cytarabine has been researched along with Acute Lymphoid Leukemia in 781 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 47 (6.02) | 18.7374 |
1990's | 293 (37.52) | 18.2507 |
2000's | 249 (31.88) | 29.6817 |
2010's | 154 (19.72) | 24.3611 |
2020's | 38 (4.87) | 2.80 |
Authors | Studies |
---|---|
Chatla, S; Chowdhury, FA; Du, W; Geldenhuys, W; Lin, Q; Wu, L | 1 |
Hama, A; Hara, J; Hasegawa, D; Hiramatsu, H; Horibe, K; Imamura, T; Ishida, H; Kaino, A; Katayama, S; Kitazawa, H; Moriya, K; Moriya-Saito, A; Okamoto, K; Sasahara, Y; Sato, A; Sekimizu, M; Suenobu, S; Uemura, S; Usami, I; Yokoyama, N | 1 |
Becker, PS; Cassaday, RD; Cherian, S; Estey, EH; Garcia, KA; Halpern, AB; Keel, SB; Martino, CH; Oehler, VG; Orozco, JJ; Percival, MM; Shustov, AR; Stevenson, PA; Walter, RB | 1 |
Aguilar Martínez, JC; Campos Gonzaga, L; García Martínez, A; Mateos Millán, D | 1 |
Huang, HM; Wang, D; Wei, YJ; Wen, XM | 1 |
Anani-Sarab, G; Rastgar, A; Sajjadi, SM; Sayadi, M | 1 |
Boufrikha, W; Boughammoura, A; Laatiri, MA; Lakhal, S; Rakez, R | 1 |
Beck, J; Fuellen, G; Gladbach, YS; Hamed, M; Junghanss, C; Murua Escobar, H; Roolf, C; Schütz, E; Sklarz, LM | 1 |
Bojalil-Álvarez, L; Cortés, JE; Fernández-Gutiérrez, JA; García-Villaseñor, E; Murrieta-Álvarez, I; Reyes-Cisneros, OA; Ruiz-Argüelles, GJ; Ruiz-Delgado, GJ; Sánchez-Bonilla, D | 1 |
Falcón, MF; Fernández, SI; Ingold, JJ; Legnoverde, S; Manzella, PO; Melero, MJ; Santarelli, IM | 1 |
Tomizawa, D | 1 |
Dabaja, BS; Fang, PQ; Nasr, L; Short, NJ; Wu, SY | 1 |
Atchley, E; Derkach, A; DeWolf, S; Galera, PK; Glass, J; Roshal, M; Shah, R; Stump, SE; Weis, TM; Xiao, W | 1 |
Jiang, S; Tang, Y; Zhao, L; Zhao, Y | 1 |
Benesch, M; Egger, M; Flaschberger, S; Gorkiewicz, G; Karastaneva, A; Kohlmaier, B; Lackner, H; Marterer, R; Seidel, M; Sperl, D; Strenger, V; Trobisch, A; Urban, C | 1 |
Chen, BA; Ding, JH; Ge, Z; Sun, AN; Wu, DP; Yu, ZP | 1 |
Aguiar, M; Akarca, A; Aref, S; Bailey, K; Burt, R; Cheuk Yan Ng, K; Day, W; Dey, A; Fielding, AK; Hooper, S; Kirkwood, A; Kirschner, K; Lee, SW; Lo Celso, C; Manji, J; Mansour, MR; Marafioti, T; Mitchell, RJ; Muirhead, RC; Pospori, C; Puccio, I; Sahai, E; Zuborne-Alapi, K | 1 |
Kok, NTM; Ligthart-Beukhof, AC; van de Wetering, MD | 1 |
Altini, M; Bolognese, A; Bravaccini, S; Catalano, L; Cerchione, C; De Giorgi, U; De Nisco, M; Di Rorà, AGL; Dora Iula, V; Manfra, M; Marra, N; Martinelli, G; Martinelli, V; Pagano, F; Pane, F; Pedatella, S; Picardi, M; Pugliese, N; Ronconi, S; Simonetti, G | 1 |
Jayakumar, I; Patel, S; Raj, R; Ramakrishnan, B; Ramanan, KM; Ravichandran, N; Swaminathan, VV; Uppuluri, R | 1 |
Fan, R; Fang, Z; Guo, R; Liu, Z; Sun, Y; Wang, X; Xie, D | 1 |
Jabbour, EJ; Kadia, TM; Kantarjian, HM; Rausch, CR | 1 |
Attarbaschi, A; Bader, P; Barisone, E; Basso, G; Biondi, A; Cario, G; Caterina Putti, M; Cazzaniga, G; Colombini, A; Conter, V; Flotho, C; Kuhlen, M; Lang, P; Lauten, M; Linderkamp, C; Lo Nigro, L; Locatelli, F; Mann, G; Möricke, A; Niggli, F; Panzer-Grümayer, R; Parasole, R; Peters, C; Rizzari, C; Schrappe, M; Suttorp, M; Valsecchi, MG; Zimmermann, M | 1 |
Akane, Y; Hori, T; Igarashi, K; Takebayashi, A; Yamamoto, M | 1 |
Campana, D; Cheng, C; Coustan-Smith, E; Lins, MM; Lucena-Silva, N; Pedrosa, A; Pedrosa, F; Pedrosa, M; Ramos, AML; Ribeiro, RC; Rivera, GK; Vinhas, E; Zhou, Y | 1 |
Alten, J; Behrens, YL; Bergmann, AK; Buchmann, S; Cario, G; Cazzaniga, G; Davenport, CF; Ebersold, J; Fazio, G; Göhring, G; Hagedorn, M; Hofmann, W; Lentes, J; Möricke, A; Schieck, M; Schlegelberger, B; Schrappe, M; Stanulla, M; Steinemann, D; Thomay, K | 1 |
García-Hernández, MH; Godina-González, S; Medina-Rosales, MN | 1 |
Beaumont, AL; Suner, L | 1 |
Han, Y; Meng, T; Qiu, H; Sun, A; Tang, X; Wang, Y; Wu, D; Xu, Y; Xue, S; Yao, Y; Zhang, Y | 1 |
Banavali, S; Gujral, S; Myint, HH; Narula, G; Patkar, N; Prasad, M; Subramanian, P; Tandon, S; Tembhare, P | 1 |
Abdelhafiz, A; Elfishawi, S; Gameel, A; Ibraheem, D; Kamel, A; Madney, Y; Osman, R; Radwan, E; Rasekh, EO | 1 |
Candoni, A; Canichella, M; Cavalli, M; Chiaretti, S; Conter, V; D'Aloisio, M; De Propris, MS; Elia, L; Fazi, P; Foà, R; Guarini, A; Luppi, M; Martino, B; Messina, M; Moleti, ML; Piciocchi, A; Starza, ID; Testi, AM; Vignetti, M; Vitale, A | 1 |
Fan, J; Fang, C; Sun, M; Tian, X; Zhang, H; Zhang, R; Zheng, H; Zheng, X | 1 |
Chen, HQ; Fang, JP; Li, CG; Li, CK; Li, JQ; Li, XY; Lin, YD; Liu, RY; Luo, XQ; Sun, X; Sun, XF; Wu, XD; Xu, HG | 1 |
Bagal, B; Bonda, VNA; Chatterjee, G; Gokarn, A; Jain, H; Khattry, N; Mokal, S; Nayak, L; Patkar, N; Punatar, S; Rajendra, A; Sengar, M; Shetty, D; Subramanian, PG; Tembhare, P; Thorat, J | 1 |
Chen, C; Gu, H; Hao, X; Huang, D; Lai, X; Liu, L; Lu, Z; Shao, H; Xie, L; Xu, J; Yang, Y; Yu, Z; Zhang, T; Zhang, X; Zhao, Y; Zheng, J; Zhu, J | 1 |
Arndt, GM; Bongers, A; Cheung, LC; Failes, T; Gifford, AJ; Haber, M; Henderson, MJ; Karsa, M; Kees, UR; Kosciolek, A; Kotecha, RS; Lock, RB; Mariana, A; Norris, MD; Somers, K; Sutton, R | 1 |
Hu, BF; Shen, SH; Wang, GL; Wang, J | 1 |
Cheng, C; Crews, KR; Evans, WE; Finch, ER; Gruber, TA; Inaba, H; Jeha, S; Karol, SE; Kornegay, NM; Liu, Y; Metzger, ML; Panetta, JC; Pei, D; Pui, CH; Relling, MV; Ribeiro, RC; Rubnitz, JE; Smith, CA; Yang, JJ; Yang, W | 1 |
Cheng, L; Tu, L; Wang, X; Yan, D; Yang, Y; Zeng, S; Zheng, X | 1 |
Borkhardt, A; Dilloo, D; Escherich, G; Faber, J; Feuchtinger, T; Horstmann, MA; Imschweiler, T; Jorch, N; Pekrun, A; Schmid, I; Schramm, F; Spohn, M; Zimmermann, M; Zur Stadt, U | 1 |
Aotsuka, N; Doki, N; Fujisawa, S; Fujiwara, SI; Gotoh, M; Ishizaki, T; Kanamori, H; Kanda, J; Kanda, Y; Kimura, SI; Miyazaki, T; Mori, T; Najima, Y; Okamoto, S; Onizuka, M; Saito, T; Sakaida, E; Shono, K; Tachibana, T; Takahashi, S; Tanaka, M; Watanabe, R | 1 |
Absalon, MJ; Ahmed, A; August, K; Baker, SD; Boklan, J; Brown, PA; Cooper, TM; Gore, L; Li, L; Macy, ME; Magoon, D; Narendran, A; Pollard, J; Sison, EAR; Trippett, T | 1 |
Arai, Y; Atsuta, Y; Fukuda, T; Hoshino, T; Kawakita, T; Kondo, T; Mizuno, I; Mizuta, S; Mori, T; Ohashi, K; Onizuka, M; Ozawa, Y; Shigematsu, A; Tanaka, J; Ueda, Y; Yoshida, S | 1 |
Adams, M; Buck, G; Eiser, C; Goulden, N; Jenney, MEM; Mitchell, C; Stride, CB; Vora, A | 1 |
Cario, G; Conter, V; Dagdan, E; Hinze, L; Junk, S; Kratz, CP; Möricke, A; Schrappe, M; Stanulla, M; Zimmermann, M | 1 |
Arasteh, O; Hadjibabaie, M; Taghvaye Masoumi, H; Zarif-Yeganeh, M | 1 |
Alexander, PM; Caudell, DL; Kucera, GL; Pardee, TS; Pladna, KM | 1 |
Isaac McGraw, B; Savaşan, S; Sweeney, C | 1 |
Fang, B; Fu, Y; Liu, X; Song, Y; Wei, X; Yu, F; Zhang, Y; Zhou, H; Zhou, J; Zhou, K | 1 |
Alexander, TC; Allen, AR; Anderson, J; Carr, H; Carter, G; Groves, T; Kiffer, F; Simecka, CM; Wang, J | 1 |
Gong, B; Gong, X; Gu, R; Li, Y; Lin, D; Liu, B; Liu, K; Liu, Y; Mi, Y; Qiu, S; Wang, H; Wang, J; Wang, Y; Wei, H; Wei, S; Zhang, G; Zhao, X; Zhou, C | 1 |
Ming, Y; Pei, W; Si, S; Sun, L; Sun, Y; Wang, L; Zhang, K | 1 |
Bertrand, A; Cervos, M; Devaux, Y; Favier, B; Goy, F; Marcault-Derouard, A; Schell, M; Veyet, V | 1 |
Gul, A; Zafar, S | 1 |
Li, TT; Ma, JJ; Tao, SD; Yu, L; Zhang, L | 1 |
Fujimoto, J; Horibe, K; Sekimizu, M; Sunami, S; Takimoto, T; Tsurusawa, M | 1 |
Cardemil, D; Cartier R, L; Parra V, J; Puga, B | 1 |
Gökbuget, N; Wermann, WK | 1 |
Aymerich, M; Bataller, A; Camós, M; Colomer, D; Díaz-Beyá, M; Esteve, J; Garrote, M; López-Guerra, M; Oliver-Caldés, A; Vega-García, N | 1 |
Abe, M; Ando, N; Furuichi, Y; Goi, K; Harama, D; Inukai, T; Kagami, K; Kasai, S; Sugita, K; Tamai, M | 1 |
Abdalla, K; Abrar, MB; AlAzmi, AA; Elimam, N; Jastaniah, W; Mustafa, O | 1 |
Cao, Y; Hao, T; Hu, J; Huang, Q; Kang, Y; Lin, Z; Lu, P; Song, Y; Wu, C; Zhang, C; Zhu, X | 1 |
Chen, J; Ngo, D; Rosenthal, J | 1 |
Cheung, LC; Chua, GA; Cruickshank, MN; Ferrari, E; Ford, J; Hughes, AM; Kees, UR; Kotecha, RS; Lock, RB; Malinge, S; Oommen, J; Singh, S | 1 |
Madjidyar, J; Peters, S; Zhang, XD | 1 |
Geldenhuys, WJ; Gibson, LF; Martin, KH; Nair, RR; Piktel, D | 1 |
Baiocchi, RA; Dornbos, D; Elder, JB; Giglio, P; Otero, JJ; Puduvalli, VK; Slone, HW | 1 |
Arora, N; Gogoi, M; Islam, R; Krishnan, S; Kumar Mishra, D; Parihar, M; Roy, P; Saha, D; Saha, V | 1 |
Kantarjian, HM | 1 |
Cai, X; Chen, X; Li, C; Liang, Y; Wang, H; Xia, Z | 1 |
Alvaro, F; Bierings, MB; Cross, S; Dalla Pozza, L; de Bont, ES; de Groot-Kruseman, HA; de Haas, V; Haber, M; Hoogerbrugge, PM; Kaspers, GJ; Law, T; Maarten Egeler, R; Marshall, GM; Mueller, H; Ng, A; Norris, MD; Pieters, R; Révész, T; Suppiah, R; Sutton, R; van den Berg, H; van der Schoot, E; van der Velden, VH; van Dongen, J; Venn, NC | 1 |
Bernard, P; Eschard, C; Fichel, F; Grange, F; Munzer, M; Zachar, D | 1 |
Beato Merino, MJ; Gómez-Fernández, C; Hernández-Maraver, D; Herranz Pinto, P; Maldonado Cid, P; Noguera Morel, L; Sendagorta Cudós, E | 1 |
Boyerinas, B; Hyjek, EM; Price, TT; Sipkins, DA; Yesilkanal, AE; Zafrir, M | 1 |
Bisen-Hersh, EB; Hineline, PN; Walker, EA | 1 |
Cui, HX; Tang, XW; Wu, DP; Xue, MX; Xue, SL; Zhang, YM; Zou, JY | 1 |
Bartram, CR; Koehler, R | 1 |
Attarbaschi, A; Beier, R; Lauten, M; Möricke, A; Niggli, F; Odenwald, E; Schrappe, M; Stanulla, M; Zimmermann, M | 1 |
Conter, V; Gaynon, PS; Masera, G | 1 |
Beier, R; Cario, G; Debatin, KM; Gadner, H; Gruhn, B; Harbott, J; Henze, G; Klingebiel, T; Kremens, B; Ludwig, WD; Mann, G; Möricke, A; Niemeyer, C; Niggli, F; Ratei, R; Reiter, A; Ritter, J; Schrappe, M; Schrauder, A; Stanulla, M; Welte, K; Zimmermann, M | 1 |
Eckert, C; Henze, G; v Stackelberg, A | 1 |
Burger, JA; Challagundla, P; Champlin, RE; Cortes, JE; Estrov, Z; Faderl, S; Ferrajoli, A; Garris, R; Huang, X; Jorgensen, JL; Kantarjian, HM; Kebriaei, P; Luthra, R; O'Brien, S; Ravandi, F; Thomas, DA; Wang, SA; Wen, S | 1 |
Dzietczenia, J; Fornagiel, S; Jurczak, W; Kumiega, B; Skotnicki, AB | 1 |
Linkesch, W; Neumeister, P; Nösslinger, T; Pfeilstöcker, M; Troppan, K; Valentin, A | 1 |
Erdlenbruch, B; Güttel, C; Härtel, C; Lauten, M | 1 |
Hasegawa, D; Isoyama, K; Kajiwara, M; Kaneko, T; Kato, M; Kikuchi, A; Kinoshita, A; Koh, K; Maeda, M; Manabe, A; Ohara, A; Okimoto, Y; Saito, T; Sugita, K; Tsuchida, M | 1 |
Kato, K; Matsumoto, K; Matsuyama, T; Yoshida, N | 1 |
Ahlberg, L; Amini, RM; Åström, M; Bernell, P; Hägglund, H; Hallböök, H; Hulegårdh, E; Karlsson, K; Kozlowski, P; Markuszewska-Kuczymska, A; Smedmyr, B; Tomaszewska-Toporska, B | 1 |
Bonferroni, M; Borra, A; Castellino, C; Celeghini, I; Di Marco, C; Fiore, F; Gallamini, A; Ghiglia, A; Grasso, M; Marenchino, D; Mattei, D; Mordini, N; Rapezzi, D; Sorasio, R; Strola, G | 1 |
Asselin, BL; Bell, BA; Camitta, BM; Chauvenet, A; Devidas, M; Halperin, EC; Jones, TL; Kurtzberg, J; Pullen, J; Shuster, JJ; Tower, RL; Winick, N | 1 |
Baytan, B; Bengoa, SY; Evim, MS; Gözmen, S; Güneş, AM; Irken, G; Karapınar, TH; Oren, H; Tüfekçi, O | 1 |
Barisone, E; Berger, M; Cesaro, S; De Matteo, A; Locatelli, F; Menna, G; Messina, C; Micalizzi, C; Morello, W; Parasole, R; Pession, A; Petruzziello, F; Poggi, V; Testi, AM; Varotto, S | 1 |
Bolognia, J; Marks, P; Podoltsev, N; Zhang, B | 1 |
Goulden, N; Hancock, J; Hough, R; Mitchell, C; Moorman, AV; Rowntree, C; Vora, A; Wade, R | 1 |
Cai, YJ; Chen, GQ; Chen, J; Duan, CW; Enver, T; Hong, DL; Li, LH; Li, ZQ; Mi, JQ; Qin, X; Shi, J; Tao, Y; Wang, B; Yin, MZ; Yu, YH; Zhang, F; Zhou, XC | 1 |
Kline, RM; Simangan, LR | 1 |
Bacigalupo, A; Ballerini, F; Clavio, M; Cruciani, F; De Astis, E; Di Grazia, C; Galaverna, F; Ghiggi, C; Ghiso, A; Gobbi, M; Guolo, F; Lemoli, RM; Lovera, D; Marani, C; Miglino, M; Minetto, P; Mitscheunig, L; Pastori, G; Raiola, AM; Varaldo, R | 1 |
Borthakur, G; Cardenas-Turanzas, M; Cortes, JE; Daver, NG; Ferrajoli, A; Franklin, AR; Garcia-Manero, G; Garris, R; Jabbour, EJ; Jorgensen, JL; Kadia, TM; Kantarjian, HM; Konopleva, MY; Kornblau, SM; O'Brien, SM; Pemmaraju, N; Ravandi-Kashani, F; Rytting, ME; Schroeder, K; Thomas, DA | 1 |
Benton, CB; Borthakur, G; Dara, S; Franklin, AR; Garcia-Manero, G; Jabbour, E; Kantarjian, H; Kwari, M; O'Brien, S; Pierce, SR; Ravandi, F; Rytting, M; Thomas, DA; Yang, H | 1 |
Amrein, PC; Ballen, KK; Cohen, S; Couban, S; Dahlberg, SE; DeAngelo, DJ; Galinsky, I; Howson-Jan, K; Kelly, K; Leber, B; Matthews, JH; Neuberg, DS; Sallan, SE; Savoie, L; Seftel, MD; Silverman, LB; Sirulnik, LA; Stevenson, KE; Stone, RM; Supko, JG; Turner, AR; Wadleigh, M | 1 |
Kato, S; Konuma, T; Oiwa-Monna, M; Takahashi, S; Tojo, A | 1 |
Beitler de Mauriño, B; Dorlhiac-Llacer, PE; Martinez, GA; Medina, AB; Pinheiro Junior, ED; Pracchia, LF; Velloso, ED | 1 |
Ahn, JS; Chung, JS; Jo, DY; Joo, YD; Jung, SH; Kim, DY; Kim, I; Lee, JJ; Lee, KH; Moon, JH; Park, S; Shin, HJ; Sohn, SK; Song, IC; Yang, DH | 1 |
Boehm, I; Carol, H; Fan, MM; Harasym, TO; Houghton, P; Lock, RB; Mayer, LD; Smith, MA | 1 |
Akaihata, M; Hosoya, M; Ito, M; Kikuta, A; Kobayashi, S; Mochizuki, K; Ohara, Y; Sano, H; Waragai, T | 1 |
Koh, K | 1 |
Annesley, CE; Brown, P; Li, L; Magoon, D; Rau, RE; Sison, EA; Small, D | 1 |
Berube, C; Coutré, SE; Dinner, S; Dunn, T; Gotlib, J; Liedtke, M; Medeiros, B; Patel, S | 1 |
Akagi, T; Hofmann, WK; Jann, JC; Kato, M; Kawamata, N; Klaumünzer, M; Koeffler, HP; Liem, NL; Lock, RB; Marshall, GM; Mossner, M; Nowak, D; Nowak, V; Ogawa, S; Okamoto, R; Papa, RA; Sanada, M; Thoennissen, NH | 1 |
Kim, HJ; Kim, SH; Kim, W; Lee, SH; Park, BK; Park, HJ; Son, MH; Yoon, JH; Yoon, JY | 1 |
Chai, YH; Liang, Y; Pan, J; Pang, L; Wang, JR; Zhao, WL | 1 |
Bartyik, K; Bereczki, C; Berek, K; Endreffy, E; Erdelyi, DJ; Gabor, KM; Lautner-Csorba, O; Rarosi, F; Schermann, G; Semsei, AF; Szalai, C | 1 |
Bernstein, M; Krings, T; Kwan, BY; Mandell, DM | 1 |
Audemard, A; Bergot, E; Chantepie, S; de la Gastine, B; Gac, AC; Reman, O; Verger, H | 1 |
Jiao, W; Li, X; Liu, L; Qu, Q; Wu, D; Zhang, Y | 1 |
Cachia, D; Chi, L; Cortes, JE; Daver, N; Kamiya-Matsuoka, C; Kantarjian, HM; Pinnix, CC; Woodman, K | 1 |
Audisio, E; Bassan, R; Borlenghi, E; Cassibba, V; Cortelazzo, S; Cortelezzi, A; Corti, C; Fumagalli, M; Gallamini, A; Intermesoli, T; Marfisi, RM; Marmont, F; Masciulli, A; Mattei, D; Oldani, E; Parolini, M; Pogliani, EM; Rambaldi, A; Romani, C; Rossi, G; Scattolin, AM; Spinelli, O; Tosi, M | 1 |
Kang, HR; Kang, MG; Kim, JY; Lim, KH; Park, HK | 1 |
Arellano-Galindo, J; Bekker-Méndez, VC; Dueñas-González, MT; García-Jiménez, X; Jaimes-Reyes, EZ; Jiménez-Hernández, E; Marín-Palomares, T; Martínez Villegas, O; Mejía-Aranguré, JM; Ortíz-Fernández, A; Ortíz-Torres, MG; Sánchez-Jara, B; Tiznado-García, HM | 1 |
Blažek, B; Černá, Z; Domanský, J; Hak, J; Houdková, A; Hrušák, O; Jabali, Y; Janotová, I; Jarošová, M; Mejstříková, E; Mihál, V; Novák, Z; Procházková, D; Ptoszková, H; Sedláček, P; Smíšek, P; Starý, J; Štěrba, J; Timr, P; Trka, J; Zdráhalová, K; Zemanová, Z; Zuna, J | 1 |
Ding, C; Jiao, W; Li, X; Liu, L; Qu, Q; Wu, D; Zhang, Y | 1 |
Pieters, R; Schneider, P; Stam, RW; Stumpel, DJ | 1 |
Bae, SH; Chi, HS; Eom, HS; Hyun, MS; Jang, DY; Joo, YD; Jung, CW; Kim, DY; Kim, H; Kim, HJ; Kim, I; Kim, MK; Lee, GW; Lee, JH; Lee, KH; Lee, SM; Lee, WS; Lim, SN; Moon, JH; Park, S; Ryoo, HM; Shin, HJ; Sohn, SK; Won, JH; Yang, DH; Yun, SC | 1 |
Bierings, MB; de Vries, MC; Dekking, SA; Kodish, E; Lantos, JD; van Delden, JJ; van der Graaf, R | 1 |
Burger, JA; Champlin, R; Cortes, JE; Estrov, Z; Faderl, S; Ferrajoli, A; Garcia-Manero, G; Garris, R; Huang, X; Jabbour, E; Kantarjian, HM; Kebriaei, P; McCue, DA; O'Brien, SM; Ravandi, F; Rytting, ME; Thomas, DM; Verstovsek, S; Wierda, WG | 1 |
Carroll, WL; Devidas, M; Dupuis, LL; Hunger, SP; Kadan-Lottick, NS; Lu, X; Maloney, KW; Mattano, LA; Mitchell, HR; Sung, L; Winick, N | 1 |
Goto, H; Goto, S; Yokosuka, T | 1 |
Gao, J; Guo, J; Guo, X; Jia, CS; Li, Q; Zhou, CY; Zhu, YP | 1 |
Ashizawa, M; Fujiwara, S; Hatano, K; Ito, S; Kanda, Y; Kawasaki, Y; Mashima, K; Minakata, D; Muroi, K; Nakano, H; Oh, I; Ohmine, K; Okazuka, K; Sato, K; Sugimoto, M; Suzuki, T; Umino, K; Yamamoto, C; Yamasaki, R | 1 |
Ding, K; Geng, L; Liu, H; Qiang, P; Song, K; Sun, Z; Tang, B; Tong, J; Wang, X; Yao, W; Zhang, L; Zhang, X; Zheng, C; Zhu, X | 1 |
Afanasyev, B; Arcese, W; Bacigalupo, A; Beelen, D; Ciceri, F; Giebel, S; Gülbas, Z; Koc, Y; Labopin, M; Mohty, M; Nagler, A; Piemontese, S; Polge, E; Rubio, MT; Santarone, S; Savani, BN; Schmid, C; Tischer, J; Wu, D | 1 |
Fang, B; Huang, H; Lin, Q; Liu, L; Liu, Y; Song, Y; Yu, F; Zhang, Q | 1 |
Cortes, JE; Garcia-Manero, G; Garris, R; Issa, GC; Jabbour, E; Kantarjian, H; Luthra, R; O'Brien, SM; Patel, K; Ravandi, F; Sasaki, K; Short, NJ; Thomas, D | 1 |
Camós, M; Català, A; Caviedes-Cárdenas, L; Fernández-Calotti, P; Malatesta, R; Pastor-Anglada, M; Rives, S; Vega-García, N | 1 |
Abrahamsson, J; Åsberg, A; Grell, K; Harila-Saari, A; Heldrup, J; Jonsson, OG; Levinsen, M; Risteli, J; Schmiegelow, K; Taskinen, M; Vettenranta, K | 1 |
Baritussio, A; Bucciarelli-Ducci, C; Gately, A; Marks, DI; Pawade, J | 1 |
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Tomaszewska, B; Zoch-Zwierz, WM | 1 |
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Nishikawa, K | 1 |
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Borowitz, M; Bowman, WP; Buchanan, GR; Farrow, A; Jacaruso, D; Kamen, BA; Shuster, JJ; Winick, N | 1 |
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Buendia, MT; Lozano, JM; Terselich, G; Viscaino, MP | 1 |
Büchner, T; Hiddemann, W; Kern, W; Schleyer, E; Unterhalt, M; Wörmann, B | 1 |
Ahmed, T; Darzynkiewicz, Z; Feldman, EJ; Halicka, HD; Lake, D; Seiter, K; Traganos, F | 1 |
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Flexner, JM; Goodman, S; Greer, JP; Stein, RS; Wolff, SN | 1 |
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Hanada, R; Hongo, T; Horikoshi, Y; Sakurai, M; Yajima, S | 1 |
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Weiss, MA | 1 |
Balter, R; Degani, D; Franchini, M; Marradi, P; Meneghini, V; Perona, G; Ricetti, M; Tecchio, C; Todeschini, G; Zanotti, R | 1 |
Graham-Pole, J; Kumar, M; Meyers, L; Miller, A; Ochoa, S; Rao, PV; Saleh, A | 1 |
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Cohen, JD; Katz, TB; Marcel, PD; Strock, DJ; Teik, JE | 1 |
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Fujimoto, T | 1 |
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Avramis, VI; Dinndorf, PA; Kelleher, JF; Krailo, MD; Liu-Mares, W; Mosher, RB; Reaman, GH; Sato, JK; Seibel, NL; Wiersma, S | 1 |
Lennard, L; Lilleyman, JS; Welch, JC | 1 |
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Azuma, E; Higashigawa, M; Hirayama, M; Hori, H; Ido, M; Kawasaki, H; Sakurai, M | 1 |
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Donnelly, MJ; Gelber, RD; Gilliland, DG; McLean, TW; Sallan, SE; Silverman, LB; Tarbell, NJ | 1 |
Boyett, JM; Crom, WR; Evans, WE; Pui, CH; Relling, MV; Rodman, JH | 1 |
Feig, SA; Harris, RE; Sather, HN | 1 |
Can, E; Can, M; Gedikoğlu, G; Savaşan, S; Warrier, I | 1 |
Curtis, D; Fairley, C; Spelman, D; Szer, J; Ugoni, A; Vujovic, O; Woolley, I | 1 |
Avramis, VI; Kowck, R; Krailo, MD; Liu-Mares, W; Ramilo-Torno, LV; Reaman, GH; Sato, JK; Sharpe, A; Wiersma, S | 1 |
Lasorella, A; Mastrangelo, S; Riccardi, A; Riccardi, R; Servidei, T | 1 |
April, F; Meneghini, V; Perona, G; Pizzolo, G; Ricetti, MM; Solero, P; Tecchio, C; Todeschini, G; Veneri, D; Zanotti, R | 1 |
Goi, K; Iijima, K; Inukai, T; Kagami, K; Kinoshita, A; Kojika, S; Mori, T; Nakazawa, S; O-Koyama, T; Sugita, K; Suzuki, T; Tezuka, T | 1 |
Chavez, CM; Holdsworth, MT; Raisch, DW; Winter, SS | 1 |
Benet, L; Diaine, B; Mariani, R; Monpoux, F; Richelme, C; Sirvent, N | 1 |
Almici, C; Caramatti, C; Carlo-Stella, C; Mangoni, L; Rizzoli, V | 1 |
Amemiya, Y; Furukawa, Y; Hoshino, M; Imagawa, S; Izumi, T; Kawano, C; Kirito, K; Komatsu, N; Kuribara, R; Miura, Y; Miyazato, A; Muroi, K; Omine, K; Otsuki, T; Shimizu, R; Suzuki, T; Tabata, M; Takahashi, H; Takatoku, M; Terui, Y; Tomizuka, H; Toshima, M; Tsunoda, J; Uchida, M; Yoshida, M | 1 |
Chen, SH; Liang, DC; Liu, HC | 1 |
Apel, D; Maj, S; Mariańska, B; Seferyńska, I | 1 |
Drullinsky, P; Golde, DW; Maslak, P; Scheinberg, D; Weiss, MA | 1 |
Agaoglu, L; Anak, S; Aytepe, Z; Devecioglu, O; Gedikoglu, G; Guven, Y; Ozerkan, AG; Sepet, E; Yalman, N | 1 |
Behm, FG; Evans, WE; Hancock, ML; Head, DR; Kun, LE; Mahmoud, HH; Pui, CH; Relling, MV; Ribeiro, RC; Rivera, GK; Rubnitz, JE; Sandlund, JT | 1 |
Bailey, C; Burrett, J; Chessells, J; Hann, I; Hill, F; Richards, S | 1 |
Bruserud, O | 1 |
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den Boer, ML; Durian, M; Janka, G; Kaspers, GJ; Pieters, R; Schmiegelow, K; van Wering, ER; Veerman, AJ | 1 |
Archimbaud, E; Fiere, D; Thomas, X | 1 |
Borowitz, MJ; Camitta, B; Cheo, DL; Graham, ML; Harrison, MP; Kamen, BA; Land, VJ; Leventhal, BG; Pinkel, DP; Pullen, DJ; Shuster, JJ; Steuber, P; Whitehead, VM | 1 |
Aricò, M; Basso, G; Biondi, A; Conter, V; De Rossi, G; Di Tullio, MT; Lo Nigro, L; Masera, G; Messina, C; Miniero, R; Mori, PG; Pession, A; Rizzari, C; Rondelli, R; Santoro, N; Silvestri, D; Tamaro, P; Testi, A; Valsecchi, MG | 1 |
Anami, K; Asami, K; Chin, M; Fujimoto, T; Hatae, Y; Hirota, T; Horikoshi, Y; Ito, M; Iwai, A; Kaneko, Y; Katano, N; Kataoka, S; Kikuchi, M; Koizumi, S; Miyawaki, T; Mugisima, H; Nakayama, M; Nishikawa, K; Osima, K; Suzumiya, J; Taga, T; Tanaka, A; Tsurusawa, M; Watanabe, A; Yanase, T | 1 |
Kanamaru, A; Miyawaki, S; Mizoguchi, H; Nakamura, T; Ohashi, Y; Ohno, R; Tomonaga, M; Tsukagoshi, S; Yoshida, S | 1 |
Mauger, DC; Skeen, JE | 1 |
Deane, M; Foroni, L; Galactowicz, G; Hoffbrand, AV; Koh, M; Lawler, M; Prentice, HG; Secker-Walker, L | 1 |
Hiraoka, A; Kuraishi, Y; Ogawa, M; Okabe, K; Sampi, K; Takemoto, Y; Tamura, K | 1 |
Adamson, PC; Balis, FM; Gillespie, AJ; Moser, AM; Poplack, DG | 1 |
Belch, AR; Chlumecky, V; Gati, WP; Larratt, LM; Mant, MJ; Paterson, AR; Turner, AR | 1 |
Annino, L; Arcese, W; Giona, F; Mandelli, F; Meloni, G; Moleti, ML; Rondelli, R; Testi, AM | 1 |
Camera, A; Catalano, L; Picardi, M; Rotoli, B; Selleri, C | 1 |
Kaleita, TA; MacLean, WE; Reaman, GH; Sather, HN; Whitt, JK | 1 |
Kishimoto, Y; Kuraishi, Y; Masaoka, T; Mizoguchi, H; Ogawa, M; Okabe, K; Saito, H; Sampi, K; Takemoto, Y; Tamura, K | 1 |
Broekema, GJ; Duyn, AE; Hählen, K; Kaspers, GJ; Pieters, R; Van Zantwijk, CH; Veerman, AJ | 1 |
Hann, IM; McCarthy, AJ; Oakhill, A; Pitcher, LA | 1 |
Byrne, JL; Dasgupta, E; Forman, K; Haynes, AP; Mitchell, D; Pallis, M; Russell, NH; Turzanski, J | 1 |
Advis, P; Becker, A; Beresi, V; Cabrera, ME; Campbell, M; Paez, E; Quintana, J; Rojas, J; Salgado, C; Tapia, S; Vargas, L; Zolezzi, P | 1 |
Avigdor, A; Ben-Bassat, I; Ben-Yehuda, D; Berkowicz, M; Chetrit, A; Gillis, S; Hardan, I; Lossos, I; Raanani, P; Shpilberg, O; Sofer, O | 1 |
Gadner, H; Gaiger, A; Haas, OA; Heinze, G; Linnerth, B; Lion, T; Mann, G; Schmid, D; Tisljar, K | 1 |
Cortes, J; Fayad, L; Kantarjian, H; Keating, M; O'Brien, S | 1 |
Broekema, GJ; Haarman, EG; Hählen, K; Kaspers, GJ; Pieters, R; van Zantwijk, CH; Veerman, AJ | 1 |
Chimishkian, K; Gurova, K; Litvinova, E; Mentkevich, G | 1 |
Hongo, T; Horibe, K; Komada, Y; Matsuyama, T; Nishimura, Y; Sakurai, M; Takao, A | 1 |
Filatov, LB; Konstantinova, TS; Shalaev, VA | 1 |
Abramov, A; Attias, D; Ballin, A; Burstein, Y; Cividalli, G; Rechavi, G; Sharon, R; Stark, B; Sthoeger, D; Zaizov, R | 1 |
Bueno, J; Julià, A; Villalba, T; Zuazu, J | 1 |
Ozbek, N; Tuncer, AM; Yetgin, S | 1 |
Fasching, K; Gadner, H; Panzer, S; Panzer-Grümayer, ER; Schneider, M | 1 |
Boyett, JM; Buchanan, GR; Chauvenet, AR; Crist, WM; Maybee, DA; Pinkel, D; Pollock, BH; Rivera, GK; Wagner, H | 1 |
Eden, OB; Gibson, B; Hann, I; Hill, F; Kinsey, S; Lilleyman, J; Mitchell, C; Richards, S; Vora, A | 1 |
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Armata, J; Bogusławska-Jaworska, J; Bubała, H; Dłuzniewska, A; Kazanowska, B; Kowalczyk, J; Kołecki, P; Matysiak, M; Rokicka-Milewska, R; Sońta-Jakimczyk, D; Sopyło, B; Stańczak, E; Stefaniak, MJ; Stefańska, K; Wróbel, G | 1 |
Auclerc, MF; Auvrignon, A; Baruchel, A; Bauduer, F; Berthou, C; Bordigoni, P; Demeocq, F; Lamagnere, JP; Landman-Parker, J; Leblanc, T; Legall, E; Leverger, G; Mathey, C; Michel, G; Pautard, B; Perel, Y; Schaison, G; Schneider, P | 1 |
Appelbaum, FR; Boldt, DH; Head, DR; Karanes, C; Luthardt, FW; Norwood, T; Pugh, RP; Rankin, C; Rosen, PJ | 1 |
Feldman, EJ | 1 |
Darbyshire, PJ; Eden, OB; Harrison, G; Lawson, SE; Oakhill, A; Richards, S; Stevens, R | 1 |
Belasco, JB; Bunin, NJ; Lange, BJ; Leahey, AM; Meek, R; Scher, C | 1 |
Frost, BM; Gustafsson, G; Larsson, R; Lönnerholm, G; Nygren, P | 1 |
Cattaneo-Pangrazzi, RM; Eriksson, S; Fichtner, I; Horber, DH; Ludwig, PS; Schott, H; Schwendener, RA; von Ballmoos, P | 1 |
Molinari, A; Poletti, G; Poletti, V; Salvucci, M; Zaccaria, A; Zanchini, R; Zuffa, E | 1 |
Estlin, EJ; Hall, AG; Lowis, SP | 1 |
Adachi, Y; Iki, S; Kazama, K; Urabe, A; Usuki, K | 1 |
Lange, B | 1 |
Behm, FG; Boyett, JM; Campana, D; Coustan-Smith, E; Hancock, ML; Pui, CH; Raimondi, SC; Ribeiro, RC; Rivera, GK; Rubnitz, JE; Sancho, J; Sandlund, JT | 1 |
Huismans, DR; Pieters, R; Schuurhuis, GJ; Styczynski, J; Veerman, AJ; Wysocki, M | 1 |
Harila-Saari, A; Himanen, S; Lanning, M; Pääkkö, E; Pyhtinen, J; Vanionpää, L | 1 |
Balduzzi, A; Biagi, E; De Lorenzo, P; Rovelli, A; Tagliabue, A; Uderzo, C | 1 |
Horton, TM; Kaplan, SL; McClain, KL; Pease, CL | 1 |
Ma, Y; Qiao, Z; Yang, L | 1 |
Feng, S; Han, M; Li, C | 1 |
Bieri, S; Chapuis, B; Helg, C; Miralbell, R | 1 |
Weiss, M | 1 |
Ashihara, E; Fujita, N; Hatsuse, M; Inaba, T; Nakagawa, M; Ochiai, N; Okano, A; Shimazaki, C; Tsubakimoto, Y | 1 |
Behard, C; Benoit, Y; Boutard, P; Dastugue, N; Dresse, MF; Ferster, A; Lutz, P; Marguerite, G; Mazingue, F; Mechinaud, F; Millot, F; Norton, L; Otten, J; Philippe, N; Philippet, P; Plantaz, D; Plouvier, E; Rialland, X; Robert, A; Suciu, S; Thyss, A; Uyttebroeck, A; Vilmer, E; Waterkeyn, C | 1 |
Atra, A; Gerrard, M; Hann, IM; Hobson, R; Imeson, JD; Pinkerton, CR | 1 |
Eden, O; Gibson, B; Hann, I; Harrison, C; Harrison, G; Hill, F; Richards, S; Vora, A | 1 |
Akiyoshi, K; Eguchi, H; Hara, T; Inada, H; Ishii, E; Koga, H; Matsuzaki, A; Miyazaki, S; Nagatoshi, Y; Nakayama, H; Nibu, K; Okamura, J; Take, H; Tamai, Y; Yanai, F | 1 |
Fukumoto, Y; Kikawa, Y; Mayumi, M; Takeuchi, M; Tanizawa, A | 1 |
Biagi, E; Conter, V; Lazzareschi, I; Milani, M; Riccardi, R; Ruggiero, A; Sparano, P | 1 |
Auperin, A; Behrendt, H; Coze, C; Frappaz, D; Leverger, G; Lutz, P; Michon, J; Patte, C; Perel, Y; Raphaël, M; Terrier-Lacombe, MJ | 1 |
Kanda, Y; Mineishi, S; Murakami, J; Ogasawara, T; Saito, T; Seo, S; Shoji, N; Takaue, Y; Tanosaki, R; Tobinai, K | 1 |
Hohl, RJ; Holstein, SA | 1 |
Fletcher, BD; Harrison, PL; Kaste, SC; Kennedy, W; Neel, MD; Pui, CH; Razzouk, BI; Relling, MV; Ribeiro, RC; Rubnitz, JE; Sandlund, JT | 1 |
Bernard, M; Casassus, P; Delain, M; Desablens, B; Guilhot, F; Hunault-Berger, M; Ifrah, N; Jouet, JP; Milpied, N; Sadoun, A | 1 |
Catts, VS; Farnsworth, ML; Haber, M; Lock, RB; Lutze-Mann, LH; Norris, MD | 1 |
Ahmed, T; Feldman, EJ; Kancherla, R; Liu, D; Papageorgio, C; Pozzuoli, M; Seiter, K; Sreekantaiah, C; Weisberger, J; Weiss, M | 1 |
Barbui, T; Bassan, R; Borleri, G; Broccia, G; Casula, P; Corneo, G; Cortelezzi, A; Coser, P; Fabris, P; Izzi, T; Lambertenghi-Deliliers, G; Lerede, T; Morandi, S; Pogliani, E; Rambaldi, A; Rossi, G; Spedini, P; Vespignani, M | 1 |
Akiyoshi, K; Ayukawa, H; Eguchi, H; Ishii, E; Kamizono, J; Kawakami, K; Kinukawa, N; Koga, H; Kuroda, H; Matsuzaki, A; Okamura, J; Tamai, Y; Yanai, F | 1 |
Braess, J; Büchner, T; Hiddemann, W; Kern, W; Ohnesorge, J; Schleyer, E; Unterhalt, M; Wittmer, E; Wörmann, B | 1 |
Domracheva, EV; Gribanova, EO; Isaev, VG; Khoroshko, ND; Konstantinova, TS; Kucher, RA; Kulimova, EP; Lapin, VA; Maslova, ER; Miliutina, TI; Parovichnikova, EN; Pivnik, AV; Rekhtman, GB; Sarkisian, GP; Savchenko, VG; Sokolov, AN; Tikhonova, LIu; Ustinova, EN | 1 |
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Fortney, JE; Gibson, LF; Wenger, SL; Zhao, W | 1 |
Höllinger, P; Mattle, HP; Schroth, G; Zenhäusern, R | 1 |
Barcos, M; Bloomfield, CD; Freter, CE; Frizzera, G; Johnson, JL; Lee, EJ; Peterson, BA; Petroni, GR; Schiffer, CA | 1 |
Craddock, C; Garg, M; Lawler, M; Pawson, R; Potter, MN; Prentice, HG; Rassam, S; Rezvani, K; Theocharous, P; Yin, JA | 1 |
Anderson, SC; Baquis, GD; Jackson, A; Kirkwood, JR; Monteleone, P | 1 |
Creutzig, U; de Vries, E; Hählen, K; Huismans, DR; Janka-Schaub, GE; Jansen, G; Kaspers, GJ; Peters, GJ; Pieters, R; Rots, MG; van Zantwijk, CH; Veerman, AJ; Zwaan, CM | 1 |
Gadner, H; Grenzebach, J; Ludwig, WD; Parwaresch, R; Reiter, A; Riehm, H; Schrappe, M; Zimmermann, M | 1 |
Kopecna, L | 1 |
Haran, M; Klepfish, A; Lurie, Y; Malnick, S; Shtalrid, M | 1 |
Akabutu, JJ; Gati, WP; Grundy, PE; Paterson, AR; Sowa, B; Wright, AM | 1 |
Belden, CJ; Nelson, DA; Sherman, PM | 1 |
Estlin, EJ; Lowis, SP; Yule, SM | 1 |
Braine, H; Burke, PJ; Gore, SD; Jones, RJ; Karp, JE; Kaufmann, SH; Miller, CB; Piantadosi, S; Rowley, SD; Sotomayor, EM | 1 |
Gökbuget, N; Hoelzer, D | 1 |
Brinkman, J; Leen, R; Van Gennip, AH; Van Kuilenburg, AB; Verschuur, AC; Voûte, PA | 1 |
Deelman, BG; Kamps, WA; Kingma, A; Mooyaart, EL; Van Dommelen, RI; Wilmink, JT | 1 |
Kadan-Lottick, N; Neglia, JP | 1 |
Advani, SH; Banavali, SD; Bhatia, KG; Magrath, I; Naresh, KN; Soman, CS | 1 |
Cortes, J; Estrov, Z; Faderl, S; Giles, FJ; Huh, YO; Kantarjian, HM; O'Brien, S; Pierce, S; Ravandi, F; Thomas, D | 1 |
Damon, L; Linker, C; Navarro, W; Ries, C | 1 |
Armata, J; Boguslawska-Jaworska, J; Derwich, K; Juszczak, K; Klus, K; Kolecki, P; Kowalczyk, J; Krauze, A; Matysiak, M; Pawelec, K; Pisarek, J; Rokicka-Milewska, R; Skoczen, S; Sońta-Jakimczyk, D; Styczyński, J; Tomaszewska, R; Wisniewska-Slusarz, H; Wysocki, M; Łuszczynska, A | 1 |
Ansoborlo, S; Babin-Boilletot, A; Baruchel, A; Pacquement, H; Patte, C; Plouvier, E; Sakiroglu, C | 1 |
Aricò, M; Barisone, E; Basso, G; Conter, V; De Rossi, G; Locatelli, F; Masera, G; Messina, C; Micalizzi, MC; Pession, A; Poggi, V; Rizzari, C; Valsecchi, MG | 1 |
Jastrzebska, M; Lukowska, K; Pacholska, J; Paciorkiewicz, W; Rokicka-Milewska, R | 1 |
Humphries, JE; Lee, JT | 1 |
Jacobs, P; Wood, L | 1 |
Bajko, G; Drozdowska, D; Hansz, J; Woźny, T | 1 |
Abakumov, EM; Isaev, VG; Kucher, RA; Parovichnikova, EN; Savchenko, VG | 1 |
Amadori, S; Giona, F; Iori, AP; Mandelli, F; Meloni, G; Miniero, R; Moleti, ML; Pigna, M; Testi, AM | 1 |
Büchner, T; Hiddemann, W; Kewer, U; Reuter, C; Rolf, C; Schleyer, E; Uhrmeister, C; Unterhalt, M; Wörmann, B; Zühlsdorf, M | 1 |
Abakumov, EM; Isaev, VG; Khoroshko, ND; Navashin, SM; Savchenko, VG; Sokolov, AN; Turkina, AG; Viadro, MM | 1 |
Iwai, A; Komazawa, M; Maeda, H; Nagata, K; Ninomiya, T; Nishikawa, K; Ohmiya, A; Ohta, M; Sato, J; Tsuda, Y | 1 |
Amadori, S; Guglielmi, C; Mandelli, F; Martelli, M; Papa, G | 2 |
Sasaki, A; Tsukaguchi, M | 1 |
Yue, BB | 1 |
Forio, I; Giralt, J; Olive, T; Ortega, JJ; Salvador, L; Verges, R | 1 |
Di Mario, A; Etuk, B; Leone, G; Pagano, L; Salutari, P; Sica, S | 1 |
McCauley, DL | 1 |
Andrew, M; Barr, RD; Cairney, AE; DeVeber, LL; Halton, J; Pai, KM; Whitton, AC | 1 |
Schaison, GS | 1 |
Russell, S; Vowels, M | 1 |
Bosco, L; Bufton, MG; Faich, GA; Flynn, B; Gerstman, BB; Jolson, HM; Rinsler, SS; Simmons, WD; Stadel, BV; Williams, E | 1 |
Cersosimo, RJ | 1 |
Advani, SH; Gopal, R; Iyer, RS; Kurkure, PA; Nadkarni, KS; Nair, CN; Pai, SK; Pai, VR; Saikia, TK | 1 |
Flasshove, M; Höffken, K; Kellner, R; Schütte, HJ; Seeber, S | 1 |
Hoelzer, D | 1 |
Jiménez, E; Kohan, R; Pavlovsky, S; Rosso, A; Sackmann Muriel, F; Santarelli, MT; Svarch, E | 1 |
Annino, L; Camera, A; Ciolli, S; Deplano, W; Fabiano, F; Ferrara, F; Ladogana, S; Mandelli, F; Muti, G; Vegna, ML | 1 |
Andersen, JW; Bennett, JM; Cassileth, PA; Hoagland, HC; Mazza, JJ; O'Connell, MC; Paietta, E; Wiernik, P | 1 |
Amess, J; Bassan, R; Battista, R; Buelli, M; Carter, M; D'Emilio, A; Love, S; MacCallum, P; Rohatiner, AZ; Viero, P | 1 |
Andrien, JM; Bury, J; De Witte, T; Fillet, G; Hayat, M; Jaksic, B; Marie, JP; Muus, P; Peetermans, M; Stryckmans, P | 1 |
Alessandrino, EP; Bacigalupo, A; Bernasconi, C; Carella, AM; Ficarra, F; Lazzarino, M; Locatelli, F; Morra, E; Pagnucco, G; Resegotti, L | 1 |
Capalbo, S; Dione, R; Iacobazzi, A; Iaculli, ML; Liso, V; Pansini, N; Pavone, V; Specchia, G | 1 |
Grimfors, G; Järnmark, M; Lerner, R; Ljungman, P; Lönnqvist, B; Nyström-Rosander, C; Oberg, G; Palmblad, J; Samuelsson, J | 1 |
Akerman, S; Arlin, Z; Baskind, P; Budman, DR; DeAngelis, L; Feldman, EJ; Kreis, W; Lesser, M | 1 |
Langlands, K; Ludlam, CA; Parker, AC; Russell, L; Turner, ML; Watson, HG | 1 |
Benedetti-Panici, P; De Vincenzo, R; Iovino, MS; Leone, G; Macrì, E; Menichella, G; Piantelli, M; Pierelli, L; Scambia, G; Teofili, L | 1 |
De Vries, H; Haanen, C; Holtrop, M; Muus, P; Pennings, A; Van den Bogert, C | 1 |
Drigan, R; Gelber, RD; Spirito, A | 1 |
Horiuchi, A; Kageyama, T; Kakishita, E; Kanamaru, A; Kawagoe, H; Kitani, T; Masaoka, T; Nagai, K; Tatsumi, N; Yasunaga, K | 1 |
Diedrich, H; Freund, M; Ganser, A; Gramatzki, M; Haas, R; Heil, G; Henke, M; Heyll, A; Hiddemann, W; Kuse, R | 1 |
Bowman, WP; Buchanan, GR; Jacaruso, D; Kamen, BA; Roach, ES; Rollins, N; Winick, NJ | 1 |
Anaissie, E; Beran, M; Estey, EH; Gutterman, J; Kantarjian, HM; Keating, MJ; O'Brien, S; Rios, MB | 1 |
Baker, DK; McLeod, HL; Pui, CH; Rodman, JH | 1 |
Apel, D; Hołowiecki, J; Konecki, R; Lawniczek, T; Maj, S; Mariańska, B; Mazur, J; Pałynyczko, G; Rozmysłowicz, T; Rudzka, E | 1 |
Blattner, SR; Clavell, LA; Cohen, HJ; Donahue, K; Donnelly, M; Gelber, RD; Niemeyer, CM; Sallan, SE; Tarbell, NJ | 1 |
Holowiecki, J; Kachel, L; Lawniczek, T; Pajak, J; Rudzka, E | 1 |
Damon, LE; Linker, CA; Plunkett, W | 1 |
Ahmed, T; Arlin, ZA; Baskind, P; Chun, HG; Cook, P; Feldman, EJ; Marboe, C; Mehta, R; Mittelman, A; Puccio, C | 1 |
Annino, L; Arcese, W; Carotenuto, M; Giona, F; Iori, AP; Madon, E; Meloni, G; Resegotti, L; Testi, AM; Vegna, ML | 1 |
Ahmed, T; Arlin, ZA; Arnold, P; Baskind, P; Cook, P; Feldman, EJ; Finger, LR; Mittelman, A; Puccio, C; Razis, ED | 1 |
Cuttner, J; Davey, FR; Ellison, RR; Glicksman, AS; Henderson, ES; Mick, R; Royston, I; Schiffer, CA; Silver, RT; Woliver, T | 1 |
Crocker, I; Dabbs, CK; Kalin, NS; Lopez, PF; Sternberg, P; Vogler, WR | 1 |
Behrendt, H; Dufillot, D; Gentet, JC; Lamagnère, JP; Otten, J; Patte, C; Pein, F; Philip, T; Rodary, C; Zucker, JM | 1 |
Blattner, SR; Lynch, E; Schwenn, MR; Weinstein, HJ | 1 |
Brecher, M; Crist, W; Harris, MB; Krance, RA; Land, VJ; Newman, EM; Pullen, J; Ravindranath, Y; Shuster, JJ; Wimmer, R | 1 |
Antony, J; Bergin, M; Menser, MA; Procopis, PG; Shaw, PJ; Stevens, MM | 1 |
Beck, D; de Crousaz, H; Deonna, T; Janzer, RC; Miklossy, J; von der Weid, NX | 1 |
Benz-Lemoine, E; Bergerat, JP; Bordigoni, P; Cahn, JY; Colombat, P; Lutz, P; Pico, JL; Plouvier, E; Reiffers, J; Souillet, G | 1 |
Boyett, JM; Buchanan, GR; Crist, WM; Ghim, T; Johnson, W; Pollock, BH; Smith, SD; Vietti, TJ; Wharam, MD; Yanofsky, RA | 1 |
Frederick, E | 1 |
Kim, SH; Kondo, T; Nishimura, T; Okabe, T; Okazaki, K; Suzuki, H; Tanaka, N | 1 |
Amadori, S; Carella, AM; Carotenuto, M; Colella, R; Giona, F; Grotto, P; Leoni, P; Meloni, G; Resegotti, L; Testi, AM | 1 |
Brouwers, P; Poplack, D | 1 |
Essien, EM; Jeje, OM; Ogunsanwo, BA; Okpala, IE; Okunade, MA; Olatunji, PO; Shokunbi, WA | 1 |
Carden, PA; Ekert, H; Mitchell, SL; Tiedemann, K; Waters, KD | 1 |
Amess, J; Barbui, T; Barnett, MJ; Bassan, R; Battista, R; Gregory, W; Horton, M; Lim, J; Oza, A; Rohatiner, AZ | 2 |
De Boben, M; Diedrich, H; Freund, M; Ganser, A; Heil, G; Henke, M; Heyll, A; Hiddemann, W; Knauf, U; Koch, P | 1 |
Goebel, U; Graubner, U; Haas, RJ; Janka-Schaub, GE; Juergens, H; Spaar, HJ; Winkler, K | 1 |
Barlogie, B; Dicke, K; Estey, EH; Huh, YO; Kantarjian, HM; Keating, MJ; O'Brien, S; Smith, TL; Spinolo, J; Walters, RS | 1 |
Balter, R; Borgna-Pignatti, C; Caraballo, R; Colamaria, V; Dalla Bernardina, B; Marradi, P; Mazza, C; Procacci, C | 1 |
Bostrom, B; Haake, R; Kim, TH; Lasky, L; Nesbit, ME; Ramsay, NK; Uckun, F; Vallera, DA; Weisdorf, DJ; Woods, WG | 1 |
Bartsch, CH; Gadner, H; Martins da Cunha, AC | 1 |
Buchanan, G; Crist, W; Freeman, AI; Ochs, J; Pollock, BH; Rivera, GK | 1 |
Kaneko, Y; Kawai, S; Kondo, M; Mimaya, J; Tonouchi, T; Toyoda, Y; Ueda, R | 1 |
Harris, MB; Krance, RA; Newman, EM; Pinkel, D; Ravindranath, Y; Testi, AM; Villacorte, DG | 1 |
Belasco, JB; Luery, N; Scher, C | 1 |
Yao, EG; Zhang, RX | 1 |
Broekema, GJ; Dirven, MW; Hählen, K; Heyenbrok, MW; Huismans, DR; Loonen, AH; Pieters, R; Veerman, AJ | 1 |
Barnes, J; Eden, OB; Hann, IM; Pinkerton, CR | 1 |
Arning, M; Aul, C; Gehrt, A; Hadding, U; Runde, V; Schneider, W | 1 |
Estey, EH; Freireich, EJ; Kantarjian, HM; Keating, MJ; McCredie, KB; O'Brien, S; Schachner, J; Walters, RL | 1 |
Amara, F; Colonna, P | 1 |
Békássy, AN; Garwicz, S; Gulliksson, H; Liliemark, J; Peterson, C; Wiebe, T | 1 |
Gattringer, C; Konwalinka, G; Linkesch, W; Thaler, J | 1 |
Jacobs, P; Novitzky, N; Wood, L | 1 |
Atwood, J; Aur, RJ; Hanna, M; Sabbah, R; Sackey, K; Willoughby, S | 1 |
Andreeff, M; Hegewisch-Becker, S; Tafuri, A | 1 |
Cotes, PM; Hellebostad, M; Marstrander, J; Refsum, HE; Slørdahl, SH | 1 |
Bladé, J; Carreras, E; Cervantes, F; Grañena, A; Marín, P; Nomdedeu, B; Ribera, JM; Rozman, C; Sierra, J; Urbano-Ispizua, A | 1 |
Carcassonne, Y; Gastaut, JA; Launay, MC; Lejeune, C; Maraninchi, D; Richard, B; Sainty, D; Sebahoun, G; Tubiana, N | 1 |
Bader-Meunier, B; Dommergues, JP; Garel, D; Venencie, PY | 1 |
Hara, J; Inoue, M; Ishihara, S; Izumi, Y; Keisei, KH; Murayama, N; Okada, S; Osugi, Y; Tawa, A; Yagi, K | 1 |
Auzanneau, G; Gisselbrecht, C; Gratecos, N; Harousseau, JL; LeBlond, V; Michallet, M; Milpied, N; Sebban, C; Troussard, X; Witz, F | 1 |
Ito, T; Komatsu, M; Saito, Y; Takahashi, H; Toyota, T; Uzuka, Y | 1 |
Büchner, T; Diedrich, H; Donhuijsen-Ant, R; Gerith-Stolzenburg, S; Heil, G; Hiddemann, W; Ho, AD; Maschmeyer, G; Planker, M; Schumacher, K | 1 |
Avramis, VI; Holcenberg, JS; Mecum, RA; Nyce, J; Steele, DA | 1 |
Bender-Götze, C; Haas, RJ; Holler, E; Kolb, HJ; Thierfelder, S; Wilmanns, W | 1 |
Bordessoule, D; Brière, J; David, B; Desablens, B; Fière, D; Gorin, NC; Harousseau, JL; Hayat, M; Marty, M; Solal-Celigny, P | 1 |
Degos, JD; Malapert, D | 1 |
Bernard, P; Boiron, JM; Marit, G; Reiffers, J; Rice, A; Vezon, G | 1 |
Carella, AM; D'Amico, T; Damasio, E; Gaozza, E; Giordano, D; Nati, S; Piatti, G; Pungolino, E; Spriano, M | 1 |
Donnelly, JP; Muytjens, HL; Novakova, IR; Weers-Pothoff, G | 1 |
Akiyama, Y; Kiriyama, Y; Kitoh, T; Kubota, M; Mikawa, H; Takimoto, T; Tanizawa, A | 1 |
Fujimoto, T; Katano, N; Niwa, M; Tsurusawa, M | 1 |
Ihle, H; Ihle, R; Matthes, H | 1 |
Meyers, P; Redner, A; Steinherz, P; Tan, C; Wollner, N | 1 |
Ochs, JJ | 1 |
Dicke, KA; Spinolo, JA | 1 |
Forgeson, G; Gore, M; Goss, G; Lakhani, A; Maitland, J; Milan, S; Nandi, A; Perren, T; Powles, R; Treleaven, J | 1 |
Acebedo Lerzundi, G; Javier Manchón, G; Montagut Dueso, JM; Olivé Oliveras, T; Ortega Aramburu, JJ; Torán Fuentes, N | 1 |
Baba, Y; Fujieda, H; Hojo, H; Ohyashiki, JH; Ohyashiki, K; Toyama, K | 1 |
Annino, L; Avvisati, G; Carella, AM; Caronia, F; Carotenuto, M; Giona, F; Mandelli, F; Meloni, G; Petti, MC; Testi, AM | 1 |
Aherne, GW; Dawson, VM; Ford, J; Kees, UR; Piall, E | 1 |
Dybedal, I; Lamvik, J | 1 |
David, JC; Maniey, D; Marquet, J; Zittoun, J; Zittoun, R | 1 |
Castaman, G; Castronovo, S; Cortesi, S; Dini, E; Quaglio, R; Rodeghiero, F; Soffiati, G | 1 |
Bodensteiner, JB; Gay, CT; Nitschke, R; Sexauer, C; Wilson, D | 1 |
Cohen, G; Gitter, KA; Stewart, MW | 1 |
Caro, J; Erslev, AJ; Piroso, E | 1 |
Ablin, AR; Albo, VC; Bleyer, WA; Finklestein, JZ; Gaynon, PS; Grossman, NJ; Littman, PS; Novak, LT; Pyesmany, AF; Steinherz, PG | 1 |
Berry, D; Crist, W; Doering, E; Fernbach, D; Pullen, J; Shuster, J; van Eys, J; Wharam, M | 1 |
Mandelli, F; Petti, MC | 1 |
Onundarson, PT; Rowe, JM | 1 |
Camitta, B; Casper, J; Elfenbein, G; Graham-Pole, J; Gross, S; Herzig, R; Koch, P; Mahoney, D; Marcus, R; Munoz, L | 1 |
Arnet, B; Baumgartner, C; Beck, D; Berchtold, W; Bertrand, AM; Bleher, EA; Caflisch, U; Delaleu, B; Feldges, A; Stucki, F | 1 |
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Aarbakke, J; Kolmannskog, S; Moe, PJ; Prytz, PS; Slørdal, L | 1 |
Amadori, S; Bagnulo, S; Carli, M; Dini, G; Guazzelli, C; Mandelli, F; Masera, G; Rossi, MR; Zanesco, L; Zurlo, MG | 1 |
Hatae, Y; Hatayama, Y; Nakadate, H; Takeda, T | 1 |
Asano, Y; Hirota, Y; Miki, K; Morioka, E; Niho, Y; Ohhara, N; Ohtsuka, T; Shibuya, T; Taniguchi, S; Yamano, Y | 1 |
Killander, A; Simonsson, B; Smedmyr, B; Sundström, C | 1 |
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Boyett, J; Buchanan, GR; Murphy, SB; Winick, N; Yu, A | 1 |
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42 review(s) available for cytarabine and Acute Lymphoid Leukemia
Article | Year |
---|---|
Evolution and optimization of therapies for acute lymphoblastic leukemia in infants.
Topics: Child; Cytarabine; Hematopoietic Stem Cell Transplantation; Humans; Infant; Multicenter Studies as Topic; Myeloid-Lymphoid Leukemia Protein; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2023 |
Central Nervous System Prophylaxis and Treatment in Acute Leukemias.
Topics: Antineoplastic Combined Chemotherapy Protocols; Central Nervous System; Central Nervous System Neoplasms; Cytarabine; Humans; Leukemia, Myeloid, Acute; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2022 |
Venetoclax with CAG regimen for early T-cell precursor acute lymphoblastic leukemia: a case report and literature review.
Topics: Aclarubicin; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cells, T-Lymphoid; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma | 2023 |
[Current treatment of pediatric acute lymphoblastic leukemia].
Topics: Antineoplastic Combined Chemotherapy Protocols; Benzamides; Child, Preschool; Clinical Trials as Topic; Cytarabine; Dexamethasone; Drug Discovery; Humans; Imatinib Mesylate; Induction Chemotherapy; Mercaptopurine; Methotrexate; Molecular Targeted Therapy; Neoplasm, Residual; Piperazines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Pyrimidines | 2014 |
Clofarabine in pediatric acute leukemia: current findings and issues.
Topics: Adenine Nucleotides; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Child; Child, Preschool; Clinical Trials as Topic; Clofarabine; Cyclophosphamide; Cytarabine; Etoposide; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2012 |
[Experience with fludarabine treatment and review of the literature].
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Dexamethasone; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Immunophenotyping; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recombinant Proteins; Remission Induction; Treatment Outcome; Vidarabine | 2002 |
Recent advances in pediatric acute lymphoblastic and myeloid leukemia.
Topics: Acute Disease; Antineoplastic Agents; Biomarkers, Tumor; Child; Chromosome Aberrations; Clinical Trials as Topic; Cytarabine; Disease-Free Survival; Humans; Leukemia, Myeloid; Mitoxantrone; Neoplasm, Residual; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2003 |
Granular acute lymphoblastic leukemia: a case report and literature review.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Cytoplasmic Granules; Dexamethasone; Doxorubicin; Female; Humans; Immunophenotyping; Methotrexate; Middle Aged; Multiple Myeloma; Neoplasms, Second Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Treatment Outcome; Vincristine | 2007 |
Adult leukaemia in 1995: new directions.
Topics: Adult; Aged; Bone Marrow Transplantation; Child; Chromosomes, Human, Pair 22; Chromosomes, Human, Pair 9; Cytarabine; Humans; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Promyelocytic, Acute; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Translocation, Genetic; Tretinoin | 1995 |
A syndrome of lymphoblastic lymphoma, eosinophilia, and myeloid hyperplasia/malignancy associated with t(8;13)(p11;q11): description of a distinctive clinicopathologic entity.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transplantation; Carboplatin; Chromosomes, Human, Pair 13; Chromosomes, Human, Pair 8; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Eosinophilia; Etoposide; Fatal Outcome; Female; Humans; Hydroxyurea; Hyperplasia; Ifosfamide; Leukemia, Myeloid; Lymph Nodes; Male; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Pregnancy; Pregnancy Complications, Neoplastic; Remission Induction; Syndrome; Translocation, Genetic; Vincristine | 1995 |
rHuGM-CSF after high-dose chemotherapy in post-remission acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Etoposide; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recombinant Proteins | 1995 |
Central nervous system directed therapy in acute lymphoblastic leukaemia.
Topics: Adrenal Cortex Hormones; Adult; Child; Clinical Trials as Topic; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Female; Growth Disorders; Humans; Injections, Spinal; Leukemic Infiltration; Male; Meninges; Mental Disorders; Methotrexate; Neoplasms, Radiation-Induced; Neoplasms, Second Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Quality of Life; Radiation Injuries; Risk Factors; Survival Rate; Survivors; Treatment Outcome | 1994 |
Adult acute leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Burkitt Lymphoma; Clinical Trials as Topic; Combined Modality Therapy; Cytarabine; Humans; Leukemia-Lymphoma, Adult T-Cell; Methotrexate; Multicenter Studies as Topic; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Remission Induction; Survival Rate; Treatment Outcome | 1994 |
[Progress of chemotherapy in adult acute leukemia].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Disease-Free Survival; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Remission Induction; Survival Rate | 1995 |
Epipodophyllotoxins in the treatment of childhood cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Cytarabine; Etoposide; Humans; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Neoplasms; Neoplasms, Second Primary; Neuroblastoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Teniposide | 1994 |
Therapy for Philadelphia chromosome-positive acute lymphoblastic leukemia: possible use of interferon on the basis of some novel concepts.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Female; Gene Rearrangement; Genes, abl; Humans; Immunologic Factors; Interferon-alpha; Male; Mercaptopurine; Middle Aged; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction; Vincristine | 1993 |
Acute myelofibrosis terminating in acute lymphoblastic leukemia: case report and review of the literature.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Blast Crisis; Bone Marrow; Chromosome Deletion; Chromosomes, Human, Pair 5; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Cytarabine; Daunorubicin; Disease Progression; Flow Cytometry; Humans; Immunophenotyping; Male; Mercaptopurine; Methotrexate; Neoplastic Stem Cells; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Primary Myelofibrosis; Remission Induction; Vincristine | 1996 |
[Chemotherapy of relapsed AML and ALL].
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cytarabine; Etoposide; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Mechlorethamine; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prednisone; Procarbazine; Recurrence; Remission Induction; Vinblastine | 1996 |
[Polycythemia vera progressing to acute lymphoblastic leukemia after 13 years].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Middle Aged; Polycythemia Vera; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Time Factors; Vincristine | 1996 |
Treatment of adult patients with relapsed or refractory acute lymphoblastic leukemia (ALL).
Topics: Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction | 1997 |
[Recent advances on the treatment of acute childhood leukemia].
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Daunorubicin; Disease-Free Survival; Doxorubicin; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Remission Induction; Survival Rate; Treatment Outcome; Vincristine | 1997 |
Es nucleoside transporter content of acute leukemia cells: role in cell sensitivity to cytarabine (araC).
Topics: Acute Disease; Antimetabolites, Antineoplastic; Carrier Proteins; Cytarabine; Drug Resistance, Neoplasm; Flow Cytometry; Fluoresceins; Gene Expression; Humans; Leukemia, Myeloid, Acute; Lymphocytes; Membrane Proteins; Microscopy, Confocal; Nucleoside Transport Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Purine Nucleosides | 1998 |
Optimizing antimetabolite-based chemotherapy for the treatment of childhood acute lymphoblastic leukaemia.
Topics: Antimetabolites, Antineoplastic; Child; Cytarabine; Drug Administration Schedule; Etoposide; Humans; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Teniposide; Thioguanine | 2000 |
The management of neoplastic disorders of haematopoiesis in children with Down's syndrome.
Topics: Acute Disease; Adolescent; Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cytarabine; Daunorubicin; Disease-Free Survival; Down Syndrome; Female; Genetic Predisposition to Disease; Humans; Infant; Infant, Newborn; Leukemia; Leukemia, Myeloid; Male; Maternal Age; Myeloproliferative Disorders; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Vincristine | 2000 |
Induction therapy of adult acute lymphocytic leukemia without the use of vincristine or prednisone.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Controlled Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Dactinomycin; Doxorubicin; Etoposide; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Humans; Male; Mercaptopurine; Methotrexate; Middle Aged; Mitoxantrone; Multicenter Studies as Topic; Neutropenia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prospective Studies; Randomized Controlled Trials as Topic; Recombinant Proteins; Remission Induction; Survival Analysis; Treatment Outcome; Vincristine | 2001 |
Long-term outcome of treatment with protocols AL841, AL851, and ALHR88 in children with acute lymphoblastic leukemia: results obtained by the Kyushu-Yamaguchi Children's Cancer Study Group.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Body Height; Body Weight; Child; Child, Preschool; Clinical Trials as Topic; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Growth Disorders; Heart Failure; Hematopoietic Stem Cell Transplantation; Humans; Infant; Japan; Male; Methotrexate; Myelodysplastic Syndromes; Neoplasms, Second Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction; Retrospective Studies; Salvage Therapy; Survival Rate; Survivors; Treatment Outcome; Vincristine | 2001 |
[Skin toxicity associated with bolus infusion of low-dose cytarabine].
Topics: Antimetabolites, Antineoplastic; Child, Preschool; Cytarabine; Drug Eruptions; Humans; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2001 |
Intrathecal chemotherapy with antineoplastic agents in children.
Topics: Adrenal Cortex Hormones; Antineoplastic Agents; Blood-Brain Barrier; Cerebellar Neoplasms; Cerebrospinal Fluid; Child; Cytarabine; Humans; Injections, Spinal; Lymphoma; Medulloblastoma; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Thiotepa | 2001 |
Secondary acute myelogenous leukemia and myelodysplasia without abnormalities of chromosome 11q23 following treatment of acute leukemia with topoisomerase II-based chemotherapy.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosomes, Human, Pair 11; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cytarabine; Disease Progression; Disease-Free Survival; Enzyme Inhibitors; Etoposide; Female; Humans; Idarubicin; Incidence; Karyotyping; Leukemia, Myeloid; Life Tables; Male; Middle Aged; Mitoxantrone; Myelodysplastic Syndromes; Neoplasm Proteins; Neoplasms, Second Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Randomized Controlled Trials as Topic; Remission Induction; Retrospective Studies; Topoisomerase II Inhibitors; Treatment Outcome; Tretinoin | 2001 |
Brief-duration high-intensity chemotherapy for patients with small noncleaved-cell lymphoma or FAB L3 acute lymphocytic leukemia: results of cancer and leukemia group B study 9251.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System; Cyclophosphamide; Cytarabine; Drug Administration Schedule; Etoposide; Female; Humans; Ifosfamide; Infections; Injections, Spinal; Lymphoma, Non-Hodgkin; Male; Methotrexate; Neutropenia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Survival Analysis; Thrombocytopenia; Vincristine | 2001 |
Consolidation therapy for childhood acute lymphoblastic leukaemia: clinical and cellular pharmacology of cytosine arabinoside, epipodophyllotoxins and cyclophosphamide.
Topics: Antineoplastic Agents; Child; Cyclophosphamide; Cytarabine; Humans; Podophyllotoxin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction | 2001 |
Aggressive chemotherapy for acute leukemia relapsed after bone marrow transplantation: a second chance?
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Chemotherapy, Adjuvant; Cytarabine; Daunorubicin; Humans; Idarubicin; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Recurrence; Time Factors; Vincristine | 1992 |
Treatment of adult acute leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prevalence; Prognosis; Remission Induction; United States | 1992 |
[Role of bone marrow graft in the treatment of acute lymphoblastic leukemias in children].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Female; Graft vs Host Reaction; HLA Antigens; Humans; Infant; Male; Melphalan; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Transplantation, Autologous; Transplantation, Homologous | 1992 |
Idarubicin: an anthracycline antineoplastic agent.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biological Availability; Breast Neoplasms; Cytarabine; Drug Labeling; Humans; Idarubicin; Leukemia, Myeloid, Acute; Lung Neoplasms; Lymphoma; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1992 |
Acute fatal myeloencephalopathy after combined intrathecal chemotherapy in a child with acute lymphoblastic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Diseases; Child; Coma; Cytarabine; Female; Humans; Injections, Spinal; Methotrexate; Neoplasm Recurrence, Local; Paralysis; Paraplegia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Spinal Cord Diseases | 1991 |
Transient focal leukoencephalopathy following intraventricular methotrexate and cytarabine. A complication of the Ommaya reservoir: case report and review of the literature.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Diseases; Cytarabine; Humans; Infusions, Parenteral; Magnetic Resonance Imaging; Male; Meningeal Neoplasms; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1990 |
[Painful legs and moving toes. Neuropathy caused by cytarabine].
Topics: Adolescent; Axons; Carbamazepine; Cytarabine; Dose-Response Relationship, Drug; Humans; Leg; Male; Movement Disorders; Pain; Peripheral Nervous System Diseases; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Reflex, Abnormal; Sensory Receptor Cells; Syndrome; Toes | 1989 |
Neurotoxicity due to central nervous system therapy for childhood leukemia.
Topics: Central Nervous System; Child; Cytarabine; Humans; Meningeal Neoplasms; Methotrexate; Neurosecretory Systems; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1989 |
High dose therapy and autologous bone marrow transplant (ABMT) in acute leukemia: is purging necessary?
Topics: Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Humans; Leukemia, Myeloid, Acute; Neoplastic Stem Cells; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Preoperative Care; Transplantation, Autologous; Whole-Body Irradiation | 1989 |
[Intensification of the initial treatment in acute lymphoblastic leukemias of middle and high risk in children].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child; Child, Preschool; Cytarabine; Female; Humans; Infant; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Risk Factors | 1989 |
[Transient hypofibrinogenemia induced by prednisolone in a case of acute lymphoblastic leukemia].
Topics: Afibrinogenemia; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Mercaptopurine; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Vincristine | 1989 |
238 trial(s) available for cytarabine and Acute Lymphoid Leukemia
Article | Year |
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Chemotherapy intravenously in children with cancer at home, the nurse practitioner makes it possible!
Topics: Administration, Intravenous; Antimetabolites, Antineoplastic; Child; Child, Preschool; Cytarabine; Female; Home Care Services; Humans; Male; Methotrexate; Netherlands; Nurse Practitioners; Pilot Projects; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Quality of Life | 2019 |
Randomized post-induction and delayed intensification therapy in high-risk pediatric acute lymphoblastic leukemia: long-term results of the international AIEOP-BFM ALL 2000 trial.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Infant; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Time; Treatment Outcome; Vincristine | 2020 |
Adolescent and young adult acute lymphoblastic leukemia. Final results of the phase II pediatric-like GIMEMA LAL-1308 trial.
Topics: Adolescent; Adult; Allografts; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Cytarabine; Dexamethasone; Disease-Free Survival; Doxorubicin; Female; Hematopoietic Stem Cell Transplantation; Humans; Italy; Kaplan-Meier Estimate; Male; Mercaptopurine; Methotrexate; Neoplasm, Residual; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Treatment Outcome; Vincristine; Young Adult | 2021 |
Clofarabine increases the eradication of minimal residual disease of primary B-precursor acute lymphoblastic leukemia compared to high-dose cytarabine without improvement of outcome. Results from the randomized clinical trial 08-09 of the Cooperative Acut
Topics: Acute Disease; Antineoplastic Agents; Child; Clofarabine; Cytarabine; Disease-Free Survival; Humans; Lymphoma, Non-Hodgkin; Neoplasm, Residual; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome | 2022 |
A phase 1 study of the CXCR4 antagonist plerixafor in combination with high-dose cytarabine and etoposide in children with relapsed or refractory acute leukemias or myelodysplastic syndrome: A Pediatric Oncology Experimental Therapeutics Investigators' Co
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Benzylamines; Child; Child, Preschool; Cyclams; Cytarabine; Etoposide; Female; Heterocyclic Compounds; Humans; Leukemia, Myeloid, Acute; Male; Myelodysplastic Syndromes; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, CXCR4; Treatment Outcome; Young Adult | 2017 |
Prospective evaluation of quality of life in children treated in UKALL 2003 for acute lymphoblastic leukaemia: A cohort study.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Consolidation Chemotherapy; Cyclophosphamide; Cytarabine; Doxorubicin; Female; Follow-Up Studies; Humans; Infant; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Prospective Studies; Quality of Life; Surveys and Questionnaires; Young Adult | 2017 |
Phase II Clinical Trial for Newly Diagnosed Children and Adolescents with Localized Lymphoblastic Lymphoma (Japanese Leukemia/Lymphoma Study Group Trial LLB-NHL03) : Study Protocol for Nationwide Multicenter Trial.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Clinical Trials, Phase II as Topic; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Humans; Multicenter Studies as Topic; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Thioguanine; Vincristine | 2018 |
High-risk childhood acute lymphoblastic leukemia in first remission treated with novel intensive chemotherapy and allogeneic transplantation.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Hematopoietic Stem Cell Transplantation; Humans; Infant; Kaplan-Meier Estimate; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prospective Studies; Remission Induction; Risk Factors; Transplantation, Homologous; Treatment Outcome; Vincristine | 2013 |
[Molecular genetic detection of minimal residual disease (MRD) in children with acute lymphoblastic leukemia].
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Genetic Markers; Humans; Mercaptopurine; Methotrexate; Neoplasm, Residual; Polymerase Chain Reaction; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Prospective Studies; Vincristine | 2013 |
Prediction of outcome by early response in childhood acute lymphoblastic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Biopsy; Bone Marrow; Cell Lineage; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Infant; Kaplan-Meier Estimate; Male; Mercaptopurine; Methotrexate; Patient Outcome Assessment; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Prospective Studies; Remission Induction; Risk Assessment; Vincristine | 2013 |
No impact of high-dose cytarabine and asparaginase as early intensification with intermediate-risk paediatric acute lymphoblastic leukaemia: results of randomized trial TCCSG study L99-15.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Infant; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Risk Factors; Survival Rate; Treatment Outcome | 2014 |
Peripheral blood CD34+ percentage at hematological recovery after chemotherapy is a good early predictor of harvest: a single-center experience.
Topics: Adolescent; Adult; Aged; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Benzylamines; Biomarkers; Cyclams; Cyclophosphamide; Cytarabine; Drug Administration Schedule; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Heterocyclic Compounds; Hodgkin Disease; Humans; Leukocyte Count; Lymphoma, Non-Hodgkin; Male; Middle Aged; Peripheral Blood Stem Cell Transplantation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Time Factors; Transplantation, Autologous | 2014 |
Dose intensification of methotrexate and cytarabine during intensified continuation chemotherapy for high-risk B-precursor acute lymphoblastic leukemia: POG 9406: a report from the Children's Oncology Group.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Cytarabine; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Remission Induction; Risk Factors; Survival Rate; Teniposide | 2014 |
Augmented post-remission therapy for a minimal residual disease-defined high-risk subgroup of children and young people with clinical standard-risk and intermediate-risk acute lymphoblastic leukaemia (UKALL 2003): a randomised controlled trial.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Consolidation Chemotherapy; Cyclophosphamide; Cytarabine; Dexamethasone; Disease-Free Survival; Doxorubicin; Drug Hypersensitivity; Female; Follow-Up Studies; Humans; Infant; Male; Mercaptopurine; Methotrexate; Mucositis; Neoplasm, Residual; Pancreatitis; Polyethylene Glycols; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Risk Assessment; Stomatitis; Survival Rate; Vincristine | 2014 |
Safety and clinical activity of 5-aza-2'-deoxycytidine (decitabine) with or without Hyper-CVAD in relapsed/refractory acute lymphocytic leukaemia.
Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bone Marrow; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Decitabine; Dexamethasone; DNA Methylation; DNA, Neoplasm; Doxorubicin; Drug Administration Schedule; Female; Gastrointestinal Diseases; Humans; Hyperglycemia; Infusions, Intravenous; Kaplan-Meier Estimate; Male; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Salvage Therapy; Vincristine; Young Adult | 2014 |
Long-term outcome of a pediatric-inspired regimen used for adults aged 18-50 years with newly diagnosed acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cytarabine; Doxorubicin; Drug Administration Schedule; Female; Humans; Karyotyping; Male; Methotrexate; Middle Aged; Precision Medicine; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Survival Analysis; Treatment Outcome; Vincristine | 2015 |
Salvage therapy with mitoxantrone, etoposide and cytarabine in relapsed or refractory acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Follow-Up Studies; Humans; Male; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Retrospective Studies; Salvage Therapy | 2014 |
Randomized trial of radiation-free central nervous system prophylaxis comparing intrathecal triple therapy with liposomal cytarabine in acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Injections, Spinal; Liposomes; Male; Middle Aged; Pilot Projects; Post-Exposure Prophylaxis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Young Adult | 2015 |
[The prospects for children with acute lymphoblastic leukemia of being cured has increased in the Czech Republic in the 21st century to 90% - outcome of the ALL-IC BFM 2002 trial].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Czech Republic; Daunorubicin; Dexamethasone; Doxorubicin; Female; Humans; Infant; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Survival Rate; Thioguanine; Vincristine | 2015 |
Long-term follow-up of imatinib plus combination chemotherapy in patients with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Etoposide; Female; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Humans; Imatinib Mesylate; Induction Chemotherapy; Male; Methotrexate; Middle Aged; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Recurrence; Remission Induction; Survival Analysis; Transplantation, Homologous; Vincristine | 2015 |
Long-term follow-up of a phase 2 study of chemotherapy plus dasatinib for the initial treatment of patients with Philadelphia chromosome-positive acute lymphoblastic leukemia.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Dasatinib; Dexamethasone; Doxorubicin; Female; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Neoplasm, Residual; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Survival Analysis; Treatment Outcome; Vincristine; Young Adult | 2015 |
Anxiety, pain, and nausea during the treatment of standard-risk childhood acute lymphoblastic leukemia: A prospective, longitudinal study from the Children's Oncology Group.
Topics: Antineoplastic Combined Chemotherapy Protocols; Anxiety; Asparaginase; Child; Child, Preschool; Consolidation Chemotherapy; Cyclophosphamide; Cytarabine; Dexamethasone; Female; Humans; Induction Chemotherapy; Longitudinal Studies; Maintenance Chemotherapy; Male; Mercaptopurine; Methotrexate; Nausea; Pain; Parents; Polyethylene Glycols; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Surveys and Questionnaires; Vincristine | 2016 |
Efficacy and Toxicity of Intrathecal Liposomal Cytarabine in First-line Therapy of Childhood Acute Lymphoblastic Leukemia.
Topics: Adolescent; Child; Child, Preschool; Cytarabine; Dexamethasone; Disease-Free Survival; Female; Humans; Infant; Injections, Spinal; Liposomes; Maintenance Chemotherapy; Male; Neurotoxicity Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Scandinavian and Nordic Countries | 2016 |
High hyperdiploid acute lymphoblastic leukemia (ALL)-A 25-year population-based survey of the Austrian ALL-BFM (Berlin-Frankfurt-Münster) Study Group.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Chromosomes, Human, Pair 17; Cyclophosphamide; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Male; Mercaptopurine; Methotrexate; Mosaicism; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Retrospective Studies; Survival Rate; Time Factors; Trisomy; Vincristine | 2017 |
Neurocognitive outcomes among children who experienced seizures during treatment for acute lymphoblastic leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cognition Disorders; Cytarabine; Dexamethasone; Female; Humans; Hydrocortisone; Incidence; Leukoencephalopathies; Magnetic Resonance Imaging; Male; Mercaptopurine; Methotrexate; Neuropsychological Tests; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Risk Factors; Seizures; Vincristine | 2017 |
Reinduction platform for children with first marrow relapse of acute lymphoblastic Leukemia: A Children's Oncology Group Study[corrected].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Neoplasms; Central Nervous System Neoplasms; Child; Child, Preschool; Cytarabine; Dexamethasone; Doxorubicin; Female; Flow Cytometry; Humans; Idarubicin; Infant; Leukemia, T-Cell; Leukemic Infiltration; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction | 2008 |
Minimal residual disease is an important predictive factor of outcome in children with relapsed 'high-risk' acute lymphoblastic leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Hematopoietic Stem Cell Transplantation; Humans; Infant; Male; Mercaptopurine; Methotrexate; Multivariate Analysis; Neoplasm, Residual; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Predictive Value of Tests; Prednisone; Prognosis; Prospective Studies; Recurrence; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; Survival Analysis; Treatment Outcome; Vincristine | 2008 |
Effective combination treatment of advanced acute lymphocytic leukemia with cytosine arabinoside (NSC-63878) and L-asparaginase (NSC-109229).
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cytarabine; Female; Humans; Infant; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Treatment Outcome | 1972 |
Liposomal cytarabine in advanced-stage acute lymphoblastic leukemia and aggressive lymphoma with central nervous system involvement: experience of the Polish Acute Leukemia Group.
Topics: Adolescent; Adult; Aged; Central Nervous System Neoplasms; Cytarabine; Drug Carriers; Female; Humans; Liposomes; Lymphoma; Male; Middle Aged; Poland; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Treatment Outcome; Young Adult | 2009 |
[IDA-FLAG regimen in treatment of patients with refractory or relapsed acute leukemia].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Vidarabine | 2009 |
Fludarabine, amsacrine, high-dose cytarabine and 12 Gy total body irradiation followed by allogeneic hematopoietic stem cell transplantation is effective in patients with relapsed or high-risk acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Humans; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Risk Factors; Survival Rate; Transplantation Conditioning; Transplantation, Homologous; Vidarabine; Whole-Body Irradiation | 2009 |
DV-ICE, intensive induction and early transplantation for adult patients with acute lymphoblastic leukemia: a phase II study.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Dexamethasone; Disease-Free Survival; Early Termination of Clinical Trials; Etoposide; Female; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Humans; Hydrocortisone; Idarubicin; Kaplan-Meier Estimate; Male; Methotrexate; Middle Aged; Pilot Projects; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Treatment Failure; Vincristine; Young Adult | 2009 |
Comparison of neurocognitive functioning in children previously randomly assigned to intrathecal methotrexate compared with triple intrathecal therapy for the treatment of childhood acute lymphoblastic leukemia.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Attention; Child; Child, Preschool; Cognition; Cross-Sectional Studies; Cytarabine; Female; Humans; Hydrocortisone; Infant; Injections, Spinal; Intelligence Tests; Linear Models; Male; Memory; Methotrexate; Neuropsychological Tests; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Psychomotor Performance; Time Factors; Treatment Outcome; United States | 2009 |
[Effectiveness of remission induction with high-dose cytarabine for relapsed or refractory pediatric acute leukemia].
Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Child, Preschool; Cytarabine; Female; Humans; Infant; Invasive Pulmonary Aspergillosis; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pulse Therapy, Drug; Recurrence; Remission Induction; Treatment Outcome | 2010 |
Long-term outcome in children with relapsed acute lymphoblastic leukemia after time-point and site-of-relapse stratification and intensified short-course multidrug chemotherapy: results of trial ALL-REZ BFM 90.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Chi-Square Distribution; Child; Child, Preschool; Cranial Irradiation; Cytarabine; Disease-Free Survival; Drug Administration Schedule; Etoposide; Europe; Female; Humans; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proportional Hazards Models; Radiotherapy, Adjuvant; Recurrence; Risk Assessment; Risk Factors; Stem Cell Transplantation; Time Factors; Treatment Outcome | 2010 |
Simultaneous detection of MDR1 and WT1 gene expression to predict the prognosis of adult acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biomarkers, Tumor; Bone Marrow; Cohort Studies; Cyclophosphamide; Cytarabine; Dexamethasone; Disease-Free Survival; Doxorubicin; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Leukemic; Genes, Wilms Tumor; Humans; Male; Methotrexate; Middle Aged; Neoplasm Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Remission Induction; RNA, Messenger; RNA, Neoplasm; Vincristine; WT1 Proteins; Young Adult | 2010 |
Effect of genetic alterations of cytarabine- metabolizing enzymes in childhood acute lymphoblastic leukemia.
Topics: Adolescent; Alleles; Antigens, CD19; Antimetabolites, Antineoplastic; Child; Child, Preschool; Cytarabine; Cytidine Deaminase; Deoxycytidine Kinase; Dose-Response Relationship, Drug; Female; Flow Cytometry; Gene Frequency; Genotype; Humans; Infant; Leukocyte Common Antigens; Male; Mucositis; Neoplasm Staging; Neoplasm, Residual; Polymorphism, Single Nucleotide; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Thrombocytopenia; Treatment Outcome | 2010 |
Liposomal cytarabine is effective and tolerable in the treatment of central nervous system relapse of acute lymphoblastic leukemia and very aggressive lymphoma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Burkitt Lymphoma; Central Nervous System Neoplasms; Cytarabine; Female; Humans; International Agencies; Liposomes; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Risk Factors; Survival Rate; Treatment Outcome; Young Adult | 2011 |
Southwest Oncology Group Study S0530: a phase 2 trial of clofarabine and cytarabine for relapsed or refractory acute lymphocytic leukaemia.
Topics: Adenine Nucleotides; Adult; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Connective Tissue Growth Factor; Cytarabine; Female; Humans; Male; Neoplasm Proteins; Nucleoside Transport Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Recurrence; Treatment Outcome | 2010 |
Effect of mitoxantrone on outcome of children with first relapse of acute lymphoblastic leukaemia (ALL R3): an open-label randomised trial.
Topics: Adolescent; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Dexamethasone; Disease-Free Survival; Etoposide; Female; Humans; Idarubicin; Infant; Kaplan-Meier Estimate; Leukocyte Count; Male; Mercaptopurine; Methotrexate; Mitoxantrone; Polyethylene Glycols; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Risk Assessment; Treatment Outcome; United Kingdom; Vidarabine; Vincristine | 2010 |
The utility of performing the initial lumbar puncture on day 8 in remission induction therapy for childhood acute lymphoblastic leukemia: TCCSG L99-15 study.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Case-Control Studies; Central Nervous System Neoplasms; Child; Child, Preschool; Cohort Studies; Cytarabine; Female; Humans; Infant; Injections, Spinal; Male; Methotrexate; Neoplasm Recurrence, Local; Netherlands; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prospective Studies; Remission Induction; Spinal Puncture; Survival Rate; Time Factors; Treatment Outcome | 2012 |
[Long-term observations of children with acute lymphoblastic leukemia and high leukocytosis treated according to modified "New York" protocols (1987-2003)].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Comorbidity; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Infant; Leukocytosis; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Survival Rate; Thioguanine; Vincristine | 2010 |
Augmented therapy improves outcome for pediatric high risk acute lymphocytic leukemia: results of Children's Oncology Group trial P9906.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Female; Humans; Infant; Kaplan-Meier Estimate; Male; Mercaptopurine; Methotrexate; Neoplasm, Residual; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Risk Factors; Thioguanine; Treatment Outcome; Vincristine | 2011 |
Efficacy of an intensive post-induction chemotherapy regimen for adult patients with Philadelphia chromosome-negative acute lymphoblastic leukemia, given predominantly in the out-patient setting.
Topics: Adolescent; Adult; Aged; Ambulatory Care Facilities; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Germany; Humans; Male; Middle Aged; Outpatients; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Treatment Outcome; Young Adult | 2011 |
Dose intensification of daunorubicin and cytarabine during treatment of adult acute lymphoblastic leukemia: results of Cancer and Leukemia Group B Study 19802.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Survival Rate; Young Adult | 2013 |
Treatment of young patients with Philadelphia chromosome-positive acute lymphoblastic leukaemia using increased dose of imatinib and deintensified chemotherapy before allogeneic stem cell transplantation.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Combined Modality Therapy; Cytarabine; Daunorubicin; Dexamethasone; Disease-Free Survival; Etoposide; Female; Humans; Imatinib Mesylate; Male; Mercaptopurine; Methotrexate; Middle Aged; Piperazines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Pyrimidines; Stem Cell Transplantation; Transplantation, Homologous; Treatment Outcome; Vincristine; Young Adult | 2012 |
Effect of alternate-week versus continuous dexamethasone scheduling on the risk of osteonecrosis in paediatric patients with acute lymphoblastic leukaemia: results from the CCG-1961 randomised cohort trial.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cohort Studies; Cytarabine; Daunorubicin; Dexamethasone; Disease-Free Survival; Drug Administration Schedule; Female; Humans; Incidence; Infant; Male; Methotrexate; Osteonecrosis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Sex Distribution; Sex Factors; Survival Rate; Treatment Outcome; Vincristine; Young Adult | 2012 |
Cognitive outcomes following contemporary treatment without cranial irradiation for childhood acute lymphoblastic leukemia.
Topics: Adolescent; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Attention; Child; Child, Preschool; Cognition; Cranial Irradiation; Cytarabine; Dexamethasone; Drug Administration Schedule; Female; Humans; Hydrocortisone; Infant; Injections, Spinal; Intelligence; Intelligence Tests; Logistic Models; Male; Mercaptopurine; Methotrexate; Multivariate Analysis; Patient Selection; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Risk Factors; Sex Factors; Time Factors; Treatment Outcome; Vincristine | 2012 |
Phase I/II trial of clofarabine and cytarabine in children with relapsed/refractory acute lymphoblastic leukemia (AAML0523): a report from the Children's Oncology Group.
Topics: Adenine Nucleotides; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Child; Child, Preschool; Clofarabine; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Infant; Kaplan-Meier Estimate; Male; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Young Adult | 2013 |
Treatment reduction for children and young adults with low-risk acute lymphoblastic leukaemia defined by minimal residual disease (UKALL 2003): a randomised controlled trial.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Disease-Free Survival; Female; Humans; Infant; Ireland; Male; Methotrexate; Neoplasm, Residual; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Risk Factors; Treatment Outcome; United Kingdom; Vincristine | 2013 |
Phase I trial and correlative laboratory studies of bryostatin 1 (NSC 339555) and high-dose 1-B-D-arabinofuranosylcytosine in patients with refractory acute leukemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bryostatins; Cytarabine; Female; Humans; Infusions, Intravenous; Lactones; Leukemia, Myeloid; Macrolides; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinase C; Tumor Cells, Cultured | 2002 |
A single high dose of idarubicin combined with high-dose ARA-C for treatment of first relapse in childhood 'high-risk' acute lymphoblastic leukaemia: a study of the AIEOP group.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Disease-Free Survival; Female; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Infant; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Survival Rate | 2002 |
High-dose cytarabine in upfront therapy for adult patients with acute lymphoblastic leukaemia.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Drug Administration Schedule; Female; Hematopoietic Stem Cell Transplantation; Humans; Immunophenotyping; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Risk Factors; Survival Rate | 2002 |
A single, high dose of idarubicin combined with cytarabine as induction therapy for adult patients with recurrent or refractory acute lymphoblastic leukemia.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cognition; Conjunctivitis; Cytarabine; Dose-Response Relationship, Drug; Female; Fever; Heart; Hematemesis; Humans; Idarubicin; Male; Middle Aged; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Survival Analysis; Treatment Outcome | 2002 |
Prospective randomized trial to evaluate two delayed granulocyte colony stimulating factor administration schedules after high-dose cytarabine therapy in adult patients with acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Female; Granulocyte Colony-Stimulating Factor; Hematopoiesis; Humans; Male; Middle Aged; Neutropenia; Opportunistic Infections; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Treatment Outcome | 2002 |
[Results of the treatment of childhood acute lymphoblastic leukemia according to the Berlin-Moscow-91 protocol in 1991-2000].
Topics: Adolescent; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cytarabine; Data Interpretation, Statistical; Daunorubicin; Dexamethasone; Female; Follow-Up Studies; Humans; Infant; Male; Mercaptopurine; Methotrexate; Moscow; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Risk Factors; Russia; Survival Analysis; Time Factors; Vincristine | 2002 |
Lineage specific treatment of adult patients with acute lymphoblastic leukemia in first remission with anti-B4-blocked ricin or high-dose cytarabine: Cancer and Leukemia Group B Study 9311.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Female; Genes, abl; Humans; Immunoconjugates; Infusions, Intravenous; Male; Middle Aged; Polymerase Chain Reaction; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, Antigen, T-Cell; Ricin; Treatment Outcome | 2003 |
The dose related effect of steroids on blast reduction rate and event free survival in children with acute lymphoblastic leukemia.
Topics: Adolescent; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Disease-Free Survival; Dose-Response Relationship, Drug; Etoposide; Female; Humans; Male; Methotrexate; Methylprednisolone; Neoplastic Stem Cells; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Remission Induction; Retrospective Studies; Survival Analysis; Treatment Outcome; Vincristine | 2003 |
[The assessment of plasma levels of insulin-like growth factor (IGF-I) and binding protein (IGFBP-3) during the maintenance therapy and after remissionof acute lymphoblastic leukemia (ALL)].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Body Height; Body Mass Index; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Humans; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Puberty; Radiotherapy, Adjuvant; Remission Induction; Vincristine | 2003 |
[Improved results in children with acute lymphoblastic leukemia treated with the ALL-BFM 90 protocol in the Czech Republic].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Follow-Up Studies; Humans; Infant; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Recurrence; Vincristine | 2003 |
Apoptosis induction in peripheral leukemia cells by remission induction treatment in vivo: selective depletion and apoptosis in a CD34+ subpopulation of leukemia cells.
Topics: Adult; Antigens, CD; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Child; Cytarabine; Etoposide; fas Receptor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Leukocyte Count; Leukocytes, Mononuclear; Lymphocyte Depletion; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Treatment Outcome | 2003 |
A randomized trial of induction therapy (daunorubicin, vincristine, prednisone versus daunorubicin, vincristine, prednisone, cytarabine and 6-thioguanine) in adult acute lymphoblastic leukemia with long-term follow-up: an Eastern Cooperative Oncology Grou
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Life Tables; Male; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prednisone; Remission Induction; Survival Analysis; Thioguanine; Treatment Outcome; Vincristine | 2003 |
[Effect of modified FLAG regimen therapy on 33 patients with relapsed/refractory leukemia].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Treatment Outcome; Vidarabine | 2003 |
Rescue therapy combining intermediate-dose cytarabine with amsacrine and etoposide in relapsed adult acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Amsacrine; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Recurrence; Salvage Therapy; Survival Analysis; Treatment Outcome | 2004 |
Treatment of acute leukemia with idarubicin, etoposide and cytarabine (IDEA). A randomized study of etoposide schedule.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Etoposide; Humans; Idarubicin; Middle Aged; Mouth Mucosa; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome | 2004 |
Combination of liposomal daunorubicin (DaunoXome), fludarabine, and cytarabine (FLAD) in patients with poor-risk acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Risk Factors; Survival Rate; Vidarabine | 2004 |
Antileukemic and long-term effects of two regimens with or without TBI in allogeneic bone marrow transplantation for childhood acute lymphoblastic leukemia.
Topics: Adolescent; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cytarabine; Female; Graft vs Host Disease; Humans; Immunophenotyping; Karyotyping; Male; Melphalan; Organophosphates; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Time Factors; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome | 2004 |
Idarubicin and standard-dose cytosine arabinoside in adults with recurrent and refractory acute lymphocytic leukemia.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Humans; Idarubicin; Infusions, Intravenous; Injections, Intravenous; Male; Middle Aged; Neoplasm Recurrence, Local; Pilot Projects; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Survival Rate; Thrombocytopenia | 2004 |
Toxicity and efficacy of intensive chemotherapy for children with acute lymphoblastic leukemia (ALL) after first bone marrow or extramedullary relapse.
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bacteremia; Bone Marrow Neoplasms; Child; Child, Preschool; Cytarabine; Dexamethasone; Etoposide; Female; Flow Cytometry; Humans; Idarubicin; Ifosfamide; Infant; Infusions, Intravenous; Leucovorin; Male; Mesna; Methotrexate; Mouth Mucosa; Polyethylene Glycols; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Stomatitis; Thioguanine; Treatment Outcome; Vincristine | 2004 |
Clofarabine in adult acute leukemias: clinical success and pharmacokinetics.
Topics: Adenine Nucleotides; Adult; Antimetabolites, Antineoplastic; Arabinonucleosides; Clinical Trials as Topic; Clofarabine; Cohort Studies; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Models, Chemical; Myelodysplastic Syndromes; Neoplasm Metastasis; Neoplasms; Nucleosides; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome | 2004 |
Role of liposomal daunorubicin, fludarabine and cytarabine (FLAD) in the salvage therapy of adult acute lymphoblastic leukemia.
Topics: Adult; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Liposomes; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Salvage Therapy; Treatment Outcome; Vidarabine | 2004 |
Impact of TCR status and genotype on outcome in adult T-cell acute lymphoblastic leukemia: a LALA-94 study.
Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Genotype; Humans; Immunophenotyping; Incidence; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Receptors, Antigen, T-Cell; Recurrence; Survival Rate | 2005 |
Significant reduction of the hybrid BCR/ABL transcripts after induction and consolidation therapy is a powerful predictor of treatment response in adult Philadelphia-positive acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Fusion Proteins, bcr-abl; Humans; Male; Middle Aged; Neoplasm, Residual; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Predictive Value of Tests; Prognosis; Reverse Transcriptase Polymerase Chain Reaction; Vincristine | 2005 |
Phase II trial of amsacrine plus intermediate-dose Ara-C (IDAC) with or without etoposide as salvage therapy for refractory or relapsed acute leukemia.
Topics: Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Diarrhea; Drug Administration Schedule; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Nausea; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Salvage Therapy; Survival Rate; Treatment Outcome; Vomiting, Anticipatory | 2005 |
Burkitt lymphoma in adults: a prospective study of 72 patients treated with an adapted pediatric LMB protocol.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Cyclophosphamide; Cytarabine; Disease-Free Survival; Doxorubicin; Etoposide; Female; Humans; Hydrocortisone; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Staging; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Prospective Studies; Survival Rate; Vincristine | 2005 |
Phase I and pharmacokinetic study of flavopiridol followed by 1-beta-D-arabinofuranosylcytosine and mitoxantrone in relapsed and refractory adult acute leukemias.
Topics: Adult; Aged; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells; Cattle; Cell Proliferation; Cohort Studies; Cytarabine; Endothelium, Vascular; Female; Flavonoids; Humans; Leukemia, Myeloid, Acute; Male; Maximum Tolerated Dose; Middle Aged; Mitoxantrone; Neoplasm Recurrence, Local; Piperidines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Salvage Therapy; U937 Cells; Vascular Endothelial Growth Factor A | 2005 |
Role of treatment intensification in infants with acute lymphoblastic leukemia: results of two consecutive AIEOP studies.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cyclophosphamide; Cytarabine; Daunorubicin; Disease-Free Survival; Hematopoietic Stem Cell Transplantation; Humans; Infant, Newborn; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Vincristine | 2006 |
Intrathecal triple therapy decreases central nervous system relapse but fails to improve event-free survival when compared with intrathecal methotrexate: results of the Children's Cancer Group (CCG) 1952 study for standard-risk acute lymphoblastic leukemi
Topics: Age Factors; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Neoplasms; Central Nervous System; Central Nervous System Neoplasms; Child; Child, Preschool; Cytarabine; Disease-Free Survival; Female; Humans; Hydrocortisone; Injections, Spinal; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Retrospective Studies; Risk Factors; Sex Factors; T-Lymphocytes; Testicular Neoplasms; Time Factors | 2006 |
Fludarabine, cytarabine, and mitoxantrone (FLAM) for the treatment of relapsed and refractory adult acute lymphoblastic leukemia. A phase study by the Polish Adult Leukemia Group (PALG).
Topics: Adolescent; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Humans; Male; Middle Aged; Mitoxantrone; Poland; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Sepsis; Time Factors; Transplantation, Homologous; Vidarabine | 2006 |
Body mass index does not influence pharmacokinetics or outcome of treatment in children with acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Body Mass Index; Child; Child, Preschool; Cytarabine; Disease-Free Survival; Female; Humans; Infant; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Predictive Value of Tests; Remission Induction; Retrospective Studies; Teniposide | 2006 |
Imatinib combined with induction or consolidation chemotherapy in patients with de novo Philadelphia chromosome-positive acute lymphoblastic leukemia: results of the GRAAPH-2003 study.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Cytarabine; Female; Hematopoietic Stem Cell Transplantation; Humans; Imatinib Mesylate; Male; Middle Aged; Mitoxantrone; Neoplasm, Residual; Philadelphia Chromosome; Piperazines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyrimidines; Remission Induction; Survival Analysis; Transplantation, Homologous | 2007 |
Results of the PETHEMA ALL-96 trial in elderly patients with Philadelphia chromosome-negative acute lymphoblastic leukemia.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Comorbidity; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Disease-Free Survival; Female; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Humans; Kaplan-Meier Estimate; Male; Mercaptopurine; Methotrexate; Middle Aged; Neutropenia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Remission Induction; Severity of Illness Index; Survival Analysis; Teniposide; Treatment Outcome; Vincristine | 2007 |
Neurologic complications associated with intrathecal liposomal cytarabine given prophylactically in combination with high-dose methotrexate and cytarabine to patients with acute lymphocytic leukemia.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Encephalitis; Female; Humans; Injections, Spinal; Leukemic Infiltration; Liposomes; Male; Meninges; Meningitis; Methotrexate; Middle Aged; Papilledema; Polyradiculopathy; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Seizures; Vincristine | 2007 |
High-dose idarubicin in combination with Ara-C in patients with relapsed or refractory acute lymphoblastic leukemia: a pharmacokinetic and clinical study.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; Humans; Idarubicin; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Survival Analysis | 2007 |
[Multicenter randomized control trial on safety of domestic idarubicin for acute leukemia].
Topics: Adolescent; Adult; Aged; Agranulocytosis; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Cyclophosphamide; Cytarabine; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Mucositis; Nausea; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Treatment Outcome; Vincristine | 2006 |
[Auditory evoked potentials in patients after acute children's lymphoblastic leukemia treatment].
Topics: Acoustic Stimulation; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Evoked Potentials, Auditory, Brain Stem; Female; Hearing Disorders; Hearing Tests; Humans; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Reaction Time; Thioguanine; Vincristine | 2006 |
[Modified BFM-90 regimen greatly improves treatment outcomes of chinese childhood and adolescent lymphoblastic lymphoma].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asian People; Asparaginase; Child; Child, Preschool; China; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Male; Mercaptopurine; Methotrexate; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Treatment Outcome; Vincristine | 2007 |
Evaluation of renal function in Turkish children receiving BFM-95 therapy for acute lymphoblastic leukemia.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Kidney Diseases; Kidney Function Tests; Longitudinal Studies; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Turkey; Vincristine | 2007 |
Phase II study of chemotherapy and stem cell transplantation for adult acute lymphoblastic leukemia or lymphoblastic lymphoma: Japan Clinical Oncology Group Study 9004.
Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Cytarabine; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Male; Mercaptopurine; Methotrexate; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stem Cell Transplantation; Transplantation, Autologous | 2007 |
A treatment protocol for infants younger than 1 year with acute lymphoblastic leukaemia (Interfant-99): an observational study and a multicentre randomised trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Follow-Up Studies; Humans; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone | 2007 |
[The results of a multicenter trial of acute lymphoblastic leukemia treatment on ALL-MB 91/ALL-BFM 90m in children: analysis of efficacy and toxicity].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Treatment Outcome; Vincristine | 2007 |
Neuropsychological outcomes from a randomized trial of triple intrathecal chemotherapy compared with 18 Gy cranial radiation as CNS treatment in acute lymphoblastic leukemia: findings from Dana-Farber Cancer Institute ALL Consortium Protocol 95-01.
Topics: Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Diseases; Central Nervous System Neoplasms; Child; Child, Preschool; Cranial Irradiation; Cytarabine; Female; Glucocorticoids; Humans; Hydrocortisone; Infant; Injections, Spinal; Male; Methotrexate; Neuropsychological Tests; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2007 |
Outcome after relapse among children with standard-risk acute lymphoblastic leukemia: Children's Oncology Group study CCG-1952.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Female; Humans; Hydrocortisone; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Stem Cell Transplantation; Survival Analysis; Thioguanine; Treatment Outcome | 2007 |
Long-term results of the AIEOP-ALL-95 Trial for Childhood Acute Lymphoblastic Leukemia: insight on the prognostic value of DNA index in the framework of Berlin-Frankfurt-Muenster based chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Chi-Square Distribution; Child, Preschool; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Cytarabine; Daunorubicin; DNA, Neoplasm; Female; Humans; Infant; Italy; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Remission Induction; Survival Rate; Treatment Outcome; Vincristine | 2008 |
Risk-adjusted therapy of acute lymphoblastic leukemia can decrease treatment burden and improve survival: treatment results of 2169 unselected pediatric and adolescent patients enrolled in the trial ALL-BFM 95.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Child; Child, Preschool; Cranial Irradiation; Cytarabine; Female; Humans; Infant; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Risk Assessment; Secondary Prevention; Survival Analysis | 2008 |
Results of the first randomized multicentre trial on childhood acute lymphoblastic leukaemia in Russia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cytarabine; Daunorubicin; Feasibility Studies; Female; Humans; Infant; Infant, Newborn; Male; Methotrexate; Palliative Care; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Russia; Treatment Outcome; Vincristine | 2008 |
Comparison of the results of the treatment of adolescents and young adults with standard-risk acute lymphoblastic leukemia with the Programa Español de Tratamiento en Hematología pediatric-based protocol ALL-96.
Topics: Adolescent; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Hematologic Diseases; Humans; Hydrocortisone; Infant; Infections; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Treatment Outcome; Vincristine | 2008 |
Changes of cerebral biopterin and biogenic amine metabolism in leukemic children receiving 5 g/m2 intravenous methotrexate.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Biogenic Amines; Biopterins; Brain Chemistry; Child; Child, Preschool; Chromatography, High Pressure Liquid; Cytarabine; Dihydropteridine Reductase; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Infusions, Intravenous; Male; Mercaptopurine; Methotrexate; Nerve Tissue Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies | 1995 |
Concomitant granulocyte colony-stimulating factor and induction chemoradiotherapy in adult acute lymphoblastic leukemia: a randomized phase III trial.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Cytarabine; Disease-Free Survival; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Humans; Immunologic Factors; Infection Control; Male; Mercaptopurine; Methotrexate; Middle Aged; Neutropenia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Recombinant Proteins; Remission Induction; Survival Analysis; Treatment Outcome | 1995 |
Assessment of the value of treatment with granulocyte colony-stimulating factor in children with acute lymphoblastic leukemia: a randomized clinical trial.
Topics: Adolescent; Bacterial Infections; Child; Child, Preschool; Cytarabine; Female; Fever; Granulocyte Colony-Stimulating Factor; Humans; Infant; Male; Neutropenia; Outcome Assessment, Health Care; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1995 |
L-asparaginase may potentiate the leukemogenic effect of the epipodophyllotoxins.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Synergism; Etoposide; Humans; Infant; Karyotyping; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Neoplasms, Second Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone | 1995 |
Extended intrathecal methotrexate may replace cranial irradiation for prevention of CNS relapse in children with intermediate-risk acute lymphoblastic leukemia treated with Berlin-Frankfurt-Münster-based intensive chemotherapy. The Associazione Italiana d
Topics: Adolescent; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Brain Neoplasms; Child; Child, Preschool; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Infant; Injections, Spinal; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Recurrence; Regression Analysis; Remission Induction; Survival Analysis; Vincristine | 1995 |
Cognitive sequelae of treatment in childhood acute lymphoblastic leukemia: cranial radiation requires an accomplice.
Topics: Analysis of Variance; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child; Child, Preschool; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Female; Humans; Injections, Intravenous; Injections, Spinal; Intelligence; Intelligence Tests; Male; Memory Disorders; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radiotherapy; Sex Factors | 1995 |
Outcome of treatment in adult acute lymphoblastic leukaemia in an Asian population: comparison with previous multicentre German study.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asia; Asparaginase; Cytarabine; Daunorubicin; Dexamethasone; Doxorubicin; Ethnicity; Female; Follow-Up Studies; Germany; Humans; Malaysia; Male; Methotrexate; Methylprednisolone; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Probability; Racial Groups; Survival Rate; Time Factors; Treatment Outcome; Vincristine | 1995 |
Fractionated total-body irradiation preceding high-dose cytosine arabinoside as a preparative regimen for bone marrow transplantation in children with acute leukemia.
Topics: Adolescent; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Humans; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Survival Analysis; Whole-Body Irradiation | 1995 |
[Extramedullary relapse in childhood acute lymphoblastic leukemia: experience at the Kyushu Yamaguchi Children's Cancer Study Group].
Topics: Adolescent; Child; Child, Preschool; Cytarabine; Female; Humans; Infant; Male; Methotrexate; Ovarian Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radiotherapy Dosage; Testicular Neoplasms | 1995 |
[Treatment for elderly patients with acute non-lymphocytic leukemia].
Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Male; Mercaptopurine; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction; Retrospective Studies; Survival Rate | 1995 |
A five-drug remission induction regimen with intensive consolidation for adults with acute lymphoblastic leukemia: cancer and leukemia group B study 8811.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Drug Administration Schedule; Female; Humans; Immunophenotyping; Life Tables; Male; Mercaptopurine; Methotrexate; Middle Aged; Multivariate Analysis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prospective Studies; Remission Induction; Risk Factors; Survival Analysis; Thioguanine; Treatment Outcome; Vincristine | 1995 |
Comparison of treatment regimens for pediatric lymphoblastic non-Hodgkin's lymphoma: a Childrens Cancer Group study.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cause of Death; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Doxorubicin; Female; Humans; Infant; Lymphoma, Non-Hodgkin; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Recurrence; Thioguanine; Treatment Failure; Vincristine | 1995 |
Non-Hodgkin's lymphomas of childhood and adolescence: results of a treatment stratified for biologic subtypes and stage--a report of the Berlin-Frankfurt-Münster Group.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Child; Child, Preschool; Clinical Protocols; Cyclophosphamide; Cytarabine; Dexamethasone; Disease-Free Survival; Doxorubicin; Drug Administration Schedule; Etoposide; Follow-Up Studies; Humans; Ifosfamide; Infant; Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Time Factors | 1995 |
High-dose Ara-C for remission induction and consolidation of previously untreated adults with ALL or lymphoblastic lymphoma.
Topics: Adolescent; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Dose-Response Relationship, Drug; Etoposide; Female; Humans; Male; Methotrexate; Middle Aged; Pilot Projects; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Survival Rate; Time Factors; Vincristine | 1995 |
Prolonged intrathecal chemotherapy replacing cranial irradiation in high-risk acute lymphatic leukaemia: long-term follow up with cerebral computed tomography scans and endocrinological studies.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain; Child; Child, Preschool; Cranial Irradiation; Cytarabine; Disease-Free Survival; Female; Follow-Up Studies; Growth; Humans; Hydrocortisone; Injections, Spinal; Male; Methotrexate; Pituitary Hormones, Anterior; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Thyroid Hormones; Tomography, X-Ray Computed | 1995 |
Cerebrospinal fluid drug levels of leukemic children receiving intravenous 5 g/m2 methotrexate.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Child; Child, Preschool; Cytarabine; Female; Follow-Up Studies; Humans; Infant; Infusions, Intravenous; Leucovorin; Male; Meningeal Neoplasms; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Risk Factors | 1994 |
Comparative analysis of engraftment after cryopreservation of peripheral blood stem cell autografts by controlled- versus uncontrolled-rate methods.
Topics: Adolescent; Blood Transfusion, Autologous; Child; Child, Preschool; Combined Modality Therapy; Cryopreservation; Cyclophosphamide; Cytarabine; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Drug Therapy, Combination; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Infant; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Whole-Body Irradiation | 1994 |
High efficacy of the German multicenter ALL (GMALL) protocol for treatment of adult acute lymphoblastic leukemia (ALL)--a single-institution study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Austria; Cyclophosphamide; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Male; Mercaptopurine; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Remission Induction; Vincristine | 1994 |
Adult acute lymphoblastic leukemia: results of an aggressive regimen in India.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Humans; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Vincristine | 1994 |
[Clinical trial of protocol-AL851 for children with high-risk acute lymphoblastic leukemia. Kyushu Yamaguchi Children's Cancer Study Group (KYCCSG)].
Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Male; Methotrexate; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Risk; Survival Rate | 1994 |
Acute lymphoblastic leukaemia in infancy: experience in MRC UKALL trials. Report from the Medical Research Council Working Party on Childhood Leukaemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Drug Administration Schedule; Etoposide; Female; Humans; Infant; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Remission Induction; Survival Analysis; Transplantation, Autologous | 1994 |
Comparison of two schedules of intermediate-dose methotrexate and cytarabine consolidation therapy for childhood B-precursor cell acute lymphoblastic leukemia: a Pediatric Oncology Group study.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Diseases; Child; Child, Preschool; Cytarabine; Drug Administration Schedule; Female; Humans; Infant; Male; Methotrexate; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Risk Factors; United States | 1994 |
High-dose mercaptopurine followed by intermediate-dose cytarabine in relapsed acute leukemia.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Drug Administration Schedule; Feasibility Studies; Female; Humans; Infusions, Intravenous; Leukemia, Myeloid; Male; Mercaptopurine; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Treatment Outcome | 1994 |
Effects of bone marrow transplantation on myocardial function in children.
Topics: Adolescent; Adult; Blood Pressure; Bone Marrow Transplantation; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dose-Response Relationship, Drug; Echocardiography; Female; Heart; Humans; Infant; Leukemia, Myeloid, Acute; Male; Melphalan; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radionuclide Angiography; Time Factors; Transplantation, Autologous; Transplantation, Homologous; Whole-Body Irradiation | 1994 |
Chlorpromazine with and without lorazepam as antiemetic therapy in children receiving uniform chemotherapy.
Topics: Adolescent; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Chlorpromazine; Cytarabine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Infant; Lorazepam; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Teniposide; Vomiting | 1993 |
The role of radiation therapy in the treatment of acute lymphoblastic leukemia with lymphomatous presentation: a report from the Childrens Cancer Group.
Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Brain Neoplasms; Child; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Humans; Infant; Leukocyte Count; Lymphoma; Mediastinal Neoplasms; Meningeal Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Recurrence; Survival Rate; Thioguanine; Vincristine | 1993 |
The role of systemic high-dose cytarabine in the treatment of central nervous system leukemia. Clinical results in 46 patients.
Topics: Adolescent; Adult; Aged; Cytarabine; Drug Administration Schedule; Female; Humans; Lymphoma, Non-Hodgkin; Male; Meningeal Neoplasms; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome | 1993 |
Follow-up of the first two successive German multicentre trials for adult ALL (01/81 and 02/84). German Adult ALL Study Group.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cranial Irradiation; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Drug Administration Schedule; Follow-Up Studies; Humans; Mediastinum; Mercaptopurine; Methotrexate; Middle Aged; Pilot Projects; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prospective Studies; Remission Induction; Survival Analysis; Teniposide; Vincristine | 1993 |
Treatment results of three consecutive Brazilian cooperative childhood ALL protocols: GBTLI-80, GBTLI-82 and -85. ALL Brazilian Group.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Cranial Irradiation; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Drug Administration Schedule; Humans; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Remission Induction; Teniposide; Vincristine | 1993 |
Fludarabine and cytosine arabinoside in the treatment of refractory or relapsed acute lymphocytic leukemia.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Drug Evaluation; Female; Humans; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Survival Rate; Treatment Outcome; Vidarabine | 1993 |
Chemotherapy induced nausea and emesis in pediatric cancer patients: external validity of child and parent emesis ratings.
Topics: Adolescent; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Anxiety; Attitude; Child; Child, Preschool; Cytarabine; Double-Blind Method; Female; Humans; Infant; Male; Nausea; Parents; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Severity of Illness Index; Sick Role; Teniposide; Vomiting | 1993 |
Phase I clinical and pharmacokinetic evaluation of high-dose mitoxantrone in combination with cytarabine in patients with acute leukemia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Chemical and Drug Induced Liver Injury; Cytarabine; Drug Administration Schedule; Female; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Accelerated Phase; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1993 |
Treatment of late bone marrow relapse in children with acute lymphoblastic leukemia: a Pediatric Oncology Group study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Child; Child, Preschool; Cytarabine; Female; Humans; Leukocyte Count; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Retrospective Studies; Teniposide; Time Factors; Treatment Failure | 1993 |
Use of cytosine arabinoside and total body irradiation as conditioning for allogeneic marrow transplantation in patients with acute lymphoblastic leukemia: a multicenter survey.
Topics: Adolescent; Adult; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Female; Humans; Infant; Male; Middle Aged; Multivariate Analysis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Survival Rate; Whole-Body Irradiation | 1993 |
Phase-II study of treatment of refractory acute leukemia with intermediate-dose cytosine arabinoside and amsacrine.
Topics: Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Resistance; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction | 1993 |
Randomized comparison of 36-hour intermediate-dose versus 4-hour high-dose methotrexate infusions for remission induction in relapsed childhood acute lymphoblastic leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Vincristine | 1993 |
[Results of the CCLSG high risk ALL 874 protocol in childhood acute lymphoblastic leukemia. Children's Cancer and Leukemia Study Group].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Doxorubicin; Female; Humans; Leukocyte Count; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Remission Induction; Risk; Vincristine | 1993 |
Severe toxicity limits intensification of induction therapy for acute lymphoblastic leukemia.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Idarubicin; Male; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Survival Analysis; Vincristine | 1993 |
A randomized phase-III study of the efficacy of granulocyte colony-stimulating factor in children with high-risk acute lymphoblastic leukemia. Berlin-Frankfurt-Münster Study Group.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cytarabine; Daunorubicin; Dexamethasone; Disease-Free Survival; Etoposide; Female; Fever; Filgrastim; Gastrointestinal Diseases; Germany; Granulocyte Colony-Stimulating Factor; Hematologic Diseases; Humans; Ifosfamide; Infant; Infection Control; Life Tables; Male; Mercaptopurine; Methotrexate; Neutropenia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prospective Studies; Recombinant Proteins; Risk; Survival Analysis; Thioguanine; Vincristine; Vindesine | 1996 |
The GIMEMA ALL 0183 trial: analysis of 10-year follow-up. GIMEMA Cooperative Group, Italy.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Follow-Up Studies; Humans; Idarubicin; Male; Methotrexate; Middle Aged; Multivariate Analysis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Survival Analysis; Survival Rate | 1996 |
FLAG (fludarabine, cytarabine, G-CSF) as a second line therapy for acute lymphoblastic leukemia with myeloid antigen expression: in vitro and in vivo effects.
Topics: Adult; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Conjunctivitis; Cytarabine; Disease-Free Survival; Female; Glucocorticoids; Granulocyte Colony-Stimulating Factor; Humans; Male; Middle Aged; Ophthalmic Solutions; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Vidarabine | 1996 |
Improved survival for children with B-cell acute lymphoblastic leukemia and stage IV small noncleaved-cell lymphoma: a pediatric oncology group study.
Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Doxorubicin; Female; Humans; Infant; Injections, Spinal; Lymphoma, Non-Hodgkin; Male; Methotrexate; Neoplasm Staging; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Survival Analysis; Treatment Outcome; Vincristine | 1996 |
Relationship between minimal residual disease and outcome in adult acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow; Bone Marrow Transplantation; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Resistance, Neoplasm; Etoposide; Gene Rearrangement, B-Lymphocyte, Heavy Chain; Humans; Mercaptopurine; Methotrexate; Middle Aged; Neoplasm, Residual; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Survival Analysis; Treatment Outcome; Vincristine | 1996 |
Incidence and clinical outcome of children with BCR/ABL-positive acute lymphoblastic leukemia (ALL). A prospective RT-PCR study based on 673 patients enrolled in the German pediatric multicenter therapy trials ALL-BFM-90 and CoALL-05-92.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Base Sequence; Child; Child, Preschool; Chromosomes, Human, Pair 22; Chromosomes, Human, Pair 9; Cyclophosphamide; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Fusion Proteins, bcr-abl; Germany; Humans; Incidence; Infant; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Mercaptopurine; Methotrexate; Molecular Sequence Data; Polymerase Chain Reaction; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Prospective Studies; Transcription, Genetic; Translocation, Genetic; Vincristine | 1996 |
[Nephrotoxicity evaluation of cytostatic agents in children with acute lymphoblastic leukemia].
Topics: Acetylglucosaminidase; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Biomarkers; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Humans; Isoenzymes; Kidney Tubules; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Vincristine | 1995 |
Heterogeneous effects of G-CSF and GM-CSF on cell growth and ara-C cytotoxicity in childhood leukemias which express myeloid markers.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Cell Division; Child; Child, Preschool; Cytarabine; Drug Synergism; Female; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunophenotyping; Infant; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemia, Promyelocytic, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Thymidine; Tritium | 1996 |
Acute lymphoblastic leukemia in children: nonrandomized comparison of conventional vs. intensive chemotherapy at the National Cancer Institute of Colombia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Drug Administration Schedule; Feasibility Studies; Female; Humans; Infant; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Risk Factors; Treatment Outcome; Vincristine | 1997 |
Etoposide and mitoxantrone as a second cycle of consolidation therapy following high dose cytosine arabinoside and daunorubicin in patients with acute non-lymphocytic leukemia in remission: a pilot study.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Etoposide; Female; Follow-Up Studies; Humans; Male; Middle Aged; Mitoxantrone; Pilot Projects; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Remission Induction; Salvage Therapy | 1996 |
Intensive postremission chemotherapy without maintenance therapy in adults with acute lymphoblastic leukemia. Dutch Hemato-Oncology Research Group.
Topics: Adolescent; Adult; Amsacrine; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Drug Administration Schedule; Etoposide; Female; Humans; Male; Middle Aged; Mitoxantrone; Netherlands; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Treatment Outcome | 1997 |
Treatment of adult patients with relapsed or refractory acute lymphoblastic leukemia (ALL).
Topics: Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction | 1997 |
Eighty-one percent event-free survival in advanced Burkitt's lymphoma/leukemia: no differences in outcome between pediatric and adult patients treated with the same intensive pediatric protocol.
Topics: Adolescent; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Treatment Outcome; Vincristine | 1997 |
B-lineage acute lymphoblastic leukemia of childhood. An institutional experience.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Burkitt Lymphoma; Child; Child, Preschool; Cytarabine; Disease-Free Survival; Female; Humans; Immunophenotyping; Infant; Life Tables; Male; Mercaptopurine; Methotrexate; Neprilysin; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Risk Factors; Survival Analysis; Teniposide; Treatment Outcome; Vincristine | 1997 |
Treatment of adults with acute lymphoblastic leukaemia in first bone marrow relapse: results of the ALL R-87 protocol.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Female; Humans; Idarubicin; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prospective Studies; Recurrence; Survival Analysis; Survival Rate; Treatment Outcome | 1997 |
Treatment of relapsed adult acute lymphoblastic leukemia with fludarabine and cytosine arabinoside followed by granulocyte colony-stimulating factor (FLAG-GCSF).
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Male; Middle Aged; Neutropenia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Vidarabine | 1997 |
Phase I/II study of idarubicin given with continuous infusion fludarabine followed by continuous infusion cytarabine in children with acute leukemia: a report from the Children's Cancer Group.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Female; Humans; Idarubicin; Infant; Infusions, Intravenous; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Vidarabine | 1997 |
Thiopurine drugs in the treatment of childhood leukaemia: the influence of inherited thiopurine methyltransferase activity on drug metabolism and cytotoxicity.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Cyclophosphamide; Cytarabine; Dexamethasone; Erythrocytes; Etoposide; Female; Humans; Male; Mercaptopurine; Methotrexate; Methyltransferases; Phenotype; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Thioguanine; Vincristine | 1997 |
Allogeneic bone marrow transplantation for high-risk acute lymphoblastic leukemia in first remission: long-term results for 42 patients conditioned with an intensified regimen (TBI, high-dose Ara-C and melphalan).
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Burkitt Lymphoma; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Female; Follow-Up Studies; Humans; Leukemia-Lymphoma, Adult T-Cell; Male; Melphalan; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Whole-Body Irradiation | 1997 |
ALL R-87 protocol in the treatment of children with acute lymphoblastic leukaemia in early bone marrow relapse.
Topics: Adolescent; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Disease-Free Survival; Female; Humans; Idarubicin; Infant; Leukocyte Count; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prospective Studies; Recurrence; Risk Factors; Survival Analysis; Survival Rate; Treatment Outcome | 1997 |
Intensified therapy for infants with acute lymphoblastic leukemia: results from the Dana-Farber Cancer Institute Consortium.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Core Binding Factor Alpha 2 Subunit; Cytarabine; Disease-Free Survival; DNA-Binding Proteins; DNA, Neoplasm; Female; Histone-Lysine N-Methyltransferase; Humans; Infant; Infant, Newborn; Male; Mercaptopurine; Methotrexate; Myeloid-Lymphoid Leukemia Protein; Neoplasm Proteins; Oncogene Proteins, Fusion; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Proto-Oncogenes; Remission Induction; Survival Rate; Transcription Factors; Treatment Outcome; Vincristine | 1997 |
Conventional compared with individualized chemotherapy for childhood acute lymphoblastic leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Female; Humans; Infant; Leukemia, B-Cell; Male; Metabolic Clearance Rate; Methotrexate; Patient Care Planning; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proportional Hazards Models; Prospective Studies; Remission Induction; Survival Analysis; Teniposide | 1998 |
High-dose cytosine arabinoside and L-asparaginase in refractory acute lymphoblastic leukemia: the Children's Cancer Group experience.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cytarabine; Female; Humans; Infections; Infusions, Intravenous; Injections, Intramuscular; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Recurrence; Treatment Outcome | 1998 |
Pharmacokinetic and pharmacodynamic studies of fludarabine and cytosine arabinoside administered as loading boluses followed by continuous infusions after a phase I/II study in pediatric patients with relapsed leukemias. The Children's Cancer Group.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Child; Child, Preschool; Cytarabine; Humans; Infant; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Vidarabine | 1998 |
Estimated 6-year event-free survival of 55% in 60 consecutive adult acute lymphoblastic leukemia patients treated with an intensive phase II protocol based on high induction dose of daunorubicin.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Combined Modality Therapy; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Administration Schedule; Etoposide; Female; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Treatment Outcome; Vincristine | 1998 |
High-dose cytarabine-containing chemotherapy with or without granulocyte colony-stimulating factor for children with acute leukemia.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Female; Fever; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Infant; Infections; Leukemia, Myeloid; Male; Neutropenia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome | 1998 |
[Preliminary treatment results of relapsed or refractory acute leukemia using two and three drug regimens].
Topics: Adult; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Humans; Idarubicin; Male; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction | 1998 |
A phase I trial of a single high dose of idarubicin combined with high-dose cytarabine as induction therapy in relapsed or refractory adult patients with acute lymphoblastic leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Idarubicin; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1998 |
Improved survival with early intensification: combined results from the Medical Research Council childhood ALL randomised trials, UKALL X and UKALL XI. Medical Research Council Working Party on Childhood Leukaemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Daunorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Infant; Infant, Newborn; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Thioguanine; Vincristine | 1998 |
Total body irradiation-high-dose cytosine arabinoside and melphalan followed by allogeneic bone marrow transplantation from HLA-identical siblings in the treatment of children with acute lymphoblastic leukaemia after relapse while receiving chemotherapy:
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Central Nervous System Neoplasms; Child; Child, Preschool; Cytarabine; Disease-Free Survival; Female; Graft vs Host Disease; Humans; Male; Melphalan; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Recurrence; Testicular Neoplasms; Transplantation, Homologous; Whole-Body Irradiation | 1998 |
Changes in red blood cell methotrexate pharmacology and their impact on outcome when cytarabine is infused with methotrexate in the treatment of acute lymphocytic leukemia in children: a pediatric oncology group study.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Erythrocytes; Humans; Infant; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Prospective Studies | 1996 |
Intensive BFM chemotherapy for childhood ALL: interim analysis of the AIEOP-ALL 91 study. Associazione Italiana Ematologia Oncologia Pediatrica.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Child; Child, Preschool; Chromosome Aberrations; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Disease-Free Survival; Doxorubicin; Female; Humans; Infant; Italy; Leucovorin; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Remission Induction; Risk; Thioguanine; Treatment Outcome; Vincristine | 1998 |
[Studies of childhood non-Hodgkin's lymphoma--treatment results with the CCLSG NHL 960 protocol. Children's Cancer and Leukemia Study Group (CCLSG)].
Topics: Adolescent; Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Burkitt Lymphoma; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Doxorubicin; Etoposide; Female; Humans; Hydrocortisone; Infant; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction; Vincristine | 1998 |
[A phase II study with high-dose cytarabine (NS-075) in adult patients with relapsed and refractory acute leukemia].
Topics: Adolescent; Adult; Aged; Anorexia; Antimetabolites, Antineoplastic; Cytarabine; Diarrhea; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged; Nausea; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Vomiting | 1998 |
[Pilot late phase II study of KRN8602 (MX2), a novel anthracycline derivative, for acute leukemia--a dose finding study in combination].
Topics: Adult; Aged; Anorexia; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carubicin; Cytarabine; Female; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged; Nausea; Pilot Projects; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction; Vincristine; Vomiting, Anticipatory | 1999 |
Management of advanced acute lymphoblastic leukemia in children and adults: results of the ALL R-87 protocol. AIEOP and GIMEMA Cooperative Groups.
Topics: Adolescent; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Disease-Free Survival; Female; Humans; Idarubicin; Infant; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Recurrence; Remission Induction; Survival Rate; Treatment Outcome | 1998 |
A phase II study employing combination regimens containing KRN8602 in drug-resistant acute myeloid leukemia and acute lymphoblastic leukemia. KRN8602 Leukemia Study Group.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carubicin; Cytarabine; Drug Resistance, Neoplasm; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Treatment Failure; Vincristine | 1999 |
FLAG (fludarabine, high-dose cytarabine, and G-CSF) for refractory and high-risk relapsed acute leukemia in children.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Infant; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Treatment Outcome; Vidarabine | 1999 |
Improved outcome for acute lymphoblastic leukemia in children of a developing country: results of the Chilean National Trial PINDA 87.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Chile; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Cytarabine; Developing Countries; Female; Humans; Immunophenotyping; Infant; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prospective Studies; Survival Analysis; Vincristine | 1999 |
Persistence of peripheral blood and bone marrow blasts during remission induction in adult acute lymphoblastic leukemia confers a poor prognosis depending on treatment intensity.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Humans; Methotrexate; Middle Aged; Multivariate Analysis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Remission Induction; Time Factors; Vincristine | 1999 |
A randomised dose-comparison trial of granisetron in preventing emesis in children with leukaemia receiving emetogenic chemotherapy.
Topics: Adolescent; Antiemetics; Antineoplastic Agents; Child; Child, Preschool; Cross-Over Studies; Cytarabine; Dose-Response Relationship, Drug; Female; Granisetron; Humans; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1999 |
[Prevention of neuroleukemia by intrathecal administration of cytosar and methotrexate in acute lymphoblastic leukemia in adults].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cytarabine; Drug Therapy, Combination; Female; Humans; Immunophenotyping; Injections, Spinal; Male; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Risk Factors; Treatment Outcome | 1999 |
Effective preventive central nervous system therapy with extended triple intrathecal therapy and the modified ALL-BFM 86 chemotherapy program in an enlarged non-high risk group of children and adolescents with non-B-cell acute lymphoblastic leukemia: the
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Chemotherapy, Adjuvant; Child; Child, Preschool; Cytarabine; Female; Humans; Hydrocortisone; Infant; Injections, Spinal; Israel; Life Tables; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radiotherapy, Adjuvant; Risk; Treatment Outcome | 2000 |
Effects of G-CSF and high-dose methylprednisolone on peripheral stem cells, serum IL-3 levels and hematological parameters in acute lymphoblastic leukemia patients with neutropenia: a pilot study.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Etoposide; Glucocorticoids; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cells; Humans; Interleukin-3; Methotrexate; Methylprednisolone; Neutropenia; Pilot Projects; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Vincristine | 2000 |
Alternating drug pairs with or without periodic reinduction in children with acute lymphoblastic leukemia in second bone marrow remission: a Pediatric Oncology Group Study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Recurrence; Remission Induction; Teniposide; Vincristine | 2000 |
Benefit of intensified treatment for all children with acute lymphoblastic leukaemia: results from MRC UKALL XI and MRC ALL97 randomised trials. UK Medical Research Council's Working Party on Childhood Leukaemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Disease-Free Survival; Drug Administration Schedule; Etoposide; Female; Follow-Up Studies; Humans; Infant; Infections; Male; Methotrexate; Neoplasms, Second Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Proportional Hazards Models; Remission Induction; Risk; Survival Analysis; Thioguanine; Treatment Outcome; Vincristine | 2000 |
Use of recombinant human granulocyte colony-stimulating factor to increase chemotherapy dose-intensity: a randomized trial in very high-risk childhood acute lymphoblastic leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Dexamethasone; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Infant; Infant, Newborn; Male; Methotrexate; Neutropenia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Recombinant Proteins; Thrombocytopenia; Treatment Outcome; Vincristine | 2000 |
A phase II study of high dose ARA-C and mitoxantrone for treatment of relapsed or refractory adult acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Male; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Treatment Outcome | 2000 |
The UK experience in treating relapsed childhood acute lymphoblastic leukaemia: a report on the medical research council UKALLR1 study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dexamethasone; Disease-Free Survival; Epirubicin; Humans; Hydrocortisone; Infant; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Randomized Controlled Trials as Topic; Recurrence; Statistics, Nonparametric; Thioguanine; Transplantation, Homologous; Treatment Outcome; United Kingdom; Vincristine | 2000 |
Novel multiagent chemotherapy for bone marrow relapse of pediatric acute lymphoblastic leukemia.
Topics: Adolescent; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow; Bone Marrow Transplantation; Central Nervous System Neoplasms; Child; Child, Preschool; Cytarabine; Dexamethasone; Disease-Free Survival; Etoposide; Female; Follow-Up Studies; Humans; Idarubicin; Infant; Injections, Spinal; Male; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Vincristine | 2000 |
[Treatment of adult acute lymphoblastic leukemia by KHALL-93--long-term outcome].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Drug Administration Schedule; Female; Humans; Male; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Treatment Outcome | 2000 |
Value of high-dose cytarabine during interval therapy of a Berlin-Frankfurt-Munster-based protocol in increased-risk children with acute lymphoblastic leukemia and lymphoblastic lymphoma: results of the European Organization for Research and Treatment of
Topics: Actuarial Analysis; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Central Nervous System; Child; Child, Preschool; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Synergism; Europe; Female; Humans; Infant; Infant, Newborn; Infusions, Intravenous; Injections, Spinal; Leukemic Infiltration; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Regression Analysis; Risk; Vincristine | 2001 |
Determinants of outcome after intensified therapy of childhood lymphoblastic leukaemia: results from Medical Research Council United Kingdom acute lymphoblastic leukaemia XI protocol.
Topics: Adolescent; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Chromosome Aberrations; Chromosome Disorders; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Etoposide; Female; Humans; Infant; Leukocyte Count; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Remission Induction; Risk Factors; Sex Factors; Thioguanine; United Kingdom; Vincristine | 2001 |
The Société Française d'Oncologie Pédiatrique LMB89 protocol: highly effective multiagent chemotherapy tailored to the tumor burden and initial response in 561 unselected children with B-cell lymphomas and L3 leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Female; Humans; Hydrocortisone; Infant; Leucovorin; Lymphoma, B-Cell; Male; Methotrexate; Neoplasm Staging; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Recurrence; Remission Induction; Survival Rate; Vincristine | 2001 |
Daunorubicin continuous infusion induces more toxicity than bolus infusion in acute lymphoblastic leukemia induction regimen: a randomized study.
Topics: Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Carmustine; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Etoposide; Female; Gram-Negative Bacterial Infections; Humans; Immunocompromised Host; Infusions, Intravenous; Injections, Intravenous; Life Tables; Male; Methotrexate; Middle Aged; Neutropenia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Survival Analysis; Thrombocytopenia; Treatment Outcome; Vincristine | 2001 |
Risk-oriented postremission strategies in adult acute lymphoblastic leukemia: prospective confirmation of anthracycline activity in standard-risk class and role of hematopoietic stem cell transplants in high-risk groups.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Disease-Free Survival; Female; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Male; Melphalan; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Risk Factors; Transplantation, Homologous; Whole-Body Irradiation | 2001 |
Outcome of acute lymphoblastic leukemia in children with AL90 regimen: impact of response to treatment and sex difference on prognostic factors.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Disease-Free Survival; Drug Administration Schedule; Etoposide; Female; Humans; Immunophenotyping; Infant; Male; Mercaptopurine; Methotrexate; Multivariate Analysis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Radiotherapy, Adjuvant; Remission Induction; Risk; Risk Factors; Severity of Illness Index; Sex Factors; Survival Analysis; Treatment Outcome; Vincristine | 2001 |
Efficacy of fludarabine, intermittent sequential high-dose cytosine arabinoside, and mitoxantrone (FIS-HAM) salvage therapy in highly resistant acute leukemias.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Drug Administration Schedule; Drug Resistance; Humans; Leukemia; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Salvage Therapy; Therapeutic Equivalency; Treatment Outcome; Vidarabine | 2001 |
Brief-duration high-intensity chemotherapy for patients with small noncleaved-cell lymphoma or FAB L3 acute lymphocytic leukemia: results of cancer and leukemia group B study 9251.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System; Cyclophosphamide; Cytarabine; Drug Administration Schedule; Etoposide; Female; Humans; Ifosfamide; Infections; Injections, Spinal; Lymphoma, Non-Hodgkin; Male; Methotrexate; Neutropenia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Survival Analysis; Thrombocytopenia; Vincristine | 2001 |
Favorable outcome for children and adolescents with T-cell lymphoblastic lymphoma with an intensive ALL-type therapy without local radiotherapy.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Austria; Child; Child, Preschool; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Disease-Free Survival; Doxorubicin; Drug Administration Schedule; Female; Germany; Humans; Immunophenotyping; Infant; Life Tables; Lymphoma, T-Cell; Male; Mercaptopurine; Methotrexate; Neoplasm Staging; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Radiotherapy, Adjuvant; Remission Induction; Thioguanine; Treatment Outcome; Vincristine | 2001 |
Improved outcome in high-risk childhood acute lymphoblastic leukemia defined by prednisone-poor response treated with double Berlin-Frankfurt-Muenster protocol II.
Topics: Adolescent; Adrenal Cortex Hormones; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Drug Resistance; Female; Humans; Infant; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Risk Assessment; Survival Analysis; Thioguanine; Translocation, Genetic; Treatment Outcome; Vincristine | 2002 |
Treatment of acute lymphoblastic leukaemia (ALL).
Topics: Adolescent; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cyclophosphamide; Cytarabine; Doxorubicin; Female; Humans; Infusions, Intravenous; Injections, Spinal; Male; Mercaptopurine; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Survival Analysis; Vincristine | 1992 |
[Effectiveness of empirical antibiotic therapy in the control of infections in patients with acute leukemia during severe neutropenia].
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Bacterial Infections; Cytarabine; Daunorubicin; Female; Humans; Immune Tolerance; Leukemia, Myeloid, Acute; Male; Middle Aged; Neutropenia; Opportunistic Infections; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1992 |
[Experience with using aclarubicin in the treatment of acute leukemia and blast crisis of chronic myeloid leukemia].
Topics: Aclarubicin; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Cytarabine; Humans; Leukemia; Leukemia, Monocytic, Acute; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction | 1992 |
F-MACHOP in advanced aggressive lymphoma.
Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Doxorubicin; Fluorouracil; Humans; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Methotrexate; Neoplasm Staging; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Vincristine | 1992 |
Long-term neuropsychologic sequelae of childhood leukemia: comparison of two CNS prophylactic regimens.
Topics: Adolescent; Age Factors; Brain; Brain Neoplasms; Child; Cognition Disorders; Combined Modality Therapy; Cytarabine; Female; Humans; Intelligence; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis | 1992 |
Busulphan, cyclophosphamide, and melphalan as conditioning therapy in allogeneic bone marrow transplants for acute lymphoblastic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; Cyclophosphamide; Cytarabine; Graft vs Host Disease; Humans; Melphalan; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Whole-Body Irradiation | 1992 |
An update of the results of intensive therapy in children with acute lymphoblastic leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cause of Death; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Administration Schedule; Humans; Infant; Infant, Newborn; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Remission Induction; Survival Analysis | 1992 |
GIMEMA ALL 0288: a multicentric study on adult acute lymphoblastic leukemia. Preliminary results.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Clinical Protocols; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Vincristine | 1992 |
Adult acute lymphocytic leukemia: the Eastern Cooperative Oncology Group experience.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Administration Schedule; Humans; Methotrexate; Middle Aged; Pilot Projects; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Thioguanine; Vincristine | 1992 |
Treatment of adult acute lymphoblastic leukaemia (ALL) over a 16 year period.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cytarabine; Doxorubicin; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Recurrence; Remission Induction; Survival Analysis; Vincristine | 1992 |
Therapy of adult ALL: overview of 2 successive EORTC studies: (ALL-2 & ALL-3). The EORTC Leukemia Cooperative Study Group.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Humans; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Recurrence; Remission Induction; Survival Analysis; Transplantation, Autologous; Transplantation, Homologous | 1992 |
Early intensification followed by allo-BMT or auto-BMT or a second intensification in adult ALL: a randomized multicenter study.
Topics: Adolescent; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Feasibility Studies; Humans; Italy; Methotrexate; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Transplantation, Autologous; Transplantation, Homologous; Vincristine | 1992 |
Ceftazidime as initial therapy in febrile patients with acute leukemia during induction chemotherapy. Leukemia Group of Middle Sweden.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bacterial Infections; Ceftazidime; Cytarabine; Daunorubicin; Female; Fever; Fever of Unknown Origin; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Thioguanine | 1992 |
[Preliminary results of the treatment of acute leukemia with mitoxantrone].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Female; Humans; Injections, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction | 1991 |
Low-dose versus high-dose methotrexate during remission induction in childhood acute lymphoblastic leukemia (Protocol 81-01 update).
Topics: Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Cytarabine; Dose-Response Relationship, Drug; Doxorubicin; Follow-Up Studies; Humans; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Time Factors; Treatment Outcome; Vincristine | 1991 |
Idarubicin plus ARA-C followed by allogeneic or autologous bone marrow transplantation in advanced acute lymphoblastic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Humans; Idarubicin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Remission Induction; Transplantation, Autologous; Transplantation, Homologous | 1991 |
The effects of postinduction intensification treatment with cytarabine and daunorubicin in adult acute lymphocytic leukemia: a prospective randomized clinical trial by Cancer and Leukemia Group B.
Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pregnancy; Remission Induction; Survival Analysis | 1991 |
High survival rate in advanced-stage B-cell lymphomas and leukemias without CNS involvement with a short intensive polychemotherapy: results from the French Pediatric Oncology Society of a randomized trial of 216 children.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Female; Follow-Up Studies; Humans; Infant; Lymphoma, B-Cell; Male; Methotrexate; Neoplasm Staging; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Recurrence; Remission Induction; Survival Rate; Vincristine | 1991 |
HiC-COM: a 2-month intensive chemotherapy regimen for children with stage III and IV Burkitt's lymphoma and B-cell acute lymphoblastic leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Drug Administration Schedule; Feasibility Studies; Female; Follow-Up Studies; Humans; Male; Methotrexate; Neoplasm Staging; Pilot Projects; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Survival Rate; Vincristine | 1991 |
A pilot study of intermediate-dose methotrexate and cytosine arabinoside, "spread-out" or "up-front," in continuation therapy for childhood non-T, non-B acute lymphoblastic leukemia. A Pediatric Oncology Group study.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Cytarabine; Drug Administration Schedule; Female; Fever; Humans; Infant; Infections; Length of Stay; Leukocyte Count; Male; Methotrexate; Neutropenia; Pilot Projects; Platelet Count; Pneumonia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Survival Rate | 1991 |
The TAM regimen prior to allogeneic and autologous bone marrow transplantation for high-risk acute lymphoblastic leukemias: a cooperative study of 62 patients.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Humans; Melphalan; Pilot Projects; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Survival Analysis; Transplantation, Autologous; Transplantation, Homologous; Whole-Body Irradiation | 1991 |
Improved treatment results in boys with overt testicular relapse during or shortly after initial therapy for acute lymphoblastic leukemia. A Pediatric Oncology group study.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Humans; Infant; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Recurrence; Remission Induction; Risk Factors; Survival Rate; Teniposide; Testicular Neoplasms; Vincristine | 1991 |
Idarubicin and high-dose cytarabine in the treatment of refractory and relapsed acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Humans; Idarubicin; Infant; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence | 1990 |
Prevention of cyclophosphamide/cytarabine-induced emesis with ondansetron in children with leukemia.
Topics: Administration, Oral; Adolescent; Adult; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Drug Evaluation; Female; Humans; Imidazoles; Injections, Intravenous; Liver Function Tests; Male; Ondansetron; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Serotonin Antagonists; Vomiting | 1990 |
Intensive chemotherapy for acute lymphoblastic leukaemia in adults.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Combined Modality Therapy; Cytarabine; Doxorubicin; Humans; Italy; Life Tables; Multicenter Studies as Topic; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction; Survival Rate; United Kingdom; Vincristine | 1990 |
Treatment of relapsed acute lymphocytic leukemia in adults.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Brain Neoplasms; Combined Modality Therapy; Cytarabine; Daunorubicin; Dexamethasone; Etoposide; Female; Germany, West; Humans; Ifosfamide; Leucovorin; Life Tables; Male; Methotrexate; Middle Aged; Multicenter Studies as Topic; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Spinal Cord Neoplasms; Teniposide; Testicular Neoplasms; Vindesine | 1990 |
Improved prognosis for childhood acute lymphocytic leukemia with very high white blood cell count (greater than 100/nl) with rotation of non-cross-resistant drug combinations.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Germany, West; Humans; Infant; Infant, Newborn; Leukocyte Count; Mercaptopurine; Methotrexate; Multicenter Studies as Topic; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Randomized Controlled Trials as Topic; Risk; Survival Rate; Teniposide; Thioguanine; Vincristine | 1990 |
Results of the vincristine, doxorubicin, and dexamethasone regimen in adults with standard- and high-risk acute lymphocytic leukemia.
Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmustine; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Etoposide; Female; Humans; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Risk Factors; Vincristine | 1990 |
Bone marrow transplantation for acute lymphocytic leukemia utilizing total body irradiation followed by high doses of cytosine arabinoside: lack of superiority over cyclophosphamide-containing conditioning regimens.
Topics: Adolescent; Adult; Bone Marrow Transplantation; Child; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Female; Graft Survival; Graft vs Host Disease; Humans; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Whole-Body Irradiation | 1990 |
Teniposide (VM-26) and continuous infusion cytosine arabinoside for initial induction failure in childhood acute lymphoblastic leukemia. A Pediatric Oncology Group pilot study.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Female; Humans; Hydrocortisone; Infant; Infusions, Intravenous; Male; Methotrexate; Pilot Projects; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Teniposide; United States | 1990 |
Biochemical interactions between methotrexate and 1-beta-D-arabinofuranosylcytosine in hematopoietic cells of children: a Pediatric Oncology Group study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cells, Cultured; Child; Cytarabine; DNA, Neoplasm; Drug Evaluation; Drug Synergism; Hematopoietic Stem Cells; Humans; Leucovorin; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction | 1990 |
Treatment of adult acute lymphoblastic leukaemia.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Combinations; Drug Evaluation; Humans; Mercaptopurine; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; South Africa; Vincristine | 1990 |
[Adult acute lymphoblastic leukemia: preliminary results of the LAL-86 protocol].
Topics: Actuarial Analysis; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Carmustine; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Lymphoma, Non-Hodgkin; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Spain; Survival Rate; Teniposide; Thioguanine; Vincristine | 1990 |
Bone marrow transplantation for the treatment of leukaemia-results of the Munich Cooperative Group.
Topics: Adolescent; Adult; Bone Marrow Transplantation; Carmustine; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Female; Germany, West; Graft vs Host Disease; Humans; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Middle Aged; Multicenter Studies as Topic; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Survival Rate; Whole-Body Irradiation | 1989 |
[Intensive induction and early consolidation of acute lymphoid leukemia in the adult. A pilot study of feasibility and long-term development].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cytarabine; Daunorubicin; Doxorubicin; Female; Humans; Male; Middle Aged; Multicenter Studies as Topic; Pilot Projects; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Remission Induction; Vincristine | 1989 |
Treatment of childhood acute lymphoblastic leukemia with protocol TCL821: a report of Taiwan Children's Cancer Study Group.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Dexamethasone; Doxorubicin; Evaluation Studies as Topic; Female; Follow-Up Studies; Humans; Hydrocortisone; Infant; Male; Mercaptopurine; Methotrexate; Multicenter Studies as Topic; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction; Taiwan; Vincristine | 1989 |
Idarubicin in acute leukaemia. GIMEMA Group.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Female; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Multicenter Studies as Topic; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1989 |
Intensive therapy for children with acute lymphoblastic leukaemia and unfavourable presenting features. Early conclusions of study CCG-106 by the Childrens Cancer Study Group.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Drug Combinations; Female; Humans; Infant; Male; Meningeal Neoplasms; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Radiotherapy Dosage; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination | 1988 |
A comparison of two regimens for high-risk acute lymphocytic leukemia in childhood. A Pediatric Oncology Group Study.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Humans; Hydrocortisone; Infant; Infant, Newborn; Infections; Mercaptopurine; Methotrexate; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prospective Studies; Random Allocation; Remission Induction; Vincristine | 1989 |
Idarubicin in acute leukemias: experience of the Italian Cooperative Group GIMEMA.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Female; Humans; Idarubicin; Leukemia; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Random Allocation; Remission Induction | 1989 |
Isolated central nervous system relapse in acute lymphocytic leukemia (ALL) in children. Experiences of the Swiss Pediatric Oncology Group (SPOG/SAKK) 1976-1986.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Diseases; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Female; Humans; Hydrocortisone; Infant; Injections, Intravenous; Injections, Spinal; Male; Methotrexate; Multicenter Studies as Topic; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Switzerland | 1988 |
Randomized multicentric Italian study on two treatment regimens for marrow relapse in childhood acute lymphoblastic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Combinations; Humans; Italy; Life Tables; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Survival Rate; Thioguanine; Vincristine | 1986 |
503 other study(ies) available for cytarabine and Acute Lymphoid Leukemia
Article | Year |
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Quinacrine-CASIN combination overcomes chemoresistance in human acute lymphoid leukemia.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carbazoles; Cell Line, Tumor; Cytarabine; Drug Resistance, Neoplasm; Female; Humans; Male; Mice; Mice, Transgenic; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Primary Cell Culture; Quinacrine; Xenograft Model Antitumor Assays | 2021 |
The incidence of symptomatic osteonecrosis is similar between Japanese children and children in Western countries with acute lymphoblastic leukaemia treated with a Berlin-Frankfurt-Münster (BFM)95-based protocol.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Incidence; Infant; Japan; Male; Mercaptopurine; Osteonecrosis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prednisone; Retrospective Studies; Vincristine | 2022 |
Cerebrospinal fluid flow cytometry and risk of central nervous system relapse after hyperCVAD in adults with acute lymphoblastic leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System; Cytarabine; Flow Cytometry; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence | 2022 |
Upper gastrointestinal bleeding secondary to toxicity by anthracyclines, cytarabine and methotrexate in a patient with acute lymphoblastic leukemia.
Topics: Acute Disease; Anthracyclines; Cytarabine; Gastrointestinal Hemorrhage; Humans; Male; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Ulcer | 2022 |
[Mechanism of miR-155 Promoting Drug Resistance in Childhood Acute Lymphoblastic Leukemia by Regulating Wnt/β-Catenin Signaling Pathway].
Topics: Apoptosis; beta Catenin; Cell Line, Tumor; Cell Proliferation; Child; Cytarabine; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Wnt Signaling Pathway | 2022 |
Astaxanthin decreases the growth-inhibitory dose of cytarabine and inflammatory response in the acute lymphoblastic leukemia cell line NALM-6.
Topics: Apoptosis; Cell Line; Cytarabine; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Xanthophylls | 2022 |
The diagnostic dilemma of idiopathic intracranial hypertension in a child with acute lymphoblastic leukemia: COVID-19 or cytosine arabinoside?
Topics: Child; COVID-19; Cytarabine; Headache; Humans; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pseudotumor Cerebri; SARS-CoV-2 | 2022 |
Molecular Characterization of the Response to Conventional Chemotherapeutics in Pro-B-ALL Cell Lines in Terms of Tumor Relapse.
Topics: Antineoplastic Agents; Cell Line; Cytarabine; Humans; MicroRNAs; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence | 2022 |
Long-term results of the treatment of adolescents and adults with acute lymphoblastic leukemia with a pediatric-inspired regimen delivered on an outpatient basis: A single institution experience.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Etoposide; Humans; Mercaptopurine; Methotrexate; Outpatients; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Vincristine | 2022 |
Neutropenic fever of unknown origin and disseminated granulomatous disease in a patient with acute lymphoblastic leukemia.
Topics: Adolescent; Cyclophosphamide; Cytarabine; Fever of Unknown Origin; Granuloma; Humans; Male; Mercaptopurine; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2022 |
Outcomes with high dose cytarabine and mitoxantrone induction for adults with mixed phenotype acute leukemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Phenotype; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies | 2023 |
Invasive mucormycosis during treatment for acute lymphoblastic leukaemia-successful management of two life-threatening diseases.
Topics: Amphotericin B; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Humans; Invasive Fungal Infections; Lung Diseases, Fungal; Male; Mercaptopurine; Methotrexate; Mucorales; Mucormycosis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Triazoles; Vincristine | 2020 |
A New Conditioning Regimen Can Significantly Promote Post-Transplant Immune Reconstitution and Improve the Outcome of Umbilical Cord Blood Transplantation for Patients.
Topics: Adult; Anemia, Aplastic; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cord Blood Stem Cell Transplantation; Cyclophosphamide; Cytarabine; Female; Graft Survival; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Humans; Immune Reconstitution; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Primary Immunodeficiency Diseases; Semustine; Survival Analysis; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Unrelated Donors; Vidarabine | 2019 |
Activated stromal cells transfer mitochondria to rescue acute lymphoblastic leukemia cells from oxidative stress.
Topics: Adult; Aged; Animals; Antineoplastic Agents; Cell Line, Tumor; Cells, Cultured; Coculture Techniques; Cytarabine; Daunorubicin; Female; Humans; Male; Mesenchymal Stem Cells; Mice; Middle Aged; Mitochondria; Oxidative Stress; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Young Adult | 2019 |
An 1H NMR study of the cytarabine degradation in clinical conditions to avoid drug waste, decrease therapy costs and improve patient compliance in acute leukemia.
Topics: Antimetabolites, Antineoplastic; Chromatography, High Pressure Liquid; Cost Savings; Cytarabine; Drug Costs; Drug Stability; Drug Storage; Humans; Leukemia, Myeloid, Acute; Medication Adherence; Nuclear Magnetic Resonance, Biomolecular; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Solutions | 2020 |
FLAG With Bortezomib in Childhood Relapsed/Refractory Leukemia: Remission Induction With Limited Toxicity in the Era of Multidrug-resistant Bacteria.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bortezomib; Child; Child, Preschool; Cytarabine; Drug Resistance, Multiple, Bacterial; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Retrospective Studies; Vidarabine | 2021 |
Sgc8 aptamer targeted glutathione-responsive nanoassemblies containing Ara-C prodrug for the treatment of acute lymphoblastic leukemia.
Topics: Animals; Antineoplastic Agents; Apoptosis; Biocompatible Materials; Cell Line, Tumor; Cytarabine; Drug Delivery Systems; Glutathione; Hemolysis; Humans; MCF-7 Cells; Mice; Mice, Nude; Micelles; Neoplasm Transplantation; Particle Size; Polyesters; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Serum Albumin, Bovine | 2019 |
Optimizing the use of the hyperCVAD regimen: Clinical vignettes and practical management.
Topics: Age Factors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Constipation; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Drug Monitoring; Fusion Proteins, bcr-abl; Genetic Predisposition to Disease; Humans; Injections, Spinal; Intercellular Signaling Peptides and Proteins; Kidney; Methotrexate; Ophthalmic Solutions; Peripheral Nervous System Diseases; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Protein-Tyrosine Kinases; Vincristine | 2020 |
Permanent insulin-dependent diabetes mellitus in a patient with acute lymphoblastic leukemia.
Topics: Adolescent; Adrenal Cortex Hormones; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Blood Glucose; Cyclophosphamide; Cytarabine; Dexamethasone; Diabetes Mellitus, Type 1; Doxorubicin; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Thioguanine; Treatment Outcome; Vincristine | 2020 |
Reduced-dose intensity therapy for pediatric lymphoblastic leukemia: long-term results of the Recife RELLA05 pilot study.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Infant; Male; Mercaptopurine; Methotrexate; Neoplasm, Residual; Pilot Projects; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Survival Rate; Vincristine | 2020 |
Implementation of RNA sequencing and array CGH in the diagnostic workflow of the AIEOP-BFM ALL 2017 trial on acute lymphoblastic leukemia.
Topics: Abnormal Karyotype; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Comparative Genomic Hybridization; Cyclophosphamide; Cytarabine; Daunorubicin; Genes, Neoplasm; Humans; Ikaros Transcription Factor; In Situ Hybridization, Fluorescence; Mercaptopurine; Methotrexate; Neoplasm Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prospective Studies; Risk Factors; RNA, Messenger; RNA, Neoplasm; Sequence Analysis, RNA; Transcriptome; Vincristine; Workflow | 2020 |
T Regulatory Cell Frequency During Maintenance Phase Chemotherapy for Pediatric Acute Lymphoblastic Leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Etoposide; Female; Humans; Hydrocortisone; Maintenance Chemotherapy; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; T-Lymphocytes, Regulatory; Vincristine | 2020 |
Drug-induced aseptic meningitis in a Ph+ ALL patient with meningeal involvement.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Meningitis, Aseptic; Methotrexate; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2020 |
Salvage therapy with decitabine in combination with granulocyte colony-stimulating factor, low-dose cytarabine, and aclarubicin in patients with refractory or relapsed early T-cell precursor acute lymphoblastic leukemia.
Topics: Aclarubicin; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Decitabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Salvage Therapy; Survival Analysis | 2020 |
Clinicoepidemiologic Profile and Outcome Predicted by Minimal Residual Disease in Children With Mixed-phenotype Acute Leukemia Treated on a Modified MCP-841 Protocol at a Tertiary Cancer Institute in India.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Chlorambucil; Cytarabine; Female; Follow-Up Studies; Humans; India; Male; Mitoxantrone; Neoplasm, Residual; Phenotype; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Survival Rate | 2020 |
Acute lymphoblastic leukemia-like treatment regimen provides better response in mixed phenotype acute leukemia: a comparative study between adults and pediatric MPAL patients.
Topics: Adolescent; Adult; Age of Onset; Aged; Antineoplastic Combined Chemotherapy Protocols; Antineoplastic Protocols; Child; Child, Preschool; Cohort Studies; Cytarabine; Daunorubicin; Egypt; Etoposide; Female; Humans; Incidence; Induction Chemotherapy; Infant; Leukemia, Biphenotypic, Acute; Maintenance Chemotherapy; Male; Middle Aged; Phenotype; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Treatment Outcome; Young Adult | 2021 |
BACH2-mediated FOS confers cytarabine resistance via stromal microenvironment alterations in pediatric ALL.
Topics: Animals; Antimetabolites, Antineoplastic; Basic-Leucine Zipper Transcription Factors; Cell Proliferation; Child; Child, Preschool; Cytarabine; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Leukemic; Gene Knockdown Techniques; Humans; Infant; Male; Mesenchymal Stem Cells; Mice; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Primary Cell Culture; Proto-Oncogene Proteins c-fos; Tumor Cells, Cultured; Tumor Microenvironment; Xenograft Model Antitumor Assays | 2021 |
Reduced intensity of early intensification does not increase the risk of relapse in children with standard risk acute lymphoblastic leukemia - a multi-centric clinical study of GD-2008-ALL protocol.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Humans; Infant; Male; Mercaptopurine; Neoplasm Recurrence, Local; Neoplasm, Residual; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Remission Induction; Retrospective Studies; Survival Rate | 2021 |
Outcomes and prognostic factors in adolescents and young adults with ALL treated with a modified BFM-90 protocol.
Topics: Adolescent; Adult; Child; Cytarabine; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Stem Cell Transplantation; Young Adult | 2021 |
Oxidative phosphorylation enhances the leukemogenic capacity and resistance to chemotherapy of B cell acute lymphoblastic leukemia.
Topics: Animals; Cytarabine; Cytidine Deaminase; Mice; Mice, Transgenic; Oxidative Phosphorylation; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2021 |
Exploiting the reactive oxygen species imbalance in high-risk paediatric acute lymphoblastic leukaemia through auranofin.
Topics: Animals; Auranofin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Child; Cytarabine; Drug Screening Assays, Antitumor; Drug Synergism; Female; High-Throughput Screening Assays; Humans; Mice; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Reactive Oxygen Species; Small Molecule Libraries; Xenograft Model Antitumor Assays | 2021 |
Successful use of trametinib and dasatinib combined with chemotherapy in the treatment of Ph-positive B-cell acute lymphoblastic leukemia: A case report.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Azathioprine; Child; Consolidation Chemotherapy; Cyclophosphamide; Cytarabine; Dasatinib; Humans; Maintenance Chemotherapy; Male; Pancreatitis; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyridones; Pyrimidinones; Treatment Outcome | 2021 |
Comprehensive analysis of dose intensity of acute lymphoblastic leukemia chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Escherichia coli; Humans; Mercaptopurine; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2022 |
Cytarabine and EIP co-administration synergistically reduces viability of acute lymphoblastic leukemia cells with high ERG expression.
Topics: Animals; Apoptosis; Biomarkers, Tumor; Cell Cycle; Cell Movement; Cell Proliferation; Cytarabine; Drug Therapy, Combination; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Inbred NOD; Mice, SCID; Peptide Fragments; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Transcriptional Regulator ERG; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2021 |
Pre-conditioning intervention in patients with relapsed or refractory acute lymphoblastic leukemia who underwent allogeneic hematopoietic cell transplantation: a KSGCT multicenter retrospective analysis.
Topics: Adolescent; Adult; Aged; Allografts; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Retrospective Studies; Transplantation Conditioning; Vincristine; Young Adult | 2021 |
Increased non-relapse mortality due to high-dose cytarabine plus CY/TBI in BMT/PBSCT for acute lymphoblastic leukaemia in adults.
Topics: Adolescent; Adult; Aged; Bone Marrow Transplantation; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Female; Humans; Japan; Kaplan-Meier Estimate; Male; Middle Aged; Peripheral Blood Stem Cell Transplantation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Recurrence; Registries; Transplantation Conditioning; Whole-Body Irradiation; Young Adult | 2017 |
Prognostic impact of IKZF1 deletions in association with vincristine-dexamethasone pulses during maintenance treatment of childhood acute lymphoblastic leukemia on trial ALL-BFM 95.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Gene Deletion; Humans; Ikaros Transcription Factor; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Treatment Outcome; Vincristine | 2017 |
Exacerbation of allopurinol-induced drug reaction with eosinophilia and systemic symptoms by teicoplanin: A case report.
Topics: Allopurinol; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Hypersensitivity Syndrome; Female; Gout Suppressants; Granulocyte Colony-Stimulating Factor; Humans; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Teicoplanin; Vidarabine | 2017 |
The novel phospholipid mimetic KPC34 is highly active against preclinical models of Philadelphia chromosome positive acute lymphoblastic leukemia.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cytarabine; Deoxycytidine; DNA Damage; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Gemcitabine; Glycerophosphates; Humans; Mice, Inbred C57BL; Mice, Transgenic; Neoplasm Transplantation; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinase C; Random Allocation; Tumor Burden | 2017 |
Recurrent urinary tract infections and low secretory IgA following CD19-directed CAR T-cell therapy for relapsed acute lymphoblastic leukemia.
Topics: Antigens, CD19; Antimetabolites, Antineoplastic; B-Lymphocytes; Bacteriuria; Child; Clofarabine; Cytarabine; Escherichia coli; Escherichia coli Infections; Female; Humans; Immunoglobulin A, Secretory; Immunoglobulin G; Immunoglobulin M; Immunotherapy, Adoptive; Lymphocyte Count; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proteus Infections; Proteus mirabilis; Urinary Tract Infections | 2018 |
Efficacy and safety of G-CSF, low-dose cytarabine and aclarubicin in combination with l-asparaginase, prednisone in the treatment of refractory or relapsed acute lymphoblastic leukemia.
Topics: Aclarubicin; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Disease-Free Survival; Female; Granulocyte Colony-Stimulating Factor; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Salvage Therapy; Treatment Outcome; Young Adult | 2017 |
Changes in cognition and dendritic complexity following intrathecal methotrexate and cytarabine treatment in a juvenile murine model.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cognition; Cytarabine; Dendrites; Hippocampus; Injections, Spinal; Leukocytes; Male; Methotrexate; Mice, Inbred C57BL; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Spatial Memory | 2018 |
Flow cytometric analysis of cerebrospinal fluid in adult patients with acute lymphoblastic leukemia during follow-up.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System; Cytarabine; Dexamethasone; Female; Flow Cytometry; Hematopoietic Stem Cell Transplantation; Humans; Male; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Survival Analysis; Transplantation, Homologous; Whole-Body Irradiation | 2018 |
Crocin improves the proliferation and cytotoxic function of T cells in children with acute lymphoblastic leukemia.
Topics: Apoptosis; Carotenoids; CD4-CD8 Ratio; Cell Proliferation; Child; Comet Assay; Cytarabine; Cytotoxicity, Immunologic; DNA Damage; DNA Repair; Humans; Interleukin-2; Interleukin-4; Precursor Cell Lymphoblastic Leukemia-Lymphoma; T-Lymphocytes | 2018 |
[Intravenous chemotherapy at home: A pediatric monocentric experience].
Topics: Antineoplastic Agents; Child; Cytarabine; Eye Neoplasms; Female; Glioma; Health Services Accessibility; Hematologic Neoplasms; Home Care Services, Hospital-Based; Humans; Injections, Intravenous; Male; Neoplasms; Oncology Nursing; Pediatric Nursing; Pediatricians; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Time Factors; Vinblastine | 2018 |
Evidence of cognitive flexibility deficits and impaired emotion regulation in childhood survivors of acute lymphoblastic leukaemia: Findings from task switching study.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cancer Survivors; Case-Control Studies; Child; Cognition; Cognitive Dysfunction; Cytarabine; Emotions; Female; Humans; Hydrocortisone; Infusions, Spinal; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Self-Control; Task Performance and Analysis | 2018 |
[Establishment of Drug-resistant Acute Lymphoblastic Leukemic Cell Lines and Their Resistance Mechanism].
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line; Cytarabine; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2018 |
[Spinal subacute combined degeneration after intrathecal chemotherapy. Report of two cases].
Topics: Adolescent; Antimetabolites, Antineoplastic; Cytarabine; Fatal Outcome; Female; Humans; Injections, Spinal; Magnetic Resonance Imaging; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Subacute Combined Degeneration | 2018 |
[Acute Lymphoblastic Leukemia - Diagnostics, Subgroups and Therapies].
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anthracyclines; Antineoplastic Agents; Asparaginase; Child; Child, Preschool; Chromosome Aberrations; Cyclophosphamide; Cytarabine; Dexamethasone; Female; Humans; Immunotherapy; Incidence; Infant; Male; Mercaptopurine; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Risk Factors; Vincristine; Young Adult | 2018 |
Early T-cell precursor lymphoblastic leukaemia: response to FLAG-IDA and high-dose cytarabine with sorafenib after initial refractoriness.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sorafenib; Treatment Outcome; Vidarabine | 2019 |
Chemosensitivity is differentially regulated by the SDF-1/CXCR4 and SDF-1/CXCR7 axes in acute lymphoblastic leukemia with MLL gene rearrangements.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Chemokine CXCL12; Cytarabine; Drug Resistance, Neoplasm; Gene Rearrangement; Histone-Lysine N-Methyltransferase; Humans; Myeloid-Lymphoid Leukemia Protein; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, CXCR; Receptors, CXCR4 | 2018 |
FLAG/FLAG-IDA regimen for children with relapsed/refractory acute leukemia in the era of targeted novel therapies.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Infant; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Retrospective Studies; Vidarabine | 2019 |
Cyr61 decreases Cytarabine chemosensitivity in acute lymphoblastic leukemia cells via NF-κB pathway activation.
Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Apoptosis; Bone Marrow; Cell Line, Tumor; Child; Cysteine-Rich Protein 61; Cytarabine; Female; Gene Expression Regulation, Leukemic; Humans; Male; NF-kappa B; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proto-Oncogene Proteins c-bcl-2; Young Adult | 2019 |
Case report of neurotoxicity with blinatumomab and concurrent intrathecal chemotherapy in second relapse of acute lymphoblastic leukemia with central nervous system disease.
Topics: Adult; Antibodies, Bispecific; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Diseases; Cytarabine; Humans; Hydrocortisone; Male; Methotrexate; Neurotoxicity Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence | 2019 |
Romidepsin enhances the efficacy of cytarabine
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Proliferation; Cytarabine; Depsipeptides; Drug Synergism; Female; Gene Rearrangement; Histone Deacetylase Inhibitors; Histone Deacetylases; Histone-Lysine N-Methyltransferase; Humans; Infant; Mice; Mice, Inbred NOD; Mice, SCID; Myeloid-Lymphoid Leukemia Protein; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2019 |
Visualization of Vertebral Body Deformities in Childhood by MRI in a Boy with ALL.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Density; Bone Marrow; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Fractures, Compression; Humans; Image Enhancement; Magnetic Resonance Imaging; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Spinal Fractures; Spine; Vincristine | 2019 |
The MitoNEET Ligand NL-1 Mediates Antileukemic Activity in Drug-Resistant B-Cell Acute Lymphoblastic Leukemia.
Topics: Antineoplastic Agents; Autophagy; Cell Line, Tumor; Chemotaxis; Cytarabine; Drug Discovery; Drug Resistance, Neoplasm; Humans; Ligands; Mitochondrial Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence | 2019 |
Spinal Cord Toxicity from Intrathecal Chemotherapy: A Case with Clinicopathologic Correlation.
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dendritic Cells; Electrodiagnosis; Evoked Potentials, Somatosensory; Humans; Injections, Spinal; Magnetic Resonance Imaging; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Spinal Cord Diseases; Spinal Cord Neoplasms; Treatment Outcome | 2019 |
Efficacy and safety of a bortezomib and reduced-intensity cytarabine-based protocol, TMC ALLR1, for relapsed childhood ALL in India.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bortezomib; Child; Child, Preschool; Cytarabine; Disease-Free Survival; Female; Humans; India; Infant; Male; Neoplasm, Residual; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Survival Rate | 2019 |
Inotuzumab ozogamicin, a nonchemotherapy option for relapsed acute lymphoblastic leukemia.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Bispecific; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Cyclophosphamide; Cytarabine; Dexamethasone; Humans; Inotuzumab Ozogamicin; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Salvage Therapy; Vascular Diseases | 2019 |
Long-term outcomes of modified BFM-95 regimen in adults with newly diagnosed standard-risk acute lymphoblastic leukemia: a retrospective single-center study.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Asian People; Asparaginase; Cohort Studies; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Maintenance Chemotherapy; Male; Mercaptopurine; Methotrexate; Neoplasm, Residual; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction; Retrospective Studies; Risk; Time Factors; Treatment Outcome; Vincristine | 2019 |
[Kaposiform haemangioendothelioma associated with B-cell acute lymphoblastic leukemia].
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Biopsy; Combined Modality Therapy; Cord Blood Stem Cell Transplantation; Cyclophosphamide; Cytarabine; Diagnostic Errors; Hemangioendothelioma; Hemangioma; Humans; Infant, Newborn; Kasabach-Merritt Syndrome; Leukemia, B-Cell; Male; Mercaptopurine; Methotrexate; Neoplasms, Multiple Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction; Skin Neoplasms; Transplantation, Homologous | 2013 |
Acral erythema worsened by intravenous infusions of cyclosporin.
Topics: Adult; Antineoplastic Agents; Cyclosporine; Cytarabine; Drug Eruptions; Erythema; Graft vs Host Disease; Humans; Infusions, Intravenous; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2013 |
Adhesion to osteopontin in the bone marrow niche regulates lymphoblastic leukemia cell dormancy.
Topics: Adult; Animals; Antibodies, Neutralizing; Antimetabolites, Antineoplastic; Blast Crisis; Bone Marrow; Cell Adhesion; Child; Child, Preschool; Cytarabine; Drug Resistance, Neoplasm; Female; Humans; Ki-67 Antigen; Male; Mice; Mice, SCID; Neoplasm Transplantation; Neoplasm, Residual; Osteoblasts; Osteopontin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Signal Transduction; Transplantation, Heterologous; Tumor Microenvironment | 2013 |
Effects of early chemotherapeutic treatment on learning in adolescent mice: implications for cognitive impairment and remediation in childhood cancer survivors.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cognitive Dysfunction; Cytarabine; Female; Humans; Learning; Male; Methotrexate; Mice; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pregnancy; Survivors | 2013 |
Low-dose cytarabine and aclarubicin combined with granulocyte colony-stimulating factor for the treatment of relapsed or primary refractory acute lymphocytic leukemia: a retrospective study of 25 Chinese patients.
Topics: Aclarubicin; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; China; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Drug Evaluation; Drug Resistance, Neoplasm; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Male; Middle Aged; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Retrospective Studies; Salvage Therapy; Treatment Outcome; Young Adult | 2013 |
The principle and practice of reinduction therapy (in ALL): repetita iuvant!
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Germany; History, 20th Century; History, 21st Century; Humans; Induction Chemotherapy; Medical Oncology; Pediatrics; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Thioguanine; Vincristine | 2013 |
Key treatment questions in childhood acute lymphoblastic leukemia: results in 5 consecutive trials performed by the ALL-BFM study group from 1981 to 2000.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Europe; Germany; History, 20th Century; History, 21st Century; Humans; Medical Oncology; Mercaptopurine; Methotrexate; Pediatrics; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Randomized Controlled Trials as Topic; Vincristine | 2013 |
ALL-REZ BFM--the consecutive trials for children with relapsed acute lymphoblastic leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow; Child; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Disease-Free Survival; Europe; Hematopoietic Stem Cell Transplantation; Humans; Mercaptopurine; Methotrexate; Multicenter Studies as Topic; Neoplasm, Residual; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Randomized Controlled Trials as Topic; Recurrence; Remission Induction; Retreatment; Survival Rate; Vincristine | 2013 |
Detection of MRD may predict the outcome of patients with Philadelphia chromosome-positive ALL treated with tyrosine kinase inhibitors plus chemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Cyclophosphamide; Cytarabine; Dasatinib; Dexamethasone; Doxorubicin; Female; Flow Cytometry; Follow-Up Studies; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Immunoglobulin Heavy Chains; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasm, Residual; Philadelphia Chromosome; Piperazines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Pyrimidines; Real-Time Polymerase Chain Reaction; Remission Induction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Survival Rate; Thiazoles; Vincristine; Young Adult | 2013 |
[Liposomal cytarabine in prophylaxis of the central nervous system involvement in rare aggresive lymphomas].
Topics: Adult; Antimetabolites, Antineoplastic; Burkitt Lymphoma; Central Nervous System Neoplasms; Cytarabine; Drug Carriers; Female; Follow-Up Studies; Humans; Liposomes; Lymphoma, T-Cell, Peripheral; Male; Middle Aged; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Young Adult | 2013 |
Safety and tolerability of intrathecal liposomal cytarabine as central nervous system prophylaxis in patients with acute lymphoblastic leukemia.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Cytarabine; Female; Follow-Up Studies; Humans; Injections, Spinal; Liposomes; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome; Young Adult | 2014 |
Herpes simplex virus reactivation and disease during treatment for childhood acute lymphoblastic leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bacterial Infections; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Encephalitis, Herpes Simplex; Fatal Outcome; Female; Hematopoietic Stem Cell Transplantation; Herpes Simplex; Humans; Induction Chemotherapy; Infant; Male; Mercaptopurine; Methotrexate; Opportunistic Infections; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Simplexvirus; Stomatitis, Herpetic; Vincristine; Virus Activation | 2014 |
Fludarabine, cytarabine, granulocyte colony-stimulating factor and melphalan (FALG with L-PAM) as a reduced toxicity conditioning regimen in children with acute leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Female; Follow-Up Studies; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Humans; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Male; Melphalan; Neoplasm Recurrence, Local; Postoperative Complications; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Remission Induction; Survival Rate; Transplantation Conditioning; Transplantation, Homologous; Vidarabine; Whole-Body Irradiation | 2014 |
High relapse rate of T cell acute lymphoblastic leukemia in adults treated with Hyper-CVAD chemotherapy in Sweden.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Betamethasone; Cyclophosphamide; Cytarabine; Doxorubicin; Female; Hematopoietic Stem Cell Transplantation; Humans; Male; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Survival Analysis; Sweden; Transplantation, Homologous; Vincristine | 2014 |
The long-term results of childhood acute lymphoblastic leukemia at two centers from Turkey: 15 years of experience with the ALL-BFM 95 protocol.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Evaluation; Follow-Up Studies; Humans; Immunophenotyping; Infant; Kaplan-Meier Estimate; Leukocyte Count; Mercaptopurine; Oncogene Proteins, Fusion; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction; Retrospective Studies; Risk Assessment; Risk Factors; Treatment Outcome; Turkey; Vincristine | 2014 |
Toxicity and efficacy of intrathecal liposomal cytarabine in children with leukemia/lymphoma relapsing in the central nervous system: a retrospective multicenter study.
Topics: Adolescent; Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Child; Child, Preschool; Cytarabine; Female; Humans; Infant; Injections, Spinal; Leukemia, Myeloid, Acute; Liposomes; Lymphoma, Non-Hodgkin; Male; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies | 2015 |
Enhanced skin toxicity associated with the combination of clofarabine plus cytarabine for the treatment of acute leukemia.
Topics: Adenine Nucleotides; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cytarabine; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Retrospective Studies; Skin Diseases | 2014 |
Leukemia propagating cells rebuild an evolving niche in response to therapy.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bone Marrow Cells; Cytarabine; Daunorubicin; Disease Models, Animal; Humans; Mice; Mice, Inbred NOD; Mice, SCID; Neoplastic Stem Cells; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stem Cell Niche; Tumor Microenvironment; Xenograft Model Antitumor Assays | 2014 |
Tumor Lysis Syndrome: An Unreported Complication of Intrathecal Ara-C.
Topics: Adolescent; Antimetabolites, Antineoplastic; Cytarabine; Humans; Injections, Spinal; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Tumor Lysis Syndrome | 2015 |
Liposomal daunorubicin, fludarabine, and cytarabine (FLAD) as bridge therapy to stem cell transplant in relapsed and refractory acute leukemia.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Component Transfusion; Combined Modality Therapy; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Diarrhea; Drug Administration Schedule; Drug Evaluation; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Liposomes; Male; Middle Aged; Neutropenia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proportional Hazards Models; Remission Induction; Retrospective Studies; Salvage Therapy; Vidarabine; Young Adult | 2014 |
Augmented Berlin-Frankfurt-Münster therapy in adolescents and young adults (AYAs) with acute lymphoblastic leukemia (ALL).
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cohort Studies; Consolidation Chemotherapy; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Doxorubicin; Female; Humans; Induction Chemotherapy; Maintenance Chemotherapy; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Thioguanine; Treatment Outcome; Vincristine; Young Adult | 2014 |
Single-unit cord blood transplant for acute lymphoblastic leukemia and lymphoma using an intensified conditioning regimen of total body irradiation, high-dose cytarabine and cyclophosphamide.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cord Blood Stem Cell Transplantation; Cyclophosphamide; Cytarabine; Female; Follow-Up Studies; Humans; Lymphoma; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Retrospective Studies; Survival Analysis; Transplantation Conditioning; Treatment Outcome; Whole-Body Irradiation; Young Adult | 2015 |
Prognostic factors in adolescent and adult patients with acute lymphoblastic leukemia with two protocols of chemotherapy: a cross-sectional study.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Consolidation Chemotherapy; Cross-Sectional Studies; Cyclophosphamide; Cytarabine; Female; Humans; Induction Chemotherapy; Male; Mercaptopurine; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Retrospective Studies; Treatment Outcome; Vincristine; Young Adult | 2015 |
Clinical efficacy of mitoxantrone and Ara-C with or without etoposide salvage chemotherapy in adult patients with relapsed or refractory acute lymphoblastic leukemia: retrospective multicenter study of the Korean Adult ALL Working Party.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Humans; Male; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Retrospective Studies; Salvage Therapy; Treatment Outcome; Young Adult | 2015 |
Efficacy of CPX-351, (cytarabine:daunorubicin) liposome injection, against acute lymphoblastic leukemia (ALL) xenograft models of the Pediatric Preclinical Testing Program.
Topics: Adolescent; Animals; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Female; Humans; Liposomes; Male; Maximum Tolerated Dose; Mice; Mice, Inbred NOD; Mice, SCID; Pediatrics; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tissue Distribution; Treatment Outcome; Xenograft Model Antitumor Assays | 2015 |
Idiopathic Hyperammonemia That Developed During Initial Treatment With Steroid in a Patient With Newly Diagnosed Leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Hydrocortisone; Hyperammonemia; Lactulose; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis | 2015 |
Plerixafor as a chemosensitizing agent in pediatric acute lymphoblastic leukemia: efficacy and potential mechanisms of resistance to CXCR4 inhibition.
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzylamines; Cell Adhesion Molecules; Cell Line, Tumor; Chemokine CXCL12; Chemotaxis; Coculture Techniques; Cyclams; Cytarabine; Heterocyclic Compounds; Heterografts; Humans; Infant; Infant, Newborn; Integrin alpha4beta1; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Transplantation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, CXCR; Receptors, CXCR4; Up-Regulation | 2014 |
Variegated clonality and rapid emergence of new molecular lesions in xenografts of acute lymphoblastic leukemia are associated with drug resistance.
Topics: Animals; Antineoplastic Agents; Biopsy; Clone Cells; Cytarabine; Deoxycytidine Kinase; Dexamethasone; Disease Progression; DNA, Neoplasm; Drug Resistance, Neoplasm; Female; Gene Dosage; Heterografts; Humans; Male; Methotrexate; Mice; Mice, Inbred NOD; Mice, SCID; Mutation; Neoplasm Proteins; Neoplasm Transplantation; Neoplastic Stem Cells; Peptide Synthases; Polymorphism, Single Nucleotide; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Radiation Chimera; Sequence Analysis, DNA; Vincristine | 2015 |
Diffuse cerebral vasospasm with infarct after intrathecal cytarabine in childhood leukemia.
Topics: Antimetabolites, Antineoplastic; Cerebral Infarction; Child; Cytarabine; Female; Humans; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Vasospasm, Intracranial | 2014 |
Clinical features and prognostic significance of TCF3-PBX1 fusion gene in Chinese children with acute lymphoblastic leukemia by using a modified ALL-BFM-95 protocol.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asian People; Asparaginase; Child; Child, Preschool; China; Cyclophosphamide; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Infant; Karyotyping; Male; Mercaptopurine; Oncogene Proteins, Fusion; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Retrospective Studies; Vincristine | 2015 |
Impact of single nucleotide polymorphisms of cytarabine metabolic genes on drug toxicity in childhood acute lymphoblastic leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Deoxycytidine Kinase; Female; Genes, Neoplasm; Humans; Infant; Male; Neoplasm Proteins; Polymorphism, Single Nucleotide; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Risk Factors | 2015 |
A novel mechanism of toxic injury to the Papez circuit from chemotherapy.
Topics: Adolescent; Brain; Cytarabine; Drug Delivery Systems; Humans; Magnetic Resonance Imaging; Memory Disorders; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2015 |
[Dasatinib-related pneumonia? An example of pharmacovigilance survey].
Topics: Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Cyclophosphamide; Cytarabine; Dasatinib; Dexamethasone; Doxorubicin; Filgrastim; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Methotrexate; Middle Aged; Pharmacovigilance; Pneumonia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinase Inhibitors; Pyrimidines; Recombinant Proteins; Thiazoles; Tomography, X-Ray Computed; Vincristine | 2015 |
Efficacy of low-dose cytarabine and aclarubicin in combination with granulocyte colony-stimulating factor (CAG regimen) compared to Hyper-CVAD regimen as salvage chemotherapy in relapsed/refractory Philadelphia chromosome-negative acute lymphoblastic leuk
Topics: Aclarubicin; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Humans; Male; Middle Aged; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Remission Induction; Retrospective Studies; Salvage Therapy; Survival Rate; Vincristine; Young Adult | 2015 |
Myelopathy following intrathecal chemotherapy in adults: a single institution experience.
Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Cytarabine; Female; Humans; Injections, Spinal; Leukemia, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Myelin Basic Protein; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Spinal Cord; Spinal Cord Diseases | 2015 |
Two cases of cytarabine syndrome successfully resolved by desensitization.
Topics: Aged; Antimetabolites, Antineoplastic; Chills; Cytarabine; Desensitization, Immunologic; Drug-Related Side Effects and Adverse Reactions; Female; Fever; Humans; Hypotension; Leukemia, Myeloid, Acute; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Shivering; Syndrome | 2015 |
Survival of Mexican Children with Acute Lymphoblastic Leukaemia under Treatment with the Protocol from the Dana-Farber Cancer Institute 00-01.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Disease-Free Survival; Female; Humans; Infant; Male; Methotrexate; Mexico; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Risk Factors; Treatment Outcome; United States; Vincristine | 2015 |
Increasing aclarubicin dose in low-dose cytarabine and aclarubicin in combination with granulocyte colony-stimulating factor (CAG regimen) is efficacious as salvage chemotherapy for relapsed/refractory mixed-phenotype acute leukemia.
Topics: Aclarubicin; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Recurrence; Retrospective Studies; Salvage Therapy; Treatment Outcome; Vincristine; Young Adult | 2015 |
The potential of clofarabine in MLL-rearranged infant acute lymphoblastic leukaemia.
Topics: Acid Anhydride Hydrolases; Adenine Nucleotides; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Cell Line, Tumor; Cell Survival; Clofarabine; Cytarabine; DNA Methylation; Dose-Response Relationship, Drug; Drug Synergism; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gene Rearrangement; Histone-Lysine N-Methyltransferase; Humans; Infant; Inhibitory Concentration 50; Myeloid-Lymphoid Leukemia Protein; Neoplasm Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Promoter Regions, Genetic; Tumor Cells, Cultured | 2015 |
Is a New Protocol for Acute Lymphoblastic Leukemia Research or Standard Therapy?
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Clinical Protocols; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Evidence-Based Medicine; Humans; Leucovorin; Mercaptopurine; Methotrexate; Netherlands; Polyethylene Glycols; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Risk Assessment; Therapeutic Human Experimentation; United States; Vincristine | 2015 |
The combination effects of bendamustine with antimetabolites against childhood acute lymphoblastic leukemia cells.
Topics: Adenine Nucleotides; Antimetabolites; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Bendamustine Hydrochloride; Cell Line, Tumor; Cell Proliferation; Child; Cladribine; Clofarabine; Cytarabine; Drug Administration Schedule; Drug Synergism; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Vidarabine | 2016 |
[Clinical and Prognostic analysis of 43 Children with Mature B-cell Non-Hodgkin's Lymphoma/Acute Lymphoblastic Leukemia].
Topics: Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Child; Cyclophosphamide; Cytarabine; Disease-Free Survival; Doxorubicin; Etoposide; Female; Humans; Hydrocortisone; Leucovorin; Logistic Models; Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Multivariate Analysis; Neoplasm Staging; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Retrospective Studies; Survival Rate; Vincristine | 2016 |
Dose-reduced combination of mitoxantrone, etoposide, and cytarabine (miniMEC) for relapsed and refractory acute leukemia.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Retreatment; Treatment Outcome; Young Adult | 2016 |
[The curative efficacy of unrelated umbilical cord blood stem cells transplantation in intensified myeloablative conditioned patients with acute lymphoblastic leukemia].
Topics: Adolescent; Adult; Busulfan; Child; Child, Preschool; Cord Blood Stem Cell Transplantation; Cyclophosphamide; Cytarabine; Disease-Free Survival; Female; Fetal Blood; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Incidence; Male; Middle Aged; Mycophenolic Acid; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Retrospective Studies; Survival Rate; Transplantation Conditioning; Treatment Outcome; Vidarabine; Young Adult | 2016 |
Impact of conditioning intensity in T-replete haplo-identical stem cell transplantation for acute leukemia: a report from the acute leukemia working party of the EBMT.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Disease-Free Survival; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Male; Melphalan; Middle Aged; Multivariate Analysis; Mycophenolic Acid; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Transplantation Conditioning; Treatment Outcome | 2016 |
[Treatment of relapsed and refractory acute lymphocytic leukemia by modified CAG regimen].
Topics: Aclarubicin; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence | 2016 |
Impact of complete molecular response on survival in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Dexamethasone; Disease-Free Survival; Female; Follow-Up Studies; Fusion Proteins, bcr-abl; Humans; Infant; Male; Methotrexate; Neoplasm, Residual; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Survival Rate; Vincristine | 2016 |
FLT3 is implicated in cytarabine transport by human equilibrative nucleoside transporter 1 in pediatric acute leukemia.
Topics: Adolescent; Apoptosis; Biological Transport; Cell Line, Tumor; Child; Child, Preschool; Cytarabine; DNA Mutational Analysis; Equilibrative Nucleoside Transporter 1; Equilibrative-Nucleoside Transporter 2; Female; fms-Like Tyrosine Kinase 3; Gene Expression Regulation, Leukemic; Histone-Lysine N-Methyltransferase; Humans; Infant; Infant, Newborn; Male; Mutation; Myeloid-Lymphoid Leukemia Protein; Nucleoside Transport Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Staurosporine | 2016 |
Extensive cardiac infiltration in acute T-cell lymphoblastic leukemia: occult extra-medullary relapse and remission after salvage chemotherapy.
Topics: Adult; Arabinonucleosides; Cytarabine; Diplopia; Humans; Hypertrophy, Left Ventricular; Leukemic Infiltration; Male; Myocardium; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Salvage Therapy; Stem Cell Transplantation; Transplantation, Homologous | 2017 |
High-dose cytarabine added to CY/TBI improves the prognosis of cord blood transplantation for acute lymphoblastic leukemia in adults: a retrospective cohort study.
Topics: Adolescent; Adult; Bone Marrow Transplantation; Cord Blood Stem Cell Transplantation; Cyclophosphamide; Cytarabine; Female; Fetal Blood; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Peripheral Blood Stem Cell Transplantation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Proportional Hazards Models; Recurrence; Retrospective Studies; Transplantation Conditioning; Treatment Outcome; Whole-Body Irradiation; Young Adult | 2016 |
Prognostic impact of pretreatment cytogenetics in adult Philadelphia chromosome-negative acute lymphoblastic leukemia in the era of minimal residual disease.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cytarabine; Cytodiagnosis; Disease-Free Survival; Doxorubicin; Female; Humans; Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative; Male; Middle Aged; Neoplasm, Residual; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Remission Induction; Treatment Outcome; Vincristine | 2017 |
Low dose triptolide reverses chemoresistance in adult acute lymphoblastic leukemia cells via reactive oxygen species generation and DNA damage response disruption.
Topics: Adolescent; Adult; Aged; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Apoptosis; Caspase 9; Cell Line, Tumor; Cell Proliferation; Checkpoint Kinase 1; Checkpoint Kinase 2; Cytarabine; Diterpenes; DNA Damage; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Epoxy Compounds; Female; Histones; Humans; Inhibitory Concentration 50; Male; Membrane Potential, Mitochondrial; Mice, Inbred NOD; Mice, SCID; Middle Aged; Oxidative Stress; Phenanthrenes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Reactive Oxygen Species; Signal Transduction; Tumor Cells, Cultured; Xenograft Model Antitumor Assays; Young Adult | 2016 |
CPX-351 exhibits potent and direct ex vivo cytotoxicity against AML blasts with enhanced efficacy for cells harboring the FLT3-ITD mutation.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Cytarabine; Daunorubicin; fms-Like Tyrosine Kinase 3; Humans; Inhibitory Concentration 50; Liposomes; Mutation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Cells, Cultured | 2017 |
The central nervous system microenvironment influences the leukemia transcriptome and enhances leukemia chemo-resistance.
Topics: Animals; Antineoplastic Agents; Bone Marrow Cells; Central Nervous System; Coculture Techniques; Cytarabine; Drug Resistance, Neoplasm; Gene Expression Regulation, Leukemic; Humans; Mice; Mice, Inbred NOD; Neoplasm Proteins; Neoplasm Transplantation; Neurons; Pre-B-Cell Leukemia Transcription Factor 1; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Signal Transduction; Transcriptome; Transplantation, Heterologous; Tumor Microenvironment | 2017 |
Pure motor lumbosacral radiculopathy after intrathecal chemotherapy.
Topics: Anti-Inflammatory Agents; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cyclophosphamide; Cytarabine; Dexamethasone; Humans; Hydrocortisone; Injections, Spinal; Lumbar Vertebrae; Magnetic Resonance Imaging; Male; Mercaptopurine; Methotrexate; Middle Aged; Paraparesis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radiculopathy; Sacrum; Spinal Nerve Roots; Vincristine | 2008 |
Dic(9;20)(p13;q11) in childhood acute lymphoblastic leukaemia is related to low cellular resistance to asparaginase, cytarabine and corticosteroids.
Topics: Adolescent; Adrenal Cortex Hormones; Asparaginase; Child; Child, Preschool; Chromosome Aberrations; Chromosomes, Human, Pair 20; Chromosomes, Human, Pair 9; Cytarabine; Drug Resistance, Neoplasm; Humans; Infant; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2009 |
Prophylaxis of central nervous system leukemia: a case of chronic myeloid leukemia with lymphoid blast crisis treated with imatinib mesylate.
Topics: Anti-Inflammatory Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Blast Crisis; Blood Cell Count; Central Nervous System Neoplasms; Chemoprevention; Child; Clinical Protocols; Cytarabine; Drug Therapy, Combination; Female; Humans; Hydrocortisone; Imatinib Mesylate; Injections, Spinal; Methotrexate; Piperazines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyrimidines; Remission Induction | 2008 |
Influence of methylene tetrahydrofolate reductase polymorphisms and coadministration of antimetabolites on toxicity after high dose methotrexate.
Topics: Antimetabolites, Antineoplastic; Child; Child, Preschool; Cytarabine; Female; Humans; Male; Mercaptopurine; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Neutropenia; Polymorphism, Genetic; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Thrombocytopenia | 2008 |
Neurological complications after intrathecal liposomal cytarabine application in patients after allogeneic haematopoietic stem cell transplantation.
Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Cohort Studies; Cytarabine; Female; Hematopoietic Stem Cell Transplantation; Humans; Injections, Spinal; Leukemia, Myeloid, Acute; Liposomes; Lymphoma; Male; Meningitis; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Transplantation, Homologous | 2008 |
Oral mucositis in acute lymphoblastic leukaemia: analysis of 169 paediatric patients.
Topics: Adolescent; Age Factors; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Brazil; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Humans; Infant; Leukocyte Count; Male; Mercaptopurine; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prevalence; Retrospective Studies; Risk Factors; Sex Factors; Stomatitis; Vincristine | 2008 |
Efficacy and safety of intrathecal liposomal cytarabine for the treatment of meningeal relapse in acute lymphoblastic leukemia: experience of two pediatric institutions.
Topics: Adolescent; Antimetabolites, Antineoplastic; Cerebrospinal Fluid; Child; Child, Preschool; Cytarabine; Drug Carriers; Drug Evaluation; Female; Humans; Infant; Injections, Spinal; Liposomes; Male; Meningeal Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Treatment Outcome | 2008 |
Severe neurotoxicities in a case of Charcot-Marie-Tooth disease type 2 caused by vincristine for acute lymphoblastic leukemia.
Topics: Adolescent; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Charcot-Marie-Tooth Disease; Contraindications; Cytarabine; Daunorubicin; Etoposide; Gait Disorders, Neurologic; Humans; Male; Mercaptopurine; Methotrexate; Muscle Weakness; Neural Conduction; Peripheral Nervous System Diseases; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction; Vincristine | 2008 |
Marked increase of normal blast morphologically mimicking leukemic clone in acute lymphoblastic leukemia patient following G-CSF therapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Lymphocyte Activation; Lymphocytes; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recovery of Function; Remission Induction; Time Factors | 2008 |
Practice of central nervous system prophylaxis and treatment in acute leukemias in Spain. Prospective registry study.
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Cytarabine; Drug Therapy, Combination; Female; Humans; Hydrocortisone; Injections, Spinal; Leukemia, Myeloid, Acute; Liposomes; Longitudinal Studies; Male; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Registries; Spain | 2008 |
Fludarabine and cytarabine combined chemotherapy followed by transfusion of donor blood stem cells for treating relapse of acute leukaemia after allogeneic haematopoietic stem cell transplantation.
Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Transplantation, Homologous; Vidarabine | 2008 |
[Relationship between the expression of the genes encoding the key enzymes for cytarabine metabolism and the pharmacokinetics of cytarabine in the treatment of childhood acute leukemia with high-dose cytarabine].
Topics: Antimetabolites, Antineoplastic; Child; Cytarabine; Cytidine Deaminase; Deoxycytidine Kinase; Gene Expression; Humans; Leukemia; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2008 |
[A retrospective analysis of clinical outcomes in 225 childhood with acute lymphoblastic leukemia].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Female; Humans; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Retrospective Studies; Survival Rate; Treatment Outcome | 2008 |
Changes in acetylcholinesterase (AchE) activity in lymphocytes and whole blood in acute lymphoblastic leukemia patients.
Topics: Acetylcholinesterase; Adolescent; Antineoplastic Agents; Child; Child, Preschool; Cytarabine; Female; Humans; Lymphocytes; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Young Adult | 2009 |
Effective treatment of advanced-stage childhood lymphoblastic lymphoma without prophylactic cranial irradiation: results of St Jude NHL13 study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; B-Lymphocytes; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Disease-Free Survival; Etoposide; Female; Follow-Up Studies; Humans; Injections, Spinal; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; T-Lymphocytes; Treatment Outcome; Vincristine | 2009 |
Additional chromosomal abnormalities and their prognostic significance in adult Philadelphia-positive acute lymphoblastic leukemia: with or without imatinib in chemotherapy.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Benzamides; Chromosome Aberrations; Cyclophosphamide; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Kaplan-Meier Estimate; Male; Mercaptopurine; Methotrexate; Middle Aged; Mitoxantrone; Piperazines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Pyrimidines; Salvage Therapy; Vincristine; Vindesine; Young Adult | 2009 |
Adults with acute lymphoblastic leukemia and translocation (1;19) abnormality have a favorable outcome with hyperfractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone alternating with methotrexate and high-dose cytarabine chemotherapy
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 19; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Humans; Methotrexate; Middle Aged; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Translocation, Genetic; Treatment Outcome; Vincristine | 2009 |
Pulmonary tuberculosis presenting as fever without source in a pediatric patient with acute lymphoblastic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Antitubercular Agents; Azithromycin; Child, Preschool; Combined Modality Therapy; Contact Tracing; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Drug Therapy, Combination; Ethambutol; Fever of Unknown Origin; Humans; Immunocompromised Host; Isoniazid; Lymphopenia; Male; Mycobacterium tuberculosis; Pneumonectomy; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary; Vincristine | 2009 |
[Prophylaxis and treatment of modified BFM-90 regimen for lymphoblastic lymphoma in children and adolescents accompanied with infection].
Topics: Adolescent; Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bacterial Infections; Cephalosporins; Child; Child, Preschool; Cross Infection; Cyclophosphamide; Cytarabine; Daunorubicin; Disease Progression; Female; Humans; Itraconazole; Male; Mercaptopurine; Methotrexate; Mouth Diseases; Mycoses; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Recurrence; Remission Induction; Respiratory Tract Infections; Vincristine | 2009 |
Weight patterns in children with higher risk ALL: A report from the Children's Oncology Group (COG) for CCG 1961.
Topics: Adolescent; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Body Mass Index; Child; Child, Preschool; Cranial Irradiation; Cytarabine; Daunorubicin; Ethnicity; Female; Gastrointestinal Diseases; Glucose Intolerance; Humans; Incidence; Male; Methotrexate; Obesity; Pancreatitis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Randomized Controlled Trials as Topic; Retrospective Studies; Risk; Vincristine; Weight Gain; Weight Loss; Young Adult | 2009 |
A comparative study of outcomes of idarubicin- and etoposide-intensified conditioning regimens for allogeneic peripheral blood stem cell transplantation in patients with high-risk acute leukemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Aspergillus; Busulfan; China; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Disease-Free Survival; Etoposide; Female; Graft Survival; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Hydroxyurea; Idarubicin; Immunosuppressive Agents; Leukemia; Leukemia, Myeloid, Acute; Male; Methylprednisolone; Mucositis; Pneumonia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Premedication; Retrospective Studies; Risk Factors; Semustine; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Whole-Body Irradiation | 2009 |
Clofarabine-based salvage chemotherapy for relapsed or refractory acute leukemia before allogeneic stem cell transplantation: results from a case series.
Topics: Acute Disease; Adenine Nucleotides; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cyclophosphamide; Cytarabine; Drug Resistance, Neoplasm; Female; Humans; Leukemia; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Myelomonocytic, Acute; Male; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Salvage Therapy; Stem Cell Transplantation; Transplantation, Homologous; Treatment Outcome | 2009 |
Methylene tetrahydrofolate reductase gene polymorphism in Egyptian children with acute lymphoblastic leukemia.
Topics: Alleles; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Egypt; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Male; Mercaptopurine; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasm Proteins; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Recurrence; Stomatitis; Vincristine | 2010 |
Working memory in survivors of childhood acute lymphocytic leukemia: functional neuroimaging analyses.
Topics: Adolescent; Age of Onset; Antineoplastic Agents; Brain; Brain Mapping; Child; Child, Preschool; Cytarabine; Female; Humans; Intelligence Tests; Magnetic Resonance Imaging; Male; Memory Disorders; Memory, Short-Term; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Survivors | 2010 |
Last exit clofarabine?
Topics: Acute Disease; Adenine Nucleotides; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cyclophosphamide; Cytarabine; Humans; Leukemia; Leukemia, Myeloid; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Salvage Therapy; Stem Cell Transplantation; Transplantation, Homologous; Treatment Outcome | 2009 |
Voreloxin, a first-in-class anticancer quinolone derivative, acts synergistically with cytarabine in vitro and induces bone marrow aplasia in vivo.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Blood Platelets; Bone Marrow Cells; Cell Proliferation; Cytarabine; Disease Models, Animal; Drug Synergism; Female; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Leukocytes; Mice; Naphthyridines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Thiazoles | 2010 |
[Inhibitive effect of artesunate on human lymphoblastic leukemia/lymphoma cells].
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Artemisinins; Artesunate; Blood-Brain Barrier; Cell Line, Tumor; Cytarabine; Drug Synergism; Humans; Jurkat Cells; Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2009 |
Hyperperfusion on magnetic resonance imaging in acute chemotherapy-related leukoencephalopathy.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Cytarabine; Diagnosis, Differential; Humans; Leukoencephalopathies; Magnetic Resonance Imaging; Male; Methotrexate; Polyethylene Glycols; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stroke; Vincristine | 2010 |
Prospective study of hemostatic alterations in children with acute lymphoblastic leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Antithrombins; Asparaginase; Case-Control Studies; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Fibrin Fibrinogen Degradation Products; Humans; Infant; Longitudinal Studies; Male; Mercaptopurine; Methotrexate; P-Selectin; Plasminogen Activator Inhibitor 1; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prospective Studies; Risk Factors; Thrombin; Thrombophilia; Venous Thromboembolism; Vincristine; von Willebrand Factor | 2010 |
Central nervous system complications during treatment of acute lymphoblastic leukemia in a single pediatric institution.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Central Nervous System; Central Nervous System Diseases; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Electroencephalography; Female; Humans; Infant; Leukemic Infiltration; Magnetic Resonance Imaging; Male; Mercaptopurine; Methotrexate; Peripheral Nervous System Diseases; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Retrospective Studies; Tomography, X-Ray Computed; Vincristine | 2010 |
Spinal cord compression by epidural involvement over 21 vertebral levels in acute lymphoblastic leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Epidural Neoplasms; Humans; Lumbar Vertebrae; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Sacrococcygeal Region; Spinal Cord Compression; Thoracic Vertebrae; Vincristine | 2011 |
Anthracycline dose intensification in adult acute lymphoblastic leukemia: lack of benefit in the context of the fractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone regimen.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Doxorubicin; Drug Administration Schedule; Humans; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Salvage Therapy; Treatment Outcome; Vincristine | 2010 |
Fludarabine, cytarabine, granulocyte colony-stimulating factor, and idarubicin (FLAG-IDA) for the treatment of children with poor-prognosis acute leukemia: the Hacettepe experience.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Survival Rate; Treatment Outcome; Vidarabine | 2010 |
Childhood acute lymphoblastic leukemia in Turkey: factors influencing treatment and outcome: a single center experience.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Follow-Up Studies; Humans; Infant; Male; Mercaptopurine; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Recurrence; Retrospective Studies; Risk Factors; Turkey; Vincristine | 2010 |
Outcome of treatment of adult acute lymphoblastic leukemia with hyperfractionated cyclophosphamide, doxorubicin, vincristine, dexamethasone/methotrexate, cytarabine: results from an Australian population.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Australia; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Female; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Survival Rate; Treatment Outcome; Vincristine; Young Adult | 2011 |
The effect of cerebral spinal fluid replacement on acute myelopathy induced by intrathecal therapy of leukemia.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System; Cerebrospinal Fluid; Cytarabine; Dexamethasone; Female; Fluid Therapy; Humans; Injections, Spinal; Methotrexate; Paraplegia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Spinal Cord Diseases; Treatment Outcome | 2011 |
Cellular elements of the subarachnoid space promote ALL survival during chemotherapy.
Topics: Antineoplastic Agents; Astrocytes; Cell Communication; Cell Line, Tumor; Cell Survival; Cells, Cultured; Choroid Plexus; Coculture Techniques; Cytarabine; Dexamethasone; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Meninges; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Subarachnoid Space; Time Factors | 2011 |
[A case of the association of acute lymphoblastic lymphoma with active tuberculosis in the child: a Malian case].
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Child, Preschool; Cytarabine; Humans; Injections, Intramuscular; Injections, Spinal; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction; Tuberculosis, Pulmonary; Vincristine | 2010 |
Numb chin syndrome in acute lymphoblastic leukemia.
Topics: Antineoplastic Agents; Child; Chin; Cytarabine; Female; Humans; Hypesthesia; Magnetic Resonance Imaging; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Skull | 2011 |
Homozygosity for the rs9939609T allele of the FTO gene may have protective effect on becoming overweight in survivors of childhood acute lymphoblastic leukaemia.
Topics: Adolescent; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Genetic Association Studies; Homozygote; Humans; Male; Methotrexate; Obesity; Odds Ratio; Overweight; Polymorphism, Single Nucleotide; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Proteins; Radiotherapy; Risk Factors; Survivors; Thioguanine; Vincristine; Young Adult | 2011 |
Important role of caspase-8 for chemosensitivity of ALL cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Caspase 8; Cell Line, Tumor; Cell Survival; Child; Cytarabine; Dexamethasone; Doxorubicin; Enzyme Activation; Humans; Jurkat Cells; Methotrexate; Mice; Mice, Inbred NOD; Mice, SCID; Precursor Cell Lymphoblastic Leukemia-Lymphoma; RNA Interference; Thioguanine; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2011 |
Methylated chrysin reduced cell proliferation, but antagonized cytotoxicity of other anticancer drugs in acute lymphoblastic leukemia.
Topics: Antineoplastic Agents; Apoptosis; Asparaginase; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclophosphamide; Cytarabine; Drug Interactions; Drug Screening Assays, Antitumor; E2F1 Transcription Factor; Flavonoids; Humans; Inhibitory Concentration 50; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Vincristine | 2012 |
The dual kinase inhibitor NVP-BEZ235 in combination with cytotoxic drugs exerts anti-proliferative activity towards acute lymphoblastic leukemia cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Cycle Checkpoints; Cell Growth Processes; Cell Line, Tumor; Cytarabine; Dexamethasone; Doxorubicin; Drug Resistance, Neoplasm; Drug Synergism; Humans; Imidazoles; Jurkat Cells; Leukemia, B-Cell; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Quinolines; Signal Transduction; TOR Serine-Threonine Kinases | 2012 |
Safety and efficacy of total body irradiation, cyclophosphamide, and cytarabine as a conditioning regimen for allogeneic hematopoietic stem cell transplantation in patients with acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Bone Marrow Transplantation; Chromosome Banding; Cord Blood Stem Cell Transplantation; Cyclophosphamide; Cytarabine; DNA, Neoplasm; Female; Hematopoietic Stem Cell Transplantation; HLA Antigens; Humans; Immunophenotyping; Japan; Male; Middle Aged; Myeloablative Agonists; Peripheral Blood Stem Cell Transplantation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Survival Rate; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Whole-Body Irradiation | 2012 |
Concurrent acute myeloid leukemia and T lymphoblastic lymphoma in a patient with rearranged PDGFRB genes.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Daunorubicin; Fatal Outcome; Graft vs Host Disease; Humans; Leukemia, Myeloid, Acute; Male; Neoplasms, Multiple Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptor, Platelet-Derived Growth Factor beta; Stem Cell Transplantation | 2012 |
FLAG-liposomal doxorubicin (Myocet) regimen for refractory or relapsed acute leukemia pediatric patients.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Doxorubicin; Drug Resistance, Neoplasm; Female; Granulocyte Colony-Stimulating Factor; Humans; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Male; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Salvage Therapy; Survival Rate; Vidarabine | 2012 |
Clofarabine-based chemotherapy for relapsed/refractory adult acute lymphoblastic leukemia and lymphoblastic lymphoma. The Spanish experience.
Topics: Adenine Nucleotides; Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cyclophosphamide; Cytarabine; Drug Evaluation; Etoposide; Female; Humans; Male; Middle Aged; Off-Label Use; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Salvage Therapy; Spain; Young Adult | 2012 |
Synergy of sequential administration of a deglycosylated ricin A chain-containing combined anti-CD19 and anti-CD22 immunotoxin (Combotox) and cytarabine in a murine model of advanced acute lymphoblastic leukemia.
Topics: Animals; Antibodies, Monoclonal; Antigens, CD19; Cell Line, Tumor; Cytarabine; Disease Models, Animal; Drug Combinations; Drug Synergism; Humans; Immunotoxins; Mice; Mice, Inbred NOD; Neoplasm Staging; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Ricin; Sialic Acid Binding Ig-like Lectin 2; Xenograft Model Antitumor Assays | 2012 |
[The efficacy of CAG regimen in treatment of adult patients with refractory or relapse acute lymphoblastic leukemia].
Topics: Aclarubicin; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Young Adult | 2012 |
Probable cytarabine-induced acral erythema: report of 2 pediatric cases.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Cytarabine; Etoposide; Female; Hand-Foot Syndrome; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis | 2013 |
Outcome of risk adapted therapy for relapsed/refractory acute lymphoblastic leukemia in children.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Drug Resistance, Neoplasm; Female; Hematopoietic Stem Cell Transplantation; Humans; Infant; Kaplan-Meier Estimate; Male; Multivariate Analysis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Recurrence; Remission Induction; Risk Factors; Treatment Outcome | 2013 |
Chemotherapy for initial induction failures in childhood acute lymphoblastic leukemia: a Children's Oncology Group Study (POG 8764).
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Female; Humans; Hydrocortisone; Infant; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Teniposide; Treatment Outcome; Young Adult | 2013 |
Wnt pathway contributes to the protection by bone marrow stromal cells of acute lymphoblastic leukemia cells and is a potential therapeutic target.
Topics: Animals; Apoptosis; beta Catenin; Cell Cycle; Cytarabine; Gene Expression Regulation, Leukemic; Heterocyclic Compounds, 3-Ring; Humans; Mesenchymal Stem Cells; Mice; Mice, SCID; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Wnt Signaling Pathway | 2013 |
Hypopyon as the first sign of relapse in acute lymphoblastic leukaemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Cyclophosphamide; Cytarabine; Doxorubicin; Eye Neoplasms; Fatal Outcome; Female; Humans; Mercaptopurine; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Vincristine | 2013 |
Symptomatic hypoglycemia in children receiving oral purine analogues for treatment of childhood acute lymphoblastic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Blood Glucose; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Hypoglycemia; Italy; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Purines; Retrospective Studies; Time Factors; Vincristine | 2002 |
Variant translocations of 11q23 in infant acute lymphoblastic leukemia (ALL): do outcomes differ from t(4;11)?
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 4; Cyclophosphamide; Cytarabine; Cytogenetic Analysis; Daunorubicin; DNA Primers; Female; Humans; Infant; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Translocation, Genetic; Vincristine | 2002 |
Increased factor VIII activity and dural sinus thrombosis.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Factor VIII; Humans; Magnetic Resonance Imaging; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Radiography; Risk Factors; Sagittal Sinus Thrombosis; Vincristine | 2002 |
CD7+ and CD56+ myeloid/natural killer cell precursor acute leukemia treated with idarubicin and cytosine arabinoside.
Topics: Acute Disease; Aged; Antigens, CD; Antigens, CD7; Antigens, Differentiation, Myelomonocytic; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; CD56 Antigen; Cytarabine; Daunorubicin; Diagnosis, Differential; Etoposide; Fatal Outcome; Humans; Idarubicin; Killer Cells, Natural; Leukemia, Myeloid; Leukemic Infiltration; Lymphoma, Non-Hodgkin; Male; Mercaptopurine; Mitoxantrone; Myeloid Cells; Neoplastic Stem Cells; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sarcoma, Myeloid; Sialic Acid Binding Ig-like Lectin 3 | 2002 |
Outcome of treatment in adults with Philadelphia chromosome-positive acute lymphoblastic leukemia--results of the prospective multicenter LALA-94 trial.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Follow-Up Studies; Fusion Proteins, bcr-abl; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Mitoxantrone; Neoplasm, Residual; Patient Selection; Ploidies; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Remission Induction; Reverse Transcriptase Polymerase Chain Reaction; Stem Cell Transplantation; Survival Analysis; Time Factors; Treatment Outcome | 2002 |
Improvement over time in outcome for children with acute lymphoblastic leukemia in second remission given hematopoietic stem cell transplantation from unrelated donors.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Disease-Free Survival; DNA, Neoplasm; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; HLA-A Antigens; HLA-B Antigens; HLA-DR Antigens; HLA-DRB1 Chains; Humans; Infant; Living Donors; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Registries; Remission Induction; Survival Rate; Time Factors; Transplantation, Homologous; Treatment Outcome; Vincristine | 2002 |
Differential mRNA expression of Ara-C-metabolizing enzymes explains Ara-C sensitivity in MLL gene-rearranged infant acute lymphoblastic leukemia.
Topics: Arabinofuranosylcytosine Triphosphate; Cell Survival; Child; Child, Preschool; Cytarabine; DCMP Deaminase; Deoxycytidine Kinase; DNA-Binding Proteins; Drug Resistance, Neoplasm; Equilibrative Nucleoside Transporter 1; Female; Gene Expression; Gene Rearrangement; Histone-Lysine N-Methyltransferase; Humans; Infant; Male; Myeloid-Lymphoid Leukemia Protein; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proto-Oncogenes; Pyrimidine Nucleotides; RNA, Messenger; Transcription Factors; Tumor Cells, Cultured | 2003 |
High-dose cytosine arabinoside-induced cutaneous reactions.
Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Cytarabine; Drug Eruptions; Female; Humans; Incidence; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies | 2002 |
Perfusion MRI and SPECT of brain after treatment for childhood acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Brain; Cerebrovascular Circulation; Cerebrovascular Disorders; Child; Child, Preschool; Cytarabine; Female; Humans; Iatrogenic Disease; Magnetic Resonance Imaging; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Technetium Tc 99m Exametazime; Tomography, Emission-Computed, Single-Photon; Vincristine | 2003 |
Favorable outcome with STI571 (imatinib mesylate) and allogeneic stem cell transplantation in a case of Ph+ chemorefractory acute lymphocytic leukaemia.
Topics: Adult; Amsacrine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Betamethasone; Biomarkers, Tumor; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Female; Fusion Proteins, bcr-abl; Graft vs Host Disease; Humans; Imatinib Mesylate; Immunosuppressive Agents; Mitoxantrone; Neoplasm, Residual; Peripheral Blood Stem Cell Transplantation; Piperazines; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyrimidines; Remission Induction; Reverse Transcriptase Polymerase Chain Reaction; Transplantation, Homologous; Vincristine | 2002 |
Dental abnormalities in children after chemotherapy treatment for acute lymphoid leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Cytarabine; Dental Enamel Hypoplasia; Dexamethasone; Doxorubicin; Etoposide; Female; Humans; Infant; Male; Mercaptopurine; Methotrexate; Odontogenesis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Teniposide; Tooth Abnormalities; Tooth Diseases; Tooth Eruption; Tooth Root; Vincristine | 2003 |
Posterior leukoencephalopathy following intrathecal chemotherapy with MRA-documented vasospasm.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Blindness; Brain Diseases; Cerebral Arteries; Cerebral Infarction; Cytarabine; Disease Progression; Female; Humans; Injections, Spinal; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Methotrexate; Middle Aged; Ocular Motility Disorders; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recovery of Function; Syndrome; Tachycardia; Vasospasm, Intracranial | 2003 |
Benign intracranial hypertension in association with acute lymphoblastic leukemia.
Topics: Acetazolamide; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Chlorthalidone; Cyclophosphamide; Cytarabine; Daunorubicin; Diagnosis, Differential; Headache; Humans; Intracranial Hypertension; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Sinus Thrombosis, Intracranial; Vincristine; Vomiting | 2003 |
[Ocular relapse of acute lymphoblastic leukemia].
Topics: Administration, Topical; Adrenal Cortex Hormones; Anterior Chamber; Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Cyclophosphamide; Cytarabine; Dexamethasone; Eye Neoplasms; Fatal Outcome; Humans; Methotrexate; Neoplasm Recurrence, Local; Paracentesis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radiotherapy, Adjuvant; Vincristine | 2002 |
Maternal and fetal outcomes in pregnancy complicated with acute leukemia: a single institutional experience with 10 pregnancies at 16 years.
Topics: Abortion, Spontaneous; Abortion, Therapeutic; Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Fatal Outcome; Female; Fetal Death; Follow-Up Studies; Gestational Age; Humans; Infant, Newborn; Leukemia, Myeloid; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pregnancy; Pregnancy Complications, Neoplastic; Pregnancy Outcome; Retrospective Studies; Turkey | 2003 |
Induction of long-term remission of a relapsed childhood B-acute lymphoblastic leukemia with rituximab chimeric anti-CD20 monoclonal antibody and autologous stem cell transplantation.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antigens, CD20; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Purging; Burkitt Lymphoma; Child; Combined Modality Therapy; Cytarabine; Dexamethasone; Etoposide; Humans; Immunotherapy; Leukemic Infiltration; Male; Meninges; Methotrexate; Peripheral Blood Stem Cell Transplantation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Recurrence; Remission Induction; Rituximab; Salvage Therapy; Testis; Topotecan; Transplantation, Autologous; Vindesine | 2003 |
Imatinib Mesylate (Gleevec) is a useful agent in the salvage treatment of adults with relapsed/refractory Philadelphia positive acute leukemias.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Benzamides; Cytarabine; Daunorubicin; Doxorubicin; Enzyme Inhibitors; Female; Fusion Proteins, bcr-abl; Hepatitis B; Humans; Imatinib Mesylate; Immunosuppressive Agents; Lamivudine; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Methotrexate; Middle Aged; Neoplasm Proteins; Peripheral Blood Stem Cell Transplantation; Piperazines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Pyrimidines; Remission Induction; Salvage Therapy; Vincristine | 2003 |
[The influence of age, gender and modifications of therapeutic protocols on physical development of children and adolescents after completion of therapy for acute lymphoblastic leukemia].
Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Body Mass Index; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Female; Growth; Humans; Longitudinal Studies; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radiotherapy, Adjuvant; Retrospective Studies; Risk Factors; Sex Factors; Thioguanine; Vincristine | 2003 |
Analysis of single nucleotide polymorphism C3435T of the multidrug resistance gene MDR1 in acute lymphoblastic leukemia.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Case-Control Studies; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Genes, MDR; Humans; Hydroxyurea; Male; Mercaptopurine; Methotrexate; Polymorphism, Single Nucleotide; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tumor Cells, Cultured; Vincristine | 2003 |
Disposition of liposomal daunorubicin during cotreatment with cytarabine in patients with leukaemia.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Liposomes; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2003 |
Cholelithiasis and choledocholithiasis after sequential cytarabine and asparaginase.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cholelithiasis; Cytarabine; Female; Humans; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Monocytic, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2003 |
cDNA microarray analysis of altered gene expression in Ara-C-treated leukemia cells.
Topics: Amino Acid Sequence; Apoptosis; Cell Differentiation; Cytarabine; DNA Mutational Analysis; Dose-Response Relationship, Drug; Gene Expression; Gene Expression Regulation; HL-60 Cells; Humans; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mitochondrial Proteins; Molecular Chaperones; Molecular Sequence Data; Oligonucleotide Array Sequence Analysis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Cells, Cultured | 2003 |
Multidrug resistance genes in infant acute lymphoblastic leukemia: Ara-C is not a substrate for the breast cancer resistance protein.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Survival; Cells, Cultured; Child; Child, Preschool; Cytarabine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fibroblasts; Gene Expression Regulation, Leukemic; Humans; Infant; Mice; Neoplasm Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Topotecan; Vault Ribonucleoprotein Particles | 2004 |
Protein expression of the glucocorticoid receptor in childhood acute lymphoblastic leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Case-Control Studies; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Leukemic; Humans; Male; Mercaptopurine; Methotrexate; Neoplasm Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Protein Isoforms; Receptors, Glucocorticoid; Treatment Outcome; Vincristine | 2003 |
Long-term survival following radiotherapy and cytarabine chemotherapy for sporadic primary central nervous system lymphoma.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Brain Neoplasms; Cause of Death; Combined Modality Therapy; Confidence Intervals; Cytarabine; Dose Fractionation, Radiation; Female; Follow-Up Studies; Humans; Injections, Intravenous; Injections, Spinal; Lymphoma; Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radiotherapy Dosage; Survival Analysis; Time Factors | 2003 |
Outcome of children with high-risk acute lymphoblastic leukemia (HR-ALL): Nordic results on an intensive regimen with restricted central nervous system irradiation.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Child; Child, Preschool; Cohort Studies; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Disease-Free Survival; Female; Humans; Infant; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Risk Factors; Stem Cell Transplantation; Transplantation, Homologous; Treatment Outcome | 2004 |
Relation between the duration of remission and hyperglycemia during induction chemotherapy for acute lymphocytic leukemia with a hyperfractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone/methotrexate-cytarabine regimen.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Female; Humans; Hyperglycemia; Infections; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Time Factors; Vincristine | 2004 |
Isolated central nervous system relapse in lymphoid blast crisis chronic myeloid leukemia and acute lymphoblastic leukemia in patients on imatinib therapy.
Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents; Benzamides; Blast Crisis; Bone Marrow; Central Nervous System Neoplasms; Cytarabine; Female; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Methotrexate; Middle Aged; Piperazines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyrimidines; Recurrence; Remission Induction | 2004 |
Stromal cell protection of B-lineage acute lymphoblastic leukemic cells during chemotherapy requires active Akt.
Topics: Animals; Antineoplastic Agents; Burkitt Lymphoma; Cell Survival; Coculture Techniques; Cytarabine; Etoposide; Humans; Mice; Phosphoprotein Phosphatases; Phosphorylation; Poly(ADP-ribose) Polymerases; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Stromal Cells | 2004 |
Treatment of isolated central nervous system relapse in high-risk lymphoid malignancy with allogeneic bone marrow transplantation and extended intrathecal therapy.
Topics: Antineoplastic Agents; Bone Marrow Transplantation; Central Nervous System Diseases; Chemotherapy, Adjuvant; Child; Child, Preschool; Cytarabine; Disease-Free Survival; Female; Humans; Hydrocortisone; Injections, Spinal; Lymphoma, Non-Hodgkin; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Transplantation Conditioning; Transplantation, Homologous | 2004 |
High-dose cytosine arabinoside and etoposide with total body irradiation as a preparatory regimen for allogeneic hematopoietic stem-cell transplantation in patients with acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Bone Marrow Transplantation; Child; Cytarabine; Etoposide; Female; Humans; Immunosuppressive Agents; Living Donors; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Siblings; Stem Cell Transplantation; Survival Analysis; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Whole-Body Irradiation | 2004 |
Prolonged fever of unknown origin and hemophagocytosis evolving into acute lymphoblastic leukemia.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Chromosome Aberrations; Cyclophosphamide; Cytarabine; Disease Progression; Doxorubicin; Fever of Unknown Origin; Histiocytosis, Non-Langerhans-Cell; Humans; Karyotyping; Male; Methotrexate; Middle Aged; Pancytopenia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Rituximab; Splenomegaly; Vincristine | 2004 |
[Significance of C-reaction protein for differential diagnosis of fever after chemotherapy on children with acute lymphoblastic leukemia].
Topics: Antimetabolites, Antineoplastic; C-Reactive Protein; Child; Child, Preschool; Cytarabine; Diagnosis, Differential; Female; Fever; Humans; Infant; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Teniposide | 2004 |
Unexpected response of hormone-refractory prostate cancer to treatment with an antileukemic chemotherapy regimen.
Topics: Adenocarcinoma; Anilides; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Drug Resistance, Neoplasm; Fatal Outcome; Goserelin; Humans; Immunocompromised Host; Male; Methotrexate; Middle Aged; Neoplasm Proteins; Neoplasms, Second Primary; Neutropenia; Nitriles; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostate-Specific Antigen; Prostatic Neoplasms; Recurrence; Sepsis; Tosyl Compounds; Vincristine | 2004 |
[Mobilization of peripheral blood stem cells with mitoxantrone and high-dose cytarabine chemotherapy and rhG-CSF in patients with hematopoietic malignancies].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Lymphoma; Male; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recombinant Proteins | 2004 |
The analysis of correlations between drug resistance and clinical/laboratory measures found in a group of children with all treated by ALL-BFM 90 protocol.
Topics: Adolescent; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Coloring Agents; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Female; Humans; In Vitro Techniques; Male; Mercaptopurine; Methotrexate; Multivariate Analysis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Predictive Value of Tests; Prednisone; Remission Induction; Sex Factors; Tetrazolium Salts; Thiazoles; Vincristine | 2004 |
[Primary study of relationship between serum level of VEGF and non-Hodgkin's lymphoma in children and adolescent patients].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Burkitt Lymphoma; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Vascular Endothelial Growth Factor A; Vincristine | 2004 |
[Efficacy of modified BFM-90 regimen on children and adolescents with T cell lymphoblastic lymphoma: a report of 20 cases].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Humans; Male; Mercaptopurine; Methotrexate; Neoplasm Recurrence, Local; Neoplasm Staging; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Stem Cell Transplantation; Survival Rate; Treatment Outcome; Vincristine | 2004 |
Combination of imatinib and cytarabine for the treatment of Philadelphia chromosome positive acute lymphoblastic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Benzamides; Cytarabine; Disease-Free Survival; Female; Humans; Imatinib Mesylate; Middle Aged; Piperazines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyrimidines; Remission Induction | 2005 |
[Immunologic monitoring in children with acute lymphoblastic leukemia during maintenance treatment with regard to co-existing infections].
Topics: Adolescent; Antigens; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Biomarkers; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Flow Cytometry; Humans; Immunoglobulins; Lymphocyte Activation; Lymphocytes; Male; Methotrexate; Monitoring, Immunologic; Poland; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Risk Factors; Statistics, Nonparametric; Thioguanine; Time Factors; Vincristine | 2004 |
Images in haematology. Combined central retinal artery and vein occlusions as the presenting signs of ocular relapse in acute lymphoblastic leukaemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemic Infiltration; Methotrexate; Middle Aged; Ophthalmoscopy; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Retinal Artery Occlusion; Retinal Vein Occlusion | 2005 |
[Treatment results in children with standard-risk acute lymphoblastic leukemia. Report of the Polish Pediatric Leukemia/Lymphoma Study Group].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow; Bone Neoplasms; Central Nervous System Neoplasms; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Infant; Infant, Newborn; Male; Mercaptopurine; Methotrexate; Poland; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Remission Induction; Retrospective Studies; Risk Factors; Secondary Prevention; Survival Analysis; Testicular Neoplasms; Time Factors; Treatment Outcome; Vincristine | 2004 |
Second induction in pediatric patients with recurrent acute lymphoid leukemia using DFCI-ALL protocols.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cytarabine; Doxorubicin; Female; Humans; Infant; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Recurrence; Retrospective Studies; Stem Cell Transplantation; Survival Analysis; Transplantation, Homologous; Treatment Outcome; Vincristine | 2005 |
[Treatment results with ALL-BFM-95 protocol in children with acute lymphoblastic leukemia in Hungary].
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Infant; Male; Mercaptopurine; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction; Risk Assessment; Survival Analysis; Treatment Outcome; Vincristine | 2005 |
In vitro sensitivity of leukemic cells to nucleoside derivatives in childhood acute leukemias: good activity in leukemic relapses.
Topics: Adolescent; Adult; Antineoplastic Agents; Cell Death; Child; Child, Preschool; Cladribine; Cytarabine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Humans; Infant; Infant, Newborn; Leukemia, Myeloid; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Tumor Cells, Cultured; Vidarabine | 2005 |
Cognitive changes in children treated for acute lymphoblastic leukemia with chemotherapy only according to the Pediatric Oncology Group 9605 protocol.
Topics: Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Brain; Child; Child, Preschool; Cognition Disorders; Cohort Studies; Cytarabine; Female; Hematinics; Humans; Hydrocortisone; Leucovorin; Male; Methotrexate; Neuropsychological Tests; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Wechsler Scales | 2005 |
Cellular drug sensitivity in MLL-rearranged childhood acute leukaemia is correlated to partner genes and cell lineage.
Topics: Acute Disease; Adolescent; Antineoplastic Agents; Cell Lineage; Child; Child, Preschool; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 9; Cytarabine; Cytotoxicity Tests, Immunologic; DNA-Binding Proteins; Doxorubicin; Drug Resistance, Neoplasm; Female; Fluorometry; Gene Rearrangement; Glucocorticoids; Histone-Lysine N-Methyltransferase; Humans; Infant; Infant, Newborn; Leukemia, Myeloid; Male; Myeloid-Lymphoid Leukemia Protein; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Proto-Oncogenes; Statistics, Nonparametric; Transcription Factors; Translocation, Genetic | 2005 |
[Disseminated cutaneous and visceral fusariosis in an aplastic patient: an unusual digestive entry].
Topics: Adult; Amsacrine; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Diet; Fusarium; Humans; Immunocompromised Host; Male; Mycoses; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyrimidines; Triazoles; Voriconazole | 2005 |
In vitro activity of imatinib in cells from patients with adult acute lymphoblastic leukemia.
Topics: Adult; Antineoplastic Agents; Asparaginase; Benzamides; Cell Survival; Cytarabine; Daunorubicin; Drug Interactions; Drug Screening Assays, Antitumor; Fluorometry; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Immunosuppressive Agents; Mercaptopurine; Philadelphia Chromosome; Piperazines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Pyrimidines; Tumor Cells, Cultured; Vincristine | 2005 |
Treatment of relapsed acute lymphoblastic leukemia after allogeneic bone marrow transplantation with chemotherapy followed by G-CSF-primed donor leukocyte infusion: a prospective study.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Humans; Idarubicin; Leukocyte Transfusion; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Recurrence; Tissue Donors; Transplantation, Homologous; Treatment Outcome | 2005 |
Ara-C fever and infections after high-dose ara-C treatment in pediatric lymphoid malignancies.
Topics: Adolescent; Antimetabolites, Antineoplastic; Biomarkers; C-Reactive Protein; Child; Child, Preschool; Cytarabine; Fever; Humans; Infant; Infections; Leukocyte Count; Lymphoma, Non-Hodgkin; Platelet Count; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies | 2005 |
[Therapeutic effects of chemotherapeutic regimens containing pirarubicin on the treatment of high-risk or refractory and relapsed acute leukemia in adults].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Doxorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Vincristine | 2005 |
FLAG-IDA in the treatment of refractory/relapsed acute leukaemias: single centre study.
Topics: Acute Disease; Adolescent; Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Vidarabine | 2005 |
FLAG-IDA in the treatment of refractory/relapsed adult acute lymphoblastic leukemia.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukocyte Count; Liver; Male; Middle Aged; Mucositis; Platelet Count; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Retrospective Studies; Salvage Therapy; Stem Cell Transplantation; Transplantation, Homologous; Treatment Outcome; Vidarabine | 2005 |
Alternative medicine remedies might stimulate viability of leukemic cells.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Case-Control Studies; Cat's Claw; Cell Line, Tumor; Cell Survival; Child; Child, Preschool; Croton; Cytarabine; Humans; Infant; Phytotherapy; Plant Extracts; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Statistics, Nonparametric; Tumor Cells, Cultured; Viscum album | 2006 |
[Treatment of refractory and relapsed acute lymphocytic leukemia in adults].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Male; Middle Aged; Mitoxantrone; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Retrospective Studies; Teniposide; Treatment Outcome; Vidarabine | 2005 |
Induction of impaired membrane phospholipid asymmetry in mature erythrocytes after chemotherapy.
Topics: Annexin A5; Antimetabolites, Antineoplastic; Bone Marrow; Cellular Senescence; Cytarabine; Erythrocyte Membrane; Erythropoiesis; Humans; Phospholipids; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2005 |
Feasibility of FLAG-IDA regimen in cases with relapsed/refractory acute leukemia cases.
Topics: Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chemical and Drug Induced Liver Injury; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Liver Diseases; Male; Mucositis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Stem Cell Transplantation; Transplantation, Homologous; Vidarabine | 2006 |
TLS/FUS-ERG fusion gene in acute lymphoblastic leukemia with t(16;21)(p11;q22) and monitoring of minimal residual disease.
Topics: Antineoplastic Combined Chemotherapy Protocols; Base Sequence; Chromosome Mapping; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 21; Cytarabine; Etoposide; Exons; Humans; Idarubicin; Infant; Male; Neoplasm, Residual; Oncogene Proteins, Fusion; Precursor Cell Lymphoblastic Leukemia-Lymphoma; RNA-Binding Protein FUS; Translocation, Genetic; Treatment Outcome | 2005 |
Alternative donor bone marrow transplant for children with Philadelphia chromosome ALL.
Topics: Adolescent; Adult; Bone Marrow Transplantation; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Disease-Free Survival; Donor Selection; Female; Glioblastoma; Graft vs Host Disease; Humans; Immunosuppressive Agents; Lymphocyte Depletion; Male; Neoplasms, Second Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Recurrence; Retrospective Studies; Transplantation Conditioning; Whole-Body Irradiation | 2006 |
MLL gene rearrangements have no direct impact on Ara-C sensitivity in infant acute lymphoblastic leukemia and childhood M4/M5 acute myeloid leukemia.
Topics: Cell Proliferation; Cytarabine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Gene Rearrangement; Histone-Lysine N-Methyltransferase; Humans; In Vitro Techniques; Leukemia, Monocytic, Acute; Leukemia, Myelomonocytic, Acute; Models, Biological; Myeloid-Lymphoid Leukemia Protein; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2006 |
Mitoxantrone and cytosine arabinoside (ARA-C) in adult acute leukemia: an interim report.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Clinical Trials as Topic; Cytarabine; Drug Administration Schedule; Humans; Infusions, Intravenous; Leukemia; Leukemia, Myeloid, Acute; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome | 1989 |
Amsacrine combined with etoposide and high-dose methylprednisolone as salvage therapy in acute lymphoblastic leukemia in children.
Topics: Adolescent; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Deoxycytidine; Dexamethasone; Drug Evaluation; Drug Synergism; Etoposide; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Infant; Leukemia-Lymphoma, Adult T-Cell; Male; Methylprednisolone; Neoplasm, Residual; Peripheral Blood Stem Cell Transplantation; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Recombinant Proteins; Remission Induction; Retrospective Studies; Salvage Therapy; Survival Analysis; Thiotepa; Topotecan; Treatment Outcome; Vidarabine; Vinblastine | 2005 |
p16 inactivation associated with aggressive clinical course and fatal outcome in TEL/AML1-positive acute lymphoblastic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Child; Chromosomes, Human, Pair 9; Combined Modality Therapy; Core Binding Factor Alpha 2 Subunit; Cyclin-Dependent Kinase Inhibitor p16; Cyclophosphamide; Cytarabine; Daunorubicin; Fatal Outcome; Gene Deletion; Genes, p16; Humans; Male; Mercaptopurine; Methotrexate; Neoplasm Proteins; Oncogene Proteins, Fusion; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Recurrence; Vincristine | 2005 |
Adolescents with acute lymphoblastic leukaemia: outcome on UK national paediatric (ALL97) and adult (UKALLXII/E2993) trials.
Topics: Adolescent; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Disease-Free Survival; Etoposide; Female; Humans; Male; Mercaptopurine; Methotrexate; Patient Selection; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Randomized Controlled Trials as Topic; Remission Induction; Research Design; Survival Analysis; Thioguanine; Transplantation, Autologous; Transplantation, Homologous; Treatment Outcome; Vincristine | 2007 |
Pulmonary arterial hypertension after childhood cancer therapy and bone marrow transplantation.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Bone Marrow Transplantation; Cyclophosphamide; Cytarabine; Female; Humans; Hyperplasia; Hypertension, Pulmonary; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Piperazines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyrimidines; Vasodilator Agents | 2006 |
Roles of protein C, protein S, and antithrombin III in acute leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Antithrombin III; Asparaginase; Cyclophosphamide; Cytarabine; Disseminated Intravascular Coagulation; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Myocardial Infarction; Peripheral Nervous System Diseases; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Predictive Value of Tests; Prednisone; Protein C; Protein S; Thrombosis; Vincristine | 2006 |
Unrelated cord blood transplantation after myeloablative conditioning in patients with acute leukemia aged between 50 and 55 years.
Topics: Acute Disease; Body Weight; Cord Blood Stem Cell Transplantation; Cytarabine; Female; Fetal Blood; Graft vs Host Disease; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Transplantation Conditioning | 2006 |
Outcome of treatment in adults with Philadelphia chromosome-positive and/or BCR-ABL--positive acute lymphoblastic leukemia-retrospective analysis of Polish Adult Leukemia Group (PALG).
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; Fusion Proteins, bcr-abl; Hematopoietic Stem Cell Transplantation; Humans; Karyotyping; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Mercaptopurine; Methotrexate; Middle Aged; Philadelphia Chromosome; Poland; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Retrospective Studies; Treatment Outcome | 2006 |
Compassionate use of intrathecal depot liposomal cytarabine as treatment of central nervous system involvement in acute leukemia: report of 6 cases.
Topics: Central Nervous System Neoplasms; Cytarabine; Delayed-Action Preparations; Empathy; Humans; Injections, Spinal; Liposomes; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2006 |
Cytosine arabinoside induces programmed endothelial cell death through the caspase-3 pathway.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Apoptosis; Caspase 3; Caspases; Cattle; Cell Survival; Cells, Cultured; Cognition Disorders; Colorimetry; Cytarabine; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Endothelium, Vascular; Humans; Hydrocortisone; Microscopy, Fluorescence; Microscopy, Polarization; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Statistics, Nonparametric | 2006 |
Central nervous system recurrence in adult patients with acute lymphoblastic leukemia: frequency and prognosis in 467 patients without cranial irradiation for prophylaxis.
Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Female; Humans; Hydrocortisone; Incidence; Lactate Dehydrogenases; Male; Methotrexate; Middle Aged; Multivariate Analysis; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Predictive Value of Tests; Prognosis; Retrospective Studies; Risk Factors; Survival Analysis | 2006 |
[Neurological complications during and after the treatment of acute lymphocytic leukemia].
Topics: Adolescent; Antineoplastic Agents; Asparaginase; Cerebrovascular Disorders; Child; Child, Preschool; Cytarabine; Dementia, Vascular; Epilepsy; Female; Follow-Up Studies; Humans; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radiotherapy; Thiamine Deficiency; Wernicke Encephalopathy | 2006 |
[Drug sensitivity of tumor cells in varieties of acute childhood leukemia].
Topics: Antigens, CD34; Antineoplastic Agents; Apoptosis; Asparagine; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Tumor Cells, Cultured; Vincristine | 2005 |
Ex vivo activity of thalidomide in childhood acute leukemia.
Topics: Angiogenesis Inhibitors; Cell Cycle; Child; Child, Preschool; Cytarabine; Female; Humans; Immunophenotyping; Infant; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Tetrazolium Salts; Thalidomide; Thiazoles | 2006 |
Efficacy of liposomal daunorubicin and cytarabine as reinduction chemotherapy in relapsed acute lymphoblastic leukaemia despite expression of multidrug resistance-related proteins.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Liposomes; Male; Middle Aged; Multidrug Resistance-Associated Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence | 2006 |
[Acute lymphoblastic leukemia in children with initial leucocytosis above 50,000/mm3: summary of treatment results of Polish Pediatric Leukemia/Lymphoma Study Group].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Infant; Leukocyte Count; Leukocytosis; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Retrospective Studies; Thioguanine; Treatment Outcome; Vincristine | 2006 |
Successful management of cerebral and pulmonary mucormycosis with liposomal amphotericin B in a 28-year-old woman with acute lymphoblastic leukemia.
Topics: Adult; Amphotericin B; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Brain Abscess; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Cytomegalovirus Infections; Daunorubicin; Dexamethasone; Etoposide; Fatal Outcome; Female; Humans; Immunocompromised Host; Liposomes; Lung Diseases, Fungal; Mercaptopurine; Mitoxantrone; Mucormycosis; Pneumonia, Viral; Postoperative Complications; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Transplantation, Homologous; Vincristine | 2006 |
A case of fusariosis in an immunocompromised patient successfully treated with liposomal amphotericin B.
Topics: Abscess; Amphotericin B; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Combined Modality Therapy; Cytarabine; Foot Dermatoses; Fusarium; Humans; Imatinib Mesylate; Immunocompromised Host; Liposomes; Male; Middle Aged; Muscular Diseases; Onychomycosis; Peripheral Blood Stem Cell Transplantation; Piperazines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyrimidines; Recurrence; Remission Induction; Reoperation; Rituximab; Teniposide; Triazoles; Voriconazole | 2006 |
[Twenty years of treating childhood acute lymphoblastic leukemia].
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Infant; Male; Mercaptopurine; Methotrexate; Multivariate Analysis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prednisone; Prognosis; Recurrence; Risk Factors; Survival Rate; Time Factors; Vincristine | 2006 |
Avascular necrosis--an antineoplastic-treatment-related toxicity: the experiences of two institutions.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Female; Humans; Incidence; Lymphoma, Non-Hodgkin; Male; Mercaptopurine; Osteonecrosis; Poland; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prednisone; Retrospective Studies; Vincristine | 2006 |
Cytosine arabinoside-metabolizing enzyme genes are underexpressed in children with MLL gene-rearranged acute lymphoblastic leukemia.
Topics: Antimetabolites, Antineoplastic; Case-Control Studies; Child; Child, Preschool; Cytarabine; Deoxycytidine Kinase; Equilibrative Nucleoside Transporter 1; Female; Gene Expression Regulation, Neoplastic; Gene Rearrangement; Humans; Infant; Male; Myeloid-Lymphoid Leukemia Protein; Neoplasm, Residual; Polymerase Chain Reaction; Precursor Cell Lymphoblastic Leukemia-Lymphoma; RNA, Messenger; Time Factors | 2006 |
Pharmacology of intracellular cytosine-arabinoside-5'-triphosphate in malignant cells of pediatric patients with initial or relapsed leukemia and in normal lymphocytes.
Topics: Adolescent; Arabinofuranosylcytosine Triphosphate; Cell Line; Cell Line, Tumor; Child; Child, Preschool; Chromatography, High Pressure Liquid; Cytarabine; Half-Life; Humans; Infant; Inhibitory Concentration 50; Lymphocytes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence | 2007 |
Myelopathy due to intrathecal chemotherapy: magnetic resonance imaging findings.
Topics: Adult; Antimetabolites, Antineoplastic; Cytarabine; Female; Humans; Injections, Spinal; Lymphoma, Non-Hodgkin; Magnetic Resonance Imaging; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Spinal Cord; Spinal Cord Diseases | 2007 |
[Superior sagittal sinus thrombosis during remission induction therapy for acute lymphoblastic leukemia].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Central Nervous System Neoplasms; Cyclophosphamide; Cytarabine; Doxorubicin; Facial Paralysis; Humans; Injections, Spinal; Male; Methotrexate; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction; Risk Factors; Sagittal Sinus Thrombosis; Vincristine | 2006 |
[Reults of treatment with protocols BFM 90 and BFM 95].
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Infant; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prednisone; Survival Rate; Vincristine | 2006 |
Transverse myelopathy following intrathecal administration of chemotherapy.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Fatal Outcome; Hodgkin Disease; Humans; Injections, Spinal; Leukemic Infiltration; Male; Methotrexate; Myelitis, Transverse; Peripheral Blood Stem Cell Transplantation; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2007 |
Absence of prognostic impact of CD13 and/or CD33 antigen expression in adult acute lymphoblastic leukemia. Results of the GIMEMA ALL 0496 trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Burkitt Lymphoma; CD13 Antigens; Cell Lineage; Cohort Studies; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Immunophenotyping; Leukemia-Lymphoma, Adult T-Cell; Male; Middle Aged; Multicenter Studies as Topic; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Radiotherapy, Adjuvant; Randomized Controlled Trials as Topic; Remission Induction; Sialic Acid Binding Ig-like Lectin 3 | 2007 |
Acute encephalopathy and cerebral vasospasm after multiagent chemotherapy including PEG-asparaginase and intrathecal cytarabine for the treatment of acute lymphoblastic leukemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Brain; Brain Diseases; Burkitt Lymphoma; Child; Cytarabine; Female; Follow-Up Studies; Humans; Injections, Spinal; Magnetic Resonance Angiography; Polyethylene Glycols; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sensitivity and Specificity; Treatment Outcome; Vasospasm, Intracranial | 2007 |
Expression of multidrug resistance (MDR) proteins and in vitro drug resistance in acute leukemias.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Cell Survival; Child; Child, Preschool; Coloring Agents; Cytarabine; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Infant; Inhibitory Concentration 50; Leukemia; Leukemia, Myeloid; Male; Methylphenazonium Methosulfate; Middle Aged; Neoplasm Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Staining and Labeling; Tetrazolium Salts; Thiazoles; Treatment Outcome; Tumor Cells, Cultured | 2007 |
Almost normal cognitive function in patients during therapy for childhood acute lymphoblastic leukemia without cranial irradiation according to ALL-BFM 95 and COALL 06-97 protocols: results of an Austrian-German multicenter longitudinal study and implicat
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cognition Disorders; Cranial Irradiation; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Humans; Injections, Spinal; Intelligence Tests; Longitudinal Studies; Male; Mercaptopurine; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prospective Studies; Psychomotor Performance; Risk Factors; Vincristine | 2007 |
Triple intrathecal therapy without cranial irradiation for central nervous system preventive therapy in childhood acute lymphoblastic leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Central Nervous System; Child; Child, Preschool; Cranial Irradiation; Cyclophosphamide; Cytarabine; Dexamethasone; Disease-Free Survival; Epirubicin; Female; Follow-Up Studies; Humans; Hydrocortisone; Infant; Injections, Spinal; Leukemic Infiltration; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Retrospective Studies; Risk; Survival Analysis; Vincristine | 2008 |
What is the best salvage therapy for treatment of isolated CNS relapse in elderly patients with imatinib-responsive Ph(+) ALL?
Topics: Anti-Inflammatory Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Bone Marrow; Cytarabine; Humans; Hydrocortisone; Imatinib Mesylate; Injections, Spinal; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Piperazines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyrimidines; Radiotherapy; Salvage Therapy | 2007 |
Biphenotypic acute leukaemia: a case series.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Female; Humans; Immunophenotyping; Leukemia; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome; Vincristine | 2007 |
A 'pre-induction course' with non-cross-reacting cytostatic drugs for rapid tumour load reduction improves outcome in adult acute lymphoblastic leukaemia.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Cytarabine; Drug Therapy, Combination; Etoposide; Female; Humans; Male; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome; Tumor Burden | 2007 |
Vincristine-induced acute neurotoxicity versus Guillain-Barré syndrome: a diagnostic dilemma.
Topics: Action Potentials; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Dexamethasone; Diagnosis, Differential; Erectile Dysfunction; Fatal Outcome; Guillain-Barre Syndrome; Humans; Hydrocortisone; Male; Methotrexate; Paraparesis; Paresthesia; Polyradiculoneuropathy; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Urination Disorders; Vincristine | 2007 |
Disseminated intravascular coagulation in acute leukemia at presentation and during induction therapy.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Disseminated Intravascular Coagulation; Female; Humans; Incidence; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Partial Thromboplastin Time; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prospective Studies; Remission Induction; Vincristine | 2007 |
A step forward in therapy for ALL in infants.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Infant; Infant, Newborn; Methotrexate; Multicenter Studies as Topic; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Randomized Controlled Trials as Topic | 2007 |
Re: Neurologic complications associated with intrathecal liposomal cytarabine given prophylactically in combination with high-dose methotrexate and cytarabine to patients with acute lymphocytic leukemia.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Encephalitis; Female; Humans; Injections, Spinal; Leukemic Infiltration; Liposomes; Male; Meninges; Meningitis; Methotrexate; Middle Aged; Papilledema; Polyradiculopathy; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Seizures | 2007 |
Intrathecal liposomal cytarabine for prevention of meningeal disease in patients with acute lymphocytic leukemia and high-grade lymphoma.
Topics: Adult; Aged; Cytarabine; Female; Humans; Injections, Spinal; Liposomes; Lymphoma, Non-Hodgkin; Male; Meningeal Neoplasms; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2007 |
Lipomembranous panniculitis in a patient with acute leukemia induced by chemotherapy.
Topics: Adipose Tissue; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Fat Necrosis; Female; Humans; Methotrexate; Panniculitis; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2008 |
Cytarabine induced noncardiogenic pulmonary edema in a case of acute lymphoblastic leukemia.
Topics: Adolescent; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Female; Glucocorticoids; Granulocyte Colony-Stimulating Factor; Humans; Methotrexate; Methylprednisolone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pulmonary Edema; Radiography; Vincristine | 2007 |
Relationship between in vitro chemosensitivity assessed with MTT assay and clinical outcomes in 103 patients with acute leukemia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Child; Child, Preschool; Coloring Agents; Cytarabine; Daunorubicin; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; Female; Humans; Infant; Leukemia, Biphenotypic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tetrazolium Salts; Thiazoles; Treatment Outcome | 2007 |
Two distinct molecular mechanisms underlying cytarabine resistance in human leukemic cells.
Topics: Antimetabolites, Antineoplastic; Cell Line, Tumor; Cytarabine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Equilibrative Nucleoside Transporter 1; Gene Expression Regulation, Neoplastic; Humans; Mutation; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2008 |
Treatment of high-risk acute lymphoblastic leukemia in children using the AL851 and ALHR88 protocols: a report from the Kyushu-Yamaguchi Children's Cancer Study Group in Japan.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Infant; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Remission Induction; Vincristine | 1996 |
Peripheral blood progenitor cell transplantation in lymphoma and leukemia using a single apheresis.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Colony-Forming Units Assay; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Hodgkin Disease; Humans; Length of Stay; Leukapheresis; Lymphoma; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Vincristine | 1993 |
[Pulmonary mucormycosis in leukemic patients. Apropos of 2 cases].
Topics: Adult; Aged; Amphotericin B; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Fatal Outcome; Granulocyte Colony-Stimulating Factor; Humans; Immunologic Factors; Itraconazole; Leukemia, Promyelocytic, Acute; Lung Diseases, Fungal; Male; Mercaptopurine; Methotrexate; Mitoxantrone; Mucormycosis; Neutropenia; Opportunistic Infections; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1994 |
CD34 expression is associated with major adverse prognostic factors in adult acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Aged; Amsacrine; Aneuploidy; Antibiotics, Antineoplastic; Antigens, CD; Antigens, CD34; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Biomarkers, Tumor; Bone Marrow Transplantation; Burkitt Lymphoma; Cell Differentiation; Chromosome Aberrations; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Disease-Free Survival; Female; Humans; Immunophenotyping; Life Tables; Logistic Models; Male; Middle Aged; Neoplastic Stem Cells; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Proportional Hazards Models; Remission Induction; Risk Factors; Salvage Therapy; Survival Analysis; Vincristine | 1995 |
Marked increase of peripheral blood myeloblasts following G-CSF therapy in a patient with acute lymphoblastic leukemia.
Topics: Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Child; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1995 |
Time-course of the recovery of cellular immune function after high-dose chemotherapy and peripheral blood progenitor cell transplantation for high-grade non-Hodgkin's lymphoma.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow Diseases; Busulfan; Carmustine; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Killer Cells, Lymphokine-Activated; Killer Cells, Natural; Leukapheresis; Lymphocyte Count; Lymphocyte Subsets; Lymphoma, B-Cell; Lymphoma, Non-Hodgkin; Male; Melphalan; Mesna; Middle Aged; Podophyllotoxin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Time Factors; Treatment Outcome; Vincristine | 1995 |
Allogeneic bone marrow transplantation for childhood acute lymphoblastic leukemia in second remission: factors predictive of survival, relapse and graft-versus-host disease.
Topics: Actuarial Analysis; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cause of Death; Child; Child, Preschool; Combined Modality Therapy; Cyclosporine; Cytarabine; Disease-Free Survival; Female; Follow-Up Studies; Graft vs Host Disease; Humans; Male; Melphalan; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Retrospective Studies; Survival Analysis; Treatment Outcome; Whole-Body Irradiation | 1995 |
High-dose chemotherapy with BEAC regimen and autologous bone marrow transplantation for intermediate grade and immunoblastic lymphoma: durable complete remissions, but a high rate of regimen-related toxicity.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmustine; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Disease-Free Survival; Etoposide; Female; Follow-Up Studies; Humans; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Retrospective Studies; Transplantation, Autologous; Treatment Outcome | 1995 |
The value of high-dose systemic chemotherapy and intrathecal therapy for central nervous system prophylaxis in different risk groups of adult acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cytarabine; Dexamethasone; Disease-Free Survival; Doxorubicin; Drug Administration Schedule; Humans; Infusions, Intravenous; Injections, Spinal; Life Tables; Mercaptopurine; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Retrospective Studies; Risk Factors; Survival Rate; Vincristine | 1995 |
Granulocyte colony-stimulating factor (CSF), macrophage-CSF, granulocyte-macrophage CSF, interleukin-3, and interleukin-6 levels in sera from children undergoing blood stem cell autografts.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Child; Cytarabine; Daunorubicin; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-3; Interleukin-6; Leukemia, Myeloid, Acute; Leukocyte Count; Lymphoma, Non-Hodgkin; Macrophage Colony-Stimulating Factor; Male; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stem Cell Transplantation; Time Factors; Transplantation, Autologous | 1993 |
[Peripheral blood stem cell transplantation in adult patients].
Topics: Adolescent; Adult; Blood Cell Count; Cell Separation; Chemotherapy, Adjuvant; Cytarabine; Etoposide; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Lymphoma; Middle Aged; Multiple Myeloma; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1993 |
Treatment of poor prognosis non-Hodgkin's lymphoma with intensive, inpatient combination chemotherapy of brief duration: long-term followup.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Leucovorin; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prednisone; Prognosis; Survival Analysis; Vincristine | 1993 |
Granulocyte colony-stimulating factor supportive treatment following intensive chemotherapy in acute lymphocytic leukemia in first remission.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Middle Aged; Mitoxantrone; Neutropenia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Vincristine | 1993 |
Polymorphic thiopurine methyltransferase in erythrocytes is indicative of activity in leukemic blasts from children with acute lymphoblastic leukemia.
Topics: Adolescent; Aneuploidy; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Marrow; Child; Child, Preschool; Cytarabine; Erythrocytes; Female; Humans; Lymphocytes; Male; Mercaptopurine; Methotrexate; Methyltransferases; Neoplasm Proteins; Neoplastic Stem Cells; Polymorphism, Genetic; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Remission Induction; Teniposide; Treatment Failure | 1995 |
Assessment of chemotherapy-induced emesis and evaluation of a reduced-dose intravenous ondansetron regimen in pediatric outpatients with leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Etoposide; Female; Humans; Infusions, Intravenous; Male; Nausea; Ondansetron; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Severity of Illness Index; Vomiting | 1995 |
Neutrophilic eccrine hidradenitis: report of two cases.
Topics: Child, Preschool; Cytarabine; Eccrine Glands; Female; Hidradenitis; Humans; Leukemia, Monocytic, Acute; Male; Necrosis; Neutrophils; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1995 |
Ifosfamide and etoposide in recurrent childhood acute lymphoblastic leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Etoposide; Female; Humans; Ifosfamide; Infant; Male; Mesna; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence | 1995 |
[Central nervous system relapses in acute lymphoblastic leukemia and different methods of prophylaxis].
Topics: Adolescent; Adult; Central Nervous System Neoplasms; Combined Modality Therapy; Cytarabine; Female; Humans; Male; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Retrospective Studies; Risk Factors; Survival Analysis | 1995 |
Acute lymphocytic leukaemia in the elderly: characteristics and outcome with the vincristine-adriamycin-dexamethasone (VAD) regimen.
Topics: Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dexamethasone; Humans; Middle Aged; Multivariate Analysis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Risk Factors; Survival Analysis; Treatment Outcome; Vincristine | 1994 |
[Hemostasis in patients with acute leukemia treated with high doses of cytosine-arabinoside: the effect of chemotherapy and infectious complications on hemostasis].
Topics: Acute Disease; Adolescent; Adult; Cytarabine; Female; Hemostasis; Humans; Leukemia, Myeloid; Male; Middle Aged; Opportunistic Infections; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1994 |
Small noncleaved cell lymphoma and leukemia in adults. A retrospective study of 65 adults treated with the LMB pediatric protocols.
Topics: Adolescent; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Cyclophosphamide; Cytarabine; Female; Humans; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Neoplasm Staging; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pregnancy; Prognosis; Retrospective Studies; Survival Rate; Treatment Outcome | 1995 |
Aggressive chemotherapy for acute leukemia relapsed after transplantation.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Female; Humans; Idarubicin; Italy; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Male; Middle Aged; Neoplasm, Residual; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Retrospective Studies; Salvage Therapy; Survival Analysis; Treatment Outcome; Tretinoin; Vincristine | 1994 |
Low frequency of activity of P-glycoprotein (P-170) in acute lymphoblastic leukemia compared to acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Marrow; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Resistance, Multiple; Female; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Neoplasm Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Remission Induction; Rhodamine 123; Rhodamines; Survival Analysis | 1995 |
Childhood acute lymphoblastic leukemia (ALL): sister chromatid exchange (SCE) frequency and lymphocyte subpopulations during therapy.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Chromosomes, Human; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Immunophenotyping; Infant; Lymphocyte Count; Lymphocyte Subsets; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Sister Chromatid Exchange; Time Factors; Vincristine | 1995 |
Cytosine arabinoside and mitoxantrone treatment of relapsed or refractory childhood leukemia: initial response and relationship to multidrug resistance gene 1.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Carrier Proteins; Child; Child, Preschool; Cytarabine; Drug Evaluation; Drug Resistance; Female; Gene Expression; Humans; Infant; Leukemia; Leukemia, Myeloid, Acute; Male; Membrane Glycoproteins; Mitoxantrone; Molecular Sequence Data; Polymerase Chain Reaction; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction | 1994 |
Impact of reinduction regimens for relapsed and refractory acute lymphoblastic leukemia in adults.
Topics: Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Aspartate-Ammonia Ligase; Clinical Trials as Topic; Cytarabine; Dose-Response Relationship, Drug; Humans; Idarubicin; Incidence; Methotrexate; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Salvage Therapy | 1994 |
Mitoxantrone and standard dose cytosine arabinoside therapy in refractory or relapsed acute leukemia.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Time Factors | 1994 |
Treatment of primary refractory and relapsed acute lymphoblastic leukaemia in children and adults: the GIMEMA/AIEOP experience. Gruppo Italiano Malattie Ematologiche Maligne dell'Adulto. Associazione Italiana Ematologìa ed Ocologia Pediatrica.
Topics: Adolescent; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Female; Follow-Up Studies; Humans; Idarubicin; Infant; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Prospective Studies; Recurrence | 1994 |
Allogeneic bone marrow transplantation for acute lymphoblastic leukaemia: risk factors and clinical outcome.
Topics: Adolescent; Adult; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Female; Humans; Infant; Infant, Newborn; Leukocyte Count; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Recurrence; Risk Factors; Transplantation, Homologous; Treatment Outcome; Whole-Body Irradiation | 1994 |
Bone marrow purging in acute leukemia with alkyl-lysophospholipids: a new family of anticancer drugs.
Topics: Antineoplastic Agents; Bone Marrow Purging; Bone Marrow Transplantation; Cyclophosphamide; Cytarabine; Etoposide; Humans; Leukemia, Myeloid, Acute; Leukocyte Count; Phospholipid Ethers; Platelet Count; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Survival Analysis; Whole-Body Irradiation | 1994 |
[The effect of polychemotherapy on hemopoiesis in acute lymphoblastic leukemia in children].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Female; Hematopoiesis; Humans; Infant; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction; Time Factors; Vincristine | 1993 |
A dental complication involving Pseudomonas during chemotherapy for acute lymphoblastic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Cytarabine; Dental Care for Chronically Ill; Female; Humans; Immunocompromised Host; Methotrexate; Periapical Abscess; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Pseudomonas aeruginosa; Pseudomonas Infections; Remission Induction; Vincristine | 1994 |
Poor outcome of intensive chemotherapy for adult acute lymphoblastic leukemia: a possible dose effect.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Leucovorin; Male; Mercaptopurine; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Recurrence; Remission Induction; Retrospective Studies; Survival Rate; Teniposide; Vincristine | 1994 |
Histologic changes in dental morphology induced by high dose chemotherapy and total body irradiation.
Topics: Abnormalities, Radiation-Induced; Amelogenesis; Antineoplastic Agents; Asparaginase; Bone Marrow Transplantation; Child, Preschool; Cyclophosphamide; Cytarabine; Dental Arch; Dental Enamel Hypoplasia; Dentinogenesis; Doxorubicin; Female; Humans; Immunosuppressive Agents; Maxillofacial Development; Mercaptopurine; Methotrexate; Odontogenesis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Tooth Eruption; Tooth Root; Vincristine; Whole-Body Irradiation | 1994 |
The multiface morphology of acute leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cell Differentiation; Cytarabine; Daunorubicin; Fatal Outcome; Female; Hematopoietic Stem Cells; Humans; Immunophenotyping; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction | 1993 |
Plasma and leukemic cell pharmacokinetics of high-dose N4-behenoyl-1-beta-D-arabinofuranosylcytosine in acute leukemia patients.
Topics: Antineoplastic Agents; Arabinofuranosyluracil; Chromatography, High Pressure Liquid; Cytarabine; Half-Life; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1994 |
[Treatment of acute lymphoblastic leukemia in adults by the modified protocol of L-10M (Sloan-Kettering): long-term outcome].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Doxorubicin; Female; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Remission Induction; Treatment Outcome | 1994 |
Successful treatment of acute lymphoblastic leukemia in a child with cystic fibrosis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child, Preschool; Cystic Fibrosis; Cytarabine; Daunorubicin; Female; Humans; Mercaptopurine; Methotrexate; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Teniposide; Vincristine | 1994 |
Myelopathy after intrathecal chemotherapy. A case report with unique magnetic resonance imaging changes.
Topics: Adolescent; Antineoplastic Agents; Contrast Media; Cytarabine; Drug Combinations; Female; Gadolinium DTPA; Humans; Injections, Spinal; Magnetic Resonance Imaging; Meglumine; Methotrexate; Organometallic Compounds; Paraplegia; Pentetic Acid; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Spinal Cord Diseases | 1994 |
Effects of macrophage colony-stimulating factor (M-CSF) on the mobilization of peripheral blood stem cells.
Topics: Acute Disease; Adolescent; Adult; Blood Cells; Cell Movement; Cells, Cultured; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Female; Hematopoietic Stem Cells; Humans; Leukapheresis; Leukemia, Myeloid; Macrophage Colony-Stimulating Factor; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1994 |
Regulation of thymidine kinase and thymidylate synthase in intact human lymphoblast CCRF-CEM cells.
Topics: Aphidicolin; Carbon Radioisotopes; Cell Cycle; Cytarabine; Deoxycytidine; Deoxyuridine; DNA Replication; DNA, Neoplasm; Hydroxyurea; Kinetics; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Thymidine Kinase; Thymidylate Synthase; Time Factors; Tritium; Tumor Cells, Cultured | 1993 |
Treatment of relapsed or refractory acute leukemia in childhood with bisantrene combined with high dose aracytine.
Topics: Adolescent; Adult; Anthracenes; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Follow-Up Studies; Heart Diseases; Hematologic Diseases; Humans; Infant; Kidney Diseases; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction | 1994 |
Minimal residual disease status in pre-B acute lymphoblastic leukemia patients after chemotherapy and bone marrow transplantation: assessment of the anti-leukemic effects of chemotherapy and BMT.
Topics: Antineoplastic Combined Chemotherapy Protocols; Base Sequence; Bone Marrow; Bone Marrow Transplantation; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Genes, Immunoglobulin; Humans; Immunoglobulin Heavy Chains; Melphalan; Molecular Sequence Data; Polymerase Chain Reaction; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Prospective Studies; Transplantation, Autologous; Transplantation, Homologous; Whole-Body Irradiation | 1993 |
Prediction of chemotherapy response in human leukemia using in vitro chemosensitivity test.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Coloring Agents; Cytarabine; Daunorubicin; Drug Screening Assays, Antitumor; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Tetrazolium Salts; Thiazoles | 1993 |
Changes in the oral microflora during cytotoxic chemotherapy in children being treated for acute leukemia.
Topics: Adolescent; Analysis of Variance; Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bacterial Infections; Candida albicans; Candidiasis, Oral; Chi-Square Distribution; Child; Child, Preschool; Chlorhexidine; Colony Count, Microbial; Cytarabine; Daunorubicin; Etoposide; Female; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Infant; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Mouth; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Streptococcus mutans; Thioguanine; Trimethoprim, Sulfamethoxazole Drug Combination; Vincristine | 1993 |
[Treatment and prognosis after late relapse in childhood acute lymphoblastic leukemia].
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Drug Administration Schedule; Female; Humans; Infant; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Recurrence; Time Factors; Vincristine | 1993 |
[Acute lymphoblastic leukemia in infants--results of treatment according to infant leukemia protocol--POG 8493].
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cortisone; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Drug Administration Schedule; Female; Humans; Infant; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Survival Rate; Vincristine | 1993 |
ABMT for early isolated extramedullary relapse of childhood ALL.
Topics: Adolescent; Bone Marrow Purging; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Female; Humans; Infant; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Transplantation, Autologous; Whole-Body Irradiation | 1993 |
Neurotoxicity associated with fludarabine and cytosine arabinoside chemotherapy for acute leukemia and myelodysplasia.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Cytarabine; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Myelodysplastic Syndromes; Nervous System Diseases; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Vidarabine | 1993 |
Intensive alternating drug pairs for treatment of high-risk childhood acute lymphoblastic leukemia. A Pediatric Oncology Group pilot study.
Topics: Administration, Oral; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Humans; Hydrocortisone; Infant; Injections, Intramuscular; Injections, Intravenous; Injections, Spinal; Leukemia-Lymphoma, Adult T-Cell; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Teniposide; Treatment Failure | 1993 |
[Treatment of adult acute lymphoblastic leukemia with DCVP-l-asp protocol].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Male; Mercaptopurine; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Survival Rate; Vincristine | 1993 |
Neutrophilic eccrine hidradenitis.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Facial Dermatoses; Female; Hidradenitis; Humans; Leukemia, Myeloid; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1993 |
Clinical trials referral resource. Acute lymphocytic leukemia.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Clinical Trials as Topic; Cytarabine; Humans; Lymphoma, Non-Hodgkin; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1993 |
Child cerebrospinal fluid analysis by capillary electrophoresis and laser-induced fluorescence detection.
Topics: Adolescent; Amines; Amino Acids; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Electrophoresis, Capillary; Female; Humans; Lasers; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Spectrometry, Fluorescence | 1995 |
Hemorrhagic cystitis associated with BKV in patients with refractory acute lymphoblastic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; BK Virus; Cyclophosphamide; Cystitis; Cytarabine; Hemorrhage; Humans; Immunocompromised Host; Mesna; Papillomavirus Infections; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Tumor Virus Infections; Vincristine | 1996 |
True histiocytic lymphoma following therapy for lymphoblastic neoplasms.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Neoplasms; Child; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Etoposide; Fatal Outcome; Humans; Ifosfamide; Lymphoma, Large B-Cell, Diffuse; Male; Mediastinal Neoplasms; Mercaptopurine; Methotrexate; Methylprednisolone; Neoplasms, Second Primary; Neoplastic Stem Cells; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prednisone; Remission Induction; Scapula; Spinal Neoplasms; Vincristine | 1996 |
A T cell lymphoblastic lymphoma patient with two malignant cell populations carrying different 9p deletions including the p16INK4 and p15INK4B genes: Clinical response to interferon-alpha therapy in one of the subclones.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Carrier Proteins; Cell Cycle Proteins; Chromosome Deletion; Chromosomes, Human, Pair 9; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p16; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Fatal Outcome; Gene Deletion; Humans; Immunologic Factors; Interferon-alpha; Male; Neoplasm Proteins; Neoplastic Stem Cells; Polymerase Chain Reaction; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; RNA, Messenger; RNA, Neoplasm; Salvage Therapy; Tumor Suppressor Proteins; Vincristine | 1996 |
CD7 positive acute lymphoblastic leukemia successfully treated with high dose cytosine arabinoside and mitoxantrone: a case report.
Topics: Antigens, CD7; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction | 1996 |
Intrathecal leucovorin after intrathecal methotrexate overdose.
Topics: Catheterization, Central Venous; Child; Cytarabine; Drug Overdose; Humans; Hydrocortisone; Injections, Spinal; Leucovorin; Male; Medication Errors; Methotrexate; Neutropenia; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1996 |
Effectiveness of intensified rotational combination chemotherapy for late hematologic relapse of childhood acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Disease-Free Survival; Drug Administration Schedule; Female; Growth Disorders; Humans; Hydrocortisone; Leukemic Infiltration; Life Tables; Male; Meninges; Methotrexate; Neoplasms, Second Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Proportional Hazards Models; Prospective Studies; Remission Induction; Salvage Therapy; Survival Analysis; Survival Rate; Teniposide; Testis; Time Factors; Treatment Outcome; Vincristine | 1996 |
[Paraplegia following intrathecal chemotherapy].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cisplatin; Cytarabine; Etoposide; Humans; Injections, Spinal; Male; Paraplegia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone | 1996 |
The combination of melphalan, cyclophosphamide and cytosine arabinoside as a conditioning regimen for autologous bone marrow transplantation for acute leukemia.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Purging; Bone Marrow Transplantation; Cyclophosphamide; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Male; Melphalan; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1996 |
Lenńox-Gastaut syndrome associated with leukoencephalopathy.
Topics: Adolescent; Anticonvulsants; Antineoplastic Combined Chemotherapy Protocols; Brain Damage, Chronic; Calcinosis; Cranial Irradiation; Cytarabine; Dementia; Doxorubicin; Electroencephalography; Epilepsy, Absence; Epilepsy, Generalized; Humans; Injections, Spinal; Male; Mercaptopurine; Methotrexate; Movement Disorders; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Radiation Injuries; Syndrome; Vincristine | 1996 |
Intensive oral methotrexate protects against lymphoid marrow relapse in childhood B-precursor acute lymphoblastic leukemia.
Topics: Administration, Oral; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cytarabine; Drug Administration Schedule; Etoposide; Female; Humans; Infant; Male; Mercaptopurine; Methotrexate; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence | 1996 |
Acute lymphoblastic leukemia in Ehlers-Danlos syndrome.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child, Preschool; Cytarabine; Disease-Free Survival; Doxorubicin; Ehlers-Danlos Syndrome; Female; Humans; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Vincristine | 1996 |
[Gonadal function after chemotherapy for acute lymphoblastic leukemia].
Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Child; Cyclophosphamide; Cytarabine; Female; Gonads; Humans; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1996 |
[Obesity as the first manifestation of central nervous system involvement in acute lymphoblastic leukemia].
Topics: Antineoplastic Agents; Body Mass Index; Child; Combined Modality Therapy; Cytarabine; Drug Therapy, Combination; Female; Humans; Hydrocortisone; Methotrexate; Obesity; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radiation Dosage; Recurrence | 1996 |
High antileukemic activity of sequential high dose cytosine arabinoside and mitoxantrone in patients with refractory acute leukemias. Results of a clinical phase II study.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction | 1997 |
Phase I clinical and laboratory evaluation of topotecan and cytarabine in patients with acute leukemia.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blast Crisis; Camptothecin; Cytarabine; Drug Administration Schedule; Female; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Topotecan | 1997 |
In vitro drug sensitivity testing can predict induction failure and early relapse of childhood acute lymphoblastic leukemia.
Topics: Aclarubicin; Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bleomycin; Bone Marrow; Cell Survival; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Disease-Free Survival; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Etoposide; Follow-Up Studies; Humans; Infant; Infant, Newborn; Life Tables; Melphalan; Methotrexate; Mitomycin; Mitoxantrone; Neoplastic Stem Cells; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Recurrence; Remission Induction; Tumor Cells, Cultured; Vincristine | 1997 |
Bronchiolitis obliterans organizing pneumonia in three children with acute leukaemias treated with cytosine arabinoside and anthracyclines.
Topics: Anthracyclines; Antimetabolites, Antineoplastic; Bronchial Diseases; Child; Cryptogenic Organizing Pneumonia; Cytarabine; Female; Humans; Leukemia, Promyelocytic, Acute; Lung; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1997 |
Toxicity associated with high-dose cytosine arabinoside and total body irradiation as conditioning for allogeneic bone marrow transplantation.
Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Female; Humans; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Transplantation Conditioning; Transplantation, Homologous; Whole-Body Irradiation | 1997 |
Nutritional state alterations in children with acute lymphoblastic leukemia during induction and consolidation of chemotherapy.
Topics: Adolescent; Anthropometry; Antineoplastic Combined Chemotherapy Protocols; Arm; Asparaginase; Body Constitution; Child; Child, Preschool; Cohort Studies; Cytarabine; Drug Administration Schedule; Energy Metabolism; Epirubicin; Female; Gastrointestinal Diseases; Hospitals, General; Hospitals, Pediatric; Humans; Infant; Male; Mercaptopurine; Methotrexate; Nutrition Disorders; Nutritional Status; Obesity; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Risk; Skinfold Thickness; Vincristine | 1997 |
Deoxycytidine in human plasma: potential for protecting leukemic cells during chemotherapy.
Topics: Adult; Cladribine; Cytarabine; Deoxycytidine; Deoxycytosine Nucleotides; Humans; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Vidarabine | 1997 |
Salvage therapy for relapsed or refractory childhood acute lymphocytic leukemia by alternative administration a lymphoid- and myeloid-directed chemotherapeutic regimen consisting of dual modulation of ara-C, hydroxyurea, and etoposide.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Child; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dexamethasone; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Fever; Gastrointestinal Diseases; Humans; Hydrocortisone; Hydroxyurea; Leucovorin; Male; Methotrexate; Mitoxantrone; Pilot Projects; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Salvage Therapy; Treatment Outcome | 1997 |
"Reaction to cytarabine (Ara-C) treatment in patients with concurrent Staphylococcus aureus infection: a coalition between Ara-C and superantigens?".
Topics: Antimetabolites, Antineoplastic; Child, Preschool; Cytarabine; Female; Humans; Leukemia, Myelomonocytic, Acute; Male; Mucocutaneous Lymph Node Syndrome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Shock, Septic; Staphylococcal Infections; Staphylococcus aureus; Superantigens | 1998 |
High dose cytosine arabinoside is a major risk factor for the development of hepatosplenic candidiasis in patients with leukemia.
Topics: Adult; Antibiotic Prophylaxis; Antimetabolites, Antineoplastic; Candidiasis; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neutropenia; Opportunistic Infections; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Risk Factors | 1997 |
Cranial irradiation and permeability of blood-brain barrier to cytosine arabinoside in children with acute leukemia.
Topics: Adolescent; Antimetabolites, Antineoplastic; Blood-Brain Barrier; Brain Neoplasms; Child; Child, Preschool; Cranial Irradiation; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1998 |
Leukemic cells with 11q23 translocations express granulocyte colony-stimulating factor (G-CSF) receptor and their proliferation is stimulated with G-CSF.
Topics: Antineoplastic Combined Chemotherapy Protocols; B-Lymphocytes; Blast Crisis; Cell Division; Cell Line; Chromosome Mapping; Chromosomes, Human, Pair 11; Cytarabine; DNA Replication; Etoposide; Granulocyte Colony-Stimulating Factor; Granulocytes; Humans; Immunophenotyping; Infant; Male; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, Granulocyte Colony-Stimulating Factor; Tumor Cells, Cultured | 1998 |
Assessment of the emetogenic potential of intrathecal chemotherapy and response to prophylactic treatment with ondansetron.
Topics: Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Female; Humans; Hydrocortisone; Injections, Spinal; Male; Methotrexate; Nausea; Ondansetron; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome | 1998 |
Acute basal ganglia necrosis associated with cytarabine therapy.
Topics: Acute Disease; Antimetabolites, Antineoplastic; Basal Ganglia; Child, Preschool; Cytarabine; Humans; Male; Necrosis; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1998 |
High-dose therapy in acute leukemia.
Topics: Acute Disease; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Transplantation Conditioning; Transplantation, Autologous; Transplantation, Homologous | 1997 |
[Retrospective analysis of elderly patients > or = 60 years of age with acute leukemia].
Topics: Aclarubicin; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Daunorubicin; DNA; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Retrospective Studies; Vincristine | 1998 |
Acute lymphoblastic leukemia: dental health of children in maintenance therapy.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Case-Control Studies; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Dental Care for Chronically Ill; Dental Caries; DMF Index; Female; Humans; Male; Mercaptopurine; Methotrexate; Oral Hygiene; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Vincristine | 1998 |
Early intensification of intrathecal chemotherapy virtually eliminates central nervous system relapse in children with acute lymphoblastic leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System; Child; Child, Preschool; Cytarabine; Humans; Hydrocortisone; Injections, Spinal; Leukemic Infiltration; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence | 1998 |
Cellular immune responses in acute leukaemia patients with severe chemotherapy-induced leucopenia; characterization of the cytokine repertoire of clonogenic T cells.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Clone Cells; Cytarabine; Cytokines; Daunorubicin; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-10; Interleukin-2; Leukemia, Myeloid; Leukopenia; Lymphopenia; Male; Middle Aged; Phytohemagglutinins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stimulation, Chemical | 1998 |
Relation between age, immunophenotype and in vitro drug resistance in 395 children with acute lymphoblastic leukemia--implications for treatment of infants.
Topics: Adolescent; Adult; Age Distribution; Age Factors; Antineoplastic Agents; Child; Child, Preschool; Cytarabine; Daunorubicin; Dexamethasone; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Immunophenotyping; Infant; Infant, Newborn; Lymphoma, B-Cell; Lymphoma, T-Cell; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone | 1998 |
Influence of increased body mass index on drug toxicity in patients with acute promyelocytic leukemia.
Topics: Adult; Aged; Amsacrine; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Body Mass Index; Cytarabine; Daunorubicin; Female; Heart; Heart Failure; Humans; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Obesity; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Tretinoin | 1998 |
Childhood acute lymphoblastic leukaemia: outcomes of 54 consecutive patients treated in Auckland 1985-1991.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cranial Irradiation; Cyclophosphamide; Cytarabine; Daunorubicin; Humans; Infant; Mercaptopurine; Methotrexate; New Zealand; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Proportional Hazards Models; Prospective Studies; Radiotherapy, Adjuvant; Survival Analysis; Treatment Outcome; Vincristine | 1998 |
FLAG-idarubicin and allogeneic stem cell transplantation for Ph-positive ALL beyond first remission.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Combined Modality Therapy; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Male; Philadelphia Chromosome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Transplantation, Homologous; Treatment Outcome; Vidarabine | 1998 |
Intraventricular concentration times time (C x T) methotrexate and cytarabine for patients with recurrent meningeal leukemia and lymphoma.
Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Child; Child, Preschool; Cytarabine; Female; Humans; Injections, Intraventricular; Male; Meningeal Neoplasms; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Treatment Outcome | 1999 |
Early detection by ultrasound scan of severe post-chemotherapy gut complications in patients with acute leukemia.
Topics: Acute Disease; Adult; Anti-Infective Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dilatation, Pathologic; Enterocolitis; Etoposide; Female; Gallbladder Diseases; Gastrointestinal Diseases; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Intubation, Gastrointestinal; Leukemia; Leukemia, Myelomonocytic, Acute; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Neutropenia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome; Ultrasonography | 1999 |
Neurodevelopmental outcome of infants with acute lymphoblastic leukemia: a Children's Cancer Group report.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Brain Damage, Chronic; Cognition Disorders; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Daunorubicin; Developmental Disabilities; Female; Follow-Up Studies; Humans; Infant; Injections, Spinal; Leucovorin; Leukemic Infiltration; Male; Mercaptopurine; Methotrexate; Movement Disorders; Neuropsychological Tests; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Psychomotor Performance; Remission Induction; Risk; Socioeconomic Factors; Survivors; Vincristine | 1999 |
Effects of interleukin 3, interleukin 7, and B-cell growth factor on proliferation and drug resistance in vitro in childhood acute lymphoblastic leukemia.
Topics: Cell Count; Cell Transformation, Neoplastic; Child; Child, Preschool; Cytarabine; Drug Resistance, Neoplasm; Humans; Interleukin-3; Interleukin-7; Lymphokines; Mitotic Index; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Thioguanine | 1999 |
Early allogeneic transplantation for refractory or relapsed acute leukaemia following remission induction with FLAG.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Transplantation, Homologous; Vidarabine | 1999 |
Salvage therapy of refractory and relapsed acute leukemia with high dose mitoxantrone and high dose cytarabine.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Salvage Therapy; Survival Rate; Treatment Outcome | 1999 |
Wilms' tumour gene (wt1) expression at diagnosis has no prognostic relevance in childhood acute lymphoblastic leukaemia treated by an intensive chemotherapy protocol.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow; Cyclophosphamide; Cytarabine; Daunorubicin; Disease-Free Survival; DNA-Binding Proteins; Female; Gene Expression Regulation, Leukemic; Genes, Wilms Tumor; Humans; Life Tables; Male; Mercaptopurine; Methotrexate; Neoplasm Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Remission Induction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Transcription Factors; Vincristine; WT1 Proteins | 1999 |
BCL-2 expression in childhood leukemia versus spontaneous apoptosis, drug induced apoptosis, and in vitro drug resistance.
Topics: Apoptosis; Bone Marrow Cells; Cells, Cultured; Child; Cytarabine; Dexamethasone; Drug Resistance, Multiple; Flow Cytometry; Gene Expression Regulation, Neoplastic; Genes, bcl-2; Humans; Leukocytes, Mononuclear; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Proto-Oncogene Proteins c-bcl-2 | 1999 |
Effects of CSFS and their combinations with chemotherapeutic agents (CH) on leukemic blasts (LB) in children (MTT-assay).
Topics: Adolescent; Adult; Antineoplastic Agents; Blast Crisis; Bone Marrow Cells; Child; Child, Preschool; Colony-Stimulating Factors; Cytarabine; Doxorubicin; Drug Screening Assays, Antitumor; Drug Synergism; Etoposide; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Infant; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1999 |
[Acute leukemia in Jehovah's Witnesses].
Topics: Adult; Anemia; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Blood Transfusion; Christianity; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Fatal Outcome; Female; Humans; Male; Mercaptopurine; Methotrexate; Personnel, Hospital; Physician-Patient Relations; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prednisone; Refusal to Treat; Remission Induction; Right to Die; Treatment Refusal; Vincristine | 1999 |
Rapid molecular response during early induction chemotherapy predicts a good outcome in childhood acute lymphoblastic leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Gene Rearrangement; Humans; Infant; Male; Mercaptopurine; Methotrexate; Neoplasm, Residual; Neoplastic Stem Cells; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Risk; Time Factors; Treatment Outcome; Vincristine | 2000 |
[The efficacy of BFM-90 program in the treatment of acute lymphoblastic leukemia in children in the studies of Polish pediatric leukemia/lymphoma group].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Infant; Male; Mercaptopurine; Methotrexate; Neoplasm Recurrence, Local; Poland; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Retrospective Studies; Survival Rate; Treatment Outcome; Vincristine | 1998 |
[The analysis of failures in the treatment of children with non-B non-Hodgkin's lymphoma. Polish pediatric leukemia/lymphoma study group report].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Humans; Infant; Lymphoma, Non-Hodgkin; Male; Mercaptopurine; Methotrexate; Neoplasm Staging; Poland; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Retrospective Studies; Survival Rate; Treatment Failure; Vincristine | 1998 |
High-dose cytarabine-based therapy in adults with acute lymphoblastic leukemia.
Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Treatment Outcome | 2000 |
Cellular cytotoxic drug sensitivity in children with acute leukemia and Down's syndrome: an explanation to differences in clinical outcome?
Topics: Antineoplastic Agents; Blast Crisis; Cell Survival; Child; Cytarabine; Dexamethasone; Down Syndrome; Doxorubicin; Etoposide; Humans; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Thioguanine; Treatment Outcome; Tumor Cells, Cultured | 2000 |
Cytotoxicity, cell-cycle perturbations and apoptosis in human tumor cells by lipophilic N4-alkyl-1-beta-D-arabinofuranosylcytosine derivatives and the new heteronucleoside phosphate dimer arabinocytidylyl-(5'-->5')-N4-octadecyl-1-beta-D-arabinofuranosylcy
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Cycle; Cytarabine; Deoxycytidine Kinase; Dimerization; Disease Models, Animal; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Mice; Mice, Nude; Phosphates; Phosphorylation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prodrugs; Transplantation, Heterologous | 2000 |
Lung toxicity following fludarabine, cytosine arabinoside and mitoxantrone (flan) treatment for acute leukemia.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Hemorrhage; Humans; Infant, Newborn; Leukemia; Leukemia, Myeloid, Acute; Lung Diseases; Male; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Respiratory Distress Syndrome, Newborn; Staphylococcal Infections; Vidarabine | 2000 |
Clinical importance of minimal residual disease in childhood acute lymphoblastic leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Daunorubicin; Etoposide; Female; Flow Cytometry; Humans; Hydrocortisone; Immunophenotyping; Infant; Male; Mercaptopurine; Methotrexate; Neoplasm, Residual; Neoplastic Cells, Circulating; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Prospective Studies; Remission Induction; Treatment Outcome; Vincristine | 2000 |
In vitro drug resistance profiles of adult versus childhood acute lymphoblastic leukaemia.
Topics: Adolescent; Adult; Age Factors; Antineoplastic Agents; Asparaginase; Bone Marrow Cells; Child; Child, Preschool; Cytarabine; Daunorubicin; Dexamethasone; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Idarubicin; Ifosfamide; Infant; Leukemia, Prolymphocytic; Leukemia, T-Cell; Male; Mercaptopurine; Middle Aged; Mitoxantrone; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Statistics, Nonparametric; Teniposide; Thioguanine; Vincristine | 2000 |
White matter changes on MRI during treatment in children with acute lymphoblastic leukemia: correlation with neuropsychological findings.
Topics: Adolescent; Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Brain Injuries; Child; Child, Preschool; Cytarabine; Demyelinating Diseases; Female; Humans; Injections, Spinal; Magnetic Resonance Imaging; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Radiotherapy, Adjuvant; Statistics, Nonparametric | 2000 |
TBI, etoposide and cyclophosphamide as a promising conditioning regimen for BMT in childhood ALL in second remission.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Cyclophosphamide; Cytarabine; Etoposide; Female; Humans; Idarubicin; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Transplantation Conditioning; Whole-Body Irradiation | 2000 |
Aseptic meningitis in a child after systemic treatment with high dose cytarabine.
Topics: Antimetabolites, Antineoplastic; Child; Cytarabine; Female; Humans; Meningitis, Aseptic; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2001 |
[Changes of thyroid and adrenocortical functions after bone marrow transplantation with MAC conditioning regimen in leukemia patients].
Topics: Adolescent; Adrenal Cortex; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Cyclophosphamide; Cytarabine; Female; Humans; Male; Melphalan; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Thyroid Gland; Transplantation Conditioning | 1998 |
[Outcome of autologous bone marrow transplantation in 73 patients with acute leukemia].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Melphalan; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Transplantation Conditioning; Transplantation, Autologous; Treatment Outcome | 1998 |
Total body irradiation before allogeneic bone marrow transplantation: is more dose better?
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radiation-Sensitizing Agents; Radiotherapy Dosage; Retrospective Studies; Thiotepa; Transplantation Conditioning; Transplantation, Homologous; Whole-Body Irradiation | 2001 |
[Philadelphia chromosome-positive acute lymphoblastic leukemia with monosomy 7 successfully treated with intermediate- and high-dose ara-C].
Topics: Antimetabolites, Antineoplastic; Chromosomes, Human, Pair 7; Cytarabine; Humans; Male; Middle Aged; Monosomy; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2001 |
Outcome of relapsed or refractory childhood B-cell acute lymphoblastic leukaemia and B-cell non-Hodgkin's lymphoma treated with the UKCCSG 9003/9002 protocols.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Burkitt Lymphoma; Child; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Follow-Up Studies; Humans; Lymphoma, B-Cell; Palliative Care; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Recurrence; Treatment Outcome; Vincristine | 2001 |
Early onset Pneumocystis carinii pneumonia after allogeneic peripheral blood stem cell transplantation.
Topics: Antibiotic Prophylaxis; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Combined Modality Therapy; Cytarabine; Daunorubicin; Etoposide; Fatal Outcome; Hematopoietic Stem Cell Transplantation; Humans; Immune System; Immunocompromised Host; Male; Methotrexate; Middle Aged; Opportunistic Infections; Pneumonia, Pneumocystis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Respiratory Insufficiency; Transplantation Conditioning; Transplantation, Autologous; Trimethoprim, Sulfamethoxazole Drug Combination; Vincristine; Whole-Body Irradiation | 2001 |
Interaction of cytosine arabinoside and lovastatin in human leukemia cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Division; Cytarabine; Drug Synergism; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; K562 Cells; Lovastatin; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Precursor Cell Lymphoblastic Leukemia-Lymphoma; ras Proteins | 2001 |
Magnetic resonance imaging detection of avascular necrosis of the bone in children receiving intensive prednisone therapy for acute lymphoblastic leukemia or non-Hodgkin lymphoma.
Topics: Adolescent; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Arthralgia; Arthroplasty, Replacement, Hip; Asparaginase; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Etoposide; Female; Femur Head Necrosis; Humans; Lymphoma, Non-Hodgkin; Magnetic Resonance Imaging; Male; Mercaptopurine; Methotrexate; Mitoxantrone; Osteonecrosis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Risk Factors; Treatment Outcome; Vincristine | 2001 |
High level resistance to glucocorticoids, associated with a dysfunctional glucocorticoid receptor, in childhood acute lymphoblastic leukemia cells selected for methotrexate resistance.
Topics: Active Transport, Cell Nucleus; Alleles; Antineoplastic Agents; Child; Cytarabine; Dexamethasone; DNA Mutational Analysis; DNA, Neoplasm; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Glucocorticoids; Humans; Leukemia, T-Cell; Methotrexate; Neoplasm Proteins; Neoplastic Stem Cells; Polymorphism, Restriction Fragment Length; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Binding; Receptors, Glucocorticoid; RNA, Messenger; RNA, Neoplasm; Selection, Genetic; Sequence Analysis, DNA; Tumor Cells, Cultured | 2001 |
[Treatment of acute lymphoblastic leukemia in adults as an unsolved problem].
Topics: Adolescent; Adult; Age Factors; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cyclophosphamide; Cytarabine; Dexamethasone; Humans; Mercaptopurine; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Risk Factors; Time Factors; Vincristine | 2001 |
Repetitious appearance and disappearance of different kinds of clonal cytogenetic abnormalities after allogeneic bone marrow transplantation.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Child, Preschool; Chromosome Aberrations; Chromosome Disorders; Clone Cells; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; DNA Damage; Female; Follow-Up Studies; Humans; In Situ Hybridization, Fluorescence; Karyotyping; Mercaptopurine; Methotrexate; Methylprednisolone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction; Time Factors; Transplantation Conditioning; Transplantation, Homologous; Vincristine | 2001 |
Bone marrow stromal cells regulate caspase 3 activity in leukemic cells during chemotherapy.
Topics: Acute Disease; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Bone Marrow Cells; Caspase 3; Caspases; Cell Survival; Coculture Techniques; Cytarabine; Etoposide; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stromal Cells; Tumor Cells, Cultured | 2001 |
MR findings in Balint's syndrome, following intrathecal methotrexate and cytarabine therapy in adult acute lymphoblastic leukemia.
Topics: Adult; Brain; Cytarabine; Drug Therapy, Combination; Female; Humans; Injections, Spinal; Magnetic Resonance Imaging; Methotrexate; Neurologic Examination; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Psychomotor Disorders; Syndrome | 2001 |
Treatment of relapse after allogeneic bone marrow transplantation with reduced intensity conditioning (FLAG +/- Ida) and second allogeneic stem cell transplant.
Topics: Acute Disease; Adult; Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Disease-Free Survival; Female; Filgrastim; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia; Leukemia, Myeloid; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recombinant Proteins; Recurrence; Reoperation; Retrospective Studies; Survival Rate; Transplantation Conditioning; Transplantation, Homologous; Vidarabine | 2001 |
Ventral polyradiculopathy with pediatric acute lymphocytic leukemia.
Topics: Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Cytarabine; Electromyography; Female; Humans; Hydrocortisone; Injections, Spinal; Magnetic Resonance Imaging; Methotrexate; Polyradiculopathy; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2002 |
Different drug sensitivity profiles of acute myeloid and lymphoblastic leukemia and normal peripheral blood mononuclear cells in children with and without Down syndrome.
Topics: Amsacrine; Anthracyclines; Antineoplastic Agents; Busulfan; Cell Survival; Child; Child, Preschool; Cytarabine; Down Syndrome; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Etoposide; Female; Humans; Infant; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Thioguanine; Vincristine | 2002 |
Late effects of anticancer therapy on kidney function in children with acute lymphoblastic leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Infant; Kidney; Kidney Function Tests; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Vincristine | 2001 |
[Effective treatment with Lamivudine of patients with reactivation of hepatitis B following chemotherapy administration].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Female; Hepatitis B; Hepatitis B virus; Humans; Lamivudine; Leukemia-Lymphoma, Adult T-Cell; Male; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Reverse Transcriptase Inhibitors; Vincristine; Virus Activation | 2001 |
Cytotoxicity of 2-chlorodeoxyadenosine and arabinosylcytosine in leukaemic lymphoblasts from paediatric patients: significance of cellular nucleoside transporter content.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Carrier Proteins; Cell Survival; Child; Cladribine; Cytarabine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Humans; Immunophenotyping; Lymphocytes; Membrane Proteins; Nucleoside Transport Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Cells, Cultured | 2002 |
Magnetic resonance imaging findings in a case of cytarabine-induced myelopathy.
Topics: Adult; Cytarabine; Humans; Immunosuppressive Agents; Injections, Spinal; Magnetic Resonance Imaging; Male; Military Personnel; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Quadriplegia; Spinal Cord Diseases | 2002 |
Long-term follow-up of intensive ara-C-based chemotherapy followed by bone marrow transplantation for adult acute lymphoblastic leukemia: impact of induction Ara-C dose and post-remission therapy.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Bone Marrow Transplantation; Cytarabine; Follow-Up Studies; Humans; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Transplantation, Autologous | 2002 |
The role of high-dose cytarabine in induction therapy for adult ALL.
Topics: Adult; Antimetabolites, Antineoplastic; Cytarabine; Hematopoietic Stem Cell Transplantation; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2002 |
Cyclopentenyl cytosine increases the phosphorylation and incorporation into DNA of 1-beta-D-arabinofuranosyl cytosine in a human T-lymphoblastic cell line.
Topics: Antineoplastic Agents; Apoptosis; Cell Division; Cytarabine; Cytidine; Cytidine Triphosphate; Deoxycytosine Nucleotides; DNA; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Humans; Phosphorylation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Time Factors; Tumor Cells, Cultured | 2002 |
No major cognitive impairment in young children with acute lymphoblastic leukemia using chemotherapy only: a prospective longitudinal study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Attention; Child, Preschool; Cognition Disorders; Cyclophosphamide; Cytarabine; Dexamethasone; Female; Follow-Up Studies; Humans; Ifosfamide; Injections, Spinal; Learning Disabilities; Longitudinal Studies; Male; Mercaptopurine; Methotrexate; Netherlands; Neuropsychological Tests; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prospective Studies; Survivors; Teniposide; Treatment Outcome; Vincristine | 2002 |
Pediatric acute lymphoblastic leukemia: redefining outcomes.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Attention; Child; Child, Preschool; Cognition Disorders; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Dexamethasone; Drug Administration Routes; Humans; Hydrocortisone; Infant; Learning Disabilities; Memory Disorders; Methotrexate; Neuropsychological Tests; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Survivors; Treatment Outcome | 2002 |
Expression of P53 and bcl-2 proteins in T-cell lymphoblastic lymphoma: prognostic implications.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Disease-Free Survival; Etoposide; Female; Humans; Ifosfamide; Immunohistochemistry; Logistic Models; Longitudinal Studies; Male; Methotrexate; Neoplasm Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Proto-Oncogene Proteins c-bcl-2; Recurrence; Retrospective Studies; Survival Analysis; Tumor Suppressor Protein p53; Vincristine | 2002 |
CD56 expression predicts occurrence of CNS disease in acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Marrow Cells; CD56 Antigen; Cell Adhesion; Central Nervous System; Chemotaxis, Leukocyte; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Disease-Free Survival; Doxorubicin; Female; Gene Expression; Humans; Incidence; Leukemic Infiltration; Life Tables; Male; Mercaptopurine; Methotrexate; Middle Aged; Neoplasm Proteins; Neoplastic Stem Cells; Neurons; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Predictive Value of Tests; Prednisone; Risk; Survival Analysis; Treatment Outcome; Vincristine | 2002 |
Intensified and shortened cyclical chemotherapy for adult acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Administration Schedule; Etoposide; Female; Humans; Immunophenotyping; Male; Mercaptopurine; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Risk Factors; Treatment Outcome; Vincristine | 2002 |
[High risk acute lymphoblastic leukaemia in children. Preliminary report after introducing a new version of New York (1997) protocol adjusted to the age of the patients. Report of the Polish Paediatric Leukaemia/Lymphoma Study Group].
Topics: Adolescent; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Infant; Infant, Newborn; Male; Methotrexate; Multicenter Studies as Topic; Poland; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Retrospective Studies; Risk Factors; Thioguanine; Time Factors; Treatment Outcome; Vincristine | 2000 |
Urate-oxidase in the prevention and treatment of metabolic complications in patients with B-cell lymphoma and leukemia, treated in the Société Française d'Oncologie Pédiatrique LMB89 protocol.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Female; France; Humans; Hydrocortisone; Leucovorin; Lymphoma, B-Cell; Male; Methotrexate; Neoplasm Staging; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Retrospective Studies; Risk Assessment; Sensitivity and Specificity; Survival Rate; Treatment Outcome; Tumor Lysis Syndrome; Urate Oxidase; Vincristine | 2002 |
Cytomegalovirus infection in children with blood diseases.
Topics: Adolescent; Anemia, Aplastic; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Cytomegalovirus Infections; Daunorubicin; Female; gamma-Globulins; Humans; Immune Tolerance; Immunization, Passive; Infant; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Methotrexate; Opportunistic Infections; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Thioguanine; Vincristine | 1992 |
Acute bilateral parotitis during chemotherapy for acute lymphoblastic leukemia.
Topics: Acute Disease; Adult; Ancitabine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Male; Parotitis; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1992 |
[Treatment of various types of acute leukemia in adult. An analysis of 98 cases. The Leukemia Cooperation Group of Beijing City].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Vincristine | 1992 |
[The programmed therapy of acute lymphoblastic leukemia in adults].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Evaluation; Humans; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Recurrence; Remission Induction; Vincristine | 1992 |
Treatment of primary refractory or relapsed acute lymphoblastic leukemia (ALL) in children.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Female; Follow-Up Studies; Humans; Idarubicin; Infant; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction | 1992 |
Differences in the intracellular pharmacokinetics of cytosine arabinoside (AraC) between circulating leukemic blasts and normal mononuclear blood cells.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Arabinofuranosyluracil; Cytarabine; Daunorubicin; Drug Administration Schedule; Humans; Leukemia, Myeloid; Leukocytes, Mononuclear; Lymphoma, Non-Hodgkin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Thioguanine | 1992 |
Analysis of growth failure in children treated for acute lymphoblastic leukemia.
Topics: Adolescent; Anthropometry; Antineoplastic Combined Chemotherapy Protocols; Body Height; Child; Child, Preschool; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Cytarabine; Doxorubicin; Female; Growth Disorders; Humans; Incidence; Infant; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Puberty, Delayed; Radiation Injuries; Remission Induction; Risk Factors | 1992 |
[Evaluation of 58 patients with acute leukemia].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction; Retrospective Studies; Survival Rate; Treatment Outcome | 1992 |
[High dose cinobufocini in attenuation and treatment of infection and granulocytopenia during combined chemotherapy of malignant blood diseases].
Topics: Adolescent; Adult; Aged; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Bufanolides; Cyclophosphamide; Cytarabine; Female; Humans; Infection Control; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Vincristine | 1992 |
Management of children with acute lymphoblastic leukemia by the Dana-Farber Cancer Institute protocols. An update of the Ontario experience.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cohort Studies; Cranial Irradiation; Cytarabine; Daunorubicin; Doxorubicin; Humans; Infant; Life Tables; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prospective Studies; Remission Induction; Risk; Survival Analysis; Survival Rate; Treatment Outcome; Vincristine | 1992 |
Clustering of adverse drug events: analysis of risk factors for cerebellar toxicity with high-dose cytarabine.
Topics: Adolescent; Adult; Aged; Cerebellar Diseases; Cerebellum; Cohort Studies; Creatinine; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Risk Factors | 1992 |
Four-agent induction/consolidation therapy for childhood acute lymphoblastic leukemia: an Indian experience.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Doxorubicin; Female; Humans; India; Male; Multivariate Analysis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Remission Induction; Vincristine | 1992 |
Meningeal fluid granulocytosis after cytarabine.
Topics: Adult; Cerebrospinal Fluid; Cytarabine; Granulocytes; Humans; Male; Meningitis; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1992 |
Therapy of acute lymphoblastic leukemia in adults.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Burkitt Lymphoma; Combined Modality Therapy; Cytarabine; Drug Administration Schedule; Hematopoietic Cell Growth Factors; Humans; Leukemia-Lymphoma, Adult T-Cell; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction | 1992 |
Mitoxantrone and continuous infusion of cytosine arabinoside in refractory and relapsed acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Male; Mitoxantrone; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction | 1992 |
Phenotypic analysis of 1-B-D-arabinofuranosylcytosine deamination in patients treated with high doses and correlation with response.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arabinofuranosyluracil; Cytarabine; Deamination; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Phenotype; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Serum Albumin, Bovine; Sex Factors | 1992 |
An HIV positive haemophiliac with acute lymphoblastic leukaemia successfully treated with intensive chemotherapy and syngeneic bone marrow transplantation.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Hemophilia A; HIV Seropositivity; Humans; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1992 |
The combination of quercetin and cytosine arabinoside synergistically inhibits leukemic cell growth.
Topics: Acute Disease; Cell Division; Cytarabine; Drug Synergism; Humans; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Quercetin; Receptors, Estrogen; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1992 |
1-beta-D-arabinofuranosylcytosine (Ara-C) enhances mitochondrial activities in human leukaemic cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Cell Cycle; Cell Line; Cytarabine; DNA Probes; DNA, Neoplasm; Electron Transport Complex IV; Flow Cytometry; G1 Phase; Humans; Kinetics; Mitochondria; Neoplasm Proteins; Oxygen Consumption; Precursor Cell Lymphoblastic Leukemia-Lymphoma; S Phase | 1991 |
Behavioral effects of corticosteroids in children with acute lymphoblastic leukemia.
Topics: Age Factors; Analysis of Variance; Attention; Child; Child Behavior; Child, Preschool; Cytarabine; Depression; Doxorubicin; Drug Interactions; Emotions; Female; Humans; Infant; Interpersonal Relations; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prospective Studies; Sex Factors; Sleep; Vincristine | 1992 |
[A study of combination chemotherapy (BHAC-ACVP) for adult acute lymphocytic leukemia. Hanshin Co-operative Study Group of Hematological Malignancies].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Administration Schedule; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction; Survival Rate; Vindesine | 1992 |
Treatment of relapsed or refractory adult acute lymphocytic leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Recurrence; Remission Induction; Vindesine | 1992 |
Unexpected acute neurologic toxicity in the treatment of children with acute lymphoblastic leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cytarabine; Etoposide; Female; Humans; Infant; Leucovorin; Male; Methotrexate; Nervous System Diseases; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1992 |
Intensive chemotherapy with mitoxantrone and high-dose cytosine arabinoside followed by granulocyte-macrophage colony-stimulating factor in the treatment of patients with acute lymphocytic leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Fever; Granulocyte-Macrophage Colony-Stimulating Factor; Granulocytes; Humans; Infections; Leukopenia; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Remission Induction; Salvage Therapy; Survival Rate | 1992 |
Somnolence, hypotension, and metabolic acidosis following high-dose teniposide treatment in children with leukemia.
Topics: Acidosis; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Diphenhydramine; Drug Administration Schedule; Female; Humans; Hypotension; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Sleep Wake Disorders; Teniposide | 1991 |
Skin manifestation of extramedullary relapse in adult with acute lymphoblastic leukaemia.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cyclophosphamide; Cytarabine; Doxorubicin; Female; Humans; Immunotherapy; Leukemic Infiltration; Mercaptopurine; Methotrexate; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Radiotherapy; Recurrence; Remission Induction; Skin; Vincristine | 1991 |
Plasma and cerebrospinal fluid pharmacokinetics of 1-beta-D-arabinofuranosylcytosine and 1-beta-D-arabinofuranosyluracil following the repeated intravenous administration of high- and intermediate-dose 1-beta-D-arabinofuranosylcytosine.
Topics: Adult; Arabinofuranosyluracil; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Regression Analysis | 1991 |
Amsacrine is safe and effective therapy for patients with myocardial dysfunction and acute leukemia.
Topics: Amsacrine; Cardiac Output, Low; Cytarabine; Drug Therapy, Combination; Humans; Leukemia; Leukemia, Myeloid, Acute; Myocardium; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Stroke Volume | 1991 |
Short course high dose mitoxantrone with high dose cytarabine is effective therapy for adult lymphoblastic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1991 |
The F-MACHOP regimen in advanced diffuse aggressive lymphomas: summary of ten years' experience at a single institution.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Doxorubicin; Fluorouracil; Humans; Leucovorin; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Vincristine | 1991 |
Bone marrow transplant retinopathy.
Topics: Adolescent; Adult; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Dose-Response Relationship, Radiation; Female; Follow-Up Studies; Humans; Incidence; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radiotherapy; Retinal Diseases; Visual Acuity | 1991 |
Bulbar and pseudobulbar palsy complicating therapy with high-dose cytosine arabinoside in children with leukemia.
Topics: Adolescent; Bulbar Palsy, Progressive; Cerebellar Ataxia; Child; Cytarabine; Female; Humans; Injections, Intravenous; Jaundice; Leukemia, Myelomonocytic, Acute; Leukemia, Promyelocytic, Acute; Male; Paralysis; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1991 |
Rare neurotoxicity related to intrathecal Cytosar.
Topics: Adult; Cytarabine; Female; Humans; Injections, Spinal; Nervous System Diseases; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1991 |
Structure-activity relationships of cadeguomycin analogs.
Topics: Anti-Bacterial Agents; Cell Count; Cell Division; Cytarabine; Cytosine Nucleotides; Drug Synergism; Guanosine; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Molecular Structure; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Structure-Activity Relationship; Tumor Cells, Cultured | 1991 |
Memory and learning sequelae in long-term survivors of acute lymphoblastic leukemia: association with attention deficits.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Attention; Brain Diseases; Calcinosis; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Humans; Injections, Spinal; Learning Disabilities; Memory Disorders; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radiotherapy, High-Energy; Tomography, X-Ray Computed; Verbal Learning | 1990 |
Prognosis of acute lymphoblastic leukaemia in Ibadan, Nigeria.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Drug Combinations; Hospitals, University; Humans; Nigeria; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Remission Induction; Risk Factors; Survival Rate; Vincristine | 1990 |
Acute respiratory failure after intrathecal methotrexate administration.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Doxorubicin; Female; Humans; Infant; Injections, Spinal; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Respiratory Insufficiency; Teniposide | 1990 |
High dose cytosine arabinoside in the initial treatment of adults with acute lymphoblastic leukaemia.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Humans; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction; Vincristine | 1990 |
Successful treatment of acute leukemia with t(4;11) in an infant with congenital hypothyroidism.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Differentiation; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 4; Congenital Hypothyroidism; Cranial Irradiation; Cytarabine; Doxorubicin; Etoposide; Female; Humans; Hypothyroidism; Infant; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction; Translocation, Genetic; Vincristine | 1990 |
Multiagent chemotherapy in relapsed acute lymphoblastic leukemia in children.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cytarabine; Daunorubicin; Female; Humans; Hydrocortisone; Infant; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Recurrence; Remission Induction; Teniposide; Vincristine | 1990 |
Flow cytometry DNA measurement for prediction of effect of therapy in acute leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; DNA, Neoplasm; Flow Cytometry; Humans; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis | 1990 |
In vitro drug sensitivity of cells from children with leukemia using the MTT assay with improved culture conditions.
Topics: Asparaginase; Cells, Cultured; Child; Coloring Agents; Culture Media; Cyclophosphamide; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Resistance; Drug Screening Assays, Antitumor; Humans; Mechlorethamine; Mercaptopurine; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Tetrazolium Salts; Thiazoles; Thioguanine; Vincristine | 1990 |
'MACHO' chemotherapy for stage IV B cell lymphoma and B cell acute lymphoblastic leukaemia of childhood. United Kingdom Children's Cancer Study Group (UKCCSG).
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Doxorubicin; Female; Humans; Leucovorin; Lymphoma, B-Cell; Lymphoma, Non-Hodgkin; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Vincristine | 1990 |
Septicemia due to Streptococcus mitis in neutropenic patients with acute leukemia.
Topics: Adult; Cytarabine; Disseminated Intravascular Coagulation; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neutropenia; Penicillin G; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Quinolines; Respiratory Distress Syndrome; Sepsis; Streptococcal Infections | 1990 |
Mitoxantrone and high-dose cytosine arabinoside for the treatment of refractory acute lymphocytic leukemia.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Male; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Survival Rate | 1990 |
Low-dose cytosine arabinoside in relapsed acute lymphocytic leukemia.
Topics: Adolescent; Adult; Child; Cytarabine; Female; Humans; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction | 1990 |
Pharmacokinetics of cytosine arabinoside in cerebrospinal fluid and of its metabolite in leukemic cells.
Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Catheterization; Child; Cytarabine; Female; Humans; Hydrocortisone; Injections, Intraventricular; Lumbar Vertebrae; Meningeal Neoplasms; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Time Factors | 1990 |
Continuous infusion of mitoxantrone combined with high-dose cytarabine in refractory/relapsed acute myeloblastic leukemia and blast crisis of chronic myelogenous leukemia.
Topics: Adolescent; Adult; Aged; Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; Austria; Blast Crisis; Cytarabine; Drug Evaluation; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1990 |
Effective prevention of central nervous system leukemia with intrathecal methotrexate and intrathecal methotrexate, cytosine arabinoside, and hydrocortisone in childhood acute lymphocytic leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Brain Neoplasms; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Drug Evaluation; Female; Humans; Hydrocortisone; Infant; Injections, Spinal; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Spinal Cord Neoplasms; Testicular Neoplasms | 1990 |
Colony-stimulating factors (rhG-CSF, rhGM-CSF, rhIL-3, and BCGF) recruit myeloblastic and lymphoblastic leukemic cells and enhance the cytotoxic effects of cytosine-arabinoside.
Topics: Adult; Blast Crisis; Cell Cycle; Child; Colony-Stimulating Factors; Cytarabine; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Interleukin-4; Leukemia, Myeloid; Neoplastic Stem Cells; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recombinant Proteins; Tumor Cells, Cultured | 1990 |
Serum immunoreactive erythropoietin in children with acute leukaemia at various stages of disease--and the effects of treatment.
Topics: Adolescent; Anemia; Child; Child, Preschool; Cytarabine; Dose-Response Relationship, Drug; Erythropoietin; Female; Hemoglobins; Humans; Infant; Leukemia, Myeloid, Acute; Longitudinal Studies; Lymphoma, Non-Hodgkin; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1990 |
High-dose cytosine arabinoside and mitoxantrone in previously-treated acute leukemia patients.
Topics: Adolescent; Adult; Aged; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Infusions, Intravenous; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1990 |
[Transverse leukonychia and anti-leukemia chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Child, Preschool; Cyclophosphamide; Cytarabine; Humans; Male; Methotrexate; Nail Diseases; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Vincristine | 1990 |
[Effects of recombinant human granulocyte colony stimulating factor following high-dose cytosine arabinoside therapy in children with malignancy].
Topics: Child; Child, Preschool; Colony-Stimulating Factors; Cytarabine; Female; Granulocytes; Histiocytosis; Humans; Infant; Lymphoma, Non-Hodgkin; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recombinant Proteins | 1990 |
Successful treatment of adult acute lymphoblastic leukemia after relapse with prednisone, intermediate-dose cytarabine, mitoxantrone, and etoposide (PAME) chemotherapy.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Drug Administration Schedule; Etoposide; Female; Humans; Male; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Recurrence; Remission Induction; Survival Rate | 1990 |
[Multi-agent combination chemotherapy for adult acute lymphoblastic leukemia--individualized chemotherapy].
Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Drug Administration Schedule; Etoposide; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction; Survival Rate; Vindesine | 1990 |
Treatment of refractory acute lymphoblastic leukemia in adults with high dose cytosine arabinoside and mitoxantrone (HAM).
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Diarrhea; Drug Evaluation; Female; Humans; Male; Middle Aged; Mitoxantrone; Nausea; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Vomiting | 1990 |
Pharmacodynamic and DNA methylation studies of high-dose 1-beta-D-arabinofuranosyl cytosine before and after in vivo 5-azacytidine treatment in pediatric patients with refractory acute lymphocytic leukemia.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Azacitidine; Child; Child, Preschool; Cytarabine; Deoxycytidine Kinase; DNA, Neoplasm; Drug Resistance; Drug Screening Assays, Antitumor; Female; Gene Expression Regulation; Humans; Male; Methylation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Tumor Cells, Cultured | 1989 |
The role of peripheral blood stem cells as rescue after myeloablative therapy.
Topics: Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Blood Transfusion; Combined Modality Therapy; Cytarabine; Daunorubicin; Evaluation Studies as Topic; Graft Survival; Hematopoietic Stem Cell Transplantation; Humans; Leukapheresis; Leukemia, Myeloid, Acute; Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Transplantation, Autologous | 1989 |
Idarubicin in combination with intermediate-dose cytarabine in the treatment of refractory or relapsed acute leukemias.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Idarubicin; Leukemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1989 |
Bacteraemia caused by Stomatococcus mucilaginosus in a granulocytopenic patient with acute lymphocytic leukaemia.
Topics: Adult; Agranulocytosis; Amsacrine; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Ciprofloxacin; Cytarabine; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sepsis | 1989 |
Characterization of nucleoside transport during leukemic cell differentiation.
Topics: Biological Transport; Cell Differentiation; Cytarabine; Deoxycytidine Kinase; Dipyridamole; Humans; Inosine; Leukemia, Promyelocytic, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thioinosine; Tretinoin; Tumor Cells, Cultured | 1989 |
Flow cytometric determination with bromodeoxyuridine/DNA assay of sensitivity of S-phase cells to cytosine arabinoside in childhood acute lymphoblastic leukemia.
Topics: Adolescent; Antibodies, Monoclonal; Bone Marrow; Bone Marrow Cells; Bromodeoxyuridine; Cell Separation; Child; Child, Preschool; Cytarabine; DNA; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Flow Cytometry; Humans; Interphase; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1989 |
Phenotype switch in acute leukemia patients after intensive chemotherapy.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Phenotype; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1989 |
Reinduction therapy for advanced or refractory acute lymphoblastic leukemia of childhood.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Drug Administration Schedule; Female; Humans; Infant; Male; Methotrexate; Mycoses; Platelet Count; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Vincristine | 1989 |
Treatment of relapsed and refractory acute leukaemia with high-dose cytosine arabinoside and etoposide.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence | 1989 |
Development of resistance to 1-beta-D-arabinofuranosylcytosine after high-dose treatment in childhood lymphoblastic leukemia: analysis of resistance mechanism in established cell lines.
Topics: Arabinofuranosylcytosine Triphosphate; Arabinofuranosyluracil; Child; Cytarabine; Drug Resistance; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Time Factors; Tumor Cells, Cultured | 1989 |
Respiratory insufficiency in acute leukemia following treatment with cytosine arabinoside and septicemia with streptococcus viridans.
Topics: Acute Disease; Adult; Cytarabine; Female; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Respiratory Insufficiency; Sepsis; Streptococcal Infections | 1989 |
A study of the mechanisms of cytotoxicity of Ara-C on three human leukemic cell lines.
Topics: Arabinofuranosylcytosine Triphosphate; Cytarabine; Deoxycytidine Kinase; Deoxycytosine Nucleotides; DNA; DNA Ligases; DNA Polymerase II; DNA, Neoplasm; Humans; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Promyelocytic, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1989 |
Clinical significance of fibrinopeptide A in acute lymphocytic and non-lymphocytic leukaemia.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Daunorubicin; Disseminated Intravascular Coagulation; Female; Fibrinogen; Fibrinopeptide A; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Longitudinal Studies; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radioimmunoassay; Thioguanine; Time Factors | 1989 |
Reversible treatment-related leukoencephalopathy.
Topics: Child; Child, Preschool; Cytarabine; Drug Synergism; Drug Therapy, Combination; Humans; Leukoencephalopathy, Progressive Multifocal; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1989 |
Acute leukemia presenting as a unilateral exudative retinal detachment.
Topics: Biopsy; Blood Cell Count; Bone Marrow Examination; Child; Cytarabine; Fluorescein Angiography; Humans; Hydrocortisone; Injections, Spinal; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retinal Detachment; Visual Acuity | 1989 |
Inappropriate increase in erythropoietin titers during chemotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Asparaginase; Cyclophosphamide; Cytarabine; Daunorubicin; Erythropoietin; Female; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Vincristine | 1989 |
Low-dose cytosine arabinoside as remission induction therapy in refractory adult acute lymphocytic leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Male; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction | 1989 |
Intravenous immunoglobulin may lessen all forms of infection in patients receiving allogeneic bone marrow transplantation for acute lymphoblastic leukemia: a pediatric oncology group study.
Topics: Bone Marrow Transplantation; Child; Cytarabine; Graft Survival; Humans; Immunization, Passive; Immunoglobulins; Injections, Intravenous; Opportunistic Infections; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Transplantation, Homologous | 1988 |
[Intravenous immunoglobulin preparations in the adjuvant treatment of acute lymphoblastic leukemia in children].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Doxorubicin; Humans; Immunization, Passive; Immunoglobulin G; Immunoglobulins, Intravenous; Infant; Infusions, Intravenous; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Thioguanine; Vincristine | 1988 |
High-dose methotrexate therapy (6-8 g/m2) in childhood malignancies: clinical tolerability and pharmacokinetics.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Evaluation; Half-Life; Humans; Infusions, Intravenous; Leucovorin; Lymphoma, Non-Hodgkin; Metabolic Clearance Rate; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Stomatitis; Vincristine | 1987 |
[BH-AC.AMP protocol in the treatment of refractory childhood acute leukemia].
Topics: Aclarubicin; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Drug Administration Schedule; Female; Humans; Infant; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Lymphoma; Male; Mercaptopurine; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction | 1988 |
[Intermediate dose of Ara-C (IDAra-C) for the treatment of refractory and relapsed lymphoid malignancies].
Topics: Adolescent; Adult; Aged; Cytarabine; Female; Humans; Leukemia-Lymphoma, Adult T-Cell; Lymphoma, Non-Hodgkin; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1988 |
Aggressive treatment improves survival in adult acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Blood Transfusion; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Evaluation; Humans; Meningeal Neoplasms; Mercaptopurine; Methotrexate; Middle Aged; Nervous System Diseases; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction; Vincristine | 1988 |
Short-term intensive treatment (V.A.A.P.) of adult acute lymphoblastic leukemia and lymphoblastic lymphoma.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Doxorubicin; Drug Evaluation; Female; Humans; Lymphoma, Non-Hodgkin; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Vincristine | 1988 |
Treatment of high-risk acute lymphoblastic leukemia with protocols PETHEMA LAL 7/78 and LAL 17/84.
Topics: Adolescent; Antineoplastic Agents; Asparaginase; Child; Child, Preschool; Clinical Protocols; Cytarabine; Daunorubicin; Female; Humans; Infant; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Vincristine | 1988 |
[Cytosine arabinoside and VM-26 in induction treatment, failures and recurrences of childhood acute lymphoblastic leukemias].
Topics: Child; Child, Preschool; Cytarabine; Drug Combinations; Female; Humans; Male; Podophyllotoxin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Risk Factors; Teniposide | 1988 |
[Acute lymphoblastic leukemia in adults: results of the DATOP-79 protocol].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Evaluation; Female; Humans; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Thioguanine; Time Factors; Vincristine | 1988 |
[Preliminary evaluation of the treatment of recurrences of acute lymphoblastic leukemia by the BFM (Henze) method].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Doxorubicin; Female; Humans; Male; Methotrexate; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Remission Induction; Thioguanine; Time Factors; Vincristine | 1988 |
[Effect of prognostic factors on the course of acute lymphoblastic leukemia in children].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Doxorubicin; Female; Humans; Infant; Leukocyte Count; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Thioguanine; Time Factors; Vincristine | 1988 |
Deoxycoformycin treatment for childhood T-cell acute lymphoblastic leukemia early in second remission: a Pediatric Oncology Group Study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Coformycin; Cytarabine; Daunorubicin; Humans; Pentostatin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Ribonucleosides; T-Lymphocytes; Teniposide; Vincristine | 1988 |
Bone marrow transplantation for advanced acute lymphoblastic leukemia in young people: a comparison of two conditioning regimens.
Topics: Adolescent; Adult; Bone Marrow Transplantation; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Dose-Response Relationship, Drug; Humans; Infant; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Whole-Body Irradiation | 1987 |