukemia.
    Acta haematologica Polonica, 1992, Volume: 23, Issue:3

    Topics: Administration, Oral; Cytarabine; Drug Administration Schedule; Female; Humans; Hyperbilirubinemia; Infant; Jaundice; Leukemia, Myeloid, Acute; Remission Induction; Remission, Spontaneous; Time Factors

1992
[Evaluation of 58 patients with acute leukemia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction; Retrospective Studies; Survival Rate; Treatment Outcome

1992
[Intensive induction chemotherapy of adult acute myelogenous leukemia by continuing daunorubicin, behenoyl-cytosine arabinoside, 6-mercaptopurine and prednisolone until marrow aplasia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:9

    Topics: Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Injections, Intravenous; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisolone; Remission Induction; Sepsis; Survival Rate

1992
[High dose cinobufocini in attenuation and treatment of infection and granulocytopenia during combined chemotherapy of malignant blood diseases].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1992, Volume: 12, Issue:3

    Topics: Adolescent; Adult; Aged; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Bufanolides; Cyclophosphamide; Cytarabine; Female; Humans; Infection Control; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Vincristine

1992
Serial changes of the serum macrophage colony-stimulating factor level after cytoreductive chemotherapy.
    International journal of hematology, 1992, Volume: 55, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Enzyme-Linked Immunosorbent Assay; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Leukocyte Count; Leukopenia; Macrophage Colony-Stimulating Factor; Male; Mercaptopurine; Middle Aged; Mitoxantrone; Predictive Value of Tests; Prednisone; Remission Induction; Vindesine

1992
Clustering of adverse drug events: analysis of risk factors for cerebellar toxicity with high-dose cytarabine.
    Journal of the National Cancer Institute, 1992, Apr-01, Volume: 84, Issue:7

    Topics: Adolescent; Adult; Aged; Cerebellar Diseases; Cerebellum; Cohort Studies; Creatinine; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Risk Factors

1992
Eccrine squamous syringometaplasia in chemotherapy-induced acral erythema.
    Journal of the American Academy of Dermatology, 1992, Volume: 26, Issue:2 Pt 1

    Topics: Cytarabine; Eccrine Glands; Epithelium; Erythema; Foot Dermatoses; Hand Dermatoses; Humans; Leukemia, Myeloid, Acute; Metaplasia

1992
Leukemic cell death during heating is well fitted with the Gompertz-Makeham's formula--a law of human mortality.
    Experimental hematology, 1992, Volume: 20, Issue:3

    Topics: Bone Marrow Transplantation; Cell Death; Cytarabine; Dose-Response Relationship, Drug; Hot Temperature; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid, Acute; Mathematics; Regression Analysis; Tumor Cells, Cultured

1992
Treatment of newly diagnosed acute myelogenous leukemia with granulocyte-macrophage colony-stimulating factor (GM-CSF) before and during continuous-infusion high-dose ara-C + daunorubicin: comparison to patients treated without GM-CSF.
    Blood, 1992, May-01, Volume: 79, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Survival Rate

1992
Pulmonary complications of acute myelogenous leukemia.
    New Jersey medicine : the journal of the Medical Society of New Jersey, 1992, Volume: 89, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Diagnosis, Differential; Humans; Leukemia, Myeloid, Acute; Lung Neoplasms; Male; Middle Aged; Mitoxantrone; Tomography, X-Ray Computed

1992
Corneal and conjunctival toxicity with low-dose cytosine arabinoside.
    American journal of ophthalmology, 1992, May-15, Volume: 113, Issue:5

    Topics: Conjunctiva; Cornea; Cytarabine; Dexamethasone; Humans; Keratoconjunctivitis; Leukemia, Myeloid, Acute; Male; Middle Aged; Visual Acuity

1992
[Second marrow transplantation following high dose busulfan, etoposide, and Ara-C after testicular relapse in a patient with AML].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1992, Volume: 33, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Combined Modality Therapy; Cytarabine; Etoposide; Humans; Leukemia, Myeloid, Acute; Male; Remission Induction; Testicular Neoplasms

1992
High-dose cytosine arabinoside intensification for acute nonlymphocytic leukemia in patients over 56 years of age.
    Annals of hematology, 1992, Volume: 64, Issue:4

    Topics: Aged; Aged, 80 and over; Cytarabine; Dose-Response Relationship, Drug; Drug Tolerance; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Thrombocytopenia

1992
Low-dose cytosine arabinoside as an alternative treatment for acute leukemia in Jehovah's Witnesses.
    American journal of hematology, 1992, Volume: 40, Issue:2

    Topics: Adolescent; Adult; Christianity; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged

1992
Leukemia following cisplatin-based chemotherapy for ovarian carcinoma at Roswell Park.
    European journal of gynaecological oncology, 1992, Volume: 13, Issue:2

    Topics: Adult; Carcinoma, Papillary; Cisplatin; Cyclophosphamide; Cytarabine; Doxorubicin; Female; Humans; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Middle Aged; Neoplasms, Second Primary; Ovarian Neoplasms; Thrombocytopenia

1992
Expression of glutathione transferase pi as a predictor for treatment results at different stages of acute nonlymphoblastic leukemia.
    Cancer research, 1992, Jun-15, Volume: 52, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Glutathione Transferase; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Recurrence; Remission Induction; Thioguanine; Time Factors

1992
Phenotypic analysis of 1-B-D-arabinofuranosylcytosine deamination in patients treated with high doses and correlation with response.
    Cancer chemotherapy and pharmacology, 1992, Volume: 30, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arabinofuranosyluracil; Cytarabine; Deamination; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Phenotype; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Serum Albumin, Bovine; Sex Factors

1992
Predicting remission outcome in acute non-lymphocytic leukemia: general principles and their application to residual marrow leukemia.
    Leukemia research, 1992, Volume: 16, Issue:5

    Topics: Bone Marrow; Bone Marrow Examination; Cytarabine; Humans; Leukemia, Myeloid, Acute; Likelihood Functions; Predictive Value of Tests; Prognosis; Recurrence; Remission Induction

1992
Comparison of the effects of all-trans and cis-retinoic acid on the blast stem cells of acute myeloblastic leukemia in culture.
    Leukemia, 1992, Volume: 6, Issue:7

    Topics: Cell Survival; Cytarabine; Drug Administration Schedule; In Vitro Techniques; Leukemia, Myeloid, Acute; Neoplastic Stem Cells; Stereoisomerism; Tretinoin; Tumor Cells, Cultured

1992
Cost of complete remission induction in acute myeloblastic leukemia: evaluation of the cost-effectiveness of a new drug.
    Leukemia, 1992, Volume: 6, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Costs and Cost Analysis; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Mitoxantrone

1992
[Short-term intensive consolidation chemotherapy in the treatment of acute non-lymphocytic leukemia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Prednisolone; Remission Induction; Survival Rate

1992
The in vitro growth patterns and drug sensitivities of leukemic blast progenitors among the subtypes of acute myelocytic leukemia.
    Experimental hematology, 1992, Volume: 20, Issue:7

    Topics: Adolescent; Adult; Aged; Blast Crisis; Cell Division; Cytarabine; Humans; Leukemia, Myeloid, Acute; Remission Induction; Stem Cells

1992
Electrical alternans of the T-U wave without change in the QRS complex.
    Internal medicine (Tokyo, Japan), 1992, Volume: 31, Issue:4

    Topics: Aclarubicin; Antineoplastic Combined Chemotherapy Protocols; Arrhythmias, Cardiac; Cytarabine; Daunorubicin; Electrocardiography; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged

1992
Multiparameter assessment of the cell cycle effects of bioactive and cytotoxic agents.
    Cancer research, 1992, Aug-01, Volume: 52, Issue:15

    Topics: Animals; Bone Marrow; Bromodeoxyuridine; Cell Cycle; Cell Nucleus; Cell Survival; Cells, Cultured; Chickens; Cytarabine; DNA Replication; DNA, Neoplasm; G1 Phase; G2 Phase; Interferon alpha-2; Interferon-alpha; Kinetics; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Mitosis; Propidium; Recombinant Proteins; S Phase; Tretinoin; Tumor Cells, Cultured

1992
Therapy of acute myelogenous leukemia: results of combination chemotherapy with cytarabine, daunorubicin and 6-mercaptopurine.
    Zhonghua yi xue za zhi = Chinese medical journal; Free China ed, 1991, Volume: 48, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Evaluation; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Remission Induction

1991
Fatal peripheral neuropathy associated with axonal degeneration after high-dose cytosine arabinoside in acute leukaemia.
    British journal of haematology, 1991, Volume: 79, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Axons; Cytarabine; Humans; Leukemia, Myeloid, Acute; Male; Peripheral Nervous System Diseases; Sural Nerve

1991
Double intensification with amsacrine/high dose ara-C and high dose chemotherapy with autologous bone marrow transplantation produces durable remissions in acute myelogenous leukemia.
    Bone marrow transplantation, 1990, Volume: 5, Issue:2

    Topics: Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow Transplantation; Cisplatin; Combined Modality Therapy; Cytarabine; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Survival Rate; Vindesine

1990
High dose ARA-C as induction therapy of acute myeloid leukaemia.
    Folia haematologica (Leipzig, Germany : 1928), 1990, Volume: 117, Issue:1

    Topics: Adult; Cytarabine; Dose-Response Relationship, Drug; Female; Hematopoiesis; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Time Factors

1990
Cytosine arabinoside (ara-C) and cis-dichlorodiammineplatinum II (cisplatin) alone and in combination: effects on acute myeloblastic leukemia blast cells in culture and in vivo.
    Leukemia, 1991, Volume: 5, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cytarabine; Drug Evaluation; Drug Screening Assays, Antitumor; Drug Synergism; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Middle Aged; Recombinant Proteins; Tumor Cells, Cultured

1991
OCI/AML-4 an acute myeloblastic leukemia cell line: regulation and response to cytosine arabinoside.
    Leukemia, 1991, Volume: 5, Issue:8

    Topics: Antigens, CD; Blotting, Northern; Cell Division; Cell Survival; Cytarabine; Gene Expression; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Cell Growth Factors; Humans; Hydrocortisone; In Vitro Techniques; Interleukin-3; Interleukin-6; Leukemia, Myeloid, Acute; Macrophage Colony-Stimulating Factor; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-kit; Receptor, Macrophage Colony-Stimulating Factor; Stem Cell Factor; Tretinoin; Tumor Cells, Cultured

1991
Granulocyte-macrophage colony-stimulating factor and interleukin-3 protect leukemic blast cells from ara-C toxicity.
    Leukemia, 1991, Volume: 5, Issue:9

    Topics: Adult; Aged; Cell Survival; Cytarabine; DNA, Neoplasm; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-3; Leukemia, Myeloid, Acute; Middle Aged; Recombinant Proteins; Thymidine; Tumor Cells, Cultured

1991
Bone marrow transplantation versus high-dose cytarabine-based consolidation chemotherapy for acute myelogenous leukemia in first remission.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1992, Volume: 10, Issue:1

    Topics: Actuarial Analysis; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Survival Analysis; Transplantation, Homologous

1992
Novel translocation (2;4) with consistent involvement of 2p23 in acute nonlymphocytic leukemia (M2).
    Cancer genetics and cytogenetics, 1992, Volume: 58, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 2; Chromosomes, Human, Pair 4; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Remission Induction; Translocation, Genetic

1992
Laboratory determination of chemotherapeutic drug resistance in tumor cells from patients with leukemia, using a fluorometric microculture cytotoxicity assay (FMCA).
    International journal of cancer, 1992, Jan-21, Volume: 50, Issue:2

    Topics: Antineoplastic Agents; Cytarabine; Doxorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Fluorometry; Humans; Leukemia, Experimental; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Tumor Cells, Cultured

1992
Modulation of the cellular pharmacokinetics of ara-CTP in human leukemic blasts by dipyridamole.
    Cancer chemotherapy and pharmacology, 1992, Volume: 29, Issue:3

    Topics: Biological Transport; Cytarabine; Dipyridamole; Drug Interactions; Humans; Leukemia, Myeloid, Acute; Models, Biological; Tumor Cells, Cultured

1992
Epirubicin and cytosine arabinoside for the induction therapy of childhood acute nonlymphocytic leukemia.
    American journal of hematology, 1991, Volume: 38, Issue:4

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Epirubicin; Humans; Leukemia, Myeloid, Acute; Remission Induction

1991
The treatment of patients with newly diagnosed poor prognosis acute myelogenous leukaemia: response to treatment and treatment failure.
    British journal of haematology, 1991, Volume: 79, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Resistance; Humans; Leukemia, Myeloid, Acute; Middle Aged; Pilot Projects; Prognosis; Remission Induction; Time Factors

1991
Use of plasma cytotoxic activity to model cytotoxic pharmacodynamics of anticancer drugs.
    Cancer chemotherapy and pharmacology, 1991, Volume: 29, Issue:2

    Topics: Adult; Aged; Cytarabine; Daunorubicin; Deoxycytidine; Female; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Tumor Cells, Cultured

1991
Cell kinetics with in vivo bromodeoxyuridine and flow cytometry: clinical significance in acute non-lymphoblastic leukaemia.
    European journal of cancer (Oxford, England : 1990), 1991, Volume: 27, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bromodeoxyuridine; Cells; Cytarabine; Daunorubicin; Female; Flow Cytometry; Humans; Infusions, Intravenous; Kinetics; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Prospective Studies; Vincristine

1991
Incidence and clinical epidemiology of streptococcal septicemia during treatment of acute myeloid leukemia.
    Scandinavian journal of infectious diseases, 1991, Volume: 23, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Humans; Incidence; Leukemia, Myeloid, Acute; Middle Aged; Prognosis; Recurrence; Remission Induction; Retrospective Studies; Sepsis; Streptococcal Infections

1991
[Intensification chemotherapy followed by allogenieic and autologous bone marrow transplantation in acute non-lymphoblastic leukemia in children].
    Sangre, 1991, Volume: 36, Issue:1

    Topics: Adolescent; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Daunorubicin; Etoposide; Evaluation Studies as Topic; Female; Humans; Infant; Leukemia, Myeloid, Acute; Life Tables; Male; Methotrexate; Mitoxantrone; Remission Induction; Survival Rate; Thioguanine; Transplantation, Autologous; Transplantation, Homologous

1991
Interleukin-1 beta expression and treatment outcome in acute myelogenous leukemia.
    Blood, 1991, Aug-01, Volume: 78, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Blotting, Northern; Bone Marrow; Cytarabine; Daunorubicin; Gene Expression; Humans; Interleukin-1; Leukemia, Myeloid, Acute; Prognosis; Remission Induction; Transcription, Genetic

1991
Hydrocortisone in culture protects the blast cells in acute myeloblastic leukemia from the lethal effects of cytosine arabinoside.
    Journal of cellular physiology, 1991, Volume: 148, Issue:1

    Topics: Blast Crisis; Cell Survival; Cytarabine; DNA; Dose-Response Relationship, Drug; Doxorubicin; Humans; Hydrocortisone; Leukemia, Myeloid, Acute; Thymidine; Time Factors; Tritium; Tumor Cells, Cultured

1991
Plasma and cerebrospinal fluid pharmacokinetics of 1-beta-D-arabinofuranosylcytosine and 1-beta-D-arabinofuranosyluracil following the repeated intravenous administration of high- and intermediate-dose 1-beta-D-arabinofuranosylcytosine.
    Cancer research, 1991, Aug-15, Volume: 51, Issue:16

    Topics: Adult; Arabinofuranosyluracil; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Regression Analysis

1991
Treatment of cytarabine acral erythema with corticosteroids.
    Journal of the American Academy of Dermatology, 1991, Volume: 24, Issue:6 Pt 1

    Topics: Adult; Cytarabine; Erythema; Facial Dermatoses; Foot Dermatoses; Hand Dermatoses; Hodgkin Disease; Humans; Leukemia, Myeloid, Acute; Male; Prednisone

1991
Amsacrine is safe and effective therapy for patients with myocardial dysfunction and acute leukemia.
    Cancer, 1991, Sep-15, Volume: 68, Issue:6

    Topics: Amsacrine; Cardiac Output, Low; Cytarabine; Drug Therapy, Combination; Humans; Leukemia; Leukemia, Myeloid, Acute; Myocardium; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Stroke Volume

1991
[Combination treatment of acute non-lymphocytic leukemia with HOAP and AA--preliminary report of 14 cases].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1991, Volume: 13, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Doxorubicin; Female; Harringtonines; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisone; Vincristine

1991
Differential effect of interleukin 3 on the metabolism of high-dose cytosine arabinoside in normal versus leukemic human bone marrow cells.
    Experimental hematology, 1991, Volume: 19, Issue:7

    Topics: Bone Marrow; Cytarabine; Deoxycytosine Nucleotides; DNA; Humans; Interleukin-3; Leukemia, Myeloid, Acute; Recombinant Proteins

1991
Alterations in oral microflora and pathogenesis of acute oral infections during remission-induction therapy in patients with acute myeloid leukaemia.
    Scandinavian journal of infectious diseases, 1991, Volume: 23, Issue:3

    Topics: Aclarubicin; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bacteria, Aerobic; Bacteria, Anaerobic; Bacterial Infections; Candidiasis; Cytarabine; Enterobacteriaceae; Enterococcus faecalis; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mouth; Mouth Diseases; Prospective Studies; Remission Induction; Saliva

1991
Therapy of advanced acute myeloblastic leukemia with cytarabine and interleukin 2.
    Leukemia research, 1991, Volume: 15, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transplantation; Child, Preschool; Combined Modality Therapy; Cytarabine; Female; Humans; Interferon-gamma; Interleukin-2; Leukemia, Myeloid, Acute; Male; Neutrophils

1991
[Gastroenterologic findings in graft versus host disease after allogenic bone marrow transplantation].
    Zeitschrift fur Gastroenterologie, 1991, Volume: 29, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Etoposide; Female; Gastrointestinal Diseases; Graft vs Host Disease; Humans; Infant, Newborn; Intestinal Mucosa; Leukemia, Myeloid, Acute; Liver; Pregnancy; Pregnancy Complications, Neoplastic; Sigmoidoscopy

1991
Recurrent bilateral parotitis in acute myeloid leukemia.
    Acta haematologica, 1991, Volume: 86, Issue:1

    Topics: Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Parotitis; Recurrence

1991
Bone marrow transplant retinopathy.
    American journal of ophthalmology, 1991, Dec-15, Volume: 112, Issue:6

    Topics: Adolescent; Adult; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Dose-Response Relationship, Radiation; Female; Follow-Up Studies; Humans; Incidence; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radiotherapy; Retinal Diseases; Visual Acuity

1991
Granulocyte-macrophage colony-stimulating factor in acute non-lymphocytic leukemia before and after chemotherapy.
    Annals of hematology, 1991, Volume: 63, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Etoposide; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Remission Induction; Time Factors

1991
Anti-CD33 monoclonal antibody and etoposide/cytosine arabinoside combinations for the ex vivo purification of bone marrow in acute nonlymphocytic leukemia.
    Blood, 1991, Jan-15, Volume: 77, Issue:2

    Topics: Antibodies, Monoclonal; Antibody-Dependent Cell Cytotoxicity; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Cell Separation; Cell Survival; Colony-Forming Units Assay; Combined Modality Therapy; Cytarabine; Drug Administration Schedule; Etoposide; Humans; Immunotherapy; In Vitro Techniques; Leukemia, Myeloid, Acute; Sialic Acid Binding Ig-like Lectin 3; Tumor Stem Cell Assay

1991
High-dose cytosine arabinoside and etoposide in the treatment of relapsed or refractory adult leukemia.
    American journal of clinical oncology, 1991, Volume: 14, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Remission Induction; Survival Rate

1991
High-dose cytarabine and daunorubicin induction and postremission chemotherapy for the treatment of acute myelogenous leukemia in adults.
    Blood, 1991, Apr-01, Volume: 77, Issue:7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Prognosis; Remission Induction

1991
In vitro chemosensitivity of newly diagnosed and relapsing acute non-lymphoid leukemia patients.
    Tumori, 1991, Feb-28, Volume: 77, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Resistance; Drug Screening Assays, Antitumor; Female; Humans; Idoxuridine; Iodine Radioisotopes; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Tumor Cells, Cultured

1991
Intensive sequential chemotherapy with mitoxantrone and continuous infusion etoposide and cytarabine for previously treated acute myelogenous leukemia.
    Blood, 1991, May-01, Volume: 77, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Etoposide; Humans; L-Lactate Dehydrogenase; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Neoplasm Recurrence, Local; Remission Induction

1991
[Successful pregnancy after 6 years complete remission in patient with acute myeloblastic leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1991, Volume: 32, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Prednisolone; Pregnancy; Remission Induction

1991
Tissue factor released from leukemic cells.
    Thrombosis and haemostasis, 1991, Jan-23, Volume: 65, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Blood Coagulation; Cytarabine; Daunorubicin; Disseminated Intravascular Coagulation; Endotoxins; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Prednisolone; Thromboplastin; Tumor Cells, Cultured

1991
[Clinical effects of low-dose Ara-C in acute nonlymphocytic leukemia and myelodysplastic syndromes].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1991, Volume: 32, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Remission Induction; Survival Rate

1991
First and second complete remissions in a HIV positive patient following remission induction therapy for acute non-lymphoblastic leukaemia.
    Australian and New Zealand journal of medicine, 1991, Volume: 21, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Etoposide; HIV Seropositivity; Humans; Karyotyping; Leukemia, Myeloid, Acute; Male; Remission Induction; Substance Abuse, Intravenous

1991
Mitoxantrone, etoposide, and intermediate-dose cytarabine: an effective and tolerable regimen for the treatment of refractory acute myeloid leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1991, Volume: 9, Issue:7

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Drug Administration Schedule; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Survival Rate

1991
Coincidence of acquired factor-X deficiency and disseminated intravascular coagulation in patients with acute nonlymphoblastic leukemia.
    Annals of hematology, 1991, Volume: 62, Issue:5

    Topics: Adult; Aged; Cytarabine; Daunorubicin; Disseminated Intravascular Coagulation; Factor X; Factor X Deficiency; Female; Fibrinogen; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

1991
Necrotizing fasciitis of previous surgical wound complicating intensive postremission chemotherapy.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 1991, Volume: 74, Issue:2

    Topics: Adolescent; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Appendicitis; Cytarabine; Doxorubicin; Escherichia coli Infections; Fasciitis; Humans; Leukemia, Myeloid, Acute; Male; Surgical Wound Infection

1991
High-dose cytarabine for intensification of early therapy of childhood acute myeloid leukemia: a Pediatric Oncology Group study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1991, Volume: 9, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Humans; Infant; Leukemia, Myeloid, Acute; Pilot Projects; Prognosis; Recurrence; Remission Induction; Survival Rate

1991
Aspergillus appendicitis in acute myeloid leukaemia.
    Clinical and laboratory haematology, 1990, Volume: 12, Issue:4

    Topics: Adult; Amphotericin B; Antineoplastic Combined Chemotherapy Protocols; Appendicitis; Appendix; Aspergillosis; Combined Modality Therapy; Cytarabine; Daunorubicin; Humans; Ileal Diseases; Iliac Vein; Intestinal Perforation; Ischemia; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Neutropenia; Thrombosis

1990
Drug sensitivity test for acute myeloblastic leukemia by an efficient leukemic blast colony assay using 5637-conditioned medium as a stimulator.
    Journal of medicine, 1990, Volume: 21, Issue:6

    Topics: Aclarubicin; Adult; Aged; Aged, 80 and over; Culture Media; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Tumor Stem Cell Assay

1990
Comparative effects of busulfan, cytosine arabinoside and adriamycin on different maturation stages of normal human bone marrow cells.
    Acta haematologica, 1990, Volume: 83, Issue:1

    Topics: Bone Marrow; Bone Marrow Cells; Busulfan; Cell Differentiation; Cell Division; Cell Survival; Cells, Cultured; Colony-Forming Units Assay; Cytarabine; Dose-Response Relationship, Drug; Doxorubicin; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Tumor Cells, Cultured

1990
Etoposide in remission induction of adult acute myeloid leukemia.
    Acta haematologica, 1990, Volume: 83, Issue:2

    Topics: Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Evaluation; Etoposide; Humans; Leukemia, Myeloid, Acute; Remission Induction; Retrospective Studies; Thioguanine; Time Factors

1990
The effects of leukemia inhibitory factor (LIF) on the blast stem cells of acute myeloblastic leukemia.
    Leukemia, 1990, Volume: 4, Issue:8

    Topics: Cell Cycle; Cytarabine; Growth Inhibitors; Humans; Interleukin-6; Leukemia Inhibitory Factor; Leukemia, Myeloid, Acute; Lymphokines; Neoplastic Stem Cells; Recombinant Proteins; Thymidine; Time Factors; Tumor Cells, Cultured; Tumor Stem Cell Assay

1990
Erythema and swelling of ears after treatment with cytarabine for leukemia.
    European journal of cancer (Oxford, England : 1990), 1990, Volume: 26, Issue:5

    Topics: Cytarabine; Ear Diseases; Erythema; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

1990
[Aplastic anemia which terminated in hypoplastic leukemia 10 years after diagnosis].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1990, Volume: 31, Issue:9

    Topics: Anemia, Aplastic; Bone Marrow; Cholecalciferol; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Middle Aged

1990
Remission induction of ANLL with low dose cytosine arabinoside combined with retinoic acid.
    Zhonghua yi xue za zhi = Chinese medical journal; Free China ed, 1990, Volume: 46, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etretinate; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction

1990
How to improve therapy for adult acute myeloid leukemia: studies of the AML Cooperative Group in the Federal Republic of Germany.
    Journal of cancer research and clinical oncology, 1990, Volume: 116, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colony-Stimulating Factors; Cytarabine; Daunorubicin; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Humans; Leukemia, Myeloid, Acute; Middle Aged; Survival Rate; Thioguanine

1990
Management of febrile episodes during neutropenia caused by chemotherapy.
    American journal of clinical oncology, 1990, Volume: 13, Issue:2

    Topics: Adult; Agranulocytosis; Cytarabine; Fever; Humans; Klebsiella Infections; Klebsiella pneumoniae; Leukemia, Myeloid, Acute; Male; Neutropenia

1990
Treatment of poor-prognosis, newly diagnosed acute myelogenous leukemia with high-dose cytosine arabinoside (Ara-C) and rHUGM-CSF.
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Aged; Colony-Stimulating Factors; Combined Modality Therapy; Cytarabine; Drug Synergism; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Humans; Leukemia, Myeloid, Acute; Middle Aged; Prognosis; Recombinant Proteins; Remission Induction

1990
Treatment of poor-prognosis, newly diagnosed acute myeloid leukemia with ara-C and recombinant human granulocyte-macrophage colony-stimulating factor.
    Blood, 1990, May-01, Volume: 75, Issue:9

    Topics: Adult; Aged; Colony-Stimulating Factors; Cytarabine; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Humans; Leukemia, Myeloid, Acute; Middle Aged; Prognosis; Recombinant Proteins

1990
Cumulative bone marrow stromal damage caused by X-irradiation and cytosine-arabinoside in leukemic mice.
    Medical oncology and tumor pharmacotherapy, 1990, Volume: 7, Issue:1

    Topics: Animals; Bone Marrow; Cells, Cultured; Cytarabine; Leukemia, Myeloid, Acute; Male; Mice; Mice, Inbred C57BL; Whole-Body Irradiation

1990
Immunologic and morphologic typing as prognostic factor in M1 acute myeloblastic leukemia.
    Journal of chemotherapy (Florence, Italy), 1990, Volume: 2, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Child; Cytarabine; Daunorubicin; Female; Histocytochemistry; Humans; Immunoenzyme Techniques; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Vincristine

1990
Effects of rhGM-CSF on intracellular ara-C pharmacology in vitro in acute myelocytic leukemia: comparability with drug-induced humoral stimulatory activity.
    Leukemia, 1990, Volume: 4, Issue:8

    Topics: Adult; Aged; Biotransformation; Bone Marrow; Cell Division; Colony-Stimulating Factors; Cytarabine; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Humans; Leukemia, Myeloid, Acute; Middle Aged; Recombinant Proteins; Tumor Cells, Cultured

1990
Induction chemotherapy for newly diagnosed acute myeloid leukaemia using a regime containing cytosine arabinoside, daunorubicin and etoposide.
    Cancer chemotherapy and pharmacology, 1990, Volume: 26, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Chi-Square Distribution; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Survival Rate

1990
[Studies on intracellular kinetics of ara-C triphosphate in HL-60, human leukemia cells in relation to reasonable administration of ara-C].
    Nihon Gan Chiryo Gakkai shi, 1990, Jul-20, Volume: 25, Issue:7

    Topics: Arabinofuranosylcytosine Triphosphate; Biological Transport, Active; Biotransformation; Cytarabine; Humans; Leukemia, Myeloid, Acute; Tumor Cells, Cultured

1990
Different sensitivity of normal and leukaemic progenitor cells to Ara-C and IL-3 combined treatment.
    British journal of haematology, 1990, Volume: 76, Issue:1

    Topics: Cell Division; Cytarabine; Drug Synergism; Growth Substances; Hematopoietic Stem Cells; Humans; In Vitro Techniques; Interleukin-3; Leukemia, Myeloid, Acute; Neoplastic Stem Cells; Recombinant Proteins; Tumor Cells, Cultured

1990
Idarubicin plus attenuated high-dose cytosine arabinoside in the treatment of relapsed and refractory acute leukemia.
    European journal of haematology, 1990, Volume: 45, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Neoplasm Recurrence, Local

1990
GM-CSF incubation prior to treatment with cytarabine or doxorubicin enhances drug activity against AML cells in vitro: a model for leukemia chemotherapy.
    Leukemia research, 1990, Volume: 14, Issue:9

    Topics: Cytarabine; DNA, Neoplasm; Doxorubicin; Drug Synergism; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Tumor Cells, Cultured

1990
Concordant changes of pyrimidine metabolism in blasts of two cases of acute myeloid leukemia after repeated treatment with ara-C in vivo.
    Leukemia, 1990, Volume: 4, Issue:11

    Topics: Adolescent; Adult; Arabinofuranosylcytosine Triphosphate; Cytarabine; DCMP Deaminase; Deoxycytidine Kinase; Deoxycytosine Nucleotides; Drug Resistance; Female; Humans; Leukemia, Myeloid, Acute; Male; Pyrimidines; Thymine Nucleotides

1990
Interstitial pneumonia and alpha-hemolytic Streptococcus sepsis in a child with malignancy who recently received cytosine arabinoside.
    The Pediatric infectious disease journal, 1990, Volume: 9, Issue:8

    Topics: Adolescent; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Pulmonary Fibrosis; Streptococcal Infections

1990
Kinetic rationale for cytokine-induced recruitment of myeloblastic leukemia followed by cycle-specific chemotherapy in vitro.
    Leukemia, 1990, Volume: 4, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Cell Survival; Cytarabine; Cytokines; Flow Cytometry; Humans; Leukemia, Myeloid, Acute; Recombinant Proteins; Tumor Cells, Cultured

1990
A complex chromosomal rearrangement and congenital anomalies in the progeny of a mother treated for childhood leukemia.
    Cancer genetics and cytogenetics, 1990, Nov-01, Volume: 50, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 12; Cytarabine; Humans; Infant, Newborn; Leukemia, Myeloid, Acute; Male; Prednisone; Vincristine

1990
Effects of N4-behenoyl-1-beta-D-arabinofuranosylcytosine on blast progenitors of acute myeloblastic leukemia.
    Cancer research, 1990, Dec-01, Volume: 50, Issue:23

    Topics: Adult; Aged; Antineoplastic Agents; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Cytarabine; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Leukemia, Myeloid, Acute; Middle Aged

1990
Flow cytometry DNA measurement for prediction of effect of therapy in acute leukemia.
    Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, 1990, Volume: 10, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; DNA, Neoplasm; Flow Cytometry; Humans; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis

1990
Direct relationship between remission duration in acute myeloid leukemia and cell cycle kinetics: a leukemia intergroup study.
    Blood, 1990, Dec-01, Volume: 76, Issue:11

    Topics: Bone Marrow; Bromodeoxyuridine; Cell Cycle; Cytarabine; Daunorubicin; Female; Humans; Kinetics; Leukemia, Myeloid, Acute; Male; S Phase

1990
[Low dose continuous infusion therapy with etoposide (VP-16) and cytosine arabinoside (Ara-C) for a patient with refractory acute myelogenous leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1990, Volume: 31, Issue:11

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Remission Induction

1990
Mitoxantrone and intermediate-dose cytarabine in relapsed or refractory acute myeloblastic leukemia.
    Nouvelle revue francaise d'hematologie, 1990, Volume: 32, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Prognosis; Recurrence; Remission Induction

1990
Septicemia due to Streptococcus mitis in neutropenic patients with acute leukemia.
    Blut, 1990, Volume: 61, Issue:6

    Topics: Adult; Cytarabine; Disseminated Intravascular Coagulation; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neutropenia; Penicillin G; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Quinolines; Respiratory Distress Syndrome; Sepsis; Streptococcal Infections

1990
Allogeneic bone marrow transplantation in a program of intensive sequential chemotherapy for children and young adults with acute nonlymphocytic leukemia in first remission.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1990, Volume: 8, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Doxorubicin; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Methotrexate; Neoplasm Recurrence, Local; Prednisolone; Probability; Remission Induction; Vincristine

1990
Cell kinetics after high dose cytosine arabinoside in patients with acute myelocytic leukemia.
    Blut, 1990, Volume: 60, Issue:2

    Topics: Adult; Aged; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Time Factors

1990
Cellular ara-CTP pharmacokinetics, response, and karyotype in newly diagnosed acute myelogenous leukemia.
    Leukemia, 1990, Volume: 4, Issue:2

    Topics: Amsacrine; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Chromosome Deletion; Chromosome Inversion; Cytarabine; Drug Resistance; Humans; Karyotyping; Leukemia, Myeloid, Acute

1990
Triple combination of retinoic acid, low concentration of cytarabine and dimethylformamide induces differentiation of human acute myeloid leukaemic blasts.
    Chemotherapy, 1990, Volume: 36, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Transformation, Neoplastic; Cytarabine; Dimethylformamide; Humans; Leukemia, Myeloid, Acute; Tretinoin

1990
Selective eradication of leukemic (L-CFU) versus normal (CFU-GM) myeloid progenitors in suspension culture utilizing a prolonged exposure to 1-B-D arabinofuranosylcytosine (Ara-C) and deoxycytidine (dCyd).
    Progress in clinical and biological research, 1990, Volume: 333

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Separation; Cells, Cultured; Cytarabine; Deoxycytidine; Granulocytes; Humans; Leukemia, Myeloid, Acute; Macrophages; Neoplastic Stem Cells; Stem Cells; Tumor Cells, Cultured

1990
Cytosine arabinoside does not cause differentiation in vitro of CFU-GM in marrow from normal, myelodysplastic or ANLL subjects.
    Leukemia research, 1990, Volume: 14, Issue:2

    Topics: Alkaline Phosphatase; Bone Marrow; Bone Marrow Cells; Cell Differentiation; Cytarabine; Granulocytes; Histocytochemistry; HLA-DR Antigens; Humans; Immunohistochemistry; In Vitro Techniques; Leukemia, Myeloid, Acute; Macrophages; Myelodysplastic Syndromes; Stem Cells

1990
Definition of refractoriness against conventional chemotherapy in acute myeloid leukemia: a proposal based on the results of retreatment by thioguanine, cytosine arabinoside, and daunorubicin (TAD 9) in 150 patients with relapse after standardized first l
    Leukemia, 1990, Volume: 4, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Resistance; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Survival Rate; Thioguanine

1990
Continuous intravenous administration of daunorubicin and cytarabine for remission induction of poor risk acute myelogenous leukaemias and myelodysplastic syndromes.
    The Netherlands journal of medicine, 1990, Volume: 36, Issue:1-2

    Topics: Acute Disease; Adult; Aged; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Middle Aged; Myelodysplastic Syndromes; Recurrence; Remission Induction; Time Factors

1990
Mitoxantrone, etoposide and cytarabine in the treatment of acute nonlymphocytic leukemia.
    Oncology, 1990, Volume: 47, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone

1990
Successful chemotherapy for acute myeloid leucaemia in HIV-infected patients.
    European journal of haematology, 1990, Volume: 44, Issue:2

    Topics: CD4 Antigens; Cytarabine; HIV Antibodies; HIV Infections; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Zidovudine

1990
Cellular pharmacokinetics of daunomycin in human leukemic blasts in vitro and in vivo.
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Neoplastic Stem Cells; Thioguanine; Tumor Cells, Cultured

1990
Double intensive consolidation chemotherapy (ICC) for acute myeloid leukemia.
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmustine; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Etoposide; France; Humans; Leukemia, Myeloid, Acute; Life Tables; Middle Aged; Neutropenia; Survival Rate

1990
Acute nonlymphocytic leukemia in adults: results obtained with TAD remission induction therapy.
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Drug Evaluation; Humans; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Life Tables; Middle Aged; Netherlands; Remission Induction; Survival Rate; Thioguanine

1990
Continuous infusion of mitoxantrone combined with high-dose cytarabine in refractory/relapsed acute myeloblastic leukemia and blast crisis of chronic myelogenous leukemia.
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Adolescent; Adult; Aged; Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; Austria; Blast Crisis; Cytarabine; Drug Evaluation; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma

1990
Treatment of recurrent acute myelogenous leukaemia at a single centre over a 10-year period.
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Adolescent; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Doxorubicin; Drug Evaluation; Humans; Interferon Type I; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Thioguanine; United Kingdom

1990
Treatment of advanced myelodysplastic syndromes: trend toward more aggressive chemotherapy?
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Evaluation; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Preleukemia; Remission Induction; Thioguanine

1990
Effect of antifungal therapy on hematological recovery after intensive antileukemic chemotherapy.
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Agranulocytosis; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Depression, Chemical; Hematopoiesis; Humans; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Life Tables; Mitoxantrone; Mycoses; Thioguanine; Thrombocytopenia

1990
High-dose chemotherapy with noncryopreserved autologous bone marrow transplantation for acute myeloid leukemia in first complete remission.
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Drug Evaluation; Etoposide; Humans; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Transplantation, Autologous

1990
[Clinical effect and pharmacokinetics of intermediate dose Ara-C therapy in a patient with acute non-lymphocytic leukemia with two CNS recurrences].
    Nihon Gan Chiryo Gakkai shi, 1990, Jan-20, Volume: 25, Issue:1

    Topics: Cytarabine; Humans; Leukemia, Myeloid, Acute; Male; Meningeal Neoplasms; Middle Aged

1990
Serum immunoreactive erythropoietin in children with acute leukaemia at various stages of disease--and the effects of treatment.
    European journal of haematology, 1990, Volume: 44, Issue:3

    Topics: Adolescent; Anemia; Child; Child, Preschool; Cytarabine; Dose-Response Relationship, Drug; Erythropoietin; Female; Hemoglobins; Humans; Infant; Leukemia, Myeloid, Acute; Longitudinal Studies; Lymphoma, Non-Hodgkin; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma

1990
Chemotherapy for acute non-lymphocytic leukemia with low-dose cytosine arabinoside (Ara-C).
    Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society, 1990, Volume: 53, Issue:1

    Topics: Adult; Aged; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

1990
Intensive therapy in elderly patients with acute myeloid leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1990, Volume: 8, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Remission Induction

1990
[Acute myeloid leukemia with poor prognosis: treatment with oral 4-demethoxydaunorubicin (idarubicin) and low-dose cytarabine via subcutaneous route].
    Schweizerische medizinische Wochenschrift, 1990, Apr-14, Volume: 120, Issue:15

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Female; Humans; Idarubicin; Injections, Subcutaneous; Leukemia, Myeloid, Acute; Male; Middle Aged

1990
High-dose cytosine arabinoside and L-asparaginase therapy for poor-risk adult acute nonlymphocytic leukemia. A retrospective study.
    Cancer, 1990, Jun-15, Volume: 65, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cytarabine; Female; Humans; Infusions, Intravenous; Injections, Intramuscular; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Remission Induction; Retrospective Studies; Survival Rate

1990
Prognostic value of dysmyelopoietic features in de novo acute myeloid leukaemia: a report on 132 patients.
    Clinical and laboratory haematology, 1990, Volume: 12, Issue:1

    Topics: Adolescent; Adult; Amsacrine; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chromosome Banding; Cytarabine; Daunorubicin; Female; Hemoglobins; Humans; Karyotyping; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Myelodysplastic Syndromes; Platelet Count; Prognosis; Remission Induction; Survival Rate

1990
High-dose cytosine arabinoside and mitoxantrone in previously-treated acute leukemia patients.
    European journal of haematology, 1990, Volume: 44, Issue:4

    Topics: Adolescent; Adult; Aged; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Infusions, Intravenous; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma

1990
Chemotherapy of adult acute myeloid leukaemia.
    Annals of the Academy of Medicine, Singapore, 1990, Volume: 19, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Thioguanine

1990
BAVC regimen and autologous bone marrow transplantation in patients with acute myelogenous leukemia in second remission.
    Blood, 1990, Jun-15, Volume: 75, Issue:12

    Topics: Adolescent; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmustine; Combined Modality Therapy; Cytarabine; Etoposide; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Middle Aged; Survival Analysis

1990
Acute non-lymphoblastic leukemia in children: prognostic factors and results of chemotherapy.
    Indian pediatrics, 1990, Volume: 27, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Prognosis; Remission Induction

1990
Cytogenetics are a predictive factor of response to low dose Ara-C in acute myelogenous leukemia (AML) in the elderly.
    Leukemia, 1990, Volume: 4, Issue:4

    Topics: Aged; Cytarabine; Female; Gene Rearrangement; Humans; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged

1990
Reversal of drug-resistance by cyclosporin-A in a patient with acute myelocytic leukaemia.
    British journal of haematology, 1990, Volume: 75, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclosporins; Cytarabine; Daunorubicin; Drug Resistance; Humans; Leukemia, Myeloid, Acute; Male; Tumor Cells, Cultured

1990
Intermediate-dose cytosine arabinoside and amsacrine. An effective regimen with low toxicity in refractory acute nonlymphocytic leukemia.
    Cancer, 1990, May-01, Volume: 65, Issue:9

    Topics: Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction

1990
High-dose chemotherapy and autologous bone marrow transplantation in acute myeloid leukemia.
    Blood, 1990, Aug-01, Volume: 76, Issue:3

    Topics: Adolescent; Adult; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Hematopoiesis; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Transplantation, Autologous; Transplantation, Homologous

1990
Clinical, biochemical and cytokinetic parameters for distinguishing smouldering and rapidly proliferating variants of acute leukaemia.
    European journal of haematology, 1990, Volume: 45, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anemia, Refractory, with Excess of Blasts; Bone Marrow; Cytarabine; DNA; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Retrospective Studies; Thymidine Kinase

1990
Intensive antileukemic treatment of patients younger than 65 years with myelodysplastic syndromes and secondary acute myelogenous leukemia.
    Cancer, 1990, Sep-01, Volume: 66, Issue:5

    Topics: Adult; Age Factors; Amsacrine; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Leukemia, Myeloid, Acute; Middle Aged; Myelodysplastic Syndromes; Prognosis; Remission Induction; Retrospective Studies

1990
Correlation of the proliferative index of residual leukemia with outcome in patients treated with sequential high dose ara-C and asparaginase.
    Leukemia, 1990, Volume: 4, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow; Cell Division; Cytarabine; DNA, Neoplasm; Drug Administration Schedule; Female; Flow Cytometry; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Remission Induction

1990
Schedule-dependent interaction of cytarabine plus doxorubicin or cytarabine plus mitoxantrone in acute myelocytic leukemia cells in culture.
    Leukemia, 1990, Volume: 4, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Survival; Cytarabine; Doxorubicin; Drug Administration Schedule; Drug Synergism; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Tumor Cells, Cultured; Tumor Stem Cell Assay

1990
[Individualized chemotherapy of adult acute nonlymphocytic leukemia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:8 Pt 1

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Evaluation; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisolone; Remission Induction

1990
[Analysis of the therapeutic efficacy and prognostic factors of intensive chemotherapy in 91 patients with acute nonlymphoblastic leukemia].
    Zhonghua nei ke za zhi, 1990, Volume: 29, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Doxorubicin; Female; Harringtonines; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Survival Rate; Thioguanine

1990
[Therapeutic results in acute myelogenous leukemia in the years from 1970 to 1982].
    Folia haematologica (Leipzig, Germany : 1928), 1985, Volume: 112, Issue:5

    Topics: Adolescent; Adult; Blood Transfusion; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Platelet Transfusion; Prednisone; Retrospective Studies; Thioguanine; Vincristine

1985
Treatment of disseminated intravascular coagulation in acute promyelocytic leukemia with low molecular weight heparinoid Org 10172.
    Cancer, 1986, Aug-01, Volume: 58, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chondroitin Sulfates; Cytarabine; Daunorubicin; Dermatan Sulfate; Disseminated Intravascular Coagulation; Drug Evaluation; Glycosaminoglycans; Heparinoids; Heparitin Sulfate; Humans; Leukemia, Myeloid, Acute; Middle Aged; Thioguanine; Time Factors

1986
Interaction of deoxycytidine and deoxycytidine analogs in normal and leukemic human myeloid progenitor cells.
    Leukemia research, 1986, Volume: 10, Issue:9

    Topics: Azacitidine; Cell Division; Cell Line; Colony-Forming Units Assay; Cytarabine; Decitabine; Deoxycytidine; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute

1986
Sensitivity to 5-azacytidine of blast progenitors in acute myeloblastic leukemia.
    Blood, 1987, Volume: 69, Issue:2

    Topics: Azacitidine; Cell Survival; Cells, Cultured; Cytarabine; Doxorubicin; Humans; Leukemia, Myeloid, Acute; Neoplastic Stem Cells; Tumor Stem Cell Assay

1987
Treatment of adults with acute myelogenous leukemia: prospective evaluation of high-dose cytarabine in consolidation chemotherapy and with bone marrow transplantation.
    Seminars in oncology, 1987, Volume: 14, Issue:2 Suppl 1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid, Acute; Middle Aged; Prognosis; Whole-Body Irradiation

1987
In vitro biochemical tests to evaluate the response to therapy of acute leukemia with cytosine arabinoside or 5-AZA-2'-deoxycytidine.
    Seminars in oncology, 1987, Volume: 14, Issue:2 Suppl 1

    Topics: Adult; Azacitidine; Cells, Cultured; Child; Cytarabine; Cytidine Deaminase; Decitabine; Deoxycytidine Kinase; DNA Replication; DNA, Neoplasm; Drug Resistance; Humans; In Vitro Techniques; Infant; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Thymidine Kinase

1987
Alpha-2 antiplasmin in acute nonlymphoblastic leukemia.
    Acta haematologica, 1989, Volume: 81, Issue:3

    Topics: alpha-2-Antiplasmin; Antineoplastic Combined Chemotherapy Protocols; Antithrombin III; Cytarabine; Disseminated Intravascular Coagulation; Fibrinolysis; Humans; Idarubicin; Leukemia, Myeloid, Acute; Plasminogen; Prognosis; Remission Induction

1989
The results of treatment of selected patients with ANLL with low-dose Ara-C.
    Folia haematologica (Leipzig, Germany : 1928), 1989, Volume: 116, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

1989
OAP combination in the treatment of elderly leukaemic patients with preexisting severe internal disease.
    Folia haematologica (Leipzig, Germany : 1928), 1989, Volume: 116, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Prednisone; Risk Factors; Vincristine

1989
Clinical studies on aclacinomycin A cardiotoxicity in adult patients with acute non lymphoblastic leukaemia.
    Folia haematologica (Leipzig, Germany : 1928), 1989, Volume: 116, Issue:2

    Topics: Aclarubicin; Adult; Arrhythmias, Cardiac; Cytarabine; Electrocardiography; Female; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male

1989
Diaziquone and 2,2'-anhydro-arabinosyl-5-fluorocytosine for the treatment of children with relapsed or refractory acute nonlymphoblastic leukemia.
    Cancer, 1989, Dec-15, Volume: 64, Issue:12

    Topics: Adolescent; Ancitabine; Antineoplastic Agents; Aziridines; Benzoquinones; Bone Marrow; Cell Survival; Child; Child, Preschool; Cytarabine; Drug Administration Schedule; Drug Evaluation; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male

1989
Acute nonlymphocytic leukemia: evidence of clonogenic cells in peripheral blood in early complete remission.
    Acta haematologica, 1989, Volume: 82, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukapheresis; Leukemia, Myeloid, Acute; Leukocytes, Mononuclear; Male; Remission Induction; Translocation, Genetic

1989
Acute myeloid leukaemia presenting with pleural effusions.
    Clinical and laboratory haematology, 1989, Volume: 11, Issue:4

    Topics: Antigens, Differentiation; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Diagnosis, Differential; Histocompatibility Antigens; Humans; Leukemia, Myeloid, Acute; Leukocyte Common Antigens; Lymph Nodes; Lymphoma; Male; Middle Aged; Mitoxantrone; Pleural Effusion; Remission Induction

1989
Maturation induction in freshly isolated human myeloid leukemic cells, 1.25 (OH)2 vitamin D3 being the most potent inducer.
    Leukemia research, 1989, Volume: 13, Issue:7

    Topics: Adult; Aged; Cell Differentiation; Cell Separation; Cholecalciferol; Cytarabine; Dimethyl Sulfoxide; Female; Granulocytes; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Monocytes; Neoplastic Stem Cells; Tretinoin; Tumor Cells, Cultured

1989
[Hepatocellular carcinoma treated with a curative segmentectomy five years after complete remission of acute myeloblastic leukemia].
    Gan no rinsho. Japan journal of cancer clinics, 1989, Volume: 35, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Combined Modality Therapy; Cytarabine; Daunorubicin; Embolization, Therapeutic; Hepatectomy; Hepatitis B Surface Antigens; Humans; Leukemia, Myeloid, Acute; Liver Neoplasms; Male; Mercaptopurine; Middle Aged; Neoplasms, Multiple Primary; Prednisolone; Remission Induction

1989
Accidental overdose of mitoxantrone in three patients.
    Medical oncology and tumor pharmacotherapy, 1989, Volume: 6, Issue:4

    Topics: Adult; Aged; Breast Neoplasms; Carcinoma, Small Cell; Cytarabine; Drug Overdose; Drug Tolerance; Female; Humans; Leukemia, Myeloid, Acute; Male; Mitoxantrone

1989
The optimization of collection of peripheral blood stem cells for autotransplantation in acute myeloid leukaemia.
    Bone marrow transplantation, 1989, Volume: 4, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Blood Component Removal; Bone Marrow Diseases; Cell Count; Combined Modality Therapy; Cytarabine; Daunorubicin; Evaluation Studies as Topic; Hematopoiesis; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Retrospective Studies; Thioguanine; Transplantation, Autologous

1989
The role of peripheral blood stem cells as rescue after myeloablative therapy.
    Bone marrow transplantation, 1989, Volume: 4 Suppl 1

    Topics: Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Blood Transfusion; Combined Modality Therapy; Cytarabine; Daunorubicin; Evaluation Studies as Topic; Graft Survival; Hematopoietic Stem Cell Transplantation; Humans; Leukapheresis; Leukemia, Myeloid, Acute; Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Transplantation, Autologous

1989
Leukaemia Research Fund international research symposium on cytotoxic drug resistance in leukemia and other malignancies.
    Leukemia, 1989, Volume: 3, Issue:6

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Biological Transport; Cisplatin; Congresses as Topic; Cytarabine; DNA; Drug Resistance; Gene Amplification; Glutathione Transferase; Humans; Leukemia; Leukemia, Myeloid, Acute; Neoplasms; Nucleosides; Oxygen; Phenotype; Topoisomerase II Inhibitors; Tumor Cells, Cultured

1989
[Intensive post-remission therapy of acute myeloid leukemia with high doses of cytosine arabinoside].
    Casopis lekaru ceskych, 1989, Sep-22, Volume: 128, Issue:39

    Topics: Adolescent; Adult; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Remission Induction

1989
Idarubicin in combination with intermediate-dose cytarabine in the treatment of refractory or relapsed acute leukemias.
    European journal of haematology, 1989, Volume: 43, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Idarubicin; Leukemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma

1989
A comparison of two assays for the in vitro chemosensitivity testing of human acute non-lymphoblastic leukemia cells.
    Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:5

    Topics: Adult; Aged; Colorimetry; Cytarabine; Daunorubicin; Drug Screening Assays, Antitumor; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Tetrazolium Salts; Thymidine; Tumor Cells, Cultured

1989
Efficient formation of cytosine arabinoside-5'-triphosphate in leukemic blasts of human T-cell acute lymphoblastic leukemia.
    Leukemia research, 1989, Volume: 13, Issue:10

    Topics: Adolescent; Adult; Antigens, CD; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cytarabine; Humans; Interphase; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone

1989
[Late results of the treatment of acute granulocytic leukemia in adults].
    Terapevticheskii arkhiv, 1989, Volume: 61, Issue:7

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Doxorubicin; Drug Evaluation; Drug Resistance; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisolone; Prednisone; Remission Induction; Vincristine

1989
Alpha-streptococcal septicemia in leukemic children treated with continuous or large dosage intermittent cytosine arabinoside.
    The Pediatric infectious disease journal, 1989, Volume: 8, Issue:11

    Topics: Anti-Bacterial Agents; Child; Cytarabine; Humans; Immune Tolerance; Leukemia, Myeloid, Acute; Pulmonary Fibrosis; Retrospective Studies; Sepsis; Shock, Septic; Streptococcal Infections

1989
[Chemotherapy of adult ANLL].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1989, Volume: 30, Issue:8

    Topics: Aclarubicin; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Daunorubicin; Drug Evaluation; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Mitoxantrone; Prednisolone; Remission Induction; Survival Rate; Vincristine

1989
[The curative treatment of adult acute nonlymphocytic leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1989, Volume: 30, Issue:8

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Daunorubicin; Drug Evaluation; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisolone; Remission Induction

1989
[Comparison of conventional chemotherapy and short-term intensive chemotherapy in adult acute myeloid leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1989, Volume: 30, Issue:8

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisolone; Remission Induction; Survival Rate

1989
Standard induction and low dose ara-C treatment in patients over 60 with AML or MDS.
    The Netherlands journal of medicine, 1989, Volume: 35, Issue:3-4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Evaluation; Female; Humans; Leukemia, Myeloid, Acute; Male; Myelodysplastic Syndromes; Retrospective Studies

1989
Low-dose arabinosyl cytosine therapy of AML may be effective after failure of high or conventional doses.
    Nouvelle revue francaise d'hematologie, 1989, Volume: 31, Issue:4

    Topics: Adult; Bone Marrow; Bone Marrow Transplantation; Child; Combined Modality Therapy; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Male; Middle Aged; Remission Induction

1989
Amsacrine, cytarabine and etoposide in the treatment of bad prognosis acute myeloid leukemia.
    Medical oncology and tumor pharmacotherapy, 1989, Volume: 6, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Remission Induction; Survival Rate

1989
Phenotype switch in acute leukemia patients after intensive chemotherapy.
    Haematology and blood transfusion, 1989, Volume: 32

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Phenotype; Precursor Cell Lymphoblastic Leukemia-Lymphoma

1989
Preliminary results of an induction combination regimen including fractionated anthracycline.
    Bone marrow transplantation, 1989, Volume: 4 Suppl 3

    Topics: Aclarubicin; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Evaluation; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

1989
[Leukemic clonogenic assay and drug sensitivity test of homoharringtonine and cytarabine in acute myeloid leukemia].
    Zhonghua nei ke za zhi, 1989, Volume: 28, Issue:12

    Topics: Alkaloids; Bone Marrow; Colony-Forming Units Assay; Cytarabine; Harringtonines; Homoharringtonine; Humans; Leukemia, Myeloid, Acute; Prognosis; Tumor Stem Cell Assay

1989
The use of bone marrow cells grown in long-term culture for autologous bone marrow transplantation in acute myeloid leukaemia: an update.
    Bone marrow transplantation, 1989, Volume: 4, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cells, Cultured; Combined Modality Therapy; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Pilot Projects; Remission Induction; Risk; Thioguanine; Transplantation, Autologous

1989
Treatment of acute myelogenous leukemia. An EBMT-EORTC retrospective analysis of chemotherapy versus allogeneic or autologous bone marrow transplantation.
    European journal of cancer & clinical oncology, 1989, Volume: 25, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Doxorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Retrospective Studies; Transplantation, Autologous; Transplantation, Homologous; Vincristine

1989
Autologous bone marrow transplantation in patients with AML in second complete remission (CR).
    Bone marrow transplantation, 1989, Volume: 4 Suppl 1

    Topics: Adolescent; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmustine; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Etoposide; Evaluation Studies as Topic; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Remission Induction; Transplantation, Autologous

1989
Double autologous bone marrow transplantation in acute myeloid leukaemia.
    Bone marrow transplantation, 1989, Volume: 4 Suppl 1

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmustine; Combined Modality Therapy; Cytarabine; Doxorubicin; Evaluation Studies as Topic; Female; Humans; Leukemia, Myeloid, Acute; Male; Methods; Middle Aged; Myelodysplastic Syndromes; Thioguanine; Transplantation, Autologous

1989
Treatment of relapsed and refractory acute leukaemia with high-dose cytosine arabinoside and etoposide.
    Cancer chemotherapy and pharmacology, 1989, Volume: 23, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence

1989
Therapeutic medical reasoning.
    Journal of the Tennessee Medical Association, 1989, Volume: 82, Issue:4

    Topics: Adolescent; Cesarean Section; Cytarabine; Daunorubicin; Decision Making; Decision Support Techniques; Female; Humans; Judgment; Leukemia, Myeloid, Acute; Pregnancy; Pregnancy Complications, Neoplastic

1989
Granulocyte-macrophage colony-stimulating factor enhances the cytotoxic effects of cytosine arabinoside in acute myeloblastic leukemia and in the myeloid blast crisis phase of chronic myeloid leukemia.
    Leukemia, 1989, Volume: 3, Issue:5

    Topics: Blast Crisis; Cell Division; Colony-Stimulating Factors; Cytarabine; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Humans; Interphase; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Tumor Cells, Cultured

1989
Cures of leukemia with aggressive postremission treatment: an update of timed sequential therapy (Ac-D-Ac).
    Leukemia, 1989, Volume: 3, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute

1989
Treatment of acute nonlymphocytic leukemia in the elderly with intermediate high-dose cytosine arabinoside.
    Medical and pediatric oncology, 1989, Volume: 17, Issue:2

    Topics: Age Factors; Aged; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Random Allocation

1989
Patient-specific dose rate for continuous infusion high-dose cytarabine in relapsed acute myelogenous leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1989, Volume: 7, Issue:5

    Topics: Adult; Arabinofuranosylcytosine Triphosphate; Cytarabine; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

1989
Low dose cytosine arabinoside in adult acute non-lymphoid leukemia.
    Bone marrow transplantation, 1989, Volume: 4 Suppl 1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cytarabine; Drug Evaluation; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction

1989
Idarubicin in combination with etoposide and cytarabine in adult acute non-lymphoblastic leukaemia (ANLL).
    Bone marrow transplantation, 1989, Volume: 4 Suppl 1

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Evaluation; Etoposide; Humans; Idarubicin; Leukemia, Myeloid, Acute; Middle Aged; Remission Induction

1989
Fractionated anthracycline therapy in acute myeloblastic leukaemia in adults.
    Cancer chemotherapy and pharmacology, 1989, Volume: 23, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Pressure; Cytarabine; Daunorubicin; Drug Administration Schedule; Heart Ventricles; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Middle Aged; Thioguanine

1989
Pharmacokinetics of daunorubicin and doxorubicin in plasma and leukemic cells from patients with acute nonlymphoblastic leukemia.
    Therapeutic drug monitoring, 1989, Volume: 11, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; DNA; DNA Adducts; Doxorubicin; Humans; Leukemia, Myeloid, Acute; Metabolic Clearance Rate

1989
Respiratory insufficiency in acute leukemia following treatment with cytosine arabinoside and septicemia with streptococcus viridans.
    European journal of haematology, 1989, Volume: 42, Issue:4

    Topics: Acute Disease; Adult; Cytarabine; Female; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Respiratory Insufficiency; Sepsis; Streptococcal Infections

1989
[Treatment of patients with acute nonlymphoblastic leukemia with low doses of cytarabine].
    Gematologiia i transfuziologiia, 1989, Volume: 34, Issue:1

    Topics: Aged; Cytarabine; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction

1989
[Low doses of cytarabine in the treatment of acute non-lymphoblastic leukemia in adults].
    Gematologiia i transfuziologiia, 1989, Volume: 34, Issue:1

    Topics: Adolescent; Adult; Aged; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

1989
Attenuated high-dose cytosine arabinoside in the treatment of the elderly patient with acute nonlymphocytic leukemia. An Eastern Cooperative Oncology Group Pilot Study.
    American journal of clinical oncology, 1989, Volume: 12, Issue:3

    Topics: Aged; Cytarabine; Drug Administration Schedule; Humans; Leukemia, Myeloid, Acute; Pilot Projects; Remission Induction

1989
[Cancer curable by chemotherapy: acute myelogenous leukemia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:4 Pt 2-2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Daunorubicin; Drug Evaluation; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Leukocyte Count; Leukopenia; Mercaptopurine; Prednisolone; Prognosis; Remission Induction

1989
[4'-(9-acridinylamino)-methanesulfon-m-aniside (AMSA) combination salvage therapy in refractory acute non-lymphocytic leukemia in adults].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:5

    Topics: Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Evaluation; Drug Resistance; Female; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Leukopenia; Male; Middle Aged; Prednisolone; Remission Induction; Thioguanine; Thrombocytopenia

1989
Liquid-chromatographic monitoring of cytosine arabinoside and its metabolite, uracil arabinoside, in serum.
    Clinical chemistry, 1989, Volume: 35, Issue:6

    Topics: Aged; Arabinofuranosyluracil; Chromatography, High Pressure Liquid; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Spectrophotometry, Ultraviolet; Uridine

1989
[Differentiation induction of myeloid leukemia cells by glucocorticoid--the differentiation induction effect in vitro and in vivo].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1989, Volume: 30, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cell Differentiation; Cell Survival; Cytarabine; Dexamethasone; Female; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisolone; Remission Induction; Tumor Cells, Cultured

1989
["AB-Triple V" therapy of relapsed or refractory acute myelogenous leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1989, Volume: 30, Issue:2

    Topics: Aclarubicin; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Evaluation; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Remission Induction; Vinblastine; Vincristine; Vindesine

1989
[Remission induction treatment in adults with acute myeloid leukemia. 8-year experience with 2 successive protocols].
    Medicina clinica, 1989, Apr-29, Volume: 92, Issue:16

    Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Doxorubicin; Female; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Prednisolone; Prognosis; Remission Induction; Vincristine

1989
[Recurrence or therapeutic resistance of acute myelogenous leukemia. Effect of mitoxantrone and cytosine arabinoside].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1989, Jun-30, Volume: 109, Issue:19-21

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Resistance; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Neoplasm Recurrence, Local

1989
[An aged patient with acute myelogenous leukemia complicated with liver cirrhosis: successful treatment with low-dose cytosine arabinoside].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:7

    Topics: Aged; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Liver Cirrhosis; Remission Induction

1989
Necrotizing fasciitis of the vulva during chemotherapy.
    Obstetrics and gynecology, 1989, Volume: 74, Issue:3 Pt 2

    Topics: Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Fasciitis; Female; Humans; Leukemia, Myeloid, Acute; Necrosis; Thioguanine; Vulva; Vulvar Diseases

1989
Clinical significance of fibrinopeptide A in acute lymphocytic and non-lymphocytic leukaemia.
    Blut, 1989, Volume: 59, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Daunorubicin; Disseminated Intravascular Coagulation; Female; Fibrinogen; Fibrinopeptide A; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Longitudinal Studies; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radioimmunoassay; Thioguanine; Time Factors

1989
Acral erythema and systemic toxicity related to CHA induction therapy in acute myeloid leukemia.
    European journal of cancer & clinical oncology, 1989, Volume: 25, Issue:8

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Doxorubicin; Erythema; Female; Foot Dermatoses; Hand Dermatoses; Humans; Leukemia, Myeloid, Acute; Lomustine; Male; Middle Aged; Prognosis; Remission Induction

1989
Behenoyl cytosine arabinoside, aclacinomycin A, 6-mercaptopurine, and prednisolone combination therapy for acute non-lymphocytic leukaemia in adults.
    European journal of haematology, 1989, Volume: 43, Issue:1

    Topics: Aclarubicin; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisolone

1989
[The continuous-DCMP therapy for acute nonlymphocytic leukemia in elderly patients--comparison with younger patients].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1989, Volume: 30, Issue:4

    Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisolone

1989
The association between high-dose cytarabine neurotoxicity and renal insufficiency.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1989, Volume: 7, Issue:10

    Topics: Acute Kidney Injury; Alcoholism; Cytarabine; Female; Humans; Hyperbilirubinemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Nervous System Diseases; Risk Factors

1989
Growth factors influence the sensitivity of leukemic stem cells to cytosine arabinoside in culture.
    Blood, 1989, Volume: 73, Issue:5

    Topics: Adult; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Colony-Stimulating Factors; Cytarabine; Doxorubicin; Female; Humans; Leukemia, Myeloid, Acute; Middle Aged; Neoplastic Stem Cells; Tumor Cells, Cultured; Tumor Stem Cell Assay

1989
[Low-dose cytosine arabinoside in treatment of 17 patients with acute nonlymphocytic leukemia].
    Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, 1989, Volume: 20, Issue:1

    Topics: Adolescent; Adult; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

1989
Efficacy of intensive chemotherapy for acute myelogenous leukemia associated with a preleukemic syndrome.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1989, Volume: 7, Issue:11

    Topics: Age Factors; Anemia, Aplastic; Anemia, Refractory, with Excess of Blasts; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Multivariate Analysis; Neural Tube Defects; Preleukemia; Prognosis; Regression Analysis; Survival Rate; Thioguanine

1989
[Neutropenic enterocolitis in adults with acute leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1989, Volume: 30, Issue:7

    Topics: Adult; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Cytarabine; Daunorubicin; Enterocolitis, Pseudomembranous; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Neutropenia; Prednisolone

1989
Interaction between retinoic acid and cytosine arabinoside affecting the blast cells of acute myeloblastic leukemia.
    Leukemia, 1989, Volume: 3, Issue:11

    Topics: Cell Survival; Cytarabine; DNA; Doxorubicin; Drug Interactions; Leukemia, Myeloid, Acute; Neoplastic Stem Cells; Tretinoin; Tumor Cells, Cultured

1989
Increased proteolysis of antithrombin III Vicenza during disseminated intravascular coagulation in acute leukemia.
    Thrombosis research, 1989, Sep-01, Volume: 55, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Antithrombin III; Antithrombin III Deficiency; Cytarabine; Daunorubicin; Disseminated Intravascular Coagulation; Female; Fibrin Fibrinogen Degradation Products; Fibrinogen; Humans; Leukemia, Myeloid, Acute; Thioguanine; Thrombin; Thrombophlebitis

1989
Inappropriate increase in erythropoietin titers during chemotherapy.
    American journal of hematology, 1989, Volume: 32, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Asparaginase; Cyclophosphamide; Cytarabine; Daunorubicin; Erythropoietin; Female; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Vincristine

1989
Mitozantrone and high-dose cytarabine in adult acute myeloid leukaemia.
    Lancet (London, England), 1985, Jun-15, Volume: 1, Issue:8442

    Topics: Aged; Anthraquinones; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Infusions, Parenteral; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone

1985
Disturbance of blood-brain barrier after bone-marrow transplantation.
    Lancet (London, England), 1985, Aug-03, Volume: 2, Issue:8449

    Topics: Adult; Blood-Brain Barrier; Bone Marrow Transplantation; Brain; Child; Cyclosporins; Cytarabine; Female; Graft vs Host Disease; Humans; Leukemia, Myeloid, Acute; Male

1985
Mitozantrone and high-dose cytarabine in refractory adult acute myeloid leukaemia.
    Lancet (London, England), 1985, Aug-31, Volume: 2, Issue:8453

    Topics: Adult; Anthraquinones; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Leukemia, Myeloid, Acute; Mitoxantrone

1985
Very-low-dose cytarabine for myelodysplastic syndromes and acute myeloid leukaemia in the elderly.
    Lancet (London, England), 1986, Apr-26, Volume: 1, Issue:8487

    Topics: Aged; Cytarabine; Female; Humans; Infusions, Parenteral; Injections, Subcutaneous; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes

1986
Very-low-dose cytarabine for elderly patients.
    Lancet (London, England), 1986, Jun-21, Volume: 1, Issue:8495

    Topics: Adult; Age Factors; Aged; Anemia, Refractory, with Excess of Blasts; Cytarabine; Drug Administration Schedule; Humans; Leukemia, Myeloid, Acute; Middle Aged

1986
In vivo cell growth and pharmacologic determinants of clinical response in acute myelogenous leukemia.
    Blood, 1989, Volume: 73, Issue:1

    Topics: Adult; Aged; Bone Marrow; Cell Division; Cytarabine; DNA; Humans; Interphase; Intracellular Fluid; Leukemia, Myeloid, Acute; Middle Aged; Remission Induction

1989
Phase II trial of intermediate dose ARA-C (IDAC) with sequential mitoxantrone (MITOX) in acute myelogenous leukemia.
    Leukemia, 1989, Volume: 3, Issue:2

    Topics: Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation; Female; Humans; Leukemia, Myeloid, Acute; Male; Mitoxantrone

1989
Low-dose cytosine arabinoside in acute non-lymphoblastic leukemia.
    Cancer, 1989, Feb-01, Volume: 63, Issue:3

    Topics: Adolescent; Adult; Cytarabine; Drug Evaluation; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Thrombocytopenia

1989
Acute myelogenous leukemia treated with daunomycin associated with nephrotic syndrome.
    Nephron, 1989, Volume: 51, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Kidney; Leukemia, Myeloid, Acute; Male; Nephrotic Syndrome

1989
High-dose cytosine arabinoside and daunorubicin as primary therapy in elderly patients with acute myelogenous leukemia. A phase I-II study of the Southeastern Cancer Study Group.
    Cancer, 1989, Mar-15, Volume: 63, Issue:6

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemical and Drug Induced Liver Injury; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Evaluation; Female; Humans; Infections; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction

1989
Drug-induced toxicities associated with high-dose cytosine arabinoside infusions.
    Pharmacotherapy, 1989, Volume: 9, Issue:1

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Central Nervous System Diseases; Cytarabine; Eye Diseases; Female; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged; Retrospective Studies; Risk Factors; Skin Diseases

1989
The frequency of long-term remission in patients with acute myelogenous leukaemia treated with conventional maintenance chemotherapy: a study of 760 patients with a minimal follow-up time of 6 years.
    British journal of haematology, 1989, Volume: 71, Issue:2

    Topics: Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Middle Aged; Remission Induction; Time Factors

1989
Idarubicin plus cytarabine as first-line treatment of acute nonlymphoblastic leukemia.
    Seminars in oncology, 1989, Volume: 16, Issue:1 Suppl 2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Remission Induction

1989
[Treatment of acute myeloblastic leukemia with low-dose cytarabine].
    Presse medicale (Paris, France : 1983), 1985, Dec-14, Volume: 14, Issue:43

    Topics: Adult; Aged; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

1985
In vivo differentiation of leukaemic blasts and effect of low dose Ara-C in a marrow grafted patient with leukaemic relapse.
    British journal of haematology, 1986, Volume: 62, Issue:4

    Topics: Adult; Bone Marrow; Bone Marrow Transplantation; Cell Differentiation; Cytarabine; Female; Humans; Isoenzymes; Leukemia, Myeloid, Acute; Phosphoglucomutase

1986
[Clinical observation on the effect of an AOAP regimen in acute non-lymphatic leukemia].
    Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, 1986, Volume: 6, Issue:10

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Medicine, Chinese Traditional; Medicine, East Asian Traditional; Middle Aged; Plant Extracts; Plants, Medicinal; Prednisone; Vincristine

1986
Painful red hands: a side-effect of leukaemia therapy.
    The British journal of dermatology, 1988, Volume: 119, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Doxorubicin; Drug Eruptions; Female; Foot Dermatoses; Hand Dermatoses; Humans; Leukemia, Myeloid, Acute; Middle Aged; Pain; Thioguanine

1988
Adenosine diphosphate ribosyl transferase in marrow cells of patients with acute myeloid leukemia is related to differentiation and drug sensitivity.
    Carcinogenesis, 1985, Volume: 6, Issue:7

    Topics: Bone Marrow; Cell Differentiation; Cell Division; Clinical Enzyme Tests; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Nucleotidyltransferases; Poly(ADP-ribose) Polymerases; Prognosis; Tumor Stem Cell Assay

1985
Peripheral neuropathy after high-dose cytosine arabinoside, daunorubicin, and asparaginase consolidation for acute nonlymphocytic leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1986, Volume: 4, Issue:1

    Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Peripheral Nervous System Diseases

1986
Acute myelogenous leukemia of unfavourable prognosis treated with retinoic acid, vitamin D3, alpha-interferon and low doses of cytosine arabinoside.
    Scandinavian journal of haematology. Supplementum, 1986, Volume: 44

    Topics: Aged; Bone Marrow; Child; Cholecalciferol; Combined Modality Therapy; Cytarabine; Female; Follow-Up Studies; Humans; Interferon Type I; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Tretinoin

1986
Measurement of myeloid maturation by flow cytochemistry in HL-60 leukemia: esterase is inducible, myeloperoxidase is not.
    Cytometry, 1986, Volume: 7, Issue:3

    Topics: Cell Line; Cell Survival; Cytarabine; Dimethyl Sulfoxide; Enzyme Induction; Esterases; Flow Cytometry; Granulocytes; Histocytochemistry; Humans; Leukemia, Myeloid, Acute; Monocytes; Peroxidase; Vitamin A

1986
Study of differentiation of fresh myeloid leukemic cells by physiologic agents that induce a human promyelocytic leukemic line (HL-60) to differentiate.
    Leukemia research, 1986, Volume: 10, Issue:6

    Topics: Bucladesine; Cell Cycle; Cell Differentiation; Cell Line; Cells, Cultured; Cytarabine; Dinoprostone; Esterases; Humans; In Vitro Techniques; Leukemia, Myeloid, Acute; Nitroblue Tetrazolium; Prostaglandins E; Receptors, Formyl Peptide; Receptors, Immunologic; Theophylline; Vitamin D

1986
Bone-marrow regeneration after therapy-induced hypoplasia monitored by serum measurements of lactoferrin, lysozyme and myeloperoxidase.
    Scandinavian journal of haematology, 1986, Volume: 37, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Daunorubicin; Doxorubicin; Hematopoiesis; Humans; Lactoferrin; Lactoglobulins; Leukemia, Myeloid, Acute; Leukocyte Count; Muramidase; Neutrophils; Peroxidase; Prednisolone; Thioguanine; Time Factors; Vincristine

1986
Deoxycytidine kinase and deoxycytidine deaminase values correspond closely to clinical response to cytosine arabinoside remission induction therapy in patients with acute myelogenous leukemia.
    Seminars in oncology, 1987, Volume: 14, Issue:2 Suppl 1

    Topics: Adolescent; Adult; Age Factors; Cytarabine; Cytidine Deaminase; Deoxycytidine Kinase; Humans; Leukemia, Myeloid, Acute; Middle Aged; Nucleoside Deaminases; Phosphotransferases

1987
Intermediate and high dose Ara-C and m-AMSA for remission induction and consolidation treatment of patients with acute myeloid leukemia: an EORTC Leukemia Cooperative Group phase II study.
    European journal of cancer & clinical oncology, 1988, Volume: 24, Issue:11

    Topics: Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Drug Evaluation; Humans; Leukemia, Myeloid, Acute; Middle Aged; Prognosis; Remission Induction

1988
GM-CSF enhances sensitivity of leukemic clonogenic cells to long-term low dose cytosine arabinoside with sparing of the normal clonogenic cells.
    Behring Institute Mitteilungen, 1988, Issue:83

    Topics: Bone Marrow; Cell Survival; Colony-Forming Units Assay; Colony-Stimulating Factors; Cytarabine; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Humans; Leukemia, Myeloid, Acute; Placenta; Pregnancy; Recombinant Proteins; Tumor Cells, Cultured; Tumor Stem Cell Assay

1988
Long term results in acute non-lymphocytic leukaemia.
    The Journal of the Association of Physicians of India, 1988, Volume: 36, Issue:8

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Doxorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male

1988
Low-dose ARA-C in acute leukemias. Analysis of 30 cases.
    Chinese medical journal, 1986, Volume: 99, Issue:10

    Topics: Adolescent; Adult; Cytarabine; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Middle Aged

1986
[Chemotherapy of medium-to-large doses in the treatment of acute leukemia: report of 16 cases].
    Zhonghua yi xue za zhi, 1987, Volume: 67, Issue:7

    Topics: Adolescent; Adult; Cytarabine; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged

1987
Immunological erythroblastopenia induced by HCO-60 as a solvent of enocitabine (BH-AC).
    Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society, 1987, Volume: 50, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Castor Oil; Cytarabine; Erythroblasts; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Male; Red-Cell Aplasia, Pure; Solvents

1987
Curative effect of harringtonine semisynthetic harringtonine and HOAP on nonlymphocytic leukemias. Analysis of 304 cases.
    Chinese medical journal, 1987, Volume: 100, Issue:7

    Topics: Adult; Alkaloids; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Cytarabine; Female; Harringtonines; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisone; Vincristine

1987
Comparison of results of salvage therapy in adult acute myelogenous leukemia.
    Acta haematologica, 1987, Volume: 78 Suppl 1

    Topics: Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Doxorubicin; Drug Evaluation; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Prednisone; Prognosis; Prospective Studies; Recurrence; Regression Analysis; Retrospective Studies; Vincristine

1987
All-trans retinoic acid with or without low dose cytosine arabinoside in acute promyelocytic leukemia. Report of 6 cases.
    Chinese medical journal, 1987, Volume: 100, Issue:12

    Topics: Adult; Child; Child, Preschool; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Tretinoin

1987
Differentiation of human leukaemic cell lines and fresh leukaemia cells by low dose Ara-C: monitoring by expression of c-myc and c-fos oncogenes.
    Medical oncology and tumor pharmacotherapy, 1988, Volume: 5, Issue:2

    Topics: Cell Differentiation; Cell Line, Transformed; Cytarabine; DNA, Neoplasm; Humans; Leukemia, Myeloid, Acute; Nucleic Acid Hybridization; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-myc; Proto-Oncogenes; Transcription, Genetic; Tumor Cells, Cultured

1988
Second long-term remission achieved with low-dose Ara-C in children with relapsed acute nonlymphoblastic leukemia.
    Pediatric hematology and oncology, 1987, Volume: 4, Issue:3

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Remission Induction; Thioguanine

1987
Treatment of childhood acute nonlymphocytic leukemia with high-dose cytosine arabinoside, 6-thioguanine, and doxorubicin without maintenance therapy: pilot study ANLL-80 of the Dutch Childhood Leukemia Study Group (DCLSG).
    Pediatric hematology and oncology, 1988, Volume: 5, Issue:2

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Doxorubicin; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Netherlands; Pilot Projects; Remission Induction; Thioguanine

1988
Cytotoxic action of low dose Ara-C. Investigations in a marrow grafted patient with relapse.
    Onkologie, 1985, Volume: 8, Issue:3

    Topics: Adult; Bone Marrow; Bone Marrow Transplantation; Cell Transformation, Neoplastic; Combined Modality Therapy; Cytarabine; Female; Humans; Isoenzymes; Leukemia, Myeloid, Acute; Phosphoglucomutase

1985
[Combination of AMSA-high dose cytosine arabinoside in acute leukemia].
    Presse medicale (Paris, France : 1983), 1985, Jun-29, Volume: 14, Issue:26

    Topics: Adolescent; Adult; Aged; Aminoacridines; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged

1985
[Relation between plasma Ara-C and intracellular Ara-CTP levels by intermediate dose and high dose Ara-C administration in the treatment of AML].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:4 Pt 1

    Topics: Adult; Aged; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Bone Marrow; Bone Marrow Cells; Cytarabine; Humans; Leukemia, Myeloid, Acute; Middle Aged

1988
Results of induction and consolidation treatment with intermediate and high-dose cytosine arabinoside and m-Amsa of patients with poor-risk acute myelogenous leukaemia.
    European journal of haematology, 1988, Volume: 40, Issue:3

    Topics: Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Risk Factors

1988
Metabolism, incorporation into DNA, and interactions with 1-beta-D-arabinofuranosylcytosine of 5-hydroxymethyl-2'-deoxyuridine in human promyelocytic leukemia cells (HL-60).
    Cancer research, 1988, Jun-01, Volume: 48, Issue:11

    Topics: Cell Line; Cell Survival; Cytarabine; DNA, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Kinetics; Leukemia, Myeloid, Acute; Thymidine

1988
High-dose retinol in children with acute myelogenous leukemia in remission.
    European journal of haematology, 1988, Volume: 40, Issue:5

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Doxorubicin; Drug Administration Schedule; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Remission Induction; Thioguanine; Vitamin A

1988
[Effect of low-dose Ara-C regimen on myelodysplastic syndrome (MDS)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:4 Pt 2-2

    Topics: Aged; Cytarabine; Female; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Remission Induction

1988
[Pharmacokinetic studies of N4-behenoyl-1-beta-D-arabinofuranosylcytosine (BH-AC) by 30-minute infusion with acute nonlymphocytic leukemia--the possibility of administration for outpatients].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:6

    Topics: Adult; Ambulatory Care; Antineoplastic Agents; Cytarabine; Female; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged

1988
[Acute leukemia subsequent to sideroblastic anemia: response to low dose cytosine arabinoside].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1988, Volume: 29, Issue:1

    Topics: Adult; Anemia, Sideroblastic; Blast Crisis; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute

1988
Mitoxantrone and high-dose cytosine arabinoside in refractory acute myelogenous leukemia.
    Cancer, 1988, Aug-15, Volume: 62, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Remission Induction

1988
[Aclarubicin-related pancreatitis in a child with AML].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1988, Volume: 29, Issue:3

    Topics: Aclarubicin; Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Naphthacenes; Pancreatitis; Vincristine

1988
[Coexistence of tuberculosis of the lymph nodes and myeloblastic leukemia].
    Pneumonologia polska, 1988, Volume: 56, Issue:3

    Topics: Antitubercular Agents; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Middle Aged; Tuberculosis, Lymph Node

1988
Severe persistent cerebellar dysfunction complicating cytosine arabinoside therapy.
    Acta medica Scandinavica, 1988, Volume: 224, Issue:2

    Topics: Adult; Cerebellar Diseases; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Purkinje Cells

1988
Short remission durations in therapy-related leukemia despite cytogenetic complete responses to high-dose cytarabine.
    Blood, 1988, Volume: 72, Issue:4

    Topics: Adult; Aged; Biopsy, Needle; Bone Marrow; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Remission Induction

1988
Acute leukemia occurring after radiotherapy and chemotherapy with a nitrosourea, PCNU.
    Investigational new drugs, 1988, Volume: 6, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Agents; Cytarabine; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Nitrosourea Compounds; Rectal Neoplasms; Translocation, Genetic

1988
Low dose cytosine arabinoside in the treatment of myeloid leukaemias and myelodysplastic syndromes.
    Irish journal of medical science, 1988, Volume: 157, Issue:7

    Topics: Aged; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Primary Myelofibrosis

1988
[High dosage and intermediate dosage cytosine arabinoside in the treatment of secondary leukemias].
    Wiener klinische Wochenschrift, 1988, Aug-05, Volume: 100, Issue:15

    Topics: Adult; Alkylating Agents; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Leukemia, Radiation-Induced; Male; Middle Aged; Remission Induction

1988
[BH-AC.AMP protocol in the treatment of refractory childhood acute leukemia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:10

    Topics: Aclarubicin; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Drug Administration Schedule; Female; Humans; Infant; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Lymphoma; Male; Mercaptopurine; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction

1988
Acute adult leukemia. The Danbury Hospital experience.
    Connecticut medicine, 1988, Volume: 52, Issue:9

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Retrospective Studies; Thioguanine

1988
Treatment of "poor risk" acute nonlymphocytic leukemia with continuously infused low-dose cytosine arabinoside.
    American journal of hematology, 1988, Volume: 29, Issue:2

    Topics: Adult; Aged; Bone Marrow; Cell Count; Cytarabine; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Karyotyping; Leukemia, Myeloid, Acute; Male; Prognosis; Recurrence; Remission Induction

1988
Relationship between the in vitro sensitivity to cytosine arabinoside of blast progenitors and the outcome of treatment in acute myeloblastic leukaemia patients.
    British journal of haematology, 1988, Volume: 70, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colony-Forming Units Assay; Cytarabine; Daunorubicin; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Middle Aged

1988
[Low-dose ARA-C and HOAAP regimen in the treatment of adult acute nonlymphocytic leukemia: analysis of 59 cases].
    Zhonghua nei ke za zhi, 1988, Volume: 27, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Doxorubicin; Female; Harringtonines; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisone; Vincristine

1988
Bone marrow biopsy during induction chemotherapy for acute myeloid leukaemia identifies only 50% of patients with resistant disease.
    Leukemia research, 1988, Volume: 12, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bone Marrow; Bone Marrow Examination; Cytarabine; Daunorubicin; Drug Resistance; Humans; Leukemia, Myeloid, Acute; Remission Induction; Thioguanine

1988
[DCTP(II) combination chemotherapy of adult acute nonlymphocytic leukemia].
    Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society, 1988, Volume: 51, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Evaluation; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisolone; Remission Induction; Thioguanine

1988
[Differentiating effect of the oral administration of vitamin D and vitamin A in acute myelocytic leukemia after BHAC-DMP therapy].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1988, Volume: 29, Issue:5

    Topics: Administration, Oral; Aged; Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Prednisolone; Vitamin A; Vitamin D

1988
In vitro sensitivity of clonogenic cells in resisting and relapsing patients with acute myelogenous leukaemia.
    British journal of cancer, 1988, Volume: 58, Issue:5

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Clone Cells; Cytarabine; Daunorubicin; Drug Screening Assays, Antitumor; Humans; Leukemia, Myeloid, Acute; Middle Aged

1988
A comparative pathological study of liver injury after different combination chemotherapies for leukemia.
    Acta pathologica japonica, 1988, Volume: 38, Issue:11

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Liver; Melphalan; Prednisolone; Prednisone; Thioguanine

1988
[Abnormal karyotype, t(9;13)(q34;q12) in a patient with acute myelocytic leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1988, Volume: 29, Issue:11

    Topics: Chromosome Aberrations; Chromosome Deletion; Chromosomes, Human, Pair 13; Chromosomes, Human, Pair 6; Chromosomes, Human, Pair 9; Cytarabine; Female; Humans; Karyotyping; Leukemia, Myeloid, Acute; Middle Aged; Remission Induction

1988
[Acute graft-versus-host disease in a patient with acute myeloblastic leukemia following consolidation therapy and platelet transfusions].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1988, Volume: 29, Issue:11

    Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Daunorubicin; Female; Graft vs Host Disease; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Platelet Transfusion; Prednisolone; Transfusion Reaction

1988
[Dissociation between the effect on myeloblastoma and the hematologic effect of Ara-C therapy: report of an autopsied myeloblastic leukemia case with around five-year course].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1988, Volume: 29, Issue:12

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Daunorubicin; Drug Resistance; Female; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Remission Induction; Tumor Cells, Cultured; Uterine Neoplasms

1988
[Comparative analysis of 3 therapeutic regimens based on the combination of an anthracycline and cytosine arabinoside for remission induction in myeloblastic leukemia].
    Sangre, 1988, Volume: 33, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Daunorubicin; Doxorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisone; Remission Induction; Thioguanine; Vincristine

1988
Results of aggressive chemotherapy for myelodysplastic syndromes.
    Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society, 1988, Volume: 51, Issue:8

    Topics: Adult; Aged; Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Male; Mercaptopurine; Middle Aged; Myelodysplastic Syndromes; Prednisolone; Remission Induction; Vincristine

1988
Association between the secondary colony-plating efficiency of blast progenitors and the remission induction outcome of acute myeloblastic leukemia patients.
    Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society, 1988, Volume: 51, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Middle Aged; Neoplastic Stem Cells; Prednisolone; Prognosis; Remission Induction; Tumor Stem Cell Assay

1988
Treatment of acute non-lymphocytic leukemia with alternating non-cross resistant chemotherapy.
    Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society, 1988, Volume: 51, Issue:8

    Topics: Aclarubicin; Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Resistance; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisolone; Prognosis; Remission Induction; Vincristine

1988
[Chemotherapeutic effects in hypoplastic leukemia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:4 Pt 2-2

    Topics: Adult; Aged; Antineoplastic Agents; Cytarabine; Drug Evaluation; Humans; Immunoglobulin G; Immunotoxins; Infusions, Intravenous; Leukemia, Myeloid, Acute; Melphalan; Middle Aged; Preleukemia

1988
Interleukin 3 enhances the cytotoxic activity of 1-beta-D-arabinofuranosylcytosine (ara-C) on acute myeloblastic leukaemia (AML) cells.
    British journal of haematology, 1988, Volume: 70, Issue:1

    Topics: Cell Survival; Cytarabine; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Interleukin-1; Interleukin-3; Leukemia, Myeloid, Acute; Tumor Cells, Cultured

1988
Effect of recombinant GM-CSF on the metabolism of cytosine arabinoside in normal and leukemic human bone marrow cells.
    Leukemia, 1988, Volume: 2, Issue:12

    Topics: Bone Marrow; Cell Division; Colony-Stimulating Factors; Cytarabine; Deoxycytosine Nucleotides; Drug Synergism; Granulocytes; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Macrophages; Neoplastic Stem Cells; Recombinant Proteins

1988
[Induction and intensive combined therapy of acute myeloid leukemia in adults].
    Onkologie, 1988, Volume: 11, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dacarbazine; Daunorubicin; Dose-Response Relationship, Drug; Drug Administration Schedule; Follow-Up Studies; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Middle Aged; Nimustine; Nitrosourea Compounds; Vincristine

1988
Proto-oncogene expression in HL-60 cells exposed to ara-C.
    Seminars in oncology, 1987, Volume: 14, Issue:2 Suppl 1

    Topics: Cell Cycle; Cell Differentiation; Cell Line; Cell Survival; Cytarabine; Gene Expression Regulation; Histones; Humans; Leukemia, Myeloid, Acute; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogenes; RNA, Messenger; Triose-Phosphate Isomerase

1987
Comparison of the sensitivity of normal and leukaemic myeloid progenitors to in-vitro incubation with cytotoxic drugs: a study of pharmacological purging.
    Leukemia research, 1987, Volume: 11, Issue:11

    Topics: Antineoplastic Agents; Bone Marrow; Bone Marrow Transplantation; Cell Survival; Clone Cells; Cyclophosphamide; Cytarabine; Etoposide; Granulocytes; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Melphalan; Transplantation, Autologous; Tumor Cells, Cultured

1987
Fetal liver infusion in acute myelogenous leukaemia.
    Thymus, 1987, Volume: 10, Issue:1-2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Fetus; Humans; Leukemia, Myeloid, Acute; Liver; Liver Transplantation

1987
Autologous bone marrow transplantation for patients with acute myelogenous leukemia in complete remission.
    Annals of the New York Academy of Sciences, 1987, Volume: 511

    Topics: Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmustine; Combined Modality Therapy; Cytarabine; Etoposide; Evaluation Studies as Topic; Humans; Leukemia, Myeloid, Acute; Lymphocyte Depletion; Postoperative Complications; Remission Induction; Transplantation, Autologous

1987
Treatment of acute myeloid leukemia in elderly patients. A retrospective study.
    Cancer, 1988, Jan-15, Volume: 61, Issue:2

    Topics: Aged; Antineoplastic Agents; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Retrospective Studies

1988
Rebound peripheral blastosis with subsequent remission during remission induction in a patient with acute promyelocytic leukemia.
    Cancer, 1988, Feb-15, Volume: 61, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Female; Follow-Up Studies; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Prednisone; Vincristine

1988
[A case of complete remission from acute myelogenous leukemia in second relapse achieved using an intermediate-dose cytosine arabinoside (ID Ara-C) regimen].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:1

    Topics: Cytarabine; Drug Administration Schedule; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence

1986
The role of 13 cis-retinoic acid in the remission induction of a patient with acute promyelocytic leukemia.
    Cancer, 1986, Jan-15, Volume: 57, Issue:2

    Topics: Adult; Cell Differentiation; Cytarabine; Humans; In Vitro Techniques; Isotretinoin; Leukemia, Myeloid, Acute; Male; Tretinoin

1986
Progressive ascending paralysis following administration of intrathecal and intravenous cytosine arabinoside. A Pediatric Oncology Group study.
    Cancer, 1986, Mar-15, Volume: 57, Issue:6

    Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain; Cytarabine; Female; Humans; Injections, Intravenous; Injections, Spinal; Leukemia, Myeloid, Acute; Lung; Muscles; Paralysis; Spinal Cord; Time Factors

1986
Thrombotic thrombocytopenic purpura subsequent to acute myelogenous leukemia chemotherapy.
    American journal of hematology, 1986, Volume: 21, Issue:3

    Topics: Antineoplastic Agents; Blood Transfusion; Cytarabine; Daunorubicin; Erythrocyte Transfusion; Female; Humans; Leukemia, Myeloid, Acute; Microcirculation; Mitomycins; Platelet Transfusion; Purpura; Thrombocytopenia

1986
The sensitivity to cytosine arabinoside of the blast progenitors of acute myeloblastic leukemia.
    Blood, 1986, Volume: 67, Issue:3

    Topics: Adult; Aged; Cell Survival; Colony-Forming Units Assay; Cytarabine; Dose-Response Relationship, Drug; Doxorubicin; Humans; Leukemia, Myeloid, Acute; Methylcellulose; Middle Aged; Suspensions; Tumor Stem Cell Assay

1986
Intensive timed chemotherapy protocol for 37 resistant or relapsing acute myeloid leukemias.
    Cancer treatment reports, 1986, Volume: 70, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

1986
Does the metabolite uracil arabinoside inhibit cytosine arabinoside (Ara-C) penetration into the cerebrospinal fluid during high-dose Ara-C therapy?
    Scandinavian journal of haematology, 1986, Volume: 36, Issue:1

    Topics: Adult; Arabinofuranosyluracil; Biological Transport; Blood-Brain Barrier; Cytarabine; Half-Life; Humans; Kinetics; Leukemia, Myeloid, Acute; Male; Uridine

1986
Neurotoxicity associated with systemic high-dose cytosine arabinoside.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1986, Volume: 4, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Aged; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Nervous System Diseases

1986
High dose Ara-C related leukoencephalopathy.
    Journal of neuro-oncology, 1986, Volume: 3, Issue:4

    Topics: Adult; Brain; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Leukoencephalopathy, Progressive Multifocal; Male; Middle Aged; Time Factors; Tomography, X-Ray Computed

1986
Potentiation by 1-alpha,25-dihydroxyvitamin D3 of cytotoxicity to HL-60 cells produced by cytarabine and hydroxyurea.
    Journal of the National Cancer Institute, 1986, Volume: 76, Issue:4

    Topics: Calcitriol; Cell Differentiation; Cell Division; Cell Line; Cell Survival; Cytarabine; DNA, Neoplasm; Drug Synergism; Humans; Hydroxyurea; Leukemia, Myeloid, Acute

1986
Cellular pharmacology and optimal therapeutic concentrations of 1-beta-D-arabinofuranosylcytosine 5'-triphosphate in leukemic blasts during treatment of refractory leukemia with high-dose 1-beta-D-arabinofuranosylcytosine.
    Scandinavian journal of haematology. Supplementum, 1986, Volume: 44

    Topics: Acute Disease; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Biotransformation; Chromatography, High Pressure Liquid; Cytarabine; Humans; Kinetics; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute

1986
[Myelodysplastic syndrome and myelogenous leukemia. Treatment with low-dose cytarabine].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1986, Feb-28, Volume: 106, Issue:6

    Topics: Aged; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes

1986
[Effect of low-dose Ara-C in the treatment of refractory, atypical leukemia and myelodysplastic syndrome].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:4 Pt 1

    Topics: Adolescent; Adult; Aged; Child; Cytarabine; Drug Administration Schedule; Drug Evaluation; Female; Humans; Infusions, Parenteral; Injections, Subcutaneous; Leukemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes

1986
Treatment of TdT+ myeloid blast crisis of chronic granulocytic leukemia with low dose cytosine arabinoside.
    British journal of haematology, 1986, Volume: 62, Issue:4

    Topics: Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Middle Aged

1986
High-dose chemotherapy regimens.
    Medical hypotheses, 1986, Volume: 19, Issue:2

    Topics: Cerebellar Diseases; Cytarabine; Half-Life; Humans; Leukemia, Myeloid, Acute; Oxygen Inhalation Therapy

1986
Cerebellar dysfunction during high dose cytosine arabinoside therapy in a case of acute myelogenous leukaemia.
    Scandinavian journal of haematology, 1986, Volume: 36, Issue:2

    Topics: Cerebellar Diseases; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myeloid, Acute; Middle Aged

1986
Successful treatment of acute megakaryoblastic leukaemia.
    Scandinavian journal of haematology, 1986, Volume: 36, Issue:2

    Topics: Aclarubicin; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Blood Transfusion; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Naphthacenes; Thioguanine

1986
Acute promyelocytic leukemia. M.D. Anderson Hospital experience.
    The American journal of medicine, 1986, Volume: 80, Issue:5

    Topics: Aminoacridines; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Blood Transfusion; Cytarabine; Daunorubicin; Disseminated Intravascular Coagulation; Doxorubicin; Female; Hemorrhage; Hospitals, Teaching; Hospitals, University; Humans; Karyotyping; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Prognosis; Risk; Texas; Time Factors; Vincristine

1986
Typhlitis: selective surgical management.
    American journal of surgery, 1986, Volume: 151, Issue:5

    Topics: Adolescent; Adult; Aged; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Child; Colitis; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neutropenia; Risk

1986
1-B-D arabinofuranosyl cytosine and all-trans retinoic acid in combination accelerates and increases monocyte differentiation of myeloid leukemic cells.
    Leukemia research, 1986, Volume: 10, Issue:6

    Topics: Antibodies, Monoclonal; Cell Differentiation; Cell Line; Cells, Cultured; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Humans; In Vitro Techniques; Isomerism; Leukemia, Myeloid, Acute; Nitroblue Tetrazolium; Tretinoin

1986
Clinical experience with amphotericin B in acute myelogenous leukemia.
    Southern medical journal, 1986, Volume: 79, Issue:7

    Topics: Aged; Amphotericin B; Anti-Bacterial Agents; Aspergillosis; Cytarabine; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Infusions, Parenteral; Leukemia, Myeloid, Acute; Lung Diseases, Fungal; Male; Middle Aged; Neutropenia; Pneumonia; Retrospective Studies; Time Factors

1986
Correlation of drug sensitivity in vitro with clinical responses in childhood acute myeloid leukemia.
    Blood, 1986, Volume: 68, Issue:2

    Topics: Adolescent; Adult; Child; Child, Preschool; Colony-Forming Units Assay; Cytarabine; Daunorubicin; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Tumor Stem Cell Assay

1986
Effect of the interval between high dose 1-beta-D-arabinofuranosylcytosine injections on leukemic cell load, intestinal toxicity, and normal hematopoietic stem cells in a rat model for acute myelogenous leukemia.
    Cancer research, 1986, Volume: 46, Issue:8

    Topics: Animals; Cell Survival; Cytarabine; Female; Hematopoietic Stem Cells; Injections; Intestines; Leukemia, Myeloid, Acute; Mice; Mice, Inbred Strains; Rats; Rats, Inbred BN; Time Factors

1986
[An unusual way of manifesting acute granulocytic leukemia: granulocytic sarcoma of the breast. Apropos of a case with trisomy 22].
    Nouvelle revue francaise d'hematologie, 1986, Volume: 28, Issue:2

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chromosomes, Human, 21-22 and Y; Cytarabine; Daunorubicin; Female; Granulocytes; Humans; Karyotyping; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Neoplasms, Multiple Primary; Trisomy

1986
Relapsing process in FAB subtypes of adult acute leukemia and its relationship to treatment regimens.
    The Tohoku journal of experimental medicine, 1986, Volume: 148, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Middle Aged; Prednisolone; Time Factors

1986
Induction of differentiation in human myeloid leukemia cells with cytosine arabinoside.
    Leukemia research, 1986, Volume: 10, Issue:8

    Topics: Bone Marrow Cells; Cell Differentiation; Cytarabine; Humans; Karyotyping; Leukemia, Myeloid, Acute; Leukocyte Count

1986
Inducibility of terminal differentiation in daunomycin- and cytosine arabinoside-resistant mouse myeloid leukemia M1 cells.
    Leukemia research, 1986, Volume: 10, Issue:8

    Topics: Animals; Calcitriol; Cell Differentiation; Cell Division; Cell Line; Cytarabine; Daunorubicin; Dexamethasone; Drug Resistance; Leukemia, Myeloid, Acute; Methylnitronitrosoguanidine; Mice; Organophosphorus Compounds; Poly I; Pyridinium Compounds

1986
DNA-repair kinetics and the sensitivity of cells to X-ray-induced chromosome aberrations: a mouse myeloid leukemia cell line and normal mouse bone marrow cells.
    Mutation research, 1986, Volume: 162, Issue:2

    Topics: Animals; Bone Marrow; Cell Cycle; Cell Line; Chromosome Aberrations; Cytarabine; DNA Repair; Leukemia, Myeloid, Acute; Mice; X-Rays

1986
Phase I-II clinical and pharmacologic studies of high-dose cytosine arabinoside in refractory leukemia.
    The American journal of medicine, 1986, Volume: 81, Issue:3

    Topics: Adolescent; Adult; Aged; Brain Diseases; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lung Diseases; Male; Middle Aged

1986
[Low-dose 4N-behenoyl-1-beta-D-arabinofuranosylcytosine (BHAC) in the treatment of atypical leukemia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:9

    Topics: Adult; Aged; Antineoplastic Agents; Cytarabine; Drug Administration Schedule; Female; Humans; Infusions, Parenteral; Leukemia, Myeloid, Acute; Male; Middle Aged

1986
Early intensification and short-term maintenance chemotherapy does not prolong survival in acute myelogenous leukemia.
    Cancer, 1986, Oct-15, Volume: 58, Issue:8

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Drug Administration Schedule; Humans; Leukemia, Myeloid, Acute; Middle Aged; Prednisone; Vincristine

1986
Reversible bilateral lateral rectus muscle palsy associated with high-dose cytosine arabinoside and mitoxantrone therapy.
    Cancer, 1986, Oct-15, Volume: 58, Issue:8

    Topics: Adult; Cerebellar Diseases; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Ophthalmoplegia

1986
Treatment of acute leukaemia with m-AMSA in combination with cytosine arabinoside.
    Cancer chemotherapy and pharmacology, 1986, Volume: 18, Issue:1

    Topics: Aged; Amsacrine; Chemical and Drug Induced Liver Injury; Cytarabine; Female; Gastrointestinal Diseases; Heart Diseases; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Neutropenia; Thrombocytopenia

1986
A short-term chemosensitivity test with different labeled precursors of DNA or protein synthesis: correlation with clinical response.
    Tumori, 1986, Aug-31, Volume: 72, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; DNA; Drug Administration Schedule; Drug Evaluation, Preclinical; Humans; Leucine; Leukemia, Myeloid, Acute; Protein Biosynthesis; Thioguanine; Thymidine

1986
[Full remission of acute non-lymphatic leukemia lasting for 16 months following combination therapy with aclacinomycin A].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1986, Volume: 134, Issue:8

    Topics: Aclarubicin; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Drug Administration Schedule; Etoposide; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Naphthacenes; Thioguanine

1986
Interstitial pneumonitis due to leukaemic cell necrosis.
    The New Zealand medical journal, 1986, Oct-08, Volume: 99, Issue:811

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Diagnosis, Differential; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lung; Necrosis; Pulmonary Fibrosis

1986
Surgery for the acute abdomen in adults with leukaemia.
    Postgraduate medical journal, 1986, Volume: 62, Issue:732

    Topics: Abdomen, Acute; Adolescent; Adult; Appendectomy; Colectomy; Cytarabine; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Retrospective Studies

1986
Behenoyl cytosine arabinoside, daunorubicin, 6-mercaptopurine, and prednisolone combination therapy for acute myelogenous leukemia in adults and prognostic factors related to remission duration and survival length.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1986, Volume: 4, Issue:12

    Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisone; Prognosis; Statistics as Topic

1986
[Effectiveness and toxicity of high-dosage Ara-C. Clinical observations in 10 cases and review of the literature].
    Schweizerische medizinische Wochenschrift, 1986, Oct-11, Volume: 116, Issue:41

    Topics: Adolescent; Adult; Aged; Alopecia; Bone Marrow Diseases; Brain Diseases; Conjunctivitis; Cytarabine; Digestive System Diseases; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

1986
Control of proliferating potential of myeloid leukemia cells during long-term treatment with vitamin D3 analogues and other differentiation inducers in combination with antileukemic drugs: in vitro and in vivo studies.
    Cancer research, 1987, Jan-15, Volume: 47, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Calcitriol; Cell Differentiation; Cell Division; Cytarabine; Dactinomycin; Daunorubicin; Dexamethasone; Hydroxycholecalciferols; Leukemia, Experimental; Leukemia, Myeloid, Acute; Mice; Time Factors

1987
[High-dose cytarabine therapy in acute myeloid leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1986, Volume: 27, Issue:8

    Topics: Adolescent; Adult; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

1986
Potentiation of cytotoxicity of 1-beta-D-arabinofuranosylcytosine for K562 human leukemic cells by cadeguomycin.
    Cancer research, 1987, Feb-01, Volume: 47, Issue:3

    Topics: Anti-Bacterial Agents; Cell Division; Cell Line; Cell Survival; Cytarabine; Drug Synergism; Guanosine; Humans; Kinetics; Leukemia, Myeloid, Acute; Tritium

1987
Phase II study of mitoxantrone and cytarabine in acute myeloid leukemia.
    Cancer treatment reports, 1987, Volume: 71, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Child; Cytarabine; Drug Evaluation; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone

1987
High-dose cytosine arabinoside and mitoxantrone: a highly effective regimen in refractory acute myeloid leukemia.
    Blood, 1987, Volume: 69, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Evaluation; Drug Resistance; Heart Diseases; Humans; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Prognosis; Thioguanine

1987
Acute promyelocytic leukemia. A childhood cluster.
    Cancer, 1987, Mar-01, Volume: 59, Issue:5

    Topics: Bone Marrow; Child; Child, Preschool; Cytarabine; Epidemiologic Methods; Humans; Infant; Leukemia, Myeloid, Acute; Microscopy, Electron; South Africa; Tranexamic Acid

1987
[Multiple liver abscesses successfully treated by intraportal administration of amphotericin B in a case of AML (M2)].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1986, Volume: 27, Issue:11

    Topics: Adult; Amphotericin B; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Liver Abscess; Male; Mercaptopurine; Portal System; Prednisolone

1986
[Diagnosis and intensive treatment of acute leukemia in pregnancy].
    Medicina clinica, 1987, Jan-10, Volume: 88, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Prednisone; Pregnancy; Pregnancy Complications, Neoplastic; Thioguanine; Vincristine

1987
[Preliminary results of the treatment of various forms of non-lymphoblastic leukemia with small doses of cytosine arabinoside].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1986, Oct-27, Volume: 41, Issue:43

    Topics: Adult; Aged; Blood Cell Count; Cytarabine; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged

1986
Correlation of drug-perturbed marrow cell growth kinetics and intracellular 1-B-D-arabinofuranosylcytosine metabolism with clinical response in adult acute myelogenous leukemia.
    Blood, 1987, Volume: 69, Issue:4

    Topics: Arabinofuranosylcytosine Triphosphate; Bone Marrow; Bone Marrow Cells; Cell Cycle; Cells, Cultured; Cytarabine; DNA, Neoplasm; Drug Resistance; Humans; Leukemia, Myeloid, Acute; Prognosis

1987
Arabinosyl cytosine: a 20-year update.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Humans; Leukemia, Myeloid, Acute

1987
In-vitro studies on phosphorylation and dephosphorylation of cytosine arabinoside in human leukemic cells.
    Leukemia research, 1987, Volume: 11, Issue:4

    Topics: Bone Marrow; Cytarabine; Humans; In Vitro Techniques; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Phosphorylation

1987
[Acute myeloblastic leukemias and myelodysplasias: treatment with low doses of aracytine].
    Nouvelle revue francaise d'hematologie, 1986, Volume: 28, Issue:6

    Topics: Aged; Cytarabine; Humans; Leukemia, Myeloid, Acute; Middle Aged; Myelodysplastic Syndromes

1986
[Treatment of acute adult myeloblastic leukemia with intensive chemotherapy].
    Sangre, 1986, Volume: 31, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Carmustine; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Combinations; Drug Evaluation; Female; Humans; Leukemia, Myeloid, Acute; Male; Meningeal Neoplasms; Mercaptopurine; Methotrexate; Middle Aged; Mitoguazone; Prednisone; Thioguanine; Vincristine

1986
Hypoplastic acute leukemia: cytogenic evidence for differentiation in vivo in response to low-dose ara-C.
    British journal of haematology, 1987, Volume: 65, Issue:3

    Topics: Cell Differentiation; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

1987
Saturation of 1-beta-D-arabinofuranosylcytosine 5'-triphosphate accumulation in leukemia cells during high-dose 1-beta-D-arabinofuranosylcytosine therapy.
    Cancer research, 1987, Jun-01, Volume: 47, Issue:11

    Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Blast Crisis; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Infusions, Intravenous; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Metabolic Clearance Rate

1987
Effects on leukemic clonogenic cells in murine myeloid leukemia of 1-beta-D-arabinofuranosylcytosine and the anthracyclines adriamycin, daunomycin, aclacinomycin A, and 4'-epidoxorubicin.
    Cancer research, 1987, May-01, Volume: 47, Issue:9

    Topics: Aclarubicin; Animals; Antibiotics, Antineoplastic; Clone Cells; Colony-Forming Units Assay; Cytarabine; Daunorubicin; Doxorubicin; Epirubicin; Kinetics; Leukemia, Myeloid, Acute; Mice; Naphthacenes

1987
["A-triple-V" in refractory or relapsed acute myelocytic leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1987, Volume: 28, Issue:1

    Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Vinblastine; Vincristine

1987
Degradation of 1-beta-D-arabinofuranosylcytosine 5'-triphosphate in human leukemic myeloblasts and lymphoblasts.
    Cancer research, 1987, Jun-15, Volume: 47, Issue:12

    Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cytarabine; DCMP Deaminase; Guanosine; Half-Life; Humans; Kinetics; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphocytes; Phosphorylation; Thioinosine; Thionucleosides

1987
Review of clinical and haematological response to low-dose cytosine arabinoside in acute myeloid leukaemia.
    European journal of haematology, 1987, Volume: 38, Issue:1

    Topics: Adult; Aged; Bone Marrow; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

1987
Side effects of intermediate- and high-dose cytosine arabinoside in the treatment of refractory or relapsed acute leukaemia and non-Hodgkin's lymphoma.
    The Netherlands journal of medicine, 1987, Volume: 30, Issue:1-2

    Topics: Adult; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Middle Aged

1987
[Termination rules in therapeutic trials. Application of sequential methods in 2 clinical trials in hematology].
    Nouvelle revue francaise d'hematologie, 1987, Volume: 29, Issue:1

    Topics: Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Random Allocation; Research Design

1987
Different response rates to low-dose cytosine arabinoside in acute myeloid leukemia subtypes.
    Seminars in oncology, 1987, Volume: 14, Issue:2 Suppl 1

    Topics: Age Factors; Antigens, Neoplasm; Antigens, Surface; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid, Acute; Prognosis

1987
Pharmacologic studies of low-dose and high-dose continuous infusion cytosine arabinoside.
    Seminars in oncology, 1987, Volume: 14, Issue:2 Suppl 1

    Topics: Adult; Aged; Arabinofuranosylcytosine Triphosphate; Arabinofuranosyluracil; Cytarabine; DNA Replication; Dose-Response Relationship, Drug; Female; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged; Replicon; Thrombocytopenia

1987
An in vitro model to predict clinical response in adult acute myelogenous leukemia.
    Seminars in oncology, 1987, Volume: 14, Issue:2 Suppl 1

    Topics: Adult; Arabinofuranosylcytosine Triphosphate; Blood; Bone Marrow; Cell Cycle; Cells, Cultured; Culture Media; Cytarabine; DNA, Neoplasm; Humans; In Vitro Techniques; Leukemia, Myeloid, Acute; Time Factors

1987
In vivo development of cytosine arabinoside resistance in the BN acute myelocytic leukemia.
    Seminars in oncology, 1987, Volume: 14, Issue:2 Suppl 1

    Topics: Animals; Cell Line; Cytarabine; Cytidine Deaminase; Deoxycytidine Kinase; Drug Resistance; Leukemia, Experimental; Leukemia, Myeloid, Acute; Nucleoside Deaminases; Rats

1987
Influence of dose and duration of exposure on the cytotoxic effect of cytarabine toward human hematopoietic clonogenic cells.
    Seminars in oncology, 1987, Volume: 14, Issue:2 Suppl 1

    Topics: Bone Marrow Cells; Cell Cycle; Cell Survival; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Neoplastic Stem Cells

1987
Prognostic value of in vitro uptake and retention of cytosine arabinoside in acute myelogenous leukemia.
    Seminars in oncology, 1987, Volume: 14, Issue:2 Suppl 1

    Topics: Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Daunorubicin; Humans; In Vitro Techniques; Leukemia, Myeloid, Acute; Prognosis

1987
Treatment of acute myeloid leukemia with intermediate-dose cytosine arabinoside and mitoxantrone.
    Seminars in oncology, 1987, Volume: 14, Issue:2 Suppl 1

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Time Factors

1987
Conventional dose cytosine arabinoside in combination chemotherapy for acute myelogenous leukemia.
    Seminars in oncology, 1987, Volume: 14, Issue:2 Suppl 1

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Doxorubicin; Humans; Leukemia, Myeloid, Acute; Middle Aged; Time Factors

1987
Continuous infusion high-dose cytosine arabinoside without anthracyclines as induction and intensification therapy in adults under age 50 with newly diagnosed acute myelogenous leukemia.
    Seminars in oncology, 1987, Volume: 14, Issue:2 Suppl 1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Prednisone; Time Factors; Translocation, Genetic; Vincristine

1987
High-dose cytosine arabinoside in combination with mitoxantrone for the treatment of refractory acute myeloid and lymphoblastic leukemia.
    Seminars in oncology, 1987, Volume: 14, Issue:2 Suppl 1

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Thioguanine

1987
The role of intensive remission induction and consolidation therapy in patients with acute myeloid leukaemia.
    British journal of haematology, 1987, Volume: 66, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Time Factors

1987
Intensive treatment of acute leukemia in adults 70 years of age and older.
    Cancer, 1987, Jul-15, Volume: 60, Issue:2

    Topics: Aged; Aged, 80 and over; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Doxorubicin; Drug Administration Schedule; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Prednisone; Remission Induction; Vincristine

1987
Prognostic factors in childhood acute myelogenous leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Daunorubicin; Doxorubicin; Humans; Leukemia, Myeloid, Acute; Leukocyte Count; Prednisolone; Remission Induction; Risk; Time Factors; Vincristine

1987
[Granulocytic sarcoma (chloroma) with bladder and breast localizations preceding acute myeloblastic leukemia].
    Revista clinica espanola, 1987, Volume: 180, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Cytarabine; Drug Combinations; Female; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Middle Aged; Neoplasms, Multiple Primary; Prednisone; Time Factors; Urinary Bladder Neoplasms; Vincristine

1987
C-reactive protein and cytosine arabinoside.
    British journal of haematology, 1987, Volume: 66, Issue:2

    Topics: C-Reactive Protein; Cytarabine; Drug Hypersensitivity; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

1987
Low dose cytosine arabinoside therapy in myelodysplastic syndrome and acute myeloid leukemia.
    Japanese journal of clinical oncology, 1987, Volume: 17, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Blood Cells; Bone Marrow; Cytarabine; Drug Evaluation; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Time Factors

1987
Anaphylactic shock due to cytarabine in a leukemic child.
    American journal of diseases of children (1960), 1987, Volume: 141, Issue:9

    Topics: Anaphylaxis; Child, Preschool; Cytarabine; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunoglobulin E; Leukemia, Myeloid, Acute

1987
The neurotoxicity of high-dose cytosine arabinoside is age-related.
    Cancer, 1987, Oct-01, Volume: 60, Issue:7

    Topics: Activities of Daily Living; Adolescent; Adult; Age Factors; Ataxia; Brain; Cerebellum; Coma; Confusion; Cytarabine; Dysarthria; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Sleep Stages

1987
Phase II study of amsacrine and high-dose cytarabine for resistant acute myelogenous leukemia.
    Cancer treatment reports, 1987, Volume: 71, Issue:9

    Topics: Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Evaluation; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

1987
Pharmacokinetics of daunorubicin as a determinant of response in acute myeloid leukemia.
    Haematology and blood transfusion, 1987, Volume: 30

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Kinetics; Leukemia, Myeloid, Acute; Vincristine

1987
Pharmacokinetic study of cytosine arabinoside in patients with acute myelogeneous leukemia.
    Haematology and blood transfusion, 1987, Volume: 30

    Topics: Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosyluracil; Cytarabine; Daunorubicin; Humans; Kinetics; Leukemia, Myeloid, Acute; Mitoxantrone; Thioguanine

1987
Low-dose cytosine arabinoside in patients with acute myeloblastic leukemia and myelodysplastic syndrome.
    Haematology and blood transfusion, 1987, Volume: 30

    Topics: Cytarabine; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Remission Induction; Time Factors

1987
Low-dose Ara-C treatment in elderly patients with acute myeloblastic leukemia.
    Haematology and blood transfusion, 1987, Volume: 30

    Topics: Aged; Blast Crisis; Cytarabine; Humans; Leukemia, Myeloid, Acute; Middle Aged

1987
Contribution of clonogenic leukemic cell characteristics to therapy outcome in patients with acute myeloblastic leukemia.
    Haematology and blood transfusion, 1987, Volume: 30

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colony-Forming Units Assay; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Remission Induction; Thioguanine; Tumor Stem Cell Assay

1987
4-Demethoxydaunorubicin (idarubicin) in relapsed and refractory acute myeloid leukemia.
    Haematology and blood transfusion, 1987, Volume: 30

    Topics: Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male

1987
Acute myelocytic leukemia in adults: a long-term analysis.
    Haematology and blood transfusion, 1987, Volume: 30

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Remission Induction; Time Factors

1987
High-dose cytosine arabinoside and retinol in the treatment of acute myelogenous leukemia in childhood.
    Haematology and blood transfusion, 1987, Volume: 30

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Diterpenes; Humans; Leukemia, Myeloid, Acute; Retinyl Esters; Vitamin A

1987
Effective remission induction in children with recurrent acute myeloid leukemia by mAMSA, Ara-C, and VP 16.
    Haematology and blood transfusion, 1987, Volume: 30

    Topics: Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Remission Induction; Time Factors

1987
Prediction of induction and duration of complete remission in acute myelogenous leukemia: value of clonogenic cell properties.
    Haematology and blood transfusion, 1987, Volume: 30

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colony-Forming Units Assay; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Prognosis; Remission Induction; Tumor Stem Cell Assay

1987
Postremission induction intensive sequential chemotherapy for children with AML--treatment results and prognostic factors.
    Haematology and blood transfusion, 1987, Volume: 30

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Daunorubicin; Doxorubicin; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Prednisolone; Prognosis; Remission Induction; Thioguanine; Time Factors; Vincristine

1987
Treatment of acute myelogenous leukemia in children: results of the Italian Cooperative Study AIEOP/LAM 8204.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:9

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Remission Induction; Thioguanine

1987
[Treatment of hypoplastic leukemia--clinical effects of low-dose 4N-behenoyl-beta-D-arabinofuranosylcytosine (BH-AC) therapy].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1987, Volume: 28, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Cytarabine; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction

1987
[Influences of aging on clinical pictures of hematological diseases: hypoplastic leukemia in the aged].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 1987, Volume: 24, Issue:2

    Topics: Aged; Aging; Antineoplastic Agents; Cytarabine; Humans; Leukemia, Myeloid, Acute

1987
Incomplete Reiter's syndrome following chemotherapy of acute myeloid leukaemia.
    Postgraduate medical journal, 1986, Volume: 62, Issue:733

    Topics: Adult; Allopurinol; Antineoplastic Combined Chemotherapy Protocols; Arthritis, Reactive; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Male; Thioguanine

1986
[Treatment of acute promyelocytic leukemia by retinoic acid with or without low dose cytosine arabinoside: report of 4 cases].
    Zhonghua nei ke za zhi, 1987, Volume: 26, Issue:6

    Topics: Cytarabine; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Tretinoin

1987
High risk of streptococcal septicemia after high dose cytosine arabinoside treatment for acute myelogenous leukemia.
    Klinische Wochenschrift, 1987, Aug-17, Volume: 65, Issue:16

    Topics: Adolescent; Adult; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myeloid, Acute; Male; Microbial Sensitivity Tests; Middle Aged; Remission Induction; Risk Factors; Sepsis; Streptococcal Infections; Streptococcus

1987
[Cytarabine].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:10

    Topics: Animals; Antineoplastic Agents; Cytarabine; Humans; Leukemia, Myeloid, Acute; Mice; Myelodysplastic Syndromes; Structure-Activity Relationship

1987
Prognostic value of clonogenic assay for induction and duration of complete remission in acute myelogenous leukemia.
    Leukemia, 1987, Volume: 1, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Colony-Forming Units Assay; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Time Factors; Tumor Cells, Cultured

1987
Mitoxantrone and ara-C in previously treated patients with acute myelogenous leukemia.
    Leukemia, 1987, Volume: 1, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Diarrhea; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Nausea; Vomiting

1987
Comparison between the plasma and intracellular pharmacology of 1-beta-D-arabinofuranosylcytosine and 9-beta-D-arabinofuranosyl-2-fluoroadenine 5'-monophosphate in patients with relapsed leukemia.
    Leukemia, 1987, Volume: 1, Issue:9

    Topics: Adult; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cytarabine; DNA Replication; Drug Evaluation; Female; Half-Life; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Vidarabine

1987
[High doses of cytosine arabinoside in the treatment of refractory leukemia].
    Sbornik lekarsky, 1987, Volume: 89, Issue:8-9

    Topics: Blast Crisis; Cytarabine; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute

1987
Neutrophilic eccrine hidradenitis in acute myelomonocytic leukemia.
    The American journal of pediatric hematology/oncology, 1987,Fall, Volume: 9, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Doxorubicin; Eccrine Glands; Female; Humans; Inflammation; Leukemia, Myeloid, Acute; Prednisolone; Remission Induction; Sweat Gland Diseases; Sweat Glands; Vincristine

1987
Remission of rheumatoid arthritis with the successful treatment of acute myelogenous leukemia with cytosine arabinoside, daunorubicin, and m-AMSA.
    Arthritis and rheumatism, 1987, Volume: 30, Issue:10

    Topics: Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Arthritis, Rheumatoid; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Middle Aged; Remission Induction

1987
Detection of 1-beta-D-arabinofuranosylcytosine incorporation into DNA in vivo.
    Cancer research, 1987, Dec-15, Volume: 47, Issue:24 Pt 1

    Topics: Adult; Aged; Cell Line; Chromatography, High Pressure Liquid; Cytarabine; DNA; Female; Humans; Hydrogen-Ion Concentration; Leukemia, Myeloid, Acute; Male; Middle Aged; Radioimmunoassay; Tumor Cells, Cultured

1987
Differentiation induction in myelodysplasia and acute myeloid leukaemia: use of synergistic drug combinations.
    Leukemia research, 1987, Volume: 11, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cell Differentiation; Cytarabine; Drug Synergism; Female; Humans; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Thioguanine; Tretinoin; Tumor Cells, Cultured; Vincristine

1987
Pattern of bone marrow regeneration following chemotherapy for acute myeloid leukemia.
    Journal of medicine, 1987, Volume: 18, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Daunorubicin; Etoposide; Humans; Leukemia, Myeloid, Acute; Regeneration; Thioguanine

1987
[Acute leukemia with blasts in the shape of a hand mirror].
    Terapevticheskii arkhiv, 1987, Volume: 59, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Histocytochemistry; Humans; Leukemia, Myeloid, Acute; Lymphocytes; Male; Middle Aged; Spiro Compounds; Vincristine

1987
Sensitivity of stromal elements from human bone marrow cells to cytosine arabinoside in vitro.
    Haematology and blood transfusion, 1987, Volume: 31

    Topics: Anemia, Aplastic; Bone Marrow; Cytarabine; Hematopoiesis; Humans; In Vitro Techniques; Leukemia, Myeloid, Acute

1987
[Therapy of patients with myeloid leukemia with small doses of cytosine arabinoside].
    Terapevticheskii arkhiv, 1987, Volume: 59, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Evaluation; Female; Humans; Injections, Intravenous; Injections, Subcutaneous; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction

1987
[Bone marrow changes in acute non-lymphocytic leukemia patients treated with low-dose Ara-C--implications of therapeutic mechanism].
    Gaoxiong yi xue ke xue za zhi = The Kaohsiung journal of medical sciences, 1987, Volume: 3, Issue:9

    Topics: Aged; Bone Marrow; Cell Differentiation; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction

1987
Few genetic mutations, many cancers, say experts.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1986, Jun-01, Volume: 134, Issue:11

    Topics: Acute Disease; Child; Cytarabine; Eye Neoplasms; Humans; Leukemia, Myeloid, Acute; Mutation; Neoplasms; Oncogenes; Retinoblastoma; T-Lymphocytes, Cytotoxic

1986
Pulmonary complications of cytosine-arabinoside therapy: radiographic findings.
    AJR. American journal of roentgenology, 1987, Volume: 149, Issue:1

    Topics: Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lung; Lymphoma, Non-Hodgkin; Prednisone; Radiography; Remission Induction; Respiratory Insufficiency

1987
Alteration of blast phenotype after low-dose cytarabine in children with acute myeloid leukemia.
    Haematology and blood transfusion, 1987, Volume: 30

    Topics: Antigens, Ly; Antigens, Surface; Bone Marrow; Child; Cytarabine; Humans; Leukemia, Myeloid, Acute; Phenotype; T-Lymphocytes

1987
Lack of cross-resistance between cytosine arabinoside and a new halogenated nucleoside analogue, 2-bromo-2'-deoxyadenosine in human acute myeloid leukaemia cells.
    Cancer chemotherapy and pharmacology, 1987, Volume: 20, Issue:2

    Topics: Cell Line; Cytarabine; Cytidine Deaminase; Demecolcine; Deoxyadenosines; Deoxycytidine Kinase; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance; Flow Cytometry; Humans; Leukemia, Myeloid, Acute; Tumor Cells, Cultured; Tumor Stem Cell Assay

1987
Treatment of poor prognosis acute myeloid leukemia with aggressive and non-aggressive chemotherapy.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1987, Volume: 6, Issue:2 Suppl

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Prognosis

1987
TAD-induction therapy for 175 adults with acute myeloid leukemia, followed by consolidation and maintenance therapy. The joint study of Ulm and Tübingen.
    Onkologie, 1986, Volume: 9, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Combinations; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Prednisolone; Prednisone; Thioguanine; Vincristine

1986
Age adapted induction and intensified consolidation therapy in acute myelogenous leukemia.
    Onkologie, 1986, Volume: 9, Issue:3

    Topics: Aclarubicin; Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Naphthacenes; Prognosis

1986
High-dose cytosine-arabinoside and mitoxantrone in refractory acute myeloid leukemia: a clinical phase I/II-study.
    Onkologie, 1986, Volume: 9, Issue:3

    Topics: Anthraquinones; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Drug Evaluation; Drug Resistance; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Prognosis

1986
Idarubicin in refractory acute leukemia.
    Onkologie, 1986, Volume: 9, Issue:3

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Resistance; Etoposide; Female; Follow-Up Studies; Humans; Idarubicin; Infusions, Parenteral; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged

1986
Aclacinomycin-A in the induction treatment of childhood AML.
    Onkologie, 1986, Volume: 9, Issue:3

    Topics: Aclarubicin; Adolescent; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Etoposide; Female; Follow-Up Studies; Humans; Infant; Infusions, Parenteral; Leukemia, Myeloid, Acute; Male; Naphthacenes; Thioguanine

1986
[Therapy of acute leukemia in the adult. Role of anthracyclines].
    Pathologie-biologie, 1987, Volume: 35, Issue:1

    Topics: Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Doxorubicin; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute

1987
[Therapeutic trials of aclarubicin in previously treated acute leukemias and hematosarcomas].
    Pathologie-biologie, 1987, Volume: 35, Issue:1

    Topics: Aclarubicin; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Child; Child, Preschool; Cytarabine; Drug Evaluation; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Middle Aged; Naphthacenes

1987
Ara-C incorporation into DNA.
    Blood, 1985, Volume: 65, Issue:1

    Topics: Cytarabine; DNA; Humans; Leukemia, Myeloid, Acute

1985
Acute promyelocytic leukemia in 57 previously untreated patients.
    Cancer, 1985, Jan-01, Volume: 55, Issue:1

    Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Transfusion; Cytarabine; Daunorubicin; Disseminated Intravascular Coagulation; Female; Heparin; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Platelet Transfusion; Prognosis; Respiratory Insufficiency; Time Factors

1985
Treatment of ocular leukemia with local chemotherapy.
    Cancer treatment reports, 1985, Volume: 69, Issue:1

    Topics: Adrenal Cortex Hormones; Adult; Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Conjunctiva; Cytarabine; Eye Neoplasms; Female; Humans; Injections; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate

1985
Intermediate and high-dose ARA-C and m-AMSA (or daunorubicin) as remission and consolidation treatment for patients with relapsed acute leukaemia and lymphoblastic non-Hodgkin lymphoma.
    Scandinavian journal of haematology, 1985, Volume: 34, Issue:1

    Topics: Adolescent; Adult; Aminoacridines; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Fever; Humans; Intercalating Agents; Intestinal Obstruction; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Middle Aged; Nausea; Time Factors; Vomiting

1985
Differences in cell cycle kinetics during induced granulocytic versus monocytic maturation of HL-60 leukemia cells.
    Cancer research, 1985, Volume: 45, Issue:3

    Topics: Cell Count; Cell Cycle; Cell Line; Cytarabine; Dimethyl Sulfoxide; DNA, Neoplasm; Granulocytes; Humans; Leukemia, Myeloid, Acute; Monocytes; Neoplasm Proteins

1985
Adriamycin and cytosine arabinoside contribute equally to prediction of response in acute myelocytic leukemia with improved confidence level.
    Cancer chemotherapy and pharmacology, 1985, Volume: 14, Issue:2

    Topics: Cytarabine; Dose-Response Relationship, Drug; Doxorubicin; Drug Interactions; Interphase; Leukemia, Myeloid, Acute; Time Factors; Tumor Stem Cell Assay

1985
[The effect of cytostatic therapy on pyruvate kinase activity in the erythrocytes of patients with acute myelocytic leukemia].
    Lijecnicki vjesnik, 1985, Volume: 107, Issue:2

    Topics: Adenosine Triphosphate; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Doxorubicin; Erythrocytes; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Pyruvate Kinase

1985
Cytokinetic studies in acute leukemia during early induction therapy.
    Tumori, 1985, Feb-28, Volume: 71, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cell Division; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Peptichemio; Prednisone; Time Factors; Vincristine

1985
[Various induction therapies in older patients with acute myeloid leukemias].
    Wiener klinische Wochenschrift, 1985, Feb-01, Volume: 97, Issue:3

    Topics: Aclarubicin; Adolescent; Adult; Aged; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Danazol; Dose-Response Relationship, Drug; Etoposide; Female; Humans; Leukapheresis; Leukemia, Myeloid, Acute; Male; Middle Aged; Naphthacenes; Tamoxifen

1985
Prediction of response of acute non-lymphocytic leukaemia to therapy with 'high dose' cytosine arabinoside.
    British journal of haematology, 1985, Volume: 59, Issue:4

    Topics: Adult; Aged; Bone Marrow; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

1985
[Treatment of acute myeloid leukemia with amsacrine and high-dose cytosine arabinoside: a phase II trial].
    Bulletin du cancer, 1985, Volume: 72, Issue:1

    Topics: Adult; Aminoacridines; Amsacrine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Evaluation; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

1985
[ACMP two-step therapy for children with acute nonlymphoblastic leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1985, Volume: 26, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Doxorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Prednisolone

1985
Myxoedema in a case of acute myeloid leukaemia.
    Scandinavian journal of haematology, 1985, Volume: 34, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Myxedema; Thioguanine; Thyroxine

1985
Effects of pyrimidine antagonists on sialic acid regeneration in HL-60 cells.
    Cancer research, 1985, Volume: 45, Issue:7

    Topics: 3-Deazauridine; Agglutination; Antimetabolites, Antineoplastic; Cell Line; Cytarabine; Cytidine Triphosphate; Doxorubicin; Glucosamine; Humans; Isoxazoles; Lectins; Leukemia, Myeloid, Acute; N-Acetylneuraminic Acid; Pyrimidines; Sialic Acids

1985
Changes in the characteristics of the bone marrow during therapy for acute non-lymphocytic leukemia: relationship to response to remission induction therapy.
    European journal of cancer & clinical oncology, 1985, Volume: 21, Issue:5

    Topics: Aged; Bone Marrow; Cytarabine; DNA, Neoplasm; Humans; Interphase; Leukemia, Myeloid, Acute; Middle Aged; Prognosis; Time Factors

1985
Pharmacokinetics and cellular determinants of response to 1-beta-arabinofuranosylcytosine (ara-C).
    Seminars in oncology, 1985, Volume: 12, Issue:2 Suppl 3

    Topics: Animals; Arabinofuranosylcytosine Triphosphate; Bone Marrow; Cytarabine; Dose-Response Relationship, Drug; Drug Resistance; Humans; Leukemia; Leukemia L1210; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mice; Mice, Inbred DBA

1985
Intensive timed chemotherapy for 51 acute myeloid leukemia patients with poor prognosis.
    Seminars in oncology, 1985, Volume: 12, Issue:2 Suppl 3

    Topics: Adult; Aged; Cytarabine; Drug Resistance; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Recurrence; Time Factors

1985
High-dose cytosine arabinoside in the initial treatment of acute leukemia.
    Seminars in oncology, 1985, Volume: 12, Issue:2 Suppl 3

    Topics: Adolescent; Adult; Bone Marrow; Cytarabine; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence

1985
Modulation of cytosine arabinoside (ara-C) and high-dose ara-C in acute leukemia.
    Seminars in oncology, 1985, Volume: 12, Issue:2 Suppl 3

    Topics: Aminoacridines; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Resistance; Humans; Hydroxyurea; Interphase; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Thymidine

1985
High-dose cytosine arabinoside in the treatment of childhood malignancies.
    Seminars in oncology, 1985, Volume: 12, Issue:2 Suppl 3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Diseases; Child; Child, Preschool; Cytarabine; Diterpenes; Doxorubicin; Female; Humans; Infant; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma; Male; Pancytopenia; Recurrence; Retinyl Esters; Vitamin A; Vomiting

1985
In vivo studies on high-dose 1-beta-D-arabinofuranosylcytosine (HDara-C) and 1-beta-D-arabinofuranosyluracil (ara-U) with respect to pharmacokinetics, cell kinetics, and cytotoxicity in a rat myelocytic leukemia model (BNML).
    Seminars in oncology, 1985, Volume: 12, Issue:2 Suppl 3

    Topics: Animals; Arabinofuranosyluracil; Cell Cycle; Colony-Forming Units Assay; Cytarabine; Cytidine Deaminase; Disease Models, Animal; Half-Life; Humans; Kinetics; Leukemia, Myeloid, Acute; Nucleoside Deaminases; Rats; Uridine

1985
Increased tumor growth and drug uptake predicts for response to continuous infusion high-dose cytarabine.
    Seminars in oncology, 1985, Volume: 12, Issue:2 Suppl 3

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cell Division; Cytarabine; Daunorubicin; DNA; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid, Acute; Middle Aged

1985
Evolution of clinical studies with high-dose cytosine arabinoside at the M.D. Anderson Hospital.
    Seminars in oncology, 1985, Volume: 12, Issue:2 Suppl 3

    Topics: Arabinofuranosylcytosine Triphosphate; Chromosome Aberrations; Cytarabine; Drug Evaluation; Drug Resistance; Half-Life; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Prognosis; Time Factors

1985
Low-dose cytosine arabinoside regimen induced a complete remission with normal karyotypes in a case with hypoplastic acute myeloid leukaemia with No. 8-trisomy: in vitro and in vivo evidence for normal haematopoietic recovery.
    British journal of haematology, 1985, Volume: 60, Issue:3

    Topics: Chromosomes, Human, 6-12 and X; Colony-Forming Units Assay; Cytarabine; Female; Hematopoiesis; Humans; Infusions, Parenteral; Karyotyping; Leukemia, Myeloid, Acute; Middle Aged; Time Factors; Trisomy

1985
Low-dose cytosine arabinoside in the myelodysplastic syndromes and acute myelogenous leukemia.
    Cancer, 1985, Sep-01, Volume: 56, Issue:5

    Topics: Adult; Aged; Bone Marrow; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Leukopenia; Male; Myeloproliferative Disorders; Thrombocytopenia

1985
[Small doses of Ara-C in the treatment of acute myeloid leukaemia].
    Zhonghua nei ke za zhi, 1985, Volume: 24, Issue:6

    Topics: Adolescent; Adult; Cytarabine; Female; Humans; Injections, Subcutaneous; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged

1985
[Treatment of acute myelogenous leukemia with concurrent administration of N4-behenoyl-ara-C, aclacinomycin A, 6-mercaptopurine and prednisolone].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1985, Volume: 26, Issue:2

    Topics: Aclarubicin; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Naphthacenes; Prednisolone

1985
[Use of cytosar (cytosine arabinoside) in the control of herpetic complications in patients with acute leukemia and lymphogranulomatosis].
    Terapevticheskii arkhiv, 1985, Volume: 57, Issue:5

    Topics: Adolescent; Aged; Chickenpox; Child, Preschool; Cytarabine; Female; Herpes Zoster; Hodgkin Disease; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male

1985
Treatment of acute myelogenous leukemia in adults with N4-behenoyl-1-beta-D-arabinofuranosylcytosine.
    Cancer, 1985, Oct-15, Volume: 56, Issue:8

    Topics: Adolescent; Adult; Aged; Anorexia; Antineoplastic Agents; Cytarabine; Diarrhea; Drug Evaluation; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Nausea; Skin Diseases

1985
Treatment of acute myeloid leukemia and myelodysplastic syndrome by low dose cytosine arabinoside.
    Haematology and blood transfusion, 1985, Volume: 29

    Topics: Aged; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Myeloproliferative Disorders

1985
[A trial administration of small doses of Ara-C as a second step in remission induction in patients with acute non-lymphocytic leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1985, Volume: 26, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Humans; Leukemia, Myeloid, Acute; Male

1985
[Cytosine-arabinoside in high doses in refractory acute granulocytic leukemia. Apropos of 17 cases].
    Nouvelle revue francaise d'hematologie, 1985, Volume: 27, Issue:3

    Topics: Adolescent; Adult; Cytarabine; Drug Resistance; Eye Diseases; Female; Hematologic Diseases; Humans; Leukemia, Myeloid, Acute; Leukopenia; Male; Middle Aged

1985
Acute granulocytic leukemia following systemic lupus erythematosus.
    The American journal of the medical sciences, 1985, Volume: 290, Issue:1

    Topics: Adrenal Cortex Hormones; Adult; Aged; Aspirin; Cyclophosphamide; Cytarabine; Humans; Immunosuppression Therapy; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lupus Erythematosus, Systemic; Male

1985
[Leukocytosis induced by BH-AC administration--allergic reaction to Casteo oil HCO-60. A case report].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1985, Volume: 26, Issue:4

    Topics: Adolescent; Antineoplastic Agents; Castor Oil; Cytarabine; Drug Hypersensitivity; Female; Humans; Leukemia, Myeloid, Acute; Leukocytosis; Solvents

1985
Effects of chemotherapy on bone marrow stroma in mice with acute myelogenous leukemia. Correlation with CFU-C and CFU-D.
    Leukemia research, 1985, Volume: 9, Issue:8

    Topics: Animals; Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Cytarabine; Diffusion; Doxorubicin; Fibroblasts; Granulocytes; Hematopoietic Stem Cells; Hydroxyurea; Leukemia, Experimental; Leukemia, Myeloid, Acute; Macrophages; Male; Mice; Mice, Inbred C57BL; Time Factors

1985
Plasma fibronectin in acute myeloid leukaemia.
    Scandinavian journal of haematology, 1985, Volume: 35, Issue:2

    Topics: Adult; Aged; Blood Transfusion; Cytarabine; Daunorubicin; Female; Fibronectins; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Precipitin Tests; Thioguanine

1985
Treatment of acute myelogenous leukemia in children.
    Medical oncology and tumor pharmacotherapy, 1985, Volume: 2, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Doxorubicin; Humans; Leukemia, Myeloid, Acute; Methotrexate; Prednisolone; Prednisone; Risk; Thioguanine; Vincristine

1985
Effects of cytosine arabinoside on DNA synthesis and mitotic activity of HL-60 cells.
    Medical oncology and tumor pharmacotherapy, 1985, Volume: 2, Issue:1

    Topics: Autoradiography; Cell Count; Cell Line; Cytarabine; Demecolcine; DNA Replication; Humans; Interphase; Leukemia, Myeloid, Acute; Mitosis; Thymidine; Time Factors

1985
[Acute myelomonocytic and monoblastic leukemia with polyradicular symptoms].
    Wiener klinische Wochenschrift, 1985, Aug-30, Volume: 97, Issue:16

    Topics: Abducens Nerve; Adult; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cerebral Hemorrhage; Cerebrospinal Fluid; Cranial Nerve Diseases; Cytarabine; Danazol; Demyelinating Diseases; Facial Paralysis; Female; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Meningism; Methotrexate; Middle Aged; Spinal Nerve Roots; Tamoxifen

1985
[Sequential combination of high-dose cytosine arabinoside and L-asparaginase in the treatment of refractory acute leukemia and malignant lymphoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:11

    Topics: Adult; Asparaginase; Cytarabine; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma; Male; Middle Aged

1985
Pharmacokinetics of low-dose 1-beta-D-arabinofuranosylcytosine given by continuous intravenous infusion over twenty-one days.
    Cancer research, 1985, Volume: 45, Issue:12 Pt 1

    Topics: Aged; Cytarabine; Female; Humans; Injections, Intravenous; Kinetics; Leukemia, Myeloid, Acute; Male; Middle Aged; Preleukemia

1985
Treatment of acute myeloid leukemia developing after a myelodysplastic phase with low dose arabinosyl cytosine.
    Leukemia research, 1985, Volume: 9, Issue:10

    Topics: Aged; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes

1985
Effects of 13-cis retinoic acid and Ara-C on differentiation and proliferation of non-promyelocytic acute myelogenous leukemia.
    Leukemia research, 1985, Volume: 9, Issue:11

    Topics: Adult; Aged; Alkaline Phosphatase; Cell Differentiation; Cell Division; Cytarabine; Female; Humans; Isotretinoin; Leukemia, Myeloid, Acute; Leukocytes; Male; Middle Aged; Thymidine; Tretinoin; Tritium

1985
The cytarabine syndrome in adults.
    Australian and New Zealand journal of medicine, 1985, Volume: 15, Issue:4

    Topics: Adolescent; Adult; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Syndrome

1985
[Chemosensitivity assay in acute leukemia].
    Zhonghua nei ke za zhi, 1985, Volume: 24, Issue:9

    Topics: Colony-Forming Units Assay; Cytarabine; Harringtonines; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Tumor Stem Cell Assay

1985
Comparison of autoradiography and DNA histograms in assessing S-phase cells from patients with myeloid leukemias.
    Medical oncology and tumor pharmacotherapy, 1985, Volume: 2, Issue:4

    Topics: Animals; Autoradiography; Bone Marrow; Cells, Cultured; Cytarabine; DNA Replication; DNA, Neoplasm; Doxorubicin; Flow Cytometry; Humans; Interphase; Leukemia; Leukemia P388; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphocytes; Mice

1985
Treatment of chronic myelogenous leukemia in blastic crisis with chemotherapy incorporating vindesine-prednisolone.
    Cancer treatment reports, 1985, Volume: 69, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisolone; Vindesine

1985
[Treatment of malignant hemopathies with aracytine in low doses. Analysis of 159 cases].
    Nouvelle revue francaise d'hematologie, 1985, Volume: 27, Issue:6

    Topics: Aged; Aging; Cytarabine; Humans; Leukemia, Myeloid, Acute; Middle Aged; Myeloproliferative Disorders; Retrospective Studies

1985
[The response of cells to anti-tumour drugs estimated by limiting dilution in microwell culture].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1985, Volume: 20, Issue:6

    Topics: Antineoplastic Agents; Cell Line; Colony-Forming Units Assay; Cytarabine; Dose-Response Relationship, Drug; Doxorubicin; Humans; Leukemia, Myeloid, Acute; Thioguanine; Tumor Stem Cell Assay

1985
Cytosine arabinoside transport and metabolism in acute leukemias and T cell lymphoblastic lymphoma.
    The Journal of clinical investigation, 1985, Volume: 75, Issue:2

    Topics: Adolescent; Adult; Aged; Arabinofuranosylcytosine Triphosphate; Biological Transport, Active; Biotransformation; Child; Child, Preschool; Cytarabine; Humans; In Vitro Techniques; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Middle Aged; T-Lymphocytes

1985
Cytosine-arabinoside-induced colitis and peritonitis: nonoperative management.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1985, Volume: 3, Issue:5

    Topics: Abdomen; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colitis; Cryptococcosis; Cytarabine; Female; Gastrointestinal Hemorrhage; Humans; Leukemia, Myeloid, Acute; Male; Nausea; Pain; Pancytopenia; Peritonitis; Radiography

1985
Response to hydrocortisone of blast progenitors in acute myeloblastic leukemia: an aspect of lineage infidelity.
    Leukemia research, 1985, Volume: 9, Issue:12

    Topics: Adolescent; Adult; Aged; Cell Differentiation; Cytarabine; Dose-Response Relationship, Drug; Hematopoietic Stem Cells; Humans; Hydrocortisone; Leukemia, Myeloid, Acute; Middle Aged; Phenotype; T-Lymphocytes

1985
[High-dose cytarabine treatment: a promising therapy modality in acute resistant myeloid leukemias in recurrence].
    Onkologie, 1985, Volume: 8, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Drug Resistance; Female; Humans; Leukemia, Myeloid, Acute; Male; Meningeal Neoplasms; Middle Aged

1985
[High-dose cytarabine treatment in acute leukemias and leukemic meningiosis: clinical aspects and pharmacokinetics].
    Onkologie, 1985, Volume: 8, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Kinetics; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Meningeal Neoplasms; Middle Aged

1985
[Experiences with HD-Ara C treatment in leukemia patients].
    Onkologie, 1985, Volume: 8, Issue:1

    Topics: Acute Disease; Aminoacridines; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia; Leukemia, Myeloid, Acute

1985
[High-dose cytosine arabinoside in the treatment of recurrent or acute refractory myeloid leukemias].
    Onkologie, 1985, Volume: 8, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

1985
[Therapeutic experiences with high-dose ARA-C and L-ASP].
    Onkologie, 1985, Volume: 8, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Brain Neoplasms; Child, Preschool; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Testicular Neoplasms

1985
[Results of therapy with high-dose cytosine arabinoside].
    Onkologie, 1985, Volume: 8, Issue:1

    Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged

1985
[High-dose cytarabine treatment with asparaginase (Capizzi schedule) in recurrent or refractory AML in the adult].
    Onkologie, 1985, Volume: 8, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

1985
[Results of high-dose cytarabine therapy. A review].
    Onkologie, 1985, Volume: 8, Issue:1

    Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma

1985
Remission from central nervous system involvement in adults with acute leukemia. Effect of intensive therapy and prognostic factors.
    Cancer, 1985, Aug-01, Volume: 56, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Humans; Hydrocortisone; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Meningeal Neoplasms; Methotrexate; Prognosis; Radiotherapy Dosage

1985
The combined use of cytosine arabinoside, cyclophosphamide, and total body irradiation as preparative regimen for bone marrow transplantation in patients with AML and CML.
    Seminars in oncology, 1985, Volume: 12, Issue:2 Suppl 3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Graft vs Host Disease; Humans; Infections; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Pulmonary Fibrosis; Whole-Body Irradiation

1985
High-dose cytarabine in consolidation chemotherapy or with bone marrow transplantation for patients with acute leukemia: preliminary results.
    Seminars in oncology, 1985, Volume: 12, Issue:2 Suppl 3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Female; Graft vs Host Disease; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Pulmonary Fibrosis; Recurrence; T-Lymphocytes; Thioguanine; Whole-Body Irradiation

1985
[Thrombocyte replacement in hematologic diseases].
    Wiener klinische Wochenschrift, 1985, Nov-22, Volume: 97, Issue:22

    Topics: Acute Disease; Adolescent; Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Blood Platelets; Blood Transfusion; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Daunorubicin; Disseminated Intravascular Coagulation; Doxorubicin; Fever; Hematologic Diseases; Hemorrhage; Histocompatibility; HLA Antigens; Humans; Leukemia; Leukemia, Myeloid, Acute; Middle Aged; Plateletpheresis

1985
Synergistic interaction between differentiation inducers and DNA synthesis inhibitors: a new approach to differentiation induction in myelodysplasia and acute myeloid leukaemia.
    Leukemia research, 1985, Volume: 9, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Aphidicolin; Bone Marrow; Bone Marrow Diseases; Cell Differentiation; Cells, Cultured; Cytarabine; Diterpenes; DNA; Drug Synergism; Formamides; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Preleukemia; Syndrome; Tretinoin

1985
Effect of antimetabolites and thymidine blockage on the induction of differentiation of HL-60 cells by retinoic acid or 1 alpha,25-dihydroxyvitamin D3.
    Experimental hematology, 1985, Volume: 13, Issue:10

    Topics: Antibiotics, Antineoplastic; Aphidicolin; Calcitriol; Cell Differentiation; Cell Division; Cell Line; Cytarabine; Diterpenes; DNA Replication; Humans; Hydroxyurea; Kinetics; Leukemia, Myeloid, Acute; Tretinoin

1985
[HOAP/HOAGP in the treatment of acute non-lymphocytic leukemia: an analysis of 68 cases].
    Zhonghua yi xue za zhi, 1985, Volume: 65, Issue:10

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Female; Harringtonines; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisone; Thioguanine; Vincristine

1985
Serum vitamin B12-binding capacity and muramidase changes with cyclic neutropenia induced by cytosine arabinoside.
    Blood, 1971, Volume: 37, Issue:1

    Topics: Adult; Agranulocytosis; Alpha-Globulins; Beta-Globulins; Blood Cell Count; Blood Protein Electrophoresis; Bone Marrow Examination; Cobalt Isotopes; Cytarabine; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Muramidase; Periodicity; Protein Binding; Vitamin B 12

1971
Cytosine arabinoside and herpes zoster.
    Lancet (London, England), 1971, Jul-17, Volume: 2, Issue:7716

    Topics: Acute Disease; Adolescent; Adult; Child, Preschool; Cytarabine; Herpes Zoster; Herpesvirus 3, Human; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Remission, Spontaneous; Time Factors

1971
Cytosine arabinoside in the treatment of acute myeloblastic leukaemia.
    Lancet (London, England), 1971, Jun-19, Volume: 1, Issue:7712

    Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Age Factors; Aged; Amino Sugars; Antibiotics, Antineoplastic; Antineoplastic Agents; Cytarabine; Drug Synergism; Female; Follow-Up Studies; Glycosides; Humans; Injections, Intravenous; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisolone; Pregnancy; Remission, Spontaneous; Time Factors

1971
Philadelphia-chromosome-positive preleukaemic state.
    Lancet (London, England), 1972, Dec-09, Volume: 2, Issue:7789

    Topics: Adult; Blood Cell Count; Bone Marrow Cells; Bone Marrow Examination; Chromosome Aberrations; Cytarabine; Cytogenetics; Daunorubicin; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Male; Prednisone; Thioguanine; Vincristine

1972
Sideroblastic anemia in multiple myeloma: a preleukemic change.
    Blood, 1973, Volume: 41, Issue:1

    Topics: Anemia, Sideroblastic; Bone Marrow Examination; Cytarabine; Female; Humans; Immunodiffusion; Immunoelectrophoresis; Immunoglobulins; Iron; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Melphalan; Mercaptopurine; Middle Aged; Multiple Myeloma; Muramidase; Precancerous Conditions; Prednisone; Staining and Labeling; Vincristine

1973
Fatal outcome after combined therapy for myeloblastic leukaemia and toxoplasmosis.
    Lancet (London, England), 1973, Mar-31, Volume: 1, Issue:7805

    Topics: Autopsy; Bone Marrow; Bone Marrow Cells; Cytarabine; Daunorubicin; Humans; Leucovorin; Leukemia, Myeloid, Acute; Pyrimethamine; Toxoplasmosis

1973
Fatal outcome after combined therapy for myeloblastic leukaemia and toxoplasmosis.
    Lancet (London, England), 1973, Mar-17, Volume: 1, Issue:7803

    Topics: Aged; Antineoplastic Agents; Bone Marrow Diseases; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Male; Pyrimethamine; Sulfamethazine; Toxoplasmosis

1973
Acute leukaemia in myeloma.
    Lancet (London, England), 1973, Sep-08, Volume: 2, Issue:7828

    Topics: Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Melphalan; Mercaptopurine; Middle Aged; Multiple Myeloma

1973
Editorial: Immunotherapy for acute myeloid leukaemia.
    Lancet (London, England), 1974, May-04, Volume: 1, Issue:7862

    Topics: Antibodies, Neoplasm; Antibody Formation; Antigen-Antibody Complex; Antigens, Neoplasm; BCG Vaccine; Cell Transformation, Neoplastic; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Immunologic Deficiency Syndromes; Immunotherapy; Leukemia, Myeloid, Acute; Remission, Spontaneous; Thioguanine

1974
[Antimetabolites in the treatment of acute human leukoses. Mechanism of action and conditioning factors in the cellular response to drugs. II].
    La Clinica terapeutica, 1974, Apr-30, Volume: 69, Issue:2

    Topics: Antimetabolites; Azacitidine; Azaguanine; Azauridine; Cell Membrane Permeability; Cytarabine; DNA, Neoplasm; Fluorouracil; Humans; Immunity, Cellular; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Purines; Pyrimidines

1974
Letter: Adriamycin in acute leukaemia.
    Lancet (London, England), 1974, Jul-20, Volume: 2, Issue:7873

    Topics: Adolescent; Adult; Child; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Drug Therapy, Combination; Humans; Infusions, Parenteral; Injections, Intravenous; Leukemia, Myeloid, Acute; Middle Aged; Remission, Spontaneous

1974
Chemoimmunotherapy of adult acute leukaemia. Prolongation of remission in myeloblastic leukaemia with B.C.G.
    Lancet (London, England), 1974, Dec-14, Volume: 2, Issue:7894

    Topics: Administration, Oral; Adult; Antibody Formation; BCG Vaccine; Bone Marrow; Bone Marrow Cells; Cytarabine; Drug Therapy, Combination; Humans; Hypersensitivity, Delayed; Immunotherapy; In Vitro Techniques; Injections, Intravenous; Leukemia, Myeloid, Acute; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Middle Aged; Prednisone; Remission, Spontaneous; Skin Tests; Time Factors; Vincristine

1974
[1973 treatment of acute leukemias].
    Minerva medica, 1974, Dec-15, Volume: 65, Issue:90

    Topics: Chlorambucil; Colchicine; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Humans; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Vinblastine; Vincristine

1974
Adult acute leukaemia.
    British journal of cancer, 1974, Volume: 30, Issue:3

    Topics: Acute Disease; Administration, Oral; Adult; Aged; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Cytosine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Humans; Injections, Intravenous; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Middle Aged; Prednisone; Remission, Spontaneous; Staining and Labeling; Thioguanine; Vincristine

1974
Allogeneic marrow grafts in man using cyclophosphamide.
    Transplantation proceedings, 1974, Volume: 6, Issue:4

    Topics: Amidines; Bone Marrow; Bone Marrow Cells; Bone Marrow Transplantation; Cyclophosphamide; Cytarabine; Cytomegalovirus; Graft vs Host Disease; Graft vs Host Reaction; Herpesviridae; Histocompatibility Testing; Humans; Immunologic Deficiency Syndromes; Injections, Spinal; Karyotyping; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukocyte Count; Lymphocyte Culture Test, Mixed; Methotrexate; Phenyl Ethers; Pneumonia; Prednisone; Transplantation Immunology; Transplantation, Homologous

1974
Varicella and cytosine arabinoside.
    Lancet (London, England), 1970, Feb-07, Volume: 1, Issue:7641

    Topics: Chickenpox; Child; Child, Preschool; Cytarabine; Female; Herpesvirus 3, Human; Humans; Leukemia, Myeloid, Acute; Male

1970
[Activity of methionine synthetase (5-methyl-5,6,7,8-tetrahydrofolate: homocysteine methyltransferase) as a proliferation parameter in growing cells].
    Acta haematologica, 1973, Volume: 49, Issue:4

    Topics: Cell Division; Cells, Cultured; Cytarabine; DNA Nucleotidyltransferases; Folic Acid; Humans; In Vitro Techniques; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Methionine; Methyltransferases; Prednisolone; Tetrahydrofolates; Thioguanine; Thymidine Kinase; Vincristine

1973
[Therapy of acute leukosis with cytarabine].
    Haematologica, 1973, Volume: 58, Issue:3

    Topics: Cyclophosphamide; Cytarabine; Humans; Leukemia, Myeloid, Acute; Remission, Spontaneous

1973
Acute myelomonocytic leukemia in a patient with Hodgkin's disease.
    Acta haematologica, 1973, Volume: 49, Issue:5

    Topics: Adult; Bone Marrow Examination; Cobalt Isotopes; Cytarabine; Female; Hodgkin Disease; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Lymph Nodes; Radiation Injuries

1973
Human leukemia antigens: partial isolation and characterization.
    Journal of the National Cancer Institute, 1974, Volume: 52, Issue:5

    Topics: Animals; Antigens, Neoplasm; Cell Line; Cell Membrane; Centrifugation; Chromatography, Gel; Cycloheximide; Cytarabine; Cytotoxicity Tests, Immunologic; Dactinomycin; Haplorhini; Histocompatibility Antigens; Humans; Immune Sera; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Lymphocytes; Microscopy, Electron; Neuraminidase; Papain; Potassium Chloride; Pronase; Puromycin; Rabbits; Subcellular Fractions; Temperature; Trypsin

1974
Pseudo-Chediak-Higashi anomaly in acute leukemia. A significant morphologic corollary?
    American journal of clinical pathology, 1974, Volume: 62, Issue:5

    Topics: Adult; Aged; Blood Transfusion; Carbenicillin; Cephalothin; Chediak-Higashi Syndrome; Cyclophosphamide; Cytarabine; Escherichia coli; Female; Gentamicins; Hepatitis B; Humans; Klebsiella; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukoencephalopathy, Progressive Multifocal; Lung Abscess; Male; Prednisone; Pseudomonas aeruginosa; Sepsis; Urinary Tract Infections; Vincristine

1974
The effect of autologous serum on lymphocyte response to human leukemia cells.
    Blood, 1974, Volume: 43, Issue:6

    Topics: Adolescent; Adult; Asparaginase; Child; Child, Preschool; Cytarabine; Female; Humans; Immune Sera; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocytes; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Lymphocytes; Male; Mercaptopurine; Methotrexate; Middle Aged; Nitrosourea Compounds; Prednisolone; Prognosis; Thioguanine; Vincristine

1974
Acute leukemias and Burkitt's lymphoma. Present status of therapy.
    Cancer, 1968, Volume: 21, Issue:4

    Topics: Antineoplastic Agents; Asparaginase; Burkitt Lymphoma; Choriocarcinoma; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Female; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Melphalan; Mercaptopurine; Methotrexate; Prednisone; Pregnancy; Vincristine; Wilms Tumor

1968
Cytocentrifugation in the management of central nervous system leukemia.
    The Journal of pediatrics, 1972, Volume: 81, Issue:5

    Topics: Arachnoiditis; Central Nervous System Diseases; Centrifugation; Cytarabine; Humans; Hydrocortisone; Injections, Spinal; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate; Neoplasms, Nerve Tissue

1972
Septicaemia due to Pasteurella pneumotropica.
    Journal of clinical pathology, 1973, Volume: 26, Issue:6

    Topics: Ampicillin; Cephaloridine; Chloramphenicol; Culture Media; Cytarabine; Daunorubicin; Erythromycin; Gentamicins; Humans; Kanamycin; Leukemia, Myeloid, Acute; Male; Microbial Sensitivity Tests; Middle Aged; Pasteurella Infections; Polymyxins; Sepsis; Tetracycline

1973
Letter: Androgen role in erythroleukemia after treatment with alkylating agents.
    Annals of internal medicine, 1974, Volume: 81, Issue:1

    Topics: Adult; Alkylating Agents; Androgens; Carcinoma, Intraductal, Noninfiltrating; Chlorambucil; Cytarabine; Female; Fluoxymesterone; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lung Neoplasms; Neoplasm Metastasis; Thiotepa

1974
Mechanisms of resistance of human acute leukaemia cells to cytosine arabinoside.
    British journal of haematology, 1974, Volume: 27, Issue:1

    Topics: Adult; Aminohydrolases; Bone Marrow; Bone Marrow Cells; Cytarabine; Deoxycytidine; Deoxyribonucleosides; Drug Resistance; Humans; Kinetics; Leukemia, Myeloid, Acute; Phosphotransferases; Tritium

1974
Trisomy-9 in the bone marrow of a patient with acute myelomonoblastic leukaemia.
    British journal of haematology, 1974, Volume: 26, Issue:3

    Topics: Adult; Autopsy; Bone Marrow Cells; Chromosomes, Human, 6-12 and X; Cytarabine; Dactinomycin; Hemorrhage; Histocytochemistry; Humans; Kidney Neoplasms; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Lung Neoplasms; Male; Neoplasm Metastasis; Radiotherapy; Trisomy; Wilms Tumor

1974
[A case of spinal chloroma revealing acute leukemia].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1974, May-14, Volume: 50, Issue:23

    Topics: Adult; Asparaginase; Betamethasone; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Spinal Cord Compression; Spinal Neoplasms

1974
[Difficulties of remission induction treatment of acute myeloblastic leukemia].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1974, May-26, Volume: 50, Issue:25

    Topics: Adolescent; Adult; Aged; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission, Spontaneous; Thioguanine

1974
Adriamycin in the treatment of acute leukaemia.
    British medical journal, 1972, Feb-19, Volume: 1, Issue:5798

    Topics: Acute Disease; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Resistance; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Middle Aged; Remission, Spontaneous

1972
Enzymatic estimation and metabolism of 1- -D-arabinofuranosylcytosine in man.
    Cancer research, 1972, Volume: 32, Issue:2

    Topics: Adenosine Triphosphate; Adult; Chemistry, Clinical; Chromatography, DEAE-Cellulose; Chromatography, Thin Layer; Cytarabine; Half-Life; Humans; Leukemia, Myeloid, Acute; Male; Methods; Phosphorus Isotopes; Phosphotransferases

1972
Combination chemotherapy of adult acute nonlymphoblastic leukemia.
    Annals of internal medicine, 1972, Volume: 76, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Aged; Bone Marrow; Cytarabine; Drug Synergism; Female; Humans; Hydroxyurea; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Nausea; Remission, Spontaneous; Thioguanine; Vomiting

1972
[Therapeutic trials in acute myeloblastic leukosis. Analysis of a group of 51 patients treated with daunomycin].
    Sangre, 1972, Volume: 17, Issue:1

    Topics: Cytarabine; Daunorubicin; Evaluation Studies as Topic; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Prednisone; Remission, Spontaneous

1972
Characteristics of cell proliferation in acute leukemia.
    Cancer research, 1972, Volume: 32, Issue:5

    Topics: Adolescent; Adult; Autoradiography; Bone Marrow Cells; Cell Division; Child; Child, Preschool; Cytarabine; Daunorubicin; DNA, Neoplasm; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Prednisone; Thymidine; Tritium; Vincristine

1972
Cell kinetics and chemotherapy in acute leukemia.
    Seminars in hematology, 1972, Volume: 9, Issue:2

    Topics: Asparaginase; Autoradiography; Bone Marrow; Bone Marrow Cells; Bone Marrow Examination; Cells, Cultured; Cyclophosphamide; Cytarabine; DNA; Drug Combinations; Exchange Transfusion, Whole Blood; Humans; Hydrocortisone; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate; Methylprednisolone; Mitosis; Prednisone; Thymidine; Tritium; Vincristine

1972
[Treatment of acute myeloid leukaemia in adults with cytarabine and thioguanine].
    Deutsche medizinische Wochenschrift (1946), 1972, May-05, Volume: 97, Issue:18

    Topics: Adult; Age Factors; Aged; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Thioguanine; Time Factors

1972
The treatment of acute granulocytic leukemia in adults.
    The New England journal of medicine, 1972, Jun-01, Volume: 286, Issue:22

    Topics: Adult; Aged; Cytarabine; Daunorubicin; Female; Humans; Injections, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission, Spontaneous; Time Factors; Vincristine

1972
Acute granulocytic leukemia in adults.
    The New England journal of medicine, 1972, Jun-01, Volume: 286, Issue:22

    Topics: Adult; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Synergism; Humans; Leukemia, Myeloid, Acute; Prednisone; Remission, Spontaneous; Thioguanine; Time Factors; Vincristine

1972
[Experience in the therapy of acute leukemia in the period from March, 1959 to February, 1971].
    Minerva medica, 1972, Mar-31, Volume: 63, Issue:24

    Topics: Adolescent; Adult; Asparaginase; Child; Child, Preschool; Cytarabine; Evaluation Studies as Topic; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Remission, Spontaneous; Vincristine

1972
[Cytosine arabinoside in the polychemotherapy of acute leukemia].
    Minerva medica, 1972, Mar-31, Volume: 63, Issue:24

    Topics: Adolescent; Adult; Asparaginase; Child; Child, Preschool; Cytarabine; Drug Synergism; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Prednisone; Recurrence; Thioguanine; Vincristine

1972
[Should acute myeloblastic leukemias be treated in elderly patients?].
    La Nouvelle presse medicale, 1972, Apr-22, Volume: 1, Issue:17

    Topics: Age Factors; Aged; Antineoplastic Agents; Cytarabine; Daunorubicin; Drug Combinations; Drug Tolerance; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Recurrence; Remission, Spontaneous

1972
Treatment of acute granulocytic leukemia in adults.
    The New England journal of medicine, 1972, Aug-10, Volume: 287, Issue:6

    Topics: Adult; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Vincristine

1972
[Research on optimal dosage schemes in clinical experimentation with antineoplastic agents].
    Bollettino chimico farmaceutico, 1972, Volume: 111, Issue:2

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Cytarabine; Daunorubicin; Drug Combinations; Glycosides; Humans; Leukemia, Myeloid, Acute; Lung Neoplasms; Naphthacenes; Neoplasms

1972
Serum muramidase levels in acute leukemia.
    The American journal of the medical sciences, 1972, Volume: 264, Issue:1

    Topics: Adult; Aged; Blood Cell Count; Bone Marrow Cells; Bone Marrow Examination; Child; Cytarabine; Densitometry; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Muramidase; Remission, Spontaneous; Thioguanine; Vincristine

1972
The effect of remission induction in acute myeloblastic leukemia on efficiency of colony formation in culture.
    Series haematologica (1968), 1972, Volume: 5, Issue:2

    Topics: Asparaginase; Bone Marrow; Bone Marrow Cells; Bone Marrow Examination; Cells, Cultured; Cyclophosphamide; Cytarabine; Humans; Kinetics; Leukemia, Myeloid, Acute; Remission, Spontaneous; Suspensions; Vincristine

1972
[Effect of daunomycin and adriamycin in cytostatic combination therapy of acute leukoses of the adult].
    Medizinische Klinik, 1972, Aug-04, Volume: 67, Issue:31

    Topics: Acute Disease; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Blood Coagulation Disorders; Bone Marrow Diseases; Carbenicillin; Cytarabine; Daunorubicin; Drug Synergism; Female; Glycosides; Hair; Heart Diseases; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisolone; Remission, Spontaneous; Skin Diseases; Vincristine

1972
[Trial treatment of acute myeloblastic leukemia with the cytosine arabinoside-cyclophosphamide association. (Apropos of 30 cases)].
    Therapeutique (La Semaine des hopitaux), 1972, Volume: 48, Issue:4

    Topics: Adolescent; Adult; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Synergism; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission, Spontaneous

1972
DNA synthesis in normal and leucemic cells as related to therapy with cytotoxic drugs.
    Enzyme, 1972, Volume: 13, Issue:1

    Topics: Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Cytarabine; Daunorubicin; DNA; DNA Nucleotidyltransferases; DNA, Neoplasm; Doxorubicin; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocytes; Methotrexate; Prednisolone; Tetrahydrofolate Dehydrogenase; Thymidine Kinase; Thymine Nucleotides

1972
Pyrexia with cytosine arabinoside.
    British medical journal, 1972, Oct-14, Volume: 4, Issue:5832

    Topics: Aged; Cytarabine; Fever; Humans; Leukemia, Myeloid, Acute; Male

1972
Chronic myelogenous leukemia presenting in blastic crisis.
    Cancer, 1972, Volume: 30, Issue:4

    Topics: Adolescent; Adult; Cell Transformation, Neoplastic; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 21-22 and Y; Cyclophosphamide; Cytarabine; Diagnosis, Differential; Female; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Vincristine

1972
Intensive chemotherapy of acute myelogenous leukaemia.
    Journal of the Irish Medical Association, 1972, Oct-21, Volume: 65, Issue:20

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Vincristine

1972
Prediction of the response of patients with acute nonlymphocytic leukemia to cytosine arabinoside (NSC-63878) therapy.
    Cancer chemotherapy reports, 1972, Volume: 56, Issue:4

    Topics: Adult; Aged; Cytarabine; Female; Humans; Kinetics; Leukemia; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukocyte Count; Leukocytes; Male; Middle Aged; Remission, Spontaneous; Thymidine; Tritium

1972
[Treatment of acute myeloblastic leukemia with daunorubicin and cytosine-arabinoside].
    Ugeskrift for laeger, 1972, Oct-16, Volume: 134, Issue:42

    Topics: Adolescent; Adult; Aged; Child; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission, Spontaneous; Time Factors

1972
The outlook for the adult with acute leukaemia, 1972.
    The Medical journal of Australia, 1972, Aug-19, Volume: 2, Issue:8

    Topics: Acute Disease; Adolescent; Adult; Aged; Bacterial Infections; Cytarabine; Drug Combinations; Female; Hemorrhage; Humans; Hydroxyurea; Length of Stay; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Patient Isolators; Prednisone; Remission, Spontaneous; Thioguanine

1972
Treatment of acute myeloblastic leukemia in adults: remission induction with a combination of cyclophosphamide, cytarabine and vincristine.
    Canadian Medical Association journal, 1972, Dec-09, Volume: 107, Issue:11

    Topics: Adult; Age Factors; Cyclophosphamide; Cytarabine; Evaluation Studies as Topic; Female; Hepatitis; Hepatitis B Antigens; Hospitalization; Humans; Injections, Intravenous; Leukemia, Myeloid, Acute; Male; Muramidase; Remission, Spontaneous; Vincristine

1972
Acute myelocytic leukemia in adults.
    Cancer, 1972, Volume: 30, Issue:6

    Topics: Adult; Age Factors; Antineoplastic Agents; Cell Transformation, Neoplastic; Cytarabine; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Prognosis; Remission, Spontaneous; Thioguanine; United States

1972
Leukemia in arsenic poisoning.
    Annals of internal medicine, 1972, Volume: 77, Issue:6

    Topics: Aged; Anemia, Aplastic; Arsenic; Arsenic Poisoning; Autopsy; Biopsy; Bone Marrow Cells; Cytarabine; Environmental Exposure; Humans; Klebsiella Infections; Leukemia, Myeloid, Acute; Male; Oxymetholone; Penicillamine; Pesticides; Poisoning; Prednisone; Recurrence; Sepsis; Thioguanine

1972
Treatment of acute myeloid leukaemia with cytosine arabinoside and daunomycin in combination.
    Scandinavian journal of haematology, 1972, Volume: 9, Issue:6

    Topics: Adult; Aged; Aspergillosis; Bacterial Infections; Candidiasis; Cytarabine; Daunorubicin; Female; Humans; Infant; Injections, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission, Spontaneous; Time Factors

1972
[Therapy of acute leukemia. Opinion of Prof. Franco Mandelli].
    Minerva medica, 1973, Jan-20, Volume: 64, Issue:4

    Topics: Antineoplastic Agents; Asparaginase; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Drug Synergism; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Prednisone; Prognosis; Remission, Spontaneous; Thioguanine; Vincristine

1973
Acute myeloblastic leukemia during pregnancy.
    British medical journal, 1972, Nov-25, Volume: 4, Issue:5838

    Topics: Acute Disease; Cytarabine; Female; Humans; Infant, Newborn; Leukemia, Myeloid, Acute; Pregnancy; Pregnancy Complications, Hematologic; Thioguanine

1972
Remission of leukemia associated with polycythemia vera.
    JAMA, 1973, Jan-08, Volume: 223, Issue:2

    Topics: Adult; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Male; Methylprednisolone; Phosphorus Isotopes; Polycythemia Vera; Remission, Spontaneous; Thioguanine; Vincristine

1973
Hemorrhagic cystitis and vesicoureteral reflux secondary to cytotoxic therapy for childhood malignancies.
    The American journal of roentgenology, radium therapy, and nuclear medicine, 1973, Volume: 117, Issue:3

    Topics: Child, Preschool; Cyclophosphamide; Cystitis; Cytarabine; Eye Neoplasms; Female; Ganglioneuroma; Hematuria; Humans; Infant; Leukemia, Myeloid, Acute; Male; Neoplasms; Radiography; Retinoblastoma; Stomach Neoplasms; Urinary Bladder; Vesico-Ureteral Reflux

1973
Combination chemotherapy with cytosine arabinoside and rubidomycin in 30 cases of acute granulocytic leukemia.
    Cancer, 1973, Volume: 31, Issue:3

    Topics: Adult; Aged; Anemia, Aplastic; Cerebral Hemorrhage; Child; Cytarabine; Daunorubicin; Disseminated Intravascular Coagulation; Female; Humans; Infections; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission, Spontaneous

1973
Necrotizing enterocolitis in leukemia.
    Archives of internal medicine, 1973, Volume: 131, Issue:4

    Topics: Adult; Aged; Anti-Bacterial Agents; Antineoplastic Agents; Cecum; Colon; Cytarabine; Enterocolitis, Pseudomembranous; Female; Humans; Ileum; Infections; Leukemia, Myeloid, Acute; Male; Middle Aged; Necrosis; Prednisone; Radiography

1973
Acute leukemia presenting as a breast mass.
    JAMA, 1973, Mar-26, Volume: 223, Issue:13

    Topics: Acute Disease; Adolescent; Adult; Age Factors; Biopsy, Needle; Breast Neoplasms; Child; Cytarabine; Daunorubicin; Diagnosis, Differential; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Menarche; Mercaptopurine; Methotrexate; Prednisolone; Sulfates; Vincristine

1973
Optimism in leukemia treatment.
    Canadian Medical Association journal, 1973, Apr-07, Volume: 108, Issue:7

    Topics: Acute Disease; Adult; Child; Cyclophosphamide; Cytarabine; Humans; Hydroxyurea; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Prednisolone; Thioguanine; Vincristine

1973
[Cytosine arabinoside therapy of varicella, complicated in children with acute leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1973, Volume: 14, Issue:2

    Topics: Chickenpox; Child; Cytarabine; Humans; Leukemia, Myeloid, Acute; Male

1973
[Otitis and leukemia].
    Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Societe d'oto-laryngologie des hopitaux de Paris, 1973, Volume: 90, Issue:3

    Topics: Adult; Antineoplastic Agents; Cytarabine; Daunorubicin; Ear Neoplasms; Gentamicins; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Otitis; Otitis Externa; Punctures

1973
[Combined treatment of myeloid leukemia with cytosine arabinoside and 6-mercaptopurine].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1973, Jun-04, Volume: 28, Issue:23

    Topics: Cytarabine; Drug Synergism; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mercaptopurine

1973
Refractory leukemia treated with cytosine arabinoside and cyclophosphamide.
    Cancer, 1973, Volume: 32, Issue:2

    Topics: Adolescent; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Evaluation Studies as Topic; Female; Humans; Infant; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Prednisone; Remission, Spontaneous; Vincristine

1973
Treatment of acute myeloid leukaemia according to the Hammersmith protocol: preliminary report.
    British medical journal, 1973, Sep-15, Volume: 3, Issue:5880

    Topics: Adolescent; Adult; Age Factors; Aged; Child; Cytarabine; Daunorubicin; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; London; Middle Aged; Prednisolone; Remission, Spontaneous; Thioguanine

1973
Effects of chemotherapeutic agents on cell cycle and cellular proliferation: basic and clinical considerations.
    Transplantation proceedings, 1973, Volume: 5, Issue:3

    Topics: Autoradiography; Bone Marrow Cells; Cell Division; Cyclophosphamide; Cytarabine; DNA; Drug Antagonism; Drug Combinations; Hodgkin Disease; Humans; Hydrocortisone; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate; Mitosis; Thymidine; Tritium; Vincristine

1973
Our experience with cytosine arabinoside in the treatment of acute haemoblastoses.
    Neoplasma, 1973, Volume: 20, Issue:4

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Cytarabine; Evaluation Studies as Topic; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Remission, Spontaneous; Time Factors; Vincristine

1973
[Treatment of acute myeloblastic leukemia].
    Therapeutique (La Semaine des hopitaux), 1973, Volume: 49, Issue:3

    Topics: Antineoplastic Agents; Asparaginase; Blood Platelets; Blood Transfusion; Cyclophosphamide; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Remission, Spontaneous

1973
[The effects of cytosine arabinoside and daunomycin on cell kinetics in childhood acute myeloblastic leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1973, Volume: 14, Issue:7

    Topics: Bone Marrow; Bone Marrow Cells; Child; Child, Preschool; Cytarabine; Daunorubicin; Humans; In Vitro Techniques; Kinetics; Leukemia, Myeloid, Acute; Leukocytes; Mitosis

1973
[Acute myelogenous leukaemia of adults: diagnosis, prognosis and treatment (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1973, Sep-21, Volume: 98, Issue:38

    Topics: Adult; Cytarabine; Daunorubicin; Diagnosis, Differential; Drug Evaluation; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Muramidase; Prognosis; Remission, Spontaneous; Thymidine; Tritium

1973
Letter: Leukemic infiltration of the testes in acute myelocytic leukemia during bone marrow remission.
    The Journal of pediatrics, 1973, Volume: 83, Issue:5

    Topics: Bone Marrow; Child, Preschool; Cytarabine; Humans; Leukemia, Myeloid, Acute; Male; Neoplasm Metastasis; Remission, Spontaneous; Testicular Neoplasms

1973
Serial in vitro marrow culture in acute myelocytic leukemia.
    Blood, 1973, Volume: 42, Issue:5

    Topics: Adolescent; Adult; Bone Marrow Cells; Bone Marrow Examination; Cell Count; Cell Division; Child; Clone Cells; Culture Techniques; Cytarabine; Daunorubicin; Drug Therapy, Combination; Embryo, Mammalian; Female; Humans; Kidney; Leukemia, Myeloid, Acute; Leukocytes; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisolone; Remission, Spontaneous; Thioguanine; Vincristine

1973
Distribution of kinase and deaminase of 1-beta-D-arabinofuranosylcytosine in tissues of man and mouse.
    Cancer research, 1973, Volume: 33, Issue:11

    Topics: Aminohydrolases; Animals; Bone Marrow; Bone Marrow Cells; Cytarabine; Deoxycytidine; Humans; Kidney; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Liver; Mice; Phosphotransferases; Spleen; Uridine

1973
Acute granulocytic leukemia in elderly patients.
    JAMA, 1973, Dec-03, Volume: 226, Issue:10

    Topics: Adult; Age Factors; Aged; Bone Marrow Examination; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Remission, Spontaneous; Retrospective Studies; Time Factors

1973
Treatment of acute myeloid leukemia of adults with cytosine arabinoside in combination with 6-mercaptopurine.
    Cancer, 1973, Volume: 32, Issue:4

    Topics: Administration, Oral; Adult; Aged; Child; Cytarabine; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Remission, Spontaneous

1973
[A new approach to chemotherapeutic combinations in the treatment of solid tumors: trail synchronization, recruitement].
    Annales de medecine interne, 1973, Volume: 124, Issue:5

    Topics: Antineoplastic Agents; Cyclophosphamide; Cytarabine; Doxorubicin; Humans; Kinetics; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocyte Count; Methotrexate; Mitosis; Neoplasms; Vincristine

1973
Active immunotherapy used alone for maintenance of patients with acute myeloid leukaemia.
    British medical journal, 1973, Dec-08, Volume: 4, Issue:5892

    Topics: Adolescent; Adult; Aged; Bone Marrow Examination; Cytarabine; Daunorubicin; Female; Humans; Immunization; Immunotherapy; Leukemia, Myeloid, Acute; Leukocytes; Male; Middle Aged; Radiation Effects; Recurrence; Remission, Spontaneous; Time Factors

1973
[Therapy of acute leukemias].
    Schweizerische medizinische Wochenschrift, 1973, Sep-22, Volume: 103, Issue:38

    Topics: Adrenal Cortex Hormones; Asparaginase; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Humans; Hydroxyurea; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Thioguanine; Vincristine

1973
Acute leukemia in adults.
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1973, Sep-20, Volume: 93, Issue:26

    Topics: Adult; Agranulocytosis; Antineoplastic Agents; Cytarabine; Drug Therapy, Combination; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate; Prednisone; Thrombocytopenia; Time Factors

1973
Comparative chemotherapy of AKR lymphoma and human hematological neoplasia.
    Cancer research, 1974, Volume: 34, Issue:1

    Topics: Animals; Antineoplastic Agents; Biological Assay; Carmustine; Cyclohexanes; Cyclophosphamide; Cytarabine; Daunorubicin; Disease Models, Animal; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Fluorouracil; Hodgkin Disease; Humans; Leukemia; Leukemia L1210; Leukemia, Experimental; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma; Male; Mechlorethamine; Melphalan; Mice; Mice, Inbred AKR; Multiple Myeloma; Nitrosourea Compounds; Prednisone; Remission, Spontaneous; Vinblastine; Vincristine

1974
Perturbation of cell cycle of human leukaemic myeloblasts in vivo by cytosine arabinoside.
    Scandinavian journal of haematology, 1973, Volume: 10, Issue:3

    Topics: Adult; Aged; Autoradiography; Blood Cell Count; Bone Marrow; Bone Marrow Cells; Cell Division; Cell Survival; Cytarabine; Depression, Chemical; DNA; Erythrocytes; Humans; Injections, Intravenous; Leukemia, Myeloid, Acute; Middle Aged; Mitosis; Spectrophotometry; Thymidine; Time Factors; Tritium

1973
Adult acute leukaemia--a suitable case for treatment?
    Bristol medico-chirurgical journal (1963), 1973, Volume: 88, Issue:325

    Topics: Acute Disease; Adult; Aged; Agranulocytosis; Anemia; Blood Platelet Disorders; Blood Transfusion; Bone Marrow Diseases; Cytarabine; Daunorubicin; Female; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Mouth Diseases; Ulcer

1973
The therapy of acute granulocytic leukemia in patients more than fifty years old.
    Annals of internal medicine, 1974, Volume: 80, Issue:1

    Topics: Age Factors; Aged; Antineoplastic Agents; Connecticut; Cytarabine; Drug Combinations; Hospitals, Community; Hospitals, Special; Hospitals, Teaching; Humans; Leukemia, Myeloid, Acute; Middle Aged; Neoplasms; New York City; Prognosis; Remission, Spontaneous; Thioguanine

1974
[Therapy of acute leukemia. Results of the Swiss study group for clinical cancer research (SAKK)].
    Schweizerische medizinische Wochenschrift, 1974, Jan-26, Volume: 104, Issue:4

    Topics: Age Factors; Bone Marrow Examination; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Mercaptopurine; Nitrosourea Compounds; Prednisone; Remission, Spontaneous; Thioguanine; Vincristine

1974
[Morphology of megakaryocytes in hematologic diseases].
    Blut, 1974, Volume: 28, Issue:2

    Topics: Anemia, Pernicious; Blood Cell Count; Bone Marrow Cells; Cytarabine; Cytoplasm; Follow-Up Studies; Hematologic Diseases; Humans; In Vitro Techniques; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Megakaryocytes; Mercaptopurine; Plasmacytoma; Polycythemia; Thioguanine; Thrombocytopenia

1974
Hyponatraemia syndrome in acute myeloid leukaemia.
    British medical journal, 1974, Jan-12, Volume: 1, Issue:5897

    Topics: Adult; Ampicillin; Blood Cell Count; Body Weight; Bone Marrow Cells; Chlorides; Cloxacillin; Cytarabine; Daunorubicin; Diet; Female; Fever; Food Analysis; Gentamicins; Humans; Hyponatremia; Leukemia, Myeloid, Acute; Male; Middle Aged; Nitrogen; Osmolar Concentration; Potassium; Sodium; Syndrome; Urea

1974
Proceedings: Splenectomy and chemotherapy in acute myelocytic leukemia of childhood.
    Cancer, 1974, Volume: 33, Issue:2

    Topics: Adolescent; Adult; Age Factors; Azauridine; Child; Child, Preschool; Cytarabine; Drug Therapy, Combination; Female; Hepatomegaly; Humans; Leukemia, Myeloid, Acute; Liver; Lymph Nodes; Male; Mercaptopurine; Remission, Spontaneous; Spleen; Splenectomy; Splenomegaly; Vincristine

1974
Treatment of acute myeloblastic leukemia.
    Bibliotheca haematologica, 1973, Volume: 39

    Topics: Administration, Oral; Adult; Bone Marrow Examination; Cytarabine; DNA; Drug Therapy, Combination; Humans; Injections, Intravenous; Leukemia, Myeloid, Acute; Mitosis; Remission, Spontaneous; Thioguanine

1973
Pharmacologic and cytokinetic studies of arabinosyl cytosine.
    Bibliotheca haematologica, 1973, Volume: 39

    Topics: Adolescent; Adult; Animals; Antibody Formation; Cell Migration Inhibition; Child; Child, Preschool; Cyclophosphamide; Cytarabine; DNA; DNA Nucleotidyltransferases; Drug Therapy, Combination; Humans; Leukemia, Experimental; Leukemia, Myeloid, Acute; Lymphocyte Activation; Macrophages; Mice; Mitosis; Multiple Myeloma; Prednisone; Vincristine

1973
Combined chemotherapy of acute myeloblastic leukemia.
    Bibliotheca haematologica, 1973, Volume: 39

    Topics: Adult; Age Factors; Asparaginase; Child; Cytarabine; Daunorubicin; Doxorubicin; Drug Synergism; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Prednisone; Remission, Spontaneous; Vincristine

1973
Eventual control of clinical leukemia.
    Bibliotheca haematologica, 1973, Volume: 39

    Topics: Administration, Oral; Africa; Burkitt Lymphoma; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Injections, Spinal; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate; Prednisone; United States; Vincristine

1973
Clinical classification and evaluation of treatment response in acute myeloid leukaemia on the basis of differences of leukaemic cell differentiation.
    Scandinavian journal of haematology, 1973, Volume: 11, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Cell Differentiation; Cell Division; Cell Survival; Cytarabine; Daunorubicin; Depression, Chemical; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Humans; Infant; Leukemia, Myeloid, Acute; Leukocyte Count; Lymphocyte Activation; Male; Middle Aged; Prognosis; Stimulation, Chemical; Thioguanine; Vincristine

1973
Trisomy 8 in acute myeloblastic leukemia and sideroachrestic anemia.
    Blood, 1974, Volume: 43, Issue:4

    Topics: Aged; Anemia, Myelophthisic; Anemia, Sideroblastic; Bone Marrow Examination; Cells, Cultured; Chromosomes, Human, 6-12 and X; Cytarabine; Daunorubicin; Female; Folic Acid; Humans; Karyotyping; Lectins; Leukemia, Myeloid, Acute; Leukocytes; Middle Aged; Prednisolone; Pyridoxal Phosphate; Pyridoxine; Thioguanine; Trisomy

1974
The treatment of acute myeliod leukaemia.
    Journal of clinical pathology, 1974, Volume: 27, Issue:1

    Topics: Adolescent; Adult; Blood Cell Count; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Middle Aged; Remission, Spontaneous

1974
[Treatment of leukemia in children].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1974, Jan-30, Volume: 94, Issue:3

    Topics: Antineoplastic Agents; Asparaginase; Child; Child, Preschool; Cytarabine; Drug Therapy, Combination; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Prednisone; Time Factors

1974
[Kinetic effect of cytostatic drugs on the generation cycle of human leukaemic blast cells in vivo. A review].
    Ugeskrift for laeger, 1974, Mar-25, Volume: 136, Issue:13

    Topics: Antineoplastic Agents; Asparaginase; Bone Marrow; Bone Marrow Cells; Cytarabine; Daunorubicin; DNA Nucleotidyltransferases; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocytes; Methotrexate; Mitosis; Prednisone; Thymidine; Time Factors; Vincristine

1974
Treating acute leukaemia in special centres.
    Drug and therapeutics bulletin, 1973, Nov-09, Volume: 11, Issue:23

    Topics: Antineoplastic Agents; Cytarabine; Hospitals, Special; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Prednisolone; Prognosis

1973
[Treatment of acute myeloblastic leukemia. 79 cases treated by cytosine-rubidomycin combination].
    La Nouvelle presse medicale, 1974, Feb-09, Volume: 3, Issue:6

    Topics: Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Prognosis; Recurrence; Remission, Spontaneous; Statistics as Topic; Time Factors

1974
[Results of cytarabine and 6-thioguanine combination chemotherapy in acute leukemia].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1973, Volume: 79

    Topics: Adult; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Thioguanine

1973
[Electron microscopic bone marrow changes in acute leukemias before and after cytosin-arabinoside therapy].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1973, Volume: 79

    Topics: Bone Marrow; Cytarabine; Humans; Leukemia, Myeloid, Acute; Microscopy, Electron

1973
Development of pulmonary aspergillomas coinciding with induction of remission in acute myeloid leukaemia.
    Danish medical bulletin, 1974, Volume: 21, Issue:1

    Topics: Aged; Aspergillosis; Autopsy; Cytarabine; Daunorubicin; Diagnosis, Differential; Humans; Leukemia, Myeloid, Acute; Lung; Male; Radionuclide Imaging; Remission, Spontaneous; Strontium Radioisotopes

1974
Accumulation of S-phase cells in the bone marrow of patients with acute leukemia by cytosine arabinoside.
    Blut, 1974, Volume: 28, Issue:4

    Topics: Bone Marrow; Bone Marrow Examination; Cell Division; Cytarabine; DNA; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Photometry; Ribonucleases; RNA

1974
[Acute lymphatic leukemia in adults. Therapy and prognosis in comparison with acute myelogenous leukemia].
    Medizinische Klinik, 1974, Mar-08, Volume: 69, Issue:10

    Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Asparaginase; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Methylprednisolone; Middle Aged; Paresis; Prognosis; Radiotherapy Dosage; Remission, Spontaneous; Vincristine

1974
[Antimetabolites in the therapy of acute human leukoses. Mechanism of action and conditioning factors in the cellular response to drugs. I].
    La Clinica terapeutica, 1974, Apr-15, Volume: 69, Issue:1

    Topics: Aminopterin; Antimetabolites; Azaguanine; Cytarabine; DNA, Neoplasm; Humans; Immunity, Cellular; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Purines; Quinazolines; RNA, Neoplasm

1974
Agar culture studies in 127 cases of untreated acute leukemia: the prognostic value of reclassification of leukemia according to in vitro growth characteristics.
    Blood, 1974, Volume: 44, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Bone Marrow; Bone Marrow Cells; Cell Division; Cells, Cultured; Child; Clone Cells; Cytarabine; Daunorubicin; Densitometry; Drug Therapy, Combination; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Middle Aged; Prognosis; Remission, Spontaneous; Vincristine

1974
Letter: Leukemia in the elderly.
    Annals of internal medicine, 1974, Volume: 81, Issue:1

    Topics: Age Factors; Aged; Cytarabine; Humans; Leukemia, Myeloid, Acute; Thioguanine

1974
Chromosomes and causation of human cancer and leukemia. IX. Prognostic and therapeutic value of chromosomal findings in acute myeloblastic leukemia.
    Cancer, 1974, Volume: 33, Issue:6

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Bone Marrow Cells; Carmustine; Chromosome Aberrations; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitosis; Nitrosourea Compounds; Prednisone; Prognosis; Thioguanine; Time Factors; Vincristine

1974
A model for the chemotherapy of acute leukemia with 1-beta-D-arabinofuranosylcytosine.
    Cancer research, 1974, Volume: 34, Issue:8

    Topics: Adult; Cell Division; Cell Survival; Chromosomes; Cytarabine; DNA Replication; Drug Resistance; Humans; Leukemia, Myeloid, Acute; Male; Models, Biological; Oncogenic Viruses; RNA Viruses

1974
[Treatment of acute myeloblastic leukemia in patients over 60. Apropos of 22 cases].
    La Nouvelle presse medicale, 1974, Jun-29, Volume: 3, Issue:26

    Topics: Cytarabine; Daunorubicin; Drug Synergism; Glyoxal; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Remission, Spontaneous

1974
Serial studies of immunocompetence of patients undergoing chemotherapy for acute leukemia.
    The Journal of clinical investigation, 1974, Volume: 54, Issue:2

    Topics: Adolescent; Adult; Aged; Antibody Formation; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Follow-Up Studies; Humans; Hypersensitivity, Delayed; Immunotherapy; In Vitro Techniques; Lectins; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphocyte Activation; Lymphocytes; Middle Aged; Prednisone; Prognosis; Remission, Spontaneous; Skin Tests; Streptolysins; Vincristine

1974
[Cytosine-arabinoside in the treatment of acute leukemias].
    Wiener medizinische Wochenschrift (1946), 1972, Apr-08, Volume: 122, Issue:15

    Topics: Acute Disease; Adolescent; Adult; Aged; Child; Child, Preschool; Cytarabine; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Middle Aged; Polycythemia

1972
Alterations of granulopoiesis following chemotherapy.
    Blood, 1974, Volume: 44, Issue:3

    Topics: Adult; Aged; Blood Cell Count; Bone Marrow; Bone Marrow Cells; Cell Division; Clone Cells; Cytarabine; DNA; Doxorubicin; Female; Glycoproteins; Hematopoiesis; Humans; Leukemia, Myeloid, Acute; Lymphoma; Male; Mitosis; Muramidase; Thioguanine; Thymidine; Tritium

1974
Induction of remission with l-Asparaginase, cyclophosphamide, cytosine arabinoside, and prednisolone in adult patients with acute leukemia.
    Cancer, 1974, Volume: 34, Issue:2

    Topics: Adolescent; Adult; Age Factors; Aged; Asparaginase; Blood Cell Count; Child; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Liver Function Tests; Male; Middle Aged; Remission, Spontaneous; Sex Factors

1974
Primary amyloidosis and acute leukemia associated with melphalan therapy.
    Blood, 1974, Volume: 44, Issue:3

    Topics: Amyloidosis; Blood Cell Count; Blood Platelets; Blood Transfusion; Bone Marrow Examination; Cephalothin; Cytarabine; Erythrocytes; Gentamicins; Hemoglobins; Humans; Leukemia, Myeloid, Acute; Male; Melphalan; Middle Aged; Proteinuria; Thioguanine

1974
Prognosis of acute leukaemia in adults.
    The Medical journal of Australia, 1974, Jun-29, Volume: 1, Issue:26

    Topics: Acute Disease; Adult; Age Factors; Antineoplastic Agents; Child; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Middle Aged; Prednisolone; Prognosis; Remission, Spontaneous; Thioguanine; Vincristine

1974
Studies of leukemic cell populations in culture.
    Blood, 1974, Volume: 44, Issue:2

    Topics: Autoradiography; Bone Marrow Cells; Cell Adhesion; Cell Division; Cell Separation; Cells, Cultured; Culture Media; Cytarabine; Daunorubicin; Freezing; Humans; Lectins; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Male; Mercaptopurine; Middle Aged; Prednisone; Radiation Effects; Thymidine; Tritium; Ultrafiltration

1974
[Treatment of acute myeloblastic leukemia. Evaluation of six years of cooperative studies in Argentina (author's transl)].
    Sangre, 1974, Volume: 19, Issue:2

    Topics: Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Infant; Leukemia, Myeloid, Acute; Mercaptopurine; Middle Aged; Prednisone; Remission, Spontaneous; Vincristine

1974
Hypouricaemia and proximal renal tubular dysfunction in acute myeloid leukaemia.
    British medical journal, 1974, Sep-28, Volume: 3, Issue:5934

    Topics: Amino Acids; Calcium; Creatinine; Cytarabine; Daunorubicin; Female; Humans; Hydrogen-Ion Concentration; Kidney Diseases; Kidney Tubules, Proximal; Leukemia, Myeloid, Acute; Middle Aged; Muramidase; Phosphates; Phosphorus; Pyrazinamide; Uric Acid

1974
Pulmonary sequestration with spontaneous intrapleural hemorrhage.
    The Journal of thoracic and cardiovascular surgery, 1974, Volume: 68, Issue:4

    Topics: Adult; Bronchopulmonary Sequestration; Cytarabine; Hemorrhage; Humans; Leukemia, Myeloid, Acute; Lung Diseases; Male; Pneumonectomy; Thioguanine

1974
[Cytokinetic effect of cytosine arabinoside in clinical tests].
    Die Medizinische Welt, 1974, Sep-27, Volume: 25, Issue:39

    Topics: Adult; Animals; Bone Marrow Cells; Cell Division; Cytarabine; DNA; Female; Humans; Infusions, Parenteral; Kinetics; Leukemia, Myeloid, Acute; Male; Middle Aged; Patient Care Planning; Rats; Time Factors

1974
[Our experience in the treatment of acute myeloblastic leukemia].
    Minerva pediatrica, 1974, Nov-03, Volume: 26, Issue:34

    Topics: Antineoplastic Agents; Busulfan; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Thioguanine; Vincristine

1974
Comparative results obtained in the treatment of acute leukemia.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1973, Volume: 43

    Topics: Antineoplastic Agents; Asparaginase; Carmustine; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Hydroxyurea; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Meningitis; Methotrexate; Prednisone; Thioguanine; Vincristine

1973
Comparative results obtained in the treatment of acute lymphoid leukemia, acute myleoid leukemia, and acute monocytoid leukemia.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1973, Volume: 43

    Topics: Adult; Antineoplastic Agents; Asparaginase; Child; Cytarabine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Humans; Immunotherapy; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Prednisone; Remission, Spontaneous; Thioguanine; Time Factors; Vincristine

1973
Preliminary results of a trial on acute myeloid leukemia comparing the effect of cytosine arabinoside, the combination of cytosine arabinoside and thioguanine and the combination of cytosine arabinoside and daunorubicine.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1973, Volume: 43

    Topics: Age Factors; Bone Marrow Examination; Cytarabine; Daunorubicin; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission, Spontaneous; Thioguanine

1973
Chemotherapy of acute myelocytic leukemia in adults.
    Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society, 1974, Volume: 37, Issue:3

    Topics: Adolescent; Adult; Aged; Anhydrides; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisolone

1974
Cytosine arabinoside as a single agent in the therapy of adult acute leukemia.
    The American journal of the medical sciences, 1974, Volume: 268, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Age Factors; Aged; Anemia; Child; Cytarabine; DNA, Neoplasm; Female; Humans; Injections, Intravenous; Leukemia, Myeloid, Acute; Leukocytes; Male; Middle Aged; Muramidase; Nausea; Remission, Spontaneous; Sex Factors; Thioguanine; Thrombocytopenia; Time Factors; Vomiting

1974
[Treatment of complications induced by chemotherapy of acute leukemias].
    Revue medicale de Liege, 1974, Oct-01, Volume: 29, Issue:19

    Topics: Agranulocytosis; Anemia, Aplastic; Anti-Bacterial Agents; Antineoplastic Agents; Asparaginase; Blood Platelets; Blood Transfusion; Cytarabine; Daunorubicin; Drug Therapy, Combination; Hemorrhage; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocytes; Mercaptopurine; Methotrexate; Prednisone; Thrombocytopenia; Vincristine

1974
[Treatment of acute myelogenous leukemia in adults].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1972, Volume: 13, Issue:1

    Topics: Adult; Cyclophosphamide; Cytarabine; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Prednisolone

1972
[Combination chemotherapy for acute myelogenous leukemia in adults (author's transl)].
    Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society, 1974, Volume: 37, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Middle Aged; Prednisolone; Remission, Spontaneous; Thioinosine

1974
[Clinical evaluation of new antileukemic agent. 1) Cyclocytidine (author's transl)].
    Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society, 1974, Volume: 37, Issue:5

    Topics: Adult; Child; Cytarabine; Humans; Leukemia, Myeloid, Acute; Male; Remission, Spontaneous

1974
Development of a combination chemotherapy program for adult acute leukemia: CAM and CAM-L.
    Cancer, 1973, Volume: 32, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Evaluation Studies as Topic; Female; Humans; Leucovorin; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Remission, Spontaneous; Time Factors

1973
Correlation of cytosine arabinoside-induced increment in growth fraction of leukemic blast cells with clinical response.
    Cancer, 1974, Volume: 33, Issue:3

    Topics: Adult; Aged; Bone Marrow; Bone Marrow Cells; Cell Division; Cytarabine; DNA, Neoplasm; Drug Therapy, Combination; Female; Humans; Leucovorin; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Mitosis; Thymidine; Time Factors; Tritium

1974
Treatment of the acute leukemias.
    Seminars in hematology, 1972, Volume: 9, Issue:2

    Topics: Adjuvants, Immunologic; Asparaginase; Bacterial Vaccines; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Synergism; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Mycobacterium bovis; Prednisone; Remission, Spontaneous; Thioguanine; Vincristine

1972
[Treatment of acute myeloid leukemia in adults with a combination of daunomycin and cytosine-arabinoside].
    Ugeskrift for laeger, 1972, Oct-16, Volume: 134, Issue:42

    Topics: Adult; Aged; Bone Marrow Cells; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission, Spontaneous

1972
Immunotherapy of acute myelogenous leukemia in man.
    National Cancer Institute monograph, 1973, Volume: 39

    Topics: Antigens, Neoplasm; BCG Vaccine; Cross Reactions; Cytarabine; Daunorubicin; Evaluation Studies as Topic; Humans; Immunity, Cellular; Immunization; Leukemia, Myeloid, Acute; Mycobacterium bovis; Remission, Spontaneous

1973
Marrow grafting and immunotherapy in identical twins with hematologic malignancies.
    Transactions of the Association of American Physicians, 1973, Volume: 86

    Topics: Adolescent; Adult; Antigens, Neoplasm; Bone Marrow Cells; Bone Marrow Transplantation; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Diseases in Twins; Humans; Immunotherapy; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphocyte Transfusion; Transplantation, Homologous

1973
Active specific immunotherapy for acute myelogenous leukaemia.
    Johns Hopkins medical journal. Supplement, 1974, Volume: 3

    Topics: Adjuvants, Immunologic; Antigens, Bacterial; Antigens, Neoplasm; BCG Vaccine; Cytarabine; Daunorubicin; Freezing; Humans; Immunization; Immunotherapy; Leukemia, Myeloid, Acute; Leukocytes; Mycobacterium bovis; Neoplasm Transplantation; Radiation Effects; Remission, Spontaneous; Thioguanine; Time Factors; Transplantation, Homologous

1974
Acute myelogenous leukemia in two patients treated with azathioprine for nonmalignant diseases.
    The American journal of medicine, 1974, Volume: 57, Issue:6

    Topics: Adult; Azathioprine; Blood Cell Count; Blood Platelets; Bone Marrow; Bone Marrow Cells; Cytarabine; Daunorubicin; Graft Rejection; Hepatitis; Humans; Immunosuppression Therapy; Kidney Transplantation; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Prednisone; Thioguanine; Transplantation, Homologous

1974
Biochemical techniques for classification of leukemic cell types.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1973, Volume: 43

    Topics: Cytarabine; Cytological Techniques; DNA, Neoplasm; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Phosphorus

1973
[Cytosine arabinoside alone and in association to other drugs in the therapy of acute myeloblastic leukemia].
    Haematologica, 1972, Volume: 57, Issue:7

    Topics: Cyclophosphamide; Cytarabine; Daunorubicin; Drug Interactions; Humans; Leukemia, Myeloid, Acute; Vincristine

1972
[Cytosine arabinoside in the treatment of acute childhood leukemia: clinical contribution].
    Haematologica, 1972, Volume: 57, Issue:7

    Topics: Child; Child, Preschool; Cyclophosphamide; Cytarabine; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Prednisone; Vincristine

1972
[Kinetics of human leukemic myeloblasts after use of cytosine-arabinoside].
    Acta haematologica, 1973, Volume: 49, Issue:1

    Topics: Adolescent; Adult; Child; Child, Preschool; Cytarabine; Female; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Leukocytes; Male; Thymidine; Tritium

1973
Arabinosyl cytosine: a useful agent in the treatment of acute leukemia in adults.
    Blood, 1968, Volume: 32, Issue:4

    Topics: Adolescent; Adult; Aged; Blood Cell Count; Blood Platelets; Blood Transfusion; Bone Marrow Examination; Cell Nucleus; Cytarabine; Drug Tolerance; Erythrocytes; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocyte Count; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Middle Aged; Prednisone

1968
Fatal infection with Aeromonas hydrophila in a patient with acute myelogenous leukemia.
    Annals of internal medicine, 1967, Volume: 66, Issue:6

    Topics: Adolescent; Aeromonas; Cyclophosphamide; Cytarabine; Female; Humans; Immunosuppressive Agents; Joint Diseases; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Prednisone; Sepsis; Vincristine

1967
Prediction of in vivo cytotoxicity of chemotherapeutic agents by their effect on malignant leukocytes in vitro.
    Blood, 1967, Volume: 30, Issue:2

    Topics: Blood Cell Count; Cytarabine; DNA; Humans; In Vitro Techniques; Injections, Intravenous; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Mercaptopurine; Multiple Myeloma; Prednisone; RNA; Tritium; Uridine; Vincristine

1967
[Chemotherapy of acute leukemia].
    Deutsche medizinische Wochenschrift (1946), 1967, Dec-29, Volume: 92, Issue:52

    Topics: Acute Disease; Adrenal Cortex Hormones; Adult; Antineoplastic Agents; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Thrombocythemia, Essential; Vincristine

1967
Treatment of the acute leukemias.
    Cancer research, 1967, Volume: 27, Issue:12

    Topics: Antineoplastic Agents; Cyclophosphamide; Cytarabine; Daunorubicin; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Nitroso Compounds; Prednisone; Urea; Vincristine

1967
Therapy for acute granulocytic leukemia.
    Cancer research, 1967, Volume: 27, Issue:12

    Topics: Cytarabine; Humans; Infusions, Parenteral; Leukemia, Myeloid, Acute; Mercaptopurine

1967
Summary: recent advances in the treatment of acute leukemia and Burkitt's tumor.
    Cancer research, 1967, Volume: 27, Issue:12

    Topics: Antineoplastic Agents; Asparaginase; Burkitt Lymphoma; Cyclophosphamide; Cytarabine; Daunorubicin; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Nitroso Compounds; Prednisone; Urea; Vincristine

1967
Treatment of acute leukemia.
    Annals of internal medicine, 1968, Volume: 69, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents; Burkitt Lymphoma; Child; Child, Preschool; Cytarabine; Daunorubicin; Female; Humans; Infant; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Prognosis; Thioguanine; Time Factors; Vincristine

1968
Drugs in the treatment of leukemia.
    British medical journal, 1968, Nov-02, Volume: 4, Issue:5626

    Topics: Asparaginase; Busulfan; Chlorambucil; Cyclophosphamide; Cytarabine; Humans; Hydroxyurea; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Pipobroman; Prednisolone; Vincristine

1968
Treatment of AGL.
    Archives of internal medicine, 1969, Volume: 123, Issue:2

    Topics: Adult; Afibrinogenemia; Aged; Anemia; Antineoplastic Agents; Child; Cytarabine; Daunorubicin; Humans; Hydroxyzine; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukopenia; Mercaptopurine; Methotrexate; Middle Aged; Polycythemia Vera; Prednisone; Primary Myelofibrosis; Splenomegaly; Vincristine

1969
Treatment of AGL.
    Archives of internal medicine, 1969, Volume: 123, Issue:2

    Topics: Aminopterin; Cortisone; Cytarabine; Daunorubicin; Drug Tolerance; Drug-Related Side Effects and Adverse Reactions; Hemorrhage; Humans; Infections; Leukemia, Myeloid, Acute; Patient Isolators; Steroids; Transfusion Reaction

1969
Uptake and phosphorylation of cytosine arabinoside by normal and leukemic human blood cells in vitro.
    Cancer research, 1969, Volume: 29, Issue:2

    Topics: Blood Platelets; Cell Membrane Permeability; Cytarabine; Cytosine Nucleotides; Erythrocytes; Humans; In Vitro Techniques; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphocytes; Oxidative Phosphorylation; Temperature; Tritium

1969
Coordinated changes in biochemical patterns: the effect of cytosine arabinoside and methotrexate on leukocytes from patients with acute granulocytic leukemia.
    Cancer research, 1969, Volume: 29, Issue:3

    Topics: Acute Disease; Cytarabine; Deoxyuridine; DNA; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Ligases; Methotrexate; Phosphotransferases; Tetrahydrofolate Dehydrogenase; Thymidine; Thymidine Kinase

1969
Treatment of adult acute leukemia with arabinosylcytosine and thioguanine.
    Cancer, 1969, Volume: 23, Issue:5

    Topics: Adolescent; Adult; Aged; Cytarabine; Dosage Forms; Female; Humans; Injections, Intravenous; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Thioguanine

1969
Drug effect in acute leukemia.
    The Journal of clinical investigation, 1969, Volume: 48, Issue:6

    Topics: Adolescent; Bone Marrow; Bone Marrow Cells; Child; Child, Preschool; Cytarabine; DNA, Neoplasm; Humans; Hydrocortisone; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mitosis; Prednisone; Thymidine; Tritium; Vincristine

1969
[Experiences with daunomycin and cytosine arabinoside in the therapy of acute myeloid leukemias].
    Medizinische Klinik, 1968, Dec-20, Volume: 63, Issue:51

    Topics: Adolescent; Adult; Cytarabine; Daunorubicin; Female; Hematopoiesis; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged

1968
Hypersplenism due to disseminated candidiasis in a patient with acute leukemia.
    Cancer, 1969, Volume: 24, Issue:2

    Topics: Acute Disease; Adult; Amphotericin B; Blood Cell Count; Blood Platelets; Candida; Candidiasis; Cytarabine; Feces; Fever; Humans; Hypersplenism; Leukemia; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Nose; Pharynx; Prednisone; Skin; Spleen

1969
Comparative sensitivity to various antimetabolites of several established cell lines derived from the buffy coat of normal humans and patients with neoplastic diseases.
    Cancer research, 1969, Volume: 29, Issue:6

    Topics: Antimetabolites; Blood Cells; Cell Line; Culture Techniques; Cytarabine; Fluorouracil; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Mitosis; Neoplasms

1969
Studies on the effects of hydroxyurea and other anticancer drugs upon pyrimidine metabolism.
    Cancer research, 1969, Volume: 29, Issue:7

    Topics: Amidohydrolases; Animals; Antineoplastic Agents; Ascites; Carbon Isotopes; Cyclophosphamide; Cytarabine; Deoxyuridine; DNA; Fluorouracil; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Leukocytes; Methotrexate; Mice; Neoplasms, Experimental; Orotic Acid; Pyrimidines; Transferases; Triazines

1969
Review of recent studies of cellular proliferation in acute leukemia.
    National Cancer Institute monograph, 1969, Volume: 30

    Topics: Adolescent; Adult; Autoradiography; Bone Marrow; Bone Marrow Cells; Cell Division; Cell Nucleus; Cytarabine; DNA, Neoplasm; Female; Humans; Karyometry; Leukemia, Myeloid, Acute; Male; Mitosis; Thymidine; Tritium

1969
[Abnormalities of the erythropoiesis at the beginning of remission in acute promyelocytic leukemia treated with arabinoside-cytosine].
    Schweizerische medizinische Wochenschrift, 1970, Feb-14, Volume: 100, Issue:7

    Topics: Anemia, Aplastic; Bone Marrow Examination; Cell Nucleus; Child; Cytarabine; Erythrocytes; Erythropoiesis; Humans; Leukemia, Myeloid, Acute; Male; Megakaryocytes; Methotrexate; Mitosis; Reticulocytes; Thioguanine

1970
Intrathecal arabinosyl cytosine in meningeal leukemia.
    Cancer, 1970, Volume: 25, Issue:3

    Topics: Adolescent; Brain Neoplasms; Cerebrospinal Fluid; Child; Child, Preschool; Cytarabine; Female; Humans; Injections, Spinal; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Meninges; Time Factors

1970
Experience with the use of cytosine arabinoside in adult acute leukaemia.
    The Medical journal of Australia, 1970, Mar-28, Volume: 1, Issue:13

    Topics: Acute Disease; Adolescent; Adult; Cyclophosphamide; Cytarabine; Female; Humans; Injections, Intravenous; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged

1970
Preliminary evaluation of cyclophosphamide (NSC-26271) and cytosine arabinoside (NSC-63878) in acute leukemia of children.
    Cancer chemotherapy reports, 1969, Volume: 53, Issue:5

    Topics: Adolescent; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Female; Humans; Infant; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male

1969
The treatment of acute lymphocytic leukemia.
    Journal of chronic diseases, 1970, Volume: 22, Issue:10

    Topics: Animals; Antineoplastic Agents; Asparaginase; Blood Platelets; Bone Marrow Cells; Cyclophosphamide; Cytarabine; Daunorubicin; Disease Models, Animal; Drug Synergism; Hemorrhage; Humans; Infections; Leukemia L1210; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Mice; Prednisone; Prognosis; Thrombocytopenia; Vincristine

1970
[Effect of cytosine-arabinoside in hemoblastoses].
    Vnitrni lekarstvi, 1970, Volume: 16, Issue:7

    Topics: Bone Marrow Diseases; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Leukocytes; Male; Middle Aged; Monocytes; Polycythemia

1970
[Treatment of acute myeloid leukemia by the combination therapy of 6-mercaptopurine and cytosine arabinoside--evaluation of twenty-two cases].
    Saishin igaku. Modern medicine, 1970, Volume: 25, Issue:9

    Topics: Adolescent; Adult; Aged; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged

1970
Treatment of acute myeloblastic leukaemia.
    British medical journal, 1970, Nov-28, Volume: 4, Issue:5734

    Topics: Acute Disease; Adult; Child; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute

1970
Leukemia and lymphoma.
    Geriatrics, 1970, Volume: 25, Issue:12

    Topics: Antineoplastic Agents; BCG Vaccine; Burkitt Lymphoma; Busulfan; Chlorambucil; Cyclophosphamide; Cytarabine; Hodgkin Disease; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma; Lymphoma, Non-Hodgkin; Prednisone; Vincristine

1970
[Therapy of acute myeloblastic leukemia. Thoughts after preliminary results].
    Nordisk medicin, 1970, Dec-03, Volume: 84, Issue:49

    Topics: Acute Disease; Adult; Cyclophosphamide; Cytarabine; Female; Humans; Intensive Care Units; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisolone; Vincristine

1970
[Cytosine-arabinoside in the treatment of acute myeloblastic leukemias].
    Minerva medica, 1971, Mar-14, Volume: 62, Issue:21

    Topics: Adult; Cytarabine; Female; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male

1971
[Therapeutic evolution of 63 cases of recent acute myeloblastic leukemias].
    Lyon medical, 1971, Feb-14, Volume: 225, Issue:3

    Topics: Acute Disease; Aged; Antineoplastic Agents; Asparaginase; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Prednisone; Vincristine

1971
[Treatment of acute leukemia].
    L'union medicale du Canada, 1970, Volume: 99, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Antibiotics, Antineoplastic; Antilymphocyte Serum; Antineoplastic Agents; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Drug Synergism; Female; Humans; Immunotherapy; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Prednisone; Vincristine

1970
Normal fetus after cytosine arabinoside therapy.
    Annals of internal medicine, 1971, Volume: 74, Issue:6

    Topics: Adult; Birth Weight; Cytarabine; Female; Fetus; Gestational Age; Humans; Leukemia, Myeloid, Acute; Pregnancy; Pregnancy Complications, Hematologic; Thioguanine; Vincristine

1971
L-asparaginase: clinical, biochemical, pharmacological, and immunological studies.
    Annals of internal medicine, 1971, Volume: 74, Issue:6

    Topics: Adolescent; Adult; Antibody Formation; Antineoplastic Agents; Asparaginase; Asparagine; Bone Marrow Examination; Child; Child, Preschool; Cytarabine; Drug Hypersensitivity; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisone; Remission, Spontaneous

1971
[Cytosine arabinoside in the therapy of acute leukoses].
    Minerva medica, 1971, Jun-06, Volume: 62, Issue:45

    Topics: Adolescent; Adult; Child; Cytarabine; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone

1971
Cytarabine.
    The Medical letter on drugs and therapeutics, 1971, Jan-08, Volume: 13, Issue:1

    Topics: Acute Disease; Amino Sugars; Anemia; Antibiotics, Antineoplastic; Antineoplastic Agents; Blood Cell Count; Cyclophosphamide; Cytarabine; Glycosides; Humans; Injections, Intravenous; Injections, Subcutaneous; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukopenia; Lymphoma; Prednisone; Remission, Spontaneous; Thioguanine; Thrombocytopenia; Vincristine

1971
Cytogenetic studies and their clinical correlates in adults with acute leukemia.
    Annals of internal medicine, 1971, Volume: 75, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aneuploidy; Bone Marrow Cells; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 13-15; Chromosomes, Human, 16-18; Chromosomes, Human, 21-22 and Y; Chromosomes, Human, 6-12 and X; Cyclophosphamide; Cytarabine; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisone; Recurrence; Remission, Spontaneous; Vincristine

1971
Treatment of acute myelogenous leukaemia in adults.
    British journal of haematology, 1971, Volume: 21, Issue:3

    Topics: Adult; BCG Vaccine; Cell Division; Cytarabine; Daunorubicin; Humans; Injections, Intravenous; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Neoplasm Transplantation; Transplantation, Autologous; Transplantation, Homologous

1971
Serologic diagnosis of systemic candidiasis in patients with acute leukemia.
    The American journal of medicine, 1971, Volume: 51, Issue:1

    Topics: Adult; Agglutination Tests; Amphotericin B; Anti-Bacterial Agents; Candida; Candidiasis; Child; Cyclophosphamide; Cytarabine; Evaluation Studies as Topic; False Negative Reactions; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Nitrosourea Compounds; Precipitin Tests; Prednisone; Serologic Tests; Vinblastine; Vincristine

1971
Experiences with cytosine arabinoside in childhood leukaemia and lymphoma.
    The Medical journal of Australia, 1971, Jul-24, Volume: 2, Issue:4

    Topics: Acute Disease; Adolescent; Central Nervous System Diseases; Child; Child, Preschool; Cytarabine; Female; Humans; Infant; Injections, Intravenous; Injections, Spinal; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Neoplasm Regression, Spontaneous

1971
The disappearance of ring sideroblasts in myeloblastic leukaemia in remission.
    Scandinavian journal of haematology, 1971, Volume: 8, Issue:3

    Topics: Adult; Asparaginase; Blood Transfusion; Bone Marrow; Cytarabine; Daunorubicin; Erythrocytes; Erythrocytes, Abnormal; Female; Humans; Iron; Leukemia, Myeloid, Acute; Mercaptopurine; Prednisone; Remission, Spontaneous

1971
Case report: tetraploid leukemia.
    Blood, 1971, Volume: 38, Issue:5

    Topics: Aged; Antifungal Agents; Bone Marrow Examination; Candida; Cyclophosphamide; Cytarabine; Gentamicins; Hematopoietic Stem Cells; Humans; Karyotyping; Klebsiella; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Polyploidy; Prednisone; Urine; Vincristine

1971
Cytidine deaminase and the development of resistance to arabinosyl cytosine.
    Nature: New biology, 1971, Sep-22, Volume: 233, Issue:38

    Topics: Adult; Aminohydrolases; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Cyclophosphamide; Cytarabine; Cytidine; Drug Resistance; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Spectrum Analysis; Time Factors

1971
Observations on the plasma amino acids of patients with acute leukemia.
    Cancer research, 1971, Volume: 31, Issue:8

    Topics: Acute Disease; Alanine; Amino Acids; Asparaginase; Cytarabine; Glucocorticoids; Glutamine; Histidine; Humans; Indicators and Reagents; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Methionine; Methotrexate; Nitrogen; Proline; Threonine; Vincristine

1971
[Treatment of acute leukemias in the infancy with cytosine arabinoside].
    Minerva pediatrica, 1971, Jun-30, Volume: 23, Issue:26

    Topics: Acute Disease; Child, Preschool; Cytarabine; Female; Humans; Infant; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Remission, Spontaneous

1971
Cytosine arabinoside in acute leukemia of childhood.
    Cancer, 1971, Volume: 28, Issue:4

    Topics: Child; Cytarabine; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukopenia; Remission, Spontaneous; Thrombocytopenia; Vomiting

1971
Therapy of acute leukemia with drug combinations which include asparaginase.
    Cancer, 1971, Volume: 28, Issue:4

    Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Antineoplastic Agents; Asparaginase; Azaserine; Child; Child, Preschool; Cytarabine; Female; Glutamine; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisolone; Remission, Spontaneous; Vincristine

1971
Attempted recruitment of leukemic myeloblasts to proliferative activity by sequential drug treatment.
    Cancer, 1971, Volume: 28, Issue:4

    Topics: Adult; Autoradiography; Bone Marrow; Bone Marrow Cells; Culture Techniques; Cyclophosphamide; Cytarabine; DNA, Neoplasm; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Mitosis; Models, Biological; Remission, Spontaneous; Thymidine; Tritium; Vincristine

1971
Remission of leukemia associated with multiple myeloma.
    The New England journal of medicine, 1971, Oct-14, Volume: 285, Issue:16

    Topics: Cytarabine; Humans; Leukemia, Myeloid, Acute; Male; Melphalan; Middle Aged; Multiple Myeloma; Remission, Spontaneous

1971
Chemotherapy, immunocompetence, immunosuppression and prognosis in acute leukemia.
    The New England journal of medicine, 1971, 11-25, Volume: 285, Issue:22

    Topics: Adult; Aged; Antibodies; Antigens; Cyclophosphamide; Cytarabine; Female; Hemocyanins; Humans; Hypersensitivity, Delayed; Immunity, Cellular; Immunologic Deficiency Syndromes; Immunosuppression Therapy; Lectins; Leukemia, Myeloid, Acute; Leukocyte Count; Lymphocyte Activation; Lymphocytes; Male; Mercaptopurine; Methotrexate; Prednisone; Prognosis; Remission, Spontaneous; Skin Tests; Thioguanine; Vincristine

1971
Plasma half-life of cytosine arabinoside (NSC-63878) in patients treated for acute myeloblastic leukemia.
    Cancer chemotherapy reports, 1971, Volume: 55, Issue:3

    Topics: Animals; Culture Techniques; Cytarabine; DNA; Half-Life; Humans; Injections, Intravenous; L Cells; Leukemia, Myeloid, Acute; Male; Methods; Mice; Spleen; Thymidine; Tritium

1971
Synchronization and recruitment in acute leukemia.
    The Journal of clinical investigation, 1971, Volume: 50, Issue:10

    Topics: Adult; Antineoplastic Agents; Asparaginase; Bone Marrow; Bone Marrow Cells; Child; Culture Techniques; Cyclophosphamide; Cytarabine; Deoxyuridine; Depression, Chemical; DNA, Neoplasm; Exchange Transfusion, Whole Blood; Humans; Hydrocortisone; Kinetics; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Methotrexate; Mitosis; Thymidine; Tritium; Vincristine

1971
Fetal group C trisomy after cytosine arabinoside and thioguanine.
    Annals of internal medicine, 1971, Volume: 75, Issue:5

    Topics: Abnormalities, Drug-Induced; Abortion, Therapeutic; Adult; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 6-12 and X; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Mosaicism; Pregnancy; Pregnancy Complications, Hematologic; Thioguanine; Trisomy

1971
Leukaemia on myeloma.
    British medical journal, 1971, Nov-20, Volume: 4, Issue:5785

    Topics: Adult; Bronchopneumonia; Cytarabine; Humans; Leukemia, Myeloid, Acute; Male; Melphalan; Multiple Myeloma; Plasmacytoma; Thioguanine

1971
[Therapy of acute leukemia. 4. Remission induction and remission maintenance therapy].
    Saishin igaku. Modern medicine, 1971, Volume: 26, Issue:10

    Topics: Acute Disease; Adolescent; Adrenal Cortex Hormones; Adult; Age Factors; Aged; Asparaginase; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Middle Aged; Remission, Spontaneous; Vincristine

1971
[Experiences in the treatment of immature cell leukemias with cytosine arabinoside and daunorubidomycin].
    Wiener klinische Wochenschrift, 1971, Jun-25, Volume: 83, Issue:25

    Topics: Adolescent; Adult; Aged; Agranulocytosis; Allopurinol; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Blood Transfusion; Cytarabine; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Middle Aged; Muramidase; Nausea; Prednisolone; Thrombocytopenia; Vincristine

1971
Advances in the chemotherapy of malignant disease.
    The Practitioner, 1971, Volume: 207, Issue:240

    Topics: Antibiotics, Antineoplastic; Asparaginase; Cytarabine; Drug Combinations; Hodgkin Disease; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Medication Systems, Hospital; Neoplasms

1971
Cytosine arabinoside therapy for acute myeloid leukaemia in adults.
    The New Zealand medical journal, 1971, Volume: 74, Issue:471

    Topics: Abdomen; Adolescent; Adult; Aged; Alopecia; Bone Marrow Diseases; Chemical and Drug Induced Liver Injury; Cytarabine; Diarrhea; Erythrocytes; Female; Fever; Humans; Infusions, Parenteral; Injections, Intravenous; Kidney Diseases; Leukemia, Myeloid, Acute; Male; Middle Aged; Nausea; Ulcer; Vomiting

1971
Selecting drug regimens in human leukemia.
    National Cancer Institute monograph, 1971, Volume: 34

    Topics: Antineoplastic Agents; Cell Membrane Permeability; Child; Cyclophosphamide; Cytarabine; Drug Combinations; Drug Resistance; Follow-Up Studies; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Nucleotides; Prednisone; Prognosis; Vincristine

1971
DNA synthesis in leukemic cells under the action of cytotoxic agents in vitro and in vivo.
    National Cancer Institute monograph, 1971, Volume: 34

    Topics: Adult; Aged; Antineoplastic Agents; Cells, Cultured; Cytarabine; Daunorubicin; DNA, Neoplasm; Female; Glucocorticoids; Humans; In Vitro Techniques; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocytes; Male; Methotrexate; Middle Aged; Prognosis; Thymine Nucleotides; Tritium

1971
[Treatment of acute leukosis in children with arabinosyl cytosine].
    Schweizerische medizinische Wochenschrift, 1971, Dec-11, Volume: 101, Issue:49

    Topics: Adolescent; Anti-Bacterial Agents; Asparaginase; Blood Platelets; Blood Transfusion; Bone Marrow Diseases; Child; Child, Preschool; Cytarabine; Humans; Infant; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Remission, Spontaneous

1971
Advances in the chemotherapy of acute leukemia.
    Bibliotheca haematologica, 1970, Issue:36

    Topics: Adult; Animals; Blood Platelets; Blood Transfusion; Carbenicillin; Child; Cyclophosphamide; Cytarabine; Folic Acid Antagonists; Glucocorticoids; Humans; Leukemia L1210; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Nitrogen Mustard Compounds; Patient Isolators; Purines; Remission, Spontaneous

1970
Treatment of adult leukemia with L-asparaginase (NSC-109229).
    Cancer chemotherapy reports, 1971, Volume: 55, Issue:3

    Topics: Adolescent; Adult; Aged; Allopurinol; Anaphylaxis; Asparaginase; Blood Coagulation Disorders; Cytarabine; Daunorubicin; Drug Hypersensitivity; Female; Fever; Gastrointestinal Hemorrhage; Hallucinations; Humans; Hyperglycemia; Injections, Intravenous; Jaundice; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Liver; Male; Mercaptopurine; Methotrexate; Middle Aged; Oral Hemorrhage; Prednisone; Thioguanine; Uremia; Vincristine; Vomiting

1971