cytarabine has been researched along with Acute Disease in 1272 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 519 (40.80) | 18.7374 |
| 1990's | 347 (27.28) | 18.2507 |
| 2000's | 332 (26.10) | 29.6817 |
| 2010's | 62 (4.87) | 24.3611 |
| 2020's | 12 (0.94) | 2.80 |
| Authors | Studies |
|---|---|
| Chou, TH; Kessel, D; Khilanani, P; Lomen, PL | 1 |
| Aguilar Martínez, JC; Campos Gonzaga, L; García Martínez, A; Mateos Millán, D | 1 |
| Chen, S; Feng, L; Hao, C; Lao, Y; Li, B; Liu, N; Mack, R; Peng, M; Shao, X; Song, J; Sun, X; Wang, S; Wang, T; Wei, W; Wu, Y; Yin, L; Zhang, J; Zhang, L | 1 |
| Atchley, E; Derkach, A; DeWolf, S; Galera, PK; Glass, J; Roshal, M; Shah, R; Stump, SE; Weis, TM; Xiao, W | 1 |
| Cao, J; Chen, D; Li, S; Liu, X; Lu, Y; Pei, R; Wang, T; Xu, X; Ye, P; Zheng, ZZ | 1 |
| Chang, WI; MacDonell-Yilmaz, RE; Moynihan, L; Sampino, EV; Sprinz, PG | 1 |
| Arcese, W; Ciceri, F; Gedde-Dahl, T; Gorin, NC; Labopin, M; Lanza, F; Maertens, J; Meijer, E; Mohty, M; Montoro, J; Pabst, T; Pérez-Simón, JA; Sanz, J; Schaap, N; Van Gorkom, G; Versluis, J; Vrhovac, R | 1 |
| Beutel, G; Dammann, E; Eder, M; Eggers, H; Ehrlich, S; Gabdoulline, R; Ganser, A; Göhring, G; Hambach, L; Heuser, M; Klement, P; Koenecke, C; Markel, D; Neziri, B; Rehberg, A; Reuter, M; Schlegelberger, B; Shahswar, R; Stadler, M; Thol, F; Wichmann, M | 1 |
| Cerchione, C; Martinelli, G | 1 |
| Banavali, S; Gujral, S; Myint, HH; Narula, G; Patkar, N; Prasad, M; Subramanian, P; Tandon, S; Tembhare, P | 1 |
| Bar-Natan, M; Lancman, G; Mascarenhas, J | 1 |
| Jaramillo, S; Schlenk, RF | 1 |
| Borkhardt, A; Dilloo, D; Escherich, G; Faber, J; Feuchtinger, T; Horstmann, MA; Imschweiler, T; Jorch, N; Pekrun, A; Schmid, I; Schramm, F; Spohn, M; Zimmermann, M; Zur Stadt, U | 1 |
| Heisel, RW; Lim, SH; Mascara, GP; Oleksiuk, LM; Sutton, RR; Weber, DR; Winger, DG | 1 |
| Helleday, T; Henter, JI; Herold, N; Kutzner, J; Myrberg, IH; Olsen, TK; Paulin, CBJ; Rudd, SG; Sanjiv, K; Schaller, T | 1 |
| Inokuchi, K; Kitano, T; Miyake, K; Miyake, N; Omori, I; Yamaguchi, H | 1 |
| Chan, S; Farshchi Zarabi, S; Gupta, V; Khalaf, D; Lutynski, A; Minden, MD; Rostom, A; Rydlewski, A; Schimmer, AD; Schuh, AC; Sibai, H; Yee, KWL | 1 |
| Cubitt, C; Komrokji, RS; Lancet, JE; List, AF; Mirza, AS; Nardelli, L; Padron, E; Pinilla-Ibarz, J; Sweet, K | 1 |
| Cetkovský, P; Mayer, J; Novák, J; Pecherková, P; Petečuková, V; Ráčil, Z; Šálek, C; Schwarz, J; Vydra, J; Žák, P | 1 |
| Andreeff, M; Benton, CB; Boddu, P; Borthakur, G; Cortes, J; Daver, N; DiNardo, CD; Garcia-Manero, G; Jabbour, EJ; Kadia, T; Kanagal-Shamanna, R; Kantarjian, H; Konopleva, M; Patel, K; Ravandi, F; Takahashi, K | 1 |
| Dünweber, A; Fridthjof, KS; Friis, LS; Gørløv, JS; Kampmann, P; Kjeldsen, L; Moser, C; Møller, T; Nexø, C; Nørskov, KH; Welinder, PC | 1 |
| Chen, C; Xu, W; Yang, J | 1 |
| Aladjidi, N; Auperin, A; Couec, ML; Gandemer, V; Haouy, S; Jourdain, A; Lambliotte, A; Landman-Parker, J; Leblanc, T; Michon, J; Minard-Colin, V; Patte, C; Plat, G; Rigaud, C | 1 |
| Chen, Y; Cheng, N; Feng, Y; Lai, W; Liu, J; Zhang, L | 1 |
| Stone, RM | 1 |
| Cao, X; Cen, J; Chen, Z; Gu, W; Li, M; Liu, Y; Xiang, L; Xie, X; Zhen, X | 1 |
| Côté, S; Momparler, LF; Momparler, RL | 1 |
| Boddy, N; Burrows, F; Pallis, M; Russell, N; Seedhouse, C; Whittall, A | 1 |
| Auperin, A; Baruchel, A; Bergeron, C; Bertrand, Y; Coze, C; Lacombe, MJ; Lervat, C; Leverger, G; Méchinaud, F; Munzer, M; Nelken, B; Patte, C | 1 |
| Amadori, S; Berneman, Z; De Fabritiis, P; de Witte, T; Falzetti, F; Fazi, P; Guimaraes, JE; Halkes, CJ; Ho, AD; Karrasch, M; Latagliata, R; Lübbert, M; Magro, D; Marie, JP; Muus, P; Salih, HR; Selleslag, D; Specchia, G; Stasi, R; Suciu, S; Thomas, X; Venditti, A; Vignetti, M; Willemze, R | 1 |
| Hasegawa, D; Isoyama, K; Kajiwara, M; Kaneko, T; Kato, M; Kikuchi, A; Kinoshita, A; Koh, K; Maeda, M; Manabe, A; Ohara, A; Okimoto, Y; Saito, T; Sugita, K; Tsuchida, M | 1 |
| Anderson, CM; de Magalhaes Silverman, M; Hoffman, HT; Hoover, AC; Smith, MC; Syrbu, SI | 1 |
| Abraham, R; Barkoh, BA; Luthra, R; Medeiros, LJ; Mehrotra, M; Mishra, BM; Patel, KP; Ravandi, F; Sargent, RL | 1 |
| Brandt, M; Choi, S; Cortes, J; Faderl, S; Garcia-Manero, G; Ghanem, H; Huang, X; Jabbour, E; Kantarjian, H; O'Brien, S; Pierce, S; Ravandi, F; Verstovsek, S | 1 |
| Estey, EH; Pagel, JM; Sandhu, RK; Ueda, M; Walter, RB; Xie, H | 1 |
| Bradtke, J; Jung, R; Krumbholz, M; Metzler, M; Reinhardt, D; Stachel, D | 1 |
| Ancelet, LR; Compton, BJ; Gibbins, JD; Hermans, IF; Painter, GF; Petersen, TR; Weinkove, R | 1 |
| Chen, XC; Huang, XO; Li, JJ; Liu, T; Liu, ZG; Lu, ZP; Tang, Y | 1 |
| Kotsianidis, I; Tsatalas, C | 1 |
| Abugideiri, M; Butker, C; Butker, E; Chen, Z; Chiang, KY; Esiashvili, N; Haight, AE; Khan, MK; Kim, S; Nanda, RH; Zhang, C | 1 |
| Bosse, RC; Chaplin, DJ; Cogle, CR; Drusbosky, L; Meacham, A; Purich, DL; Siemann, DW; Walter, GA; Wasserstrom, B; Wise, E | 1 |
| Afanasyev, B; Arcese, W; Bacigalupo, A; Beelen, D; Ciceri, F; Giebel, S; Gülbas, Z; Koc, Y; Labopin, M; Mohty, M; Nagler, A; Piemontese, S; Polge, E; Rubio, MT; Santarone, S; Savani, BN; Schmid, C; Tischer, J; Wu, D | 1 |
| Brand, P; Cairo, MS; Fabricatore, S; Harrison, L; Hochberg, J; Militano, O; Morris, E; Wolownik, K | 1 |
| Braun, JT; Freter, CE; Lionberger, JM; Petruska, PJ; Ramlal, R; Schoen, MW; Woelich, SK | 1 |
| Ahn, HK; Chang, MH; Kim, SJ; Kim, WS; Lee, SJ; Yi, JH | 1 |
| Canning, C; DeAngelo, DJ; Galinsky, I; Janosova, A; Ritz, J; Soiffer, RJ; Stone, RM | 1 |
| Berlanga, JJ; Besalduch, J; Brunet, S; Bueno, J; Esteve, J; Gallardo, D; Guardia, R; Heras, I; Hoyos, M; Llorente, A; Nomdedeu, J; Pérez-García, A; Ribera, JM; Sierra, J; Tormo, M | 1 |
| Carlton, D; Edelman, MJ; Fang, HB; Gojo, I; Nakanishi, T; Ross, DD; Sausville, EA; Shiozawa, K; Tan, M; Wang, WC | 1 |
| Behrendt, CE; Gehan, EA | 1 |
| Campana, D; Crews, KR; Downing, JR; Gandhi, VV; Pounds, S; Pui, CH; Raimondi, SC; Razzouk, BI; Ribeiro, RC; Rubnitz, JE; Yang, S | 1 |
| Anensen, N; Bruserud, Ø; Bø, TH; Gjertsen, BT; Jonassen, I; Kalland, KH; Stordrange, L; Øyan, AM | 1 |
| Altman, JK; Andreeff, M; Borthakur, G; Brandwein, J; Carter, BZ; Estey, EH; Hedley, DW; Jacob, C; Jolivet, J; Karp, JE; Kassis, J; LaCasse, E; Mak, DH; Morris, SJ; Schiller, GJ; Schimmer, AD; Tallman, MS; Xu, W | 1 |
| Fathi, AT; Karp, JE | 1 |
| de Bont, ES; Kamps, WA; Koetse, HA; Rings, EH; Stellaard, F; Tissing, WJ; van Vliet, MJ | 1 |
| Chen, ZC; Li, L; Li, QB; Xia, LH; You, Y; Zou, P | 1 |
| Amadori, S; Baila, L; de Witte, T; Di Raimondo, F; Fazi, P; Ferrara, F; Labar, B; Liso, V; Mandelli, F; Marie, JP; Marmont, F; Meloni, G; Muus, P; Petti, MC; Stasi, R; Suciu, S; Thomas, X; Vignetti, M; Willemze, R; Zittoun, R | 1 |
| Agha, M; Boyiadzis, M; Foon, KA; Luong, TM; McHayleh, W; Natale, J; Raptis, A; Redner, RL; Schlesselman, JJ; Sehgal, R | 1 |
| Einsele, H; Grigoleit, GU; Kapp, M; Mielke, S; Stuhler, G; Tan, SM; Topp, MS; Unzicker, C | 1 |
| Bruserud, O; Hatfield, KJ; Kalland, KH; Kittang, AO; Oyan, AM; Reikvam, H | 1 |
| Faderl, S | 1 |
| Rowe, JM | 1 |
| Li, Y; Zhang, R; Zhang, XH | 1 |
| El-Hakam, LM; Illner, A; Ramocki, MB; Riviello, JJ | 1 |
| Arslan, M; Erkut, M; Erkut, N; Ersoz, S; Sonmez, M | 1 |
| Procházka, M; Procházka, V; Urbánek, K; Vinklerová, I | 1 |
| Ishigatsubo, Y; Kanamoari, H; Maruta, A; Tachibana, T; Takasaki, H; Tanaka, M | 1 |
| Ai, HS; Dong, Z; Guo, M; Hu, KX; Huang, YJ; Liu, GX; Qiao, JH; Qiao, JX; Sun, QY; Sun, WJ; Sun, XD; Wang, DH; Wei, L; Yu, CL | 1 |
| Andreeff, M; Carter, BZ; Coombes, KR; Kantarjian, HM; Koller, E; Kornblau, SM; Mak, DH; Qiu, YH; Ravandi, F; Thomas, DA; Zhang, N | 1 |
| Criscuolo, C; Ferrara, F; Izzo, T; Palmieri, S; Riccardi, C | 1 |
| Ashcroft, J; Moreton, P; Parrish, C | 1 |
| Alino, K; Bagain, L; Blackford, A; Briel, J; Carraway, H; Doyle, LA; Gore, SD; Greer, JM; Joseph, B; Karp, JE; Levis, MJ; Mackey, K; McDevitt, MA; Moton-Nelson, D; Resar, LS; Rudek, MA; Smith, BD; Wright, JJ; Zhao, M | 1 |
| Ding, Z; Liu, L; Wang, Z; Xu, W | 1 |
| Fujisaki, T; Moriyama, Y; Muta, T; Sawada, Y; Seike, Y; Tokuyama, T; Ueda, Y | 1 |
| Lowe, SW; Pardee, TS; Zuber, J | 1 |
| Baurmann, H; Braess, J; Buechner, T; Haferlach, C; Hahn, J; Haude, KH; Hiddemann, W; Holler, E; Kolb, HJ; Oruzio, D; Schleuning, M; Schlimok, G; Schmid, C; Schwerdtfeger, R; Spiekermann, K; Tischer, J | 1 |
| Chi, HS; Jang, S; Lee, JH; Park, BG; Park, CJ; Seo, EJ | 1 |
| Gerhard, B; Harasym, TO; Hogge, DE; Kim, HP; Mayer, LD | 1 |
| Bose, JR; Brenet, F; Curcio, TJ; Feldman, EJ; Gergis, US; Ippoliti, CM; Mayer, SA; Moh, M; Morawa, E; Ritchie, EK; Roboz, GJ; Scandura, JM; Villegas, L | 1 |
| Adjei, AA; Ames, MM; Chen, Y; Erlichman, C; Flatten, KS; Greer, J; Hogan, W; Ivy, SP; Karnitz, LM; Karp, JE; Kaufmann, SH; Litzow, MR; Loegering, DA; Maurer, MJ; Mesa, RA; Peterson, KL; Reid, JM; Schneider, PA; Smith, BD; Steensma, DP | 1 |
| Alonzo, TA; Arceci, RJ; Barnard, D; Doyle, J; Gamis, AS; Gerbing, RB; Hilden, JM; Loew, TW; Massey, G; Perentesis, J; Ravindranath, Y; Sharma, M; Smith, FO; Sorrell, AD; Taub, J | 1 |
| Shigematsu, A | 1 |
| Artz, A; Campbell, NP; Daugherty, C; Gajria, D; Godley, LA; Green, M; Gurbuxani, S; Huo, D; Hyjek, E; Larson, RA; Larson, SM; Odenike, O; Sipkins, D; Stock, W; Thirman, M; Van Besien, K; Weiner, H; Zhang, Y | 1 |
| Eyre, T; Grech, H; King, AJ; Rangarajan, D; Sampson, R | 1 |
| Atenafu, EG; Brandwein, JM; Gupta, V; Minden, MD; Murray, C; Nixon, S; Saini, L; Schimmer, AD; Schuh, AC; Yee, KW | 1 |
| Liu, X; Wan, Q; Xi, A; Zhang, C | 1 |
| Atkinson, HD; Colovic, M; Colovic, N; Jankovic, G; Kraguljac, N; Radojkovic, M; Stanisavljevic, D; Suvajdzic, N; Tomin, D; Vidovic, A | 1 |
| Chi, M; Estey, E; Lin, A; McQuary, A; Othus, M | 1 |
| Huh, J; Jung, CW; Kim, DH; Kim, H; Kim, HJ; Kim, SH; Kim, YK; Lee, WS; Min, WS; Moon, JH; Mun, YC; Park, J; Shin, MG; Sohn, SK; Won, JH | 1 |
| Zyrina, GV | 1 |
| Agresta, S; Amrein, PC; Attar, EC; Ballen, KK; Borger, DR; Burke, M; Chen, YB; Edmonds, KM; Emadi, A; Fathi, AT; Foster, J; Hill, C; Iafrate, AJ; Lopez, HU; Matulis, CR; Neuberg, DS; Sadrzadeh, H; Schenkein, DP; Stone, RM; Straley, KS; Yen, KE | 1 |
| Andreeff, M; Cragg, LH; Feldman, E; Grant, S; Kramer, L; Murgo, A; Roberts, J; Roboz, G; Tombes, MB; Winning, M | 1 |
| Wheatley, K | 1 |
| Andreeff, M; Champlin, R; Estey, E; Hu, W; Jackson, CE; Jiang, S; Konopleva, M; Reed, JC; Snell, V; Weidner, D; Zhang, X; Zhao, S | 1 |
| Gibson, AD | 1 |
| Handa, H; Isozumi, K; Komatsumoto, S; Motohashi, S; Nara, M | 1 |
| Belleri, M; Presta, M; Ribatti, D; Vacca, A | 1 |
| Aulitzky, W; Bodenstein, H; Clemens, M; Ehninger, G; Illmer, T; Neubauer, A; Repp, R; Schaich, M; Schäkel, U; Soucek, S; Wandt, H | 1 |
| Sekeres, MA; Stone, R | 1 |
| Ono, R | 1 |
| Barbui, T; Bassan, R; Buelli, M; Chiodini, B; Giussani, U; Lerede, T; Oldani, E; Rambaldi, A; Rossi, A; Viero, P | 1 |
| Andreu, R; Benlloch, L; Cervera, J; de la Rubia, J; García, I; Jarque, I; Jiménez, C; Martín, G; Martínez, J; Mollá, S; Moscardó, F; Regadera, A; Sanz, G; Sanz, M | 1 |
| Afanasiev, BV; Andreeff, M; Hu, W; Konoplev, S; Konopleva, M; Zaritskey, AY | 1 |
| Frankel, SR; Truica, CI | 1 |
| Baer, M; Becknell, B; Bloomfield, CD; Caligiuri, MA; Crawford, J; Dodge, RK; Farag, SS; Fehniger, TA; George, SL; Larson, RA; Lee, EJ; Schiffer, CA; Silverman, LR | 1 |
| Chiu, A; Kimball, AB; Kohler, S; McGuire, J | 1 |
| Tay, J | 1 |
| Balduzzi, A; Biondi, A; Bonanomi, S; Dassi, M; Gaipa, G; Perseghin, P; Rovelli, A; Uderzo, C | 1 |
| Creutzig, U; Hählen, K; Harbott, J; Huismans, DR; Kaspers, GJ; Pieters, R; Slater, RM; Veerman, AJ; Zimmermann, M; Zwaan, CM | 1 |
| Benner, A; Breitruck, J; Döhner, H; Döhner, K; Fröhling, S; Kreitmeier, S; Schlenk, RF; Tobis, K | 1 |
| Balcerzak, SP; Bloomfield, CD; Byrd, JC; Caligiuri, MA; Cataland, SR; Chan, KK; Dai, G; Farag, SF; Fisher, DB; Frankel, SR; Grever, MR; Klisovic, MI; Kourlas, PJ; Kraut, EH; Lin, ZP; Lucas, D; Marcucci, G; Porcu, P; Young, DC; Zwiebel, JA | 1 |
| Anderson, JE; Appelbaum, FR; Balcerzak, SP; Chen, IM; Head, D; Johnson, DB; Kopecky, KJ; Luthardt, FW; Norwood, TH; O'Donnell, MR; Willman, CL | 1 |
| Arthur, DC; Bloomfield, CD; Byrd, JC; Carroll, AJ; Davey, FR; Dodge, RK; Edwards, CG; Feldman, EJ; Koduru, PR; Larson, RA; Mayer, RJ; Moore, JO; Mrózek, K; Patil, SR; Pettenati, MJ; Rao, KW; Schiffer, CA; Stone, RM; Watson, MS | 1 |
| Barge, RM; Honders, MW; Veuger, MJ; Willemze, R | 1 |
| Aledo, A; Alonzo, TA; Buxton, AB; Kobrinsky, NL; Lange, BJ; Woods, WG | 1 |
| Borker, A; Ode, D; Yu, L | 1 |
| Alvarez, R; Beran, M; Cortes, J; Estey, E; Giles, FJ; Kantarjian, H; Thomas, D; Tsimberidou, AM | 1 |
| Ravindranath, Y | 1 |
| Alonzo, TA; Arceci, RJ; Bernstein, ID; Gerbing, RB; Lange, BJ; Loken, MR; Sievers, EL; Smith, FO; Woods, WG | 1 |
| Appelbaum, FR; Banker, DE; Li, HY; Willman, CL; Zager, RA | 1 |
| Black, JH; Frankel, AE; Hogge, DE; McCubrey, JA; Ramage, J; Willingham, MC | 1 |
| Björkholm, M; Brinch, L; Evensen, S; Gruber, A; Gustavsson, B; Hedenus, M; Juliusson, G; Liliemark, J; Löfvenberg, E; Nesthus, I; Paul, C; Simonsson, B; Sjo, M; Stenke, L; Tangen, JM; Tidefelt, U; Udén, AM | 1 |
| Elhamri, M; Le, QH; Tavernier, E; Thomas, X | 1 |
| Henderson, RD; Nicol, AJ; Rajah, T; Read, SJ | 1 |
| Estey, EH; Thall, PF | 1 |
| Adamczyk-Cioch, M; Dmoszynska, A; Holowiecki, J; Jamroziak, K; Konopka, L; Kuliczkowski, K; Maj, S; Marianska, B; Mazur, G; Robak, T; Wierzbowska, A; Wrzesien-Kus, A; Zawilska, K | 1 |
| Ali, R; Kimya, Y; Ozan, U; Ozçelik, T; Ozkalemkaş, F; Ozkocaman, V; Tunali, A | 1 |
| Baer, MR; Barcos, M; Blumenson, L; Ferrone, S; Ford, LA; McElwain, BK; Mortazavi, A; Slack, JL; Stewart, CC; Wetzler, M | 1 |
| Robak, T | 1 |
| Boehrer, S; Chow, KU; Hoelzer, D; Knau, A; Mitrou, PS; Napieralski, S; Nowak, D; Weidmann, E | 1 |
| Bagg, A; Carroll, M; Scialla, TJ; Simpson, SE; Xu, Q | 1 |
| Pandit, SR; Raheem, MA | 1 |
| Aulitzky, W; Bodenstein, H; Ehninger, G; Gramatzki, M; Helm, G; Link, H; Pascheberg, U; Repp, R; Schaekel, U; Sonnen, R; Soucek, S; Thiede, C; Wandt, H | 1 |
| Berry, DA; Cortes, JE; Estey, EH; Faderl, S; Ferrajoli, A; Garcia-Manero, G; Giles, FJ; Kantarjian, HM; O'Brien, S; Thomas, DA; Verstovsek, S; Wathen, JK; Xiao, LC | 1 |
| Burnett, AK; Chang, J; Chopra, R; Ewing, JC; Kell, WJ; Morgenstern, GR; Robertson, JD; Ryder, D; Scarffe, JH | 1 |
| Allen, SL; Archer, KJ; Baldus, CD; Bloomfield, CD; Caligiuri, MA; Carroll, AJ; de la Chapelle, A; Kolitz, JE; Larson, RA; Marcucci, G; Moore, JO; Powell, BL; Ruppert, AS; Tanner, SM; Vardiman, JW; Whitman, SP | 1 |
| Amadori, S; Anak, O; Aul, C; Beeldens, F; Belhabri, A; de Witte, T; Ferrant, A; Hess, U; Jehn, U; Labar, B; Mandelli, F; Muus, P; Oosterveld, M; Selleslag, D; Suciu, S; Verhoef, G; Wijermans, P; Willemze, R; Zittoun, R | 1 |
| Davis, J; Estey, E; Kantarjian, H; Koller, C; O'Brien, S; Shen, Y; Thomas, MB; Yang, Y | 1 |
| He, XY; Kalaycio, M; Lichtin, A; Pohlman, B; Rybicki, L | 1 |
| Baker, RJ; Foroni, L; Ganeshaguru, K; Jones, DT; Mehta, AB; Mitchell, WA; Prentice, HG; Wickremasinghe, RG | 1 |
| Jaffrey, I; Pashaei, S; Ryder, J; Sun, T | 1 |
| Ishigatsubo, Y; Kanamori, H; Sakai, R; Takabayashi, M | 1 |
| Cros, E; Dumontet, C; El Jafaari, A; Galmarini, CM; Graham, K; Jordheim, L; Mackey, JR; Thomas, X | 1 |
| Abrahamsson, J; Clausen, N; Forestier, E; Gustafsson, G; Hasle, H; Hovi, L; Jonmundsson, G; Lie, SO; Mellander, L | 1 |
| Bron, AJ; Lochhead, J; Salmon, JF | 1 |
| Albitar, M; Cortes, J; Estey, E; Faderl, S; Garcia-Manero, G; Giles, FJ; Kantarjian, H; Thomas, D; Tsimberidou, A; Verstovsek, S | 1 |
| Benner, A; del Valle, F; Döhner, H; Döhner, K; Fischer, JT; Fröhling, S; Grimminger, W; Gunzer, U; Haas, R; Hartmann, F; Hensel, M; Pezzutto, A; Pralle, H; Preiss, J; Schlenk, RF; Weber, C; Weber, W | 1 |
| Huang, XJ; Lu, DP; Lu, J | 1 |
| Bramwell, V; Crump, M; Levine, M; Pritchard, K; Shepherd, L; Tu, D | 1 |
| Asou, N; Horikawa, K; Koh, Y; Matsuno, F; Mitsuya, H; Nakamura, M; Tajiri, T; Tatetsu, H; Yonemura, Y | 1 |
| Burnett, AK; Chopra, R; Clark, RE; Culligan, D; Hunter, A; Kell, WJ; Milligan, DW; Prentice, AG; Rohatiner, A; Yin, JA | 1 |
| Ito, Y; Katagiri, T; Nakajima, A; Ohyashiki, K; Shimamoto, T | 1 |
| Chng, WJ | 1 |
| Bernell, P; Björkholm, M; Celsing, F; Dahl, IM; Dybedal, I; Gahrton, G; Hast, R; Hellström-Lindberg, E; Lerner, R; Lindberg, G; Linder, O; Löfvenberg, E; Nilsson-Ehle, H; Oberg, G; Ohm, L; Paul, C; Samuelsson, J; Tangen, JM; Tidefelt, U; Turesson, I; Wahlin, A; Wallvik, J; Winquist, I | 1 |
| Cerny, T; Gähler, A; Hess, U; Hitz, F | 1 |
| Okamoto, Y; Pui, CH; Razzouk, BI; Ribeiro, RC; Shenep, JL; Srivastava, DK | 1 |
| Cortes, JE; Estey, E; Faderl, S; Ferrajoli, A; Garcia-Manero, G; Giles, FJ; Kantarjian, HM; Keating, MJ; O'Brien, S; Thomas, DA; Tsimberidou, AM; Verstovsek, S | 1 |
| Andretta, C; Camera, A; Ciancia, R; Della Cioppa, P; Picardi, M; Rinaldi, CR; Rossi, M; Rotoli, B; Selleri, C; Villa, MR; Volpicelli, M | 1 |
| Depil, S; Quesnel, B; Saudemont, A; Vereecque, R | 1 |
| Creutzig, U; Kaiser, J; Klingebiel, T; Lehrnbecher, T; Reinhardt, D; Varwig, D | 1 |
| Bagrintseva, K; Eichenlaub, S; Ellwart, JW; Hiddemann, W; Kohl, TM; Schnittger, S; Schwab, R; Spiekermann, K | 1 |
| Aslan, D; Cetin, M; Hiçsönmez, G; Ozyürek, E; Tuncer, AM; Unal, S; Yenicesu, I | 1 |
| Brien, B; Chang, H; Minden, MD; Patterson, B; Salma, F; Yi, QL | 1 |
| Björkholm, M; Höglund, M; Juliusson, G; Karlsson, K; Löfgren, C; Möllgård, L; Paul, C; Tidefelt, U | 1 |
| Ahlgren, T; Billström, R; Brune, M; Hedenus, M; Höglund, M; Markevärn, B; Nilsson, B; Sallerfors, B; Simonsson, B; Stockelberg, D; Wahlin, A | 1 |
| Damon, L; Demirer, T; Derigs, G; Ferrante, P; Kröger, N; Rosti, G; Wandt, H; Zander, AR | 1 |
| Graf, M; Hecht, K; Nuessler, V; Pelka-Fleischer, R; Pfister, K; Reif, S; Schmetzer, H | 1 |
| Hoffbrand, AV; Koh, M; Mehta, A; Potter, M; Prentice, HG; Rankin, P; Virchis, A | 1 |
| Alonzo, TA; Aplenc, R; Arndt, C; Barnard, D; Dinndorf, P; Feig, S; Feusner, J; Gerbing, R; Lange, BJ; Seibel, N; Smith, FO; Weiman, M | 1 |
| Ahn, HS; Choi, HS; Han, KS; Kang, HJ; Shin, HY | 1 |
| Andreeff, M; Hu, SX; Konopleva, M; Marini, FC; McQueen, T; Ruvolo, PP; Tacke, F; Xu, HJ; Zhao, S | 1 |
| Aström, M; Björkholm, M; Hast, R; Hedenius, M; Lerner, R; Liliemark, J; Löfgren, C; Nilsson, I; Paul, C; Rödjer, S; Simonsson, B; Stockelberg, D; Tidefelt, U | 1 |
| Arthur, DC; Bloomfield, CD; Byrd, JC; Carroll, AJ; Davey, FR; Edwards, CG; Koduru, PR; Larson, RA; Mayer, RJ; Moore, JO; Mrózek, K; Pettenati, MJ; Ruppert, AS; Stamberg, J | 1 |
| Altundag, K; Altundag, O; Celik, I; Kars, A; Turker, A | 1 |
| Agazzi, A; Bertolini, F; Calabrese, L; Cinieri, S; Cocquio, A; Goldhirsch, A; Laszlo, D; Martinelli, G; Pruneri, G; Rabascio, C | 1 |
| Chaoui, D; Faussat, AM; Legrand, O; Majdak, P; Marie, JP; Perrot, JY; Tang, R | 1 |
| Baer, MR; Bloomfield, CD; George, SL; Kolitz, JE; Larson, RA; Lee, EJ | 1 |
| Auvrignon, A; Baruchel, A; Couillaud, G; Dalle, JH; Gandemer, V; Lamagnere, JP; Leblanc, T; Leverger, G; Mèchinaud, F; Michel, G; Pautard, B; Perel, Y; Piguet, Ch; Schmitt, C; Vannier, JP | 1 |
| Cros, E; Dumontet, C; Galmarini, CM; Graham, K; Mackey, JR; Thomas, X | 1 |
| Boccadoro, M; Campa, E; Campana, S; Dellacasa, C; Ferrero, D; Foli, C | 1 |
| Gotoh, A; Nakajima, A; Ohyashiki, JH; Ohyashiki, K; Sashida, G; Shin-Ya, K; Sumi, M; Tauchi, T | 1 |
| Quesnel, B; Saudemont, A; Vereecque, R | 1 |
| Bergmann, L; Fischer, JT; Ganser, A; Heil, G; Hoeffken, K; Hoelzer, D; Hofmann, WK; Knuth, A; Koelbel, CB; Kolbe, K; Langer, W; Ottmann, OG; Schmoll, HJ; Westerhausen, M; Wiebe, S; Zander, C | 1 |
| Diehl, V; Hoffmann, M; Seiberlich, B; Staib, P; Tesch, H; Weihrauch, MR | 1 |
| Aschan, J; Dugas, M; Hahn, J; Hegenbart, U; Holler, E; Kolb, HJ; Ledderose, G; Niederwieser, D; Ringdén, O; Schleuning, M; Schmid, C | 1 |
| Colburn, DE; Giles, FJ; Oladovich, D; Smith, JA | 1 |
| Arthur, C; Bashford, J; Baxter, H; Bradstock, KF; Brighton, T; Cannell, P; Catalano, J; Dunlop, L; Durrant, S; Eliadis, P; Enno, A; Gill, D; Gillett, A; Joshua, D; Juneja, S; Koutts, J; Leahy, M; Lowenthal, RM; Matthews, JP; Schwarer, AP; Szer, J; Taylor, K; Young, GA | 1 |
| Blazek, B; Cerná, Z; Gajdos, P; Hak, J; Hrstková, H; Hrusák, O; Jabali, Y; Kopecná, L; Michalová, K; Procházková, D; Ptoszková, H; Sedlácek, P; Smísek, P; Starý, J; Timr, P; Tousovská, K; Vávra, V | 1 |
| Baccarani, M; Gaitani, S; Malagola, M; Martinelli, G; Piccaluga, PP; Rondoni, M; Visani, G | 1 |
| Braess, J; Fiegl, M; Hiddemann, W; Lorenz, I; Schneiderat, P; Schoch, C | 1 |
| Batlle, M; Besalduch, J; Brunet, S; Bueno, J; Carreras, E; Esteve, J; Feliu, E; Guàrdia, R; Julià, A; Llorente, A; Montserrat, E; Oriol, A; Pedro, C; Ribera, JM; Sánchez, JM; Sierra, J; Tormo, M; Vilà, JM; Vivancos, P | 1 |
| Abrahams, L; du Toit, C; McDonald, A; Novitzky, N; Thomas, V | 1 |
| Balleari, E; Ballerini, F; Balocco, M; Canepa, L; Clavio, M; Garrone, A; Gobbi, M; Michelis, GL; Miglino, M; Pierri, I; Venturino, C | 1 |
| Gaziev, D; Grafone, T; Isidori, A; Malagola, M; Martinelli, G; Ottaviani, E; Piccaluga, PP; Santini, V; Sparaventi, G; Tosi, P; Tura, S; Visani, G | 1 |
| Cros, E; Dumontet, C; Galmarini, CM; Jordheim, L | 1 |
| Chervontseva, AM; Romanov, IuA; Savchenko, VG | 1 |
| Hokland, P; Stentoft, J; Østergaard, M | 1 |
| Brown, CA; Hashem, B; Lane, JE; Lesher, JL; Marzec, T | 1 |
| Addamo, B; Benner, A; Biedermann, HG; del Valle, F; Döhner, H; Döhner, K; Fischer, JT; Fröhling, S; Glasmacher, A; Götze, K; Griesinger, F; Grimminger, W; Haas, R; Hartmann, F; Hensel, M; Kirchen, H; Koller, E; Kremers, S; Mergenthaler, HG; Pralle, H; Preiss, J; Salwender, H; Schlenk, RF; Schoch, R; Waterhouse, C | 1 |
| Beran, M; Bonate, P; Cortes, J; Du, M; Estey, E; Estrov, Z; Faderl, S; Ferrajoli, A; Gandhi, V; Garcia-Manero, G; Giles, FJ; Kantarjian, H; Keating, M; Kwari, M; O'Brien, S; Plunkett, W; Wierda, W | 1 |
| Ikarashi, Y; Imai, C; Kakihara, T; Tanaka, A; Uchiyama, M; Watanabe, A | 1 |
| Allen, SL; Bloomfield, CD; Caligiuri, MA; Dodge, RK; George, SL; Hoke, E; Hurd, DD; Kolitz, JE; Larson, RA; Moore, JO; Powell, BL; Shea, TC; Vardiman, JW; Velez-Garcia, E | 1 |
| Baer, MR; Block, AW; Bloomfield, CD; Carroll, AJ; Farag, SS; Koduru, PR; Kolitz, JE; Larson, RA; Mayer, RJ; Moore, JO; Mrózek, K; Pettenati, MJ; Powell, BL; Ruppert, AS; Schiffer, CA; Stamberg, J; Stone, RM; Vardiman, JW | 1 |
| Broekhuizen, R; Cloos, J; Creutzig, U; Fleischhack, G; Haarman, EG; Hubeek, I; Huismans, DR; Kaspers, GJ; Litvinova, E; Peters, GJ; Zwaan, CM | 1 |
| Amrein, PC; Baer, MR; Bloomfield, CD; Davey, FR; Dodge, RK; George, SL; Kolitz, JE; Larson, RA; Moore, JO; Powell, BL; Schiffer, CA | 1 |
| Benderra, Z; Chaoui, D; Faussat, AM; Legrand, O; Marie, JP; Perrot, JY; Sayada, L | 1 |
| Kalaycio, M | 1 |
| Celik, I; Cetinkaya, YS; Gonen, C; Haznedaroglu, I | 1 |
| Gale, RE; Grandage, VL; Khwaja, A; Linch, DC | 1 |
| Bai, LY; Chao, TC; Chen, PM; Teng, HW; Wang, WS | 1 |
| Cornely, O; Neurohr, K; Reiser, M; Schinköthe, T; Staib, P; Staltmeier, E | 1 |
| Naito, K; Ohnishi, K | 1 |
| Forestier, E; Frost, BM; Gustafsson, G; Hellebostad, M; Jonsson, OG; Kanerva, J; Larsson, R; Lönnerholm, G; Nygren, P; Palle, J; Schmiegelow, K | 1 |
| Brandwein, J; Chun, K; Gupta, V; Minden, M; Schuh, A; Wells, R; Yi, QL | 1 |
| Meng, XL | 1 |
| Baran, W; Dmoszyńska, A; Grosicki, S; Hellmann, A; Hołowiecki, J; Kiebiński, M; Krawczyńska, A; Kuliczkowski, K; Kyrcz-Krzemień, S; Lech-Marańda, E; Mazur, G; Pluta, A; Robak, T; Wach, M; Wawrzyniak, E; Wierzbowska, A; Wrzesień-Kuś, A | 1 |
| Billi, AM; Bortul, R; Cappellini, A; Conte, R; Grafone, T; Mantovani, I; Martelli, AM; Martinelli, G; Tabellini, G; Tazzari, PL | 1 |
| Cedrone, M; Chierichini, A; Diverio, D; Foà, R; Lo Coco, F; Mariani, G; Pasquini, L; Pelosi, E; Peschle, C; Riccioni, R; Rossini, A; Saulle, E; Testa, U; Vitale, A | 1 |
| Fonatsch, C; Gaiger, A; Jäger, U; Kainz, B; Schwarzinger, I; Sperr, WR | 1 |
| Chau, WK; Chen, CC; Gau, JP; Ho, CH; Hsu, HC; Kwang, WK; Lee, KD; Tzeng, CH; Yang, CF; Yang, MH; You, JY; Yu, YB | 1 |
| Baer, MR; Ford, LA; Greco, WR; Minderman, H; O'Loughlin, KL; Pendyala, L; Smith, PF; Sweeney, KG; Wetzler, M | 1 |
| Botton, Sd; Chelghoum, Y; Dhedin, N; Dombret, H; Dreyfus, F; Elhamri, M; Fenaux, P; Guerci, A; Le, Q; Michallet, M; Pautas, C; Pigneux, A; Raffoux, E; Reman, O; Revel, Td; Thiebaut, A; Thomas, X; Travade, P; Troncy, J; Vekhoff, A | 1 |
| Avet-Loiseau, H; Chevallier, P; Dubruille, V; Garand, R; Guillaume, T; Harousseau, JL; Juge-Morineau, N; Mahé, B; Milpied, N; Moreau, P; Roland, V; Vigouroux, S | 1 |
| Ahmed, P; Anwar, M; Hashmi, KU; Hussain, I; Iqbal, H; Khan, B; Mahmood, A; Malik, HS; Raza, S | 1 |
| Chen, FY; Hou, M; Jin, J; Li, JM; Liang, H; Qiu, XF; Qiu, ZC; Shen, Y; Shen, ZX; Song, EY; Song, YP; Wu, DP | 1 |
| Armata, J; Balcerska, A; Balwierz, W; Chybicka, A; Dluzniewska, A; Kowalczyk, J; Matysiak, M; Ochocka, M; Radwanska, U; Rokicka-Milewska, R; Sonta-Jakimczyk, D; Wachowiak, J; Wysocki, M | 1 |
| Bloomfield, CD; Carroll, AJ; Edwards, CG; Kolitz, JE; Larson, RA; Maharry, K; Marcucci, G; Mayer, RJ; Moore, JO; Mrózek, K; Pettenati, MJ; Powell, BL; Ruppert, AS; Schiffer, CA; Sterling, LJ; Vardiman, JW | 1 |
| Becton, D; Camitta, B; Carroll, A; Chang, M; Civin, C; Dahl, G; Raimondi, SC; Ravindranath, Y; Steuber, CP; Weinstein, HJ | 1 |
| Amadori, S; Beksac, M; Cermak, J; de Witte, T; Fenaux, P; Harousseau, J; Loeffler-Ragg, J; Neuwirtova, R; Nuessler, V; Solbu, G; Suciu, S; Willemze, R; Zwierzina, H | 1 |
| Lemez, P; Urbánek, V | 1 |
| Brychtova, Y; Buchtova, I; Doubek, M; Mayer, J; Palasek, I | 1 |
| Horácek, JM; Jebavý, L; Malý, J; Praus, R; Pudil, R; Strasová, A; Tichý, M; Zák, P | 1 |
| Schiffer, CA | 2 |
| Avanzini, P; Baccarani, M; Bocchia, M; Bonini, A; Candoni, A; Castelli, M; Damiani, D; de Vivo, A; Fanin, R; Fiacchini, M; Gugliotta, L; Lauria, F; Malagola, M; Martinelli, G; Mazza, P; Michielutti, A; Ottaviani, E; Piccaluga, PP; Pricolo, G; Raspadori, D; Rondoni, M; Russo, D; Testoni, N; Visani, G; Zaccaria, A; Zuffa, E | 1 |
| Danilatou, V; Kalmanti, M; Mantadakis, E; Papadhimitriou, S; Paterakis, G; Stiakaki, E | 1 |
| Berger, MS; Cheng, SC; Cortes-Franco, JE; Estey, EH; Giles, FJ; Leopold, LH | 1 |
| Hasle, H; Hokland, P; Lund, B; Nyvold, CG; Østergaard, M | 1 |
| Braess, J; Fiegl, M; Hiddemann, W; Lorenz, I; Waxenberger, K | 1 |
| Bloomfield, CD | 1 |
| Irving, I; Kennedy, GA; McCarthy, C; Perel, JM; Walker, O; Williams, B | 1 |
| Beason, K; Hughson, M; Kozlov, I; Yu, C | 1 |
| Ball, ED; Bashey, A; Carrier, E; Castro, JE; Corringham, S; Hassidim, K; Holman, P; Ihasz, A; Keese, K; Lane, TA; Liu, L; Medina, B | 1 |
| Hasz, DE; Largaespada, DA; Mao, Z; Morgan, K; Yin, B | 1 |
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| Cros, E; Dumontet, C; Galmarini, CM; Jordheim, L; Thomas, X | 1 |
| Broekhuizen, R; Cloos, J; Creutzig, U; Gibson, BE; Hubeek, I; Kaspers, GJ; Kuik, DJ; Meijerink, JP; Peters, GJ; Pieters, R; Stam, RW; van Wering, ER; Zwaan, CM | 1 |
| Barbé, G; Bertrand, Y; Bleyzac, N; Brunet, AS; Freydière, AM; Galambrun, C; Pages, MP; Ploton, C; Pondarré, C | 1 |
| Sekeres, MA | 1 |
| Beran, M; Cortes, J; Estrov, Z; Faderl, S; Ferrajoli, A; Garcia-Manero, G; Giles, FJ; Kantarjian, HM; Koller, C; Kwari, M; O'Brien, S; Ravandi, F; Verstovsek, S; Wierda, W | 1 |
| Bennett, J; Cripe, LD; Gordon, MS; Litzow, MR; Neuberg, D; O'brien, TE; Paietta, E; Rader, K; Rowe, JM; Tallman, MS | 1 |
| Apostolidis, I; Arvanitopoulou, E; Asprogeraka, T; Bakiri, M; Giannakoulas, N; Kotsianidis, I; Marinakis, T; Matsouka, P; Pagoni, M; Papaioannou, M; Skandali, A; Spanoudakis, E; Tsatalas, K; Viniou, N; Yataganas, X; Zikos, P | 1 |
| Agis, H; Böhm, A; Florian, S; Hauswirth, AW; Krauth, MT; Samorapoompichit, P; Sonneck, K; Sperr, WR; Valent, P | 1 |
| Broekhuizen, R; Creutzig, U; den Boer, ML; Gibson, BE; Hubeek, I; Janka-Schaub, GE; Kaaijk, P; Kaspers, GJ; Peters, GJ; Pieters, R; van Wering, ES; Zwaan, CM | 1 |
| Andreeff, M; Cahill, A; Cortes, J; Faderl, S; Ferrajoli, A; Garcia-Manero, G; Giles, FJ; Jeha, S; King, I; O'brien, SM; Sznol, M; Thomas, D; Verstovsek, S; Wierda, W; Yee, KW | 1 |
| Andreeff, M; Carew, JS; Huang, P; Keating, MJ; McQueen, TJ; Pelicano, H; Plunkett, W | 1 |
| Asano, S; Fukuno, K; Iseki, T; Konuma, T; Ooi, J; Takahashi, S; Tojo, A; Tomonari, A; Tsukada, N; Uchiyama, M | 1 |
| Hanada, R; Horibe, K; Kobayashi, R; Tawa, A; Tsuchida, M; Tsukimoto, I | 1 |
| Belloc, F; Lacombe, F; Pigneux, A; Praloran, V; Tabrizi, R; Vial, JP | 1 |
| Ito, M; Kamijo, A; Maruta, I; Mizuno, Y; Onishi, H; Onose, M; Saito, H; Yamada, T | 1 |
| Aung, L; Kirk, RC; Liang, S; Quah, TC; Tan, RM; Yeoh, AE | 1 |
| Dickins, RA; Kogan, SC; Largaespada, DA; Lowe, SW; Yin, B | 1 |
| Califano, C; Celentano, M; D'Amico, MR; D'Arco, AM; Ferrara, F; Mele, G; Palmieri, S; Pollio, F | 1 |
| Marcucci, G | 1 |
| Braess, J; Haferlach, T; Holdenrieder, S; Mueller, S; Nagel, D; Schalhorn, A; Seidel, D; Stieber, P | 1 |
| Aul, C; Balleisen, L; Berdel, WE; Büchner, T; Eimermacher, H; Haferlach, T; Heinecke, A; Hiddemann, W; Kern, W; Kienast, J; Lengfelder, E; Ludwig, WD; Reichle, A; Sauerland, MC; Schnittger, S; Schoch, C; Serve, HL; Staib, P; Tchinda, J; Wörmann, B | 1 |
| Abe, S; Funato, T; Harigae, H; Ishizawa, K; Kaku, M; Kameoka, J; Sasaki, T; Takahashi, S; Tomiya, Y; Yamada-Fujiwara, M; Yamamoto, J; Yokoyama, H | 1 |
| Antonioli, E; Baccini, M; Bosi, A; Gianfaldoni, G; Leoni, F; Mannelli, F | 1 |
| Hanada, R; Kigasawa, H; Kinoshita, A; Tabuchi, K; Tomizawa, D; Tsuchida, M; Tsukimoto, I | 1 |
| Asai, O; Dobashi, N; Minami, J; Ogasawara, Y; Osawa, H; Saito, T; Takahara, S; Takei, Y; Usui, N; Yamaguchi, Y; Yano, S | 1 |
| Chalmers, L; Chamberlain, M; Robb, J; Rojiani, A | 1 |
| Bonutti, A; Cossaro, M; Di Loreto, C; Intini, S; Noce, L; Pecile, P; Saro, F; Terrosu, G | 1 |
| Baran, Y; Gunduz, U; Ural, AU | 1 |
| Alexaki, P; Christakis, GB; Megalakaki, A; Perlorentzou, S; Zarkadis, IK | 1 |
| Brandalise, SR; Matsuda, EI; Nowill, AE; Oliveira, SN; Rodrigues, PC; Viana, MB; Yunes, JA | 1 |
| Aoun, M; Beguin, H; Georgala, A; Husson, M; Meuleman, N; Nolard, N; Vekemans, M | 1 |
| Hamaki, T; Harima, A; Hoshi, K; Kajiwara, K; Kodo, H; Kozai, Y; Mizusawa, M; Yamada, K | 1 |
| Adamo, F; Amadori, S; Beeldens, F; Berneman, Z; de Witte, T; Fazi, P; Fillet, G; Jehn, U; Lefrère, F; Leone, G; Mandelli, F; Marie, JP; Montanaro, M; Muus, P; Nobile, F; Ricciuti, F; Rizzoli, V; Suciu, S; Thomas, X; Willemze, R | 1 |
| Braess, J; Fiegl, M; Hiddemann, W; Juergens, M | 1 |
| Clementino, NC; Fagundes, EM; Glória, AB; Guimarães, JP; Pedroso, ER; Quintão, JS; Rocha, V; Viana, MB | 1 |
| Creutzig, U; Dworzak, M; Graf, N; Hermann, J; Lehrnbecher, T; Niemeyer, CM; Reinhardt, D; Reiter, A; Ritter, J; Stary, J; Zimmermann, M | 1 |
| Adams, JA; Liu, JA; Morris, KL | 1 |
| Li, JY; Qian, SX; Qiu, HR; Shen, RL; Wu, YJ; Zhang, JF; Zhang, SJ; Zhou, HF | 1 |
| Baek, JH; Kim, DH; Kim, HJ; Kim, JG; Kim, YK; Lee, JJ; Sohn, SK; Yang, DH | 1 |
| Berdel, WE; Bisping, G; Brandts, C; Büchner, T; Hilberg, F; Kienast, J; Kolkmeyer, A; Kulimova, E; Mesters, RM; Müller-Tidow, C; Munzert, G; Oelmann, E; Roth, GJ; Schwäble, J; Serve, H; Stefanic, M; Steffen, B | 1 |
| Gonzalez-Carrillo, ML; Jaramillo, P; Manzano, C; Morales-Toquero, A; Reyes-Núñez, V; Ruiz-Argüelles, GJ; Ruiz-Delgado, GJ | 1 |
| Ahmad, I; André, M; Bennani, J; Bron, D; Dargent, JL; Meuleman, N; Ngirabacu, MC; Ravoet, C; Ysebrant, L | 1 |
| Albitar, M; Day, A; Do, KA; Estey, E; Giles, FJ; Jilani, I; Johnson, M; Kantarjian, H; Keating, M; O'brien, S; Pierce, S; Verstovsek, S | 1 |
| Albitar, M; Borthakur, G; Cortes, J; Faderl, S; Ferrajoli, A; Giles, FJ; Kantarjian, H; Kornblau, S; Pierce, S; Ravandi, F; Thomas, D; Verstovsek, S; Wierda, W | 1 |
| Arnaud, P; Botton, Sd; Bourhis, JH; Castaigne, S; Cordonnier, C; Corront, B; de Revel, T; Dombret, H; Elhamri, M; Fenaux, P; Gardin, C; Le, QH; Michallet, M; Pautas, C; Preudhomme, C; Quesnel, B; Raffoux, E; Reman, O; Terré, C; Thomas, X | 1 |
| Abrahamsson, J; Clausen, N; Forestier, E; Gustafsson, G; Hasle, H; Heldrup, J; Hovi, L; Jonmundsson, G; Zeller, B | 1 |
| Kantarjian, HM | 1 |
| Aulitzky, W; Cortes, J; Döhner, H; Fischer, T; Heidel, F; Huber, C; Kantarjian, H; Kindler, T; Letvak, L; Rücker, FG | 1 |
| Burnett, AK; Goldstone, AH; Hills, RK; McMullin, MF; Milligan, D; Prentice, AG; Wheatley, K | 1 |
| Roboz, GJ | 1 |
| Humphreys, P; Johnston, DL; Keene, DL; Pound, CM; Udjus, K | 1 |
| Carluccio, P; Giannoccaro, M; Liso, V; Mestice, A; Pastore, D; Rizzi, R; Specchia, G; Spinosa, G | 1 |
| Dombret, H; Thomas, X | 1 |
| Ainoon, O; Cheong, SK; Fazlina, N; Hamidah, H; Hamidah, NH; Jamal, R; Maha, A; Zarina, AL; Zulkifli, SZ | 1 |
| Haferlach, C; Hiddemann, W; Schnittger, S; Weisser, M | 1 |
| Demirel, YN; Fatih, T; Mesut, A; Selim, Y; Yuksel, P | 1 |
| Jiang, YQ; Li, JY; Lu, H; Qian, SX; Shen, YF; Tian, T; Wu, HX; Xu, W; Zhang, SJ | 1 |
| Burnett, AK; Gale, RE; Hills, RK; Linch, DC; Mead, AJ; Wheatley, K | 1 |
| Amadori, S; Buccisano, F; Consalvo, MI; De Fabritiis, P; Del Poeta, G; Del Principe, MI; Fraboni, D; Maurillo, L; Mazzone, C; Neri, B; Ottaviani, L; Panetta, P; Sarlo, C; Spagnoli, A; Tamburini, A; Venditti, A | 1 |
| Arcaro, A; Doepfner, KT; Spertini, O | 1 |
| Albarello, A; Bacigalupo, A; Balleari, E; Balocco, M; Carella, AM; Catania, G; Clavio, M; Gobbi, M; Manna, A; Michelis, G; Miglino, M; Pierri, I; Sessarego, M; Van Lint, MT; Varaldo, R; Vignolo, L | 1 |
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| Freijs, A; Jonsson, N; Karlsson, MO; Kristensen, J; Larsson, R; Lindhagen, E; Nygren, P; Quartino, A | 1 |
| Genev, ED; Grudeva-Popova, JG; Lazarova, A; Mumdjiev, IN; Spasova, MI; Stoyanova, AA | 1 |
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| Jiang, B; Sun, Zq; Wang, de B; Zhao, XS | 1 |
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| Jirillo, E; Liso, V; Magno, M; Pavone, V; Specchia, G | 1 |
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| Hara, M; Kimura, I; Kitazima, K; Takahashi, I; Tokuda, M; Yorimitsu, S | 1 |
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| Azarnia, N; Booker, L; Brennan, J; Browman, G; Epstein, J; Goldberg, J; Gottlieb, A; Grunwald, H; Preisler, HD; Raza, A | 1 |
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| Beltran, G; Stuckey, WJ | 1 |
| Chen, SC; Chu, JY; Demello, D; Gale, GB; O'Connor, DM | 1 |
| Frauer, HM; Link, H; Waller, HD; Wilms, K | 1 |
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| Hattori, M; Hayashi, Y; Honda, T; Sampi, K | 1 |
| Gerecke, D; Hirschmann, WD; Kress, M | 1 |
| Lambertenghi-Deliliers, G; Maiolo, AT; Pacciarini, MA; Pogliani, E; Polli, EE | 1 |
| Azarnia, N; Brennan, J; Browman, G; Chervenick, P; Goldberg, J; Grunwald, H; Miller, K; Preisler, HD; Raza, A; Vogler, R | 1 |
| De Vassal, F; Dorval, T; Gaget, H; Goldschmidt, E; Lemaigre, G; Machover, D; Misset, JL; Rappaport, H; Ribaud, P; Schwarzenberg, L | 1 |
| Gustavsson, A; Mitelman, F; Olofsson, T; Olsson, I | 1 |
| Manoharan, A; Wegman, E | 1 |
| Bentwich, Z; Berrebi, A; Frumkin, A; Green, L; Hurwitz, N; Levin, S; Shalev, Y | 1 |
| Gustavsson, A; Olofsson, T | 1 |
| Bowman, WP; Danks, MK; Look, AT; Ochs, J; Rivera, G; Sinkule, JA | 1 |
| Preisler, HD; Raza, A | 2 |
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| Tsukagoshi, S | 1 |
| Azarnia, N; Brennan, JK; Browman, G; Goldberg, J; Gottlieb, AJ; Miller, KB; Preisler, HD; Priore, RL; Vogler, WR; Winton, EF | 1 |
| Goldberg, J; Theodorakis, ME | 1 |
| Li, ZJ | 1 |
| Hines, JD; Winkelman, MD | 1 |
| Bjornsson, T; Capizzi, RL; Cheng, E; Cheng, YC; Sahasrabudhe, D; Tan, RS; Yang, JL | 1 |
| Moriyama, Y; Sanada, M | 1 |
| Jones, SP; Sawyer, WH; Wiley, JS | 1 |
| Boyd, AW; Sullivan, JR | 1 |
| Andreeff, M; Blumenreich, MS; Chou, TC; Clarkson, BD; Vale, K; Young, CW | 1 |
| Brennan, JK; Cantin, G | 1 |
| Capizzi, RL; Cooper, MR; Hopkins, JO; Jackson, DV; Muss, HB; Poole, M; Richards, F; Spurr, CL; Stuart, JJ; White, DR | 1 |
| Capizzi, RL; Ross, DW | 1 |
| Begg, CB; Bennett, JM; Bozdech, M; Cassileth, PA; Glick, JH; Kahn, SB; Weiler, C | 1 |
| Dubovsky, DW; Jacobs, P; Wood, L | 1 |
| Lazarus, HM | 1 |
| Anderson, T; Frick, J; Hansen, RM; Ritch, PS | 1 |
| Dekker, AW; Punt, K; van Prooijen, HC | 1 |
| Cuttner, J; Dimitriu-Bona, A; Najfeld, V; Seremetis, S; Winchester, RA | 1 |
| Bishop, JF; Mathews, JD; Paton, CM; Whiteside, MG | 1 |
| Jehn, U; Wilmanns, W | 1 |
| Bloomfield, CD; Peterson, BA | 2 |
| Ballone, E; Bonanni, G; D'Antonio, D; D'Arcangelo, L; Di Bartolomeo, P; Di Girolamo, G; Di Marzio, A; Fioritoni, G; Geraci, L; Iacone, A; Lombardo, M; Natale, D; Pandoli, G; Spadano, A; Torlontano, G | 1 |
| Marinello, MJ; Pothier, L; Preisler, HD; Reese, PA | 1 |
| Braine, HG; Markman, M; Vaughan, WP | 1 |
| Browman, G; Early, AP; Marinello, MJ; Preisler, HD; Raza, A; Stein, AM; Vlahides, G | 1 |
| Behrendt, H; de Waal, F; Hählen, K; Smets, LA; Taminiau, J | 1 |
| Akiyama, Y; Ando, S; Johno, I; Kagawa, D; Nakamura, T; Sasada, M; Uchino, H; Ueda, T | 1 |
| Marie, JP; Pochat, L; Pommier, Y; Zittoun, RA | 1 |
| Castaigne, S; Daniel, MT; Degos, L; Herait, P; Tilly, H | 1 |
| Baker, MA; Deck, JH; Grossman, L; Sutton, DM | 1 |
| Aoyagi, A; Fujiwara, M; Fuse, I; Hanano, M; Hattori, A; Hirosawa, H; Kashimura, M; Kishi, K; Koike, T; Koyama, S; Miura, R; Moriyama, Y; Nagayama, R; Ohnishi, M; Sakai, C; Sanada, M; Shibata, A; Shinada, S; Takahashi, M; Takai, K; Urushiyama, M | 1 |
| Arlin, ZA; Clarkson, BD; Dellaquila, C; Flomenberg, N; Gee, TS; Kempin, SJ; Mertelsmann, R; Straus, DJ; Young, CW | 1 |
| Amadori, S; Dahl, GV; George, SL; Kalwinsky, DK; Kumar, M; Look, AT; Mason, C; Mauer, AM; Murphy, S; Novak, R; Simone, JV | 1 |
| Bhaduri, S; Heimpel, H; Hoelzer, D; Krieger, D; Kubanek, B; Kurrle, E; Vanek, E | 1 |
| Bauters, F; Goudemand, M; Huart, JJ; Jouet, JP; Jude, B; Toussaint, B | 1 |
| Bank, A; Blom, J; Bloomfield, CD; Brunner, K; Carey, RW; Cooper, MR; Ellison, RR; Falkson, G; Glidewell, OJ; Gottlieb, A; Haurani, F; Henry, P; Hoagland, HC; Holland, JF; Hutchison, JL; James, GW; Kaan, SK; Kung, F; McIntyre, OR; Nawabi, IW; Nissen, NI; Obrecht, JP; Prager, D; Preisler, HD; Rai, KR; Ramanan, SV; Silver, RT; Weinberg, V; Wiernik, P | 1 |
| Jones, SP; Paterson, AR; Sawyer, WH; Wiley, JS | 1 |
| Sharp, JC | 1 |
| Altman, AJ; Dinndorf, P; Quinn, JJ | 1 |
| Boiron, M; Gisselbrecht, C; Jacquillat, C; Marty, M; Weil, M | 1 |
| Doi, S; Ha, K; Ikeda, T; Tawa, A; Yabuuchi, H; Yumura, K | 1 |
| Dabich, L | 1 |
| Dubovsky, DW; Jacobs, P; Kernoff, LM | 1 |
| Krieger, O; Lutz, D; Nowotny, H; Waldner, R | 1 |
| Avilés-Miranda, A; Conte-Lanza, G; Monroy-Arellano, LM; Morales-Polanco, MR; Pizzuto-Chávez, J | 1 |
| Cheever, MA; Farewell, VT; Fefer, A; Glucksberg, H; Sale, GE; Thomas, ED | 1 |
| Goldberg, J; Gottlieb, AJ; Kirshner, JJ; Nelson, DA | 1 |
| Wiernik, PH | 4 |
| Bodey, GP; Bolivar, R; Fainstein, V | 1 |
| Kimura, K | 2 |
| Andreeff, M; Büchner, T; Clarkson, BD; Hiddemann, W; Melamed, MR | 1 |
| Bottomley, SS; Hussein, KK; Livingston, RB; Salem, Z | 1 |
| McFarland, HR | 1 |
| Amare, M; Goodwin, JW; Maloney, TR; Morrison, FS; Park, CH | 1 |
| Appelbaum, FR; Cheever, MA; Fefer, A; Greenberg, PD; Kaplan, HG; Wood, T | 1 |
| Bodey, GP; Freireich, EJ; Gehan, EA; Keating, MJ; McCredie, KB; Smith, TL | 1 |
| Freireich, EJ; Gehan, EA; Keating, MJ; Smith, TL | 1 |
| Curtis, JE | 1 |
| Clarkson, BD; Gee, TS; Mertelsmann, R; Miké, V; Passe, S | 1 |
| Armitage, JO; Aunan, SB; Burns, CP; Dick, FR; Slymen, DJ | 1 |
| Ascari, E; Berzuini, C; Cresci, R; Mazzini, G; Montecucco, C; Riccardi, A; Traversi, E | 1 |
| Burke, PJ; Karp, JE; Sanford, PL; Vaughan, WP | 1 |
| Amare, M; Morrison, FS; Oishi, N; Pendleton, O; Saiki, JH; Schreiter, SL; Stuckey, WJ; Vial, R | 1 |
| Amare, M; Balcerzak, S; Benjamin, R; Costanzi, JJ; Hussein, K; Morrison, FS; Pendleton, OJ; Ryan, DH | 1 |
| Abe, M; Aiba, K; Chinen, T; Ezaki, K; Horikoshi, N; Ichiba, K; Inagaki, J; Inoue, K; Kobayashi, T; Kuraishi, Y; Meguro, S; Nagata, T; Ogawa, M | 1 |
| Andersson, B; Björkholm, M; Engstedt, L; Gahrton, G; Hast, R; Holm, G; Killander, A; Lantz, B; Lockner, D; Lönnqvist, B; Mellstedt, H; Oberg, G; Palmblad, J; Paul, C; Peterson, C; Simonsson, B; Stalfelt, AM; Udén, AM; Wadman, B | 1 |
| Dekker, AW; Punt, K; Sixma, JJ | 1 |
| Fujiwara, M; Hirosawa, H; Kishi, K; Koyama, S; Moriyama, Y; Sakai, C; Sanada, M; Shibata, A; Takahashi, M; Takai, K; Urushiyama, M | 1 |
| Bateman, JR; Lewis, JP; Linman, JW; Pajak, TF | 1 |
| Cassileth, PA; Kahn, SB; Silber, R; Weiler, C | 1 |
| Fontebuoni, A; Izzi, T; Lucarelli, G | 1 |
| Büchner, T; Hiddemann, W; Kamanabroo, D; Schulte, H; Urbanitz, D; van de Loo, J | 1 |
| Andreeva, LS; Leshchinskaia, EV; Martynenko, IN; Nikulina, VG; Ravkina, LI | 1 |
| Schmähl, D; Zeller, WJ | 2 |
| Bloomfield, CD; Hasbrouck, DJ; Hurd, DD; Peterson, BA | 1 |
| Oguro, M; Sueyama, H; Takagi, T | 1 |
| Maekawa, T; Omine, M; Tsuchiya, J | 1 |
| Kato, Y; Suzuki, H; Yamada, K | 1 |
| Fujii, S; Hiroshige, Y; Ishida, Y; Kaku, K; Matsumoto, N; Miwa, S; Nakashima, K; Shinohara, K; Yaga, K | 1 |
| Ezaki, K; Kato, Y; Kawashima, K; Kobayashi, M; Kodera, Y; Minami, S; Morishima, Y; Morishita, T; Nishiwaki, H; Ogura, M; Ohara, K; Ohno, R; Suzuki, H; Takeyama, H; Tanimoto, M; Watanabe, E; Yamada, H; Yamada, K; Yamaguchi, H; Yokomaku, S; Yoshikawa, S | 1 |
| Bloomfield, CD; Bosl, GJ; Gibbs, G; Malloy, M; Peterson, BA | 1 |
| Matthews, JH; Wood, JK | 1 |
| Hattori, KI; Kobayashi, S; Mitamura, E; Nakamura, S; Ohtake, S; Tanimoto, K; Yoshida, T | 1 |
| Cherepanova, VV; Gliasova, GA; Isaev, VG; Kaporskaia, TS; Kulikov, SM; Medvedeva, NV; Parovichnikova, EN; Rekhtman, GB; Savchenko, VG; Tikhonova, LIu | 1 |
| Baer, MR; Bloomfield, CD; Brunetto, VL; Christiansen, NP; Frankel, SR; Herzig, GP; Mrózek, K | 1 |
| Abe, T; Fujii, H; Kuzuyama, Y; Nakagawa, H; Sakabe, H; Sonoda, Y | 1 |
| Escudier, SM; Seymour, JF | 1 |
| Fukuda, R; Ichikawa, Y; Kawada, H; Kobayashi, N; Nagao, T; Yonekura, S | 1 |
| Wood, MJ | 1 |
| Ikebuchi, K; Irie, S; Matsudaira, T; Matsuishi, E; Okamoto, SI; Shimane, M; Shirafuji, N; Takahashi, S; Tani, K; Tsuruta, T | 1 |
| Carrara, P; Cenacchi, A; Clavio, M; Gamberi, B; Manfroi, S; Ottaviani, E; Testoni, N; Tosi, P; Visani, G; Zinzani, PL | 1 |
| Böckmann, A; Büchner, T; Hiddemann, W; Reuter, C; Schleyer, E; Wörmann, B; Zühlsdorf, M | 1 |
| Andrews, R; Begent, RH; Boshoff, C; Holden, L; Newlands, ES; Oliver, RT; Ong, J; Rustin, GJ; Skelton, M | 1 |
| Feldmann, L; Guerci, A; Guerci, O; Marchal, S; Merlin, JL; Missoum, N; Rose, C; Witz, F | 1 |
| Davison, G; Jacobs, P; Kelly, S; McLellan, G; Pillay, Y | 1 |
| Löwenberg, B; Nooter, K; Sonneveld, P; te Boekhorst, PA; van Kapel, J | 1 |
| Pallister, CJ; Singer, CR; Smith, JG; Smith, MA | 1 |
| Hu, ZB; McCulloch, EA; Minden, MD | 1 |
| Behm, FG; Boyett, JM; Hancock, ML; Krance, RA; Mahmoud, HH; Pui, CH; Raimondi, SC; Relling, MV; Ribeiro, RC; Sandlund, JT | 1 |
| Creutzig, U; Harbott, J; Löffler, H; Ludwig, WD; Riehm, H; Ritter, J; Schellong, G; Sperling, C; Zimmermann, M | 1 |
| Appelbaum, FR; Buckner, CD; Chauncey, T; Demirer, T; Lilleby, K; Petersen, FB; Rowley, S; Sanders, J; Storb, R; Weaver, CH | 1 |
| Chiu, JK; Dorfman, SR; Murray, JC; Ogden, AK | 1 |
| Estey, E; Freireich, EJ; Kantarjian, H; Keating, M; Marlton, P; O'Brien, S; Pierce, S | 1 |
| Andersen, JW; Bennett, JM; Cassileth, PA; Hayes, FA; Mazza, JJ; Oette, D; Paietta, E; Rowe, JM; Stadtmauer, EA; Wiernik, PH | 1 |
| Fuchigami, K; Izumikawa, K; Kohno, T; Kuriyama, K; Maeda, T; Mori, H; Nagai, K; Nakamura, H; Tomonaga, M | 1 |
| Capizzi, RL; Fleming, RA; Oliver, LK; Omura, GA; Peterson, BA; Rosner, GL; Schiffer, CA; Silver, RT; Smith, SJ; Weiss, RB | 1 |
| Aster, JC; Inhorn, RC; Roach, SA; Slapak, CA; Soiffer, R; Stone, RM; Tantravahi, R | 1 |
| Asou, N; Fujimoto, K; Hiraoka, A; Kobayashi, T; Kuriyama, K; Ohno, R; Saito, H; Tanimoto, M; Teshima, H; Yoshida, M | 1 |
| Johnson, PR; Liu Yin, JA | 1 |
| Honders, MW; Kester, MG; Landegent, JE; Stegmann, AP; Willemze, R | 1 |
| McCulloch, EA; Minden, MD; Yang, GS | 1 |
| Clausen, N; Ellegaard, J; Hokland, P; Langkjer, ST; Nørgaard, JM; Palshof, T | 1 |
| Arana, JI; Arrizabalaga, JI; Barrenetxea, JI; García, JC; Montes, PM; Rumoroso, JR | 1 |
| Jedlicková, A; Jelínek, J; Lemez, P; Lukásová, M; Palecek, A; Sajdová, J; Vítek, A; Vorlová, Z | 1 |
| Lemez, P | 1 |
| Bolaños, F; Candelaria, M; Hurtado, R; Labardini, JR; Majluf, A; Vargas, F | 1 |
| Copplestone, JA; Morgenstern, GR; Norfolk, DR; Williamson, LM; Williamson, P; Wimperis, JZ | 1 |
| Archimbaud, E; Cordonnier, C; Dreyfus, F; Fenaux, P; Jaubert, J; Leblond, V; Michallet, M; Thomas, X; Travade, P; Troussard, X | 1 |
| Büchner, T; Hiddemann, W; Reuter, C; Wörmann, B; Zühlsdorf, M | 1 |
| Cepelák, V; Cetkovský, P; Koza, V; Vít, L | 1 |
| Atkins, CD | 1 |
| Cetkovský, P; Koza, V | 1 |
| Mehta, J; Philpott, N; Powles, R; Treleaven, J | 1 |
| Champlin, R; Gajewski, J; Ho, W; Lee, M; Schiller, G; Territo, M | 1 |
| Aul, C; Bartram, CR; Heyll, A; Hildebrandt, B; Ludwig, WD; Meckenstock, G; Runde, V; Schneider, EM; Schneider, W | 1 |
| Cianfriglia, M; Eisterer, W; Gotwald, M; Hilbe, W; Hofmann, J; Ludescher, C; Thaler, J; Zabernigg, A | 1 |
| Bhalla, K; Bullock, G; Huang, Y; Ibrado, AM; Mahoney, ME; Ponnathpur, VS; Ray, S; Tang, C | 1 |
| Cassileth, PA; Friedenberg, WR; Hocking, WG; Marx, JJ; Mazza, JJ; Mercier, RJ; Miller, HJ; Raich, PC; Reding, DJ; Schloesser, LL | 1 |
| Götzl, M; Gsur, A; Kyrle, PA; Lechner, K; Pirker, R; Zöchbauer, S | 1 |
| Berdel, WE; Vogler, WR | 1 |
| Jack, FR; Summerfield, GP | 1 |
| Conley, NS; Doughney, KB; Durkin, WJ; Favis, GR; Siddiqui, T; Smith, AE; Weiss, R | 1 |
| Abgrall, JF; Flesch, M; Genne, P; Maloisel, F; Moreau, P; Pignon, B; Quiquandon, I; Saddoun, A; Solary, E; Witz, F | 1 |
| Cherepanova, VV; Isaev, VG; Kaporskaia, TS; Kliasova, GA; Kulikov, SM; Medvedeva, NV; Parovichnikova, EN; Rekhtman, GB; Savchenko, VG; Tikhonova, LIu | 1 |
| Aul, C; Burk, M; Gogolin, F; Heyll, A; Meckenstock, G; Runde, V; Söhngen, D; Winkelmann, M; Wolf, HH; Zahner, J | 1 |
| Belloc, F; Bernard, P; Boisseau, MR; Dumain, P; Lacombe, F; Makhoul, PC; Puntous, M; Reiffers, J; Saux, MC | 1 |
| Buschfort, C; Müller, MR; Rajewsky, MF; Seeber, S; Seiler, F; Thomale, J | 1 |
| Benson, E; Bishop, J; Bradstock, K; Matthews, J; Page, F | 1 |
| Belloc, F; Boiron, JM; Cony-Makhoul, P; Dubosc-Marchenay, N; Dumain, P; Fabères, C; Lacombe, F; Marit, G; Montastruc, M; Puntous, M | 1 |
| Berg, DT; Davis, RB; Frei, E; Mayer, RJ; McIntyre, OR; Moore, JO; Omura, GA; Powell, BL; Schiffer, CA; Schulman, P | 1 |
| Bishop, JF | 2 |
| Bozeman, P; Hurwitz, C; Jenkins, J; Katz, J; Krance, R; Laver, J; Mahmoud, H; Mirro, J; Shearer, P | 1 |
| Cork, A; Jeha, S; Lockhart, S; Pinkel, D; Plunkett, W; Ramirez, I; Zipf, T | 1 |
| Benz, G; Gmür, J; Gubler, J | 1 |
| Damon, LE; Linker, CA; Ries, CA; Rugo, HS | 1 |
| Hashimoto, Y; Kanamori, H; Kitamura, H; Koike, T; Matsuzaki, M; Mohri, H; Motomura, S; Ohkubo, T; Tanabe, J | 1 |
| Amaki, I; Kawashima, K; Kimura, K; Maekawa, T; Masaoka, T; Nagura, E; Ohta, K; Takaku, F; Uchino, H; Yamada, K | 1 |
| Forsblom, AM; Gahrton, G; Hellström-Lindberg, E; Kock, Y; Lindberg, G; Ost, A; Robèrt, KH | 1 |
| Akashi, K; Eto, T; Harada, M; Harada, N; Inaba, S; Niho, Y; Okamura, T; Takamatsu, Y; Teshima, T | 1 |
| Kliasova, GA | 1 |
| Perilov, AA; Poddubnaia, IV | 1 |
| Ohno, R | 1 |
| Almqvist, A; Hallman, H; Honkanen, T; Järvenpää, E; Järventie, G; Koistinen, P; Koivunen, E; Lahtinen, R; Lehtinen, M; Ruutu, T | 1 |
| Dardenne, M; de Witte, T; Delmer, A; Gerhartz, HH; Jacobs, A; Marcus, R; Solbu, G; Suciu, S; Visani, G; Zwierzina, H | 1 |
| Annaloro, C; Cofrancesco, E; Cortelezzi, A; Cortellaro, M; Della Volpe, A; Lambertenghi Deliliers, G; Mozzana, R; Oriani, A; Pozzoli, E; Soligo, D | 1 |
| Del Valle, F; Döhner, H; Ehrhardt, R; Fischer, JT; Haas, R; Ho, AD; Huberts, H; Hunstein, W; Kaplan, E; Witt, B | 1 |
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| Lister, A; Meuth, M; Phear, G; Rohatiner, A; Smith, T; Whelan, J | 1 |
| Chan, JC; Chan, JK; Lam, SY; Wong, KF | 1 |
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| Darbyshire, PJ; Mann, JR; Sartori, PC; Stevens, MC; Taylor, MH | 1 |
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| Buckley, JD; Hammond, GD; Lampkin, BC; Lee, JW; Nesbit, ME; Versteeg, C; Wells, RJ; Woods, WG | 1 |
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| Dann, EJ; Gillis, S; Rund, D | 1 |
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| Braess, J; Hiddemann, W; Kaufmann, CC; Kern, W; Kühn, S; Rührs, H; Schleyer, E; Sträubel, G; Unterhalt, M | 1 |
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| Camitta, B; Carroll, A; Chang, MN; Graham-Pole, J; Inoue, S; Krischer, J; Ravindranath, Y; Steuber, CP; Weinstein, HJ; Yeager, AM | 1 |
| Bishop, JF; Bradstock, K; Cobcroft, R; Enno, A; Fox, R; Garson, OM; Gillett, A; Herrmann, R; Joshua, D; Juneja, S; Lowenthal, RM; Matthews, JP; Page, F; Szer, J; Van Der Weyden, M; Wolf, MM; Young, GA | 1 |
| Byrd, JC; McBride, CE; Moses, FM; Robson, ME; Solimando, DA; Yavorski, RT | 1 |
| Bow, EJ; Clinch, JJ; Kilpatrick, MG; Rubinger, M; Schacter, BA; Shore, TB; Sutherland, JA; Williams, GJ | 1 |
| Arthur, DC; Barnard, DR; Buckley, JD; DeSwarte, J; Dusenbery, K; Gold, S; Kalousek, D; Kobrinsky, N; Lange, BJ; Lee, JW; Neudorf, S; Sanders, J; Woods, WG | 1 |
| Brandt, ML; Dorfman, SR; Dreyer, ZE; Murray, JC | 1 |
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| Huismans, DR; Klumper, E; Loonen, AH; Ossenkoppele, GJ; Pieters, R; Rottier, A; Veerman, AJ; Westra, G | 1 |
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| Belloc, F; Bernard, P; Boisseau, M; Cony-Makhoul, P; Dumain, P; Lacombe, F; Puntous, M; Reiffers, J | 1 |
| Clausen, N; Hasle, H; Jacobsen, BB; Jacobsen, N; Kerndrup, G; Ostergaard, E; Yssing, M | 1 |
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| Abruzzese, E; Amadori, S; Aronica, G; Cecconi, M; Del Poeta, G; Masi, M; Pisani, F; Stasi, R; Venditti, A | 1 |
| Doi, T; Kobayashi, D; Koike, K; Kougo, Y; Matsunaga, T; Muramatsu, H; Niitsu, Y; Sakamaki, S; Sato, T; Watanabe, N | 1 |
| Appelbaum, FR; Bensinger, WI; Buckner, CD; Chauncey, T; Demirer, T; Fefer, A; Lilleby, K; Petersen, FB; Rowley, S; Sanders, J; Storb, R | 1 |
| Dyson, PG; Juttner, CA; Roberts, MM; To, LB; Willson, K | 1 |
| Emmanoulides, C; Iastrebner, MC; Lee, M; Naeim, F; Schiller, G | 1 |
| Büchner, T; Hiddemann, W; Kern, W; Schleyer, E; Unterhalt, M | 1 |
| Belotti, D; Corneo, G; Maffè, PF; Pogliani, EM; Rivolta, GF | 1 |
| Appelbaum, FR; Balcerzak, SP; Bickers, JN; Grever, M; Head, DR; Hynes, HE; Kingsbury, LL; Kopecky, KJ; Simon, SR; Weick, JK; Welborn, JL | 1 |
| Chim, CS; Kwong, YL | 1 |
| Forman, SJ; Hinton, DR; Openshaw, H; Slatkin, NE; Stein, AS | 1 |
| Dan, K; Ogata, K; Yamada, T | 1 |
| Allford, S; Glynne, P; Hamblin, M; Horton, C; Mackay, H; Mehta, J; Powles, R; Prendiville, J; Saso, R; Singhal, S; Treleaven, J; Zomas, A | 1 |
| Archimbaud, E; Auzanneau, G; Cony-Makhoul, P; Cordonnier, C; Dombret, H; Dreyfus, F; Fenaux, P; Ffrench, M; Leblond, V; Marie, JP; Thomas, X; Tilly, H; Troussard, X | 1 |
| Attal, M; Blaise, D; Broustet, A; Cony-Makhoul, P; Corront, B; Faberes, C; Gastaut, JA; Hollard, D; Huguet, F; Laurent, G; Maraninchi, D; Marit, G; Michallet, M; Molina, L; Pris, J; Reiffers, J; Stoppa, AM | 1 |
| Capizzi, RL | 1 |
| Bonanad, S; Carral, A; de la Rubia, J; Jarque, I; Larrea, L; López, F; Martín, G; Martínez, J; Picón, I; Sanz, GF; Sanz, MA; Sempere, A; Soler, MA | 1 |
| Cortés, MA; Hermida, G; Iriondo, A; Mozota, ML; Olalla, I; Ortín, M; Richard, C; Zubizarreta, A | 1 |
| Appelbaum, FR; Banker, DE; Groudine, M; Norwood, T | 1 |
| Büchner, T; Hiddemann, W; Kern, W; Schleyer, E; Unterhalt, M; Wörmann, B | 1 |
| Lemez, P; Maresová, J | 1 |
| Boesen, AM; de Nully Brown, P; Grønbaek, K; Hansen, OP; Hippe, E; Hoffmann, T; Jensen, MK; Pedersen-Bjergaard, J; Storm, HH; Thorling, K | 1 |
| Geissler, K; Gisslinger, H; Haas, OA; Huhmann, IM; Jäger, U; Kalhs, P; Knöbl, P; Korninger, L; Lechner, K; Mannhalter, C; Mitterbauer, G; Pabinger, I; Schwarzinger, I; Watzke, HH | 1 |
| Edwards, JR; Gay, JC; Greer, JP; Hord, JD; Janco, RL; Lukens, JN; McCurley, TL; Wells, RJ; Whitlock, JA | 1 |
| Goldberg, SL; Klumpp, TR; Mangan, KF; Ming, PL; Mullaney, MT; Rao, PN; Redei, I | 1 |
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| Canpolat, C; Jeha, S; Lockhart, S; Pinkel, D; Ramirez, I; Zipf, T | 1 |
| Ahmed, T; Beer, M; Case, DC; Damon, L; Feldman, EJ; Linker, C; Ries, C; Rugo, H; Seiter, K | 1 |
| Croop, JM; Dunussi-Joannopoulos, K; Ferrara, JL; Krenger, W; Weinstein, HJ | 1 |
| Alyea, E; Anderson, K; Bartlett-Pandite, L; Fairclough, D; Fisher, D; Freedman, A; Freeman, A; Marcus, K; Mauch, P; Murray, C; Nadler, L; Ritz, J; Robertson, M; Schlossman, RL; Soiffer, RJ; Stone, R | 1 |
| Munshi, NC; Tricot, GJ | 1 |
| Belloc, F; Bernard, P; Besnard, S; Boisseau, MR; Dumain, P; Lacombe, F; Reiffers, J; Vial, JP | 1 |
| Burnett, AK; Goldstone, AH; Gray, RG; Hann, IM; Rees, JK; Stevens, RF; Wheatley, K | 1 |
| Fernández-Durán, DA; Grande, C; Revenga Arranz, F; Rodríguez Peralto, JL; Vanaclocha Sebastián, F | 1 |
| Bacchi, M; Cavalli, F; Fey, MF; Fopp, M; Gmuer, J; Gratwohl, A; Jacky, E; Schmid, L; Tichelli, A; Tobler, A; Tschopp, L; Von Fliedner, V | 1 |
| Brodsky, AL; Melero, MJ; Minissale, CJ; Sánchez Avalos, JC | 1 |
| Campbell, J; De La Serna, J; Diaz-Mediavilla, J; Francisco Tomás, J; García de Paredes, ML; Grande, C; Solano, C | 1 |
| Brinch, L; Evensen, SA; Hedenus, M; Hörnsten, P; Oberg, G; Simonsson, B; Wahlin, A | 1 |
| Albitar, M; Anderlini, P; Andersson, B; Beran, M; Champlin, R; Claxton, D; Estey, E; Gajewski, J; Giralt, S; Kantarjian, H; Keating, M; Khouri, I; Koller, C; Kornblau, S; Kørbling, M; Mehra, R; O'Brien, S; Przepiorka, D; Rondón, G; van Besien, K | 1 |
| Belch, AR; Gati, WP; Larratt, LM; Paterson, AR; Turner, AR | 1 |
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| Avramis, VI; Dinndorf, PA; Kelleher, JF; Krailo, MD; Liu-Mares, W; Mosher, RB; Reaman, GH; Sato, JK; Seibel, NL; Wiersma, S | 1 |
| Heitjan, DF | 1 |
| Auf der Landwehr, U; Büchner, T; Hiddemann, W; Jahns-Streubel, G; Reuter, C; Schleyer, E; Unterhalt, M; Wörmann, B | 1 |
| Becton, DL; Buck, SA; Huang, X; Ravindranath, Y; Stout, ML; Taub, JW; Vega, RA | 1 |
| Geisler, C; Myhre, J; Pedersen, M; Pedersen-Bjergaard, J | 1 |
| Benner, A; Döhner, H; Fischer, JT; Fischer, K; Gunzer, U; Haas, R; Hartmann, F; Pförsich, M; Pralle, H; Schlenk, RF; Weber, W | 1 |
| Archimbaud, E; Berneman, Z; Dardenne, M; Dekker, AW; Jehn, U; Löwenberg, B; Muus, P; Ossenkoppele, G; Schouten, H; Sonneveld, P; Stryckmans, P; Suciu, S; Vellenga, E; Verhoef, GE; Wijermans, P; Zittoun, R | 1 |
| Abgrall, JF; Audhuy, B; Briere, J; Cahn, JY; Caillot, D; Casassus, P; Delain, M; Desablens, B; Francois, S; Guilhot, F; Guyotat, D; Harousseau, JL; Herve, P; Hurteloup, P; Lamy, T; Lioure, B; Milpied, N; Pignon, B; Tellier, Z; Witz, F | 1 |
| Ciliberti, C; De Felice, L; Martelli, MP; Mascolo, MG; Petrucci, MT; Petti, MC; Ricciardi, MR; Tafuri, A | 1 |
| Hurwitz, CA; Krance, R; Laver, J; Mirro, J; Shearer, P; Srivastava, DK; Weinstein, HJ | 1 |
| Borg, AG; Burgess, R; Fisher, A; Grey, M; Wood, P; Yin, JA | 1 |
| Bloomfield, CD; Herzig, GP; Peterson, BA; Wolff, SN | 1 |
| Arning, M; Burk, M; Fartash, K; Heyll, A; Schneider, W; Volmer, M | 1 |
| de Nully Brown, P; Geisler, CH; Jurlander, J; Pedersen-Bjergaard, J; Victor, MA | 1 |
| Akashi, K; Eto, T; Fujisaki, T; Gondo, H; Harada, M; Harada, N; Hayashi, S; Hirota, Y; Kinukawa, N; Makino, S; Matsuishi, E; Miyamoto, T; Mizuno, S; Murakawa, M; Nagafuji, K; Niho, Y; Ohno, Y; Okamura, T; Shibuya, T; Takamatsu, Y; Takenaka, K; Taniguchi, S; Tanimoto, K; Teshima, T; Yamasaki, K | 1 |
| Cullis, JO; Czepulkowski, B; Gover, PA; Grace, R; Mijovic, A; Mufti, GJ; Pagliuca, A; Parker, JE; Rassam, SM; Samaratunga, IR | 1 |
| Bukh, A; Clausen, N; Hokland, P; Langkjer, ST; Nørgaard, JM; Palshof, T | 1 |
| Archimbaud, E; Berneman, ZN; de Cataldo, R; Dekker, AW; Fillet, G; Haak, H; Hagemeijer, A; Hayat, M; Löwenberg, B; Solbu, G; Sonneveld, P; Stryckmans, P; Suciu, S; Thyss, A; van der Lelie, J; Visani, G; Zittoun, R | 1 |
| Bishop, JF; Bradstock, K; Lowenthal, RM; Matthews, JP; Young, GA | 1 |
| Löwenberg, B; Rutten, FF; Suciu, S; Uyl-de Groot, CA; Vellenga, E; Willemze, R | 1 |
| Benet, L; Diaine, B; Mariani, R; Monpoux, F; Richelme, C; Sirvent, N | 1 |
| Ottaviani, E; Pellacani, A; Testoni, N; Tosi, P; Tura, S; Visani, G | 1 |
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| Almici, C; Caramatti, C; Carlo-Stella, C; Mangoni, L; Rizzoli, V | 1 |
| Appelbaum, FR; Balcerzak, SP; Godwin, JE; Head, DR; Hynes, HE; Kopecky, KJ; Leith, CP; Willman, CL | 1 |
| Bertone, A; Candoni, A; Grattoni, R; Russo, D; Zaja, F | 1 |
| Gray, RG; Hann, IM; Stevens, RF; Wheatley, K | 1 |
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| Chen, SH; Liang, DC; Liu, HC | 1 |
| Arthur, DC; Bloomfield, CD; Byrd, JC; Davey, FR; Lawrence, D; Pettenati, MJ; Qumsiyeh, M; Schiffer, CA; Stamberg, J; Tantravahi, R | 1 |
| Aveiro, F; Bernardo, M; Conduto, A; Costa, I; Cruz, E; Fernandes, JP; Ferreira, G; Gonçalves, AJ; Gouveia, J; Monteiro, A; Neves, A; Nunes, O; Ribeiro, P; Rodrigues, AS; Soares, VH; Sousa, AB; Sousa, M; Veiga, J | 1 |
| Appelbaum, FR; Banker, DE; Groudine, M; Norwood, T; Willman, CL | 1 |
| Ferrara, F; Latagliata, R; Magrin, S; Mele, G; Mirto, S; Montillo, M; Petti, MC; Pinto, A; Tedeschi, A; Zagonel, V | 1 |
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| Aul, C; Bartholomäus, A; Bettelheim, P; Büchner, T; Hiddemann, W; Kern, W; Ludwig, WD; Maschmeyer, G; Schönrock-Nabulsi, R; Wörmann, B | 1 |
| Alton, P; Elgie, AW; Noordhuis, P; Peters, GJ; Sargent, JM; Taylor, CG; Williamson, CJ | 1 |
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| Burke, PJ; Gore, SD; Weng, LJ | 1 |
| Ferrara, F; Mirto, S; Pinto, A; Zagonel, V | 1 |
| Hagiwara, S; Hirano, N; Miwa, A; Takezako, N; Togawa, A; Yuo, A | 1 |
| Arakawa, M; Chou, T; Emura, I; Ishiguro, T; Kakihara, T; Naito, M; Yoshizawa, H | 1 |
| An, E; Dan, K; Gomi, S; Kamikubo, K; Nomura, T; Ogata, K; Tamura, H; Yamada, T; Yokose, N | 1 |
| Baer, MR; Baumann, H; Bernstein, SH; Bloomfield, CD; Blumenson, L; Fries, KM; Herzig, GP; Slack, JL; Stewart, C; Wetzler, M | 1 |
| Catovsky, D; Killick, S; Matutes, E; Swansbury, J | 1 |
| Izumi, Y; Sawada, H; Serino, Y; Wake, A; Yamasaki, Y | 1 |
| Alessandrino, EP; Bernasconi, C; Bernasconi, P; Bonfichi, M; Brusamolino, E; Canevari, A; Castagnola, C; Castelli, G; Lazzarino, M; Pagnucco, G | 1 |
| Abbruzzese, A; Bianco, AR; Caraglia, M; De Lorenzo, S; Fabbrocini, A; Leardi, A; Musicò, M; Notaro, R; Pepe, S; Pizzi, C; Selleri, C; Tagliaferri, P | 1 |
| Arthur, DC; Berg, DT; Bloomfield, CD; Byrd, JC; Carroll, A; Davey, FR; Lawrence, D; Mayer, RJ; Patil, SR; Pettenati, MJ; Schiffer, CA; Tantravahi, R | 1 |
| Braess, J; Freund, M; Hanauske, A; Heil, G; Hiddemann, W; Kaufmann, C; Kern, W; Schleyer, E; Schüssler, M | 1 |
| Boiron, JM; Cardinaud, JP; Gbikpi-Benissan, G; Gruson, D; Guisset, O; Hilbert, G; Pigneux, A; Reiffers, J; Texier, J; Vargas, F | 1 |
| Friedenberg, WR | 1 |
| Aul, C; Büchner, T; Eimermacher, H; Grote-Metke, A; Hiddemann, W; Kerkhoff, A; Kern, W; Kubica, U; Kuse, R; Maschmeyer, G; Wörmann, B | 1 |
| Brunner, R; Filipits, M; Lechner, K; Pirker, R; Suchomel, RW; Zöchbauer, S | 1 |
| Du, M; Estey, E; Gandhi, V; Keating, MJ; Plunkett, W | 1 |
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| Burke, PJ; Cowan, K; Gore, SD; Jones, RJ; Piantadosi, S; Weng, LJ; Zilcha, M | 1 |
| De La Rubia, J; Gomis, F; González-García, Y; Jarque, I; Martín, G; Pérez-Sirvent, M; Sanz, MA; Sempere, A; Senent, L | 1 |
| Appelbaum, FR; Bennett, JM; Blume, KG; Cassileth, PA; Harrington, DP; Head, DR; Hurd, DD; Lazarus, HM; Paietta, E; Rowe, JM; Wiernik, PH; Willman, C | 1 |
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| Bennett, JM; Lee, S; Paietta, E; Rowe, JM; Sikic, BI; Tallman, MS; Wiernik, PH | 1 |
| Behringer, D; Köhler, G; Lindemann, A; Lübbert, M; Mertelsmann, R; Würthner, JU | 1 |
| Belch, AR; Chlumecky, V; Gati, WP; Larratt, LM; Mant, MJ; Paterson, AR; Turner, AR | 1 |
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| Altés, A; Brunet, S; Guardia, R; Martino, R; Sierra, J; Sureda, A | 1 |
| Andreeff, M; Beran, M; Cortes, J; Estey, EH; Freireich, E; Kantarjian, H; Keating, MJ; Pierce, S; Thall, PF | 1 |
| Chang, SC; Hung, CC; Ker, CC; Luh, KT; Sheng, WH | 1 |
| Akiyama, H; Asou, N; Jinnai, I; Kiyoi, H; Kuriyama, K; Minami, S; Miyawaki, S; Motoji, T; Nakano, Y; Naoe, T; Oh, H; Ohno, R; Omoto, E; Saito, H; Saito, K; Shimazaki, C; Ueda, R; Yokota, S | 1 |
| Alessandrino, EP; Bernasconi, C; Bernasconi, P; Bonfichi, M; Caldera, D; Colombo, A; Malcovati, L; Martinelli, G; Pagnucco, G; Salvaneschi, L | 1 |
| Braess, J; Feuring-Buske, M; Hiddemann, W; Kern, W; Riggert, J; Schleyer, E; Wegendt, C | 1 |
| Kishimoto, Y; Kuraishi, Y; Masaoka, T; Mizoguchi, H; Ogawa, M; Okabe, K; Saito, H; Sampi, K; Takemoto, Y; Tamura, K | 1 |
| Appelbaum, FR; Issa, JP; Kopecky, KJ; Li, Q; Mohan, A; Weick, JK; Willman, CL | 1 |
| Aleskog, A; Höglund, M; Kristensen, J; Larsson, R; Sundström, C | 1 |
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| Ehninger, G; Illmer, T; Neubauer, A; Nowak, R; Oelschlägel, U; Renner, U; Schaich, M; Subat, S; Ziegs, B | 1 |
| Archimbaud, E; Bordessoule, D; Cony-Makhoul, P; Cordonnier, C; de Revel, T; Delair, S; Dombret, H; Dreyfus, F; Fenaux, P; Ffrench, M; Janvier, M; Leblond, V; Marie, JP; Nicolini, F; Rousselot, P; Simon, M; Stoppa, AM; Thomas, X; Tilly, H; Troussard, X; Vekhoff, A | 1 |
| Avigdor, A; Ben-Bassat, I; Ben-Yehuda, D; Berkowicz, M; Chetrit, A; Gillis, S; Hardan, I; Lossos, I; Raanani, P; Shpilberg, O; Sofer, O | 1 |
| Ferrara, F; Leoni, F; Mele, G; Melillo, L; Mirto, S; Montillo, M; Pinto, A | 1 |
| Appelbaum, FR; Grever, MR; Head, DR; Hynes, HE; Karanes, C; Kopecky, KJ; Kraut, EH; Lichtin, A; Nand, S; Samlowski, WE; Vial, RH | 1 |
| Isaev, VG; Khoroshko, ND; Kliasova, GA; Kulikov, SM; Maslova, ER; Ol'shanskaia, IuV; Parovichnikova, EN; Pivnik, AV; Savchenko, VG; Tikhonova, LIu | 1 |
| Gherlinzoni, F; Isidori, A; Lemoli, R; Leopardi, G; Martinelli, G; Motta, M; Pastano, R; Piccaluga, P; Ricci, P; Rizzi, S; Testoni, N; Tosi, P; Tura, S; Visani, G | 1 |
| Kulkarni, S; Mehta, J; Min, T; Powles, R; Saso, R; Singhal, S; Swansbury, GJ; Treleaven, J | 1 |
| Adachi, K; Asou, N; Hatake, K; Hiraoka, A; Jinnai, I; Kageyama, S; Kanamaru, A; Kobayashi, T; Kuriyama, K; Matsuda, S; Minami, S; Miyawaki, S; Oh, H; Ohno, R; Ohtake, S; Omoto, E; Saito, K; Sakamaki, H; Shimazaki, C; Takahashi, M; Takeyama, K; Tamura, J; Tanimoto, M; Tsubaki, K; Yamada, O | 1 |
| Devereux, S; Goldstone, AH; Gregory, W; Hancock, B; Harrison, CN; Hoskin, P; Hudson, GV; Linch, DC; MacMillan, AK; Milligan, D; Newland, AC; Winfield, D | 1 |
| Karasawa, M; Kim, K; Kobayashi, S; Koiso, H; Naruse, T; Sakai, H; Tamura, J; Tomiazwa, T; Ueki, K; Yano, S | 1 |
| Dias Wickramanayake, P; Diehl, V; Franklin, J; Glasmacher, A; Neufang, A; Scheid, C; Schulz, A; Staib, P; Steinmetz, HT; Tesch, H | 1 |
| Hokland, P; Kristensen, JS; Nørgaard, JM; Olesen, G; Pedersen, B | 1 |
| Andreeff, M; Champlin, RC; Dong, J; Estey, EH; Estrov, Z; Jiang, S; Konopleva, M; Kornblau, SM; Okcu, MF; Reed, JC; Sanchez-Williams, G; Snell, VE; Xie, Z; Zhang, X; Zhao, S | 1 |
| Baer, M; Caligiuri, M; Dodge, RK; George, SL; Lee, EJ; Lemke, S; Powell, BL; Schiffer, CA; Smith, R; Szatrowski, TP | 1 |
| Braess, J; Hiddemann, W; Kern, W; Pförtner, J; Schleyer, E | 1 |
| Fujisawa, S; Harano, H; Ishigatsubo, Y; Kanamori, H; Mohri, H; Motomura, S; Tanabe, J | 1 |
| Bergmann, L; Brack, N; Brockhaus, W; Fischer, JT; Fuhr, HG; Ganser, A; Heil, G; Hoelzer, D; Höffken, K; Hofmann, W; Ittel, TH; Knuth, P; Kolbe, K; Langer, W; Seipelt, G | 1 |
| Abgrall, JF; Audhuy, B; Casassus, P; Deconinck, E; Delain, M; Desablens, B; Guilhot, F; Guyotat, D; Harousseau, JL; Hunault-Berger, M; Le Prise, PY; Lioure, B; Solary, E; Tournilhac, O; Vilque, JP; Witz, B | 1 |
| Balduzzi, A; Galli, MA; Longoni, D; Nicolini, B; Tagliabue, A; Uderzo, C | 1 |
| Brodsky, I; Case, D; Crilley, P; Damon, LE; Linker, CA; Navarro, W; Ries, CA; Rubin, A; Rugo, HS; Sayre, P; Topolsky, D; Wolfe, JL; Zamkoff, K | 1 |
| Beran, M; Cortes, J; Estey, E; Giles, F; Kantarjian, H; Keating, M; Koller, C; O'Brien, S | 1 |
| Funke, I; Kubanek, B; Platow, S; Wiesneth, M | 1 |
| Gangadharan, VP; Jayasree, K; Nayak, N; Prakash, NP | 1 |
| Ahmed, T; Baskind, P; Darzynkiewicz, Z; Feldman, EJ; Goff, H; Pozzuoli, M; Santos, S; Seiter, K; Traganos, F | 1 |
| Andreeff, M; Estrov, Z; Harris, D; Konopleva, M; López-Berestein, G; Tari, AM; Xie, Z; Zhao, S | 1 |
| Döhner, H; Döhner, K; Schlenk, RF; van der Reijden, BA | 1 |
| Januszewicz, EH; Juneja, S; Prince, HM; Seymour, C; Strickland, AH; Wolf, M | 1 |
| Akiyama, H; Asou, N; Kitamura, K; Kiyoi, H; Kuriyama, K; Kusumoto, S; Minami, S; Miyawaki, S; Motoji, T; Nakano, Y; Naoe, T; Nishimura, M; Ohno, R; Saito, H; Saito, K; Shimazaki, C; Shinagawa, K | 1 |
| Braess, J; Haferlach, T; Hiddemann, W; Jahns-Streubel, G; Kern, W; Keye, S; Schleyer, E; Schoch, C; Voss, S | 1 |
| Clowes, C; Duarte, R; Pu, QQ; Wang, X | 2 |
| Bennett, JM; Cassileth, PA; Kim, KM; Letendre, L; O'Connell, MJ; Oken, MM; Robles, C; Wiernik, PH | 1 |
| Dmoszyńska, A; Kowal, M; Lech-Marańda, E; Robak, T; Wrzesień-Kuś, A | 1 |
| Barge, RM; Honders, MW; Landegent, JE; Veuger, MJ; Willemze, R | 1 |
| Lange, B | 1 |
| Arima, N; Fukushima, T; Kanamaru, A; Kishimoto, Y; Kusumoto, GS; Motoji, T; Ohno, R; Okamoto, T; Shimazaki, C; Takahashi, M; Takemoto, Y; Takeshita, A; Tsukuda, K; Uike, N; Yorimitsu, S | 1 |
| Gáliková, J; Haas, T; Lemez, P | 1 |
| Barbier, M; Boutonnat, J; Ronot, X; Seigneurin, D | 1 |
| Bhalla, K; Nguyen, D; Perkins, C; Ramadevi, N; Wen, J; Worthington, E | 1 |
| Dohi, K; Fujimoto, S; Nakamura, S; Nakatani, K; Nishino, T; Shiiki, H | 1 |
| Beelen, DW; Brittinger, G; Flasshove, M; Kemmeries, G; Meusers, P; Noppeney, R; Roggenbuck, U; Scheulen, ME; Schütte, J; Seeber, S; Sohrab, S | 1 |
| Appelbaum, FR; Cassileth, PA; Forman, SJ; Harrington, DH; Head, DR; Kopecky, KJ; Mohamed, A; Paietta, E; Rowe, JM; Slovak, ML; Theil, KS; Willman, CL | 1 |
| Bajwa, RP; Reid, MM; Skinner, R; Wariyar, UK; Windebank, KP | 1 |
| Appelbaum, FR; Banker, DE; Cooper, JJ; Garrido, SM; Kopecky, K; Willman, CL | 1 |
| Amenomori, T; Atogami, S; Fukushima, T; Hayashibara, T; Honda, M; Ikeda, S; Jinnai, I; Kuriyama, K; Kusano, M; Matsuo, T; Miyazaki, Y; Momita, S; Nagai, K; Nonaka, H; Soda, H; Taguchi, J; Tomonaga, M; Toriya, K; Yoshida, S; Yoshida, Y | 1 |
| Cordone, I; De Cuia, R; Fenu, S; Guerrisi, V; Mandelli, F; Mauro, FR; Meloni, G; Pescarmona, E; Proia, A; Reato, G | 1 |
| Ciolli, S; Fanci, R; Leoni, F; Nozzoli, C; Rossi Ferrini , P; Santini, V | 1 |
| Brookes, J; Carey, P; Chu, P; Deane, M; Duncombe, A; Ganly, PS; Hutchinson, M; Jackson, G; Johnson, SA; Littlewood, TJ; MacKie, MJ; Marcus, R; Mehta, AB; Schey, S; Smith, A; Smith, GM; Taylor, P; Tollerfield, SM; Turner, GE; Wilson, MP | 1 |
| Büchner, T; Fonatsch, C; Haase, D; Haferlach, T; Heinecke, A; Hiddemann, W; Löffler, H; Sauerland, MC; Schlegelberger, B; Schoch, C; Staib, P | 1 |
| Ehninger, G; Illmer, T; Lisske, P; Mohr, B; Neubauer, A; Ritter, M; Schaich, M; Schäkel, U; Thiede, C | 1 |
| Kancherla, R; Nair, JS; Seiter, K; Traganos, F; Tse-Dinh, YC | 1 |
| Ahn, JH; Bahng, H; Kim, SH; Kim, WK; Lee, JH; Lee, JS; Lee, KH | 1 |
| Cheng, G; Chik, KW; Chui, CH; Lau, FY; Li, CK; Tsang, KS; Wong, R | 1 |
| Kim, S; Kim, SH; Kim, WK; Lee, JH; Lee, JS; Lee, KH; Seol, M | 1 |
| Dalton, W; Dorr, R; Greer, J; Grogan, T; Karanes, C; List, AF; Litchman, M; Moore, J; Pearce, T; Roe, D; Schiller, G; Spier, C; Weinberger, B | 1 |
| Collins, M; Dunussi-Joannopoulos, K; Lee, K; Leonard, JP; Runyon, K; Zuberek, K | 1 |
| Buckley, DA; du Vivier, AW; Hopster, D; Keane, FM; Mufti, GJ; Munn, SE | 1 |
| Chiusolo, P; Leone, G; Mazzotta, S; Mele, L; Pagano, L; Putzulu, R; Voso, MT | 1 |
| Ancín, I; Berlanga, JJ; Ferrá, C; Gallardo, D; González, JR; Grañena, A; Marín, D; Muñoz, J; Peris, J; Sarrá, J | 1 |
| Hokland, P; Langkjer, ST; Nørgaard, JM; Palshof, T; Pedersen, B | 1 |
| Büchner, T; Haferlach, T; Heinecke, A; Hiddemann, W; Sauerland, MC; Schoch, C | 1 |
| Cha, KE; Lee, KN; Yoon, SY | 1 |
| Abonour, R; Kim, K; Longo, WL; Mosher, DF; Turman, NJ; Vidarsson, B; Wiersma, SR; Williams, EC; Woodson, RD | 1 |
| Burnett, AK; Liu Yin, JA; Rees, JK; Wheatley, K | 1 |
| Bishop, JF; Bradstock, KF; Cobcroft, RG; Dodds, AJ; Enno, A; Garson, OM; Gillett, EA; Hermann, RP; Joshua, DE; Juneja, SK; Lowenthal, RM; Ma, DD; Matthews, JP; Szer, J; Taylor, KM; Wolf, M; Young, GA | 1 |
| Dumontet, C; Galmarini, CM; Mackey, JR | 1 |
| Ahmed, T; Feldman, EJ; Kancherla, R; Liu, D; Papageorgio, C; Pozzuoli, M; Seiter, K; Sreekantaiah, C; Weisberger, J; Weiss, M | 1 |
| Ariola, C; Cordone, I; Fazi, F; Fenu, S; Mandelli, F; Montefusco, E; Nanni, M; Petti, MC; Spadea, A; Spiriti, MA | 1 |
| Carella, AM; Carotenuto, M; Cascavilla, N; D'Arena, G; Greco, MM; Ladogana, S; Melillo, L; Perla, G; Sajeva, MR | 1 |
| Balleari, E; Beltrami, G; Canepa, L; Carrara, P; Cerri, R; Clavio, M; Damasio, E; Gatto, S; Ghio, R; Gobbi, M; Masoudi, B; Miglino, M; Pierri, I; Sessarego, M | 1 |
| Baccarani, M; Bertone, A; Bucalossi, A; De Vivo, A; Gobbi, M; Lauria, F; Marin, L; Mazza, P; Michelutti, A; Michieli, M; Pierri, I; Pricolo, G; Raspadori, D; Russo, D; Zaccaria, A; Zuffa, E | 1 |
| Aoudjhane, M; Chéron, N; Deloux, J; Douay, L; Elloumi, M; Fouillard, L; Gorin, NC; Guiguet, M; Isnard, F; Laporte, JP; Lesage, S; Lopez, M; Najman, A; Van Den Akker, J; Zunic, P | 1 |
| Glimelius, B; Kimby, E; Nygren, P | 1 |
| Alessandrino, EP; Bernasconi, C; Bernasconi, P; Castagnola, C; Colombo, A; Corso, A; Della Porta, M; Lazzarino, M; Lunghi, M; Mangiacavalli, S; Pagnucco, G | 1 |
| Baer, MR; Berg, DT; Bloomfield, CD; Dodge, RK; George, SL; Lee, EJ; Moore, JO; Paciucci, PA; Powell, BL; Schiffer, CA; Schulman, PP; Stone, RM | 1 |
| Braess, J; Büchner, T; Hiddemann, W; Kern, W; Ohnesorge, J; Schleyer, E; Unterhalt, M; Wittmer, E; Wörmann, B | 1 |
| Bonifazi, F; Bonini, A; Castellani, S; Gugliotta, L; Isidori, A; Lemoli, RM; Malagola, M; Martinelli, G; Motta, MR; Piccaluga, PP; Rizzi, S; Tura, S; Visani, G | 1 |
| Behm, FG; Pritchard, M; Pui, CH; Raimondi, SC; Razzouk, BI; Ribeiro, RC; Rubnitz, JE; Sandlund, JT; Srivastava, DK; Tong, X | 1 |
| Arthur, C; Bashford, J; Baxter, H; Bradstock, K; Brighton, T; Cannell, P; Dunlop, L; Durrant, S; Eliadis, P; Enno, A; Gill, D; Gillett, A; Gottlieb, D; Januszewicz, H; Joshua, D; Leahy, M; Lowenthal, R; Matthews, J; Schwarer, A; Taylor, K; Young, G | 1 |
| Fortney, JE; Gibson, LF; Wenger, SL; Zhao, W | 1 |
| Calvo, F; Cros, E; Dumontet, C; El Jafaari, A; Galmarini, CM; Graham, K; Mackey, JR; Rousselot, P; Thomas, X | 1 |
| Asano, S; Iseki, T; Ito, K; Nagayama, H; Ooi, J; Shirafuji, N; Tani, K; Tojo, A; Tomonari, A | 1 |
| Fukushima, T; Goto, N; Imamura, S; Iwasaki, H; Kawai, Y; Kishi, S; Masada, M; Tsutani, H; Ueda, T; Urasaki, Y; Yamauchi, T; Yoshida, A | 1 |
| Budman, DR; Calabro, A; Kreis, W | 1 |
| Andreesen, R; Aul, C; Balleisen, L; Berdel, W; Büchner, T; Eimermacher, H; Gassmann, W; Grüneisen, A; Haase, D; Haferlach, T; Hartlapp, J; Heinecke, A; Hiddemann, W; Hirschmann, WD; Löffler, H; Ludwig, WD; Maschmeyer, G; Pielken, HJ; Rasche, H; Reis, HE; Sauerland, MC; Schoch, C; Staib, P; Uhlig, J; Weh, HJ; Wörmann, B | 1 |
| Faber, E; Hlusí, A; Hubácek, J; Indrák, K; Jarosová, M; Jebavý, L; Kmonícek, M; Knotková, R; Krahulová, M; Malý, J; Mayer, J; Penka, M; Szotkowski, T; Voglová, J; Zapletalová, J | 1 |
| Appelbaum, FR; Banker, DE; Cooper, JJ; Cotter, FE; Fennell, DA; Willman, CL | 1 |
| Craddock, C; Garg, M; Lawler, M; Pawson, R; Potter, MN; Prentice, HG; Rassam, S; Rezvani, K; Theocharous, P; Yin, JA | 1 |
| Frewin, RJ; Johnson, SA | 1 |
| Anagnostopoulos, N; Androutsos, G; Galanopoulos, A; Kalmantis, T; Meletis, J; Paterakis, G; Rombos, Y; Sagriotis, A; Symeonidis, A; Tiniakou, M; Tsimberidou, AM; Yataganas, X; Zoumbos, N | 1 |
| Arcese, W; Cerretti, R; De Felice, L; Donato, V; Fenu, S; Guglielmi, C; Iori, A; Laurenti, L; Mengarelli, A; Micozzi, A; Romano, A; Torromeo, C | 1 |
| Barge, RM; Heemskerk, MH; Honders, MW; Veuger, MJ; Willemze, R | 1 |
| Appelbaum, FR | 1 |
| Iwakiri, R; Kumakawa, T; Mikoshiba, M; Mori, M; Ohta, M; Tsutsumi, H | 1 |
| Dan, K; Inami, M; Inokuchi, K; Miyata, J; Tajika, K; Watanabe, A; Yamaguchi, H; Yokomizo, E | 1 |
| Bendix, K; Hokland, P; Kjeldsen, E; Kristensen, JS; Meyer, K; Nørgaard, JM; Olesen, G; Olesen, LH; Pedersen, B | 1 |
| Barbui, T; Bassan, R; Borleri, G; Buelli, M; Chiodini, B; Lerede, T; Rambaldi, A; Rossi, A; Viero, P | 1 |
| Becker, PS; O'Donnell, J; Quesenberry, PJ; Rossi, HA; Sarcinelli, F; Stewart, FM | 1 |
| Autrup, H; Autrup, JL; Hokland, P; Pedersen, L | 1 |
| Gallagher, M; Garban, F; Jacob, MC; Jouvin-Marche, E; Marche, PN; Moine, A; Sotto, JJ | 1 |
| Ben-Am, M; Burnett, A; Capdeville, R; Dekker, A; Ferrant, C; Gratwohl, A; Kovacsovics, T; Löwenberg, B; Ossenkoppele, G; Pfister, C; Rosenkranz, G; Sonneveld, P; Vellenga, E; Verhoef, G; Vossebeld, P; Yin, L | 1 |
| Anglaret, B; Archimbaud, E; Belhabri, A; Chelghoum, Y; Dhedin, N; Dombret, H; Fière, D; Michallet, M; Reman, O; Thomas, X; Vekhoff, A; Wattel, E | 1 |
| Dölken, G; Fiedler, F; Hasenclever, D; Helbig, W; Herold, M; Kämpfe, D; Krahl, R; Kubel, M; Mantovani, L; Niederwieser, D; Pasold, R; Pönisch, W; Schmoll, HJ; Súbert, R | 1 |
| Annunziata, M; Annunziata, S; Copia, C; De Simone, M; Ferrara, F; Mele, G; Palmieri, S; Pocali, B; Schiavone, EM; Sebastio, L; Viola, A | 1 |
| Calvo, F; Cros, E; Dumontet, C; El Jafaari, A; Galmarini, CM; Rousselot, P; Thomas, X | 1 |
| Andresen, S; Elson, P; He, XY; Hussein, M; Kalaycio, M; Lichtin, A; Pohlman, B | 1 |
| Beksac, M; Dalva, K; Hayran, M; Ilhan, O; Koc, H; Konuk, N; Ozcan, M; Sertkaya, D; Topcuoglu, P; Ustün, C | 1 |
| Beran, M; Cortes, JE; Estey, EH; Giles, FJ; Kantarjian, HM; Pierce, SA; Thall, PF; Thomas, DA; Wang, XM | 1 |
| Calvo, F; Cros, E; Dumontet, C; El Jaffari, A; Galmarini, CM; Rabilloud, M; Rousselot, P; Thomas, X | 1 |
| Brighton, T; Kwan, YL; Manoharan, A; Trickett, A | 1 |
| Bottomley, RH; Grozea, PN; Nordquist, RE; Shaw, MT | 1 |
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| Burge, PS; Prankerd, TA; Richards, JD; Sare, M; Thompson, DS; Wright, P | 1 |
| Gürtler, R; Raderecht, C | 1 |
| Chabner, BA; Chang, P; Coleman, CN; Hande, KR; Stoller, RG | 1 |
| Higuchi, T; Nakamura, T; Sasada, M; Sawada, H; Tatsumi, K | 1 |
| Amadori, S; Fabiani, F; Grignani, F; Liso, V; Mandelli, F; Martelli, M; Neri, A; Petti, MC; Tonato, M | 1 |
| Anderson, C; Raab, MJ; Raab, SO | 1 |
| Adamson, TC; Van Slyck, EJ | 1 |
| Hasegawa, Y; Masaoka, T; Shibata, H; Takubo, T; Ueda, T | 1 |
| Leventhal, BG; Margileth, DA; Pizzo, PA; Poplack, DG | 1 |
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| Chiyoda, S; Kubota, K; Miura, Y; Mizoguchi, H; Muto, Y; Takaku, F | 1 |
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| Bateman, JR; Lewis, JP; Linman, JW; Marshall, GJ; Pajak, TF | 1 |
| Capote Armas, LF; de la Torre Fernandez, JM; Domínguez Carmona, A; Montero Vázquez, J | 1 |
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| Bottino, J; Buckles, R; Freireich, EJ; Herbst, S; Ho, DW; Lawson, M; McCredie, KB | 1 |
| Gerecke, D; Gross, R; Hirschmann, WD; Voigtmann, R | 1 |
| Amadori, S; Mandelli, F; Meloni, G; Pacilli, L; Papa, G | 1 |
| Balleisen, L; Büchner, T; Delvos, U; Hiddemann, W; Kamanabroo, D; Lagrèze, EM; Meister, R; Schmitz-Huebner, U; Schulte, H; Urbanitz, D; van de Loo, J | 1 |
| Bertino, JR; Cadman, EC; Capizzi, RL; McIntosh, S; Rudnick, SA; Skeel, RT | 1 |
| Faltermeier, MT; Hossfeld, DK; Schmidt, CG | 1 |
| Fujimoto, T; Hasegawa, K; Hiyoshi, Y; Ito, M; Kim, PY; Nose, K | 1 |
| Fukunaga, Y; Kobayshi, M; Kohgo, T; Shimizu, H; Ueda, Y; Yamamoto, M | 1 |
| Bagby, GC; Richert-Boe, KE | 1 |
| Balducci, L; Morrison, FS; Newcomb, M; Thigpen, JT | 1 |
| Anger, B; Bargon, G; Heimpel, H; Kubanek, B; Schreml, W | 1 |
| Balcerzak, SP; Bickers, J; Bodey, GP; Coltman, CA; Costanzi, JJ; Freireich, EJ; Gehan, EA; Groppe, C; Haut, A; Hewlett, JS; McCredie, KB; Smith, TL | 1 |
| Goto, M; Handa, M; Negishi, M; Nemato, K; Suzuki, H; Toyama, K; Udagawa, Y | 1 |
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| Faltermaier, MT; Hossfeld, DK; Schmidt, CG | 1 |
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| Bodey, GP; Freireich, EJ; McCredie, KB; Rodriguez, V | 1 |
| Abakumov, EM; Agafonov, VA; Frenkel', MA; Lorie, IuI; Solov'eva, EA | 1 |
| Haghbin, M; Murphy, ML; Tan, CT | 1 |
| Cassileth, PA; Katz, ME | 1 |
| Bodey, GP; Freireich, EM; McCredie, KB; Whitecar, JP | 1 |
| Bodey, GP; Burgess, MA; Freireich, EJ; McCredie, KB; Smith, TL; Whitecar, JP | 1 |
| Armitage, JO; Burns, CP | 1 |
| Bryan, JH; Morgan, SK; Pullen, J; Steuber, CP; Sutow, WW; Thomas, D; Vats, T | 1 |
| Alperin, JB; Costanzi, JJ; Gagliano, RG; Terrebonne, AM | 1 |
| Cowan, DH; Kouroupis, GM; Leers, WD | 1 |
| Bouchard, M; Bousser, J; Diaz-Mayo, C; Facquet-Danis, J; Percie-du-Sert, M; Zittoun, R | 1 |
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| Aisner, J; Fortner, C; Lichtenfeld, JL; O'Connell, MJ; Schiffer, CA; Schimpff, SC; Wiernik, PH | 1 |
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| Brandt, W; Hartwich, G; Petzoldt, R | 1 |
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| Derulska, D; Rokicka-Milewska, R | 1 |
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| Gau, JP; Hu, HT; Hwang, WL; Tsai, YT; Young, JH | 1 |
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| Dobson, AT; Feldman, LT; Margolis, TP; Sedarati, F; Stevens, JG | 1 |
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| Kosaka, M; Miyamoto, Y; Mizuguchi, T; Tamura, K | 1 |
| Davies, JM; Flanagan, NG; Gorst, DW; Johnson, PR; Lewis, MJ; Liu Yin, JA | 1 |
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| Chang, CS; Chen, TP; Lin, SF; Lin, TC; Liu, HW; Wei, SY | 1 |
| Grassi, D; Tartas, N | 1 |
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| Arlin, Z; Bhalla, K; Grant, S; Holladay, C; Ibrado, AM; Jasiok, M | 1 |
| Berg, D; Cannistra, SA; DiCarlo, J; Griffin, JD; Groshek, P; Kanakura, Y; Mayer, RJ | 1 |
| Huijgens, PC; Langenhuijsen, MM; Nauta, JJ; Ossenkoppele, GJ; Wijermans, PW | 1 |
| Boeckmann, A; Büchner, T; Freire, EA; Hiddemann, W; Innig, G; Koenigsmann, M; Ludwig, WD; Maschmeyer, G; Wörmann, B; Zühlsdorf, M | 1 |
| Baars, A; Freund, M; Giller, S; Hinrichs, F; Körfer, A; Link, H; Meran, J; Poliwoda, H | 1 |
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| Farhi, DC; Rosenthal, NS | 1 |
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| Griffiths, M | 1 |
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| Capizzi, RL; Cooper, MR; Lyerly, ES; Powell, BL | 1 |
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| Hiddemann, W; Kreutzmann, H; Maschmeyer, G; Wendt, F | 1 |
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| Dutcher, JP; Harwood, KV; Markus, S; Schiffer, CA; Weinberg, V; Wiernik, PH | 1 |
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| Abe, T; Akasaka, K; Inamoto, Y; Ishikura, H; Izumi, Y; Katoh, Y; Okada, H; Okazaki, T; Sawada, H; Usui, T | 1 |
| Kakita, T; Kubo, A; Moriguchi, T; Nakamura, T; Nishimura, T; Sasada, M; Uchino, H; Ueda, T | 1 |
| Hiyoshi, M; Kawarabayashi, K; Kishida, T; Kojima, K; Sagawa, H; Sannomiya, Y; Sasaki, A; Yamane, T; Yokomatsu, Y; Yoshikawa, T | 1 |
| Agarwal, S; Dua, H; Kochupillai, V; Kumar, L; Singh, S | 1 |
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| Hattori, M; Kaneko, Y; Sakurai, M; Sampi, K | 1 |
| Bodensteiner, J; Dunton, SF; Krous, HF; Nitschke, R; Spruce, WE | 1 |
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| Capizzi, RL; Cooper, MR; Jackson, DV; Muss, HB; Powell, BL; Rathmell, JP; Richards, F; Stuart, JJ; White, DR; White, JC | 1 |
| Iacoboni, S; Keating, MJ; Plunkett, W | 1 |
| Bishop, JF; Cobcroft, R; Dodds, A; Joshua, DE; Kronenberg, H; Lowenthal, RM; Manoharan, A; Whiteside, MG; Wolf, M | 1 |
| Camitta, BM; Casper, J; Holcenberg, JS; Kamen, BA; Lauer, S | 1 |
| Azarnia, N; Barcos, M; Browman, G; Goldberg, J; Preisler, HD; Priore, R; Rakowski, I; Raza, A; Vogler, R; Winton, EL | 1 |
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| Cheson, BD; Friedman, MA; Jasperse, DM; Simon, R | 1 |
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| Hirano, M; Ikeda, Y; Kimura, K; Kobayashi, M; Ohara, K; Ohno, R; Ohta, K; Yamada, K; Yoshikawa, H; Yoshikawa, S | 1 |
| Ahmed, T; Arlin, ZA; Baskind, P; Feldman, E; Mehta, R; Mittelman, A; Rieber, E; Sullivan, P; Weinstein, P | 1 |
| Carey, R; Davis, RB; Dupre, E; Hoagland, HC; Kirshner, J; Kopel, S; Levy, RN; Preisler, H; Richards, F; Schulman, P | 1 |
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| Borrego, D; Jarque, I; Lorenzo, I; Martín-Aragonés, G; Martínez, JA; Pastor, E; Rafecas, J; Sanz, G; Sanz, MA; Sayas, MJ | 1 |
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| Dixon, D; Estey, E; Freireich, EJ; Keating, M; McCredie, K; Plunkett, W | 1 |
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| Abenavoli, MR; Comis, M; Iacopino, P; Neri, A | 1 |
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| Nakamura, T; Uchida, M; Ueda, T | 1 |
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| Fukusima, Y; Mamiya, S; Miura, AB; Miyazaki, S; Nakayama, Y; Ohshima, A; Sato, T; Takahashi, T; Yanagisawa, M; Yoshida, K | 1 |
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| Bennett, J; Browman, G; D'Arrigo, P; Goldberg, J; Gottlieb, A; Grunwald, H; Larson, R; Preisler, HD; Raza, A; Vogler, R | 1 |
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| Azarnia, N; Barcos, M; Browman, M; D'Arrigo, P; Doeblin, T; Grunwald, H; Larson, R; Preisler, HD; Raza, A; Walker, I | 1 |
| Hirota, N; Kano, Y; Miura, Y; Ohsaka, A; Okada, K; Sakamoto, S; Sasaki, R; Takeda, K; Tsuboyama, A | 1 |
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| Castaigne, S; Daniel, MT; Degos, L; Sigaux, F; Tilly, H | 2 |
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| Arakawa, S; Esumi, N; Imashuku, S; Todo, S | 1 |
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| Flexner, JM; Herzig, GP; Herzig, RH; Lazarus, HM; Marion, J; Phillips, GL; Spitzer, TR; Stein, RS; Wolff, SN | 1 |
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| Alessandrino, EP; Bernasconi, C; Brusamolino, E; Lazzarino, M; Orlandi, E | 1 |
| Preisler, HD; Priore, RL; Rustum, Y | 1 |
| Lewis, JP; Meyers, FJ; Tanaka, L | 1 |
| Advani, SH; Ahuja, HG; Gopal, R; Kamat, DM; Nair, CN; Pai, MR; Saikia, TK | 1 |
| Ishikura, H; Izumi, Y; Mochizuki, T; Okazaki, T; Sawada, H; Tashima, M; Uchino, H; Yamagishi, M | 1 |
| Beguin, Y; Bury, J; Fillet, G; Lennes, G | 1 |
| Andersson, BS; Cogan, BM; Estey, EH; Freireich, EJ; Keating, MJ; McCredie, KB | 1 |
| Barcos, M; Preisler, HD; Raza, A | 1 |
| Ruiz-Arguelles, GJ | 1 |
| Mann, JR | 1 |
| Bailey, CC; Brown, MJ; Geary, CG; Israëls, MC; Weatherall, DJ; Whittaker, JA | 1 |
| Gottlieb, JA | 1 |
| Abbrederis, K; Schmalzl, F | 1 |
| Atkinson, K; Clink, HM; Kay, HE; McElwain, TJ; Powles, R; Wells, DG | 1 |
| Alter, HJ; Bleyer, WA; Buja, ML; Bull, JM; Bull, MI; Decter, J; Gralnick, HR; Graw, RG; Henderson, ES; Herzig, GP; Herzig, RH; Kirkpatrick, CH; Krueger, GR; Leventhal, BG; Lohrmann, HP; McGinniss, MH; Whang-Peng, J; Yankee, RA | 1 |
| Chudomel, V; Hrák, J; Libánský, J; Sedlácková, M | 1 |
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| Clarkson, B; Fried, J; Okita, T; Ota, K; Sakai, Y; Strife, A | 1 |
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| Abe, T; Adachi, Y; Furusawa, S; Kashiwagi, H; Shishido, H | 1 |
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| Bateman, CJ; Beard, ME; Crowther, D; Malpas, JS; Whitehouse, JM | 1 |
| Gunz, FW; Levi, JA; Vincent, PC | 3 |
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| Bateman, CJ; Beard, ME; Crowther, D; Fairley, GH; Gauci, CL; Malpas, JS; Powles, RL; Scott, RB; Wrigley, PF | 1 |
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77 review(s) available for cytarabine and Acute Disease
| Article | Year |
|---|---|
Post-Induction Treatment for Acute Myeloid Leukemia: Something Change?
Topics: Acute Disease; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Male; Middle Aged; Neoplasm, Residual; Remission Induction; Survival Analysis; Transplantation, Homologous | 2021 |
New agents in acute myeloid leukemia: beyond cytarabine and anthracyclines.
Topics: Acute Disease; Anthracyclines; Antineoplastic Agents; Apoptosis; Cell Cycle; Cytarabine; Flavonoids; Humans; Leukemia, Myeloid; Piperidines | 2009 |
Optimal induction and post-remission therapy for AML in first remission.
Topics: Acute Disease; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Graft vs Leukemia Effect; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Living Donors; Middle Aged; Multicenter Studies as Topic; Prospective Studies; Randomized Controlled Trials as Topic; Remission Induction; Survival Rate; Young Adult | 2009 |
Granulocytic sarcoma of abdomen in acute myeloid leukemia patient with inv(16) and t(6;17) abnormal chromosome: case report and review of literature.
Topics: Abdominal Neoplasms; Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Chromosome Inversion; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 17; Chromosomes, Human, Pair 6; Cytarabine; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Remission Induction; Sarcoma, Myeloid; Translocation, Genetic | 2010 |
[Significance of intensified conditioning regimen for allogeneic hematopoietic stem cell transplantation for treatment of acute leukemias].
Topics: Acute Disease; Cyclophosphamide; Cytarabine; Etoposide; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Melphalan; Recurrence; Risk; Transplantation Conditioning; Transplantation, Homologous; Whole-Body Irradiation | 2011 |
Older adults with acute myeloid leukemia.
Topics: Acute Disease; Age Factors; Aged; Aging; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Cytarabine; Drug Tolerance; Growth Substances; Humans; Leukemia, Myeloid; Recurrence; Remission Induction | 2002 |
Acute rhabdomyolysis as a complication of cytarabine chemotherapy for acute myeloid leukemia: case report and review of literature.
Topics: Acute Disease; Acute Kidney Injury; Apoptosis; Cytarabine; Humans; Leukemia, Myelomonocytic, Acute; Male; Middle Aged; Pancreatitis; Respiratory Insufficiency; Rhabdomyolysis; Treatment Outcome | 2002 |
Recent advances in pediatric acute lymphoblastic and myeloid leukemia.
Topics: Acute Disease; Antineoplastic Agents; Biomarkers, Tumor; Child; Chromosome Aberrations; Clinical Trials as Topic; Cytarabine; Disease-Free Survival; Humans; Leukemia, Myeloid; Mitoxantrone; Neoplasm, Residual; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2003 |
Purine nucleoside analogues in the treatment of myleoid leukemias.
Topics: Acute Disease; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cladribine; Clinical Trials as Topic; Cytarabine; Drug Synergism; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Humans; Infant; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Male; Middle Aged; Pentostatin; Peripheral Blood Stem Cell Transplantation; Remission Induction; Salvage Therapy; Transplantation Conditioning; Transplantation, Autologous; Transplantation, Homologous; Treatment Outcome; Vidarabine | 2003 |
Viridans streptococcal sepsis: clinical features and complications in childhood acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Chromosome Aberrations; Combined Modality Therapy; Cytarabine; Daunorubicin; Deoxyadenosines; Double-Blind Method; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Hypotension; Immunocompromised Host; Leukemia, Myeloid; Male; Mycoses; Neutropenia; Randomized Controlled Trials as Topic; Respiratory Distress Syndrome; Retrospective Studies; Sepsis; Streptococcal Infections; Viridans Streptococci | 2003 |
Secondary acute leukemia following mitoxantrone-based high-dose chemotherapy for primary breast cancer patients.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Epirubicin; Female; Humans; Incidence; Leukemia, Myeloid; Leukemia, Myelomonocytic, Acute; Leukemia, Promyelocytic, Acute; Leukemia, Radiation-Induced; Lymphatic Metastasis; Melphalan; Middle Aged; Mitoxantrone; Neoplasms, Second Primary; Paclitaxel; Peripheral Blood Stem Cell Transplantation; Radiotherapy, Adjuvant; Thiotepa; Transplantation Conditioning; Transplantation, Autologous | 2003 |
Problems related to resistance to cytarabine in acute myeloid leukemia.
Topics: Acute Disease; Antimetabolites, Antineoplastic; Cytarabine; Drug Resistance, Neoplasm; Enzyme Inhibitors; Humans; Leukemia, Myeloid; Ribonucleotide Reductases | 2004 |
[Current and new therapeutic strategies in acute myeloid leukemia].
Topics: Acute Disease; Aminoglycosides; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Carbazoles; Cytarabine; Disease-Free Survival; Etoposide; fms-Like Tyrosine Kinase 3; Furans; Gemtuzumab; Granulocyte Colony-Stimulating Factor; Humans; Indoles; Leukemia, Myeloid; Mice; Middle Aged; Mitoxantrone; Piperazines; Prognosis; Proto-Oncogene Proteins; Quinazolines; Receptor Protein-Tyrosine Kinases; Vidarabine | 2005 |
Comparative efficacy and safety of gemtuzumab ozogamicin monotherapy and high-dose cytarabine combination therapy in patients with acute myeloid leukemia in first relapse.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Aminoglycosides; Analysis of Variance; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Evaluation; Gemtuzumab; Humans; Leukemia, Myeloid; Middle Aged; Probability; Prognosis; Recurrence; Retrospective Studies; Salvage Therapy; Treatment Outcome | 2003 |
Non-transplant therapy for older adults with acute myeloid leukemia.
Topics: Acute Disease; Age Factors; Aged; Aminoglycosides; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Cytarabine; Cytogenetic Analysis; Gemtuzumab; Humans; Leukemia, Myeloid; Quinolones | 2006 |
Treatment of acute myeloid leukemia in older patients.
Topics: Acute Disease; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Disease Management; Drug Design; Drug Resistance, Neoplasm; Farnesyltranstransferase; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Male; Middle Aged; Neoplasm Proteins; Prognosis; Randomized Controlled Trials as Topic; Receptor, Macrophage Colony-Stimulating Factor; Risk Assessment; Signal Transduction | 2007 |
Timed-sequential chemotherapy as induction and/or consolidation regimen for younger adults with acute myelogenous leukemia.
Topics: Acute Disease; Adolescent; Adult; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Cell Cycle; Child; Cytarabine; Disease-Free Survival; Drug Administration Schedule; Drug Resistance, Neoplasm; Flavonoids; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Middle Aged; Piperidines; Premedication; Prognosis; Rats; Remission Induction; Retrospective Studies; Salvage Therapy; Treatment Outcome | 2007 |
[Acute promyelocytic leukemia. Review of the literature].
Topics: Acute Disease; Adolescent; Adult; Aged; Anemia; Antibiotics, Antineoplastic; Child; Child, Preschool; Cytarabine; Daunorubicin; Disseminated Intravascular Coagulation; Female; Heparin; Humans; Inclusion Bodies; Leukemia, Myeloid, Acute; Male; Middle Aged; Naphthacenes; Neoplastic Stem Cells; Thioguanine; Translocation, Genetic | 1984 |
Therapy in childhood acute nonlymphocytic leukemia (ANLL). Evolution of current concepts of chemotherapy.
Topics: Acute Disease; Adolescent; Adult; Asparaginase; Azauridine; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia; Prednisone; Thioguanine; Thioinosine; Vincristine | 1981 |
Methods for evaluating response to treatment in adult acute leukemia.
Topics: Acute Disease; Adult; Aging; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Clinical Trials as Topic; Cytarabine; Doxorubicin; Drug Therapy, Combination; Glycopeptides; Humans; Leukemia; Models, Biological; Peptide Fragments; Prednisone; Pro-Opiomelanocortin; Prognosis; Prospective Studies; Regression Analysis; Vincristine | 1983 |
Adult acute nonlymphocytic leukemia.
Topics: Acute Disease; Adult; Aged; Antigens, Neoplasm; Antigens, Surface; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cytarabine; Daunorubicin; Humans; Leukemia; Meningeal Neoplasms; Methotrexate; Middle Aged; Thioguanine | 1984 |
[Symposium on treatment of cancer. 1. Chemotherapy of acute leukemia in adults].
Topics: Aclarubicin; Acute Disease; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Clinical Trials as Topic; Cytarabine; Doxorubicin; Humans; Interferon Type I; Leukemia; Middle Aged; Naphthacenes | 1984 |
[Chemotherapy of acute leukemia].
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; DNA, Neoplasm; Drug Administration Schedule; Drug Tolerance; Female; Humans; Leukemia; Male; Middle Aged | 1984 |
Adult acute nonlymphocytic leukemias.
Topics: Acute Disease; Aged; Anemia; Anemia, Aplastic; Anemia, Sideroblastic; Blood Transfusion; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Drug Resistance; Female; Hemorrhage; Humans; Immunotherapy; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Platelet Transfusion; Spinal Cord; Syndrome | 1980 |
[The clinical significance of the Philadelphia chromosome in acute leukaemia (author's transl)].
Topics: Acute Disease; Adult; Blood Transfusion; Chromosomes, Human, 21-22 and Y; Cytarabine; Female; Glucocorticoids; Hematopoietic Stem Cells; Humans; Leukapheresis; Leukemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Vincristine | 1980 |
Infectious complications in leukemic patients.
Topics: Acute Disease; Aminoglycosides; Anti-Bacterial Agents; Antibody Formation; Bacterial Infections; Clostridium Infections; Corynebacterium Infections; Cytarabine; Drug Synergism; Hepatitis A; Hepatitis B; Herpes Zoster; Humans; Immunity, Cellular; Legionnaires' Disease; Leukemia; Methicillin; Mycoses; Pseudomonas Infections; Staphylococcal Infections | 1982 |
Overview of progress in hematology in 1981 with special reference to leukocyte.
Topics: Aclarubicin; Acute Disease; Adult; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Cells, Cultured; Child; Cytarabine; Deoxycytidine Monophosphate; Drug Therapy, Combination; Humans; Kinetics; Leukemia; Leukemia L1210; Leukocytes; Naphthacenes | 1982 |
Current experience with antiviral therapy for acute herpes zoster.
Topics: Acute Disease; Acyclovir; Adult; Antiviral Agents; Cytarabine; Herpes Zoster; Humans; Idoxuridine; Interferons; Middle Aged; Steroids; Vidarabine | 1994 |
New perspectives in the treatment of acute myeloid leukemia by hematopoietic growth factors.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Clinical Trials as Topic; Colony-Stimulating Factors; Cytarabine; DNA Polymerase II; Drug Screening Assays, Antitumor; Drug Synergism; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-3; Leukemia, Myeloid; Neutropenia; Randomized Controlled Trials as Topic; Survival Analysis | 1994 |
A syndrome of lymphoblastic lymphoma, eosinophilia, and myeloid hyperplasia/malignancy associated with t(8;13)(p11;q11): description of a distinctive clinicopathologic entity.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transplantation; Carboplatin; Chromosomes, Human, Pair 13; Chromosomes, Human, Pair 8; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Eosinophilia; Etoposide; Fatal Outcome; Female; Humans; Hydroxyurea; Hyperplasia; Ifosfamide; Leukemia, Myeloid; Lymph Nodes; Male; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Pregnancy; Pregnancy Complications, Neoplastic; Remission Induction; Syndrome; Translocation, Genetic; Vincristine | 1995 |
Acute myeloid leukaemia in the elderly: biology and treatment.
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Leukemia, Myeloid; Palliative Care; Prognosis | 1993 |
rHuGM-CSF after high-dose chemotherapy in post-remission acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Etoposide; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recombinant Proteins | 1995 |
Experimental basis for the use of recombinant human granulocyte-macrophage colony-stimulating factor in patients with acute myeloid leukemia.
Topics: Acute Disease; Cytarabine; Cytokines; DNA-Directed DNA Polymerase; Drug Screening Assays, Antitumor; Drug Synergism; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Lymphocyte Activation; Recombinant Proteins; S Phase | 1994 |
Long term remission of acute myeloid leukaemia with trilineage myelodysplasia treated solely with low dose cytarabine.
Topics: Acute Disease; Cytarabine; Humans; Leukemia, Myeloid; Male; Middle Aged; Myelodysplastic Syndromes; Remission Induction; Time Factors | 1994 |
[State of the art of chemotherapy for adult acute leukemia in Japan].
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Humans; Japan; Leukemia; Mercaptopurine; Middle Aged; Multicenter Studies as Topic; Prednisolone; Remission Induction; Survival Rate | 1993 |
Two additional cases of acute myeloid leukemia with t(7;11)(p15;p15) having low neutrophil alkaline phosphatase scores.
Topics: Acute Disease; Adult; Alkaline Phosphatase; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 7; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Neutrophils; Prednisolone; Primary Myelofibrosis; Remission Induction; Translocation, Genetic | 1993 |
Intravenous mercaptopurine: life begins at 40.
Topics: Acute Disease; Animals; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Infusions, Intravenous; Leukemia; Mercaptopurine; Methotrexate | 1993 |
Growth factors in the management of adult acute leukemia.
Topics: Acute Disease; Adjuvants, Immunologic; Adult; Aged; Antineoplastic Agents; Bone Marrow Diseases; Cell Differentiation; Clinical Trials as Topic; Cytarabine; Drug Evaluation; Growth Substances; Hematopoietic Cell Growth Factors; Hematopoietic Stem Cells; Humans; Immunologic Factors; Leukemia; Middle Aged | 1993 |
Treatment of the newly diagnosed adult with de novo acute myeloid leukemia.
Topics: Acute Disease; Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Drug Evaluation; Etoposide; Humans; Leukemia, Myeloid; Middle Aged; Prognosis; Remission Induction; Transplantation, Autologous | 1993 |
Modulation of cytotoxicity and differentiation-inducing potential of arabinofuranosylcytosine in myeloid leukemia cells by hematopoietic cytokines.
Topics: Acute Disease; Arabinofuranosylcytosine Triphosphate; Cell Differentiation; Cell Division; Colony-Stimulating Factors; Cytarabine; Drug Combinations; Growth Inhibitors; Hematopoietic Cell Growth Factors; Humans; Interleukin-6; Leukemia Inhibitory Factor; Leukemia, Myeloid; Lymphokines; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1993 |
Is intensive treatment beneficial to elderly patients with ANLL?
Topics: Acute Disease; Aged; Cytarabine; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Prognosis; Recurrence; Remission Induction | 1993 |
Treatment of acute myeloid leukemia with antecedent myelodysplastic syndrome.
Topics: Acute Disease; Aged; Antineoplastic Agents; Clinical Trials as Topic; Cytarabine; Humans; Leukemia, Myeloid; Middle Aged; Morbidity; Myelodysplastic Syndromes; Survival Rate | 1996 |
New chemotherapeutic agents in acute myeloid leukemia.
Topics: Acute Disease; Antibodies, Monoclonal; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cytarabine; Hematopoietic Stem Cell Transplantation; Humans; Immunotoxins; Leukemia, Myeloid; Oligonucleotides, Antisense; Retinoids; Vidarabine | 1996 |
Does it matter how remission is achieved in acute leukemia?
Topics: Acute Disease; Adult; Antineoplastic Agents; Cytarabine; Disease-Free Survival; Drug Resistance, Neoplasm; Humans; Leukemia, Myeloid; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Remission Induction; Salvage Therapy; Time Factors | 1996 |
Multidrug resistance in acute myeloid leukaemia.
Topics: Acute Disease; Antimetabolites, Antineoplastic; Cytarabine; DNA Topoisomerases, Type II; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Leukemia, Myeloid; Phenotype | 1996 |
High-dose chemotherapy in adult acute myeloid leukemia: rationale and results.
Topics: Acute Disease; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Leukemia, Myeloid; Middle Aged; Randomized Controlled Trials as Topic; Remission Induction | 1996 |
Curative chemotherapy for acute myeloid leukemia: the development of high-dose ara-C from the laboratory to bedside.
Topics: Acute Disease; Animals; Antimetabolites, Antineoplastic; Cytarabine; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Leukemia L1210; Leukemia, Myeloid; Mice; Randomized Controlled Trials as Topic | 1996 |
Treatment of adult acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Clinical Trials as Topic; Combined Modality Therapy; Cytarabine; Hematopoietic Cell Growth Factors; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Mice; Middle Aged; Multicenter Studies as Topic; Remission Induction; Risk Factors; Survival Analysis | 1997 |
High-dose cytosine arabinoside in the treatment of acute myeloid leukaemia.
Topics: Acute Disease; Antimetabolites, Antineoplastic; Cytarabine; Humans; Leukemia, Myeloid | 1997 |
Intensified induction chemotherapy with high dose cytarabine and etoposide for acute myeloid leukemia: a review and updated results of the Australian Leukemia Study Group.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Etoposide; Humans; Leukemia, Myeloid; Remission Induction | 1998 |
A systematic collaborative overview of randomized trials comparing idarubicin with daunorubicin (or other anthracyclines) as induction therapy for acute myeloid leukaemia. AML Collaborative Group.
Topics: Acute Disease; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Randomized Controlled Trials as Topic; Remission Induction; Survival Analysis | 1998 |
Es nucleoside transporter content of acute leukemia cells: role in cell sensitivity to cytarabine (araC).
Topics: Acute Disease; Antimetabolites, Antineoplastic; Carrier Proteins; Cytarabine; Drug Resistance, Neoplasm; Flow Cytometry; Fluoresceins; Gene Expression; Humans; Leukemia, Myeloid, Acute; Lymphocytes; Membrane Proteins; Microscopy, Confocal; Nucleoside Transport Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Purine Nucleosides | 1998 |
Tailoring the treatment of acute myeloid leukemia.
Topics: Acute Disease; Antimetabolites, Antineoplastic; Bone Marrow Transplantation; Cytarabine; Humans; Leukemia, Myeloid | 1999 |
The management of neoplastic disorders of haematopoiesis in children with Down's syndrome.
Topics: Acute Disease; Adolescent; Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cytarabine; Daunorubicin; Disease-Free Survival; Down Syndrome; Female; Genetic Predisposition to Disease; Humans; Infant; Infant, Newborn; Leukemia; Leukemia, Myeloid; Male; Maternal Age; Myeloproliferative Disorders; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Vincristine | 2000 |
Acute myeloid leukaemia (AML): treatment of the older patient.
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid; Middle Aged; Treatment Outcome | 2001 |
Nucleoside analogues: mechanisms of drug resistance and reversal strategies.
Topics: 2-Chloroadenosine; 5'-Nucleotidase; Acute Disease; Animals; Antimetabolites, Antineoplastic; Arabinonucleosides; Biological Transport; Carrier Proteins; Cytarabine; Cytidine Deaminase; Cytosine; Deoxyadenosines; Deoxycytidine; Deoxycytidine Kinase; Dioxolanes; DNA Repair; DNA Replication; DNA-Directed DNA Polymerase; Drug Resistance, Neoplasm; Gemcitabine; Hematopoietic Cell Growth Factors; Humans; Leukemia, Myeloid; Lymphoproliferative Disorders; Neoplastic Stem Cells; Nucleosides; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Remission Induction; Ribonucleotide Reductases; Vidarabine | 2001 |
Secondary acute myelogenous leukemia and myelodysplasia without abnormalities of chromosome 11q23 following treatment of acute leukemia with topoisomerase II-based chemotherapy.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosomes, Human, Pair 11; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cytarabine; Disease Progression; Disease-Free Survival; Enzyme Inhibitors; Etoposide; Female; Humans; Idarubicin; Incidence; Karyotyping; Leukemia, Myeloid; Life Tables; Male; Middle Aged; Mitoxantrone; Myelodysplastic Syndromes; Neoplasm Proteins; Neoplasms, Second Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Randomized Controlled Trials as Topic; Remission Induction; Retrospective Studies; Topoisomerase II Inhibitors; Treatment Outcome; Tretinoin | 2001 |
A systematic overview of chemotherapy effects in acute myeloid leukaemia.
Topics: Acute Disease; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Humans; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Neoplasms, Second Primary; Prognosis; Prospective Studies; Randomized Controlled Trials as Topic; Retrospective Studies; Treatment Outcome | 2001 |
Acute myeloid leukemia in adults: where do we go from here?
Topics: Acute Disease; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Combined Modality Therapy; Cytarabine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Middle Aged; Randomized Controlled Trials as Topic | 2001 |
The role of purine analogue combinations in the management of acute leukemias.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Synergism; Humans; Leukemia; Purines | 2001 |
Philadelphia chromosome-positive acute myeloid leukemia with tetraploidy.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cytarabine; Daunorubicin; Fusion Proteins, bcr-abl; Humans; Karyotyping; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Mercaptopurine; Middle Aged; Mitoxantrone; Polyploidy; Prednisolone; Remission Induction; RNA, Messenger; RNA, Neoplasm | 2002 |
Approaches to the treatment of acute leukemia and lymphoma in adults.
Topics: Acute Disease; Adult; Animals; BCG Vaccine; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Environment, Controlled; Humans; Immunotherapy; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma; Mice; Prednisone; Vincristine | 1978 |
Early consolidation chemotherapy for adults with acute leukemia in remission.
Topics: Acute Disease; Adolescent; Adult; Anti-Bacterial Agents; Antineoplastic Agents; Bacterial Infections; Cytarabine; Enterocolitis, Pseudomembranous; Female; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Necrosis; Prednisone; Remission, Spontaneous; Vincristine | 1976 |
Hematopoietins in combination with 1-beta-D-arabinofuranosylcytosine: a possible strategy for improved treatment of myeloid disorders.
Topics: Acute Disease; Antineoplastic Agents; Cytarabine; Drug Synergism; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Cell Growth Factors; Humans; Interleukin-3; Leukemia, Myeloid; Leukemia, Myeloid, Acute; S Phase | 1992 |
Improved cure rate by very early intensification combined with prolonged maintenance chemotherapy in patients with acute myeloid leukemia: data from the AML Cooperative Group.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid; Remission Induction; Thioguanine | 1991 |
New agents in the treatment of acute myeloid leukemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cytarabine; Daunorubicin; Drug Evaluation; Etoposide; Humans; Idarubicin; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Remission Induction; Tretinoin | 1991 |
[Acute pericarditis caused by daunorubicin in acute myelocytic leukemia].
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Pericarditis | 1988 |
New strategies in the management of acute leukemias.
Topics: Acute Disease; Amsacrine; Aneuploidy; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Drug Evaluation; Humans; Leukemia; Leukemia, Lymphoid; Myelodysplastic Syndromes; Prognosis; Remission Induction | 1987 |
Current status of treatment of acute leukemia in adults: an overview of the Memorial experience and review of literature.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Examination; Cytarabine; Female; Humans; Leukemia; Leukemia, Lymphoid; Male; Middle Aged; Prognosis; Recurrence; Thioguanine; Time Factors | 1986 |
Indications for and benefits of intensive therapies in treatment of childhood cancers.
Topics: Acute Disease; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Etoposide; Humans; Leukemia; Leukemia, Lymphoid; Lymphoma; Melphalan; Methotrexate; Neoplasms; Osteosarcoma; Risk; Sarcoma, Ewing | 1986 |
A critical appraisal of low-dose cytosine arabinoside in patients with acute non-lymphocytic leukemia and myelodysplastic syndromes.
Topics: Acute Disease; Adolescent; Adult; Aged; Bone Marrow; Child; Cytarabine; Follow-Up Studies; Humans; Leukemia; Leukocyte Count; Middle Aged; Myelodysplastic Syndromes; Platelet Count | 1986 |
Antiviral chemotherapy: the first decade.
Topics: Acute Disease; Amantadine; Antiviral Agents; Chickenpox; Chronic Disease; Cytarabine; Herpes Simplex; Herpes Zoster; Humans; Idoxuridine; Influenza, Human; Molluscum Contagiosum; Semicarbazones; Smallpox; Vaccinia; Warts | 1973 |
[Treatment of acute leukemias].
Topics: Acute Disease; Adult; Age Factors; Antineoplastic Agents; Asparaginase; Child; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methods; Methotrexate; Prednisolone; Recurrence; Remission, Spontaneous; Vincristine | 1973 |
[Achievements in the treatment of leukemia and lymphoma].
Topics: Acute Disease; Animals; Antineoplastic Agents; Burkitt Lymphoma; Chemical Phenomena; Chemistry; Cytarabine; Drug Therapy, Combination; Humans; Immunotherapy; Leukemia; Lymphoma; Methods; Remission, Spontaneous; Time Factors | 1973 |
Immunochemotherapy of human cancer.
Topics: Acute Disease; Adjuvants, Immunologic; Adult; Animals; Antineoplastic Agents; BCG Vaccine; Cytarabine; Humans; Immunosuppressive Agents; Immunotherapy; Leukemia L1210; Lymphoma; Melanoma; Mice; Neoplasms; Neoplasms, Experimental; Prednisone; Vincristine | 1974 |
[Burkitt's lymphoma and acute leukemias].
Topics: Acute Disease; Animals; Asparaginase; Burkitt Lymphoma; Child; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Fluorouracil; Humans; Leukemia; Melphalan; Mercaptopurine; Methotrexate; Mice; Oncogenic Viruses; Prednisolone; Prednisone; Vincristine | 1969 |
Changing concepts of treatment in acute leukemia.
Topics: Acute Disease; Animals; Antineoplastic Agents; Asparaginase; Cell Differentiation; Cell Division; Cytarabine; DNA; Erythropoiesis; Hematopoiesis; Humans; Immunosuppressive Agents; Kinetics; Leukemia; Leukemia, Experimental; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Mice; Mitosis; Models, Biological; Oncogenic Viruses; Prednisone; Remission, Spontaneous; Time Factors | 1971 |
323 trial(s) available for cytarabine and Acute Disease
| Article | Year |
|---|---|
FLA-IDA salvage chemotherapy combined with a seven-day course of venetoclax (FLAVIDA) in patients with relapsed/refractory acute leukaemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia; Male; Middle Aged; Recurrence; Salvage Therapy; Sulfonamides; Vidarabine | 2020 |
Clofarabine increases the eradication of minimal residual disease of primary B-precursor acute lymphoblastic leukemia compared to high-dose cytarabine without improvement of outcome. Results from the randomized clinical trial 08-09 of the Cooperative Acut
Topics: Acute Disease; Antineoplastic Agents; Child; Clofarabine; Cytarabine; Disease-Free Survival; Humans; Lymphoma, Non-Hodgkin; Neoplasm, Residual; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome | 2022 |
A Phase II Study of CLAG Regimen Combined With Imatinib Mesylate for Relapsed or Refractory Acute Myeloid Leukemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cytarabine; Diarrhea; Drug Resistance, Neoplasm; Edema; Female; Granulocyte Colony-Stimulating Factor; Humans; Imatinib Mesylate; Kaplan-Meier Estimate; Leukemia, Myeloid; Male; Middle Aged; Nausea; Neoplasm Recurrence, Local; Remission Induction; Salvage Therapy; Treatment Outcome | 2017 |
Thalidomide in Combination with Chemotherapy in Treating Elderly Patients with Acute Myeloid Leukemia.
Topics: Aclarubicin; Acute Disease; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy-Induced Febrile Neutropenia; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid; Male; Middle Aged; Outcome Assessment, Health Care; Proportional Hazards Models; Prospective Studies; Remission Induction; Thalidomide | 2018 |
Outcome of relapse in children and adolescents with B-cell non-Hodgkin lymphoma and mature acute leukemia: A report from the French LMB study.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Carboplatin; Child; Child, Preschool; Cytarabine; Disease-Free Survival; Etoposide; Female; Follow-Up Studies; France; Humans; Ifosfamide; Infant; Leukemia; Lymphoma, Large B-Cell, Diffuse; Male; Prospective Studies; Recurrence; Rituximab; Survival Rate | 2019 |
Sequential combination of gemtuzumab ozogamicin and standard chemotherapy in older patients with newly diagnosed acute myeloid leukemia: results of a randomized phase III trial by the EORTC and GIMEMA consortium (AML-17).
Topics: Acute Disease; Aged; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Etoposide; Febrile Neutropenia; Female; Follow-Up Studies; Gemtuzumab; Humans; Induction Chemotherapy; Infections; Leukemia, Myeloid; Liver; Male; Middle Aged; Mitoxantrone; Remission Induction; Survival Analysis; Treatment Outcome | 2013 |
No impact of high-dose cytarabine and asparaginase as early intensification with intermediate-risk paediatric acute lymphoblastic leukaemia: results of randomized trial TCCSG study L99-15.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Infant; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Risk Factors; Survival Rate; Treatment Outcome | 2014 |
Low dose interleukin-2 following intensification therapy with high dose cytarabine for acute myelogenous leukemia in first complete remission.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Dose-Response Relationship, Drug; Fatigue; Feasibility Studies; Female; Fever; Follow-Up Studies; Humans; Interleukin-2; Killer Cells, Natural; Leukemia, Myeloid; Male; Middle Aged; Recombinant Proteins; Remission Induction; Survival Analysis; T-Lymphocytes; Thrombocytopenia; Time Factors; Treatment Outcome | 2008 |
CTLA-4 genotype and relapse incidence in patients with acute myeloid leukemia in first complete remission after induction chemotherapy.
Topics: 3' Untranslated Regions; Acute Disease; Adolescent; Adult; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; CTLA-4 Antigen; Cytarabine; Disease-Free Survival; Etoposide; Female; Genotype; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Incidence; Kaplan-Meier Estimate; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Neoplasm Proteins; Polymorphism, Single Nucleotide; Proportional Hazards Models; Recurrence; Remission Induction; Young Adult | 2009 |
Combination of cladribine and cytarabine is effective for childhood acute myeloid leukemia: results of the St Jude AML97 trial.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cladribine; Combined Modality Therapy; Cytarabine; Daunorubicin; Down Syndrome; Drug Administration Schedule; Etoposide; Hematopoietic Stem Cell Transplantation; Humans; Infant; Kaplan-Meier Estimate; Leukemia, Myeloid; Myelodysplastic Syndromes; Prognosis; Proportional Hazards Models; Remission Induction; Young Adult | 2009 |
Phase I/II trial of AEG35156 X-linked inhibitor of apoptosis protein antisense oligonucleotide combined with idarubicin and cytarabine in patients with relapsed or primary refractory acute myeloid leukemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Oligonucleotides; Peripheral Nervous System Diseases; Recurrence; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Treatment Outcome; X-Linked Inhibitor of Apoptosis Protein | 2009 |
Citrulline as a marker for chemotherapy induced mucosal barrier injury in pediatric patients.
Topics: Acute Disease; Adolescent; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Carbohydrates; Cell Death; Child; Child, Preschool; Citrulline; Cytarabine; Daunorubicin; DNA; Enterocytes; Etoposide; Feces; Female; Humans; Infant; Interleukin-8; Intestinal Absorption; Leukemia, Myeloid; Leukocyte L1 Antigen Complex; Male; Mitoxantrone; Models, Biological; Mucositis; Stomatitis | 2009 |
Daunorubicin versus mitoxantrone versus idarubicin as induction and consolidation chemotherapy for adults with acute myeloid leukemia: the EORTC and GIMEMA Groups Study AML-10.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Remission Induction; Survival Analysis; Survival Rate; Treatment Outcome; Young Adult | 2009 |
Mitoxantrone and etoposide in patients with newly diagnosed acute myeloid leukemia with persistent leukemia after a course of therapy with cytarabine and idarubicin.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Neutropenia; Prognosis; Remission Induction; Retrospective Studies; Survival Analysis; Survival Rate; Treatment Outcome; Young Adult | 2009 |
Infusion of HLA-mismatched peripheral blood stem cells improves the outcome of chemotherapy for acute myeloid leukemia in elderly patients.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Histocompatibility; Histocompatibility Testing; HLA Antigens; Humans; Infections; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Peripheral Blood Stem Cell Transplantation; Transplantation Chimera; Treatment Outcome | 2011 |
Continuous sequential infusion of fludarabine and cytarabine for elderly patients with acute myeloid leukaemia secondary to a previously diagnosed myelodysplastic syndrome.
Topics: Acute Disease; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Diarrhea; Disease-Free Survival; Female; Hematopoietic Stem Cell Transplantation; Humans; Infusions, Intravenous; Leukemia, Myeloid; Male; Middle Aged; Myelodysplastic Syndromes; Remission Induction; Transplantation, Autologous; Treatment Outcome; Vidarabine | 2010 |
Phase 1 and pharmacokinetic study of bolus-infusion flavopiridol followed by cytosine arabinoside and mitoxantrone for acute leukemias.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Flavonoids; Humans; Infusion Pumps; Leukemia; Male; Middle Aged; Mitoxantrone; Piperidines; Young Adult | 2011 |
Early allo-SCT for AML with a complex aberrant karyotype--results from a prospective pilot study.
Topics: Abnormal Karyotype; Acute Disease; Adolescent; Adult; Amsacrine; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Disease-Free Survival; Female; Follow-Up Studies; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Lymphocyte Depletion; Male; Middle Aged; Pilot Projects; Prospective Studies; Survival Rate; Transplantation Conditioning; Transplantation, Homologous; Vidarabine | 2012 |
Phase 1 study of epigenetic priming with decitabine prior to standard induction chemotherapy for patients with AML.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Daunorubicin; Decitabine; Diarrhea; DNA Methylation; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fever; Humans; Infections; Kaplan-Meier Estimate; Leukemia, Myeloid; Male; Middle Aged; Nausea; Neutropenia; Treatment Outcome; Young Adult | 2011 |
Phase I and pharmacological study of cytarabine and tanespimycin in relapsed and refractory acute leukemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Benzoquinones; Checkpoint Kinase 1; Cytarabine; Female; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Leukemia; Male; Middle Aged; Protein Kinases; Recurrence; Time Factors | 2011 |
Natural history of transient myeloproliferative disorder clinically diagnosed in Down syndrome neonates: a report from the Children's Oncology Group Study A2971.
Topics: Acute Disease; Antimetabolites, Antineoplastic; Cytarabine; Disease Progression; Down Syndrome; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Kaplan-Meier Estimate; Leukemia, Megakaryoblastic, Acute; Leukemia, Myeloid; Male; Myeloproliferative Disorders; Prognosis; Prospective Studies; Time Factors; Treatment Outcome | 2011 |
[Clinical study of kangai injection plus FLAG regimen for refractory/relapsed acute leukemia].
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drugs, Chinese Herbal; Female; Granulocyte Colony-Stimulating Factor; Humans; Injections; Leukemia; Male; Middle Aged; Vidarabine | 2011 |
Phase I trial and correlative laboratory studies of bryostatin 1 (NSC 339555) and high-dose 1-B-D-arabinofuranosylcytosine in patients with refractory acute leukemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bryostatins; Cytarabine; Female; Humans; Infusions, Intravenous; Lactones; Leukemia, Myeloid; Macrolides; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinase C; Tumor Cells, Cultured | 2002 |
Phase III trial of a humanized anti-CD33 antibody (HuM195) in patients with relapsed or refractory acute myeloid leukemia.
Topics: Acute Disease; Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Etoposide; Fever; Humans; Hypotension; Infections; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Recurrence; Remission Induction; Salvage Therapy; Sialic Acid Binding Ig-like Lectin 3; Survival Rate; Treatment Outcome | 2002 |
Intensified double induction therapy with high dose mitoxantrone, etoposide, m-amsacrine and high dose ara-C for elderly acute myeloid leukemia patients aged 61-65 years.
Topics: Acute Disease; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chemical and Drug Induced Liver Injury; Cytarabine; Disease-Free Survival; Etoposide; Female; Gastrointestinal Diseases; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Life Tables; Male; Middle Aged; Mitoxantrone; Neoplasm Proteins; Neutropenia; Remission Induction; Survival Analysis; Treatment Outcome | 2002 |
FLAG-IDA regimen (fludarabine, cytarabine, idarubicin and G-CSF) in the treatment of patients with high-risk myeloid malignancies.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Infections; Leukemia, Myeloid; Male; Middle Aged; Myelodysplastic Syndromes; Recombinant Proteins; Remission Induction; Risk Factors; Survival Analysis; Treatment Outcome; Vidarabine | 2002 |
Postremission therapy with low-dose interleukin 2 with or without intermediate pulse dose interleukin 2 therapy is well tolerated in elderly patients with acute myeloid leukemia: Cancer and Leukemia Group B study 9420.
Topics: Acute Disease; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclosporins; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Administration Schedule; Etoposide; Fatigue; Gene Expression Regulation, Neoplastic; Hematologic Diseases; Humans; Immunologic Factors; Interleukin-2; Killer Cells, Natural; Leukemia, Myeloid; Life Tables; Middle Aged; Nausea; Neoplasm Proteins; NK Cell Lectin-Like Receptor Subfamily K; Receptors, Immunologic; Receptors, Natural Killer Cell; Recombinant Fusion Proteins; Remission Induction; Survival Analysis; Treatment Outcome | 2002 |
Peripheral blood stem cell collection in children with acute leukemia: effectiveness of the 'DIAVE' mobilizing regimen.
Topics: Acute Disease; Adolescent; Adult; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Cell Count; Child; Child, Preschool; Cytarabine; Dexamethasone; Etoposide; Graft Survival; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Humans; Idarubicin; Leukapheresis; Leukemia; Peripheral Blood Stem Cell Transplantation; Vincristine | 2002 |
Phase 1 and pharmacodynamic studies of G3139, a Bcl-2 antisense oligonucleotide, in combination with chemotherapy in refractory or relapsed acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Down-Regulation; Female; Genes, bcl-2; Granulocyte Colony-Stimulating Factor; Humans; Leukemia; Male; Middle Aged; Oligonucleotides, Antisense; Remission Induction; Salvage Therapy; Thionucleotides; Vidarabine | 2003 |
Outcome after induction chemotherapy for older patients with acute myeloid leukemia is not improved with mitoxantrone and etoposide compared to cytarabine and daunorubicin: a Southwest Oncology Group study.
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Remission Induction; Survival Analysis; Survival Rate; Treatment Outcome | 2002 |
Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B (CALGB 8461).
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosome Inversion; Chromosomes, Human; Cytarabine; Daunorubicin; Disease-Free Survival; Follow-Up Studies; Humans; Incidence; Karyotyping; Leukemia, Myeloid; Life Tables; Prospective Studies; Recurrence; Remission Induction; Risk Factors; Survival Analysis; Translocation, Genetic; Treatment Outcome; Trisomy | 2002 |
Impact of granulocyte colony-stimulating factor use during induction for acute myelogenous leukemia in children: a report from the Children's Cancer Group.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Child; Cytarabine; Daunorubicin; Dexamethasone; Disease-Free Survival; Etoposide; Female; Filgrastim; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Humans; Hyperbilirubinemia; Infection Control; Length of Stay; Leukemia, Myeloid; Male; Neutropenia; Prospective Studies; Recombinant Proteins; Remission Induction; Survival Analysis; Thioguanine; Thrombocytosis; Treatment Outcome | 2002 |
Mylotarg combined with topotecan and cytarabine in patients with refractory acute myelogenous leukemia.
Topics: Acute Disease; Adult; Aged; Aminoglycosides; Anti-Bacterial Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Gemtuzumab; Humans; Infusions, Intravenous; Leukemia, Myeloid; Middle Aged; Neoplasm Recurrence, Local; Pilot Projects; Remission Induction; Salvage Therapy; Sialic Acid Binding Ig-like Lectin 3; Survival Rate; Topotecan; Treatment Outcome | 2002 |
A phase I/II study of the MDR modulator Valspodar (PSC 833) combined with daunorubicin and cytarabine in patients with relapsed and primary refractory acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cause of Death; Cyclosporins; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Humans; Leukemia, Myeloid; Middle Aged; Remission Induction; Salvage Therapy; Treatment Outcome | 2003 |
The treatment of acute myeloid leukemia with mitoxantrone, etoposide and low-dose cytarabine in elderly patients - a report of Polish Acute Leukemia Group (PALG) phase II study.
Topics: Acute Disease; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Etoposide; Female; Humans; Leukemia, Myeloid; Leukocyte Count; Male; Middle Aged; Mitoxantrone; Poland; Prognosis; Prospective Studies; Remission Induction; Survival Rate | 2002 |
Adaptive randomized study of idarubicin and cytarabine versus troxacitabine and cytarabine versus troxacitabine and idarubicin in untreated patients 50 years or older with adverse karyotype acute myeloid leukemia.
Topics: Acute Disease; Age Factors; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Cytosine; Dioxolanes; Female; Humans; Idarubicin; Infusions, Intravenous; Karyotyping; Leukemia, Myeloid; Male; Middle Aged; Prognosis; Survival; Treatment Outcome | 2003 |
BAALC expression predicts clinical outcome of de novo acute myeloid leukemia patients with normal cytogenetics: a Cancer and Leukemia Group B Study.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Genetic Markers; Genetic Predisposition to Disease; Humans; Karyotyping; Leukemia, Myeloid; Male; Middle Aged; Multivariate Analysis; Neoplasm Proteins; Predictive Value of Tests; Prognosis; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; Treatment Outcome | 2003 |
Treatment stratification based on initial in vivo response in acute myeloid leukaemia in children without Down's syndrome: results of NOPHO-AML trials.
Topics: Acute Disease; Antimetabolites, Antineoplastic; Child; Child, Preschool; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 9; Clinical Protocols; Cytarabine; Cytogenetic Analysis; Disease-Free Survival; Drug Administration Schedule; Female; Humans; Infant; Leukemia, Myeloid; Male; Patient Selection; Prognosis; Remission Induction; Stem Cell Transplantation; Survival Rate; Translocation, Genetic | 2003 |
Gemtuzumab ozogamicin, fludarabine, cytarabine and cyclosporine combination regimen in patients with CD33+ primary resistant or relapsed acute myeloid leukemia.
Topics: Acute Disease; Adult; Aged; Aminoglycosides; Anti-Bacterial Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antineoplastic Combined Chemotherapy Protocols; Cyclosporine; Cytarabine; Drug Resistance, Neoplasm; Female; Gemtuzumab; Humans; Leukemia, Myeloid; Male; Middle Aged; Platelet Count; Recurrence; Remission Induction; Sialic Acid Binding Ig-like Lectin 3; Survival Rate; Vidarabine | 2003 |
Risk-adapted postremission therapy in acute myeloid leukemia: results of the German multicenter AML HD93 treatment trial.
Topics: Acute Disease; Adolescent; Adult; Algorithms; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Cytogenetic Analysis; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Remission Induction; Risk Assessment; Stem Cell Transplantation; Survival Analysis | 2003 |
A feasibility study of simultaneous administration of gemtuzumab ozogamicin with intensive chemotherapy in induction and consolidation in younger patients with acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aminoglycosides; Amsacrine; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Chemical and Drug Induced Liver Injury; Cohort Studies; Cytarabine; Doxorubicin; Etoposide; Feasibility Studies; Gemtuzumab; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid; Middle Aged; Pilot Projects; Remission Induction; Thioguanine; Vidarabine | 2003 |
No benefit from adding GM-CSF to induction chemotherapy in transforming myelodysplastic syndromes: better outcome in patients with less proliferative disease.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; Cell Transformation, Neoplastic; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Male; Middle Aged; Myelodysplastic Syndromes; Prospective Studies; Remission Induction; Survival Rate; Thioguanine | 2003 |
Increased remissions from one course for intermediate-dose cytosine arabinoside and idarubicin in elderly acute myeloid leukaemia when combined with cladribine. A randomized population-based phase II study.
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cytarabine; Female; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Remission Induction; Survival Rate | 2003 |
More efficient mobilisation of peripheral blood stem cells with HiDAC+AMSA+G-CSF than with mini-ICE+G-CSF in patients with AML.
Topics: Acute Disease; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Caspase 14; Caspases; Cohort Studies; Combined Modality Therapy; Cytarabine; Etoposide; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Humans; Idarubicin; Leukapheresis; Leukemia, Myeloid; Male; Middle Aged; Peripheral Blood Stem Cell Transplantation; Recombinant Proteins; Transplantation, Autologous | 2003 |
Fludarabine, cytosine arabinoside, granulocyte-colony stimulating factor with or without idarubicin in the treatment of high risk acute leukaemia or myelodysplastic syndromes.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Infusions, Intravenous; Leukemia, Myeloid; Male; Middle Aged; Myelodysplastic Syndromes; Recombinant Proteins; Stem Cell Transplantation; Survival Analysis; Treatment Outcome; Vidarabine | 2004 |
Pilot study of idarubicin-based intensive-timing induction therapy for children with previously untreated acute myeloid leukemia: Children's Cancer Group Study 2941.
Topics: Acute Disease; Adolescent; Adult; Antibiotics, Antineoplastic; Child; Child, Preschool; Cytarabine; Daunorubicin; Dexamethasone; Disease-Free Survival; Drug Administration Schedule; Etoposide; Female; Humans; Idarubicin; Infant; Infant, Newborn; Leukemia, Myeloid; Male; Thioguanine; Treatment Outcome | 2004 |
Autologous peripheral blood stem cell transplantation with BCVAC conditioning in childhood acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Etoposide; Female; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Infant; Infant, Newborn; Leukemia, Myeloid; Male; Prognosis; Recurrence; Risk Factors; Transplantation Conditioning | 2004 |
Granulocyte-macrophage colony-stimulating factor to increase efficacy of mitoxantrone, etoposide and cytarabine in previously untreated elderly patients with acute myeloid leukaemia: a Swedish multicentre randomized trial.
Topics: Acute Disease; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Neutropenia; Opportunistic Infections; Remission Induction; Survival Analysis | 2004 |
Repetitive cycles of high-dose cytarabine benefit patients with acute myeloid leukemia and inv(16)(p13q22) or t(16;16)(p13;q22): results from CALGB 8461.
Topics: Acute Disease; Adolescent; Adult; Analysis of Variance; Antimetabolites, Antineoplastic; Chromosome Inversion; Chromosomes, Human, Pair 16; Cytarabine; Disease-Free Survival; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Proportional Hazards Models; Recurrence; Survival Analysis; Translocation, Genetic; United States | 2004 |
Maintenance therapy in childhood acute myeloid leukemia.
Topics: Acute Disease; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Child; Chromosome Aberrations; Cytarabine; Disease-Free Survival; Humans; Leukemia, Myeloid; Mercaptopurine; Mitoxantrone; Prognosis; Survival Analysis; Time Factors | 2004 |
Intensive chemotherapy with idarubicin, cytarabine, etoposide, and G-CSF priming in patients with advanced myelodysplastic syndrome and high-risk acute myeloid leukemia.
Topics: Acute Disease; Adult; Aged; Amsacrine; Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Myelodysplastic Syndromes; Remission Induction; Risk; Survival Rate; Treatment Outcome | 2004 |
Phase I/II clinical study of topotecan and cytarabine in patients with myelodysplastic syndrome, chronic myelomonocytic leukemia and acute myeloid leukemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Cytarabine; Disease-Free Survival; Female; Hemoglobinometry; Humans; Leukemia, Myeloid; Leukemia, Myelomonocytic, Chronic; Male; Middle Aged; Myelodysplastic Syndromes; Remission Induction; Survival Analysis; Topotecan; Treatment Outcome | 2004 |
Low-dose ARAC, donor cells, and GM-CSF for treatment of recurrent acute myeloid leukemia after allogeneic stem cell transplantation.
Topics: Acute Disease; Adolescent; Adult; Cytarabine; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Lymphocyte Transfusion; Male; Middle Aged; Recurrence; Survival Analysis; Transplantation, Homologous | 2004 |
A randomized trial of high-versus conventional-dose cytarabine in consolidation chemotherapy for adult de novo acute myeloid leukemia in first remission after induction therapy containing high-dose cytarabine.
Topics: Acute Disease; Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Remission Induction; Treatment Outcome | 2005 |
[Consolidation of therapy of acute myeloid leukemia with the AML-BFM 93 protocol in children in the Czech Republic].
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Infant; Leukemia, Myeloid; Male | 2004 |
First experience with gemtuzumab ozogamicin plus cytarabine as continuous infusion for elderly acute myeloid leukaemia patients.
Topics: Acute Disease; Aged; Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Gemtuzumab; Hemorrhage; Humans; Leukemia, Myeloid; Middle Aged; Recurrence; Remission Induction; Survival Rate; Treatment Outcome | 2004 |
Feasibility and results of autologous stem cell transplantation in de novo acute myeloid leukemia in patients over 60 years old. Results of the CETLAM AML-99 protocol.
Topics: Acute Disease; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Leukemia, Myeloid; Logistic Models; Male; Middle Aged; Mitoxantrone; Proportional Hazards Models; Remission Induction; Transplantation, Autologous | 2004 |
Increasing dose intensity of anthracycline antibiotics improves outcome in patients with acute myelogenous leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease-Free Survival; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Female; Follow-Up Studies; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Male; Middle Aged; Proportional Hazards Models; Prospective Studies; Remission Induction; Survival Analysis; Treatment Outcome | 2004 |
Combination of liposomal daunorubicin (DaunoXome), fludarabine, and cytarabine (FLAD) in patients with poor-risk acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Risk Factors; Survival Rate; Vidarabine | 2004 |
Phase III study of all-trans retinoic acid in previously untreated patients 61 years or older with acute myeloid leukemia.
Topics: Acute Disease; Aged; Aged, 80 and over; Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Etoposide; Humans; Idarubicin; Leukemia, Myeloid; Middle Aged; Prognosis; Remission Induction; Survival Rate; Transplantation, Homologous; Tretinoin | 2004 |
Results of a phase 1-2 study of clofarabine in combination with cytarabine (ara-C) in relapsed and refractory acute leukemias.
Topics: Acute Disease; Adenine Nucleotides; Aged; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cytarabine; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Karyotyping; Leukemia; Male; Middle Aged; Recurrence; Treatment Outcome | 2005 |
Glomerular dysfunction, independent of tubular dysfunction, induced by antineoplastic chemotherapy in children.
Topics: Acute Disease; Adolescent; Albuminuria; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Creatinine; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Glomerular Filtration Rate; Humans; Kidney Tubules; Leukemia; Lymphoma; Methotrexate; Neoplasms; Neuroblastoma; Osteosarcoma; Proteinuria; Rhabdomyosarcoma; Vincristine | 2004 |
Dose escalation studies of cytarabine, daunorubicin, and etoposide with and without multidrug resistance modulation with PSC-833 in untreated adults with acute myeloid leukemia younger than 60 years: final induction results of Cancer and Leukemia Group B
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclosporins; Cytarabine; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Leukemia, Myeloid; Logistic Models; Male; Middle Aged; Survival Analysis; Treatment Outcome | 2004 |
Outcome of induction and postremission therapy in younger adults with acute myeloid leukemia with normal karyotype: a cancer and leukemia group B study.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Aziridines; Benzoquinones; Cyclophosphamide; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Karyotyping; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Prognosis; Recurrence; Splenomegaly; Survival Analysis; Treatment Outcome | 2005 |
Sequential multiagent chemotherapy is not superior to high-dose cytarabine alone as postremission intensification therapy for acute myeloid leukemia in adults under 60 years of age: Cancer and Leukemia Group B Study 9222.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Cytogenetic Analysis; Disease-Free Survival; Female; Follow-Up Studies; Humans; Leukemia, Myeloid; Male; Middle Aged; Prognosis; Remission Induction; Survival Analysis | 2005 |
Induction chemotherapy for acute myelogenous leukemia.
Topics: Acute Disease; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Administration Schedule; Etoposide; Humans; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Remission Induction; Survival Analysis; Treatment Outcome | 2005 |
Prediction of individual response to chemotherapy in patients with acute myeloid leukaemia using the chemosensitivity index Ci.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Screening Assays, Antitumor; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Predictive Value of Tests; Prospective Studies; Sensitivity and Specificity; Survival Analysis; Thioguanine; Treatment Outcome; Tumor Cells, Cultured | 2005 |
A multicenter, open, noncomparative, phase II study of the combination of cladribine (2-chlorodeoxyadenosine), cytarabine, granulocyte colony-stimulating factor and mitoxantrone as induction therapy in refractory acute myeloid leukemia: a report of the Po
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cytarabine; Drug Therapy, Combination; Female; Granulocyte Colony-Stimulating Factor; Hematologic Diseases; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Remission Induction; Salvage Therapy; Survival Analysis | 2005 |
Sequential administration of irinotecan and cytarabine in the treatment of relapsed and refractory acute myeloid leukemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cytarabine; DNA Damage; DNA Topoisomerases, Type I; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Synergism; Female; HL-60 Cells; Humans; Irinotecan; Leukemia, Myeloid; Male; Middle Aged; Recurrence | 2006 |
Aclarubicin and low-dose Cytosine arabinoside in combination with granulocyte colony-stimulating factor in treating acute myeloid leukemia patients with relapsed or refractory disease and myelodysplastic syndrome: a multicenter study of 112 Chinese patien
Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Female; Granulocyte Colony-Stimulating Factor; Humans; Injections, Subcutaneous; Leukemia, Myeloid; Male; Middle Aged; Myelodysplastic Syndromes; Neutropenia; Survival Analysis; Thrombocytopenia; Treatment Outcome | 2005 |
Twenty years of Polish experience with three consecutive protocols for treatment of childhood acute myelogenous leukemia.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Antineoplastic Protocols; Bone Marrow Transplantation; Cause of Death; Child; Child, Preschool; Cytarabine; Female; Follow-Up Studies; Humans; Idarubicin; Infant; Infant, Newborn; Leukemia, Myeloid; Male; Poland; Remission Induction; Survival Analysis; Treatment Outcome | 2005 |
Pediatric Oncology Group (POG) studies of acute myeloid leukemia (AML): a review of four consecutive childhood AML trials conducted between 1981 and 2000.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Antineoplastic Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Dose-Response Relationship, Drug; Down Syndrome; Follow-Up Studies; Humans; Infant; Infant, Newborn; Leukemia, Myeloid; Prognosis; Remission Induction; Survival Analysis; Treatment Outcome | 2005 |
Low-dose cytosine arabinoside (LD-AraC) vs LD-AraC plus granulocyte/macrophage colony stimulating factor vs LD-AraC plus Interleukin-3 for myelodysplastic syndrome patients with a high risk of developing acute leukemia: final results of a randomized phase
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Injections, Subcutaneous; Interleukin-3; Leukemia; Male; Middle Aged; Myelodysplastic Syndromes; Risk Factors; Treatment Outcome | 2005 |
Multicentre phase III trial on fludarabine, cytarabine (Ara-C), and idarubicin versus idarubicin, Ara-C and etoposide for induction treatment of younger, newly diagnosed acute myeloid leukaemia patients.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Humans; Idarubicin; Karyotyping; Leukemia, Myeloid; Leukocyte Count; Male; Middle Aged; Prospective Studies; Remission Induction; Stem Cell Transplantation; Transplantation Conditioning; Transplantation, Autologous; Treatment Outcome; Vidarabine | 2005 |
Clofarabine and cytarabine combination as induction therapy for acute myeloid leukemia (AML) in patients 50 years of age or older.
Topics: Acute Disease; Adenine Nucleotides; Aged; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Chromosome Aberrations; Clofarabine; Cytarabine; Drug Administration Schedule; Humans; Leukemia, Myeloid; Middle Aged; Remission Induction; Survival Rate; Treatment Outcome | 2006 |
Phase II trial of subcutaneous recombinant human interleukin 11 with subcutaneous recombinant human granulocyte-macrophage colony stimulating factor in patients with acute myeloid leukemia (AML) receiving high-dose cytarabine during induction: ECOG 3997.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Injections, Subcutaneous; Interleukin-11; Leukemia, Myeloid; Male; Middle Aged; Recombinant Proteins; Remission Induction; Survival Rate; Treatment Outcome | 2006 |
Addition of cyclosporin-A to chemotherapy in secondary (post-MDS) AML in the elderly. A multicenter randomized trial of the Leukemia Working Group of the Hellenic Society of Hematology.
Topics: Acute Disease; Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cyclosporine; Cytarabine; Data Interpretation, Statistical; Disease-Free Survival; Etoposide; Female; Follow-Up Studies; Greece; Humans; Idarubicin; Infusions, Intravenous; Leukemia, Myeloid; Male; Middle Aged; Neoplasms, Second Primary; Remission Induction; Societies, Medical; Survival Analysis; Treatment Outcome | 2006 |
Triapine and cytarabine is an active combination in patients with acute leukemia or myelodysplastic syndrome.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Female; Humans; Injections, Intravenous; Leukemia, Myeloid; Male; Maximum Tolerated Dose; Middle Aged; Myelodysplastic Syndromes; Pyridines; Recurrence; Risk Factors; Thiosemicarbazones; Treatment Outcome | 2006 |
Remission induction chemotherapy induces in vivo caspase-dependent apoptosis in bone marrow acute myeloid leukemia blast cells and spares lymphocytes.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Agents; Apoptosis; Bone Marrow Cells; Bone Marrow Transplantation; Caspases; Cell Count; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Flow Cytometry; Humans; Idarubicin; Leukemia, Myeloid; Leukocyte Common Antigens; Leukocyte Count; Lymphocytes; Male; Middle Aged; Prognosis; Remission Induction | 2006 |
Early prediction of therapy response in patients with acute myeloid leukemia by nucleosomal DNA fragments.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cytarabine; Daunorubicin; DNA Fragmentation; Female; Humans; L-Lactate Dehydrogenase; Leukemia, Myeloid; Leukocytes; Male; Middle Aged; Mitoxantrone; Nucleosomes; Predictive Value of Tests; Prognosis; Thioguanine; Thymidine Kinase; Treatment Outcome | 2006 |
Double induction containing either two courses or one course of high-dose cytarabine plus mitoxantrone and postremission therapy by either autologous stem-cell transplantation or by prolonged maintenance for acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Female; Hematopoietic Stem Cell Transplantation; Humans; L-Lactate Dehydrogenase; Leukemia, Myeloid; Leukocyte Count; Male; Middle Aged; Mitoxantrone; Multivariate Analysis; Myelodysplastic Syndromes; Prognosis; Prospective Studies; Remission Induction; Risk Factors; Transplantation, Autologous; Treatment Outcome | 2006 |
Repetitive cycles of high-dose cytarabine are effective for childhood acute myeloid leukemia: long-term outcome of the children with AML treated on two consecutive trials of Tokyo Children's Cancer Study Group.
Topics: Acute Disease; Adolescent; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Down Syndrome; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Hydrocortisone; Infant; Infections; Japan; Kaplan-Meier Estimate; Leukemia, Myeloid; Male; Methotrexate; Mitoxantrone; Remission Induction; Survival Analysis; Transplantation, Autologous; Transplantation, Homologous; Treatment Outcome; Tretinoin; Vincristine | 2007 |
Non-infusional vs intravenous consolidation chemotherapy in elderly patients with acute myeloid leukemia: final results of the EORTC-GIMEMA AML-13 randomized phase III trial.
Topics: Acute Disease; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Etoposide; Female; Follow-Up Studies; Humans; Idarubicin; Infusions, Intravenous; Length of Stay; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Pancytopenia; Patient Compliance; Risk Factors | 2006 |
Less toxicity by optimizing chemotherapy, but not by addition of granulocyte colony-stimulating factor in children and adolescents with acute myeloid leukemia: results of AML-BFM 98.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cranial Irradiation; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Administration Schedule; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Infant; Infections; Leukemia, Myeloid; Male; Mitoxantrone; Neutropenia; Radiotherapy, Adjuvant; Risk Assessment; Risk Factors; Survival Analysis; Treatment Outcome | 2006 |
Pilot remission induction therapy with idarubicin, plus an intensified dose of ara-C and priming with granulocyte colony-stimulating factor for acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Pilot Projects; Remission Induction; Survival Analysis | 2007 |
Effect of priming with granulocyte-macrophage colony-stimulating factor in younger adults with newly diagnosed acute myeloid leukemia: a trial by the Acute Leukemia French Association (ALFA) Group.
Topics: Acute Disease; Adolescent; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Administration Schedule; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Neoplastic Stem Cells; Premedication; Proportional Hazards Models; Recombinant Proteins; Risk; Salvage Therapy; Stimulation, Chemical; Transplantation, Homologous; Treatment Outcome | 2007 |
Results of a multicenter phase II trial for older patients with c-Kit-positive acute myeloid leukemia (AML) and high-risk myelodysplastic syndrome (HR-MDS) using low-dose Ara-C and Imatinib.
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Cytarabine; Female; Humans; Imatinib Mesylate; Leukemia, Myeloid; Male; Myelodysplastic Syndromes; Piperazines; Pyrimidines; Stem Cell Factor; Survival Rate; Treatment Outcome | 2007 |
A comparison of low-dose cytarabine and hydroxyurea with or without all-trans retinoic acid for acute myeloid leukemia and high-risk myelodysplastic syndrome in patients not considered fit for intensive treatment.
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Hydroxyurea; Leukemia, Myeloid; Male; Middle Aged; Myelodysplastic Syndromes; Risk; Survival; Treatment Outcome; Tretinoin | 2007 |
Gemtuzumab ozogamicin with cytarabine and mitoxantrone as a third-line treatment in a poor prognosis group of adult acute myeloid leukemia patients: a single-center experience.
Topics: Acute Disease; Adult; Aged; Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Gemtuzumab; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Palliative Care; Remission Induction; Salvage Therapy; Survival Analysis | 2007 |
The quality of molecular response to chemotherapy is predictive for the outcome of AML1-ETO-positive AML and is independent of pretreatment risk factors.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Core Binding Factor Alpha 2 Subunit; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Oncogene Proteins, Fusion; Prognosis; Remission Induction; Risk Factors; RNA, Messenger; RUNX1 Translocation Partner 1 Protein; Thioguanine | 2007 |
Effect of low-dose cytarabine and aclarubicin in combination with granulocyte colony-stimulating factor priming (CAG regimen) on the outcome of elderly patients with acute myeloid leukemia.
Topics: Aclarubicin; Acute Disease; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid; Male; Middle Aged; Treatment Outcome | 2007 |
Adding low-dose gemtuzumab ozogamicin to fludarabine, Ara-C and idarubicin (MY-FLAI) may improve disease-free and overall survival in elderly patients with non-M3 acute myeloid leukaemia: results of a prospective, pilot, multi-centre trial and comparison
Topics: Acute Disease; Aged; Aged, 80 and over; Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Female; Gemtuzumab; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Neoplasm Recurrence, Local; Pilot Projects; Prospective Studies; Survival Analysis; Treatment Outcome; Vidarabine | 2007 |
Modeling of in vitro drug activity and prediction of clinical outcome in acute myeloid leukemia.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cell Survival; Cytarabine; Daunorubicin; Humans; In Vitro Techniques; Leukemia, Myeloid; Models, Biological; Nonlinear Dynamics; Prognosis; Retrospective Studies; Spectrometry, Fluorescence; Treatment Outcome; Tumor Cells, Cultured | 2007 |
Safety and efficacy of gemtuzumab ozogamicin in combination with chemotherapy for pediatric acute myeloid leukemia: a report from the Children's Oncology Group.
Topics: Acute Disease; Adolescent; Adult; Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cytarabine; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Gemtuzumab; Humans; Infant; Leukemia, Myeloid; Male; Mitoxantrone; Survival Rate | 2008 |
Contrasting benefits of two maintenance programs following identical induction in children with acute nonlymphocytic leukemia: a report from the Childrens Cancer Study Group.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Child; Cyclophosphamide; Cytarabine; Humans; Leukemia; Thioguanine; Vincristine | 1984 |
Alternating pulses of vincristine-prednisone with cytarabine-cyclophosphamide versus vincristine-prednisone in the maintenance therapy of acute lymphoblastic leukemia.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Humans; Leukemia, Lymphoid; Prednisone; Prognosis; Random Allocation; Statistics as Topic; Time Factors; Vincristine | 1984 |
Full dose versus attenuated dose daunorubicin, cytosine arabinoside, and 6-thioguanine in the treatment of acute nonlymphocytic leukemia in the elderly.
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Administration Schedule; Heart; Hemorrhage; Humans; Leukemia; Quality of Life; Random Allocation; Respiratory Distress Syndrome; Thioguanine | 1984 |
Reinduction chemotherapy for acute nonlymphocytic leukemia.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Doxorubicin; Female; Humans; Leukemia; Male; Middle Aged; Retrospective Studies; Thioguanine | 1984 |
Mitoxantrone as a single agent and in combination chemotherapy in patients with refractory acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Anthraquinones; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Clinical Trials as Topic; Cytarabine; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Prednisone; Vincristine | 1984 |
[Symposium on treatment of cancer. 1. Chemotherapy of acute leukemia in adults].
Topics: Aclarubicin; Acute Disease; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Clinical Trials as Topic; Cytarabine; Doxorubicin; Humans; Interferon Type I; Leukemia; Middle Aged; Naphthacenes | 1984 |
A randomized study of the efficacy of consolidation therapy in adult acute nonlymphocytic leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Central Nervous System Diseases; Chemical and Drug Induced Liver Injury; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Evaluation; Female; Humans; Leukemia; Male; Middle Aged; Random Allocation; Thioguanine; United States | 1984 |
In adult acute nonlymphoblastic leukaemia extended maintenance chemotherapy has no benefit.
Topics: Acute Disease; Adolescent; Adult; Cytarabine; Doxorubicin; Humans; Leukemia; Middle Aged; Podophyllotoxin; Prognosis | 1984 |
Immunotherapy maintenance in acute non-lymphocytic leukaemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Humans; Hydroxyurea; Immunotherapy; Leukemia; Middle Aged; Prednisolone; Prognosis; Random Allocation; Vincristine | 1982 |
Treatment of acute myelocytic leukemia: a study by cancer and leukemia group B.
Topics: Acute Disease; Adolescent; Adult; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Random Allocation; Time Factors | 1981 |
[Combined chemotherapy: prednisone, cytosine arabinose and vincristine in the treatment of acute non-lymphoblastic leukemia in the adult].
Topics: Acute Disease; Adolescent; Aged; Clinical Trials as Topic; Cytarabine; Drug Synergism; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Prednisone; Vincristine | 1980 |
High-dose combination chemotherapy for acute nonlymphoblastic leukemia in adults.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents; Child; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Infections; Leukemia; Middle Aged; Prednisone; Prognosis; Remission, Spontaneous; Thioguanine; Vincristine | 1981 |
Sequential studies of daunorubicin and adriamycin in acute nonlymphocytic leukemia.
Topics: Acute Disease; Adult; Age Factors; Antineoplastic Agents; Clinical Trials as Topic; Cytarabine; Daunorubicin; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Humans; Leukemia | 1981 |
Prednimustine and vincristine compared with cytosine arabinoside and thioguanine for treatment of elderly patients with acute nonlymphoblastic leukemia.
Topics: Acute Disease; Aged; Blood Cell Count; Chlorambucil; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Middle Aged; Prednimustine; Thioguanine; Vincristine | 1982 |
[The results of 2 and 1/2 years of work of the Russian Multicenter Trial on the Treatment of Acute Myeloid Leukemias in Adults].
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Humans; Leukemia, Myeloid; Male; Mercaptopurine; Remission Induction; Russia; Survival Analysis; Time Factors | 1995 |
Recombinant human glycosylated granulocyte colony-stimulating factor (rhG-CSF)-combined regimen for allogeneic bone marrow transplantation in refractory acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Glycosylation; Granulocyte Colony-Stimulating Factor; Humans; In Vitro Techniques; Leukemia, Myeloid; Male; Pilot Projects; Recombinant Proteins; Recurrence; Tumor Cells, Cultured; Whole-Body Irradiation | 1994 |
FLAG (fludarabine + high-dose cytarabine + G-CSF): an effective and tolerable protocol for the treatment of 'poor risk' acute myeloid leukemias.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Male; Middle Aged; Neoplasms, Second Primary; Vidarabine | 1994 |
New perspectives in the treatment of acute myeloid leukemia by hematopoietic growth factors.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Clinical Trials as Topic; Colony-Stimulating Factors; Cytarabine; DNA Polymerase II; Drug Screening Assays, Antitumor; Drug Synergism; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-3; Leukemia, Myeloid; Neutropenia; Randomized Controlled Trials as Topic; Survival Analysis | 1994 |
L-asparaginase may potentiate the leukemogenic effect of the epipodophyllotoxins.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Synergism; Etoposide; Humans; Infant; Karyotyping; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Neoplasms, Second Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone | 1995 |
Clinical significance of surface antigen expression in children with acute myeloid leukemia: results of study AML-BFM-87.
Topics: Acute Disease; Adolescent; Antibodies, Monoclonal; Antigens, CD; Antigens, Neoplasm; Antigens, Surface; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Child; Child, Preschool; Chromosome Aberrations; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Humans; Immunophenotyping; Infant; Leukemia, Myeloid; Neoplastic Stem Cells; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Prospective Studies; Sensitivity and Specificity; Treatment Outcome | 1995 |
A randomized placebo-controlled phase III study of granulocyte-macrophage colony-stimulating factor in adult patients (> 55 to 70 years of age) with acute myelogenous leukemia: a study of the Eastern Cooperative Oncology Group (E1490).
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Examination; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease-Free Survival; Double-Blind Method; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunologic Factors; Length of Stay; Leukemia, Myeloid; Male; Middle Aged; Neutropenia; Prospective Studies; Recombinant Proteins; Remission Induction; Survival Analysis; Treatment Outcome | 1995 |
Clinical pharmacology of cytarabine in patients with acute myeloid leukemia: a cancer and leukemia group B study.
Topics: Acute Disease; Adolescent; Adult; Aged; Cytarabine; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Treatment Outcome | 1995 |
No increase of leukemia relapse in newly diagnosed patients with acute myeloid leukemia who received granulocyte colony-stimulating factor for life-threatening infection during remission induction and consolidation therapy. Japan Adult Leukemia Study Grou
Topics: Acute Disease; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Communicable Diseases; Cytarabine; Daunorubicin; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Mercaptopurine; Prednisolone; Recombinant Proteins; Recurrence; Remission Induction; Survival Analysis; Time Factors; Vincristine | 1993 |
Wider benefits of leukodepletion of blood products.
Topics: Acute Disease; Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Blood Transfusion; Bone Marrow Transplantation; Cell Separation; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Filtration; Humans; Immunization; Leukemia, Myeloid; Leukocytes; Life Tables; Prospective Studies; Remission Induction; Treatment Outcome | 1995 |
Idarubicin, high-dose cytarabine and etoposide for remission induction in therapy-related acute myeloid leukemia.
Topics: Acute Disease; Adult; Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; Blood Transfusion; Bone Marrow Diseases; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Etoposide; Female; Gastrointestinal Diseases; Humans; Idarubicin; Leukemia, Myeloid; Leukemia, Radiation-Induced; Male; Middle Aged; Neoplasms; Prospective Studies; Radiotherapy; Remission Induction; Salvage Therapy; Treatment Outcome | 1994 |
The treatment of older adult patients with acute myeloid leukemia by triple infusion chemotherapy.
Topics: Acute Disease; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Humans; Infusions, Intravenous; Leukemia, Myeloid; Middle Aged; Remission Induction; Survival Rate | 1995 |
MDR1 RNA expression as a prognostic factor in acute myeloid leukemia: an update.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Cytarabine; Daunorubicin; Drug Resistance; Female; Follow-Up Studies; Gene Expression; Humans; Idarubicin; Leukemia, Myeloid; Male; Membrane Glycoproteins; Middle Aged; Prognosis; Remission Induction; RNA, Neoplasm; Survival Rate; Treatment Outcome | 1993 |
Autologous bone marrow transplantation with alkyl-lysophospholipid-purged marrow.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Purging; Bone Marrow Transplantation; Combined Modality Therapy; Cryopreservation; Cyclophosphamide; Cytarabine; Etoposide; Female; Hematopoietic Stem Cells; Humans; Infections; Leukemia; Life Tables; Male; Middle Aged; Neoplastic Stem Cells; Phospholipid Ethers; Salvage Therapy; Survival Analysis; Tissue Preservation; Whole-Body Irradiation | 1993 |
Comparison of survival. Chemotherapeutically treated and untreated older patient with acute myeloid leukemia.
Topics: Acute Disease; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Doxorubicin; Female; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Remission Induction; Sex Factors; Survival Rate; Thioguanine | 1994 |
[The results of a multicenter cooperative study on treating acute myeloid leukemias in adults].
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Remission Induction; Russia | 1994 |
Results of conventional-dose cytosine arabinoside and idarubicin in elderly patients with acute myeloid leukemia.
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Humans; Idarubicin; Leukemia, Erythroblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Middle Aged; Survival Analysis | 1994 |
Prognostic value of immunophenotyping in acute myeloid leukemia. Australian Leukaemia Study Group.
Topics: Acute Disease; Adolescent; Adult; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Daunorubicin; Etoposide; Follow-Up Studies; HLA-DR Antigens; Humans; Immunophenotyping; Leukemia; Middle Aged; Predictive Value of Tests; Prognosis; Survival Analysis; Time Factors | 1994 |
Intensive postremission chemotherapy in adults with acute myeloid leukemia. Cancer and Leukemia Group B.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Leukemia, Myeloid; Male; Middle Aged; Remission Induction; Survival Rate | 1994 |
High-dose mercaptopurine followed by intermediate-dose cytarabine in relapsed acute leukemia.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Drug Administration Schedule; Feasibility Studies; Female; Humans; Infusions, Intravenous; Leukemia, Myeloid; Male; Mercaptopurine; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Treatment Outcome | 1994 |
Nationwide randomized comparative study of daunorubicin and aclarubicin in combination with behenoyl cytosine arabinoside, 6-mercaptopurine, and prednisolone for previously untreated acute myeloid leukemia.
Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Male; Mercaptopurine; Middle Aged; Prednisolone; Prospective Studies; Survival Analysis | 1994 |
Oral induction and consolidation of acute myeloid leukemia with etoposide, 6-thioguanine, and idarubicin (ETI) in elderly patients: a randomized comparison with 5-day TAD. Finnish Leukemia Group.
Topics: Acute Disease; Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Idarubicin; Injections, Intravenous; Leukemia, Myeloid; Male; Remission Induction; Thioguanine | 1994 |
A randomized phase II study of low-dose cytosine arabinoside (LD-AraC) plus granulocyte-macrophage colony-stimulating factor (rhGM-CSF) in myelodysplastic syndromes (MDS) with a high risk of developing leukemia. EORTC Leukemia Cooperative Group.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Cytarabine; Dose-Response Relationship, Drug; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia; Male; Middle Aged; Myelodysplastic Syndromes; Recombinant Proteins; Risk Factors | 1994 |
Idarubicin/cytosine arabinoside and mitoxantrone/etoposide for the treatment of de novo acute myelogenous leukemia.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Recombinant Proteins; Remission Induction; Survival Analysis | 1993 |
Results of treatment with an intensive combination induction regimen containing idarubicin in children with acute myeloblastic leukemia: preliminary report of the Argentine Group for Treatment of Acute Leukemia.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Drug Administration Schedule; Etoposide; Female; Humans; Idarubicin; Infant; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Remission Induction; Survival Analysis | 1993 |
Impact of high-dose cytarabine and asparaginase intensification on childhood acute myeloid leukemia: a report from the Childrens Cancer Group.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Cytarabine; Drug Administration Schedule; Humans; Leukemia, Myeloid; Probability; Retrospective Studies; Survival Analysis | 1993 |
Autoimmune hypothyroidism and granulocyte-macrophage colony-stimulating factor.
Topics: Aclarubicin; Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Autoimmune Diseases; Cytarabine; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hypothyroidism; Iodide Peroxidase; Leukemia, Myeloid; Male; Recombinant Proteins; Thyroid Function Tests; Thyrotropin; Thyroxine; Triiodothyronine | 1993 |
Randomized study of individualized induction therapy with or without vincristine, and of maintenance-intensification therapy between 4 or 12 courses in adult acute myeloid leukemia. AML-87 Study of the Japan Adult Leukemia Study Group.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Leukemia, Myeloid; Male; Mercaptopurine; Middle Aged; Prednisolone; Prospective Studies; Remission Induction; Survival Rate; Time Factors; Vincristine | 1993 |
Randomized trials between behenoyl cytarabine and cytarabine in combination induction and consolidation therapy, and with or without ubenimex after maintenance/intensification therapy in adult acute myeloid leukemia. The Japan Leukemia Study Group.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chi-Square Distribution; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Follow-Up Studies; Humans; Leucine; Leukemia, Myeloid; Logistic Models; Male; Mercaptopurine; Middle Aged; Multivariate Analysis; Prednisolone; Prospective Studies; Remission Induction; Survival Rate; Treatment Outcome | 1996 |
[Response-oriented salvage chemotherapy with mitoxantrone, etoposide and enocitabine for previously treated acute myeloid leukemia. Tohoku Leukemia Study Group].
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Recurrence; Salvage Therapy | 1995 |
Causes of initial remission induction failure in patients with acute myeloid leukemia and myelodysplastic syndromes.
Topics: Acute Disease; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cause of Death; Cytarabine; Drug Resistance, Neoplasm; Female; Hemorrhage; Humans; Leukemia, Myeloid; Male; Middle Aged; Myelodysplastic Syndromes; Patient Selection; Remission Induction; Sepsis; Treatment Failure; Vidarabine | 1996 |
Oral idarubicin pharmacokinetics--correlation of trough level with idarubicin area under curve.
Topics: Acute Disease; Administration, Oral; Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chromatography, High Pressure Liquid; Cytarabine; Daunorubicin; Drug Administration Schedule; Humans; Idarubicin; Leukemia, Myeloid; Lymphoma, Non-Hodgkin; Metabolic Clearance Rate; Middle Aged | 1996 |
Autologous bone marrow transplantation versus intensive consolidation chemotherapy for acute myeloid leukemia in childhood. Pediatric Oncology Group.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Daunorubicin; Disease-Free Survival; Humans; Infant; Infant, Newborn; Leukemia, Myeloid; Survival Analysis; Thioguanine; Transplantation, Autologous | 1996 |
A randomized study of high-dose cytarabine in induction in acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Central Nervous System Diseases; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Etoposide; Eye Diseases; Female; Gastrointestinal Diseases; Humans; Leukemia, Myeloid; Life Tables; Male; Middle Aged; Remission Induction; Survival Analysis; Treatment Outcome | 1996 |
Therapy of untreated acute myeloid leukemia in the elderly: remission-induction using a non-cytarabine-containing regimen of mitoxantrone plus etoposide.
Topics: Acute Disease; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Drug Administration Schedule; Etoposide; Female; Humans; Intestinal Mucosa; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Quality of Life; Remission Induction; Survival Analysis; Treatment Outcome | 1996 |
Timed-sequential induction therapy improves postremission outcome in acute myeloid leukemia: a report from the Children's Cancer Group.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Daunorubicin; Dexamethasone; Disease-Free Survival; Drug Administration Schedule; Etoposide; Female; Humans; Infant; Infant, Newborn; Leukemia, Myeloid; Life Tables; Male; Prospective Studies; Remission Induction; Survival Analysis; Survival Rate; Thioguanine; Treatment Outcome | 1996 |
Combination of quinine as a potential reversing agent with mitoxantrone and cytarabine for the treatment of acute leukemias: a randomized multicenter study.
Topics: Acute Disease; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Cytarabine; Drug Resistance, Multiple; Female; Hematopoiesis; Humans; Leukemia; Male; Middle Aged; Mitoxantrone; Quinine | 1996 |
Influence of rhGM-CSF on Ara-C sensitivity of patients with acute myeloid leukemia in relapse: a flow cytometry study.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bromodeoxyuridine; Cell Cycle; Cytarabine; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Flow Cytometry; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Male; Middle Aged; Prognosis; Recombinant Proteins; S Phase | 1996 |
Intensive chemotherapy in childhood myelodysplastic syndrome. A comparison with results in acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Doxorubicin; Etoposide; Female; Humans; Infant; Leukemia, Myeloid; Leukocyte Count; Male; Myelodysplastic Syndromes; Platelet Count; Remission Induction; Thioguanine; Treatment Outcome | 1996 |
Amsacrine and continuous-infusion high-dose cytosine arabinoside as induction therapy for patients with newly-diagnosed acute myelogenous leukemia.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Life Tables; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Remission Induction; Survival Analysis; Treatment Outcome; Vincristine | 1996 |
Outcome of patients with acute myeloid leukemia who failed to respond to a single course of first-line induction therapy: a GIMEMA study of 218 unselected consecutive patients. Gruppo Italiano Malattie Ematologiche Maligne dell'Adulto.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Doxorubicin; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Prognosis; Remission Induction; Retrospective Studies; Salvage Therapy; Treatment Outcome | 1996 |
Peripheral blood stem cells mobilized from patients with acute myeloid leukaemia have different platelet repopulating abilities compared with those mobilized from patients with other diseases.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Blood Platelets; Bone Marrow; Cell Differentiation; Cell Lineage; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Hematopoietic Cell Growth Factors; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid; Lymphoma, Non-Hodgkin; Male; Megakaryocytes; Multiple Myeloma; Ovarian Neoplasms; Platelet Count; Thioguanine; Time Factors | 1996 |
High-dose cytarabine and recombinant human granulocyte colony-stimulating factor for the treatment of resistant acute myelogenous leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Female; Filgrastim; Gastrointestinal Diseases; Granulocyte Colony-Stimulating Factor; Humans; Immunologic Factors; Leukemia, Myeloid; Male; Middle Aged; Recombinant Proteins; Remission Induction; Salvage Therapy; Survival Rate; Treatment Outcome | 1996 |
Anthracycline drugs and MDR expression in human leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Aberrations; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Idarubicin; Leukemia, Myeloid; Life Tables; Male; Middle Aged; Neoplasm Proteins; Neoplastic Stem Cells; Prognosis; Remission Induction; Survival Analysis; Treatment Outcome | 1996 |
A randomized investigation of high-dose versus standard-dose cytosine arabinoside with daunorubicin in patients with previously untreated acute myeloid leukemia: a Southwest Oncology Group study.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Leukemia, Myeloid; Life Tables; Male; Middle Aged; Remission Induction; Survival Analysis; Treatment Outcome | 1996 |
[Low-dose chemotherapy].
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Humans; Leukemia, Myeloid; Myelodysplastic Syndromes; Remission Induction | 1996 |
Idarubicin, high-dose cytarabine, and etoposide for induction of remission in acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Etoposide; Humans; Idarubicin; Leukemia, Myeloid; Middle Aged; Recurrence; Remission Induction | 1996 |
Timed sequential chemotherapy for advanced acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone | 1996 |
Allogeneic vs autologous stem cell transplantation vs chemotherapy in patients with acute myeloid leukemia in first remission: the BGMT 87 study.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Male; Middle Aged; Prospective Studies; Remission Induction | 1996 |
Autologous bone marrow transplantation for patients with acute myeloblastic leukemia in relapse after autologous blood stem cell transplantation.
Topics: Acute Disease; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmustine; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Life Tables; Male; Middle Aged; Recurrence; Risk; Salvage Therapy; Transplantation Conditioning; Transplantation, Autologous; Treatment Outcome | 1996 |
Long-term survival and development of secondary malignancies in patients with acute myeloid leukemia treated with aclarubicin or daunorubicin plus cytosine arabinoside followed by intensive consolidation chemotherapy in a Danish national phase III trial.
Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Age Factors; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Follow-Up Studies; Humans; Leukemia, Myeloid; Male; Middle Aged; Neoplasms, Second Primary; Recurrence; Remission Induction; Survival Rate; Survivors | 1997 |
High-dose cytosine arabinoside and etoposide: an effective regimen without anthracyclines for refractory childhood acute non-lymphocytic leukemia.
Topics: Acute Disease; Adolescent; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Child; Child, Preschool; Contraindications; Cytarabine; Etoposide; Female; Humans; Infant; Infections; Leukemia, Myeloid; Male; Salvage Therapy; Treatment Outcome | 1997 |
High-dose mercaptopurine and intermediate-dose cytarabine during first remission of acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Infant; Leukemia, Myeloid; Male; Mercaptopurine; Treatment Outcome | 1997 |
A randomized trial of high- vs standard-dose mitoxantrone with cytarabine in elderly patients with acute myeloid leukemia.
Topics: Acute Disease; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Remission Induction; Survival Analysis | 1997 |
CD6-depleted allogeneic bone marrow transplantation for acute leukemia in first complete remission.
Topics: Acute Disease; Adult; Antibiotics, Antineoplastic; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Purging; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Female; Graft Survival; Graft vs Host Disease; Humans; Infections; Leukemia; Life Tables; Lymphocyte Depletion; Male; Middle Aged; Neoplasms, Second Primary; Remission Induction; Risk; Survival Analysis; T-Lymphocyte Subsets; Transplantation, Homologous; Treatment Outcome | 1997 |
Randomized comparison of DAT versus ADE as induction chemotherapy in children and younger adults with acute myeloid leukemia. Results of the Medical Research Council's 10th AML trial (MRC AML10). Adult and Childhood Leukaemia Working Parties of the Medica
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Humans; Hydrocortisone; Infant; Leukemia, Myeloid; Life Tables; Male; Methotrexate; Middle Aged; Myelodysplastic Syndromes; Patient Compliance; Remission Induction; Survival Analysis; Thioguanine; Treatment Outcome | 1997 |
Post-remission therapy of adult acute myeloid leukaemia: one cycle of high-dose versus standard-dose cytarabine. Leukaemia Project Group of the Swiss Group for Clinical Cancer Research (SAKK).
Topics: Acute Disease; Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Cytarabine; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Remission Induction; Survival Rate | 1997 |
[Chemotherapy schedules and bacteremia in adult patients with acute leukemia].
Topics: Acute Disease; Adolescent; Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bacteremia; Cytarabine; Daunorubicin; Drug Therapy, Combination; Etoposide; Female; Humans; Leukemia; Male; Mitoxantrone; Neutropenia; Risk Factors | 1996 |
Idarubicin and intermediate dose ARA-C followed by consolidation chemotherapy or bone marrow transplantation in relapsed or refractory acute myeloid leukemia.
Topics: Acute Disease; Adult; Agranulocytosis; Antibiotics, Antineoplastic; Bone Marrow Transplantation; Cytarabine; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Humans; Idarubicin; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Nausea; Remission Induction; Thrombocytopenia; Treatment Outcome; Vomiting | 1997 |
Outcome of a multicenter treatment program including autologous or allogeneic bone marrow transplantation for de novo acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cause of Death; Cytarabine; Disease-Free Survival; Etoposide; Female; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Myelomonocytic, Acute; Male; Middle Aged; Mitoxantrone; Probability; Remission Induction; Survival Rate; Transplantation, Autologous; Transplantation, Homologous | 1997 |
Engraftment of allogeneic hematopoietic progenitor cells with purine analog-containing chemotherapy: harnessing graft-versus-leukemia without myeloablative therapy.
Topics: Acute Disease; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Cladribine; Combined Modality Therapy; Cytarabine; Feasibility Studies; Female; Filgrastim; Graft vs Host Reaction; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Myelodysplastic Syndromes; Pilot Projects; Recombinant Proteins; Remission Induction; Salvage Therapy; Treatment Outcome; Vidarabine | 1997 |
Low-dose combination chemotherapy for acute myeloid leukemia in elderly patients: a novel approach.
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Myeloid; Male; Middle Aged | 1997 |
Phase I/II study of idarubicin given with continuous infusion fludarabine followed by continuous infusion cytarabine in children with acute leukemia: a report from the Children's Cancer Group.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Female; Humans; Idarubicin; Infant; Infusions, Intravenous; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Vidarabine | 1997 |
High risk of therapy-related leukemia after BEAM chemotherapy and autologous stem cell transplantation for previously treated lymphomas is mainly related to primary chemotherapy and not to the BEAM-transplantation procedure.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Combined Modality Therapy; Cytarabine; Dose-Response Relationship, Drug; Female; Hematopoietic Stem Cell Transplantation; Hodgkin Disease; Humans; Leukemia, Myeloid; Lymphoma, Non-Hodgkin; Male; Melphalan; Middle Aged; Myelodysplastic Syndromes; Neoplasms, Second Primary; Podophyllotoxin; Risk Factors | 1997 |
Use of recombinant GM-CSF during and after remission induction chemotherapy in patients aged 61 years and older with acute myeloid leukemia: final report of AML-11, a phase III randomized study of the Leukemia Cooperative Group of European Organisation fo
Topics: Acute Disease; Aged; Aged, 80 and over; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Male; Middle Aged; Prognosis; Prospective Studies; Recombinant Proteins; Remission Induction | 1997 |
Comparison of autologous bone marrow transplantation and intensive chemotherapy as postremission therapy in adult acute myeloid leukemia. The Groupe Ouest Est Leucémies Aiguës Myéloblastiques (GOELAM).
Topics: Acute Disease; Adolescent; Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Humans; Idarubicin; Leukemia, Myeloid; Middle Aged; Multivariate Analysis; Outcome Assessment, Health Care; Prognosis; Remission Induction | 1997 |
Multidrug resistance expression and proliferative studies in poor risk acute myeloid leukemia treated with the FLAG (G-CSF plus fludarabine and Ara-C) regimen.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bone Marrow; Cell Cycle; Cell Division; Cytarabine; Disease-Free Survival; Drug Resistance, Multiple; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid; Middle Aged; Risk Assessment; Tumor Stem Cell Assay; Vidarabine | 1995 |
A pilot study of continuous infusion Ara-C in combination with rhG-CSF in relapsed childhood acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Infusions, Intravenous; Leukemia, Myeloid; Male; Pilot Projects; Recombinant Proteins; S Phase | 1997 |
Autologous peripheral blood stem cell transplantation for acute myelogenous leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Leukocyte Count; Life Tables; Male; Middle Aged; Mitoxantrone; Neoplasm Recurrence, Local; Proportional Hazards Models; Prospective Studies; Remission Induction; Treatment Outcome | 1997 |
Mitoxantrone versus daunorubicin in induction-consolidation chemotherapy--the value of low-dose cytarabine for maintenance of remission, and an assessment of prognostic factors in acute myeloid leukemia in the elderly: final report. European Organization
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Prognosis; Remission Induction; Survival Analysis | 1998 |
Intensified induction chemotherapy with high dose cytarabine and etoposide for acute myeloid leukemia: a review and updated results of the Australian Leukemia Study Group.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Etoposide; Humans; Leukemia, Myeloid; Remission Induction | 1998 |
Cost-effectiveness and quality-of-life assessment of GM-CSF as an adjunct to intensive remission induction chemotherapy in elderly patients with acute myeloid leukemia.
Topics: Acute Disease; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cost-Benefit Analysis; Cytarabine; Daunorubicin; Drug Costs; Female; Follow-Up Studies; Granulocyte-Macrophage Colony-Stimulating Factor; Hospital Costs; Humans; Karnofsky Performance Status; Length of Stay; Leukemia, Myeloid; Male; Middle Aged; Prospective Studies; Quality of Life; Remission Induction; Survival Analysis; Treatment Outcome | 1998 |
Therapeutic options and treatment results for patients over 75 years of age with acute myeloid leukemia.
Topics: Acute Disease; Aged; Cytarabine; Female; Humans; Leukemia, Myeloid; Male; Remission Induction; Terminal Care; Treatment Outcome | 1998 |
Quality of life in adult patients with acute myeloid leukemia receiving intensive and prolonged chemotherapy -- a longitudinal study.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Longitudinal Studies; Male; Middle Aged; Mitoxantrone; Quality of Life; Thioguanine | 1998 |
A double-blind placebo-controlled trial of granulocyte colony-stimulating factor in elderly patients with previously untreated acute myeloid leukemia: a Southwest oncology group study (9031).
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Double-Blind Method; Filgrastim; Granulocyte Colony-Stimulating Factor; Hospitalization; Humans; Infection Control; Leukemia, Myeloid; Life Tables; Middle Aged; Neutropenia; Recombinant Proteins; Remission Induction; Safety; Survival Analysis; Treatment Outcome | 1998 |
Marked improvements in outcome with chemotherapy alone in paediatric acute myeloid leukemia: results of the United Kingdom Medical Research Council's 10th AML trial. MRC Childhood Leukaemia Working Party.
Topics: Acute Disease; Adolescent; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Humans; Infant; Infant, Newborn; Leukemia, Myeloid; Male; Mitoxantrone; Patient Compliance; Recurrence; Remission Induction; Survival Rate; Thioguanine; Transplantation, Autologous; Transplantation, Homologous; Treatment Outcome | 1998 |
High-dose cytarabine-containing chemotherapy with or without granulocyte colony-stimulating factor for children with acute leukemia.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Female; Fever; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Infant; Infections; Leukemia, Myeloid; Male; Neutropenia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome | 1998 |
Fludarabine, cytarabine, and G-CSF (FLAG) for the treatment of poor risk acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Cytarabine; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Male; Middle Aged; Recurrence; Retreatment; Risk Factors; Survival Rate; Transplantation, Autologous; Vidarabine | 1998 |
Expression of lung resistance protein and correlation with other drug resistance proteins and outcome in myelodysplastic syndromes.
Topics: Acute Disease; Antibiotics, Antineoplastic; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytarabine; Danazol; Disease Progression; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Gene Expression Regulation; Hematopoietic Stem Cells; Humans; Karyotyping; Leukemia, Myeloid; Leukemia, Myelomonocytic, Chronic; Life Tables; Myelodysplastic Syndromes; Neoplasm Proteins; Proto-Oncogene Proteins c-bcl-2; Quinine; Survival Analysis; Treatment Outcome; Tumor Suppressor Protein p53; Vault Ribonucleoprotein Particles | 1998 |
A new combination of carboplatin, high-dose cytarabine and cross-over mitoxantrone or idarubicin for refractory and relapsed acute myeloid leukemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cross-Over Studies; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Recurrence | 1998 |
Superiority of high-dose over intermediate-dose cytosine arabinoside in the treatment of patients with high-risk acute myeloid leukemia: results of an age-adjusted prospective randomized comparison.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Prospective Studies; Risk Factors | 1998 |
Repeated cycles of G-CSF-combined postremission chemotherapy for acute myeloid leukemia in a first complete remission: a pilot study.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Male; Mercaptopurine; Middle Aged; Pilot Projects; Prednisolone; Recombinant Proteins; Time Factors; Vincristine | 1998 |
Randomized clinical study comparing aggressive chemotherapy with or without G-CSF support for high-risk myelodysplastic syndromes or secondary acute myeloid leukaemia evolving from MDS.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cytarabine; Disease-Free Survival; Etoposide; Female; Follow-Up Studies; Gene Rearrangement; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Myelodysplastic Syndromes; Neutropenia; Recurrence; Survival Analysis; Treatment Outcome | 1998 |
Frequency of prolonged remission duration after high-dose cytarabine intensification in acute myeloid leukemia varies by cytogenetic subtype.
Topics: Acute Disease; Adolescent; Adult; Analysis of Variance; Antimetabolites, Antineoplastic; Cohort Studies; Cytarabine; Daunorubicin; Female; Humans; Karyotyping; Leukemia, Myeloid; Male; Middle Aged; Prospective Studies; Remission Induction; Treatment Outcome | 1998 |
Oral cytarabine ocfosfate in acute myeloid leukemia and non-Hodgkin's lymphoma--phase I/II studies and pharmacokinetics.
Topics: Acute Disease; Administration, Oral; Adult; Antineoplastic Agents; Arabinonucleotides; Biological Availability; Cytarabine; Cytidine Monophosphate; Diarrhea; Dose-Response Relationship, Drug; Half-Life; Humans; Infusions, Intravenous; Leukemia, Myeloid; Lymphoma, Non-Hodgkin; Metabolic Clearance Rate; Prodrugs; Regression Analysis | 1998 |
Granulocyte colony-stimulating factor shortens duration of critical neutropenia and prolongs disease-free survival after sequential high-dose cytosine arabinoside and mitoxantrone (S-HAM) salvage therapy for refractory and relapsed acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Critical Care; Cytarabine; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Granulocyte Colony-Stimulating Factor; Humans; Incidence; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Neutropenia; Opportunistic Infections; Recurrence; Salvage Therapy; Time Factors | 1998 |
Multidrug resistance-associated protein in acute myeloid leukemia: No impact on treatment outcome.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Marrow; Cell Line; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Resistance, Multiple; Etoposide; Female; Humans; Karyotyping; Leukemia, Myeloid; Male; Middle Aged; Prognosis; Remission Induction; Survival Analysis; Time Factors; Treatment Outcome; Tumor Cells, Cultured | 1997 |
Impact of in vivo administration of interleukin 3 on proliferation, differentiation, and chemosensitivity of acute myeloid leukemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Agents; Bone Marrow; Cell Division; Colony-Forming Units Assay; Cytarabine; Daunorubicin; Etoposide; Female; Hematopoietic Stem Cells; Humans; Immunophenotyping; Infusions, Intravenous; Interleukin-3; Ki-67 Antigen; Leukemia, Myeloid; Male; Middle Aged; Myelodysplastic Syndromes; Receptors, Growth Factor; Remission Induction | 1995 |
Chemotherapy compared with autologous or allogeneic bone marrow transplantation in the management of acute myeloid leukemia in first remission.
Topics: Acute Disease; Adolescent; Adult; Antimetabolites, Antineoplastic; Bone Marrow Transplantation; Cytarabine; Disease-Free Survival; Follow-Up Studies; Humans; Leukemia, Myeloid; Middle Aged; Remission Induction; Survival Analysis; Transplantation Conditioning; Transplantation, Autologous; Transplantation, Homologous | 1998 |
Time sequential chemotherapy for primary refractory or relapsed adult acute myeloid leukemia: results of the phase II Gemia protocol.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Combined Modality Therapy; Cytarabine; Diarrhea; Drug Administration Schedule; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Infections; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Neoplastic Stem Cells; Neutropenia; Remission Induction; Salvage Therapy; Treatment Outcome | 1999 |
Randomized phase II study of fludarabine + cytosine arabinoside + idarubicin +/- all-trans retinoic acid +/- granulocyte colony-stimulating factor in poor prognosis newly diagnosed acute myeloid leukemia and myelodysplastic syndrome.
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid; Middle Aged; Myelodysplastic Syndromes; Probability; Prognosis; Survival Rate; Time Factors; Tretinoin; Vidarabine | 1999 |
Prognostic implication of FLT3 and N-RAS gene mutations in acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; fms-Like Tyrosine Kinase 3; Genes, ras; Humans; Leukemia, Myeloid; Leukocyte Count; Male; Middle Aged; Mutation; Prognosis; Proto-Oncogene Proteins; Proto-Oncogenes; Receptor Protein-Tyrosine Kinases; Remission Induction; Survival Rate | 1999 |
A phase II study employing combination regimens containing KRN8602 in drug-resistant acute myeloid leukemia and acute lymphoblastic leukemia. KRN8602 Leukemia Study Group.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carubicin; Cytarabine; Drug Resistance, Neoplasm; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Treatment Failure; Vincristine | 1999 |
Estrogen receptor methylation is associated with improved survival in adult acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Bone Marrow Cells; Cytarabine; Daunorubicin; Disease-Free Survival; DNA Methylation; DNA, Neoplasm; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Neoplasm Proteins; Neoplastic Cells, Circulating; Neoplastic Stem Cells; Prognosis; Receptors, Estrogen; Regression Analysis | 1999 |
Multicenter randomized phase II trial of idarubicin vs mitoxantrone, combined with VP-16 and cytarabine for induction/consolidation therapy, followed by a feasibility study of autologous peripheral blood stem cell transplantation in elderly patients with
Topics: Acute Disease; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Double-Blind Method; Etoposide; Feasibility Studies; Female; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Pilot Projects; Transplantation, Autologous | 1999 |
Granulocyte-macrophage colony-stimulating factor (GM-CSF) to increase efficacy of intensive sequential chemotherapy with etoposide, mitoxantrone and cytarabine (EMA) in previously treated acute myeloid leukemia: a multicenter randomized placebo-controlled
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cytarabine; Disease-Free Survival; Drug Synergism; Etoposide; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoiesis; Humans; Leukemia, Myeloid; Male; Mitoxantrone; Recurrence | 1999 |
A phase III comparison of high dose ARA-C (HIDAC) versus HIDAC plus mitoxantrone in the treatment of first relapsed or refractory acute myeloid leukemia Southwest Oncology Group Study.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Prognosis; Recurrence; Treatment Outcome | 1999 |
[Results of clinical trials in the treatment of acute myeloid leukemia in adults during a 7-year period].
Topics: Acute Disease; Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Humans; Leukemia, Myeloid; Middle Aged; Time Factors; Treatment Outcome | 1999 |
The impact of karyotype on remission rates in adult patients with de novo acute myeloid leukemia receiving high-dose cytarabine-based induction chemotherapy.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Etoposide; Humans; Idarubicin; Karyotyping; Leukemia, Myeloid; Middle Aged; Multivariate Analysis; Remission Induction; Treatment Outcome | 1999 |
No beneficial effect from addition of etoposide to daunorubicin, cytarabine, and 6-mercaptopurine in individualized induction therapy of adult acute myeloid leukemia: the JALSG-AML92 study. Japan Adult Leukemia Study Group.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myeloid; Male; Mercaptopurine; Middle Aged; Prospective Studies; Remission Induction; Survival Analysis | 1999 |
Phase-II trial of idarubicin, fludarabine, cytosine arabinoside, and filgrastim (Ida-FLAG) for treatment of refractory, relapsed, and secondary AML.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemical and Drug Induced Liver Injury; Cytarabine; Female; Fever of Unknown Origin; Filgrastim; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Recombinant Proteins; Recurrence; Vidarabine | 1999 |
Parallel phase I studies of daunorubicin given with cytarabine and etoposide with or without the multidrug resistance modulator PSC-833 in previously untreated patients 60 years of age or older with acute myeloid leukemia: results of cancer and leukemia g
Topics: Acute Disease; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cyclosporins; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Leukemia, Myeloid; Male; Middle Aged | 1999 |
Intensive chemotherapy with idarubicin, ara-C, etoposide, and m-AMSA followed by immunotherapy with interleukin-2 for myelodysplastic syndromes and high-risk Acute Myeloid Leukemia (AML).
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Etoposide; Female; Humans; Idarubicin; Immunotherapy; Interleukin-2; Leukemia, Myeloid; Male; Middle Aged; Myelodysplastic Syndromes; Prospective Studies; Survival Rate | 2000 |
Granulocyte colony-stimulating factor after intensive consolidation chemotherapy in acute myeloid leukemia: results of a randomized trial of the Groupe Ouest-Est Leucémies Aigues Myeloblastiques.
Topics: Acute Disease; Adolescent; Adult; Amsacrine; Anti-Bacterial Agents; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Hospitalization; Humans; Length of Stay; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Neutropenia; Recombinant Proteins; Remission Induction; Treatment Outcome | 2000 |
Autologous stem cell transplantation for acute myeloid leukemia in first remission.
Topics: Acute Disease; Adolescent; Adult; Aged; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cytapheresis; Cytarabine; Cytogenetics; Disease-Free Survival; Etoposide; Graft Survival; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Leukocyte Count; Middle Aged; Recurrence; Survival Rate; Transplantation, Autologous | 2000 |
Cyclophosphamide, ara-C and topotecan (CAT) for patients with refractory or relapsed acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Humans; Leukemia; Middle Aged; Recurrence; Topotecan; Treatment Outcome | 2000 |
Phase II evaluation of a high-dose mitoxantrone based induction regimen in untreated adults with acute myeloid leukemia.
Topics: Actuarial Analysis; Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Conjunctivitis; Cytarabine; Disease-Free Survival; Etoposide; Female; Gastrointestinal Diseases; Humans; Hyperbilirubinemia; Leukemia, Myeloid; Male; Methylprednisolone; Middle Aged; Mitoxantrone; Remission Induction; Risk; Stomatitis; Stroke Volume; Survival Analysis; Survival Rate; Treatment Outcome; Tretinoin; Ventricular Dysfunction, Left | 2000 |
Prognostic value of p53 gene mutations and the product expression in de novo acute myeloid leukemia.
Topics: Acute Disease; Adult; Aged; Amino Acid Substitution; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; DNA Mutational Analysis; Etoposide; Female; Gene Deletion; Genes, p53; Humans; Japan; Leukemia, Myeloid; Life Tables; Male; Mercaptopurine; Middle Aged; Mutation; Mutation, Missense; Neoplasm Proteins; Prednisolone; Prognosis; Regulatory Sequences, Nucleic Acid; Single-Blind Method; Survival Analysis; Tumor Suppressor Protein p53; Vincristine | 2000 |
Low-dose cytarabine maintenance therapy vs observation after remission induction in advanced acute myeloid leukemia: an Eastern Cooperative Oncology Group Trial (E5483).
Topics: Acute Disease; Adult; Aged; Antimetabolites, Antineoplastic; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Prospective Studies; Recurrence; Remission Induction | 2000 |
Karyotypic analysis predicts outcome of preremission and postremission therapy in adult acute myeloid leukemia: a Southwest Oncology Group/Eastern Cooperative Oncology Group Study.
Topics: Acute Disease; Adolescent; Adult; Aneuploidy; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Chromosome Aberrations; Chromosomes, Human; Combined Modality Therapy; Cytarabine; Female; Humans; Idarubicin; Karyotyping; Leukemia, Myeloid; Life Tables; Male; Middle Aged; Remission Induction; Risk; Survival Analysis; Translocation, Genetic; Transplantation, Autologous; Transplantation, Homologous; Treatment Outcome | 2000 |
A multicentre, open, non-comparative phase II study of a combination of fludarabine phosphate, cytarabine and granulocyte colony-stimulating factor in relapsed and refractory acute myeloid leukaemia and de novo refractory anaemia with excess of blasts in
Topics: Acute Disease; Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Male; Middle Aged; Prospective Studies; Recurrence; Vidarabine | 2001 |
Patients with de novo acute myeloid leukaemia and complex karyotype aberrations show a poor prognosis despite intensive treatment: a study of 90 patients.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Chromosome Aberrations; Cytarabine; Cytogenetic Analysis; Daunorubicin; Disease-Free Survival; Female; Follow-Up Studies; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Prognosis; Remission Induction; Thioguanine | 2001 |
Phase I/II study of the P-glycoprotein modulator PSC 833 in patients with acute myeloid leukemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Cyclosporins; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Infusions, Intravenous; Leukemia, Myeloid; Male; Middle Aged; Risk Factors; Treatment Outcome | 2001 |
The association of topotecan and cytarabine in the treatment of secondary or relapsed acute myeloid leukemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Myeloid; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms, Second Primary; Recurrence; Therapeutic Equivalency; Topotecan; Treatment Outcome | 2001 |
Mitoxantrone, etoposide, carboplatinum and ara-C combination therapy (MECA) in refractory and relapsed acute leukemia.
Topics: Actuarial Analysis; Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cytarabine; Disease-Free Survival; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Male; Middle Aged; Mitoxantrone; Recurrence; Risk Factors; Salvage Therapy; Treatment Outcome | 2000 |
Comparison of 'sequential' versus 'standard' chemotherapy as re-induction treatment, with or without cyclosporine, in refractory/relapsed acute myeloid leukaemia (AML): results of the UK Medical Research Council AML-R trial.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclosporine; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Administration Schedule; Etoposide; Female; Humans; Immunosuppressive Agents; Leukemia, Myeloid; Male; Middle Aged; Remission Induction | 2001 |
Treatment of "poor risk" acute myeloid leukemia with fludarabine, cytarabine and G-CSF (flag regimen): a single center study.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Cytarabine; Disease-Free Survival; Female; Granulocyte Colony-Stimulating Factor; Humans; Infections; Leukemia, Myeloid; Male; Middle Aged; Remission Induction; Salvage Therapy; Sex Factors; Vidarabine | 2001 |
First line therapy with fludarabine combinations in 42 patients with either post myelodysplastic syndrome or therapy related acute myeloid leukaemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Male; Middle Aged; Myelodysplastic Syndromes; Neoplasms, Second Primary; Remission Induction; Survival Rate; Vidarabine | 2001 |
Fludarabine, arabinosyl cytosine and idarubicin (FLAI) for remission induction in poor-risk acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Cytarabine; Disease-Free Survival; Female; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Pancytopenia; Pilot Projects; Remission Induction; Salvage Therapy; Survival Analysis; Survival Rate; Vidarabine | 2001 |
Postremission therapy in older patients with de novo acute myeloid leukemia: a randomized trial comparing mitoxantrone and intermediate-dose cytarabine with standard-dose cytarabine.
Topics: Actuarial Analysis; Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Dose-Response Relationship, Drug; Double-Blind Method; Follow-Up Studies; Humans; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Remission Induction; Survival Rate; Time Factors; Treatment Outcome | 2001 |
Efficacy of fludarabine, intermittent sequential high-dose cytosine arabinoside, and mitoxantrone (FIS-HAM) salvage therapy in highly resistant acute leukemias.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Drug Administration Schedule; Drug Resistance; Humans; Leukemia; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Salvage Therapy; Therapeutic Equivalency; Treatment Outcome; Vidarabine | 2001 |
Double reinforcement with fludarabine/high-dose cytarabine enhances the impact of autologous stem cell transplantation in acute myeloid leukemia patients.
Topics: Actuarial Analysis; Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Purging; Cytarabine; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Leukemia, Myeloid; Male; Mitoxantrone; Remission Induction; Survival Analysis; Transplantation, Autologous; Treatment Outcome; Vidarabine | 2001 |
Effects of glycosylated recombinant human granulocyte colony-stimulating factor after high-dose cytarabine-based induction chemotherapy for adult acute myeloid leukaemia.
Topics: Acute Disease; Adjuvants, Immunologic; Adult; Cost-Benefit Analysis; Cytarabine; Female; Glycosylation; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Lenograstim; Leukemia, Myeloid; Male; Middle Aged; Recombinant Proteins; Survival Rate | 2001 |
[Comparison of the effectiveness of idarubicin (Zavedos) and mitoxantrone (Refador) in induction therapy of acute myeloid leukemia in elderly patients (55-75) (a prospective multicenter randomized study conducted 1998-2000].
Topics: Acute Disease; Aged; Antineoplastic Agents; Cytarabine; Female; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Prospective Studies; Remission Induction; Survival Rate | 2001 |
Phase I trial with escalating doses of idarubicin and multidrug resistance reversal by short-course cyclosporin A, sequential high-dose cytosine arabinoside, and granulocyte colony-stimulating factor for adult patients with refractory acute leukemia.
Topics: Acute Disease; Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cyclosporine; Cytarabine; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia; Male; Maximum Tolerated Dose; Middle Aged; Salvage Therapy; Treatment Outcome | 2002 |
Granulocyte-macrophage colony-stimulating factor (GM-CSF) priming with successive concomitant low-dose Ara-C for elderly patients with secondary/refractory acute myeloid leukemia or advanced myelodysplastic syndrome.
Topics: Acute Disease; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Male; Middle Aged; Neutropenia; Survival Rate; Thrombocytopenia; Treatment Outcome | 2002 |
Effect of glutathione S-transferases on the survival of patients with acute myeloid leukaemia.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Alleles; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Cytarabine; Doxorubicin; Female; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Isoenzymes; Leukemia, Myeloid; Male; Middle Aged; Survival Analysis; Survival Rate; Treatment Outcome | 2002 |
Dose-finding study of valspodar (PSC 833) with daunorubicin and cytarabine to reverse multidrug resistance in elderly patients with previously untreated acute myeloid leukemia.
Topics: Acute Disease; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cohort Studies; Cyclosporins; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Edema; Female; Fever; Humans; Hypokalemia; Leukemia, Myeloid; Male; Maximum Tolerated Dose; Middle Aged; Nausea; Neoplasm Proteins; Remission Induction; Survival Analysis; Survival Rate; Treatment Outcome | 2000 |
All trans retinoic acid in combination with intermediate-dose cytarabine and idarubicin in patients with relapsed or refractory non promyelocytic acute myeloid leukemia: a phase II randomized trial.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Remission Induction; Salvage Therapy; Survival Analysis; Therapeutic Equivalency; Treatment Outcome; Tretinoin | 2002 |
Intermediate-dose cytarabine treatment delivered at moderate infusion rates for de novo acute myeloid leukemia-results of a phase I-II study.
Topics: Acute Disease; Adolescent; Adult; Algorithms; Cytarabine; Drug Administration Schedule; Female; Humans; Infusions, Parenteral; Leukemia, Myeloid; Male; Middle Aged; Remission Induction; Stem Cell Transplantation; Survival Analysis; Transplantation, Homologous; Treatment Outcome | 2002 |
Timed sequential chemotherapy with concomitant granulocyte colony-stimulating factor for high-risk acute myelogenous leukemia: a single arm clinical trial.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cell Count; Cytarabine; Drug Administration Schedule; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Neutrophils; Platelet Count; Risk Factors; Survival Rate; Time Factors; Treatment Outcome | 2002 |
Gemtuzumab ozogamicin with or without interleukin 11 in patients 65 years of age or older with untreated acute myeloid leukemia and high-risk myelodysplastic syndrome: comparison with idarubicin plus continuous-infusion, high-dose cytosine arabinoside.
Topics: Acute Disease; Aged; Aged, 80 and over; Aminoglycosides; Anemia, Refractory, with Excess of Blasts; Anti-Bacterial Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bayes Theorem; Cytarabine; Drug Therapy, Combination; Gemtuzumab; Humans; Idarubicin; Immunotoxins; Infusions, Parenteral; Interleukin-11; Leukemia, Myeloid; Myelodysplastic Syndromes; Remission Induction; Survival Analysis; Therapeutic Equivalency | 2002 |
Flexible low-intensity combination chemotherapy for elderly patients with acute myeloid leukemia.
Topics: Acute Disease; Aged; Aged, 80 and over; Algorithms; Antineoplastic Combined Chemotherapy Protocols; Cell Death; Cytarabine; Etoposide; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Survival Analysis; Treatment Outcome | 2002 |
The effect of thioguanine on a combination of daunorubicine, cytarabine and prednisone in the treatment of acute leukaemia in adults. The Finnish Leukaemia Group.
Topics: Acute Disease; Adolescent; Adult; Aged; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Middle Aged; Prednisone; Prognosis; Remission, Spontaneous; Thioguanine | 1979 |
The immunotherapy of acute myelogenous leukaemia using intravenous BCG.
Topics: Acute Disease; Adolescent; Adult; Aged; BCG Vaccine; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Injections, Intravenous; Leukemia, Myeloid; Middle Aged; Remission, Spontaneous; Skin Tests | 1977 |
Randomized clinical trial of cystosine arabinoside and 6-thioguanine in remission induction and consolidation of adult nonlymphocytic acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Bone Marrow; Clinical Trials as Topic; Cytarabine; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Middle Aged; Remission, Spontaneous; Thioguanine | 1977 |
[Acute viral hepatitis. Its treatment with cytosine arabinoside].
Topics: Acute Disease; Adult; Clinical Trials as Topic; Cytarabine; Drug Evaluation; Hepatitis, Viral, Human; Humans; Injections, Intramuscular; Male | 1977 |
Increased survival in childhood acute nonlymphocytic leukemia after treatment with prednisone, cytosine arabinoside, 6-thioguanine, cyclophosphamide, and oncovin (PATCO) combination chemotherapy.
Topics: Acute Disease; Adolescent; Antineoplastic Agents; Child; Child, Preschool; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia; Leukocyte Count; Male; Prednisone; Prognosis; Remission, Spontaneous; Thioguanine; Vincristine | 1978 |
Interhospital differences in the treatment of acute leukaemia in adults. The Finnish Leukaemia Group.
Topics: Acute Disease; Adult; Aged; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Finland; Humans; Leukemia; Leukemia, Myeloid, Acute; Middle Aged; Prednisone; Prognosis; Remission, Spontaneous | 1979 |
Refractory anemia with excess of blast cells: prognostic factors and effect of treatment with androgens or cytosine arabinoside. Results of a prospective trial in 58 patients. Cooperative Group for the Study of Aplastic and Refractory Anemias.
Topics: Acute Disease; Adult; Aged; Anemia, Aplastic; Bone Marrow; Clinical Trials as Topic; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged; Preleukemia; Prognosis; Testosterone Congeners | 1979 |
Intensification of remission induction therapy for acute nonlymphocytic leukemia (ANLL). I. Response and toxicity in four different regimens.
Topics: Acute Disease; Age Factors; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Ifosfamide; Leukemia; Methods; Middle Aged; Thioguanine; Vincristine | 1979 |
Chemotherapy of acute leukemia: a comparison of vincristine, cytarabine, and prednisone alone and in combination with cyclophosphamide or daunorubicin.
Topics: Acute Disease; Adult; Aged; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Humans; Leukemia; Male; Middle Aged; Prednisone; Remission, Spontaneous; Time Factors; Vincristine | 1978 |
Early consolidation chemotherapy for adults with acute leukemia in remission.
Topics: Acute Disease; Adolescent; Adult; Anti-Bacterial Agents; Antineoplastic Agents; Bacterial Infections; Cytarabine; Enterocolitis, Pseudomembranous; Female; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Necrosis; Prednisone; Remission, Spontaneous; Vincristine | 1976 |
A study of intermittent alternating drug program reinduction therapy on the frequency and duration of response in adult acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Agents; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Drug Administration Schedule; Female; Humans; Infant; Infant, Newborn; Leukemia; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Remission, Spontaneous; Vincristine | 1976 |
Study of cytosine arabinoside (NSC-63878) synchronization plus vincristine (NSC-67574), prednisone (NSC-10023), and L-asparaginase (NSC-109229) for remission induction in advanced acute leukemia in children.
Topics: Acute Disease; Adolescent; Antineoplastic Agents; Asparaginase; Cell Division; Cells, Cultured; Child; Cytarabine; DNA, Neoplasm; Drug Therapy, Combination; Humans; Leukemia; Prednisone; Remission, Spontaneous; Vincristine | 1976 |
The current status of the treatment of childhood acute lymphoblastic leukemia.
Topics: Acute Disease; Age Factors; Animals; Antineoplastic Agents; Asparaginase; Central Nervous System Diseases; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Infant; Leukemia, Lymphoid; Mercaptopurine; Methotrexate; Prednisone; Remission, Spontaneous; Vincristine | 1976 |
Progress in the treatment of adults with acute leukemia: review of regimens containing cytarabine studied by the Southwest Oncology Group.
Topics: Acute Disease; Adult; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Humans; Leukemia; Leukemia, Lymphoid; Middle Aged; Prednisone; Vincristine | 1976 |
Randomized clinical comparison of daunorubicin (NSC-82151) alone with a combination of daunorubicin, cytosine arabinoside (NSC-63878), 6-thioguanine (NSC-752), and pyrimethamine (NSC-3061) for the treatment of acute nonlymphocytic leukemia.
Topics: Acute Disease; Aged; Antineoplastic Agents; Bone Marrow; Central Nervous System Diseases; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Guanazole; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Meninges; Middle Aged; Pyrimethamine; Remission, Spontaneous; Skin Tests; Thioguanine | 1976 |
[Clinical use of cytosine arabinoside in infancy. I. Cytosine arabinoside in the treatment of acute leukosis].
Topics: Acute Disease; Adolescent; Child; Child, Preschool; Clinical Trials as Topic; Cytarabine; Drug Evaluation; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male | 1975 |
[Results of therapy in acute leukemia in adults. Comparison of different combinations of cytotoxic drugs].
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Aminosalicylic Acids; Antineoplastic Agents; Cytarabine; Drug Combinations; Esterases; Histocytochemistry; Humans; Leukemia; Mercaptopurine; Methotrexate; Middle Aged; Peroxidases; Prednisone; Prognosis; Remission, Spontaneous; Vincristine | 1975 |
Current strategies for treatment of acute myeloid leukemia at St Jude Children's Research Hospital.
Topics: 2-Chloroadenosine; Acute Disease; Adolescent; Adult; Amsacrine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Child; Child, Preschool; Cladribine; Cytarabine; Daunorubicin; Deoxyadenosines; Etoposide; Humans; Infant; Leukemia, Myeloid, Acute; Remission Induction | 1992 |
Treatment of acute myeloid leukemia in the elderly with low-dose cytarabine, hydroxyurea, and calcitriol.
Topics: Acute Disease; Administration, Oral; Age Factors; Aged; Aged, 80 and over; Bone Marrow; Calcitriol; Cytarabine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Hydroxyurea; Infusions, Intravenous; Leukemia, Myeloid; Middle Aged | 1992 |
Intensive induction chemotherapy in elderly patients. The BGMT Group.
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Idarubicin; Leukemia, Myeloid; Middle Aged | 1992 |
The selective use of AMSA following high-dose cytarabine in patients with acute myeloid leukaemia in relapse: a Leukemia Intergroup study.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Remission Induction; Treatment Outcome | 1992 |
Relationship of [3H]Ara-C incorporation and response to therapy with high-dose Ara-C in AML patients: a Leukemia Intergroup study.
Topics: Acute Disease; Bone Marrow; Bromodeoxyuridine; Cytarabine; DNA, Neoplasm; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid; S Phase; Tritium; Tumor Cells, Cultured | 1992 |
High-dose cytosine arabinoside remission induction for acute myelogenous leukemia: comparison of two regimens of remission maintenance.
Topics: Acute Disease; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid; Middle Aged; Prednisone; Survival Analysis; Tretinoin | 1992 |
[The therapeutic results in acute myeloid leukemias in elderly patients].
Topics: Acute Disease; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Resistance; Female; Humans; Leukemia, Myeloid; Male; Mercaptopurine; Middle Aged; Remission Induction; Time Factors | 1992 |
Treatment of myelodysplastic syndromes (MDS) and high leukaemic risk with low-dose cytosine arabinoside (LD-AraC) plus granulocyte-macrophage colony-stimulating factor (rh GM-CSF). The EORTC Leukaemia Group.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anemia, Refractory, with Excess of Blasts; Bone Marrow; Cytarabine; Drug Administration Schedule; Drug Therapy, Combination; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Injections, Subcutaneous; Leukemia; Male; Middle Aged; Risk Factors; Survival Rate | 1992 |
Maintenance with low-dose cytarabine for acute myeloid leukemia in complete remission.
Topics: Acute Disease; Aged; Aged, 80 and over; Cytarabine; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Leukemia, Myeloid; Male; Middle Aged; Pilot Projects; Remission Induction | 1992 |
Low-dose cytosine arabinoside for treating hypocellular acute leukemia in the elderly.
Topics: Acute Disease; Age Factors; Aged; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Injections, Subcutaneous; Leukemia; Male; Middle Aged; Time Factors | 1992 |
Varying intensity of postremission therapy in acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Follow-Up Studies; Heparin; Humans; Leukemia, Myeloid; Middle Aged; Remission Induction; Thioguanine | 1992 |
Escalating the intensity of post-remission therapy improves the outcome in acute myeloid leukemia: the ECOG experience. The Eastern Cooperative Oncology Group.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Clinical Protocols; Combined Modality Therapy; Cytarabine; Doxorubicin; Drug Administration Schedule; Humans; Leukemia, Myeloid; Middle Aged; Pilot Projects; Remission Induction; Survival Analysis; Thioguanine; Transplantation, Autologous | 1992 |
Autologous bone marrow transplantation vs intensive chemotherapy in first complete remission: interim results of GOELAM study in AML.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Drug Administration Schedule; France; Humans; Idarubicin; Leukemia, Myeloid; Middle Aged; Remission Induction; Survival Analysis; Transplantation, Autologous | 1992 |
The impact of early intensive therapy on event-free survival (EFS) in children with acute myeloid leukemia (AML).
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Daunorubicin; Drug Administration Schedule; Humans; Infant; Leukemia, Myeloid; Prognosis; Remission Induction; Survival Rate; Thioguanine | 1992 |
Therapeutic strategies for postremission treatment in childhood acute myeloid leukemia (AML). The AIEOP experience 1987-1991.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Daunorubicin; Female; Humans; Infant; Italy; Leukemia, Myeloid; Male; Pilot Projects; Random Allocation; Recurrence; Remission Induction | 1992 |
Intensive chemotherapy with or without additional bone marrow transplantation in paediatric AML: progress report on the MRC AML 10 trial. Medical Research Council Working Party on Childhood Leukaemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Daunorubicin; Etoposide; Humans; Infant; Leukemia, Myeloid; Recurrence; Remission Induction; Thioguanine; United Kingdom | 1992 |
Intensive post-remission therapy with Ara-C in adults with acute myeloid leukemia: initial results of a CALGB phase III trial. The Cancer and Leukemia Group B.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Remission Induction | 1992 |
Longterm effects of prolonged maintenance and of very early intensification chemotherapy in AML: data from AMLCG.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Humans; Leukemia, Myeloid; Middle Aged; Recurrence; Remission Induction; Thioguanine | 1992 |
Intensive consolidation chemotherapy versus standard consolidation maintenance in acute myelogenous leukemia (AML) in first remission. An EORTC/GIMEMA phase III trial (AML8 B). The EORTC Leukemia Cooperative Group and the GIMEMA Group.
Topics: Actuarial Analysis; Acute Disease; Adolescent; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Daunorubicin; Drug Administration Schedule; Follow-Up Studies; Humans; Italy; Leukemia, Myeloid; Middle Aged; Remission Induction; Thioguanine | 1992 |
Randomized study of individualized induction therapy with or without VCR, and of maintenance of 4 or 12 courses in adult AML: JALSG-AML87. Japan Adult Leukemia Study Group (JALSG).
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Humans; Japan; Leukemia, Myeloid; Male; Mercaptopurine; Middle Aged; Prednisolone; Remission Induction; Vincristine | 1992 |
Risk factors for high-dose cytarabine neurotoxicity: an analysis of a cancer and leukemia group B trial in patients with acute myeloid leukemia.
Topics: Acute Disease; Adult; Age Factors; Aged; Alkaline Phosphatase; Aspartate Aminotransferases; Creatinine; Cytarabine; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Nervous System Diseases; Risk Factors | 1992 |
Improved cure rate by very early intensification combined with prolonged maintenance chemotherapy in patients with acute myeloid leukemia: data from the AML Cooperative Group.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid; Remission Induction; Thioguanine | 1991 |
Double intensive consolidation chemotherapy in adult acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Child; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Prognosis; Survival Analysis | 1991 |
New agents in the treatment of acute myeloid leukemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cytarabine; Daunorubicin; Drug Evaluation; Etoposide; Humans; Idarubicin; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Remission Induction; Tretinoin | 1991 |
In vitro and in vivo effects of rh GM-CSF in acute myeloid leukemia (AML).
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cell Division; Cytarabine; Daunorubicin; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cells; Humans; Infusions, Intravenous; Leukemia, Myeloid; Mitoxantrone; Recombinant Proteins; Thioguanine; Tumor Stem Cell Assay | 1991 |
A comparative study of two different doses of cytarabine for acute myeloid leukemia: a phase III trial of Cancer and Leukemia Group B.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Leukemia, Myeloid; Male; Middle Aged; Prednisone; Remission Induction; Thioguanine; Time Factors; Vincristine | 1991 |
Simultaneous administration of granulocyte-macrophage colony-stimulating factor and cytosine arabinoside for the treatment of relapsed acute myeloid leukemia.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Drug Evaluation; Enzyme-Linked Immunosorbent Assay; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Infusions, Intravenous; Leukemia, Myeloid; Leukocyte Count; Male; Middle Aged; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor; Recombinant Proteins; S Phase | 1991 |
Five-day 4'-(9-acridinylamino)methanesulphon-m-anisidide and intermediate-dose cytosine arabinoside in high-risk relapsing or refractory acute myeloid leukemia.
Topics: Acute Disease; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid; Male; Middle Aged | 1991 |
Value of maintenance therapy with chemotherapy or interferon during remission of acute myeloid leukaemia.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Humans; Interferon-alpha; Leukemia, Myeloid; Male; Prospective Studies; Remission Induction; Thioguanine | 1991 |
Acute myeloid leukaemia: results of the New Zealand AML-1 study. The Leukaemia Study Group of the New Zealand Society for Haematology.
Topics: Acute Disease; Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Follow-Up Studies; Humans; Leukemia, Myeloid; Male; Middle Aged; New Zealand; Remission Induction; Survival Rate | 1991 |
Mitoxantrone and cytarabine versus daunorubicin and cytarabine in previously untreated patients with acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Prospective Studies; Remission Induction | 1991 |
Double intensive consolidation chemotherapy in adult acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Amsacrine; Analysis of Variance; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Pilot Projects; Proportional Hazards Models; Remission Induction | 1991 |
[A trial of the use of high doses of cytosar with autologous bone marrow protection in acute leukemias].
Topics: Acute Disease; Adolescent; Adult; Blood Cells; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Female; Humans; Leukemia; Male; Recurrence; Remission Induction; Time Factors; Transplantation, Autologous | 1990 |
Induction failures in childhood acute nonlymphocytic leukemia: etoposide/5-azacytidine for cases refractory to daunorubicin/cytarabine.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Child; Clinical Trials as Topic; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia; Male | 1986 |
[Intermediate-dose cytosine arabinoside therapy in refractory acute leukemia].
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cytarabine; Doxorubicin; Drug Resistance; Female; Humans; Leukemia; Male; Middle Aged; Multicenter Studies as Topic; Remission Induction; Vincristine | 1989 |
Advanced pancreatic cancer: a phase I-II trial of cisplatin, high-dose cytarabine, and caffeine.
Topics: Acute Disease; Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Caffeine; Cisplatin; Clinical Trials as Topic; Cytarabine; Drug Administration Schedule; Drug Evaluation; Female; Humans; Male; Middle Aged; Pancreatic Neoplasms; Time Factors | 1989 |
[Value of high-dose cytosine-arabinoside in the treatment of resistant acute leukemia].
Topics: Acute Disease; Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Cytarabine; Drug Resistance; Humans; Infusions, Intravenous; Leukemia; Middle Aged; Neoplasm Recurrence, Local | 1987 |
[A study of B-triple V (behenoyl-ara C, etoposide, vincristine, vinblastine) in acute leukemia].
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Etoposide; Female; Humans; Leukemia; Male; Middle Aged; Vinblastine; Vincristine | 1988 |
The role of mitozantrone in the treatment of acute leukaemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Clinical Trials as Topic; Combined Modality Therapy; Cytarabine; Humans; Leukemia; Mitoxantrone | 1987 |
High-dose cytarabine and total body irradiation with or without cyclophosphamide as a preparative regimen for marrow transplantation for acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Humans; Immunosuppression Therapy; Infant; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid | 1988 |
Maintenance chemotherapy prolongs remission duration in adult acute nonlymphocytic leukemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Administration Schedule; Follow-Up Studies; Humans; Leukemia; Thioguanine | 1988 |
Intensive postremission therapy in adults with acute nonlymphocytic leukemia using various dose schedules of ara-C: a progress report from the CALGB. Cancer and Leukemia Group B.
Topics: Acute Disease; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Evaluation; Humans; Leukemia; Middle Aged; Prognosis | 1987 |
Treatment of childhood acute nonlymphocytic leukemia with individually scheduled high doses of cytarabine: preliminary results of study ANLL-82 of the Dutch Childhood Leukemia Study Group (DCLSG).
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Clinical Trials as Topic; Cytarabine; Doxorubicin; Drug Administration Schedule; Female; Humans; Leukemia; Male; Netherlands; Prednisolone; Vincristine | 1987 |
[Treatment of acute nonlymphoblastic leukemia in childhood: results of protocol ANLL-827 and ANLL-861 studies. Children's Cancer and Leukemia Study Group].
Topics: Acute Disease; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Combinations; Humans; Leukemia; Prednisone; Remission Induction; Vincristine | 1987 |
Intensive maintenance therapy improves survival in adult acute nonlymphocytic leukemia: an eight-year follow-up.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Central Nervous System Diseases; Cytarabine; Evaluation Studies as Topic; Female; Follow-Up Studies; Humans; Immunotherapy; Leukemia; Male; Middle Aged; Neuraminidase; Remission Induction; Splenectomy; Thioguanine | 1988 |
[A phase III study of BHAC-MMP (behenoyl-ara-C, mitoxantrone, 6-mercaptopurine prednisolone) in acute leukemia. Hanshin Cooperative Study Group of Hematological Disorders].
Topics: Acute Disease; Adolescent; Adult; Aged; Anthraquinones; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Female; Humans; Leukemia; Leukemia, Lymphoid; Male; Mercaptopurine; Middle Aged; Mitoxantrone; Prednisolone | 1986 |
[Mitoxantrone as combination chemotherapy in patients with acute leukemia. Tokai Blood Cancer Study Group].
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Clinical Trials as Topic; Cytarabine; Female; Humans; Leukemia; Male; Mercaptopurine; Middle Aged; Mitoxantrone; Prednisolone; Vincristine | 1986 |
A new regimen of amsacrine with high-dose cytarabine is safe and effective therapy for acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Clinical Trials as Topic; Cytarabine; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged | 1987 |
Comparison of three remission induction regimens and two postinduction strategies for the treatment of acute nonlymphocytic leukemia: a cancer and leukemia group B study.
Topics: Acute Disease; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Humans; Leukemia; Prognosis; Random Allocation; Remission Induction; Research Design; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination | 1987 |
A strategy for evaluation of new treatments in untreated patients: application to a clinical trial of AMSA for acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Doxorubicin; Humans; Leukemia; Middle Aged; Prednisone; Prognosis; Time Factors; Vincristine | 1987 |
Effect of amsacrine on ara-CTP cellular pharmacology in human leukemia cells during high-dose cytarabine therapy.
Topics: Acute Disease; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cells, Cultured; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged | 1987 |
Growth response of residual leukemia after initial drug therapy.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cytarabine; Daunorubicin; Humans; Leukemia; Middle Aged | 1986 |
High rate of long-term survival in adult acute leukemia following ten-day chemotherapy (OAP) induction. Maintenance with chemotherapy or chemotherapy plus BCG vaccine.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Clinical Trials as Topic; Cytarabine; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisone; Random Allocation; Sex Factors; Time Factors; Vincristine | 1985 |
Sequential studies on the role of mitoxantrone in the treatment of acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Agranulocytosis; Anthraquinones; Antineoplastic Agents; Bone Marrow Transplantation; Clinical Trials as Topic; Cytarabine; Female; Heart; Humans; Leukemia; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Nausea; Stroke Volume; Vomiting | 1985 |
High-dose cytosine arabinoside therapy with and without anthracycline antibiotics for remission reinduction of acute nonlymphoblastic leukemia.
Topics: Acute Disease; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Blood Cells; Bone Marrow; Clinical Trials as Topic; Cytarabine; Daunorubicin; Doxorubicin; Humans; Leukemia; Naphthacenes; Time Factors | 1985 |
[High-dose cytosine arabinoside in acute leukemia: a cooperative study].
Topics: Acute Disease; Adolescent; Adult; Child; Clinical Trials as Topic; Cytarabine; Drug Resistance; Female; Humans; Leukemia; Male; Middle Aged | 1985 |
Treatment of leukemia with low dose Ara-C: a study of 159 cases.
Topics: Acute Disease; Aged; Clinical Trials as Topic; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia; Leukemia, Lymphoid; Middle Aged | 1985 |
The epipodophyllotoxin VP16-213 in combination chemotherapy for adults with acute nonlymphoblastic leukaemia.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Doxorubicin; Etoposide; Humans; Leukemia; Podophyllotoxin; Thioguanine | 1985 |
A therapeutic trial with low-dose cytarabine in myelodysplastic syndromes and acute leukemia.
Topics: Acute Disease; Aged; Bone Marrow Diseases; Clinical Trials as Topic; Cytarabine; Drug Administration Schedule; Humans; Leukemia; Middle Aged; Syndrome; Time Factors | 1985 |
[Results of follow-up studies on prognosis after immunotherapy with bestatin in acute nonlymphocytic leukemia].
Topics: Aclarubicin; Acute Disease; Adjuvants, Immunologic; Adolescent; Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Follow-Up Studies; Humans; Leucine; Leukemia; Mercaptopurine; Middle Aged; Naphthacenes; Prednisolone; Prognosis; Random Allocation | 1986 |
Failure of cytarabine in varicella-zoster infections.
Topics: Acute Disease; Adolescent; Adult; Aged; Chickenpox; Clinical Trials as Topic; Cytarabine; DNA, Viral; Female; Herpes Zoster; Herpesvirus 3, Human; Humans; Immunosuppressive Agents; Male; Middle Aged; Neoplasms; Placebos; Time Factors; Virus Replication | 1973 |
Management of adult acute myelogenous leukaemia.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents; BCG Vaccine; Blood Cell Count; Blood Platelets; Child; Cytarabine; Daunorubicin; Humans; Immunotherapy; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Middle Aged; Remission, Spontaneous; Thioguanine | 1973 |
Cytarabine for acute leukemia in adults. Effect of schedule on therapeutic response.
Topics: Acute Disease; Adult; Blood Cell Count; Blood Platelets; Cytarabine; Female; Hemoglobinometry; Humans; Infusions, Parenteral; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Regression, Spontaneous; Remission, Spontaneous; Sex Factors; Time Factors | 1974 |
Chemotherapy of acute leukemia. Comparison of cytarabine alone and in combination with vincristine, prednisone, and cyclophosphamide.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Anemia; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocyte Count; Leukopenia; Male; Middle Aged; Nausea; Prednisone; Time Factors; Vincristine; Vomiting | 1974 |
Therapy of acute leukemia with the combination of cytosine arabinoside (NSC-63878) and cyclophosphamide (NSC-26271).
Topics: Acute Disease; Adolescent; Adult; Aged; Alanine Transaminase; Alopecia; Aspartate Aminotransferases; Bone Marrow Diseases; Child; Clinical Trials as Topic; Cyclophosphamide; Cystitis; Cytarabine; Drug Combinations; Evaluation Studies as Topic; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphoma, Large B-Cell, Diffuse; Male; Middle Aged; Nausea; Remission, Spontaneous; Vomiting | 1970 |
878 other study(ies) available for cytarabine and Acute Disease
| Article | Year |
|---|---|
Variation of levels of plasma guanosine diphosphate L-fucose:beta-D-galactosyl alpha-2-L-fucosyltransferase in acute adult leukemia.
Topics: Acute Disease; Adult; Aged; Female; Fucose; Galactose; Guanosine Diphosphate Fucose; Hexosyltransferases; Humans; Leukemia; Male; Middle Aged | 1977 |
Upper gastrointestinal bleeding secondary to toxicity by anthracyclines, cytarabine and methotrexate in a patient with acute lymphoblastic leukemia.
Topics: Acute Disease; Anthracyclines; Cytarabine; Gastrointestinal Hemorrhage; Humans; Male; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Ulcer | 2022 |
SIRT2 regulates proliferation and chemotherapy response of MLL-ENL-driven acute myeloid leukemia.
Topics: Acute Disease; Amino Acid Sequence; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinogenesis; Cell Proliferation; Cytarabine; Doxorubicin; Gene Expression Regulation, Leukemic; Kaplan-Meier Estimate; Leukemia, Myeloid; Mice, Inbred C57BL; Mice, Knockout; Myeloid-Lymphoid Leukemia Protein; Oncogene Proteins, Fusion; Sequence Homology, Amino Acid; Sirtuin 2; Tumor Cells, Cultured | 2022 |
Outcomes with high dose cytarabine and mitoxantrone induction for adults with mixed phenotype acute leukemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Phenotype; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies | 2023 |
Intensified conditioning regimen with fludarabine combined with post-transplantation cyclophosphamide for haploidentical allogeneic hematopoietic stem cell transplantation in children with high-risk acute leukemia.
Topics: Acute Disease; Adult; Antilymphocyte Serum; Busulfan; Child; Cyclophosphamide; Cytarabine; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Recurrence; Retrospective Studies; Transplantation Conditioning | 2023 |
Prolonged Survival Using Outpatient Palliative Chemotherapy in Two Children With Refractory Acute Myelogenous Leukemia.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Neoplasm, Residual; Outpatients; Quality of Life | 2023 |
Etoposide plus cytarabine versus cyclophosphamide or melphalan in busulfan-based preparative regimens for autologous stem cell transplantation in adults with acute myeloid leukemia in first complete remission: a study from the Acute Leukemia Working Party
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cyclophosphamide; Cytarabine; Etoposide; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Melphalan; Retrospective Studies; Transplantation Conditioning; Transplantation, Autologous | 2023 |
Acute leukemias in 2020: state of the art.
Topics: Acute Disease; Aminopyridines; Antineoplastic Agents; Antineoplastic Agents, Immunological; Congresses as Topic; Cytarabine; Daunorubicin; fms-Like Tyrosine Kinase 3; Gemtuzumab; Glycine; Humans; Leukemia; Pyridines; Recombinant Fusion Proteins; Staurosporine; Triazines | 2020 |
Clinicoepidemiologic Profile and Outcome Predicted by Minimal Residual Disease in Children With Mixed-phenotype Acute Leukemia Treated on a Modified MCP-841 Protocol at a Tertiary Cancer Institute in India.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Chlorambucil; Cytarabine; Female; Follow-Up Studies; Humans; India; Male; Mitoxantrone; Neoplasm, Residual; Phenotype; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Survival Rate | 2020 |
Severe COVID-19 virus reactivation following treatment for B cell acute lymphoblastic leukemia.
Topics: Acute Disease; Antibodies, Viral; Anticoagulants; Betacoronavirus; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; COVID-19 Serotherapy; Cytarabine; Female; Humans; Immunization, Passive; Immunosuppressive Agents; Middle Aged; Pandemics; Pneumonia, Viral; Polymerase Chain Reaction; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Rituximab; SARS-CoV-2; Steroids; Treatment Outcome | 2020 |
Vancomycin-resistant enterococci in acute myeloid leukemia and myelodysplastic syndrome patients undergoing induction chemotherapy with idarubicin and cytarabine.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Cephalosporins; Cytarabine; Female; Gram-Positive Bacterial Infections; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid; Male; Middle Aged; Multivariate Analysis; Myelodysplastic Syndromes; Retrospective Studies; Risk Factors; Vancomycin; Vancomycin-Resistant Enterococci; Young Adult | 2017 |
With me or against me: Tumor suppressor and drug resistance activities of SAMHD1.
Topics: Acute Disease; Animals; Antimetabolites, Antineoplastic; Autoimmune Diseases of the Nervous System; Azacitidine; Cell Line, Tumor; Cell Proliferation; Cytarabine; Decitabine; Drug Resistance; Humans; Leukemia, Myeloid; Monomeric GTP-Binding Proteins; Mutation; Nervous System Malformations; SAM Domain and HD Domain-Containing Protein 1; Survival Analysis; Treatment Outcome; Tumor Suppressor Proteins | 2017 |
D816V mutation in the KIT gene activation loop has greater cell-proliferative and anti-apoptotic ability than N822K mutation in core-binding factor acute myeloid leukemia.
Topics: Acute Disease; Antimetabolites, Antineoplastic; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Core Binding Factors; Cytarabine; Gene Expression Regulation, Leukemic; Humans; Interleukin-13; Janus Kinases; Leukemia, Myeloid; Mitogen-Activated Protein Kinases; Mutation, Missense; Phosphorylation; Proto-Oncogene Proteins c-kit; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; STAT Transcription Factors; Transfection | 2017 |
Remissions after third induction chemotherapy for primary non-responders with acute myeloid leukemia (AML) are uncommon and short-lived.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Induction Chemotherapy; Leukemia, Myeloid; Male; Middle Aged; Remission Induction; Survival Analysis; Young Adult | 2018 |
Analysis of Real-world Data on Postremission Therapy for Acute Myeloid Leukemia With Intermediate Risk Cytogenetics in First Complete Remission.
Topics: Acute Disease; Adult; Antimetabolites, Antineoplastic; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Male; Middle Aged; Outcome Assessment, Health Care; Proportional Hazards Models; Remission Induction; Retrospective Studies; Transplantation Conditioning; Transplantation, Homologous; Whole-Body Irradiation | 2018 |
Outcomes with lower intensity therapy in TP53-mutated acute myeloid leukemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cladribine; Cytarabine; Decitabine; Drug Administration Schedule; Humans; Leukemia, Myeloid; Middle Aged; Mutation; Remission Induction; Survival Analysis; Treatment Outcome; Tumor Suppressor Protein p53 | 2018 |
Systematic patient involvement for homebased outpatient administration of complex chemotherapy in acute leukemia and lymphoma.
Topics: Acute Disease; Adult; Aged; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cytarabine; Female; Humans; Infusion Pumps; Leukemia; Lymphoma; Male; Melphalan; Middle Aged; Outpatients; Podophyllotoxin | 2018 |
A Case of Granulocytic Sarcoma of the Lung in Acute Myeloid Leukemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid; Lung Neoplasms; Male; Middle Aged; Remission Induction; Sarcoma, Myeloid | 2019 |
Acute myeloid leukemia in first remission: to choose transplantation or not?
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Decision Making; Female; Humans; Leukemia, Myeloid; Nucleophosmin; Patient Preference; Remission Induction; Review Literature as Topic; Stem Cell Transplantation; Transplantation, Homologous | 2013 |
The clinical characteristics and prognostic significance of MN1 gene and MN1-associated microRNA expression in adult patients with de novo acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Gene Expression Regulation, Leukemic; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid; Male; MicroRNAs; Middle Aged; Neoplasm Proteins; Nucleophosmin; Peripheral Blood Stem Cell Transplantation; Prognosis; Real-Time Polymerase Chain Reaction; RNA, Neoplasm; Survival Analysis; Trans-Activators; Transplantation, Autologous; Treatment Outcome; Tumor Suppressor Proteins; Vidarabine; Young Adult | 2013 |
Epigenetic action of decitabine (5-aza-2'-deoxycytidine) is more effective against acute myeloid leukemia than cytotoxic action of cytarabine (ARA-C).
Topics: Acute Disease; Aged; Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Cell Survival; Cytarabine; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Drug Approval; HL-60 Cells; Humans; Leukemia, Myeloid; Middle Aged; Remission Induction; Survival Analysis; Treatment Outcome; United States; United States Food and Drug Administration | 2013 |
Efficacy of RNA polymerase II inhibitors in targeting dormant leukaemia cells.
Topics: Acute Disease; Adenine Nucleotides; Antineoplastic Agents; Apoptosis; Arabinonucleosides; Azacitidine; Cell Line, Tumor; Cell Survival; Clofarabine; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Etoposide; Flavonoids; Heterocyclic Compounds, 4 or More Rings; Humans; Leukemia, Myeloid; Piperidines; Purines; RNA Polymerase II; RNA, Neoplasm; Roscovitine; Sirolimus; TOR Serine-Threonine Kinases | 2013 |
Head and neck presentations of B-NHL and B-AL in children/adolescents: experience of the LMB89 study.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Hydrocortisone; Infant; L-Lactate Dehydrogenase; Leucovorin; Leukemia, B-Cell; Lymphoma, B-Cell; Male; Methotrexate; Neoplasm Staging; Prednisone; Vincristine | 2014 |
Laryngeal chloroma heralding relapse of acute myeloid leukemia.
Topics: Acute Disease; Antimetabolites, Antineoplastic; Cytarabine; Disease Progression; Dose Fractionation, Radiation; Fatal Outcome; Humans; Laryngeal Neoplasms; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Recurrence, Local; Palliative Care; Respiratory Insufficiency; Sarcoma, Myeloid; Stem Cell Transplantation; Tomography, X-Ray Computed | 2014 |
Identification of clinically important chromosomal aberrations in acute myeloid leukemia by array-based comparative genomic hybridization.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosome Deletion; Chromosomes, Human, Pair 17; Chromosomes, Human, Pair 5; Comparative Genomic Hybridization; Cytarabine; DNA Copy Number Variations; Drug Administration Schedule; Female; Humans; Idarubicin; Kaplan-Meier Estimate; Karyotype; Leukemia, Myeloid; Male; Middle Aged; Outcome Assessment, Health Care; Prognosis; Remission Induction | 2014 |
Acute myeloid leukemia after myelodysplastic syndrome and failure of therapy with hypomethylating agents: an emerging entity with a poor prognosis.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; DNA Methylation; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Logistic Models; Male; Middle Aged; Multivariate Analysis; Myelodysplastic Syndromes; Outcome Assessment, Health Care; Prognosis; Proportional Hazards Models; Remission Induction; Salvage Therapy; Survival Analysis; Transplantation, Homologous | 2014 |
Factors associated with early reinduction chemotherapy for adults with acute myeloid leukemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Examination; Cell Count; Cytarabine; Humans; Induction Chemotherapy; Leukemia, Myeloid; Middle Aged; Neoplastic Stem Cells; Remission Induction; Retreatment; Time Factors | 2015 |
Response monitoring of infant acute myeloid leukemia treatment by quantification of the tumor specific MLL-FNBP1 fusion gene.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Carrier Proteins; Cytarabine; Fatty Acid-Binding Proteins; Female; Humans; In Situ Hybridization, Fluorescence; Infant; Karyotype; Leukemia, Myeloid; Mitoxantrone; Myeloid-Lymphoid Leukemia Protein; Oncogene Proteins, Fusion; Remission Induction; Treatment Outcome | 2015 |
An autologous leukemia cell vaccine prevents murine acute leukemia relapse after cytarabine treatment.
Topics: Acute Disease; Animals; Antimetabolites, Antineoplastic; Cancer Vaccines; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Combined Modality Therapy; Cytarabine; Dendritic Cells; Galactosylceramides; Green Fluorescent Proteins; Killer Cells, Natural; Leukemia, Myeloid; Mice, Inbred C57BL; Mice, Transgenic; Prognosis; Secondary Prevention; Transplantation, Autologous | 2014 |
[Comparing BFA with BuCyA as a myeloablative conditioning regimen for allogeneic stem cell transplantation in acute leukemias].
Topics: Acute Disease; Busulfan; Cyclophosphamide; Cytarabine; Graft vs Host Disease; Humans; Leukemia, Myeloid, Acute; Remission Induction; Stem Cell Transplantation; Transplantation Conditioning; Transplantation, Homologous; Vidarabine | 2014 |
Sequential development of different acute leukemia types in the same patient.
Topics: Acute Disease; Antineoplastic Agents; Cytarabine; Humans; Idarubicin; Leukemia; Lymph Nodes; Male; Middle Aged; Neoplasm Recurrence, Local | 2014 |
Factors Influencing Pulmonary Toxicity in Children Undergoing Allogeneic Hematopoietic Stem Cell Transplantation in the Setting of Total Body Irradiation-Based Myeloablative Conditioning.
Topics: Acute Disease; Adolescent; Allografts; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Etoposide; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Incidence; Infant; Lung; Male; Pneumonia; Radiotherapy Dosage; Transplantation Conditioning; Whole-Body Irradiation; Young Adult | 2016 |
Chemosensitizing AML cells by targeting bone marrow endothelial cells.
Topics: Acute Disease; Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells; Cell Adhesion; Cell Line, Tumor; Cell Survival; Cells, Cultured; Coculture Techniques; Cytarabine; Endothelial Cells; Flow Cytometry; Humans; Leukemia, Myeloid; Mice, Inbred NOD; Mice, Knockout; Mice, SCID; Microscopy, Confocal; Reactive Oxygen Species; Stilbenes; Time Factors; Xenograft Model Antitumor Assays | 2016 |
Impact of conditioning intensity in T-replete haplo-identical stem cell transplantation for acute leukemia: a report from the acute leukemia working party of the EBMT.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Disease-Free Survival; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Male; Melphalan; Middle Aged; Multivariate Analysis; Mycophenolic Acid; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Transplantation Conditioning; Treatment Outcome | 2016 |
Safety of liposomal cytarabine CNS prophylaxis in children, adolescent and young adult hematopoietic stem cell transplant recipients with acute leukemia and non-Hodgkin lymphoma.
Topics: Acute Disease; Adolescent; Adult; Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Child; Cytarabine; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Liposomes; Lymphoma, Non-Hodgkin; Neoplasm Invasiveness; Treatment Outcome; Young Adult | 2016 |
Ellison RR, Holland JF, Weil M, et al. Arabinosyl cytosine: a useful agent in the treatment of acute leukemia in adults. Blood. 1968;32(4):507-523.
Topics: Acute Disease; Adult; Antimetabolites, Antineoplastic; Cytarabine; History, 20th Century; Humans; Leukemia; Leukemia, Myeloid | 2016 |
Efficacy and Toxicity of Induction Therapy with Cladribine, Idarubicin, and Cytarabine (IAC) for Acute Myeloid Leukemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cytarabine; Diarrhea; Exanthema; Female; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid; Male; Middle Aged; Mucositis; Neutropenia; Remission Induction; Retrospective Studies; Treatment Outcome; Young Adult | 2017 |
Rituximab-induced acute thrombocytopenia: a case report and review of the literature.
Topics: Acute Disease; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Examination; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Humans; Immunophenotyping; Infusions, Parenteral; L-Lactate Dehydrogenase; Lymphoma, Mantle-Cell; Male; Methotrexate; Middle Aged; Platelet Count; Rituximab; Splenomegaly; Thrombocytopenia; Vincristine | 2009 |
Preclinical studies of vorinostat (suberoylanilide hydroxamic acid) combined with cytosine arabinoside and etoposide for treatment of acute leukemias.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Cell Survival; Cytarabine; Drug Evaluation, Preclinical; Drug Synergism; Etoposide; G1 Phase; Humans; Hydroxamic Acids; Leukemia, Myeloid; S Phase; Tumor Cells, Cultured; Vorinostat | 2009 |
Treatment-subgroup interaction: an example from a published, phase II clinical trial.
Topics: Acute Disease; Adult; Amsacrine; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Bias; Clinical Trials, Phase II as Topic; Cytarabine; Humans; Leukemia; Patient Selection; Prednisone; Prognosis; Research Design; Treatment Outcome; Vincristine | 2009 |
Genes of cell-cell interactions, chemotherapy detoxification and apoptosis are induced during chemotherapy of acute myeloid leukemia.
Topics: Acute Disease; Adult; Aged; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Communication; Cluster Analysis; Cytarabine; Female; Flow Cytometry; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Immunoblotting; Inactivation, Metabolic; Leukemia, Myeloid; Leukocytes, Mononuclear; Male; Middle Aged; Oligonucleotide Array Sequence Analysis; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Tumor Suppressor Protein p53 | 2009 |
A comparative study of outcomes of idarubicin- and etoposide-intensified conditioning regimens for allogeneic peripheral blood stem cell transplantation in patients with high-risk acute leukemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Aspergillus; Busulfan; China; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Disease-Free Survival; Etoposide; Female; Graft Survival; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Hydroxyurea; Idarubicin; Immunosuppressive Agents; Leukemia; Leukemia, Myeloid, Acute; Male; Methylprednisolone; Mucositis; Pneumonia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Premedication; Retrospective Studies; Risk Factors; Semustine; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Whole-Body Irradiation | 2009 |
Clofarabine-based salvage chemotherapy for relapsed or refractory acute leukemia before allogeneic stem cell transplantation: results from a case series.
Topics: Acute Disease; Adenine Nucleotides; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cyclophosphamide; Cytarabine; Drug Resistance, Neoplasm; Female; Humans; Leukemia; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Myelomonocytic, Acute; Male; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Salvage Therapy; Stem Cell Transplantation; Transplantation, Homologous; Treatment Outcome | 2009 |
Primary human acute myelogenous leukemia cells release matrix metalloproteases and their inhibitors: release profile and pharmacological modulation.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Angiopoietin-2; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Bortezomib; Cells, Cultured; Chemokines; Coculture Techniques; Culture Media, Serum-Free; Cytarabine; Diterpenes; Endothelial Cells; Female; Humans; Imidazoles; Leukemia, Myeloid; Male; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Middle Aged; Neoplasm Proteins; NF-kappa B; Protease Inhibitors; Pyrazines; Quinoxalines; Receptor, TIE-2; Recombinant Proteins; Tissue Inhibitor of Metalloproteinases; Tumor Cells, Cultured | 2010 |
Last exit clofarabine?
Topics: Acute Disease; Adenine Nucleotides; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Cyclophosphamide; Cytarabine; Humans; Leukemia; Leukemia, Myeloid; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Salvage Therapy; Stem Cell Transplantation; Transplantation, Homologous; Treatment Outcome | 2009 |
Hyperperfusion on magnetic resonance imaging in acute chemotherapy-related leukoencephalopathy.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Cytarabine; Diagnosis, Differential; Humans; Leukoencephalopathies; Magnetic Resonance Imaging; Male; Methotrexate; Polyethylene Glycols; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stroke; Vincristine | 2010 |
A case of acute colitis with severe rectal bleeding in a patient with chronic myeloid leukemia after dasatinib use.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Colitis; Cytarabine; Dasatinib; Female; Gastrointestinal Hemorrhage; Humans; Idarubicin; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Piperazines; Pyrimidines; Rectal Diseases; Thiazoles | 2010 |
Incidence, severity, and etiology of drug-induced acute pancreatitis.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Azathioprine; Child; Child, Preschool; Crohn Disease; Cytarabine; Dexamethasone; Female; Humans; Immunosuppressive Agents; Incidence; Male; Mesalamine; Middle Aged; Mycophenolic Acid; Pancreatitis; Ramipril; Retrospective Studies; Risk Factors; Severity of Illness Index; Valproic Acid; Young Adult | 2010 |
[Successful selection of chemotherapy based on cell surface antigens in a patient with mixed phenotype acute leukemia].
Topics: Acute Disease; Antigens, Surface; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Daunorubicin; Humans; Leukemia; Male; Middle Aged; Prednisolone; Treatment Outcome; Vincristine | 2010 |
Expression of ARC (apoptosis repressor with caspase recruitment domain), an antiapoptotic protein, is strongly prognostic in AML.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Cell Line, Tumor; Cell Survival; Cytarabine; Female; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid; Male; Middle Aged; Multivariate Analysis; Muscle Proteins; Mutation; Oligonucleotides, Antisense; Prognosis; Survival Analysis; Young Adult | 2011 |
Simultaneous acute myeloid leukaemia and de novo acute hepatitis B: a novel management strategy.
Topics: Acute Disease; Antineoplastic Agents; Antiviral Agents; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Guanine; Hepatitis B; Humans; Leukemia, Myeloid; Treatment Outcome; Young Adult | 2011 |
The effect of cerebral spinal fluid replacement on acute myelopathy induced by intrathecal therapy of leukemia.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System; Cerebrospinal Fluid; Cytarabine; Dexamethasone; Female; Fluid Therapy; Humans; Injections, Spinal; Methotrexate; Paraplegia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Spinal Cord Diseases; Treatment Outcome | 2011 |
[Chronic myeloid leukemia complicated with cerebellar hemorrhage and acute hydrocephalus successfully treated with imatinib and intensive supportive care].
Topics: Acute Disease; Antineoplastic Agents; Benzamides; Cerebellum; Cerebral Hemorrhage; Combined Modality Therapy; Critical Care; Cytarabine; Drug Therapy, Combination; Female; Humans; Hydrocephalus; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukostasis; Mannitol; Middle Aged; Piperazines; Pyrimidines; Respiration, Artificial | 2010 |
Flt3-ITD alters chemotherapy response in vitro and in vivo in a p53-dependent manner.
Topics: Acute Disease; Animals; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Blotting, Western; Cytarabine; Disease Models, Animal; DNA Damage; Doxorubicin; Drug Resistance, Neoplasm; fms-Like Tyrosine Kinase 3; Gene Duplication; Humans; Leukemia, Myeloid; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myeloid-Lymphoid Leukemia Protein; Niacinamide; Phenylurea Compounds; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Sorafenib; Survival Analysis; Tandem Repeat Sequences; Tumor Suppressor Protein p53 | 2011 |
Erythroleukemia relapsing as precursor B-cell lymphoblastic leukemia.
Topics: Acute Disease; Antimetabolites, Antineoplastic; Bone Marrow Cells; Cell Lineage; Cell Transformation, Neoplastic; Chromosome Deletion; Chromosomes, Human, Pair 5; Chromosomes, Human, Pair 7; Cytarabine; Drug Therapy, Combination; Humans; Immunophenotyping; Karyotyping; Leukemia, Erythroblastic, Acute; Male; Middle Aged; Monosomy; Naphthacenes; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Recurrence | 2011 |
Liposomal encapsulation of a synergistic molar ratio of cytarabine and daunorubicin enhances selective toxicity for acute myeloid leukemia progenitors as compared to analogous normal hematopoietic cells.
Topics: Acute Disease; Bone Marrow Cells; Cell Proliferation; Cell Survival; Cells, Cultured; Colony-Forming Units Assay; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Combinations; Drug Compounding; Drug Synergism; Flow Cytometry; Humans; Leukemia, Myeloid; Leukocytes, Mononuclear; Liposomes; Stem Cells; Tumor Cells, Cultured | 2011 |
High dose cytarabine and mitoxantrone: an effective induction regimen for high-risk acute myeloid leukemia (AML).
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Combined Modality Therapy; Cytarabine; Diarrhea; Dose-Response Relationship, Drug; Female; fms-Like Tyrosine Kinase 3; Hematologic Diseases; Humans; Infections; Kaplan-Meier Estimate; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Neoplasm Proteins; Neoplasms, Second Primary; Prognosis; Recurrence; Remission Induction; Retrospective Studies; Risk; Stem Cell Transplantation; Transplantation, Homologous; Young Adult | 2012 |
Acute isolated transmural neutropenic gastritis.
Topics: Acute Disease; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Carbazoles; Cytarabine; Daunorubicin; Factor VII Deficiency; Female; Furans; Gastritis; Granulocyte Colony-Stimulating Factor; Humans; Incidental Findings; Leukemia, Myeloid, Acute; Middle Aged; Neutropenia; Recurrence; Tomography, X-Ray Computed; Treatment Outcome | 2012 |
Feasibility of outpatient consolidation chemotherapy in older versus younger patients with acute myeloid leukemia.
Topics: Acute Disease; Adult; Age Factors; Aged; Aged, 80 and over; Ambulatory Care; Anti-Infective Agents; Antineoplastic Combined Chemotherapy Protocols; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Etoposide; Feasibility Studies; Female; Humans; Infections; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Neutropenia; Outpatients; Patient Readmission | 2012 |
Induction chemotherapy versus palliative treatment for acute myeloid leukemia in a consecutive cohort of elderly patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Blood Component Transfusion; Chromosome Aberrations; Cohort Studies; Comorbidity; Cytarabine; Daunorubicin; Etoposide; Female; Follow-Up Studies; Humans; Hydroxyurea; Immunophenotyping; Kaplan-Meier Estimate; Karyotyping; Leukemia, Myeloid; Male; Palliative Care; Remission Induction; Retrospective Studies; Serbia; Treatment Outcome | 2012 |
Influence of obesity on efficacy and toxicity of induction chemotherapy in patients with newly diagnosed acute myeloid leukemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Body Mass Index; Cytarabine; Daunorubicin; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Fever; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid; Male; Middle Aged; Multivariate Analysis; Neutropenia; Obesity; Outcome Assessment, Health Care; Prognosis; Remission Induction; Young Adult | 2013 |
A genome-wide single-nucleotide polymorphism-array can improve the prognostic stratification of the core binding factor acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chromosome Inversion; Core Binding Factors; Cytarabine; Disease-Free Survival; Female; Genome-Wide Association Study; Humans; Idarubicin; Kaplan-Meier Estimate; Karyotyping; Leukemia, Myeloid; Male; Middle Aged; Neoplasm Proteins; Polymorphism, Single Nucleotide; Prognosis; Proportional Hazards Models; Proto-Oncogene Proteins c-kit; Remission Induction; Translocation, Genetic; Young Adult | 2012 |
[Lesions in the nervous system during chemotherapy of acute leukosis and non-Hodgkin lymphomas].
Topics: Acute Disease; Adult; Aged; Antineoplastic Agents; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Prednisolone; Vincristine | 2012 |
Prospective serial evaluation of 2-hydroxyglutarate, during treatment of newly diagnosed acute myeloid leukemia, to assess disease activity and therapeutic response.
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Decitabine; DNA Mutational Analysis; Female; Glutarates; Granulocyte Precursor Cells; Humans; Idarubicin; Isocitrate Dehydrogenase; Leukemia, Myeloid; Male; Middle Aged; Mutation; Prospective Studies; Time Factors | 2012 |
SAB--a promising new treatment to improve remission rates in AML in the elderly?
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Humans; Leukemia, Myeloid; Remission Induction; Thioguanine | 2002 |
The anti-apoptotic genes Bcl-X(L) and Bcl-2 are over-expressed and contribute to chemoresistance of non-proliferating leukaemic CD34+ cells.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antigens, CD34; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; bcl-X Protein; beta 2-Microglobulin; Bone Marrow Cells; Cell Division; Cytarabine; Down-Regulation; fas Receptor; Flow Cytometry; Genes, bcl-2; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid; Middle Aged; Proto-Oncogene Proteins c-bcl-2; Tretinoin | 2002 |
CD7+ and CD56+ myeloid/natural killer cell precursor acute leukemia treated with idarubicin and cytosine arabinoside.
Topics: Acute Disease; Aged; Antigens, CD; Antigens, CD7; Antigens, Differentiation, Myelomonocytic; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; CD56 Antigen; Cytarabine; Daunorubicin; Diagnosis, Differential; Etoposide; Fatal Outcome; Humans; Idarubicin; Killer Cells, Natural; Leukemia, Myeloid; Leukemic Infiltration; Lymphoma, Non-Hodgkin; Male; Mercaptopurine; Mitoxantrone; Myeloid Cells; Neoplastic Stem Cells; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sarcoma, Myeloid; Sialic Acid Binding Ig-like Lectin 3 | 2002 |
Anti-angiogenic activity of the purine analog 6-thioguanine.
Topics: 2-Aminopurine; Acute Disease; Aged; Allantois; Anemia; Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cattle; Cell Line, Transformed; Chick Embryo; Chorion; Cytarabine; Daunorubicin; Drug Evaluation; Endothelial Growth Factors; Endothelium, Vascular; Etoposide; Female; Fibroblast Growth Factor 2; Follow-Up Studies; Humans; Leukemia, Myeloid; Lymphokines; Male; Mice; Mice, Inbred BALB C; Middle Aged; Neovascularization, Pathologic; Neovascularization, Physiologic; Remission Induction; Stress, Mechanical; Thioguanine; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2002 |
[Progress in the field of hematology in the last 100 years: Medical history of acute leukemia].
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; History, 20th Century; Humans; Japan; Leukemia; Mercaptopurine; Prednisolone; Vincristine | 2002 |
Prolonged administration of all-trans retinoic acid in combination with intensive chemotherapy and G-CSF for adult acute myelogenous leukemia: single-centre pilot study in different risk groups.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cytarabine; Disease-Free Survival; Etoposide; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Headache; Humans; Idarubicin; Leukemia, Myeloid; Life Tables; Male; Middle Aged; Neoplastic Stem Cells; Patient Compliance; Pilot Projects; Recombinant Proteins; Remission Induction; Survival Analysis; Treatment Failure; Tretinoin | 2002 |
Stromal cells prevent apoptosis of AML cells by up-regulation of anti-apoptotic proteins.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Animals; Antimetabolites, Antineoplastic; Apoptosis; Bone Marrow Cells; Cell Adhesion; Cell Division; Culture Media, Serum-Free; Cytarabine; DNA Primers; Female; Fluorescent Dyes; HL-60 Cells; Humans; Leukemia, Myeloid; Male; Mice; Middle Aged; Organic Chemicals; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Stromal Cells; Tumor Cells, Cultured; Up-Regulation | 2002 |
Cytarabine-induced acute generalized exanthematous pustulosis.
Topics: Acute Disease; Adolescent; Antimetabolites, Antineoplastic; Cytarabine; Drug Eruptions; Exanthema; Female; Humans; Suppuration | 2002 |
Erythematous eruption in a man with acute myeloid leukemia.
Topics: Acute Disease; Aged; Antimetabolites, Antineoplastic; Cytarabine; Drug Eruptions; Humans; Leukemia, Myeloid; Male | 2002 |
Cellular drug resistance in childhood acute myeloid leukemia is related to chromosomal abnormalities.
Topics: Acute Disease; Adolescent; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Chromosome Aberrations; Chromosome Inversion; Chromosomes, Human; Cladribine; Cytarabine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Infant; Leukemia, Myeloid; Male; Neoplastic Stem Cells; Recurrence; Remission Induction; Tetrazolium Salts; Thiazoles; Translocation, Genetic; Trisomy | 2002 |
Prognostic significance of activating FLT3 mutations in younger adults (16 to 60 years) with acute myeloid leukemia and normal cytogenetics: a study of the AML Study Group Ulm.
Topics: Acute Disease; Adolescent; Adult; Alleles; Amino Acid Substitution; Antimetabolites, Antineoplastic; Codon; Cytarabine; Female; fms-Like Tyrosine Kinase 3; Follow-Up Studies; Gene Deletion; Gene Duplication; Humans; In Situ Hybridization, Fluorescence; Leukemia, Myeloid; Leukocyte Count; Male; Middle Aged; Mutation; Prognosis; Proportional Hazards Models; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Survival Analysis; Treatment Outcome | 2002 |
Deoxycytidine kinase expression and activity in patients with resistant versus sensitive acute myeloid leukemia.
Topics: Acute Disease; Antimetabolites, Antineoplastic; Cytarabine; Deoxycytidine Kinase; Drug Resistance, Neoplasm; Enzyme Activation; Humans; Leukemia, Myeloid; Recurrence | 2002 |
Blast crisis of chronic myeloid leukemia: diagnosis prompted by T(8;9).
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Bone Marrow Transplantation; Child, Preschool; Chromosomes, Human, Pair 8; Chromosomes, Human, Pair 9; Combined Modality Therapy; Cytarabine; Daunorubicin; Ethmoid Sinus; Etoposide; Fusion Proteins, bcr-abl; Humans; Karyotyping; Leukemia, Myeloid, Accelerated Phase; Male; Meninges; Mitoxantrone; Remission Induction; Sacrococcygeal Region; Sarcoma, Myeloid; Thioguanine; Translocation, Genetic | 2002 |
Immunophenotypic evidence of leukemia after induction therapy predicts relapse: results from a prospective Children's Cancer Group study of 252 patients with acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Antigens, CD; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Examination; California; Child; Child, Preschool; Cytarabine; Daunorubicin; Dexamethasone; Etoposide; Female; Flow Cytometry; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Immunophenotyping; Infant; Leukemia, Myeloid; Male; Multicenter Studies as Topic; Myelodysplastic Syndromes; Neoplasm, Residual; Prognosis; Prospective Studies; Randomized Controlled Trials as Topic; Recurrence; Remission Induction; Risk Factors; Single-Blind Method; Survival Analysis; Thioguanine; Treatment Outcome | 2003 |
Cholesterol-modulating agents kill acute myeloid leukemia cells and sensitize them to therapeutics by blocking adaptive cholesterol responses.
Topics: Acute Disease; Antineoplastic Agents; Bone Marrow Cells; Bridged Bicyclo Compounds, Heterocyclic; Cholesterol; Cytarabine; Daunorubicin; Drug Synergism; HL-60 Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leukemia, Myeloid; Lipoproteins, LDL; Lovastatin; Membrane Lipids; Protein Prenylation; Protein Processing, Post-Translational; Radiation-Sensitizing Agents; Tricarboxylic Acids; Tumor Cells, Cultured | 2003 |
Diphtheria toxin-interleukin-3 fusion protein (DT(388)IL3) prolongs disease-free survival of leukemic immunocompromised mice.
Topics: Acute Disease; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Cytarabine; Diphtheria Toxin; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunocompromised Host; Injections, Intraperitoneal; Injections, Intravenous; Injections, Subcutaneous; Interleukin-2; Interleukin-3; Leukemia, Myeloid; Mice; Mice, Inbred BALB C; Mice, SCID; Neoplastic Stem Cells; Recombinant Fusion Proteins | 2003 |
Salvage therapy in refractory acute myeloid leukemia: prediction of outcome based on analysis of prognostic factors.
Topics: Acute Disease; Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Cytarabine; Drug Evaluation; Female; Humans; Karyotyping; Leukemia, Myeloid; Male; Middle Aged; Prognosis; Prospective Studies; Remission Induction; Retrospective Studies; Risk Factors; Salvage Therapy; Survival Analysis; Treatment Outcome | 2003 |
Posterior leukoencephalopathy following intrathecal chemotherapy with MRA-documented vasospasm.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Blindness; Brain Diseases; Cerebral Arteries; Cerebral Infarction; Cytarabine; Disease Progression; Female; Humans; Injections, Spinal; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Methotrexate; Middle Aged; Ocular Motility Disorders; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recovery of Function; Syndrome; Tachycardia; Vasospasm, Intracranial | 2003 |
New designs for phase 2 clinical trials.
Topics: Acute Disease; Adenine Nucleotides; Adult; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Bayes Theorem; Bias; Biomarkers; Clinical Trials, Phase II as Topic; Clofarabine; Confounding Factors, Epidemiologic; Cytarabine; Daunorubicin; Drug Carriers; False Negative Reactions; Follow-Up Studies; Humans; Idarubicin; Leukemia, Myeloid; Liposomes; Middle Aged; Patient Selection; Randomized Controlled Trials as Topic; Remission Induction; Research Design; Thalidomide; Topotecan; Treatment Outcome | 2003 |
Maternal and fetal outcomes in pregnancy complicated with acute leukemia: a single institutional experience with 10 pregnancies at 16 years.
Topics: Abortion, Spontaneous; Abortion, Therapeutic; Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Fatal Outcome; Female; Fetal Death; Follow-Up Studies; Gestational Age; Humans; Infant, Newborn; Leukemia, Myeloid; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pregnancy; Pregnancy Complications, Neoplastic; Pregnancy Outcome; Retrospective Studies; Turkey | 2003 |
HLA-DR antigen-negative acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cytarabine; Disease-Free Survival; Female; Flow Cytometry; HLA-DR Antigens; Humans; Idarubicin; Immunophenotyping; Karyotyping; Leukemia, Myeloid; Male; Middle Aged; Neoplastic Stem Cells; Prospective Studies; Recurrence; Treatment Outcome | 2003 |
In AML cell lines Ara-C combined with purine analogues is able to exert synergistic as well as antagonistic effects on proliferation, apoptosis and disruption of mitochondrial membrane potential.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Division; Cytarabine; Drug Antagonism; Drug Synergism; Humans; Intracellular Membranes; Leukemia, Myeloid; Membrane Potentials; Mitochondria; Purines; Tumor Cells, Cultured | 2003 |
Survival of acute myeloid leukemia cells requires PI3 kinase activation.
Topics: Acute Disease; Animals; Cell Survival; Cytarabine; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Everolimus; Humans; Leukemia, Myeloid; Mice; Mice, SCID; Neoplasms, Experimental; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Signal Transduction; Sirolimus; Transplantation, Heterologous | 2003 |
Mucormycosis in acute myeloid leukaemia.
Topics: Acute Disease; Amphotericin B; Antifungal Agents; Combined Modality Therapy; Cytarabine; Frozen Sections; Humans; Idarubicin; Immunosuppressive Agents; Leukemia, Myeloid; Male; Middle Aged; Mucormycosis; Thoracic Wall | 2003 |
Immunophenotyping is an independent factor for risk stratification in AML.
Topics: Acute Disease; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Cytarabine; Daunorubicin; Female; Humans; Immunophenotyping; Leukemia, Myeloid; Male; Middle Aged; Multivariate Analysis; Predictive Value of Tests; Prognosis; Retrospective Studies; Risk Factors; Survival Analysis | 2003 |
Autologous peripheral blood stem cell transplantation in first remission adult acute myeloid leukaemia--an intention to treat analysis and comparison of outcome using a predictive model based on the MRC AML10 cohort.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Clinical Trials as Topic; Cohort Studies; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Humans; Leukemia, Myeloid; Life Tables; Male; Middle Aged; Models, Biological; Peripheral Blood Stem Cell Transplantation; Remission Induction; Risk; Survival Analysis; Thioguanine; Transplantation Conditioning; Transplantation, Autologous; Treatment Outcome | 2003 |
The presence of an HLA-identical sibling donor has no impact on outcome of patients with high-risk MDS or secondary AML (sAML) treated with intensive chemotherapy followed by transplantation: results of a prospective study of the EORTC, EBMT, SAKK and GIM
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Disease-Free Survival; Etoposide; Female; Follow-Up Studies; Histocompatibility Testing; Humans; Idarubicin; Leukemia, Myeloid; Living Donors; Male; Middle Aged; Myelodysplastic Syndromes; Prospective Studies; Remission Induction; Risk Factors; Stem Cell Transplantation; Transplantation Conditioning; Transplantation, Autologous; Treatment Outcome | 2003 |
Comparison of fludarabine-containing salvage chemotherapy regimens for relapsed/refractory acute myelogenous leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Humans; Leukemia, Myeloid; Middle Aged; Neoplasm Recurrence, Local; Remission Induction; Salvage Therapy; Treatment Outcome; Vidarabine | 2003 |
Timed-sequential chemotherapy with concomitant granulocyte colony-stimulating factor for newly diagnosed de novo acute myelogenous leukemia.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Palliative Care; Remission Induction; Risk Factors; Survival Rate; Time Factors; Treatment Outcome | 2003 |
Cytotoxic drugs enhance the ex vivo sensitivity of malignant cells from a subset of acute myeloid leukaemia patients to apoptosis induction by tumour necrosis factor receptor-related apoptosis-inducing ligand.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Caspase 3; Caspases; Cytarabine; Daunorubicin; Drug Interactions; Humans; Leukemia, Myeloid; Membrane Glycoproteins; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Vidarabine | 2003 |
A hybrid form of myeloid/NK-cell acute leukemia and myeloid/NK-cell precursor acute leukemia.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carmustine; CD2 Antigens; Cytarabine; Flow Cytometry; Humans; Immunophenotyping; Killer Cells, Natural; Leukemia, Lymphoid; Male; Melphalan; Podophyllotoxin | 2003 |
Successful treatment with intermediate dose cytosine arabinoside for myelodysplastic syndrome with acute myelofibrosis.
Topics: Acute Disease; Cytarabine; Humans; Male; Middle Aged; Myelodysplastic Syndromes; Primary Myelofibrosis; Remission Induction; Treatment Outcome | 2003 |
Deoxycytidine kinase and cN-II nucleotidase expression in blast cells predict survival in acute myeloid leukaemia patients treated with cytarabine.
Topics: 5'-Nucleotidase; Acute Disease; Aged; Antimetabolites, Antineoplastic; Biomarkers, Tumor; Cytarabine; Deoxycytidine Kinase; Disease-Free Survival; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Polymerase Chain Reaction; Prognosis; Retrospective Studies; RNA, Messenger; RNA, Neoplasm; Survival Analysis; Treatment Outcome | 2003 |
Cytarabine-induced corneal toxicity.
Topics: Acute Disease; Adult; Antimetabolites, Antineoplastic; Corneal Diseases; Cytarabine; Humans; Leukemia, Myeloid; Male; Vision Disorders | 2003 |
[The therapeutic effects of FLAG regime for refractory and relapsing acute leukemia].
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia; Male; Middle Aged; Recurrence; Vidarabine | 2003 |
Risk of acute leukemia following epirubicin-based adjuvant chemotherapy: a report from the National Cancer Institute of Canada Clinical Trials Group.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Cyclophosphamide; Cytarabine; Epirubicin; Female; Fluorouracil; Humans; Leukemia; Methotrexate; Middle Aged; Neoplasms, Multiple Primary; Risk | 2003 |
[Allergic reaction against an emulsifier, HCO-60, contained in multamin and enocitabine].
Topics: Acute Disease; Antineoplastic Agents; Castor Oil; Cytarabine; Drug Hypersensitivity; Female; Humans; Leukemia; Middle Aged; Surface-Active Agents; Urticaria; Vitamins | 2003 |
Myeloid/natural killer cell precursor acute leukemia accompanied by homozygous protein C deficiency.
Topics: Acute Disease; Adult; Antibiotics, Antineoplastic; Anticoagulants; Antimetabolites, Antineoplastic; Cytarabine; Heparin, Low-Molecular-Weight; Homozygote; Humans; Idarubicin; Killer Cells, Natural; Leukemia, Myeloid; Male; Myeloid Cells; Neoplastic Stem Cells; Pedigree; Protein C Deficiency | 2003 |
Cytarabine syndrome revisited.
Topics: Acute Disease; Adult; Antimetabolites, Antineoplastic; Cytarabine; Female; Fever; Humans; Leukemia, Myeloid; Syndrome | 2003 |
Acute pericarditis and pleural effusion complicating cytarabine chemotherapy.
Topics: Acute Disease; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Leukemia, Myelomonocytic, Acute; Male; Middle Aged; Pericarditis; Pleural Effusion; Recurrence | 2003 |
Mylotarg, fludarabine, cytarabine (ara-C), and cyclosporine (MFAC) regimen as post-remission therapy in acute myelogenous leukemia.
Topics: Acute Disease; Adult; Aged; Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cyclosporine; Cytarabine; Female; Gemtuzumab; Humans; Leukemia, Myeloid; Male; Middle Aged; Recurrence; Remission Induction; Vidarabine | 2003 |
Intestinal toxicity during induction chemotherapy with cytarabine-based regimens in adult acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Evaluation; Drug-Related Side Effects and Adverse Reactions; Enterocolitis, Necrotizing; Female; Humans; Infusions, Parenteral; Injections, Subcutaneous; Intestinal Diseases; Leukemia, Myeloid; Male; Middle Aged; Neutropenia; Remission Induction; Retrospective Studies; Thrombocytopenia | 2003 |
Chemotherapy increases transgene expression in leukemic cells.
Topics: Acute Disease; Animals; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Gene Expression; Genetic Therapy; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Lac Operon; Leukemia, Myeloid; Mice; Neoplasm Transplantation; Transfection; Transgenes; Tumor Cells, Cultured | 2003 |
Infectious complications in pediatric acute myeloid leukemia: analysis of the prospective multi-institutional clinical trial AML-BFM 93.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bacteremia; Bacteria; Child; Child, Preschool; Clinical Trials as Topic; Cytarabine; Down Syndrome; Etoposide; Female; Fever; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans; Infant; Infant, Newborn; Leukemia, Myeloid; Male; Mitoxantrone; Neutropenia; Prospective Studies; Retrospective Studies; Thioguanine | 2004 |
Mutations in the tyrosine kinase domain of FLT3 define a new molecular mechanism of acquired drug resistance to PTK inhibitors in FLT3-ITD-transformed hematopoietic cells.
Topics: Acute Disease; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Cell Division; Cell Line, Transformed; Cytarabine; DNA-Binding Proteins; Drug Resistance, Neoplasm; Enzyme Inhibitors; fms-Like Tyrosine Kinase 3; Genistein; Humans; Indoles; Leukemia, Myeloid; MAP Kinase Signaling System; Milk Proteins; Mutagenesis; Phenotype; Phosphorylation; Protein Structure, Tertiary; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; STAT5 Transcription Factor; Staurosporine; Trans-Activators; Tyrphostins | 2004 |
Children with acute myeloblastic leukemia presenting with extramedullary infiltration: the effects of high-dose steroid treatment.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Bone Marrow Cells; CD13 Antigens; Child; Child, Preschool; Cytarabine; Female; Humans; Leukemia, Myeloid; Leukemic Infiltration; Lipopolysaccharide Receptors; Male; Methylprednisolone; Mitoxantrone; Prognosis; Remission Induction; Survival Rate; Thioguanine; Treatment Outcome | 2004 |
Prognostic relevance of immunophenotyping in 379 patients with acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cytarabine; Cytogenetics; Daunorubicin; DNA Nucleotidylexotransferase; Female; Humans; Immunophenotyping; Leukemia, Myeloid; Male; Middle Aged; Prognosis; Remission Induction; Survival Rate | 2004 |
Low L-selectin (CD62L) expression in acute myeloid leukemia correlates with a bad cytogenetic risk.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells; Chromosome Aberrations; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; L-Selectin; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Neoplasm Proteins; Neoplastic Stem Cells; Remission Induction; Risk; Thioguanine; Treatment Outcome; Tretinoin | 2003 |
Expression of inducible Bcl-X(S) in myeloid leukemia: compensatory upregulation of Bcl-X(L) and Bcl-2 prevents apoptosis and chemosensitization.
Topics: Acute Disease; Antimetabolites, Antineoplastic; Apoptosis; bcl-X Protein; Cell Cycle; Cytarabine; HL-60 Cells; Humans; Leukemia, Myeloid; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured; Up-Regulation | 2004 |
Isolated hyperbilirubinemia following standard dose cytosine arabinoside in a patient with relapsed acute myeloid leukemia.
Topics: Acute Disease; Antimetabolites, Antineoplastic; Cytarabine; Female; Humans; Hyperbilirubinemia; Leukemia, Myeloid; Middle Aged; Recurrence | 2004 |
Tailored therapy of adult acute leukaemia in Jehovah's Witnesses: unjustified reluctance to treat.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Case Management; Cytarabine; Daunorubicin; Etoposide; Female; Hemoglobins; Hemorrhage; Humans; Jehovah's Witnesses; Leukemia; Male; Middle Aged; Multiple Organ Failure; Patient Acceptance of Health Care; Refusal to Treat; Remission Induction; Tretinoin; Vincristine | 2004 |
Valproic acid inhibits proliferation and induces apoptosis in acute myeloid leukemia cells expressing P-gp and MRP1.
Topics: Acute Disease; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; CASP8 and FADD-Like Apoptosis Regulating Protein; Cell Division; Cell Line, Tumor; Cytarabine; Drug Evaluation, Preclinical; Drug Resistance, Multiple; Drug Synergism; Enzyme Inhibitors; Humans; Intracellular Signaling Peptides and Proteins; Leukemia, Myeloid; Multidrug Resistance-Associated Proteins; Tumor Cells, Cultured; Valproic Acid | 2004 |
P-glycoprotein (Pgp) modulation in untreated acute myeloid leukemia (AML): Cancer and Leukemia Group B (CALGB) trials in younger and older adults.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Clinical Trials, Phase I as Topic; Clinical Trials, Phase III as Topic; Cytarabine; Daunorubicin; Etoposide; Humans; Leukemia, Myeloid; Middle Aged; Treatment Outcome | 2004 |
5'-(3')-nucleotidase mRNA levels in blast cells are a prognostic factor in acute myeloid leukemia patients treated with cytarabine.
Topics: Acute Disease; Antimetabolites, Antineoplastic; Blast Crisis; Cytarabine; Humans; Leukemia, Myeloid; Molecular Sequence Data; Nucleotidases; Prognosis; RNA, Messenger | 2004 |
Differentiating agents + low-dose chemotherapy in the management of old/poor prognosis patients with acute myeloid leukemia or myelodysplastic syndrome.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Calcitriol; Cytarabine; Disease Progression; Female; Humans; Isotretinoin; Leukemia, Myeloid; Male; Middle Aged; Myelodysplastic Syndromes; Thioguanine | 2004 |
A G-quadruplex-interactive agent, telomestatin (SOT-095), induces telomere shortening with apoptosis and enhances chemosensitivity in acute myeloid leukemia.
Topics: Acute Disease; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Apoptosis; Cytarabine; Daunorubicin; DNA-Binding Proteins; Drug Resistance, Neoplasm; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Oxazoles; Telomerase; Telomere; U937 Cells | 2004 |
Cytosine arabinoside induces costimulatory molecule expression in acute myeloid leukemia cells.
Topics: Acute Disease; Animals; Antigens, CD; B7-1 Antigen; B7-2 Antigen; B7-H1 Antigen; Blood Proteins; Cell Line, Tumor; Cytarabine; Cytotoxicity, Immunologic; Humans; Leukemia, Myeloid; Membrane Glycoproteins; Mice; Mice, Inbred C3H; Peptides; T-Lymphocytes, Cytotoxic; Up-Regulation | 2004 |
In vitro evaluation of cytochrome P450-mediated drug interactions between cytarabine, idarubicin, itraconazole and caspofungin.
Topics: Acute Disease; Antifungal Agents; Aryl Hydrocarbon Hydroxylases; Caspofungin; Cytarabine; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Drug Interactions; Echinocandins; Humans; Idarubicin; Itraconazole; Leukemia, Myeloid; Lipopeptides; Mycoses; Peptides; Peptides, Cyclic; Substrate Specificity | 2004 |
Functional analysis of apoptosis induction in acute myeloid leukaemia-relevance of karyotype and clinical treatment response.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Apoptosis; Caspase 3; Caspases; Cytarabine; Enzyme Activation; Etoposide; Fas Ligand Protein; Female; Humans; Karyotyping; Leukemia, Myeloid; Male; Membrane Glycoproteins; Middle Aged; Nucleic Acid Synthesis Inhibitors; Treatment Outcome | 2004 |
No preferential sensitivity of t(8;21) acute myeloid leukemias to cytosine arabinoside in vitro: is intensity of therapy or high dose Ara-C crucial for response?
Topics: Acute Disease; Adult; Aged; Apoptosis; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Cytarabine; DNA, Neoplasm; Drug Resistance, Neoplasm; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Translocation, Genetic; Tumor Cells, Cultured | 2004 |
[Damage of vascular endothelium in the treatment of acute leukemia: in vitro study].
Topics: Acute Disease; Antineoplastic Agents; Cell Survival; Cells, Cultured; Culture Media; Cytarabine; Daunorubicin; Endothelial Cells; Endothelium, Vascular; Flow Cytometry; Humans; Immunohistochemistry; Leukemia; Models, Biological; Time Factors; Umbilical Veins | 2004 |
A real-time quantitative RT-PCR assay for monitoring DEK-CAN fusion transcripts arising from translocation t(6;9) in acute myeloid leukemia.
Topics: Acute Disease; Animals; Chromosomes, Human, Pair 6; Chromosomes, Human, Pair 9; Cytarabine; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-3; Leukemia, Myeloid; Mice; Mice, SCID; Oncogene Proteins; Oncogene Proteins, Fusion; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; Translocation, Genetic | 2004 |
Pressure-induced bullae and sweat gland necrosis following chemotherapy induction.
Topics: Acute Disease; Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Blister; Cytarabine; Drug Eruptions; Drug-Related Side Effects and Adverse Reactions; Humans; Idarubicin; Leukemia, Myeloid; Male; Necrosis; Remission Induction; Sweat Gland Diseases; Sweat Glands | 2004 |
The effect of G-CSF on the in vitro cytotoxicity of cytarabine and fludarabine in the FLAG combination in pediatric acute myeloid leukemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cell Proliferation; Cell Survival; Child; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Male; Tumor Cells, Cultured; Vidarabine | 2004 |
Breast cancer resistance protein and P-glycoprotein in 149 adult acute myeloid leukemias.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Proliferation; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Gene Expression Regulation, Leukemic; Humans; Idarubicin; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Neoplasm Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Survival Rate | 2004 |
Cytarabine-induced fever complicating the clinical course of leukemia.
Topics: Acute Disease; Adult; Aged; Antimetabolites, Antineoplastic; Cytarabine; Female; Fever; Humans; Leukemia, Myeloid; Male; Middle Aged; Remission Induction; Retrospective Studies | 2005 |
PI3-kinase/Akt is constitutively active in primary acute myeloid leukaemia cells and regulates survival and chemoresistance via NF-kappaB, Mapkinase and p53 pathways.
Topics: Acute Disease; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, CD34; Antimetabolites, Antineoplastic; Cell Survival; Chromones; Cytarabine; Drug Resistance, Neoplasm; Enzyme Inhibitors; Humans; Leukemia, Myeloid; MAP Kinase Signaling System; Membrane Glycoproteins; Morpholines; NF-kappa B; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2005 |
Acute pancreatitis during all-trans-retinoic acid treatment for acute promyelocytic leukemia in a patient without overt hypertriglyceridemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Hypertriglyceridemia; Idarubicin; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Pancreatitis; Tretinoin | 2005 |
Cellular drug sensitivity in MLL-rearranged childhood acute leukaemia is correlated to partner genes and cell lineage.
Topics: Acute Disease; Adolescent; Antineoplastic Agents; Cell Lineage; Child; Child, Preschool; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 9; Cytarabine; Cytotoxicity Tests, Immunologic; DNA-Binding Proteins; Doxorubicin; Drug Resistance, Neoplasm; Female; Fluorometry; Gene Rearrangement; Glucocorticoids; Histone-Lysine N-Methyltransferase; Humans; Infant; Infant, Newborn; Leukemia, Myeloid; Male; Myeloid-Lymphoid Leukemia Protein; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Proto-Oncogenes; Statistics, Nonparametric; Transcription Factors; Translocation, Genetic | 2005 |
Disease biology rather than age is the most important determinant of survival of patients > or = 60 years with acute myeloid leukemia treated with uniform intensive therapy.
Topics: Acute Disease; Age Factors; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Follow-Up Studies; Hematologic Diseases; Humans; Karyotyping; L-Lactate Dehydrogenase; Leukemia, Myeloid; Leukocyte Count; Male; Middle Aged; Myelodysplastic Syndromes; Remission Induction; Retrospective Studies; Survival Rate; Treatment Outcome | 2005 |
[Sensitivity of survivin-positive primary leukemia cells to chemotherapy].
Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Antineoplastic Agents; Cell Survival; Cytarabine; Drug Screening Assays, Antitumor; Female; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Apoptosis Proteins; Leukemia; Male; Microtubule-Associated Proteins; Middle Aged; Neoplasm Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Survivin; Tumor Cells, Cultured | 2005 |
Deguelin, A PI3K/AKT inhibitor, enhances chemosensitivity of leukaemia cells with an active PI3K/AKT pathway.
Topics: Acute Disease; Antigens, CD34; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cells, Cultured; Cytarabine; Drug Resistance, Neoplasm; Erythropoietin; Etoposide; HL-60 Cells; Humans; Leukemia; Leukemia, Myeloid; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Rotenone; Signal Transduction; Stem Cell Factor; Stem Cells | 2005 |
TRAIL decoy receptors mediate resistance of acute myeloid leukemia cells to TRAIL.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 8; Cell Differentiation; Cell Membrane; Cytarabine; Drug Resistance, Neoplasm; Etoposide; Female; GPI-Linked Proteins; Granulocytes; HL-60 Cells; Humans; Hydroxyurea; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Monocytes; Oncogene Proteins, Fusion; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Member 10c; Recombinant Fusion Proteins; Tretinoin; Tumor Cells, Cultured; Tumor Necrosis Factor Decoy Receptors; Tumor Stem Cell Assay; U937 Cells | 2005 |
Limited value of FLT3 mRNA expression in the bone marrow for prognosis and monitoring of patients with acute myeloid leukemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Marrow; Combined Modality Therapy; Cytarabine; Daunorubicin; Etoposide; Female; fms-Like Tyrosine Kinase 3; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Male; Middle Aged; Neoplasm Proteins; Neoplasm, Residual; Prognosis; Remission Induction; RNA, Messenger; RNA, Neoplasm; Survival Analysis; Tretinoin | 2005 |
Pretreatment prognostic factors and treatment outcome in elderly patients with de novo acute myeloid leukemia.
Topics: Acute Disease; Aged; Aged, 80 and over; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Chromosome Aberrations; Cytarabine; Female; Hemoglobins; Humans; Karyotyping; L-Lactate Dehydrogenase; Leukemia, Myeloid; Leukocyte Count; Male; Neoplasm Staging; Platelet Count; Prognosis; Remission Induction; Risk Factors; Survival Rate; Treatment Outcome | 2005 |
Autologous or allogeneic stem cell transplantation as post-remission therapy in refractory or relapsed acute myeloid leukemia after highly intensive chemotherapy.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Etoposide; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Neoplasm Recurrence, Local; Remission Induction; Salvage Therapy; Stem Cell Transplantation; Survival Rate; Transplantation, Autologous; Transplantation, Homologous; Treatment Outcome | 2005 |
Administration of mylotarg 4 days after beginning of a chemotherapy including intermediate-dose aracytin and mitoxantrone (MIDAM regimen) produces a high rate of complete hematologic remission in patients with CD33+ primary resistant or relapsed acute mye
Topics: Acute Disease; Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Gemtuzumab; Humans; Leukemia, Myeloid; Mitoxantrone; Recurrence; Remission Induction; Salvage Therapy; Sialic Acid Binding Ig-like Lectin 3 | 2005 |
FLAG-IDA in the treatment of refractory/relapsed acute leukaemias: single centre study.
Topics: Acute Disease; Adolescent; Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Vidarabine | 2005 |
Prognostic factors and outcome of core binding factor acute myeloid leukemia patients with t(8;21) differ from those of patients with inv(16): a Cancer and Leukemia Group B study.
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Aziridines; Benzoquinones; Chromosome Aberrations; Cyclophosphamide; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Prognosis; Proportional Hazards Models; Prospective Studies; Remission Induction; Statistics, Nonparametric; Survival Analysis | 2005 |
Chemotherapy for acute myeloid leukemias with cytosine arabinoside, daunorubicin, etoposide, and mitoxantrone may cause permanent oligoasthenozoospermia or amenorrhea in middle-aged patients.
Topics: Acute Disease; Adult; Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Oligospermia; Sperm Motility; Spermatozoa | 2005 |
Acute myeloid leukemia treatment in patients over 60 years of age. Comparison of symptomatic, palliative, and aggressive therapy.
Topics: Acute Disease; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Hematopoietic Stem Cell Transplantation; Hospitalization; Humans; Hydroxyurea; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Palliative Care; Prognosis; Remission Induction; Retrospective Studies; Survival Analysis; Treatment Outcome | 2005 |
The use of biochemical markers in cardiotoxicity monitoring in patients treated for leukemia.
Topics: Acute Disease; Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Creatine Kinase, MB Form; Cytarabine; Echocardiography; Female; Heart Diseases; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Natriuretic Peptide, Brain; Peptide Fragments; Troponin T | 2005 |
"3+7" therapy for the treatment of acute myeloid leukemia. PRO.
Topics: Acute Disease; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Therapy, Combination; Humans; Leukemia, Myeloid; Remission Induction; Treatment Outcome | 2005 |
T-cell acute lymphoblastic leukemia relapsing as acute myelogenous leukemia.
Topics: Acute Disease; Adolescent; Antigens, CD7; Antigens, Differentiation, T-Lymphocyte; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow; Cell Differentiation; Cell Lineage; Core Binding Factor Alpha 2 Subunit; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Diagnosis, Differential; Doxorubicin; Etoposide; Fatal Outcome; Female; Gene Dosage; Histone-Lysine N-Methyltransferase; Humans; Immunophenotyping; Karyotyping; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Myeloid-Lymphoid Leukemia Protein; Neoplasms, Second Primary; Neoplastic Stem Cells; Proto-Oncogenes; Recurrence; T-Lymphocyte Subsets; Vincristine | 2007 |
WT1 gene expression in children with Down syndrome and transient myeloproliferative disorder.
Topics: Acute Disease; Cytarabine; Down Syndrome; Female; Follow-Up Studies; GATA1 Transcription Factor; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Genes, Wilms Tumor; Humans; Infant, Newborn; Leukemia, Myeloid; Longitudinal Studies; Male; Mutation; Myeloproliferative Disorders; Reverse Transcriptase Polymerase Chain Reaction; Treatment Outcome | 2006 |
Modeling the pharmacodynamics of highly schedule-dependent agents: exemplified by cytarabine-based regimens in acute myeloid leukemia.
Topics: Acute Disease; Adult; Algorithms; Antimetabolites, Antineoplastic; Area Under Curve; Bone Marrow Cells; Cell Survival; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid; Meta-Analysis as Topic; Models, Biological; Randomized Controlled Trials as Topic | 2005 |
Genetics in the management of adult de novo AML.
Topics: Acute Disease; Adult; Aged; Antimetabolites, Antineoplastic; Chromosome Aberrations; Chromosome Banding; Cytarabine; Hematopoietic Stem Cell Transplantation; Humans; In Situ Hybridization, Fluorescence; Karyotyping; Leukemia, Myeloid; Middle Aged; Multicenter Studies as Topic; Prognosis; Prospective Studies; Translocation, Genetic; Transplantation, Autologous; Treatment Outcome | 2003 |
Clinical significance of development of Philadelphia-chromosome negative clones in patients with chronic myeloid leukemia treated with imatinib mesylate.
Topics: Acute Disease; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Bone Marrow; Clone Cells; Cytarabine; Disease Progression; Fatal Outcome; Fusion Proteins, bcr-abl; Granulocyte Colony-Stimulating Factor; Humans; Hydroxyurea; Imatinib Mesylate; In Situ Hybridization, Fluorescence; Interferons; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Leukemia, Myeloid, Chronic-Phase; Male; Middle Aged; Neoplastic Stem Cells; Philadelphia Chromosome; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Selection, Genetic; Vidarabine | 2005 |
CD79a expression in acute myeloid leukemia t(8;21) and the importance of cytogenetics in the diagnosis of leukemias with immunophenotypic ambiguity.
Topics: Acute Disease; Adult; Antigens, CD; B-Lymphocytes; Blast Crisis; Bone Marrow Cells; CD79 Antigens; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Cytarabine; Flow Cytometry; Humans; Immunophenotyping; In Situ Hybridization, Fluorescence; Leukemia, Myeloid; Male; T-Lymphocytes; Translocation, Genetic | 2005 |
Non-anthracycline based remission induction therapy for newly diagnosed patients with acute myeloid leukemia aged 60 or older.
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Middle Aged; Remission Induction; Vidarabine | 2006 |
Nfl gene inactivation in acute myeloid leukemia cells confers cytarabine resistance through MAPK and mTOR pathways.
Topics: Acute Disease; Animals; Cell Death; Cell Line, Tumor; Cytarabine; Drug Resistance, Neoplasm; Humans; Leukemia, Myeloid; Mice; Mitogen-Activated Protein Kinases; Neurofibromin 1; Protein Kinases; Signal Transduction; TOR Serine-Threonine Kinases | 2006 |
[What was the cause of fever, neck pain and arm paresis? Normal blood picture led to error].
Topics: Acute Disease; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arm; Cytarabine; Fever; Humans; Leukemia, Myeloid; Male; Mitoxantrone; Neck Pain; Paresis; Prognosis; Recurrence; Remission Induction | 2005 |
The prognostic value of cN-II and cN-III enzymes in adult acute myeloid leukemia.
Topics: 5'-Nucleotidase; Acute Disease; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells; Cytarabine; Drug Resistance, Neoplasm; Female; Glycoproteins; Humans; Leukemia, Myeloid; Male; Middle Aged; Neoplasm Proteins; Neoplastic Stem Cells; Prognosis; Proportional Hazards Models; Pyrimidine Nucleotides; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Survival Analysis; Treatment Outcome | 2005 |
The human equilibrative nucleoside transporter 1 mediates in vitro cytarabine sensitivity in childhood acute myeloid leukaemia.
Topics: Acute Disease; Antimetabolites, Antineoplastic; Cell Membrane; Child; Cytarabine; Drug Resistance, Neoplasm; Equilibrative Nucleoside Transporter 1; Gene Expression Profiling; Humans; Leukemia, Myeloid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 2005 |
Low incidence of sepsis due to viridans streptococci in a ten-year retrospective study of pediatric acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Incidence; Infant; Infant, Newborn; Infection Control; Leukemia, Myeloid; Male; Retrospective Studies; Sepsis; Streptococcal Infections; Survival Rate; Treatment Outcome; Viridans Streptococci | 2006 |
Immunological characterization and antibacterial function of persisting granulocytes in leukemic patients receiving pulse cytosine arabinoside-consolidation chemotherapy on days 1, 3, and 5.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bacterial Infections; Cytarabine; Drug Administration Schedule; Female; Granulocytes; Humans; Immunophenotyping; Leukemia, Myeloid; Male; Neutrophils; Time Factors | 2006 |
In vitro sensitivity and cross-resistance to deoxynucleoside analogs in childhood acute leukemia.
Topics: Acute Disease; Child; Cytarabine; Drug Resistance, Multiple; Drug Screening Assays, Antitumor; Humans; Leukemia; Nucleosides | 2006 |
Targeting Hsp90 by 17-AAG in leukemia cells: mechanisms for synergistic and antagonistic drug combinations with arsenic trioxide and Ara-C.
Topics: Acute Disease; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Benzoquinones; Cytarabine; DNA; Drug Administration Schedule; Drug Antagonism; Drug Screening Assays, Antitumor; Drug Synergism; Drug Therapy, Combination; G1 Phase; HeLa Cells; HSP90 Heat-Shock Proteins; Humans; Jurkat Cells; Lactams, Macrocyclic; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid; Oxides; Sensitivity and Specificity; Structure-Activity Relationship; Tumor Cells, Cultured | 2006 |
Unrelated cord blood transplantation after myeloablative conditioning in patients with acute leukemia aged between 50 and 55 years.
Topics: Acute Disease; Body Weight; Cord Blood Stem Cell Transplantation; Cytarabine; Female; Fetal Blood; Graft vs Host Disease; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Transplantation Conditioning | 2006 |
Extramedullary infiltration at diagnosis and prognosis in children with acute myelogenous leukemia.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone and Bones; Central Nervous System; Child; Child, Preschool; Cytarabine; Disease-Free Survival; Etoposide; Female; Follow-Up Studies; Gingiva; Humans; Hydrocortisone; Idarubicin; Infant; Infant, Newborn; Japan; Kaplan-Meier Estimate; Leukemia, Myeloid; Leukemic Infiltration; Male; Methotrexate; Orbit; Prognosis; Remission Induction; Sarcoma, Myeloid; Skin; Testis | 2007 |
Conversion disorder with convulsion and motor deficit mimicking the adverse effects of high-dose Ara-C treatment in a posttransplant acute myeloid leukemia patient: a case report and review of the literature.
Topics: Acute Disease; Adult; Antimetabolites, Antineoplastic; Bone Marrow Transplantation; Conversion Disorder; Cytarabine; Diagnosis, Differential; Female; Humans; Leukemia, Myeloid; Neurotoxicity Syndromes; Psychomotor Performance; Seizures | 2004 |
Improved outcome in childhood acute myeloid leukemia in Singapore with the MRC AML 10 protocol.
Topics: Acute Disease; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Cytarabine; Daunorubicin; Developing Countries; Disease-Free Survival; Drug Evaluation; Etoposide; Female; Gastrointestinal Diseases; Heart Diseases; Hematologic Diseases; Humans; Infant; Infections; Kaplan-Meier Estimate; Leukemia, Myeloid; Male; Mercaptopurine; Methotrexate; Mitoxantrone; Prednisone; Remission Induction; Retrospective Studies; Singapore; Survival Analysis; Thioguanine; Treatment Outcome; Vincristine | 2007 |
Trp53 loss during in vitro selection contributes to acquired Ara-C resistance in acute myeloid leukemia.
Topics: Acute Disease; Animals; Antimetabolites, Antineoplastic; Base Sequence; Cell Line; Cyclin-Dependent Kinase Inhibitor p21; Cytarabine; DNA Primers; Down-Regulation; Drug Resistance, Neoplasm; Exons; Humans; Leukemia, Myeloid; Mice; Reverse Transcriptase Polymerase Chain Reaction; RNA Splicing; RNA, Messenger; Tumor Suppressor Protein p53 | 2006 |
An antecedent diagnosis of refractory anemia with excess blasts has no prognostic relevance in acute myeloid leukemia of older adult patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Anemia, Refractory, with Excess of Blasts; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Combined Modality Therapy; Cytarabine; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Prognosis; Remission Induction; Stem Cell Transplantation; Vidarabine | 2006 |
Core binding factor acute myeloid leukemia.
Topics: Acute Disease; Core Binding Factors; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid; Neoplasm, Residual; Prognosis; Reverse Transcriptase Polymerase Chain Reaction; Sensitivity and Specificity; Treatment Outcome | 2006 |
Increased expression of insulin-like growth factor i is associated with Ara-C resistance in leukemia.
Topics: Acute Disease; Adult; Aged; Apoptosis; Cytarabine; Drug Resistance, Neoplasm; Female; Gene Expression Profiling; Humans; Insulin-Like Growth Factor I; K562 Cells; Leukemia, Myeloid; Male; Middle Aged; Oligonucleotide Array Sequence Analysis; Oncogene Protein v-akt; Receptor, IGF Type 1; Suramin; Up-Regulation | 2006 |
Clearance of leukaemic blasts from peripheral blood during standard induction treatment predicts the bone marrow response in acute myeloid leukaemia: a pilot study.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Bone Marrow; Cytarabine; Female; Flow Cytometry; Humans; Idarubicin; Leukemia, Myeloid; Leukocyte Count; Male; Middle Aged; Pilot Projects; Prognosis; Remission Induction | 2006 |
Peripheral neuropathy caused by high-dose cytosine arabinoside treatment in a patient with acute myeloid leukemia.
Topics: Acute Disease; Cytarabine; Humans; Leukemia, Myeloid; Male; Middle Aged; Peripheral Nervous System Diseases | 2006 |
Multifocal necrotizing leukoencephalopathy: An unusual complication of acute leukemia.
Topics: Acute Disease; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Humans; Leukemia-Lymphoma, Adult T-Cell; Leukoencephalopathy, Progressive Multifocal; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Necrosis; Vincristine | 2006 |
[An abdominal Burkitt's lymphoma in acute phase. Case report].
Topics: Acute Disease; Adolescent; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Appendicitis; Burkitt Lymphoma; Cytarabine; Diagnosis, Differential; Humans; Ileal Neoplasms; Immunohistochemistry; Liver Neoplasms; Male; Methotrexate; Radiography, Abdominal; Remission Induction; Tomography, X-Ray Computed; Ultrasonography | 2006 |
Cross-resistance to cytosine arabinoside in human acute myeloid leukemia cells selected for resistance to vincristine.
Topics: Acute Disease; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytarabine; Drug Resistance, Neoplasm; Gene Expression; Humans; Leukemia, Myeloid; Selection, Genetic; Tumor Cells, Cultured; Vincristine | 2006 |
Central line-related bacteraemia due to Roseomonas mucosa in a neutropenic patient with acute myeloid leukaemia in Piraeus, Greece.
Topics: Acute Disease; Adult; Amikacin; Anti-Bacterial Agents; Antimetabolites, Antineoplastic; Antineoplastic Agents; Bacteremia; Base Sequence; Catheterization, Central Venous; Cytarabine; Humans; Leukemia, Myeloid; Male; Methylobacteriaceae; Molecular Sequence Data; Neutropenia; Penicillanic Acid; Phylogeny; Piperacillin; Piperacillin, Tazobactam Drug Combination; RNA, Bacterial; RNA, Ribosomal, 16S; Vidarabine | 2006 |
Prognostic significance of WT1 gene expression in pediatric acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brazil; Child; Child, Preschool; Chromosome Inversion; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Cytarabine; Daunorubicin; Etoposide; Female; Follow-Up Studies; Gene Expression Regulation, Leukemic; Genes, Wilms Tumor; Humans; Infant; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Male; Neoplasm Proteins; Prognosis; Proportional Hazards Models; Reverse Transcriptase Polymerase Chain Reaction; Survival Analysis; Translocation, Genetic; WT1 Proteins | 2007 |
Zygomycosis in the immunocompromised patient: a case report.
Topics: Absidia; Acute Disease; Aerosols; Amphotericin B; Amsacrine; Antibiotic Prophylaxis; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Daunorubicin; Debridement; Drug Resistance, Fungal; Drug Resistance, Neoplasm; Etoposide; Fluconazole; Humans; Immunocompromised Host; Leukemia; Liposomes; Middle Aged; Mucormycosis; Sinusitis; Tomography, X-Ray Computed | 2006 |
Induction of remission of relapsed acute myeloid leukemia after unrelated donor cord blood transplantation by concomitant low-dose cytarabine and calcitriol in adults.
Topics: Aclarubicin; Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Calcitriol; Cord Blood Stem Cell Transplantation; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myeloid; Middle Aged; Recurrence; Remission Induction; Reverse Transcriptase Polymerase Chain Reaction | 2006 |
Cytotoxic activity of the third-generation bisphosphonate zoledronic acid in acute myeloid leukemia.
Topics: Acute Disease; Aged; Antineoplastic Agents; Bone Marrow Cells; Caspase 3; Cell Proliferation; Cytarabine; Diphosphonates; Drug Screening Assays, Antitumor; Drug Therapy, Combination; Female; Flow Cytometry; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; HL-60 Cells; Humans; Imidazoles; Leukemia, Myeloid; Male; Middle Aged; Zoledronic Acid | 2007 |
De novo acute myeloid leukemia in adults younger than 60 years of age: socioeconomic aspects and treatment results in a Brazilian university center.
Topics: Academic Medical Centers; Acute Disease; Brazil; Cytarabine; Disease-Free Survival; Humans; Leukemia, Myeloid; Middle Aged; Patient Selection; Remission Induction; Retrospective Studies; Socioeconomic Factors; Survival Rate | 2006 |
Effect of gemtuzumab ozogamicin on acute myeloid leukemia blast cells in vitro, as a single agent and combined with other cytotoxic cells.
Topics: Acute Disease; Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Proliferation; Cytarabine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Resistance, Multiple; Etoposide; Gemtuzumab; Humans; Leukemia, Myeloid; Tumor Cells, Cultured | 2006 |
[Bulky lymphadenopathy in acute myeloid leukemia with inv (16) (p13q22): a case report].
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Chromosome Inversion; Chromosomes, Human, Pair 16; Cytarabine; Humans; Idarubicin; Leukemia, Myeloid; Lymphatic Diseases; Male; Neoplasm, Residual; Prognosis | 2006 |
Growth inhibition and induction of apoptosis in acute myeloid leukemia cells by new indolinone derivatives targeting fibroblast growth factor, platelet-derived growth factor, and vascular endothelial growth factor receptors.
Topics: Acute Disease; Apoptosis; Cell Growth Processes; Cell Line, Tumor; Cytarabine; Humans; Indoles; Leukemia, Myeloid; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Receptor Protein-Tyrosine Kinases; Receptors, Fibroblast Growth Factor; Receptors, Platelet-Derived Growth Factor; Receptors, Vascular Endothelial Growth Factor; Signal Transduction | 2006 |
t(8;21) (q22;q22) acute myelogenous leukemia in Mexico: a single institution experience.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Combined Modality Therapy; Core Binding Factor Alpha 2 Subunit; Cytarabine; Disease-Free Survival; Doxorubicin; Female; Humans; Infant; Kaplan-Meier Estimate; Leukemia, Myeloid; Male; Mexico; Middle Aged; Oncogene Proteins, Fusion; Peripheral Blood Stem Cell Transplantation; Prevalence; Prospective Studies; Remission Induction; RUNX1 Translocation Partner 1 Protein; Salvage Therapy; Translocation, Genetic; Transplantation, Autologous; Transplantation, Homologous; Treatment Outcome | 2006 |
Long-term follow-up of autologous peripheral blood stem cell transplantation in the treatment of a patient with acute panmyelosis with myelofibrosis.
Topics: Acute Disease; Anemia, Refractory; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Erythropoietin; Etoposide; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Male; Methotrexate; Middle Aged; Mitoxantrone; Peripheral Blood Stem Cell Transplantation; Postoperative Complications; Primary Myelofibrosis; Recombinant Proteins; Transplantation Conditioning; Transplantation, Autologous; Whole-Body Irradiation | 2006 |
Levels of soluble HLA-I and beta2M in patients with acute myeloid leukemia and advanced myelodysplastic syndrome: association with clinical behavior and outcome of induction therapy.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; beta 2-Microglobulin; Biomarkers, Tumor; Cytarabine; Disease Progression; Female; HLA Antigens; Humans; Idarubicin; Kaplan-Meier Estimate; Leukemia, Myeloid; Male; Middle Aged; Myelodysplastic Syndromes; Neoplasm Proteins; Predictive Value of Tests; Proportional Hazards Models; Remission Induction; Solubility; Topotecan; Treatment Outcome; Vidarabine | 2007 |
The haematopoietic cell transplantation comorbidity index score is predictive of early death and survival in patients over 60 years of age receiving induction therapy for acute myeloid leukaemia.
Topics: Acute Disease; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Epidemiologic Methods; Female; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Prognosis; Severity of Illness Index; Treatment Outcome | 2007 |
Improved outcome after relapse in children with acute myeloid leukaemia.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Cytogenetics; Disease-Free Survival; Female; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Male; Recurrence; Remission Induction; Statistics, Nonparametric; Stem Cell Transplantation; Survival Rate; Sweden; Treatment Outcome; Vidarabine | 2007 |
Therapy for elderly patients with acute myeloid leukemia: a problem in search of solutions.
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Myeloid; Male; Treatment Outcome | 2007 |
Acute encephalopathy and cerebral vasospasm after multiagent chemotherapy including PEG-asparaginase and intrathecal cytarabine for the treatment of acute lymphoblastic leukemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Brain; Brain Diseases; Burkitt Lymphoma; Child; Cytarabine; Female; Follow-Up Studies; Humans; Injections, Spinal; Magnetic Resonance Angiography; Polyethylene Glycols; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sensitivity and Specificity; Treatment Outcome; Vasospasm, Intracranial | 2007 |
Expression of multidrug resistance (MDR) proteins and in vitro drug resistance in acute leukemias.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Cell Survival; Child; Child, Preschool; Coloring Agents; Cytarabine; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Infant; Inhibitory Concentration 50; Leukemia; Leukemia, Myeloid; Male; Methylphenazonium Methosulfate; Middle Aged; Neoplasm Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Staining and Labeling; Tetrazolium Salts; Thiazoles; Treatment Outcome; Tumor Cells, Cultured | 2007 |
An unusual cause of unilateral pleural effusion in the setting of aortic stenosis: acute myeloid leukemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Aortic Valve Stenosis; Cytarabine; Fatal Outcome; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Liver Diseases; Male; Middle Aged; Mycoses; Pleural Effusion; Treatment Outcome; Vidarabine | 2007 |
FLT3 tyrosine kinase domain mutations are biologically distinct from and have a significantly more favorable prognosis than FLT3 internal tandem duplications in patients with acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Alleles; Amino Acid Substitution; Antimetabolites, Antineoplastic; Cytarabine; DNA Mutational Analysis; Female; fms-Like Tyrosine Kinase 3; Follow-Up Studies; Gene Duplication; Humans; In Situ Hybridization, Fluorescence; Leukemia, Myeloid; Male; Middle Aged; Mutation; Prognosis; Survival Rate; Tandem Repeat Sequences; Treatment Outcome | 2007 |
Monitoring of minimal residual disease in adult acute myeloid leukemia using peripheral blood as an alternative source to bone marrow.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Cells; Bone Marrow Examination; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Flow Cytometry; Humans; Idarubicin; Kaplan-Meier Estimate; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Neoplasm, Residual; Organ Specificity; Randomized Controlled Trials as Topic; Remission Induction; Survival Analysis; Treatment Outcome | 2007 |
Autocrine insulin-like growth factor-I signaling promotes growth and survival of human acute myeloid leukemia cells via the phosphoinositide 3-kinase/Akt pathway.
Topics: Acute Disease; Antibodies; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Autocrine Communication; Cell Division; Cell Line, Tumor; Cytarabine; Down-Regulation; Etoposide; Humans; Insulin-Like Growth Factor I; Leukemia, Myeloid; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1; Signal Transduction | 2007 |
Biphenotypic acute leukaemia: a case series.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Female; Humans; Immunophenotyping; Leukemia; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome; Vincristine | 2007 |
Pseudomembranous necrotizing tracheobronchitis caused by Aspergillus spp--contribution of one case with acute myeloid leukemia.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Aspergillosis; Aspergillus; Bronchitis; Cytarabine; Etoposide; Fatal Outcome; Humans; Idarubicin; Immunocompromised Host; Leukemia, Myeloid; Lung Diseases, Fungal; Male; Necrosis; Opportunistic Infections; Radiography, Thoracic; Tracheitis | 2006 |
The criteria for bone marrow recovery post-myelosuppressive therapy for acute myelogenous leukemia: a quantitative study.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Blood Cell Count; Bone Marrow; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Female; Humans; Image Processing, Computer-Assisted; Immunophenotyping; Leukemia, Myeloid; Male; Middle Aged; Recovery of Function; Remission Induction; Time Factors | 2007 |
Cytarabine-related lung infiltrates on high resolution computerized tomography: a possible complication with benign outcome in leukemic patients.
Topics: Acute Disease; Aged; Antimetabolites, Antineoplastic; Blood Gas Analysis; Bone Marrow Transplantation; Cytarabine; Dyspnea; Female; Fever; Humans; Hypoxia; Leukemia, Myeloid; Lung Diseases; Male; Middle Aged; Tomography, X-Ray Computed; Treatment Outcome | 2007 |
Synergistic antileukemic effects between ABT-869 and chemotherapy involve downregulation of cell cycle-regulated genes and c-Mos-mediated MAPK pathway.
Topics: Acute Disease; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Cycle Proteins; Cytarabine; Down-Regulation; Doxorubicin; Drug Synergism; Drug Therapy, Combination; Gene Expression Profiling; Humans; Indazoles; Leukemia, Myeloid; Mice; Mice, SCID; Mitogen-Activated Protein Kinases; Phenylurea Compounds; Proto-Oncogene Proteins c-mos; Receptor Protein-Tyrosine Kinases; RNA, Small Interfering; Signal Transduction; Transplantation, Heterologous | 2008 |
The role of the proto-oncogene ETS2 in acute megakaryocytic leukemia biology and therapy.
Topics: Acute Disease; Cell Differentiation; Child; Chromosomes, Human, Pair 21; Cytarabine; Daunorubicin; Down Syndrome; Drug Resistance, Neoplasm; Erythroid Precursor Cells; Erythropoiesis; GATA1 Transcription Factor; Gene Dosage; Gene Expression Regulation, Leukemic; Genetic Predisposition to Disease; Humans; K562 Cells; Leukemia, Megakaryoblastic, Acute; Leukemia, Myeloid; Megakaryocytes; Neoplasm Proteins; Proto-Oncogene Mas; Proto-Oncogene Protein c-ets-2; Thrombopoiesis | 2008 |
Outcome of BEAM-autologous and BEAM-alemtuzumab allogeneic transplantation in relapsed advanced stage follicular lymphoma.
Topics: Acute Disease; Adult; Aged; Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cytarabine; Etoposide; Female; Follow-Up Studies; Graft Survival; Graft vs Host Disease; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Histocompatibility Testing; Humans; Lymphoma, Follicular; Male; Melphalan; Middle Aged; Retrospective Studies; Transplantation Chimera; Transplantation Conditioning; Treatment Outcome | 2008 |
[The assay of intracelluar cytidine deaminase activity and its clinical significance in patient with acute leukemia].
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Cytarabine; Cytidine Deaminase; Drug Resistance, Neoplasm; Female; Humans; Intracellular Fluid; Leukemia; Male; Middle Aged; Young Adult | 2008 |
Treatment of acute non-lymphoblastic leukaemia in elderly patients.
Topics: Acute Disease; Aged; Cytarabine; Humans; Leukemia | 1984 |
High-dose neuroleptics for acute brain failure after intensive chemotherapy for acute leukemia.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Antipsychotic Agents; Asparaginase; Cytarabine; Humans; Leucovorin; Leukemia, Lymphoid; Male; Methotrexate; Substance-Related Disorders | 1984 |
[Immunotherapy of acute blastic leukemia in adults].
Topics: Acute Disease; Adult; BCG Vaccine; Cytarabine; Doxorubicin; Hematopoietic Stem Cells; Humans; Immunotherapy; Leukemia; Thioguanine | 1981 |
Phase I study on 5-aza-2'-deoxycytidine in children with acute leukemia.
Topics: Acute Disease; Adolescent; Antineoplastic Agents; Azacitidine; Child; Child, Preschool; Cytarabine; Decitabine; Dose-Response Relationship, Drug; Drug Evaluation; Hematopoietic System; Humans; Leukemia; Male | 1981 |
[Comparative evaluation of combined chemotherapeutic regimens in acute non-lymphocytic leukemia].
Topics: Aclarubicin; Acute Disease; Adult; Age Factors; Ancitabine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Mercaptopurine; Middle Aged; Naphthacenes; Prednisolone | 1983 |
Results of intrathecal prophylaxis and treatment of CNS involvement in adult acute leukaemias.
Topics: Acute Disease; Brain Neoplasms; Cytarabine; Drug Administration Schedule; Humans; Injections, Spinal; Leukemia; Methotrexate; Prednisolone | 1984 |
[Initial results in allo- and auto-bone marrow transplantation in acute leukemia in East Germany].
Topics: Acute Disease; Adolescent; Adult; Body Weight; Bone Marrow Transplantation; Combined Modality Therapy; Cyclophosphamide; Cystitis; Cytarabine; Drug Therapy, Combination; Female; Germany, East; Humans; Leukemia; Male; Methotrexate; Mycoses; Stomatitis; Transplantation, Autologous; Transplantation, Homologous; Vincristine; Whole-Body Irradiation | 1984 |
Design of controlled clinical trials: use of historical controls.
Topics: Acute Disease; Adolescent; Adult; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Glioma; Humans; Leukemia; Male; Plicamycin; Random Allocation; Uracil; Vincristine | 1982 |
High-dose cytosine arabinoside therapy for refractory leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Bone Marrow Diseases; Cerebellar Ataxia; Cognition Disorders; Conjunctivitis; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Eruptions; Hemorrhage; Humans; Leukemia; Middle Aged | 1983 |
[Lung survival or healing? Description of a case of acute non-lymphoblastic leukosis].
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Follow-Up Studies; Humans; Leukemia; Male; Methotrexate; Thioguanine | 1984 |
High-dose cytosine arabinoside and m-AMSA is effective therapy in relapsed acute nonlymphocytic leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Aminoacridines; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Drug Eruptions; Hemorrhage; Humans; Leukemia; Middle Aged; Nausea; Recurrence; Vomiting | 1984 |
Prognostic factors in adult patients with acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Chromosome Aberrations; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Prednisolone; Prognosis; Vincristine; Zinostatin | 1983 |
Human serum megakaryocyte colony-stimulating activity increases in response to intensive cytotoxic chemotherapy.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cells, Cultured; Colony-Stimulating Factors; Cytarabine; Daunorubicin; Humans; Leukemia; Megakaryocytes; Platelet Count; Thioguanine | 1984 |
A comparison of bone marrow transplantation with maintenance chemotherapy for patients with acute nonlymphoblastic leukemia in first complete remission.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transplantation; Cytarabine; Female; Graft vs Host Disease; Hematologic Diseases; Humans; Leukemia; Male; Recurrence; Thioguanine | 1984 |
[Pharmacokinetics of intrathecal chemotherapy and clinical problems].
Topics: Acute Disease; Blood-Brain Barrier; Cytarabine; Humans; Infusions, Parenteral; Injections, Spinal; Kinetics; Leukemia; Meningeal Neoplasms; Methotrexate; Thiotepa | 1984 |
[ACNP therapy for DCMP-resistant acute leukemia (author's transl)].
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Agents; Cytarabine; Doxorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisolone; Zinostatin | 1981 |
[Characteristics of the electrophoretic mobility of blasts from acute non-lymphoid leukemias].
Topics: Acute Disease; Adult; Aged; Cytarabine; Electrophoresis; Female; Humans; Leukemia; Leukocytes; Male; Middle Aged | 1984 |
Low dose cytosine arabinoside used to induce remission in acute myelofibrosis.
Topics: Acute Disease; Cytarabine; Humans; Male; Middle Aged; Primary Myelofibrosis | 1984 |
Probable cures of adult acute leukemia using short term intensive investigational chemotherapy.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Administration Schedule; Humans; Leukemia; Vincristine | 1984 |
Two-cycle timed-sequential chemotherapy for adult acute nonlymphocytic leukemia.
Topics: Acute Disease; Adult; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Humans; Leukemia; Recurrence | 1984 |
Assessment of the drug sensitivity of acute nonlymphocytic leukaemia using the in vitro clonogenic assay.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cell Survival; Colony-Forming Units Assay; Cytarabine; Daunorubicin; Doxorubicin; Humans; Leukemia; Thioguanine; Tumor Stem Cell Assay | 1984 |
[High-dose cytosine arabinoside therapy in refractory acute leukemia].
Topics: Acute Disease; Adult; Aged; Cytarabine; Drug Administration Schedule; Female; Humans; Leukemia; Male; Middle Aged | 1984 |
High-dose cytosine arabinoside therapy in acute non-lymphocytic leukemia.
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Humans; Leukemia; Middle Aged | 1984 |
Inhibition of DNA synthesis by cytosine arabinoside: relation to response of acute non-lymphocytic leukemia to remission induction therapy and to stage of the disease.
Topics: Acute Disease; Aged; Cytarabine; DNA, Neoplasm; Humans; In Vitro Techniques; Interphase; Leukemia; Neoplasm Staging | 1984 |
[Treatment of acute leukemia].
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Deoxycytidine Monophosphate; Humans; Leukemia; Mercaptopurine; Prednisolone | 1984 |
Proliferation kinetics and prediction of chemotherapeutic effect in adult acute leukemia according to the FAB classification.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cell Division; Cytarabine; Daunorubicin; Female; Humans; Kinetics; Leukemia; Male; Mercaptopurine; Middle Aged; Neoplastic Stem Cells; Prednisolone; Prognosis | 1984 |
[Acute pancreatitis during the treatment of BH-AC AMP regimen for acute non-lymphocytic leukemia].
Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia; Male; Mercaptopurine; Middle Aged; Naphthacenes; Pancreatitis; Prednisolone | 1984 |
Recognition of drug resistance during remission induction therapy for acute non-lymphocytic leukemia: utility of day 6 bone marrow biopsy.
Topics: Acute Disease; Aged; Antibiotics, Antineoplastic; Bone Marrow Examination; Cytarabine; Drug Resistance; Drug Therapy, Combination; Humans; Leukemia; Naphthacenes | 1983 |
Therapy of secondary acute nonlymphocytic leukemia.
Topics: Acute Disease; Antibiotics, Antineoplastic; Cytarabine; Drug Therapy, Combination; Humans; Leukemia; Naphthacenes | 1983 |
Pericarditis as presenting manifestation of acute nonlymphocytic leukemia in a young child.
Topics: Acute Disease; Child, Preschool; Cytarabine; Diagnosis, Differential; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Pericarditis; Thioguanine | 1983 |
[Changes of therapy results in acute leukemia under different treatment schedules with special reference to gnotobiotic measures].
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents; Asparaginase; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Patient Isolation; Prednisolone; Thioguanine; Vincristine | 1983 |
[VP 16-213 in the treatment of acute leukemia in childhood].
Topics: Acute Disease; Adolescent; Antineoplastic Agents; Child; Child, Preschool; Cytarabine; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Humans; Leukemia; Leukemia, Lymphoid; Male; Podophyllotoxin | 1983 |
[Aclacinomycin A and behenoyl ara-C combination chemotherapy for untreated acute non-lymphocytic leukemia].
Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged; Naphthacenes | 1983 |
Long term follow-up of remission patients in adult acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Female; Follow-Up Studies; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Prognosis; Time Factors; Vincristine | 1983 |
Therapeutic activity of 4-demethoxydauno-rubicin (idarubicin) in adult acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Daunorubicin; Drug Evaluation; Female; Humans; Idarubicin; Leukemia; Male; Middle Aged; Time Factors | 1983 |
Relationship between the per cent of marrow cells in S phase and the outcome of remission-induction therapy for acute nonlymphocytic leukaemia.
Topics: Acute Disease; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Female; Humans; Interphase; Leukemia; Male; Middle Aged; Naphthacenes; Thioguanine | 1984 |
Treatment of acute myeloid leukemia with a combination of intensive induction chemotherapy, early consolidation, splenectomy and long-term maintenance chemotherapy.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Doxorubicin; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Pancytopenia; Recurrence; Splenectomy; Time Factors; Vincristine | 1984 |
[Central nervous system involvement in adult acute leukemia].
Topics: Acute Disease; Adult; Aged; Brain Neoplasms; Combined Modality Therapy; Cytarabine; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged | 1984 |
The relationship between growth in agar, karyotype and prognosis in acute leukaemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells; Cells, Cultured; Chromosome Aberrations; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Karyotyping; Leukemia; Leukemia, Lymphoid; Male; Middle Aged; Neoplastic Stem Cells; Prednisolone; Prednisone; Prognosis; Thioguanine; Vincristine | 1984 |
High dose araC in acute nonlymphocytic leukemia complicating Hodgkin's disease.
Topics: Acute Disease; Cytarabine; Dose-Response Relationship, Drug; Hodgkin Disease; Humans; Leukemia; Male; Middle Aged | 1983 |
Progressive cutaneous herpes simplex infection in acute myeloblastic leukemia. Successful treatment with interferon and cytarabine.
Topics: Acute Disease; Adult; Appendectomy; Appendicitis; Cytarabine; Drug Therapy, Combination; Herpes Simplex; Humans; Interferon Type I; Leukemia, Myeloid, Acute; Male; Skin; Skin Diseases, Infectious; Surgical Wound Infection | 1984 |
Prediction of response to chemotherapy in acute leukemia by in vitro drug sensitivity testing on leukemic stem cells.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cell Survival; Cells, Cultured; Colony-Forming Units Assay; Cytarabine; Daunorubicin; DNA Replication; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisolone; Thioguanine | 1984 |
Continuous infusion high-dose cytosine arabinoside in refractory childhood leukemia.
Topics: Acute Disease; Adolescent; Arabinofuranosylcytosine Triphosphate; Bone Marrow; Child; Child, Preschool; Cytarabine; Deoxycytosine Nucleotides; Drug Administration Schedule; Humans; Infusions, Parenteral; Kinetics; Leukemia; Leukemia, Lymphoid | 1984 |
In vitro assessment of drug sensitivity in acute nonlymphocytic leukemia.
Topics: Acute Disease; Antibiotics, Antineoplastic; Antineoplastic Agents; Biological Transport; Colony-Forming Units Assay; Cytarabine; Drug Evaluation, Preclinical; Humans; Leukemia; Naphthacenes; Prognosis; Tumor Stem Cell Assay | 1984 |
Aclarubicin in the treatment of acute nonlymphocytic leukemia refractory to treatment with daunorubicin and cytarabine: a phase II trial.
Topics: Aclarubicin; Acute Disease; Adult; Aged; Antibiotics, Antineoplastic; Cytarabine; Daunorubicin; Drug Evaluation; Heart; Humans; Leukemia; Leukopenia; Middle Aged; Naphthacenes; Prospective Studies; Thrombocytopenia | 1984 |
[Sunrabin for injection].
Topics: Acute Disease; Adult; Animals; Antineoplastic Agents; Cytarabine; Humans; Injections; Lethal Dose 50; Leukemia; Mice; Rats | 1983 |
The clonogenic assay as a reproducible in vitro system to study predictive parameters of treatment outcome in acute nonlymphoblastic leukemia.
Topics: Acute Disease; Bone Marrow Cells; Clone Cells; Colony-Forming Units Assay; Cytarabine; Doxorubicin; Drug Evaluation, Preclinical; Drug Resistance; Humans; Leukemia; Prognosis; Recurrence | 1983 |
A rapid in vitro drug-sensitivity assay in acute nonlymphocytic leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Cells, Cultured; Cytarabine; Daunorubicin; Drug Evaluation, Preclinical; Female; Hematopoietic Stem Cells; Humans; Leukemia; Male; Middle Aged; Sulfates; Sulfur Radioisotopes | 1983 |
[Prediction of the response of patients with acute leukemia to chemotherapeutic agents by tritiated thymidine uptake by leukocytes].
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia; Leukocytes; Male; Middle Aged; Thymidine; Tritium | 1983 |
Cerebellar degeneration caused by high-dose cytosine arabinoside: a clinicopathological study.
Topics: Acute Disease; Adolescent; Adult; Aged; Cerebellar Ataxia; Cerebellar Cortex; Cerebellar Nuclei; Cerebellum; Cytarabine; Dose-Response Relationship, Drug; Eye Movements; Female; Humans; Leukemia; Male; Middle Aged; Nerve Degeneration; Nystagmus, Pathologic; Purkinje Cells | 1983 |
Alteration of the pharmacokinetics of high-dose ara-C by its metabolite, high ara-U in patients with acute leukemia.
Topics: Acute Disease; Arabinofuranosyluracil; Chromatography, High Pressure Liquid; Cytarabine; Cytidine Deaminase; Dose-Response Relationship, Drug; Humans; Infusions, Parenteral; Kinetics; Leukemia; Models, Biological; Nucleoside Deaminases; Radioimmunoassay; Time Factors; Uridine | 1983 |
[Leukemic colony (L-CFU) formation in vitro: clinical correlations of the in vitro growth pattern of L-CFU and drug sensitivity in acute leukemia].
Topics: Acute Disease; Cell Division; Colony-Forming Units Assay; Cytarabine; Daunorubicin; Deoxycytidine Monophosphate; Humans; Leukemia; Tumor Stem Cell Assay | 1983 |
Cytosine arabinoside transport by human leukaemic cells.
Topics: Acute Disease; Adolescent; Adult; Aged; Biological Transport; Cell Membrane; Child; Child, Preschool; Cytarabine; Deoxycytidine; Humans; Infant; Kinetics; Leukemia; Leukocytes; Middle Aged; Phloretin; Thioinosine | 1983 |
Leukemic cell differentiation in vivo and in vitro: arrest of proliferation parallels the differentiation induced by the antileukemic drug Harringtonine.
Topics: Acute Disease; Adult; Alkaloids; Cell Differentiation; Cell Division; Cell Line; Clone Cells; Cytarabine; Female; Harringtonines; Humans; Leukemia; Male; Middle Aged; Monocytes; Thioguanine | 1984 |
Thymidine as a kinetic and biochemical modulator of 1-beta-D-arabinofuranosylcytosine in human acute nonlymphocytic leukemia.
Topics: Acute Disease; Adult; Cytarabine; Deoxycytidine; Female; Humans; Interphase; Kinetics; Leukemia; Male; Middle Aged; Phosphorylation; Thymidine | 1984 |
High-dose cytosine arabinoside for acute nonlymphocytic leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia; Liver; Male | 1984 |
Treatment of poor risk acute leukemia with sequential high-dose ARA-C and asparaginase.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cell Transformation, Neoplastic; Child; Cytarabine; Drug Resistance; Female; Humans; Leukemia; Male; Middle Aged | 1984 |
Differentiation versus cytoreduction during remission induction in acute nonlymphoblastic leukemia treated with sequential high-dose ara-C and asparaginase.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow; Cell Differentiation; Cytarabine; Hematopoietic Stem Cells; Humans; Leukemia; Leukocyte Count; Male; Middle Aged | 1984 |
Acute cerebellar dysfunction with high-dose Ara-C therapy.
Topics: Acute Disease; Adult; Cerebellar Diseases; Cytarabine; Humans; Leukemia | 1984 |
Successful treatment of meningeal leukemia using systemic high-dose cytosine arabinoside.
Topics: Acute Disease; Adult; Aged; Cytarabine; Drug Evaluation; Female; Humans; Injections, Intravenous; Leukemia; Male; Meningeal Neoplasms; Middle Aged; Recurrence | 1984 |
The use of intermediate dose cytosine arabinoside (ID Ara-C) in the treatment of acute non-lymphocytic leukaemia in relapse.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Doxorubicin; Half-Life; Humans; Leukemia; Middle Aged; Vincristine | 1984 |
TdT-positive acute leukemia with monocytoid characteristics: clinical, cytochemical, cytogenetic, and immunologic findings.
Topics: Acute Disease; Adult; Aged; Antibodies, Monoclonal; Cell Membrane; Chromosome Aberrations; Cytarabine; Daunorubicin; DNA Nucleotidylexotransferase; DNA Nucleotidyltransferases; Female; Histocytochemistry; Humans; Leukemia; Male; Middle Aged; Monocytes; Neoplastic Stem Cells; Phenotype; Prednisone; Vincristine | 1984 |
[Acute adult leukemia. Therapeutic options including supportive measures].
Topics: Acute Disease; Adrenal Cortex Hormones; Adult; Asparaginase; Cytarabine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Humans; Leukemia; Methotrexate; Remission, Spontaneous; Vincristine | 1980 |
High remission induction (traditional sino-western HOAP) regimen for acute nonlymphocytic leukemia.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Agents; Child; Cytarabine; Drug Therapy, Combination; Female; Harringtonines; Homoharringtonine; Humans; Leukemia; Male; Medicine, Chinese Traditional; Middle Aged; Prednisone; Vincristine | 1980 |
Long-term disease-free survival in acute nonlymphocytic leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Cytarabine; Daunorubicin; Female; Humans; Leukemia; Long-Term Care; Male; Middle Aged; Prednisone; Recurrence; Thioguanine | 1981 |
Remission-induction, consolidation and maintenance therapy by AVA protocol in acute nonlymphoblastic leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Child; Child, Preschool; Cytarabine; Doxorubicin; Female; Humans; Leukemia; Male; Middle Aged; Vincristine | 1982 |
Adverse effects of aneuploidy on the outcome of remission induction therapy for acute nonlymphocytic leukaemia: analysis of types of treatment failure.
Topics: Acute Disease; Aneuploidy; Bone Marrow; Cytarabine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Female; Humans; Karyotyping; Leukemia; Male; Metaphase; Middle Aged; Prognosis | 1983 |
Posttransfusion hepatitis in acute nonlymphocytic leukemia: lack of a beneficial influence.
Topics: Acute Disease; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Hepatitis; Humans; Leukemia; Male; Prognosis; Transfusion Reaction | 1983 |
Therapy of secondary acute nonlymphocytic leukemia with cytarabine.
Topics: Acute Disease; Adult; Aged; Chromosome Aberrations; Cytarabine; Humans; Leukemia; Middle Aged | 1983 |
Cell kinetic responses in childhood acute nonlymphocytic leukemia during high-dose therapy with cytosine arabinoside.
Topics: Acute Disease; Adolescent; Bone Marrow; Bone Marrow Cells; Cell Division; Child; Child, Preschool; Cytarabine; DNA; Dose-Response Relationship, Drug; Female; Humans; Kinetics; Leukemia; Male | 1983 |
Pharmacokinetics of N4-behenoyl-1-beta-D-arabinofuranosylcytosine in patients with acute leukemia.
Topics: Acute Disease; Adult; Antineoplastic Agents; Arabinofuranosyluracil; Bone Marrow; Child; Child, Preschool; Chromatography, High Pressure Liquid; Cytarabine; Erythrocytes; Gas Chromatography-Mass Spectrometry; Humans; Infant; Infusions, Parenteral; Kinetics; Leukemia; Middle Aged; Time Factors | 1983 |
High-dose cytarabine in acute leukemia: toxicity and pharmacokinetics.
Topics: Acute Disease; Adolescent; Adult; Cytarabine; Cytidine Deaminase; Female; Half-Life; Humans; Kinetics; Leukemia; Leukocyte Count; Male; Middle Aged; Nausea; Nucleoside Deaminases; Vomiting | 1983 |
Does treatment with ARA-C in low dosage cause differentiation of leukemic cells?
Topics: Acute Disease; Aged; Cell Differentiation; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia | 1983 |
Central nervous system toxicity of high-dose cytosine arabinoside.
Topics: Acute Disease; Adult; Aged; Central Nervous System; Cerebellum; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged | 1983 |
[Therapeutic results of DCMP therapy (2M-80) in acute non-lymphocytic leukemia--the relationship between the residual leukemic cells and duration of remission].
Topics: Acute Disease; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Humans; Leukemia; Mercaptopurine; Middle Aged; Prednisolone | 1982 |
Treatment of acute leukemia in relapse with 4'(9-acridinylamino) methanesulfon-m-anisidide (AMSA) in combination with cytosine arabinoside and thioguanine.
Topics: Acute Disease; Adolescent; Adult; Aged; Aminoacridines; Amsacrine; Antineoplastic Agents; Chemical and Drug Induced Liver Injury; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Middle Aged; Neoplasm Recurrence, Local; Thioguanine | 1981 |
Cytokinetically based induction chemotherapy and splenectomy for childhood acute nonlymphocytic leukemia.
Topics: Acute Disease; Adolescent; Asparaginase; Brain Neoplasms; Child; Cyclophosphamide; Cytarabine; Doxorubicin; Humans; Injections, Spinal; Leukemia; Mercaptopurine; Methotrexate; Prednisone; Splenectomy; Vincristine | 1982 |
The efficiency of strict reverse isolation and antimicrobial decontamination in remission induction therapy of acute leukemia.
Topics: Acute Disease; Adult; Cytarabine; Daunorubicin; Decontamination; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Patient Isolation; Retrospective Studies | 1980 |
[Treatment of acute myeloblastic leukemia by the combination of daunorubicin (or rubidazone) and cytosine arabinoside (apropos of 76 cases)].
Topics: Acute Disease; Adult; Antineoplastic Agents; Cytarabine; Daunorubicin; Drug Therapy, Combination; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Middle Aged | 1980 |
Cytosine arabinoside influx and nucleoside transport sites in acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Binding Sites; Bone Marrow Cells; Carrier Proteins; Cell Transformation, Neoplastic; Child; Child, Preschool; Cytarabine; Humans; Infant; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Middle Aged; Nucleosides; Thioinosine; Time Factors | 1982 |
Prevention of blastic crisis in Ph1-positive chronic myeloid leukemia.
Topics: Acute Disease; Adult; Bone Marrow; Cytarabine; Doxorubicin; Drug Administration Schedule; Follow-Up Studies; Humans; Karyotyping; Leukemia, Myeloid; Leukocyte Count; Middle Aged; Platelet Count; Thioguanine; Vincristine | 1982 |
Acute pancreatitis in association with cytosine arabinoside therapy.
Topics: Acute Disease; Adolescent; Anorexia; Asparaginase; Cytarabine; Humans; Leukemia, Lymphoid; Male; Pain; Pancreatitis; Time Factors; Ultrasonography; Vomiting | 1982 |
Anthracyclines in the treatment of acute nonlymphocytic leukemias.
Topics: Acute Disease; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Bone Marrow; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Heart Diseases; Humans; Leukemia; Middle Aged; Naphthacenes | 1981 |
[Adriamycin and Ara-C infusions in the treatment of refractory leukemia].
Topics: Acute Disease; Adolescent; Child; Child, Preschool; Cytarabine; Doxorubicin; Drug Administration Schedule; Female; Humans; Infusions, Intra-Arterial; Leukemia; Leukemia, Lymphoid; Male | 1982 |
The University of Cape Town leukaemia centre: the first 5 years.
Topics: Academic Medical Centers; Acute Disease; Bone Marrow Transplantation; Cytarabine; Doxorubicin; Drug Therapy, Combination; Humans; Leukapheresis; Leukemia; Podophyllotoxin; South Africa; Transplantation, Homologous | 1980 |
Predictive value of the CFU-C assay in acute nonlymphocytic leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Bone Marrow Transplantation; Child; Child, Preschool; Colony-Forming Units Assay; Cytarabine; Doxorubicin; Drug Therapy, Combination; Humans; Leukemia; Middle Aged; Naphthacenes; Prognosis | 1982 |
Bone marrow cell count per cubic millimeter bone marrow: a new parameter for quantitating therapy-induced cytoreduction in acute leukemia.
Topics: Acute Disease; Bone Marrow; Cell Count; Cytarabine; Daunorubicin; Humans; Leukemia; Thioguanine; Thymidine | 1982 |
Acute leukemia in idiopathic sideroblastic anemia: response to combination chemotherapy.
Topics: Acute Disease; Aged; Anemia, Sideroblastic; Blood Transfusion; Cytarabine; Drug Therapy, Combination; Humans; Leukemia; Male; Middle Aged; Prednisone; Time Factors; Vincristine | 1982 |
Herpes zoster: a ten-year experience with cytosine arabinoside treatment.
Topics: Acute Disease; Adult; Aged; Cytarabine; Drug Evaluation; Female; Herpes Zoster; Humans; Male; Middle Aged | 1982 |
Chemotherapy sensitivity assessment of leukemic colony-forming cells with in vitro simultaneous exposure to multiple drugs: clinical correlations in acute nonlymphocytic leukemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clone Cells; Cytarabine; Daunorubicin; Doxorubicin; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Middle Aged; Prednisone; Vincristine | 1982 |
Treatment of refractory acute nonlymphocytic leukemia with a combination of pyrazofurin and cytarabine.
Topics: Acute Disease; Amides; Antibiotics, Antineoplastic; Cytarabine; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Humans; Leukemia; Pyrazoles; Ribonucleosides; Ribose | 1982 |
A prognostic factor analysis for use in development of predictive models for response in adult acute leukemia.
Topics: Acute Disease; Adult; Aged; Antibiotics, Antineoplastic; Bone Marrow; Cytarabine; Daunorubicin; Doxorubicin; Female; Humans; Leukemia; Male; Middle Aged; Prednisone; Prognosis; Vincristine | 1982 |
Prediction of remission in adult acute leukemia: development and testing of predictive models.
Topics: Acute Disease; Adult; Aged; Antibiotics, Antineoplastic; Cytarabine; Daunorubicin; Doxorubicin; Humans; Leukemia; Middle Aged; Models, Biological; Prednisone; Prognosis; Regression Analysis; Vincristine | 1982 |
Efficacy of granulocyte transfusions collected from nonstimulated donors.
Topics: Acute Disease; Aged; Agranulocytosis; Blood Donors; Blood Transfusion; Centrifugation; Cytarabine; Doxorubicin; Fever; Humans; Leukapheresis; Leukemia; Leukocyte Transfusion; Middle Aged; Premedication | 1982 |
Acute nonlymphoblastic leukemia: prognostic factors in adults with long-term follow-up.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bacterial Vaccines; Carmustine; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydroxyurea; Leukemia; Male; Methotrexate; Middle Aged; Platelet Count; Prognosis; Pseudomonas; Statistics as Topic; Thioguanine; Vincristine | 1982 |
Results of aggressive chemotherapy for acute nonlymphoblastic leukemia in adults.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents; Cytarabine; Daunorubicin; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Humans; Leukemia; Male; Middle Aged; Prednisone; Thioguanine; Time Factors; Vincristine | 1982 |
Sequential vincristine, arabinosylcytosine and adriamycin in acute leukemia: cytologic and cytokinetic studies.
Topics: Acute Disease; Cytarabine; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Humans; Interphase; Leukemia; Vincristine | 1982 |
Recruitment of quiescent tumor by humoral stimulatory activity: requirements for successful chemotherapy.
Topics: Acute Disease; Animals; Cell Division; Cell Survival; Cells, Cultured; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Leukemia; Leukemia, Experimental; Rats | 1982 |
Adriamycin combined with 10-day Ara-C, vincristine, and prednisone (10-day ADOAP) in the treatment of adult acute leukemia patients under fifty years of age. A Southwest Oncology Group Study.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Agents; Bone Marrow; Cytarabine; Doxorubicin; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Middle Aged; Prednisone; United States; Vincristine | 1982 |
Rubidazone in combination with Ara-C, vincristine and prednisone (ROAP) in the treatment of adult acute leukemia. A Southwest Oncology Group Study.
Topics: Acute Disease; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Bone Marrow; Cytarabine; Daunorubicin; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Middle Aged; Prednisone; United States; Vincristine | 1982 |
[DCTP (I) combination chemotherapy of adult acute non-lymphocytic leukemia].
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Middle Aged; Prednisolone; Thioguanine | 1982 |
The management of acute non-lymphocytic leukaemia in adults. Evaluation of the results in a non-selected group of 114 patients.
Topics: Acute Disease; Aged; Cytarabine; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Middle Aged; Retrospective Studies; Vincristine | 1982 |
[An in vitro chemotherapy sensitivity test on leukemic colony-forming cells (L-CFU) and its clinical evaluation].
Topics: Acute Disease; Antineoplastic Agents; Colony-Forming Units Assay; Cytarabine; Daunorubicin; Drug Evaluation, Preclinical; Drug Resistance; Hematopoietic Stem Cells; Humans; In Vitro Techniques; Leukemia | 1982 |
Maintenance management of acute nonlymphocytic leukemia.
Topics: Acute Disease; Adult; Aged; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Middle Aged; Statistics as Topic; Thioguanine; Time Factors | 1981 |
Induction therapy and intensive consolidation with daunorubicin, cytosine arabinoside, and 6-thioguanine in adult acute nonlymphoblastic leukemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Agents; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Middle Aged; Thioguanine | 1981 |
Growth and differentiation patterns of human acute non lymphoid leukemia in diffusion chambers before and after treatment.
Topics: Acute Disease; Adolescent; Adult; Aged; Animals; Cell Differentiation; Cells, Cultured; Child; Culture Techniques; Cytarabine; Daunorubicin; Female; Humans; Leukemia; Male; Methylprednisolone; Mice; Middle Aged; Thioguanine | 1981 |
Intensified remission induction therapy for acute nonlymphocytic leukemia (ANLL). Treatment report on 60 patients.
Topics: Acute Disease; Adolescent; Adult; Aged; Cytarabine; Daunorubicin; Humans; Leukemia; Middle Aged; Thioguanine; Thrombocytopenia | 1981 |
[Acute meningoencephalitis in children caused by herpes simplex virus type I].
Topics: Acute Disease; Antibodies, Viral; Child; Child, Preschool; Complement Fixation Tests; Cytarabine; Electroencephalography; Fever; Hemagglutination Tests; Herpes Simplex; Humans; Infant; Infant, Newborn; Meningoencephalitis; Prednisolone | 1981 |
Comparative chemotherapeutic investigations on transplanted and autochthonous acute rat leukemias.
Topics: Acute Disease; Animals; Antineoplastic Agents; Cytarabine; Doxorubicin; Drug Therapy, Combination; Leukemia, Experimental; Male; Neoplasm Transplantation; Prognosis; Rats; Vincristine | 1981 |
Management of patients with acute non-lymphocytic leukemia who fail first cycle of induction therapy.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Agents; Bone Marrow; Cell Count; Cytarabine; Doxorubicin; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Middle Aged; Prednisone; Prognosis; Thioguanine; Time Factors; Vincristine | 1981 |
[Treatment of acute leukemia with newly synthesized N4-behenoyl-l-beta-D-arabinofuranosylcytosine (BH-AC) (author's transl)].
Topics: Acute Disease; Adolescent; Adult; Aged; Cytarabine; Drug Evaluation; Female; Humans; Leukemia; Male; Middle Aged | 1981 |
Clinical implications of cytokinetic and biochemical features of acute leukemia cells.
Topics: Acute Disease; Cell Transformation, Neoplastic; Cytarabine; Daunorubicin; Humans; Leukemia; Prednisolone; Thioinosine | 1980 |
Phase III study of N4-behenoyl-l-beta-D-arabinofuranosylcytosine in adult acute leukemia-BH-AC-DMP therapy.
Topics: Acute Disease; Adolescent; Adult; Cytarabine; Daunorubicin; Female; Humans; Leukemia; Male; Middle Aged; Prednisolone; Thioinosine | 1980 |
Combination chemotherapy with daunorubicin, cytosine arabinoside and prednisolone (DAP) in acute nonlymphocytic leukemia.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Child; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Middle Aged; Prednisolone | 1981 |
[DCTP and DCMP two step therapy in acute non-lymphocytic leukemia (author's transl)].
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Agents; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia; Middle Aged; Prednisolone; Thioguanine; Thioinosine | 1980 |
Intensive five-drug combination chemotherapy for adult acute non-lymphocytic leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Agents; Arrhythmias, Cardiac; Cytarabine; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Heart Failure; Humans; Leukemia; Male; Middle Aged; Prednisone; Prognosis; Remission, Spontaneous; Thioguanine; Vincristine | 1980 |
Male fertility during chemotherapy for acute leukemia.
Topics: Acute Disease; Adult; Cytarabine; Daunorubicin; Female; Fertility; Humans; Leukemia; Male; Pregnancy; Thioguanine | 1980 |
A simple rapid autoradiography for 3H-thymidine labeling index and its application to therapy of adult acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Autoradiography; Cell Cycle; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged; Thymidine; Tritium | 1980 |
High-dose cytarabine, idarubicin, and granulocyte colony-stimulating factor remission induction therapy for previously untreated de novo and secondary adult acute myeloid leukemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Karyotyping; Leukemia, Myeloid; Male; Middle Aged; Remission Induction | 1993 |
[Successful collection of peripheral blood stem cells mobilized by a combination of G-CSF with high-dose Ara-C or high-dose etoposide].
Topics: Acute Disease; Adolescent; Adult; Blood Component Removal; Cytarabine; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Lymphoma, Non-Hodgkin; Male; Middle Aged | 1993 |
Acute leukemia complicating bone marrow hypoplasia in an adult with Shwachman's syndrome.
Topics: Acute Disease; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Male; Neutropenia; Pancreatic Diseases; Syndrome; Vidarabine | 1993 |
Upregulation of cell surface expression of T-lymphoid antigens and adhesion molecules on acute myeloid leukaemia cells after in vivo administration of granulocyte colony-stimulating factor.
Topics: Aclarubicin; Acute Disease; Aged; Antigens, CD; Antigens, Surface; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Cells; Cell Adhesion Molecules; Cell Separation; Cytarabine; Female; Flow Cytometry; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid; T-Lymphocytes; Up-Regulation | 1994 |
Secondary tumours following etoposide containing therapy for germ cell cancer.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cohort Studies; Cyclophosphamide; Cytarabine; Dactinomycin; Dose-Response Relationship, Drug; Etoposide; Germinoma; Humans; Leukemia, Myeloid; Male; Methotrexate; Middle Aged; Neoplasms, Second Primary; Testicular Neoplasms; Vincristine | 1995 |
Predictive value for treatment outcome in acute myeloid leukemia of cellular daunorubicin accumulation and P-glycoprotein expression simultaneously determined by flow cytometry.
Topics: Acute Disease; Adolescent; Adult; Aged; Antigens, CD; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blast Crisis; Blood Cell Count; Bone Marrow; Chromosome Deletion; Chromosomes, Human, Pair 7; Cytarabine; Daunorubicin; Drug Resistance, Multiple; Female; Flow Cytometry; Gene Expression; Humans; Idarubicin; Karyotyping; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Monosomy; Myelodysplastic Syndromes; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplastic Stem Cells; Prognosis; Prospective Studies; Quinine; Remission Induction; Risk; Salvage Therapy; Treatment Outcome | 1995 |
CD7 expression does not predict for poor outcome in acute myeloblastic leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antigens, CD; Antigens, CD7; Antigens, Differentiation, T-Lymphocyte; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Neoplastic Stem Cells; Prognosis; Retrospective Studies; Survival Analysis; T-Lymphocyte Subsets | 1995 |
Multidrug resistant cells with high proliferative capacity determine response to therapy in acute myeloid leukemia.
Topics: Acute Disease; Age Factors; Analysis of Variance; Antigens, CD; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biomarkers, Tumor; Bone Marrow; Cell Division; Cells, Cultured; Cytarabine; Daunorubicin; Drug Resistance, Multiple; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Monocytes; Predictive Value of Tests; Remission Induction; Survival Rate | 1995 |
The effect of haemopoietic growth factors on the cell cycle of AML progenitors and their sensitivity to cytosine arabinoside in vitro.
Topics: Acute Disease; Bone Marrow; Cell Cycle; Cells, Cultured; Cytarabine; Flow Cytometry; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cells; Humans; Interleukin-3; Leukemia, Myeloid | 1995 |
Direct evidence for the participation of bcl-2 in the regulation by retinoic acid of the Ara-C sensitivity of leukemic stem cells.
Topics: Acute Disease; Antineoplastic Agents; Cell Survival; Cytarabine; Drug Resistance, Neoplasm; Humans; Hydrogen Peroxide; Leukemia, Myeloid; Oncogenes; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Transfection; Tretinoin; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1995 |
Rapid engraftment after autologous transplantation utilizing marrow and recombinant granulocyte colony-stimulating factor-mobilized peripheral blood stem cells in patients with acute myelogenous leukemia.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Purging; Bone Marrow Transplantation; Child; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Etoposide; Female; Graft Survival; Granulocyte Colony-Stimulating Factor; Granulocytes; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Leukocyte Count; Life Tables; Male; Middle Aged; Recombinant Proteins; Remission Induction; Retrospective Studies; Transplantation, Autologous; Treatment Outcome | 1995 |
Epiglottitis following preparation for allogeneic bone marrow transplantation.
Topics: Acute Disease; Bone Marrow Transplantation; Child; Combined Modality Therapy; Cytarabine; Epiglottis; Epiglottitis; Humans; Male; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Radiation Injuries; Whole-Body Irradiation | 1995 |
Cytogenetic and clinical correlates in AML patients with abnormalities of chromosome 16.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Chromosome Inversion; Chromosome Mapping; Chromosomes, Human, Pair 16; Cytarabine; Cytogenetics; Humans; Karyotyping; Leukemia, Myeloid; Myelodysplastic Syndromes; Predictive Value of Tests; Prognosis; Sequence Deletion; Survival Rate; Treatment Outcome | 1995 |
Hypoplastic acute myeloid leukaemia with 7 years of complete remission by low-dose cytosine arabinoside therapy alone.
Topics: Acute Disease; Aged; Cytarabine; Female; Humans; Leukemia, Myeloid; Remission Induction | 1995 |
Role of deoxycytidine kinase in an in vitro model for AraC- and DAC-resistance: substrate-enzyme interactions with deoxycytidine, 1-beta-D-arabinofuranosylcytosine and 5-aza-2'-deoxycytidine.
Topics: Acute Disease; Animals; Antineoplastic Agents; Azacitidine; Binding, Competitive; Cytarabine; Decitabine; Deoxycytidine; Deoxycytidine Kinase; Drug Resistance; In Vitro Techniques; Kinetics; Leukemia, Myeloid; Rats; Rats, Inbred BN; Tumor Cells, Cultured | 1993 |
Influence of schedule on regulated sensitivity of AML blasts to cytosine arabinoside.
Topics: Acute Disease; Aged; Cell Survival; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; In Vitro Techniques; Leukemia, Myeloid; Male; Methylcellulose; Middle Aged; Tretinoin; Tumor Cells, Cultured | 1993 |
Synergistic and antagonistic effects of myeloid growth factors on in vitro cellular killing by cytotoxic drugs.
Topics: Aclarubicin; Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Death; Cell Survival; Coloring Agents; Cytarabine; Daunorubicin; Drug Antagonism; Drug Screening Assays, Antitumor; Drug Synergism; Female; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-3; Leukemia, Myeloid; Male; Middle Aged; Prospective Studies; Remission Induction | 1993 |
[Acute right ventricular insufficiency reversible following anthracycline treatment].
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Doxorubicin; Female; Humans; Leukemia, Myeloid, Acute; Time Factors; Ventricular Dysfunction, Right | 1995 |
[Results of induction therapy in newly diagnosed acute myeloid leukemias in study 911 at the Institute of Hematology and Blood Transfusion].
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Remission Induction | 1995 |
Transverse nail ridgings (Beau's lines) induced by chemotherapy--a dose-dependent phenomenon.
Topics: Acute Disease; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid; Nail Diseases; Nails | 1994 |
Timed sequential chemotherapy for previously treated patients with acute myeloid leukemia: long-term follow-up of the etoposide, mitoxantrone, and cytarabine-86 trial.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Drug Administration Schedule; Etoposide; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Prognosis; Recurrence; Remission Induction; Treatment Outcome | 1995 |
[Hemostasis in patients with acute leukemia treated with high doses of cytosine-arabinoside: the effect of chemotherapy and infectious complications on hemostasis].
Topics: Acute Disease; Adolescent; Adult; Cytarabine; Female; Hemostasis; Humans; Leukemia, Myeloid; Male; Middle Aged; Opportunistic Infections; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1994 |
Post-remission chemotherapy for acute myeloid leukemia.
Topics: Acute Disease; Adult; Cytarabine; Humans; Leukemia, Myeloid; Middle Aged; Remission Induction | 1995 |
Salivary glands enlargement in association with cytosine arabinoside application in patients with acute myeloid leukaemia.
Topics: Acute Disease; Adolescent; Adult; Cytarabine; Humans; Leukemia, Myeloid; Male; Sialadenitis | 1994 |
Benefit of high-dose cytarabine-based consolidation chemotherapy for adults with acute myelogenous leukemia.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; California; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Leukemia, Myeloid; Life Tables; Male; Middle Aged; Mitoxantrone; Preleukemia; Remission Induction; Survival Analysis; Thioguanine; Treatment Outcome | 1994 |
Acute leukemia coexpressing myeloid, B- and T-lineage associated markers: multiparameter analysis of criteria defining lineage commitment and maturational stage in a case of undifferentiated leukemia.
Topics: Acute Disease; Antigens, CD; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Marrow; Cytarabine; Daunorubicin; Fatal Outcome; Female; Hematopoietic Cell Growth Factors; Humans; Immunophenotyping; Leukemia; Middle Aged; Mitoxantrone; Neoplastic Stem Cells; Remission Induction; Thioguanine; Tumor Stem Cell Assay | 1995 |
Low frequency of activity of P-glycoprotein (P-170) in acute lymphoblastic leukemia compared to acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Marrow; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Resistance, Multiple; Female; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Neoplasm Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Remission Induction; Rhodamine 123; Rhodamines; Survival Analysis | 1995 |
Combined antileukemic activity of pIXY 321 and Ara-C against human acute myeloid leukemia cells.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Northern; Blotting, Western; Cytarabine; DNA, Neoplasm; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-3; Leukemia, Myeloid; Nucleosomes; Recombinant Fusion Proteins; Tumor Cells, Cultured | 1994 |
[Mitoxantrone-aracytine with or without quinine in the treatment of refractory or relapsed acute leukemia].
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged; Mitoxantrone; Quinine; Recurrence | 1994 |
Detection of cytarabine resistance in patients with acute myelogenous leukemia using flow cytometry.
Topics: Acute Disease; Adolescent; Adult; Aged; Cell Division; Clone Cells; Cytarabine; Drug Resistance; Female; Flow Cytometry; Humans; Leukemia, Myeloid; Male; Middle Aged; Prognosis | 1994 |
Capacity of individual chronic lymphatic leukemia lymphocytes and leukemic blast cells for repair of O6-ethylguanine in DNA: relation to chemosensitivity in vitro and treatment outcome.
Topics: Acute Disease; Carmustine; Cyclophosphamide; Cytarabine; DNA Repair; Doxorubicin; Drug Resistance; Ethylnitrosourea; Glutathione; Guanine; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid; Lymphocytes; Treatment Outcome | 1994 |
Daunorubicin (DNR) accumulation in fresh leukemic cells: correlation with clinical and biological features.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Biological Transport; Bone Marrow; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Female; Flow Cytometry; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Neoplastic Stem Cells; Stimulation, Chemical; Treatment Failure; Verapamil | 1994 |
Intensified therapy for acute myeloid leukemia.
Topics: Acute Disease; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid; Remission Induction | 1994 |
Pulmonary insufficiency complicating therapy with high dose cytosine arabinoside in five pediatric patients with relapsed acute myelogenous leukemia.
Topics: Acute Disease; Cause of Death; Child; Child, Preschool; Cytarabine; Female; Humans; Leukemia, Myeloid; Male; Pulmonary Edema; Respiratory Insufficiency; Salvage Therapy | 1994 |
[Neutropenic typhlitis: a frequently missed complication of aplasia-inducing tumor therapy with a possible association to the combination of etoposide with high-dose cytosine-arabinoside].
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Synergism; Enterocolitis, Pseudomembranous; Etoposide; Female; Humans; Leukemia; Male; Neutropenia; Retrospective Studies | 1994 |
Post-remission cytopenias following intense induction chemotherapy for acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Anemia; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Neutropenia; Recurrence; Remission Induction; Thrombocytopenia; Time Factors; Treatment Outcome | 1994 |
Successful treatment of low dose cytosine arabinoside for acute myelofibrosis with immature myeloblast (AML-MO)
Topics: Acute Disease; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Middle Aged; Primary Myelofibrosis | 1994 |
Low-dose ara-C in myelodysplastic syndromes (MDS) and acute leukemia following MDS: proposal for a predictive model.
Topics: Acute Disease; Aged; Aged, 80 and over; Cytarabine; Humans; Leukemia, Myeloid, Acute; Middle Aged; Models, Biological; Myelodysplastic Syndromes; Survival Rate | 1994 |
Effects of macrophage colony-stimulating factor (M-CSF) on the mobilization of peripheral blood stem cells.
Topics: Acute Disease; Adolescent; Adult; Blood Cells; Cell Movement; Cells, Cultured; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Female; Hematopoietic Stem Cells; Humans; Leukapheresis; Leukemia, Myeloid; Macrophage Colony-Stimulating Factor; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1994 |
[The use of diflucan in myelotoxic agranulocytosis].
Topics: Acute Disease; Adult; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Candidiasis; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Evaluation; Female; Fluconazole; Humans; Leukemia; Prednisolone; Vincristine | 1993 |
[The current chemotherapy of acute myeloid leukemias in adults].
Topics: Aclarubicin; Acute Disease; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Humans; Idarubicin; Leukemia, Myeloid; Mitoxantrone; Prognosis; Remission Induction; Time Factors | 1993 |
Idarubicin in the therapy of acute myeloid leukemia: final analysis in 57 previously untreated patients.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Chemotherapy, Adjuvant; Cytarabine; Female; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Remission Induction; Survival Analysis | 1993 |
Resistance to cytosine arabinoside in acute leukemia: the significance of mutations in CTP synthetase.
Topics: Acute Disease; Adult; Carbon-Nitrogen Ligases; Cytarabine; DNA Mutational Analysis; Drug Resistance; Humans; Leukemia; Ligases; Mutation; Tumor Cells, Cultured | 1994 |
Acute myeloid leukemia presenting as granulocytic sarcoma of the lung.
Topics: Acute Disease; Adult; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Diagnosis, Differential; Etoposide; Humans; Leukemia, Myeloid; Lung Neoplasms; Male | 1993 |
Treatment of childhood acute myeloid leukaemia using the BFM-83 protocol.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myeloid; Life Tables; Male; Survival Analysis; Treatment Outcome | 1993 |
Clinical and prognostic significance of in vivo differentiation in acute myeloid leukemia.
Topics: Acute Disease; Antibodies, Monoclonal; Biopsy, Needle; Bone Marrow; Bromodeoxyuridine; Cell Cycle; Cell Differentiation; Cell Division; Cytarabine; Daunorubicin; Drug Therapy, Combination; Granulocytes; Humans; Leukemia, Myeloid; Prognosis; Remission Induction; Risk Factors | 1993 |
Therapy of refractory/relapsed acute myeloid leukemia and blast crisis of chronic myeloid leukemia with the combination of cytosine arabinoside, tetrahydrouridine, and carboplatin.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Carboplatin; Cytarabine; Drug Resistance; Female; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Male; Middle Aged; Recurrence; Tetrahydrouridine; Treatment Outcome | 1993 |
[Successful treatment with combination chemotherapy of BHAC-AMP in a case of acute myelofibrosis developed from myelodysplastic syndrome with multiple chromosomal aberrations].
Topics: Aclarubicin; Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Chromosome Aberrations; Cytarabine; Humans; Male; Mercaptopurine; Middle Aged; Myelodysplastic Syndromes; Prednisolone; Primary Myelofibrosis | 1993 |
Role of total body irradiation as based on the comparison of preparation regimens for allogeneic bone marrow transplantation for acute leukemia in first complete remission.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Etoposide; Female; Humans; Infant; Japan; Leukemia; Male; Methotrexate; Nimustine; Proportional Hazards Models; Radiotherapy Dosage; Remission Induction; Transplantation, Homologous; Whole-Body Irradiation | 1993 |
Incidence of chromosome abnormalities and clinical significance of karyotype in de novo acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Daunorubicin; Female; Humans; Incidence; Karyotyping; Leukemia, Myeloid; Male; Middle Aged; Prognosis; Translocation, Genetic | 1993 |
Low-dose cytosine arabinoside in patients with acute myeloid leukemia not eligible for standard chemotherapy.
Topics: Acute Disease; Adult; Aged; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Retrospective Studies; Survival Analysis | 1995 |
Selective discharge of patients with acute myeloid leukemia during chemotherapy-induced neutropenia.
Topics: Acute Disease; Adult; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Bacterial Infections; Catheterization, Central Venous; Cross Infection; Cytarabine; Daunorubicin; Disease Susceptibility; Etoposide; Female; Fever; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Neutropenia; Patient Discharge; Safety; Treatment Outcome | 1996 |
Central nervous system granulocytic sarcoma in a patient with essential thrombocythemia.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Blast Crisis; Bone Marrow; Busulfan; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease Progression; Epidural Space; Fatal Outcome; Frontal Bone; Humans; Leukemia, Myeloid; Leukemic Infiltration; Male; Methylprednisolone; Spinal Canal; Thrombocythemia, Essential | 1996 |
Pneumocystis carinii pneumonia in adults with acute leukaemia: is there a need for primary chemoprophylaxis?
Topics: Aclarubicin; Acute Disease; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cohort Studies; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Etoposide; Female; Finland; Humans; Immunocompromised Host; Incidence; Leukemia; Male; Mercaptopurine; Methotrexate; Middle Aged; Mitoxantrone; Pneumonia, Pneumocystis; Prednisone; Premedication; Retrospective Studies; Thioguanine; Trimethoprim, Sulfamethoxazole Drug Combination; Vincristine | 1996 |
Enhanced metabolism of 1-beta-D-arabinofuranosylcytosine in Down syndrome cells: a contributing factor to the superior event free survival of Down syndrome children with acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Cell Line, Transformed; Cells, Cultured; Child; Child, Preschool; Chromosomes, Human, Pair 21; Cystathionine beta-Synthase; Cytarabine; Deoxycytosine Nucleotides; Disease-Free Survival; Down Syndrome; Female; Herpesvirus 4, Human; Homocysteine; Humans; Infant; Infant, Newborn; Leukemia, Megakaryoblastic, Acute; Leukemia, Myeloid; Male; Methotrexate; Myelodysplastic Syndromes; Neoplastic Stem Cells; Remission, Spontaneous; Survival Rate | 1996 |
Acute pancreatitis associated with continuous infusion cytarabine therapy: a case report.
Topics: Acute Disease; Adult; Cytarabine; Humans; Infusions, Intravenous; Leukemia, Monocytic, Acute; Male; Pancreatitis; Tomography, X-Ray Computed | 1996 |
Renal venous thrombosis complicating acute myeloid leukemia with hyperleukocytosis.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Atrophy; Cytarabine; Daunorubicin; Humans; Infant; Kidney; Leukapheresis; Leukemia, Myeloid; Leukocyte Count; Leukocytosis; Male; Renal Veins; Thioguanine; Thrombosis; Tomography, X-Ray Computed; Ultrasonography, Doppler | 1996 |
In vitro resistance to cytosine arabinoside, not to daunorubicin, is associated with the risk of relapse in de novo acute myeloid leukaemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Amsacrine; Antigens, CD34; Antineoplastic Agents; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Etoposide; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Recurrence; Risk Factors; Treatment Outcome | 1996 |
Expression of Fas antigen in acute myeloid leukaemia is associated with therapeutic response to chemotherapy.
Topics: Acute Disease; Adult; Antineoplastic Agents; Bone Marrow; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; fas Receptor; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Thioguanine; Treatment Outcome | 1996 |
Central nervous system relapse after bone marrow transplantation for acute leukemia in first remission.
Topics: Actuarial Analysis; Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cerebrospinal Fluid; Child, Preschool; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Disease-Free Survival; Female; Humans; Hydrocortisone; Injections, Spinal; Leukemia; Leukemic Infiltration; Male; Meninges; Methotrexate; Prospective Studies; Recurrence; Remission Induction; Risk; Transplantation, Homologous; Treatment Outcome; Whole-Body Irradiation | 1996 |
Detection of minimal residual disease by polymerase chain reaction in B cell malignancies.
Topics: Acute Disease; Base Sequence; Burkitt Lymphoma; Cytarabine; Dose-Response Relationship, Immunologic; Gene Rearrangement; Hematopoietic Stem Cell Transplantation; Humans; Leukapheresis; Leukemia, Myeloid; Lymphoma, Non-Hodgkin; Molecular Sequence Data; Multiple Myeloma; Neoplasm, Residual; Polymerase Chain Reaction; Transcription, Genetic | 1995 |
[CD7, HLA-DR, CD38 positive acute undifferentiated leukemia with subcutaneous tumor and thymoma].
Topics: Acute Disease; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Antigens, CD; Antigens, CD7; Antigens, Differentiation; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Etoposide; Gene Rearrangement; HLA-DR Antigens; Humans; Immunoglobulin Heavy Chains; Immunophenotyping; Leukemia; Membrane Glycoproteins; Mitoxantrone; N-Glycosyl Hydrolases; Prednisolone; Receptors, Antigen, T-Cell, gamma-delta; Remission Induction; Skin Neoplasms; Thymoma; Thymus Neoplasms | 1996 |
Autologous transplantation with peripheral blood stem cells collected after granulocyte colony-stimulating factor in patients with acute myelogenous leukemia.
Topics: Acute Disease; Adolescent; Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Blood Cells; Bone Marrow; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Disease-Free Survival; Etoposide; Graft Survival; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Life Tables; Middle Aged; Mitoxantrone; Recombinant Proteins; Remission Induction; Retrospective Studies; Salvage Therapy; Survival Analysis; Thioguanine; Transplantation Conditioning; Transplantation, Autologous; Treatment Outcome; Whole-Body Irradiation | 1996 |
Optimizing therapy for acute myeloid leukemia based on differences in intracellular metabolism of cytosine arabinoside between leukemic blasts and normal mononuclear blood cells.
Topics: Acute Disease; Antimetabolites, Antineoplastic; Arabinofuranosylcytosine Triphosphate; Arabinofuranosyluracil; Cytarabine; Female; Humans; Leukemia, Myeloid; Leukocytes, Mononuclear; Male | 1996 |
Cerebellar toxicity with medium-dose cytarabine in a young patient with renal insufficiency.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Diseases; Cytarabine; Daunorubicin; Female; Humans; Kidney; Kidney Failure, Chronic; Leukemia, Myeloid; Lupus Nephritis; Mitoxantrone | 1996 |
Acute polyneuropathy after high dose cytosine arabinoside in patients with leukemia.
Topics: Acute Disease; Adult; Antimetabolites, Antineoplastic; Cerebellar Diseases; Cytarabine; Demyelinating Diseases; Female; Humans; Leukemia; Male; Middle Aged; Peripheral Nervous System Diseases; Retrospective Studies | 1996 |
Autologous peripheral blood stem cell transplantation in a patient with previous invasive middle ear mucormycosis.
Topics: Acute Disease; Amphotericin B; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Facial Paralysis; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Leukemia, Myeloid; Male; Mastoid; Middle Aged; Mitoxantrone; Mucormycosis; Myringoplasty; Neutropenia; Otitis Media, Suppurative; Remission Induction; Transplantation Conditioning; Transplantation, Autologous | 1996 |
Measurement of spontaneous and therapeutic agent-induced apoptosis with BCL-2 protein expression in acute myeloid leukemia.
Topics: Acute Disease; Antineoplastic Agents; Apoptosis; Bone Marrow; Cell Separation; Cytarabine; Daunorubicin; Disease Progression; Flow Cytometry; Gene Expression Regulation, Leukemic; Genes, p53; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid; Neoplasm Proteins; Neoplastic Stem Cells; Proto-Oncogene Proteins c-bcl-2; Reproducibility of Results; Sensitivity and Specificity; Tumor Cells, Cultured | 1997 |
High antileukemic activity of sequential high dose cytosine arabinoside and mitoxantrone in patients with refractory acute leukemias. Results of a clinical phase II study.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction | 1997 |
Protective effects of cardioxane against anthracycline-induced cardiotoxicity in relapsed acute myeloid leukemias.
Topics: Acute Disease; Antibiotics, Antineoplastic; Antineoplastic Agents; Cardiovascular Agents; Cytarabine; Daunorubicin; Female; Heart; Humans; Leukemia, Myeloid; Male; Middle Aged; Razoxane; Recurrence | 1996 |
FLAG (fludarabine, cytosine arabinoside, G-CSF) for refractory and relapsed acute myeloid leukemia.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Central Nervous System Diseases; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Male; Middle Aged; Nausea; Neutropenia; Treatment Outcome; Vidarabine; Vomiting | 1996 |
Detection of a dormant 20q- leukemia clone in bone marrow cultures with hematopoietic growth factors: implications for secondary leukemia post-transplant.
Topics: Acute Disease; Adult; Anemia, Refractory, with Excess of Blasts; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow; Bone Marrow Transplantation; Chromosome Deletion; Chromosomes, Human, Pair 20; Clone Cells; Combined Modality Therapy; Cytarabine; Dacarbazine; Doxorubicin; Female; Hematopoietic Cell Growth Factors; Hodgkin Disease; Humans; Mechlorethamine; Neoplasm, Residual; Neoplasms, Second Primary; Neoplastic Stem Cells; Prednisone; Procarbazine; Radiotherapy; Recurrence; Transplantation, Autologous; Vinblastine; Vincristine | 1997 |
CD8+ T cells activated during the course of murine acute myelogenous leukemia elicit therapeutic responses to late B7 vaccines after cytoreductive treatment.
Topics: Acute Disease; Animals; Antimetabolites, Antineoplastic; B7-1 Antigen; CD8-Positive T-Lymphocytes; Cells, Cultured; Combined Modality Therapy; Cytarabine; Evaluation Studies as Topic; Female; Immunization Schedule; Immunotherapy, Active; Immunotherapy, Adoptive; Leukemia, Myeloid; Leukemia, Radiation-Induced; Lymphocyte Activation; Lymphokines; Mice; Mice, Inbred Strains; Neoplasm Transplantation; T-Lymphocytes, Cytotoxic; Th1 Cells; Tumor Cells, Cultured; Vaccines | 1997 |
Single weekly cytosine arabinoside and oral 6-thioguanine in patients with myelodysplastic syndrome and acute myeloid leukemia.
Topics: Acute Disease; Administration, Oral; Adult; Aged; Aged, 80 and over; Cytarabine; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Injections, Subcutaneous; Leukemia, Myeloid; Male; Middle Aged; Myelodysplastic Syndromes; Palliative Care; Platelet Transfusion; Thioguanine; Thrombocytopenia | 1997 |
Study of the apoptosis induced in vitro by antitumoral drugs on leukaemic cells.
Topics: Acute Disease; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Cell Cycle; Cytarabine; Daunorubicin; Drug Screening Assays, Antitumor; Flow Cytometry; Humans; Idarubicin; Kinetics; Leukemia; Mitoxantrone | 1997 |
Acute and painful erythema of the hands and feet. Acral erythema induced by chemotherapy.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Eruptions; Erythema; Female; Foot Dermatoses; Hand Dermatoses; Humans; Middle Aged; Pain | 1997 |
Sensitivity of acute leukemia cells to cytarabine is a correlate of cellular es nucleoside transporter site content measured by flow cytometry with SAENTA-fluorescein.
Topics: Acute Disease; Adenosine; Affinity Labels; Antimetabolites, Antineoplastic; Carrier Proteins; Cell Death; Cytarabine; Flow Cytometry; Fluorescein; Fluoresceins; Humans; Leukemia; Nucleosides; Thionucleosides; Tumor Cells, Cultured | 1997 |
Allogeneic bone marrow transplantation for children with acute leukemia: long-term follow-up of patients prepared with high-dose cytosine arabinoside and fractionated total body irradiation.
Topics: Acute Disease; Adolescent; Adult; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Follow-Up Studies; Graft Survival; Humans; Infant; Leukemia; Myelodysplastic Syndromes; Transplantation, Homologous; Treatment Outcome; Whole-Body Irradiation | 1997 |
Bayesian interim analysis of phase II cancer clinical trials.
Topics: Acute Disease; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bayes Theorem; Clinical Trials, Phase II as Topic; Cytarabine; Humans; Idarubicin; Leukemia, Myeloid; Models, Statistical; Research Design; Vidarabine | 1997 |
Activity of thymidine kinase and of polymerase alpha as well as activity and gene expression of deoxycytidine deaminase in leukemic blasts are correlated with clinical response in the setting of granulocyte-macrophage colony-stimulating factor-based primi
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Cytidine Deaminase; Daunorubicin; DNA Polymerase II; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Lymphocytes; Male; Middle Aged; Nucleoside Deaminases; Thioguanine; Thymidine Kinase | 1997 |
Myeloblasts from Down syndrome children with acute myeloid leukemia have increased in vitro sensitivity to cytosine arabinoside and daunorubicin.
Topics: Acute Disease; Bone Marrow; Cell Survival; Child; Cytarabine; Daunorubicin; Down Syndrome; Humans; Leukemia, Myeloid; Tumor Cells, Cultured | 1997 |
Successful collection of peripheral blood progenitor cells in patients with acute myeloid leukaemia following early consolidation therapy with granulocyte colony-stimulating factor-supported high-dose cytarabine and mitoxantrone.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Multivariate Analysis | 1997 |
Effect on cell kill of addition of multidrug resistance modifiers cyclosporin A and PSC 833 to cytotoxic agents in acute myeloid leukaemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Survival; Coloring Agents; Cyclosporine; Cyclosporins; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Drug Synergism; Etoposide; Female; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1997 |
Long-term survival of patients with acute myeloid leukemia: updated results from two trials evaluating postinduction chemotherapy.
Topics: Acute Disease; Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Remission Induction; Survival Analysis; Time Factors | 1997 |
Pharmacokinetics of high-dose cytarabine and its deamination product--a reappraisal.
Topics: Acute Disease; Adult; Aged; Antimetabolites, Antineoplastic; Arabinofuranosyluracil; Cytarabine; Deamination; Dose-Response Relationship, Drug; Female; Humans; Leukemia; Male; Middle Aged; Myelodysplastic Syndromes | 1997 |
The prognostic significance of chromosomal analysis and immunophenotyping in 117 patients with de novo acute myeloid leukemia.
Topics: Acute Disease; Adult; Aged; Antibiotics, Antineoplastic; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antimetabolites, Antineoplastic; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Immunophenotyping; Karyotyping; Leukemia, Myeloid; Male; Middle Aged; Multivariate Analysis; Prognosis; Remission Induction; Retrospective Studies; Sialic Acid Binding Ig-like Lectin 3 | 1997 |
Fludarabine, cytarabine, G-CSF and idarubicin (FLAG-IDA) for the treatment of poor-risk myelodysplastic syndromes and acute myeloid leukaemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Length of Stay; Leukemia, Myeloid; Leukocyte Count; Male; Middle Aged; Myelodysplastic Syndromes; Neutrophils; Platelet Count; Survival Rate; Treatment Outcome; Vidarabine | 1997 |
MDR1 gene expression and drug resistance of AML cells.
Topics: Aclarubicin; Acute Disease; Antineoplastic Agents; Cytarabine; Daunorubicin; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Gene Expression; Genes, MDR; Humans; Lethal Dose 50; Leukemia, Myeloid; Mitoxantrone; Tumor Cells, Cultured | 1998 |
Acute basal ganglia necrosis associated with cytarabine therapy.
Topics: Acute Disease; Antimetabolites, Antineoplastic; Basal Ganglia; Child, Preschool; Cytarabine; Humans; Male; Necrosis; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1998 |
Inv(16) acute myeloid leukemia cells show an increased sensitivity to cytosine arabinoside in vitro.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Apoptosis; Chromosome Aberrations; Chromosome Inversion; Chromosomes, Human, Pair 16; Cytarabine; DNA, Neoplasm; Drug Screening Assays, Antitumor; Female; Humans; Karyotyping; Leukemia, Myeloid; Male; Middle Aged; Tumor Cells, Cultured | 1998 |
High-dose therapy in acute leukemia.
Topics: Acute Disease; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Transplantation Conditioning; Transplantation, Autologous; Transplantation, Homologous | 1997 |
Fludarabine and cytosine-arabinoside for poor-risk acute myeloid leukemia.
Topics: Acute Disease; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Remission Induction; Risk Factors; Time Factors; Vidarabine | 1998 |
[Acute myeloid leukemia in those over 70 years of age. Experience using low-dose ara-C treatment].
Topics: Acute Disease; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Evaluation; Female; Humans; Leukemia, Myeloid; Life Tables; Male; Myelodysplastic Syndromes; Prednisone; Remission Induction; Retrospective Studies; Survival Analysis; Survival Rate; Thioguanine; Treatment Outcome; Vincristine; Waldenstrom Macroglobulinemia | 1998 |
Patients with isolated trisomy 8 in acute myeloid leukemia are not cured with cytarabine-based chemotherapy: results from Cancer and Leukemia Group B 8461.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antimetabolites, Antineoplastic; Chromosomes, Human, Pair 8; Cohort Studies; Cytarabine; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Prospective Studies; Survival Analysis; Treatment Outcome; Trisomy | 1998 |
Granulocyte-macrophage colony-stimulating factor in post-remission therapy of acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Remission Induction; Survival Rate | 1998 |
Cell cycle perturbations in acute myeloid leukemia samples following in vitro exposures to therapeutic agents.
Topics: Acute Disease; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Cell Cycle; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Flow Cytometry; Genes, p53; Humans; Immunophenotyping; Karyotyping; Leukemia, Myeloid; Mutation; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-bcl-2; Reproducibility of Results; Sensitivity and Specificity | 1998 |
Modulation of resistance to ara-C by bryostatin in fresh blast cells from patients with AML.
Topics: Acute Disease; Antineoplastic Agents; Arabinofuranosylcytosine Triphosphate; Bryostatins; Cell Death; Cytarabine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Lactones; Leukemia, Myeloid; Leukocytes, Mononuclear; Macrolides; Tetrazolium Salts; Thiazoles | 1998 |
Cellular immune responses in acute leukaemia patients with severe chemotherapy-induced leucopenia; characterization of the cytokine repertoire of clonogenic T cells.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Clone Cells; Cytarabine; Cytokines; Daunorubicin; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-10; Interleukin-2; Leukemia, Myeloid; Leukopenia; Lymphopenia; Male; Middle Aged; Phytohemagglutinins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stimulation, Chemical | 1998 |
Impact of exogenous growth factors on proliferation and chemosensitivity of minimal residual acute myeloid leukemia.
Topics: Acute Disease; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-3; Ki-67 Antigen; Leukemia, Myeloid; Middle Aged; Neoplasm, Residual; Remission Induction; Tumor Stem Cell Assay | 1998 |
Acute myeloid leukemia in the elderly: a critical review of therapeutic approaches and appraisal of results of therapy.
Topics: Acute Disease; Age Factors; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Multivariate Analysis; Remission Induction; Survival Analysis | 1998 |
A rare atypical myeloproliferative-disorder-like hemopathy with marked dysplasia, peripheral dominant myeloblast proliferation and extramedullary hematopoiesis was converted into typical acute myeloid leukemia with an interval of complete hematological re
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Daunorubicin; Disease Progression; Hematopoiesis, Extramedullary; Humans; Leukemia, Myeloid; Male; Mercaptopurine; Middle Aged; Myelodysplastic Syndromes; Myeloproliferative Disorders; Prednisolone; Preleukemia; Remission Induction | 1998 |
Proportion of blasts with a clear halo around nucleoli at the end of induction therapy of acute myeloid leukemia correlates with achievement of complete remission, remission duration and relapse.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells; Cell Nucleolus; Child; Child, Preschool; Cytarabine; Daunorubicin; Disease-Free Survival; Humans; Immunoenzyme Techniques; Ki-67 Antigen; Leukemia, Myeloid; Mercaptopurine; Middle Aged; Neoplasm Recurrence, Local; Prednisolone; Remission Induction; Retrospective Studies; Vincristine | 1998 |
Expression and function of the megakaryocyte growth and development factor receptor in acute myeloid leukemia blasts.
Topics: Acute Disease; Adult; Aged; Antimetabolites, Antineoplastic; Apoptosis; Cell Cycle; Cell Division; Cytarabine; Drug Interactions; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Middle Aged; Neoplasm Proteins; Proto-Oncogene Proteins; Receptors, Cytokine; Receptors, Thrombopoietin; RNA, Messenger; Stem Cell Factor; Thrombopoietin; Thymidine; Trans-Activators | 1998 |
Case 17: Essential thrombocythaemia with inversion 3 terminating in acute leukaemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Chromosome Inversion; Chromosomes, Human, Pair 3; Cytarabine; Etoposide; Fatal Outcome; Female; Humans; Karyotyping; Leukemia; Middle Aged; Mitoxantrone; Thrombocythemia, Essential | 1998 |
Disappearance of AML1-MTG8 transcript by reverse transcriptase polymerase chain reaction in a patient in remission of acute myeloid leukemia (M2) after low-dose cytosine arabinoside.
Topics: Acute Disease; Aged; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Core Binding Factor Alpha 2 Subunit; Cytarabine; Humans; Leukemia, Myeloid; Neoplasm, Residual; Oncogene Proteins, Fusion; Polymerase Chain Reaction; Recombinant Fusion Proteins; Remission Induction; RNA-Directed DNA Polymerase; RNA, Messenger; RUNX1 Translocation Partner 1 Protein; Transcription Factors; Translocation, Genetic | 1998 |
Desferioxamine increases iron depletion and apoptosis induced by ara-C of human myeloid leukaemic cells.
Topics: Acute Disease; Antidotes; Antimetabolites, Antineoplastic; Apoptosis; Cell Division; Cytarabine; Deferoxamine; Drug Interactions; Drug Synergism; HL-60 Cells; Humans; Iron; Leukemia, Myeloid; Receptors, Transferrin; Tumor Cells, Cultured | 1998 |
Severe infection caused by Stomatococcus mucilaginosus in a neutropenic patient: case report and review of the literature.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Gram-Positive Bacterial Infections; Humans; Idarubicin; Leukemia, Myeloid; Micrococcaceae; Mouth; Neutropenia; Opportunistic Infections; Pneumonia, Bacterial; Sepsis | 1998 |
Intensifying induction therapy in acute myeloid leukemia by an infusional chemotherapy schedule.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Etoposide; Humans; Leukemia, Myeloid; Middle Aged; Remission Induction | 1998 |
Minimum dose of fludarabine for the maximal modulation of 1-beta-D-arabinofuranosylcytosine triphosphate in human leukemia blasts during therapy.
Topics: Acute Disease; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Granulocyte Colony-Stimulating Factor; Humans; Infusions, Intravenous; Leukemia, Myeloid; Male; Middle Aged; Neoplastic Stem Cells; Phosphorylation; Time Factors; Vidarabine | 1997 |
Functional multidrug resistance phenotype associated with combined overexpression of Pgp/MDR1 and MRP together with 1-beta-D-arabinofuranosylcytosine sensitivity may predict clinical response in acute myeloid leukemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Biological Transport; Cytarabine; Daunorubicin; Doxorubicin; Drug Resistance, Multiple; Etoposide; Humans; KB Cells; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Multidrug Resistance-Associated Proteins; Phenotype; Prognosis; Treatment Outcome; Tumor Cells, Cultured | 1995 |
P-glycoprotein expression and prognostic value in acute myeloid leukemia.
Topics: Actuarial Analysis; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Child; Cohort Studies; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Female; Genes, MDR; Humans; Leukemia, Myeloid; Leukocyte Count; Male; Middle Aged; Mitoxantrone; Neoplasm Proteins; Neoplastic Stem Cells; Prognosis; Remission Induction | 1998 |
Transplantation in first remission of acute myeloid leukemia.
Topics: Acute Disease; Antimetabolites, Antineoplastic; Bone Marrow Transplantation; Cytarabine; Humans; Leukemia, Myeloid; Remission Induction; Transplantation, Autologous; Transplantation, Homologous | 1998 |
Pharmacology of cytarabine given as a continuous infusion followed by mitoxantrone with and without amsacrine/etoposide as reinduction chemotherapy for relapsed or refractory pediatric acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Amsacrine; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Child; Child, Preschool; Chromatography, High Pressure Liquid; Cytarabine; Etoposide; Female; Humans; Infant; Infusions, Intravenous; Leukemia, Myeloid; Male; Mitoxantrone; Recurrence; Remission Induction | 1998 |
Prophylactic platelet transfusion threshold during therapy for adult acute myeloid leukemia: 10,000/microL versus 20,000/microL.
Topics: Acute Disease; Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Hemorrhage; Humans; Idarubicin; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Pancytopenia; Platelet Count; Platelet Transfusion; Retrospective Studies; Spain; Thrombocytopenia | 1998 |
Structural and functional analysis of the cytidine deaminase gene in patients with acute myeloid leukaemia.
Topics: Acute Disease; Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Blotting, Southern; Cytarabine; Cytidine Deaminase; Drug Resistance, Neoplasm; Humans; Idarubicin; Leukemia, Myeloid; Middle Aged; Mutation; Polymorphism, Genetic; Reverse Transcriptase Polymerase Chain Reaction | 1998 |
Mitoxantrone, etoposide, and cytarabine plus cyclosporine for patients with relapsed or refractory acute myeloid leukemia: an Eastern Cooperative Oncology Group pilot study.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Cytarabine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Female; Gene Expression Regulation, Neoplastic; Genes, MDR; Humans; Leukemia, Myeloid; Leukopenia; Liver; Male; Middle Aged; Mitoxantrone; Recurrence; Remission Induction; Survival Rate; Treatment Outcome | 1999 |
Leukostasis followed by hemorrhage complicating the initiation of chemotherapy in patients with acute myeloid leukemia and hyperleukocytosis: a clinicopathologic report of four cases.
Topics: Acute Disease; Adult; Antimetabolites, Antineoplastic; Blood Coagulation Disorders; Cytarabine; Female; Hemorrhage; Humans; Leukemia, Myeloid; Leukocytosis; Leukostasis; Male; Middle Aged; Radiography; Thrombocytopenia | 1999 |
Management of acute myeloid leukaemia following myelodysplastic syndrome in a kidney graft recipient.
Topics: Acute Disease; Acyclovir; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Cytarabine; Etoposide; Female; Humans; Idarubicin; Imipenem; Kidney Transplantation; Leukemia, Myeloid; Middle Aged; Myelodysplastic Syndromes; Postoperative Complications; Thienamycins | 1999 |
High-dose cytarabine produces high cure rate in some AML patients.
Topics: Acute Disease; Antimetabolites, Antineoplastic; Cytarabine; Humans; Leukemia, Myeloid | 1999 |
Autologous transplantation of chemotherapy-purged PBSC collections from high-risk leukemia patients: a pilot study.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Agents; Bone Marrow Purging; Busulfan; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Disease Progression; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Humans; Length of Stay; Leukemia, Myeloid; Male; Mechlorethamine; Middle Aged; Mitoxantrone; Neoplasms, Second Primary; Neoplastic Stem Cells; Pilot Projects; Platelet Transfusion; Recurrence; Remission Induction; Risk; Salvage Therapy; Survival Analysis; Transplantation Conditioning; Transplantation, Autologous; Treatment Outcome; Vidarabine | 1999 |
A case report of neutrophilic eccrine hidradenitis in a patient receiving chemotherapy for acute myeloid leukaemia.
Topics: Acute Disease; Adult; Antimetabolites, Antineoplastic; Cytarabine; Diagnosis, Differential; Drug Eruptions; Hidradenitis; Humans; Leukemia, Myeloid; Male | 1998 |
Early detection by ultrasound scan of severe post-chemotherapy gut complications in patients with acute leukemia.
Topics: Acute Disease; Adult; Anti-Infective Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dilatation, Pathologic; Enterocolitis; Etoposide; Female; Gallbladder Diseases; Gastrointestinal Diseases; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Intubation, Gastrointestinal; Leukemia; Leukemia, Myelomonocytic, Acute; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Neutropenia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome; Ultrasonography | 1999 |
Fatal mycobacteremia caused by Mycobacterium tuberculosis in a patient with acute leukemia.
Topics: Acute Disease; Aged; Antimetabolites, Antineoplastic; Bacteremia; Cytarabine; Diagnosis, Differential; Fatal Outcome; Humans; Immunocompromised Host; Incidence; Klebsiella Infections; Leukemia, Myeloid; Lung Diseases, Fungal; Male; Neutropenia; Pneumonia, Bacterial; Tuberculosis; Tuberculosis, Pulmonary | 1999 |
Chemotherapy and donor peripheral blood progenitor cells for acute leukemia in early relapse after allogeneic bone marrow transplantation.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Etoposide; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Mitoxantrone; Recurrence; Time Factors; Tissue Donors; Transplantation Chimera; Transplantation, Homologous | 1999 |
Leukaemic blasts differ from normal bone marrow mononuclear cells and CD34+ haemopoietic stem cells in their metabolism of cytosine arabinoside.
Topics: Acute Disease; Antigens, CD34; Bone Marrow Cells; Cytarabine; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid; Monocytes | 1999 |
Evaluation of purine and pyrimidine analogues in human tumor cells from patients with low-grade lymphoproliferative disorders using the FMCA.
Topics: Acute Disease; Antineoplastic Agents; Cladribine; Cytarabine; Fluorescence; Fluorometry; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphoma, Non-Hodgkin; Survival Analysis; Vidarabine | 1999 |
GM-IVA, a short induction course for de novo acute myeloid leukemia, suitable for the elderly.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged | 1999 |
Diphtheria toxin fused to granulocyte-macrophage colony-stimulating factor and Ara-C exert synergistic toxicity against human AML HL-60 cells.
Topics: Acute Disease; Antineoplastic Agents; Cell Cycle; Cell Division; Cytarabine; Diphtheria Toxin; Drug Synergism; Granulocyte-Macrophage Colony-Stimulating Factor; HL-60 Cells; Humans; Leukemia, Myeloid; Membrane Potentials; Mitochondria; Protein Synthesis Inhibitors; Recombinant Fusion Proteins | 1999 |
A new PCR MIMIC strategy to quantify low mdr1 mRNA levels in drug resistant cell lines and AML blast samples.
Topics: Acute Disease; Adolescent; Adult; Aged; Antigens, CD34; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Chromosome Banding; Cytarabine; Daunorubicin; DNA, Complementary; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Gene Expression Regulation, Leukemic; Genes, MDR; Humans; K562 Cells; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Neoplasm Proteins; Neoplastic Stem Cells; Oligonucleotide Probes; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Sensitivity and Specificity; Tumor Cells, Cultured | 1999 |
Salvage therapy of refractory and relapsed acute leukemia with high dose mitoxantrone and high dose cytarabine.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Salvage Therapy; Survival Rate; Treatment Outcome | 1999 |
Fludarabine, cytarabine, and G-CSF (FLAG) for the treatment of acute myeloid leukemia relapsing after autologous stem cell transplantation.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Male; Middle Aged; Survival Rate; Transplantation, Autologous; Vidarabine | 1999 |
Use of peripheral blood stem cells for autologous transplantation in acute myeloid leukemia patients allows faster engraftment and equivalent disease-free survival compared with bone marrow cells.
Topics: Acute Disease; Adult; Algorithms; Antineoplastic Combined Chemotherapy Protocols; Blood Cells; Bone Marrow Transplantation; Clinical Protocols; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Etoposide; Evaluation Studies as Topic; Feasibility Studies; Female; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Leukapheresis; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Remission Induction; Time Factors; Transplantation, Autologous; Treatment Outcome | 1999 |
High-dose BEAM chemotherapy with autologous haemopoietic stem cell transplantation for Hodgkin's disease is unlikely to be associated with a major increased risk of secondary MDS/AML.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Child; Child, Preschool; Chlorambucil; Cohort Studies; Combined Modality Therapy; Cytarabine; Doxorubicin; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Hodgkin Disease; Humans; Incidence; Infant; Leukemia, Myeloid; Life Tables; Lomustine; Male; Mechlorethamine; Melphalan; Middle Aged; Myelodysplastic Syndromes; Neoplasms, Second Primary; Podophyllotoxin; Prednisolone; Prednisone; Procarbazine; Retrospective Studies; Risk; Salvage Therapy; Vinblastine; Vincristine | 1999 |
Successful low-dose cytosine arabinoside treatment in a patient with acute leukemia from idiopathic myelofibrosis.
Topics: Acute Disease; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Humans; Karyotyping; Leukemia, Myeloid; Male; Middle Aged; Primary Myelofibrosis | 1999 |
Leukaemia cell drug resistance and prognostic factors in AML.
Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Blast Crisis; Child; Child, Preschool; Cytarabine; Cytogenetic Analysis; Daunorubicin; Drug Resistance, Neoplasm; Female; Humans; Infant; Leukemia, Myeloid; Male; Middle Aged; Multivariate Analysis; Prognosis; Tetrazolium Salts | 1999 |
Expression of Bcl-2-related genes in normal and AML progenitors: changes induced by chemotherapy and retinoic acid.
Topics: Acute Disease; Antigens, CD34; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; bcl-Associated Death Protein; bcl-X Protein; Carrier Proteins; Cytarabine; Down-Regulation; Flow Cytometry; Gene Expression; Genes, bcl-2; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid; Neoplasm, Residual; Phosphorylation; Phosphoserine; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; Survival Rate; Tretinoin; Tumor Cells, Cultured | 1999 |
Cytidine deaminase - the methodological relevance of AraC deamination for ex vivo experiments using cultured cell lines, fresh leukemic blasts, and normal bone marrow cells.
Topics: Acute Disease; Blast Crisis; Bone Marrow Cells; Cell Count; Cytarabine; Cytidine Deaminase; Deamination; Humans; Leukemia, Myeloid; Tumor Cells, Cultured | 1999 |
Acute minimally differentiated myeloid leukemia (M0) with inv(3)(q21q26).
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cell Differentiation; Chromosome Inversion; Chromosomes, Human, Pair 3; Cytarabine; Daunorubicin; Fatal Outcome; Humans; Leukemia, Myeloid; Male; Middle Aged; Prednisolone | 1999 |
Mild pre-transplant cardiomyopathy may not impair long-term quality of life after bone marrow transplantation.
Topics: Acute Disease; Anthracyclines; Bone Marrow Transplantation; Cardiomyopathies; Child; Cytarabine; Daunorubicin; Electroencephalography; Graft vs Host Disease; Humans; Immunosuppressive Agents; Karnofsky Performance Status; Leukemia, Myeloid; Male; Quality of Life; Transplantation, Homologous | 2000 |
Palliative cytoreduction in refractory acute leukemia: a retrospective study of 57 adult patients.
Topics: Acute Disease; Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Diarrhea; Female; Humans; Injections, Intravenous; Injections, Subcutaneous; Leukemia; Leukocyte Count; Male; Mercaptopurine; Methotrexate; Middle Aged; Nausea; Palliative Care; Retrospective Studies; Stomatitis; Thioguanine | 2000 |
Granulocyte macrophage--colony stimulating factor (GM-CSF) as adjunct in induction therapy of acute myeloid leukemia.
Topics: Acute Disease; Adjuvants, Immunologic; Adolescent; Adult; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Fever; Follow-Up Studies; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Male; Middle Aged; Neoplasm Recurrence, Local; Neutropenia; Remission Induction | 1999 |
Liposomal Bcl-2 antisense oligonucleotides enhance proliferation, sensitize acute myeloid leukemia to cytosine-arabinoside, and induce apoptosis independent of other antiapoptotic proteins.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Apoptosis; Bone Marrow Cells; Cell Division; Cells, Cultured; Cytarabine; Female; Genes, bcl-2; HL-60 Cells; Humans; Leukemia, Myeloid; Liposomes; Male; Middle Aged; Oligodeoxyribonucleotides, Antisense; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured | 2000 |
Deletion of the multidrug resistance-associated protein (MRP1) gene in acute myeloid leukemia with inversion of chromosome 16 has no prognostic impact.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Chromosome Inversion; Chromosomes, Human, Pair 16; Cytarabine; DNA-Binding Proteins; Etoposide; Gene Deletion; Humans; Idarubicin; In Situ Hybridization, Fluorescence; Leukemia, Myeloid; Mitoxantrone; Multidrug Resistance-Associated Proteins; MutS Homolog 3 Protein; Prognosis; Prospective Studies; Recurrence; Remission Induction | 2000 |
Fludarabine and high dose cytarabine (FLA): a well tolerated salvage regimen in acute myeloid leukaemia.
Topics: Acute Disease; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Cytarabine; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Retrospective Studies; Salvage Therapy; Vidarabine | 1999 |
The pharmacodynamic basis for the increased antileukaemic efficacy of cytosine arabinoside-based treatment regimens in acute myeloid leukaemia with a high proliferative activity.
Topics: Acute Disease; Adult; Aged; Cell Division; Cytarabine; Cytidine Deaminase; Deoxycytidine Kinase; DNA; Female; Half-Life; Humans; Immunosuppressive Agents; Leukemia, Myeloid; Linear Models; Lymphocytes; Male; Middle Aged; Statistics, Nonparametric; Time Factors | 2000 |
Serum ICAM-1 concentrations following conventional dose consolidation chemotherapy for acute myeloid leukemia and after high dose chemotherapy with autologous haematopoietic stem cell rescue.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Breast Neoplasms; Combined Modality Therapy; Cytarabine; Etoposide; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Intercellular Adhesion Molecule-1; Leukemia, Myeloid; Leukocyte Count; Male; Middle Aged; Neoplasm Proteins; Neutropenia; Neutrophils; Recombinant Proteins; Solubility | 2000 |
Expression of CD11b/CD18 on neutrophils after consolidation chemotherapy for acute myeloid leukemia and after high dose chemotherapy with autologous haematopoietic stem cell transplantation.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Breast Neoplasms; CD18 Antigens; Combined Modality Therapy; Cytarabine; Etoposide; Female; Filgrastim; Gene Expression Regulation, Leukemic; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Macrophage-1 Antigen; Male; Melphalan; Middle Aged; Neoplasm Proteins; Neutropenia; Recombinant Proteins; Remission Induction | 2000 |
Combination regimen of cladribine (2-chlorodeoxyadenosine), cytarabine and G-CSF (CLAG) as induction therapy for patients with relapsed or refractory acute myeloid leukemia.
Topics: Acute Disease; Adult; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cytarabine; Disease-Free Survival; Drug Evaluation; Female; Fever; Granulocyte Colony-Stimulating Factor; Humans; Infections; Leukemia, Myeloid; Male; Middle Aged; Neutropenia; Recurrence; Remission Induction; Survival Rate; Treatment Outcome | 2000 |
A novel RT-PCR-based protein activity truncation assay for direct assessment of deoxycytidine kinase in small numbers of purified leukemic cells.
Topics: Acute Disease; Animals; Antimetabolites, Antineoplastic; Bone Marrow Cells; Cytarabine; Deoxycytidine Kinase; Drug Resistance, Neoplasm; Humans; Leukemia, Myeloid; Phytohemagglutinins; Protein Biosynthesis; Rats; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocytes; Transcription, Genetic; Tumor Cells, Cultured | 2000 |
Combination chemotherapy with risk factor-adjusted dose attenuation for high-risk myelodysplastic syndrome and resulting leukemia in the multicenter study of the Japan Adult Leukemia Study Group (JALSG): results of an interim analysis.
Topics: Acute Disease; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Female; Humans; Idarubicin; Japan; Karyotyping; Leukemia, Myeloid; Male; Middle Aged; Myelodysplastic Syndromes; Remission Induction; Risk Factors; Survival Rate | 2000 |
[Poor response in patients with de novo acute myeloid leukemia and erythroblastic or megakaryocytic dysplasia to treatment with standard doses of cytosine arabinoside and daunorubicin].
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Daunorubicin; Erythroblasts; Humans; Leukemia, Myeloid; Megakaryocytes; Middle Aged | 1999 |
Nucleus labeling or membrane labeling for studying the proliferation of drug treated cells?
Topics: Acute Disease; Antineoplastic Agents; Cell Cycle; Cell Division; Cell Membrane; Cell Membrane Permeability; Cell Nucleus; Cytarabine; Daunorubicin; DNA, Neoplasm; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluorescent Dyes; Humans; K562 Cells; Leukemia, Myeloid; Propidium | 2000 |
Antileukemic drugs increase death receptor 5 levels and enhance Apo-2L-induced apoptosis of human acute leukemia cells.
Topics: Acute Disease; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Apoptotic Protease-Activating Factor 1; BH3 Interacting Domain Death Agonist Protein; Carrier Proteins; Caspase 3; Caspase 8; Caspase 9; Caspases; Cytarabine; Cytochrome c Group; Doxorubicin; Etoposide; HL-60 Cells; Humans; Jurkat Cells; Leukemia; Membrane Glycoproteins; Proteins; Proto-Oncogene Proteins c-bcl-2; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53; U937 Cells; Up-Regulation | 2000 |
Cytosine arabinoside induced acute interstitial nephritis in a patient treated for refractory anemia with excess of blasts in transformation.
Topics: Acute Disease; Aged; Anemia, Refractory, with Excess of Blasts; Antimetabolites, Antineoplastic; Cytarabine; Female; Humans; Nephritis, Interstitial | 2000 |
Long-term survival after induction therapy with idarubicin and cytosine arabinoside for de novo acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Cytarabine; Disease-Free Survival; Female; Humans; Idarubicin; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Multivariate Analysis; Remission Induction; Survival Rate | 2000 |
Chemotherapy and marrow transplantation for congenital leukaemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Etoposide; Female; Humans; Infant, Newborn; Leukemia; Methotrexate; Mitoxantrone; Prednisolone; Treatment Outcome; Vincristine | 2001 |
Blasts from elderly acute myeloid leukemia patients are characterized by low levels of culture- and drug-induced apoptosis.
Topics: Acute Disease; Adult; Aged; Aging; Antibiotics, Antineoplastic; Antigens, CD34; Antimetabolites, Antineoplastic; Apoptosis; Bone Marrow Cells; Cell Cycle; Cytarabine; Daunorubicin; G2 Phase; Humans; Leukemia, Myeloid; Middle Aged; Mitosis; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-bcl-2; S Phase; Tumor Cells, Cultured | 2001 |
De novo acute myeloid leukemia in the elderly; a consistent fraction of long-term survivors by standard-dose chemotherapy.
Topics: Acute Disease; Aged; Aged, 80 and over; Aging; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Karyotyping; Leukemia, Myeloid; Male; Mercaptopurine; Middle Aged; Prognosis; Treatment Outcome; Tretinoin | 2001 |
Acute myeloid leukemia and lung cancer occurring in a chronic lymphocytic leukemia patient treated with fludarabine and autologous peripheral blood stem-cell transplantation.
Topics: Acute Disease; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cytarabine; Etoposide; Fatal Outcome; Genetic Predisposition to Disease; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid; Lung Neoplasms; Male; Middle Aged; Neoplasm, Residual; Neoplasms, Multiple Primary; Neoplasms, Second Primary; Recombinant Proteins; Risk; Smoking; Transplantation Conditioning; Transplantation, Autologous; Vidarabine | 2000 |
Fludarabine, cytarabine and topotecan (FLAT) as induction therapy for acute myeloid leukemia in the elderly: a preliminary report.
Topics: Acute Disease; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Drug Evaluation; Female; Follow-Up Studies; Humans; Leukemia, Myeloid; Male; Middle Aged; Remission Induction; Topotecan; Vidarabine | 2001 |
Mutations in ras proto-oncogenes are associated with lower mdr1 gene expression in adult acute myeloid leukaemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; ATP-Binding Cassette Transporters; Case-Control Studies; Cytarabine; Daunorubicin; Female; Gene Expression; Genes, MDR; Genes, ras; Humans; Leukemia, Myeloid; Male; Middle Aged; Multidrug Resistance-Associated Proteins; Mutation; Prospective Studies; Protein Tyrosine Phosphatases; Receptor-Like Protein Tyrosine Phosphatases, Class 4; Receptors, Cell Surface; Reverse Transcriptase Polymerase Chain Reaction | 2001 |
Action of topoisomerase targeting drugs on non-Hodgkin's lymphoma and leukemia. Correlation of clinical and cell culture studies.
Topics: Acute Disease; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase I as Topic; Cytarabine; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA-Binding Proteins; DNA, Neoplasm; Enzyme Inhibitors; Etoposide; Humans; Isoenzymes; Leukemia; Leukocytes; Lymphoma, Non-Hodgkin; Mitoxantrone; Polymerase Chain Reaction; RNA, Messenger; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Topotecan | 2000 |
Combination chemotherapy utilizing continuous infusion of intermediate-dose cytarabine for refractory or recurrent acute myeloid leukemia.
Topics: Actuarial Analysis; Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Resistance, Neoplasm; Female; Humans; Infusions, Intravenous; Leukemia, Myeloid; Male; Middle Aged; Recurrence; Remission Induction; Salvage Therapy; Survival Rate; Treatment Outcome | 2001 |
Transfusion of peripheral blood stem cells from donor homozygous for a shared HLA-haplotype: avoiding fatal transfusion-associated graft-versus-host disease while preserving anti-leukemic effect.
Topics: Acute Disease; Adult; Blood Transfusion; Cytarabine; Fatal Outcome; Graft vs Host Disease; Haplotypes; Hematopoietic Stem Cell Transplantation; HLA Antigens; Homozygote; Humans; Idarubicin; Leukemia, Myeloid; Male | 2001 |
Combination chemotherapy of intermediate-dose cytarabine, idarubicin, plus etoposide and subsequent mobilized donor leukocyte infusion for relapsed acute leukemia after allogeneic bone marrow transplantation.
Topics: Actuarial Analysis; Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Disease-Free Survival; Etoposide; Female; Graft vs Host Disease; Hematopoietic Stem Cell Mobilization; Humans; Idarubicin; Leukemia; Leukocyte Transfusion; Male; Recurrence; Survival Rate; Transplantation, Homologous | 2001 |
The combination of chemotherapy and systemic immunotherapy with soluble B7-immunoglobulin G leads to cure of murine leukemia and lymphoma and demonstration of tumor-specific memory responses.
Topics: Acute Disease; Animals; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; B7-1 Antigen; B7-2 Antigen; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Doxorubicin; Female; Immunoglobulin G; Immunologic Memory; Immunotherapy; Leukemia, Myeloid; Leukemia, Radiation-Induced; Lymphoma, Non-Hodgkin; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, SCID; Neoplasm Transplantation; Recombinant Fusion Proteins; T-Lymphocytes; Thymus Neoplasms | 2001 |
Neutrophilic eccrine hidradenitis in two neutropaenic patients.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Hidradenitis; Humans; Leukemia, Myeloid; Mitoxantrone | 2001 |
Pretreatment leukaemia cell drug resistance is correlated to clinical outcome in acute myeloid leukaemia.
Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Etoposide; Female; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Neoplastic Stem Cells; Prognosis; Remission Induction; Survival Analysis; Thioguanine; Treatment Outcome; Tumor Cells, Cultured | 2001 |
Effect of granulocyte colony-stimulating factor on chemotherapeutic activity of cytosine arabinoside in acute leukemic cell lines.
Topics: Acute Disease; Antineoplastic Agents; Apoptosis; Cell Count; Cell Division; Cytarabine; Drug Synergism; Flow Cytometry; Granulocyte Colony-Stimulating Factor; Humans; Leukemia; Tumor Cells, Cultured | 2001 |
Fludarabine and cytarabine as a sequential infusion regimen for treatment of adults with recurrent, refractory or poor prognosis acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Cytarabine; Cytogenetic Analysis; Disease-Free Survival; Drug Administration Schedule; Female; Hematologic Diseases; Humans; Infections; Infusion Pumps; Leukemia; Lung Diseases; Male; Middle Aged; Nervous System Diseases; Prognosis; Recurrence; Retrospective Studies; Survival Rate; Treatment Outcome; Vidarabine | 2001 |
Patterns of failure with increasing intensification of induction chemotherapy for acute myeloid leukaemia.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Australia; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Administration Schedule; Etoposide; Humans; Incidence; Leukemia, Myeloid; Middle Aged; Proportional Hazards Models; Randomized Controlled Trials as Topic; Remission Induction; Risk Assessment; Survival Rate; Time Factors; Treatment Failure | 2001 |
Molecular remission following high-dose hydroxyurea and fludarabine plus cytarabine in a patient with simultaneous acute myeloid leukemia and low-grade lymphoma.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Hydroxyurea; Leukemia, Myeloid; Lymphoma; Neoplasms, Multiple Primary; Remission Induction; Vidarabine | 2001 |
Improved efficiency of remission induction facilitates autologous BMT harvesting and improves overall survival in adults with AML: 108 patients treated at a single institution.
Topics: Acute Disease; Adolescent; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Etoposide; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Remission Induction; Retrospective Studies; Survival Rate; Transplantation, Autologous; Treatment Outcome | 2001 |
Consolidation treatment with autologous peripheral blood progenitor cell transplantation in acute myeloid leukemia: a single center experience.
Topics: Acute Disease; Adult; Antimetabolites, Antineoplastic; Cytarabine; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Male; Middle Aged; Transplantation, Autologous | 2001 |
Impact of treatment on the outcome of acute myeloid leukemia with inversion 16: a single institution's experience.
Topics: Acute Disease; Adolescent; Antineoplastic Agents; Bone Marrow Transplantation; Child; Child, Preschool; Chromosome Inversion; Chromosomes, Human, Pair 16; Cladribine; Combined Modality Therapy; Cytarabine; Drug Therapy, Combination; Etoposide; Female; Humans; Infant; Leukemia, Megakaryoblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Male; Prognosis; Treatment Outcome | 2001 |
Bone marrow stromal cells regulate caspase 3 activity in leukemic cells during chemotherapy.
Topics: Acute Disease; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Bone Marrow Cells; Caspase 3; Caspases; Cell Survival; Coculture Techniques; Cytarabine; Etoposide; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stromal Cells; Tumor Cells, Cultured | 2001 |
Expression of high Km 5'-nucleotidase in leukemic blasts is an independent prognostic factor in adults with acute myeloid leukemia.
Topics: 5'-Nucleotidase; Acute Disease; Adult; Aged; Antimetabolites, Antineoplastic; Cohort Studies; Cytarabine; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Prognosis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Survival Rate; Transcription, Genetic; Treatment Outcome | 2001 |
Unrelated cord blood transplantation for adult patients with myelodysplastic syndrome-related secondary acute myeloid leukaemia.
Topics: Acute Disease; Adult; Antimetabolites, Antineoplastic; Cytarabine; Female; Fetal Blood; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Male; Middle Aged; Myelodysplastic Syndromes; Prospective Studies; Survival Rate; Transplantation, Homologous; Whole-Body Irradiation | 2001 |
Close correlation of 1-beta-D-arabinofuranosylcytosine 5'-triphosphate, an intracellular active metabolite, to the therapeutic efficacy of N(4)-behenoyl-1-beta-D-arabinofuranosylcytosine therapy for acute myelogenous leukemia.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Arabinofuranosylcytosine Triphosphate; Area Under Curve; Biotransformation; Cytarabine; Female; Humans; Infusions, Intravenous; Intracellular Fluid; Leukemia, Myeloid; Male; Middle Aged; Neoplastic Stem Cells; Prodrugs; Remission Induction; Sensitivity and Specificity; Treatment Outcome | 2001 |
In vitro effects of dexrazoxane (Zinecard) and classical acute leukemia therapy: time to consider expanded clinical trials?
Topics: Acute Disease; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Cell Death; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Humans; Inhibitory Concentration 50; Leukemia; Mitoxantrone; Razoxane; Tumor Cells, Cultured | 2001 |
Remission induction therapy: the more intensive the better?
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid; Middle Aged; Remission Induction; Thioguanine | 2001 |
PK11195, a peripheral benzodiazepine receptor ligand, chemosensitizes acute myeloid leukemia cells to relevant therapeutic agents by more than one mechanism.
Topics: Acute Disease; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Cytarabine; Daunorubicin; DNA, Neoplasm; Drug Resistance, Multiple; Flow Cytometry; Humans; Isoquinolines; Leukemia, Myeloid; Ligands; Receptors, GABA-A; Tumor Cells, Cultured | 2002 |
Treatment of relapse after allogeneic bone marrow transplantation with reduced intensity conditioning (FLAG +/- Ida) and second allogeneic stem cell transplant.
Topics: Acute Disease; Adult; Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Disease-Free Survival; Female; Filgrastim; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia; Leukemia, Myeloid; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recombinant Proteins; Recurrence; Reoperation; Retrospective Studies; Survival Rate; Transplantation Conditioning; Transplantation, Homologous; Vidarabine | 2001 |
Evaluation of the clinical relevance of the expression and function of P-glycoprotein, multidrug resistance protein and lung resistance protein in patients with primary acute myelogenous leukemia.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Marrow Transplantation; Calcium Channel Blockers; Carbocyanines; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Fluoresceins; Fluorescent Dyes; Genistein; Humans; Idarubicin; Immunophenotyping; Leukemia, Myeloid; Male; Middle Aged; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Probenecid; Prognosis; Prospective Studies; Rhodamine 123; Survival Analysis; Tumor Cells, Cultured; Vault Ribonucleoprotein Particles; Verapamil | 2002 |
Standard versus alternative myeloablative conditioning regimens in allogeneic hematopoietic stem cell transplantation for high-risk acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Busulfan; Child; Child, Preschool; Cyclophosphamide; Cyclosporine; Cytarabine; Disease-Free Survival; Etoposide; Female; Graft Survival; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Immunosuppressive Agents; Infant; Leukemia; Life Tables; Male; Methylprednisolone; Middle Aged; Premedication; Retrospective Studies; Risk; Survival Analysis; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Whole-Body Irradiation | 2002 |
Functional role of alternatively spliced deoxycytidine kinase in sensitivity to cytarabine of acute myeloid leukemic cells.
Topics: Acute Disease; Alternative Splicing; Animals; Bone Marrow Cells; Cell Survival; Cytarabine; Deoxycytidine Kinase; Dose-Response Relationship, Drug; Drug Resistance; Humans; Leukemia, Myeloid; Protein Isoforms; Rats; Transduction, Genetic; Tumor Cells, Cultured | 2002 |
Hematopoietic cell transplantation beyond first remission.
Topics: Acute Disease; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Comorbidity; Cyclosporine; Cytarabine; Daunorubicin; Disease-Free Survival; Follow-Up Studies; Graft Survival; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Nuclear Family; Prospective Studies; Randomized Controlled Trials as Topic; Remission Induction; Salvage Therapy; Survival Rate; Tissue Donors; Transplantation, Homologous; Treatment Outcome; Vidarabine | 2002 |
Prognosis of elderly patients with acute myelogenous leukemia: analysis of 126 AML cases.
Topics: Acute Disease; Age Factors; Aged; Allopurinol; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cholinesterases; Cytarabine; Daunorubicin; Disease Progression; Female; Humans; Japan; Karyotyping; Leukemia, Myeloid; Life Tables; Male; Mercaptopurine; Middle Aged; Myelodysplastic Syndromes; Neoplasm Proteins; Prognosis; Remission Induction; Risk Factors; Survival Analysis; Survival Rate | 2002 |
FAB M4 and high CD14 surface expression is associated with high cellular resistance to Ara-C and daunorubicin: implications for clinical outcome in acute myeloid leukaemia.
Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Amsacrine; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cohort Studies; Cytarabine; Daunorubicin; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Idarubicin; Leukemia, Myeloid; Leukemia, Myelomonocytic, Acute; Lipopolysaccharide Receptors; Male; Middle Aged; Mitoxantrone; Multivariate Analysis; Neoplastic Stem Cells; Thioguanine; Treatment Outcome | 2001 |
Immunotherapy by non-myeloablative stem cell transplantation: study of the immune reconstitution. Arguments for distinct cell subsets in skin and blood.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Blood; Blood Cells; Carmustine; CD8-Positive T-Lymphocytes; Clone Cells; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Doxorubicin; Female; Graft Survival; Graft vs Host Reaction; Graft vs Leukemia Effect; Hematopoietic Stem Cell Transplantation; Humans; Immunophenotyping; Immunotherapy; Leukemia, Myeloid; Male; Middle Aged; Minisatellite Repeats; Multiple Myeloma; Prednisone; Receptors, Antigen, T-Cell, alpha-beta; Skin; T-Lymphocyte Subsets; Transplantation Conditioning; Transplantation, Homologous; Vincristine; Whole-Body Irradiation | 2000 |
High-dose cytarabine as consolidation treatment for patients with acute myeloid leukemia with t(8;21).
Topics: Acute Disease; Adolescent; Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Prospective Studies; Survival Analysis; Translocation, Genetic; Treatment Outcome | 2002 |
Potential mechanisms of resistance to cytarabine in AML patients.
Topics: 5'-Nucleotidase; Acute Disease; Adult; Aged; Antigens, Neoplasm; Antimetabolites, Antineoplastic; Cytarabine; Cytidine Deaminase; Deoxycytidine Kinase; Disease-Free Survival; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA-Binding Proteins; Drug Resistance, Neoplasm; Equilibrative Nucleoside Transporter 1; Female; France; Humans; Leukemia, Myeloid; Life Tables; Male; Membrane Transport Proteins; Middle Aged; Neoplasm Proteins; Neoplastic Stem Cells; Proportional Hazards Models; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; Survival Analysis | 2002 |
In vivo use of all-trans retinoic acid prior to induction chemotherapy improves complete remission rate and increases rhodamine 123 uptake in patients with de novo acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antigens, CD; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Case-Control Studies; Cytarabine; Drug Resistance, Multiple; Etoposide; Female; Fluorescent Dyes; Humans; Idarubicin; Immunophenotyping; Leukemia, Myeloid; Leukocyte Count; Male; Middle Aged; Proto-Oncogene Proteins c-bcl-2; Remission Induction; Rhodamine 123; Treatment Outcome; Tretinoin | 2002 |
In vivo mechanisms of resistance to cytarabine in acute myeloid leukaemia.
Topics: 5'-Nucleotidase; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biomarkers; Cytarabine; Cytidine Deaminase; Disease-Free Survival; DNA Polymerase I; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Drug Resistance, Neoplasm; Equilibrative Nucleoside Transporter 1; Female; Humans; Immunosuppressive Agents; Leukemia, Myeloid; Lymphocytes; Male; Membrane Transport Proteins; Middle Aged; Multivariate Analysis; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction | 2002 |
Heterogeneity of morphological, cytochemical, and cytogenetic features in the blastic phase of chronic granulocytic leukemia.
Topics: Acute Disease; Adult; Alkaline Phosphatase; Aneuploidy; Biopsy; Bone Marrow; Bone Marrow Cells; Cell Nucleus; Child; Chromosome Aberrations; Cytarabine; Cytoplasm; Female; Histocytochemistry; Humans; Leukemia, Myeloid; Male; Microscopy, Electron; Middle Aged; Mitochondria; Organoids; Peroxidases; Prednisone; Remission, Spontaneous; Staining and Labeling; Thioguanine; Vincristine | 1975 |
Acute leukemia in children: experience in Saskatchewan in 1966-72.
Topics: Acute Disease; Adolescent; Antineoplastic Agents; Blood Transfusion; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Follow-Up Studies; Hematopoietic Stem Cells; Humans; Leukemia; Leukemia, Lymphoid; Palliative Care; Prednisone; Saskatchewan; Vincristine | 1975 |
[New drugs for the therapy of acute leukemia].
Topics: Acute Disease; Antineoplastic Agents; Azacitidine; Cytarabine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Guanazole; Humans; Leukemia; Lomustine; Peptichemio; Podophyllotoxin; Razoxane; Zinostatin | 1975 |
Quality and quantity of survival in acute myeloid leukaemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Allopurinol; Bacterial Infections; Cytarabine; Daunorubicin; Drug Therapy, Combination; Focal Infection, Dental; Follow-Up Studies; Humans; Length of Stay; Leukemia, Myeloid, Acute; Mercaptopurine; Middle Aged; Philosophy; Quality of Life; Remission, Spontaneous | 1975 |
[Experiences with polychemotherapy of acute leukemias in adults with special reference to the COAP combination].
Topics: Acute Disease; Adolescent; Adult; Aged; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Middle Aged; Prednisone; Vincristine | 1975 |
Biochemical pharmacology of cytidine analog metabolism in human leukemic cells.
Topics: Acute Disease; Adolescent; Adult; Aged; Azacitidine; Cytarabine; Cytidine Deaminase; Humans; In Vitro Techniques; Leukemia; Middle Aged; Phosphotransferases; Uridine Kinase | 1975 |
The therapy of acute leukemia in the adult: a progress report.
Topics: Acute Disease; Adult; Antineoplastic Agents; Azacitidine; Blood Transfusion; Cytarabine; Daunorubicin; Dexamethasone; Etoposide; Granulocytes; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Patient Isolation; Platelet Transfusion; Pneumonia; Prednisone; Pyrimethamine; Remission, Spontaneous; Thioguanine; Vincristine; Zinostatin | 1976 |
[Chemotherapy of acute leukemia with cyclocytidine, with special reference to serum ara-C deaminase activity (author's transl)].
Topics: Acute Disease; Adolescent; Adult; Aged; Aminohydrolases; Ancitabine; Antineoplastic Agents; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged; Remission, Spontaneous | 1977 |
Treatment of acute nonlymphocytic leukemia (ANLL) in elderly patients. Results of a multicentric study.
Topics: Acute Disease; Aged; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Middle Aged; Remission, Spontaneous; Thioguanine | 1979 |
Clinical application of bone marrow culture from patients with acute leukemia.
Topics: Acute Disease; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Cytarabine; Humans; Leukemia; Methods | 1976 |
Acute hypereosinophilic syndrome. Successful treatment with vincristine, cytarabine, and prednisone.
Topics: Acute Disease; Adult; Cardiomegaly; Confusion; Cytarabine; Drug Therapy, Combination; Eosinophilia; Female; Humans; Prednisone; Retinal Hemorrhage; Syndrome; Vincristine | 1979 |
On the mode of decrease of leukemic cells during treatment of acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aminobiphenyl Compounds; Antineoplastic Agents; Asparaginase; Bone Marrow; Cell Survival; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Leukocyte Count; Male; Mercaptopurine; Mesylates; Methotrexate; Middle Aged; Neutrophils; Prednisolone; Time Factors; Zinostatin | 1976 |
Blindness during remission in two patients with acute lymphoblastic leukemia: a possible complication of multimodality therapy.
Topics: Acute Disease; Adult; Blindness; Brain; Child, Preschool; Cytarabine; Drug Therapy, Combination; Female; Humans; Injections, Spinal; Leukemia, Lymphoid; Methotrexate; Optic Nerve; Radiotherapy; Remission, Spontaneous | 1977 |
Current concepts in acute leukemia.
Topics: Acute Disease; Adult; Age Factors; BCG Vaccine; Cytarabine; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Humans; Leukemia; Leukemia, Myeloid, Acute; Middle Aged; Prednisone; Vincristine | 1977 |
Therapy of acute nonlymphocytic leukemia: I. Clinical aspects.
Topics: Acute Disease; Aged; Blood Transfusion; Cytarabine; Daunorubicin; Doxorubicin; Female; Humans; Leukemia; Male; Middle Aged; Pancytopenia | 1979 |
[Therapy of acute nonlymphocytic leukemia: 2. Biological characteristics and prediction of response].
Topics: Acute Disease; Age Factors; Cytarabine; Daunorubicin; Doxorubicin; Humans; Infections; Leukemia | 1979 |
Serial studies on in vitro colony formation in patients with acute leukemia in relation to the maintenance of remission.
Topics: Acute Disease; Adult; Child; Colony-Forming Units Assay; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisolone; Remission, Spontaneous | 1978 |
Leukemias induced by ethylnitrosourea in Wistar rats: incidence and chemotherapy.
Topics: Acute Disease; Animals; Cytarabine; Doxorubicin; Drug Therapy, Combination; Ethylnitrosourea; Leukemia, Experimental; Leukemia, Myeloid; Leukocyte Count; Male; Nitrosourea Compounds; Rats; Vincristine | 1979 |
Engraftment of RH-positive marrow in a recipient with RH antibody.
Topics: Acute Disease; Adult; Blood Group Incompatibility; Bone Marrow Cells; Bone Marrow Transplantation; Cell Survival; Cyclophosphamide; Cytarabine; Graft Survival; Humans; Hydroxyurea; Injections, Spinal; Isoantibodies; Leukemia, Lymphoid; Male; Methotrexate; Patient Isolators; Rh-Hr Blood-Group System | 1977 |
[Monocytic leukemia. Analysis of clinical and hematological data in 21 patients (author's transl)].
Topics: Acute Disease; Adolescent; Adult; Aged; Bone Marrow Examination; Chronic Disease; Cytarabine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Female; Histocytochemistry; Humans; Leukemia, Myeloid; Male; Methotrexate; Middle Aged; Monocytes; Sternum; Vincristine | 1977 |
Aggressive therapy in acute respiratory failure from leukemic pulmonary infiltrates.
Topics: Acute Disease; Adult; Cytarabine; Doxorubicin; Female; Humans; Leukemia; Lung Neoplasms; Oxygen; Respiration, Artificial; Respiratory Insufficiency | 1979 |
Continuous intravenous arabinosyl cytosine infusions delivered by a new portable infusion system.
Topics: Acute Disease; Adolescent; Adult; Aged; Ambulatory Care; Cytarabine; Evaluation Studies as Topic; Humans; Infusions, Parenteral; Leukemia; Middle Aged; Safety; Time Factors | 1979 |
Remission induction and remission maintenance in adult acute nonlymphocytic leukemia employing a modified cytostatic (COAP) regimen.
Topics: Acute Disease; Adolescent; Adult; Aged; Cyclophosphamide; Cytarabine; Female; Humans; Leukemia; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Time Factors; Vincristine | 1979 |
Daunorubicin, cytosine arabinoside and 6-thioguanine (DAT) combination chemotherapy for the treatment of acute non-lymphocytic leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Agents; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Middle Aged; Thioguanine | 1979 |
High dose cytosine arabinoside (HDARAC) in refractory acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Agents; Central Nervous System; Child; Child, Preschool; Cytarabine; Digestive System; Drug Resistance; Female; Humans; Infusions, Parenteral; Leukemia; Male; Middle Aged; Remission, Spontaneous; Time Factors | 1979 |
[Results of treating acute nonlymphoblastic leukaemia in adults (author's transl)].
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Cytarabine; Daunorubicin; Female; Humans; Leukemia; Male; Middle Aged | 1979 |
[Varicella infections in children with acute leukemia (author's transl)].
Topics: Acute Disease; Adolescent; Age Factors; Chickenpox; Child; Child, Preschool; Cytarabine; Female; Humans; Leukemia; Male | 1979 |
[Tests of cell mediated immunity during the treatment of acute leukemia in infants (author's transl)].
Topics: Acute Disease; Adolescent; Child; Child, Preschool; Cytarabine; Daunorubicin; Humans; Immune Adherence Reaction; Immunity, Cellular; Infant; Leukemia; Mercaptopurine; Prednisolone; Vincristine | 1977 |
Treating acute nonlymphocytic leukemia.
Topics: Acute Disease; Aged; Anemia; Antineoplastic Agents; Bacterial Infections; Blood Transfusion; Cytarabine; Drug Therapy, Combination; Hemorrhage; Humans; Leukemia; Middle Aged; Mycoses; Remission, Spontaneous | 1978 |
Acute leukemia in pregnancy. Successful delivery after cytarabine and doxorubicin.
Topics: Acute Disease; Adult; Cesarean Section; Cytarabine; Doxorubicin; Female; Humans; Leukemia; Pregnancy; Pregnancy Complications, Hematologic; Remission, Spontaneous | 1978 |
[Progressive pulmonary fibrosis during combination chemotherapy with BCNU (author's transl)].
Topics: Acute Disease; Carmustine; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia; Middle Aged; Pulmonary Fibrosis | 1978 |
[A case of leukemia obtained complete remission after delivery (author's transl)].
Topics: Acute Disease; Adult; Cytarabine; Daunorubicin; Female; Humans; Leukemia; Prednisolone; Pregnancy; Pregnancy Complications, Hematologic; Remission, Spontaneous; Vincristine | 1978 |
[Treatment results of therapy resistant acute leukemias with 7 cystostatic agents (TRAMPCO-scheme)].
Topics: Acute Disease; Adolescent; Adult; Aged; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Resistance; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Methotrexate; Middle Aged; Prednisolone; Thioguanine; Vincristine | 1978 |
Cytosine arabinoside modulation of the mitotic index in treatment of adult acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged; Mitosis; Mitotic Index | 1978 |
Rapid remission induction in adult acute non-lymphoblastic leukaemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Cytarabine; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Humans; Leukemia; Male; Middle Aged; Podophyllotoxin; Remission, Spontaneous; Sepsis; Time Factors | 1978 |
[Therapeutic results in adult acute non-lymphoblastic leukemia].
Topics: Acute Disease; Adult; Cytarabine; Daunorubicin; Female; Humans; Leukemia; Male | 1978 |
[Therapeutic results in patients with acute leukemia].
Topics: Acute Disease; Adolescent; Adult; Blood Platelets; Blood Transfusion; Cytarabine; Daunorubicin; Humans; Leukemia; Middle Aged; Prognosis | 1978 |
Further local experience in the treatment of acute non-lymphoblastic leukaemia.
Topics: Acute Disease; Adult; Aged; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia; Middle Aged; Prednisone; Thioguanine; Vincristine | 1978 |
Advances in the management of acute nonlymphocytic leukemia.
Topics: Acute Disease; Anti-Bacterial Agents; Blood Transfusion; Cytarabine; Daunorubicin; Drug Therapy, Combination; Granulocytes; Hemorrhage; Humans; Immunotherapy; Infection Control; Infections; Kidney Diseases; Leukemia; Platelet Transfusion; Transplantation, Homologous | 1976 |
[Adverse effects and complications of intensive therapy of acute leukemia in adults using the OAP scheme (oncovin, cytosine arabinoside, prednisolone)].
Topics: Acute Disease; Adult; Cytarabine; Drug Therapy, Combination; Humans; Leukemia; Prednisolone; Vincristine | 1977 |
Treatment of acute nonlymphocytic leukemia in elderly patients: a prospective study of intensive chemotherapy.
Topics: Acute Disease; Aged; Antineoplastic Agents; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Infections; Length of Stay; Leukemia; Male; Middle Aged; Prednisone; Prospective Studies; Remission, Spontaneous; Thioguanine; Time Factors | 1977 |
Treatment of acute nonlymphoblastic leukemia in children with a multiple-drug protocol.
Topics: Acute Disease; Adolescent; Antineoplastic Agents; Asparaginase; Child; Child, Preschool; Cytarabine; Doxorubicin; Drug Therapy, Combination; Female; Humans; Infant; Leukemia; Male; Meningeal Neoplasms; Remission, Spontaneous; Thioguanine | 1977 |
Chemotherapy for adult acute nonlymphocytic leukemia with daunorubicin and cytosine arabinoside.
Topics: Acute Disease; Adolescent; Adult; Aged; Central Nervous System Diseases; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Meningeal Neoplasms; Middle Aged; Neoplasm Metastasis; Remission, Spontaneous; Time Factors | 1977 |
Clinical studies of beta-thioguanine deoxyriboside alone and in combination with arabinosyl cytosine.
Topics: Acute Disease; Adolescent; Adult; Aged; Child; Child, Preschool; Cytarabine; Deoxyguanosine; Deoxyribonucleosides; Drug Therapy, Combination; Female; Guanosine; Humans; Leukemia; Leukopenia; Male; Middle Aged; Neoplasm Metastasis; Neoplasms; Remission, Spontaneous; Thioguanine; Thionucleosides; Thrombocytopenia; Time Factors | 1976 |
Maintenance of remission in adult acute nonlymphoblastic leukemia using intermittent courses of cytosine arabinoside (NSC-63878) and 6-thioguanine (NSC-752).
Topics: Acute Disease; Adolescent; Adult; Aged; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Middle Aged; Remission, Spontaneous; Thioguanine | 1976 |
The effect of cytosine arabinoside on platelet aggregation.
Topics: Acute Disease; Cytarabine; Humans; In Vitro Techniques; Leukemia; Platelet Aggregation; Remission, Spontaneous | 1976 |
Occurrence of hepatitis and hepatitis B surface antigen in adult patients with acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Blood Transfusion; Cyclophosphamide; Cytarabine; Female; Follow-Up Studies; Hepatitis; Hepatitis B Antigens; Humans; Immunoelectrophoresis; Leukemia; Leukemia, Lymphoid; Male; Middle Aged; Nitrosourea Compounds; Radioimmunoassay; Remission, Spontaneous; Statistics as Topic; Vincristine | 1975 |
[In vitro study of sensitivity of leukemic cells to cytotoxic drugs (anticytogram)].
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Agents; Asparaginase; Carbon Radioisotopes; Cells, Cultured; Cyclophosphamide; Cytarabine; Daunorubicin; Depression, Chemical; Humans; In Vitro Techniques; Leukemia; Leukemia, Lymphoid; Mercaptopurine; Middle Aged; Monomethylhydrazine; Prednisolone; Remission, Spontaneous; Thymidine; Tritium; Uridine; Vincristine | 1975 |
Drugs five years later: cytarabine.
Topics: Acute Disease; Adult; Animals; Bone Marrow Diseases; Central Nervous System Diseases; Cyclophosphamide; Cytarabine; Daunorubicin; DNA, Neoplasm; Drug Therapy, Combination; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma; Prednisone; Remission, Spontaneous; Thioguanine; Vincristine; Virus Diseases | 1975 |
Acute leukemia in adults: assessment of remission induction with combination chemotherapy by clinical and cell-culture criteria.
Topics: Acute Disease; Adolescent; Adult; Aged; Bone Marrow; Bone Marrow Cells; Cell Division; Cells, Cultured; Clone Cells; Culture Media; Cyclophosphamide; Cytarabine; Drug Administration Schedule; Drug Therapy, Combination; Female; Granulocytes; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Remission, Spontaneous; Vincristine | 1975 |
[Leukemic meningo-encephalopathy. Clinical and therapeutic considerations].
Topics: Acute Disease; Asparaginase; Child; Child, Preschool; Cobalt Isotopes; Cytarabine; Humans; Leukemia, Lymphoid; Meningoencephalitis; Methotrexate; Radioisotope Teletherapy | 1975 |
[Results of combined chemotherapy in treatment-resistant leukaemia of adults (author's transl)].
Topics: Acute Disease; Adolescent; Adult; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia; Leukemia, Myeloid, Acute; Methotrexate; Middle Aged; Prednisone; Remission, Spontaneous; Thioguanine; Time Factors; Vincristine | 1975 |
Veno-occlusive disease of the liver after chemotherapy of acute leukemia. Report of two cases.
Topics: Acute Disease; Adolescent; Aged; Budd-Chiari Syndrome; Chemical and Drug Induced Liver Injury; Cytarabine; Hepatic Veins; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Liver; Male; Thioguanine | 1976 |
Treatment of adult acute non-lymphocytic leukemia.
Topics: Acute Disease; Adolescent; Adult; Cytarabine; Humans; Leukemia; Middle Aged; Remission, Spontaneous; Thioguanine | 1975 |
Growth kinetics of solid tumors. Implications for chemotherapy.
Topics: Acute Disease; Adenocarcinoma; Animals; Antineoplastic Agents; Cell Division; Colonic Neoplasms; Culture Techniques; Cytarabine; DNA; Humans; Kinetics; Leukemia; Meiosis; Melanoma; Mitosis; Neoplasms; Neoplasms, Experimental; Rats; Thymidine; Tritium; Vinblastine | 1975 |
Chemotherapy of the transplantable acute leukemia L5222 in rats.
Topics: Acute Disease; Animals; Antineoplastic Agents; Asparaginase; Carmustine; Cell Division; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Hydrazones; Leukemia, Experimental; Male; Mercaptopurine; Neoplasm Transplantation; Prednisolone; Rats; Transplantation, Homologous; Vincristine | 1975 |
[Models of polychemotherapy in acute leukemias].
Topics: Acute Disease; Antineoplastic Agents; Asparaginase; Carmustine; Cyclophosphamide; Cytarabine; Dacarbazine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia; Mercaptopurine; Thioguanine | 1975 |
[Cytosine arabinoside in the treatment of acute leukemia in children].
Topics: Acute Disease; Age Factors; Child; Cytarabine; Drug Evaluation; Humans; Leukemia | 1975 |
Ph1-positive megakaryoblastic leukemia.
Topics: Acute Disease; Autoradiography; Blood Cell Count; Blood Platelets; Bone Marrow; Carmustine; Chromosome Aberrations; Chromosomes, Human, 16-18; Chromosomes, Human, 19-20; Chromosomes, Human, 21-22 and Y; Chromosomes, Human, 6-12 and X; Cytarabine; Female; Humans; Lymph Nodes; Megakaryocytes; Middle Aged; Mitosis; Pneumonia; Thioguanine; Thrombocythemia, Essential; Vincristine | 1975 |
[New quadruple combination intermittent therapy (cyclocytidine, adriamycin, 6MP and prednisolone: CyAMP) for adult acute leukemia (author's transl)].
Topics: Acute Disease; Adult; Aged; Cytarabine; Doxorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Mercaptopurine; Middle Aged; Prednisolone | 1975 |
[Cell cycle effect of cytosine arabinoside, vincristine, and massive leukapheresis on human leukemic blasts and its application to a quadruple combination chemotherapy of acute leukemia (author's transl)].
Topics: Acute Disease; Adult; Blood Transfusion; Bone Marrow; Bone Marrow Cells; Cytarabine; DNA, Neoplasm; Drug Therapy, Combination; Female; Humans; Leukemia; Leukocytes; Male; Mitosis; Vincristine | 1975 |
[A new quadruple combination chemotherapy (Neo-DCMP) in acute leukemia (author's transl)].
Topics: Acute Disease; Adult; Child; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia; Mercaptopurine; Middle Aged; Prednisolone | 1975 |
[Quadruple combination chemotherapy of acute leukemia using daunomycin, cytosine arabinoside, vincristine and prednisolone (author's transl)].
Topics: Acute Disease; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia; Prednisolone; Vincristine | 1975 |
[Diagnosis and therapy of neoplastic meningosis].
Topics: Acute Disease; Central Nervous System Diseases; Cytarabine; Humans; Injections, Spinal; Leukemia; Meninges; Methotrexate; Mitolactol; Neoplasm Metastasis; Nitrosourea Compounds; Pyrimethamine; Radiotherapy | 1975 |
The role of cytosine arabinoside maintenance in acute nonlymphoblastic leukemia.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Bone Marrow Diseases; Child; Cytarabine; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Leukemia; Middle Aged; Muramidase; Prednisone; Vincristine | 1975 |
Letter: Treatment of acute leukaemia.
Topics: Acute Disease; Cytarabine; Doxorubicin; Drug Therapy, Combination; Humans; Leukemia; Methotrexate; Podophyllotoxin | 1975 |
[Method of administration and inactivation of cytosine arabinoside in acute leukemia].
Topics: Acute Disease; Cytarabine; Humans; Leukemia | 1975 |
[Treatment of central nervous system leukemia in acute childhood leukemia. I. Results of intrathecal single or multiple drug combination therapy (author's transl)].
Topics: Acute Disease; Central Nervous System Diseases; Child; Child, Preschool; Cytarabine; Drug Therapy, Combination; Female; Humans; Hydrocortisone; Infant; Injections, Spinal; Leukemia; Male; Methotrexate | 1975 |
Feasibility of using quinine, a potential multidrug resistance-reversing agent, in combination with mitoxantrone and cytarabine for the treatment of acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytarabine; Drug Resistance; Feasibility Studies; Female; Humans; Leukemia; Male; Membrane Glycoproteins; Middle Aged; Mitoxantrone; Neoplasm Proteins; Quinine; Treatment Outcome | 1992 |
Acute myeloid leukaemia with an unusual phenotype: myeloperoxidase (+), CD13 (-), CD14 (-) and CD33 (-).
Topics: Acid Phosphatase; Acute Disease; Alkaline Phosphatase; Antigens, CD; Antigens, Differentiation, Myelomonocytic; CD13 Antigens; Cytarabine; Drug Therapy, Combination; Flow Cytometry; Humans; Immunohistochemistry; Immunophenotyping; Leukemia, Myeloid; Lipopolysaccharide Receptors; Mitoxantrone; Peroxidase; Phenotype; Sialic Acid Binding Ig-like Lectin 3 | 1992 |
[Treatment of leukemia: discussion].
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Granulocyte Colony-Stimulating Factor; Hematologic Tests; Humans; L-Lactate Dehydrogenase; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mercaptopurine; Prednisolone; Remission Induction | 1992 |
Acute bilateral parotitis during chemotherapy for acute lymphoblastic leukemia.
Topics: Acute Disease; Adult; Ancitabine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Male; Parotitis; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1992 |
Acute myeloid leukemia (AML) in Down's syndrome is highly responsive to chemotherapy: experience on Pediatric Oncology Group AML Study 8498.
Topics: Acute Disease; Adolescent; Adult; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Azacitidine; Child; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Daunorubicin; Down Syndrome; Etoposide; Female; Follow-Up Studies; Humans; Leukemia, Myeloid; Male; Mercaptopurine; Methotrexate; Prednisone; Remission Induction; Thioguanine; Vincristine | 1992 |
A comparison of the lethal effects in culture of cytosine arabinoside and arabinofuranosyl-5-azacytosine acting on the blast cells fo acute myeloblastic leukemia.
Topics: Acute Disease; Antineoplastic Agents; Azacitidine; Blast Crisis; Cell Survival; Cytarabine; Humans; Leukemia, Myeloid; Tumor Cells, Cultured | 1992 |
Comparative effects of G-CSF, GM-CSF and IL-3 on cytosine arabinoside- and daunorubicin-mediated cytotoxicity of acute myeloid leukemia cells and normal myeloid progenitors.
Topics: Acute Disease; Cell Survival; Colony-Stimulating Factors; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid; Reference Values; Stem Cells; Tumor Cells, Cultured | 1992 |
DAE (daunorubicin, Ara-C, and etoposide) and intermediate dose Ara-C for remission induction and consolidation treatment of adult patients with acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Remission Induction; Survival Analysis | 1992 |
Differences in the intracellular pharmacokinetics of cytosine arabinoside (AraC) between circulating leukemic blasts and normal mononuclear blood cells.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Arabinofuranosyluracil; Cytarabine; Daunorubicin; Drug Administration Schedule; Humans; Leukemia, Myeloid; Leukocytes, Mononuclear; Lymphoma, Non-Hodgkin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Thioguanine | 1992 |
Non-aggressive therapy for chronic myeloid leukaemia in blastic transformation.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Child; Cytarabine; Daunorubicin; Doxorubicin; Female; Humans; Hydroxyurea; Leukemia; Leukemia, Myeloid, Chronic-Phase; Male; Methotrexate; Middle Aged; Remission Induction; Thioguanine; Vincristine | 1992 |
Acute lysis pneumopathy after chemotherapy for acute myelomonocytic leukemia with abnormal marrow eosinophils.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cough; Cytarabine; Daunorubicin; Eosinophils; Female; Humans; Hypoxia; Leukemia, Myelomonocytic, Acute; Respiratory Insufficiency; Tumor Lysis Syndrome | 1992 |
Granulocyte-macrophage colony-stimulating factor and interleukin-3 enhance the incorporation of cytosine arabinoside into the DNA of leukemic blasts and the cytotoxic effect on clonogenic cells from patients with acute myeloid leukemia.
Topics: Acute Disease; Arabinofuranosylcytosine Triphosphate; Blast Crisis; Cytarabine; DNA, Neoplasm; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-3; Leukemia, Myeloid; S Phase; Tumor Stem Cell Assay | 1992 |
Enhancement of the cytotoxicity of cytosine arabinoside by interleukin-3.
Topics: Acute Disease; Arabinofuranosylcytosine Triphosphate; Blast Crisis; Cytarabine; Drug Synergism; Feasibility Studies; Humans; Interleukin-1; Interleukin-3; Leukemia, Myeloid; Tumor Stem Cell Assay | 1992 |
Gingival status during chemical plaque control with or without prior mechanical plaque removal in patients with acute myeloid leukaemia.
Topics: Aclarubicin; Acute Disease; Adolescent; Aged; Antineoplastic Combined Chemotherapy Protocols; Bacterial Infections; Chlorhexidine; Cytarabine; Dental Calculus; Dental Plaque; Dental Scaling; Female; Gingival Hemorrhage; Gingivitis; Humans; Leukemia, Myeloid; Leukopenia; Male; Middle Aged; Mouthwashes; Netilmicin; Piperacillin; Premedication; Thrombocytopenia | 1992 |
Is allogeneic bone marrow transplantation the best treatment for young adult patients with acute myeloid leukemia in first complete remission. The BGMT Group.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Drug Administration Schedule; Evaluation Studies as Topic; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Prospective Studies; Recurrence; Remission Induction; Transplantation, Homologous | 1992 |
[Mitoxantrone and conventional-dose cytosine arabinoside for relapsed and refractory acute leukemia].
Topics: Acute Disease; Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Female; Humans; Leukemia; Male; Middle Aged; Mitoxantrone; Remission Induction | 1992 |
Mitozantrone and cytosine arabinoside as first line therapy in elderly patients with acute myeloid leukaemia. Trent Working Party on Adult Leukaemia.
Topics: Acute Disease; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Leukemia, Myeloid; Mitoxantrone | 1992 |
Successful treatment with low dose Ara-C in de novo acute myeloid leukemia with trilineage myelodysplasia.
Topics: Acute Disease; Aged; Cytarabine; Female; Humans; Leukemia, Myeloid; Myelodysplastic Syndromes | 1992 |
Intracellular cytosine arabinoside accumulation and cytosine arabinoside triphosphate formation in leukemic blast cells is inhibited by etoposide and teniposide.
Topics: Acute Disease; Adult; Aged; Amsacrine; Arabinofuranosylcytosine Triphosphate; Cytarabine; Drug Interactions; Etoposide; Humans; Leukemia; Middle Aged; Neoplastic Stem Cells; Phosphorylation; Teniposide; Tumor Cells, Cultured | 1992 |
Pathways of viral gene expression during acute neuronal infection with HSV-1.
Topics: Acute Disease; Acyclovir; Animals; Antigens, Viral; beta-Galactosidase; Cytarabine; DNA, Viral; Female; Ganglia, Spinal; Herpes Simplex; Mice; Neurons; Phenotype; Recombinant Proteins; Tissue Distribution; Virus Replication | 1992 |
The combination of quercetin and cytosine arabinoside synergistically inhibits leukemic cell growth.
Topics: Acute Disease; Cell Division; Cytarabine; Drug Synergism; Humans; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Quercetin; Receptors, Estrogen; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1992 |
Concomitant chronic lymphocytic leukemia (CLL) and acute myeloid leukemia. Complete remission of CLL achieved with high-dose cytosine arabinoside.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, B-Cell; Leukemia, Myeloid; Middle Aged; Neoplasms, Multiple Primary; Remission Induction | 1992 |
[p170 in multiple myeloma and acute leukemia].
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biomarkers, Tumor; Colonic Neoplasms; Cytarabine; Daunorubicin; Drug Resistance; Female; Gene Expression Regulation, Neoplastic; Humans; Leukemia; Male; Melphalan; Membrane Glycoproteins; Middle Aged; Multiple Myeloma; Neoplasm Proteins; Neoplastic Stem Cells; Peptichemio; Plasma Cells; Prednisone; Remission Induction; Survival Rate; Tumor Cells, Cultured; Vincristine | 1991 |
[Kinetics of circulating hematopoietic stem cells following chemotherapy in patients with hematopoietic malignancies].
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cell Cycle; Colony-Stimulating Factors; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cells; Humans; Leukemia; Lymphoma, Non-Hodgkin; Male; Mercaptopurine; Middle Aged; Multiple Myeloma; Prednisolone; Prednisone; Vincristine | 1990 |
Mitozantrone and cytosine arabinoside as first-line therapy in elderly patients with acute myeloid leukaemia.
Topics: Acute Disease; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Prognosis; Prospective Studies; Remission Induction | 1991 |
Intensive individualized induction therapy with behenoyl cytarabine, daunorubicin and 6-mercaptopurine followed by intensive consolidation including intermediate-dose continuous cytarabine, mitoxantron, etoposide and vinca alkaloids in acute myeloid leuke
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myeloid; Male; Mercaptopurine; Mitoxantrone; Vinca Alkaloids | 1991 |
Remission of hypoplastic acute leukemia by low dose Ara-C: one case report.
Topics: Acute Disease; Aged; Cytarabine; Female; Humans; Leukemia; Remission Induction | 1991 |
[Controversies in the treatment of acute myeloid leukemia of the adult. Chemotherapy vs bone marrow transplantation].
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid; Middle Aged | 1991 |
Treatment with interleukin-3 plus granulocyte-macrophage colony-stimulating factors improves the selectivity of Ara-C in vitro against acute myeloid leukemia blasts.
Topics: Acute Disease; Arabinofuranosylcytosine Triphosphate; Blast Crisis; Bone Marrow Cells; Cells, Cultured; Colony-Forming Units Assay; Cytarabine; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-3; Kinetics; Leukemia, Myeloid; Monocytes; Recombinant Proteins; Reference Values; Stem Cells; Tumor Cells, Cultured | 1991 |
Low-dose cytarabine for acute myeloid leukaemia and myelodysplastic syndromes: in vivo and in vitro cytotoxicity.
Topics: Acute Disease; Aged; Aged, 80 and over; Cell Division; Cell Survival; Cytarabine; Female; Granulocytes; Humans; Leukemia, Myeloid; Leukocyte Count; Male; Middle Aged; Myelodysplastic Syndromes | 1991 |
Recombinant human granulocyte-macrophage colony-stimulating factor after chemotherapy in patients with acute myeloid leukemia at higher age or after relapse.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Neutropenia; Recombinant Proteins; Remission Induction; Thioguanine | 1991 |
High-dose ara-C and etoposide in refractory or relapsing acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Evaluation; Etoposide; Female; Humans; Leukemia; Male; Middle Aged; Recurrence; Time Factors | 1991 |
Post consolidation therapy for adult patients with acute myeloid leukaemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Combined Modality Therapy; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Remission Induction; Thioguanine; Time Factors | 1991 |
Dysmegakaryopoiesis resembling acute megakaryoblastic leukemia in treated acute myeloid leukemia.
Topics: Acute Disease; Antigens, CD; Bone Marrow; Cytarabine; Daunorubicin; Diagnosis, Differential; Doxorubicin; Etoposide; Humans; Hyperplasia; Immunophenotyping; Leukemia, Megakaryoblastic, Acute; Leukemia, Myeloid; Megakaryocytes; Mitoxantrone; Myelodysplastic Syndromes; Prognosis; Time Factors | 1991 |
Salvage chemotherapy containing moderate-dose cytosine arabinoside and mitoxantrone for relapsed and resistant acute myeloid leukaemia.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Resistance; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Recurrence; Remission Induction | 1991 |
Acute tumor lysis syndrome in a patient with chronic myelogenous leukemia in blast crisis: role of high-dose Ara-C.
Topics: Acute Disease; Adult; Blast Crisis; Bone Marrow Transplantation; Cytarabine; Dose-Response Relationship, Drug; Graft vs Host Disease; Humans; Kidney Diseases; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Tumor Lysis Syndrome | 1990 |
[Beta-thromboglobulin and platelet factor 4 in a follow-up of acute myelofibrosis (megakaryoblastic leukemia)].
Topics: Acute Disease; Aged; beta-Thromboglobulin; Cytarabine; Female; Follow-Up Studies; Humans; Leukemia, Megakaryoblastic, Acute; Platelet Factor 4; Primary Myelofibrosis; Time Factors | 1990 |
[Comparison among three preconditioning regimens for allogeneic bone marrow transplantation in hematological malignancies].
Topics: Acute Disease; Bone Marrow Transplantation; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Humans; Leukemia; Remission Induction; Retrospective Studies; Risk; Survival Rate; Whole-Body Irradiation | 1990 |
[Two cases of bi-phenotypic type hybrid acute leukemia with 8;21 translocation].
Topics: Aclarubicin; Acute Disease; Aged; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Cytarabine; Female; Humans; Leukemia; Phenotype; Translocation, Genetic | 1990 |
[A case of complete remission from acute unclassified leukemia achieved by using a prodrug of ara C, stearyl-ara-CMP (YNK01)].
Topics: Acute Disease; Administration, Oral; Antineoplastic Agents; Arabinonucleotides; Cytarabine; Cytidine Monophosphate; Drug Administration Schedule; Female; Humans; Leukemia; Middle Aged; Prodrugs; Remission Induction | 1990 |
Fatal pulmonary failure complicating high-dose cytosine arabinoside therapy in acute leukemia.
Topics: Acute Disease; Adult; Aged; Cytarabine; Drug Administration Schedule; Female; Humans; Intestinal Mucosa; Leukemia; Lung; Male; Middle Aged; Myocardium; Respiratory Distress Syndrome; Respiratory Insufficiency | 1990 |
Continuous intravenous administration of daunorubicin and cytarabine for remission induction of poor risk acute myelogenous leukaemias and myelodysplastic syndromes.
Topics: Acute Disease; Adult; Aged; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Middle Aged; Myelodysplastic Syndromes; Recurrence; Remission Induction; Time Factors | 1990 |
Magnetic resonance imaging follow-up in patients with acute leukemia during induction chemotherapy.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Daunorubicin; Humans; Leukemia; Magnetic Resonance Imaging; Middle Aged; Mitoxantrone; Remission Induction; Thioguanine | 1990 |
Treatment of relapsed or refractory acute leukemia: comparison of two different regimens.
Topics: Acute Disease; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Combined Modality Therapy; Cytarabine; Etoposide; Humans; Leukemia; Mitoxantrone; Neoplasm Recurrence, Local | 1990 |
Aggressive polychemotherapy for acute myelofibrosis.
Topics: Acute Disease; Adult; Aged; Bone Marrow; Cytarabine; Daunorubicin; Drug Therapy, Combination; Erythrocyte Count; Female; Humans; Infusions, Intravenous; Injections, Intravenous; Male; Megakaryocytes; Middle Aged; Primary Myelofibrosis; Thioguanine | 1990 |
Saturation of intracellular cytosine arabinoside triphosphate accumulation in human leukemic blast cells.
Topics: Acute Disease; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Binding Sites; Biological Transport; Cell Membrane; Cytarabine; Deoxycytidine Kinase; Extracellular Space; Humans; Leukemia; Lymphocytes; Nucleosides; Phosphorylation; Thioinosine; Tumor Cells, Cultured | 1990 |
Fractional administration of adriblastin and modified route of ara-C administration for the treatment of acute leukaemia.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Doxorubicin; Humans; Leukemia; Middle Aged | 1985 |
3-Deazauridine (NSC 126849): an interesting modulator of biochemical response.
Topics: 3-Deazauridine; Acute Disease; Animals; Antineoplastic Agents; Azacitidine; Cytarabine; Decitabine; Drug Evaluation; Drug Synergism; Galactosamine; Humans; Kinetics; Leukemia; Neoplasms; Thymidine; Uridine | 1986 |
[Treatment of acute leukemia with "MB-triple V" therapy--a comparative study of "MB-triple V" therapy and B-triple V therapy].
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Evaluation; Etoposide; Female; Humans; Leukemia; Leukocyte Count; Male; Middle Aged; Mitoxantrone; Remission Induction; Vinblastine; Vincristine; Vindesine | 1989 |
Central nervous system involvement in haematological malignancies.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Therapy; Cytarabine; Humans; Injections, Spinal; Leukemia; Lymphoma; Meningeal Neoplasms; Methotrexate; Remission Induction; Spinal Neoplasms | 1989 |
Bone marrow transplantation for children with myelodysplastic syndromes.
Topics: Acute Disease; Adolescent; Adult; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Female; Graft Survival; Graft vs Host Disease; Humans; Male; Myelodysplastic Syndromes | 1989 |
[High doses of ARA C in the treatment of acute leukemia].
Topics: Acute Disease; Adolescent; Adult; Child, Preschool; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged | 1989 |
Respiratory insufficiency in acute leukemia following treatment with cytosine arabinoside and septicemia with streptococcus viridans.
Topics: Acute Disease; Adult; Cytarabine; Female; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Respiratory Insufficiency; Sepsis; Streptococcal Infections | 1989 |
Intrathecal cytosine arabinoside-induced acute, rapidly reversible paralysis.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Cytarabine; Humans; Injections, Spinal; Male; Middle Aged; Paraplegia | 1989 |
Experience with combinations containing mitoxantrone in the treatment of adult acute leukemias.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged; Mitoxantrone; Vincristine | 1989 |
Combined medical and psychological treatment of postchemotherapy nausea and vomiting: a case study.
Topics: Acute Disease; Behavior Therapy; Combined Modality Therapy; Cytarabine; Diazepam; Flurazepam; Humans; Leukemia; Male; Middle Aged; Nausea; Vomiting | 1989 |
[Effects of low dose Ara-C regimen in acute leukemias and RAEB].
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Anemia, Refractory, with Excess of Blasts; Cytarabine; Drug Evaluation; Female; Humans; Leukemia; Male; Middle Aged; Remission Induction | 1989 |
Acute leukaemia during pregnancy.
Topics: Acute Disease; Adult; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Female; Humans; Infant, Newborn; Labor, Induced; Leukemia; Pregnancy; Pregnancy Complications, Neoplastic; Thioguanine | 1988 |
[New combination chemotherapy of adult acute nonlymphocytic leukemia].
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Leukemia; Male; Methotrexate; Middle Aged; Prednisolone; Vincristine; Zinostatin | 1985 |
Combination therapy with aclacinomycin in acute leukemia.
Topics: Aclarubicin; Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Leukemia; Naphthacenes; Thioguanine | 1986 |
Peripheral neuropathy after high-dose cytosine arabinoside, daunorubicin, and asparaginase consolidation for acute nonlymphocytic leukemia.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Peripheral Nervous System Diseases | 1986 |
Low-dose cytarabine in myelodysplastic syndromes and acute leukemia. A comment.
Topics: Acute Disease; Cytarabine; Hematopoietic Stem Cells; Humans; Leukemia; Myelodysplastic Syndromes | 1986 |
[Aclarubicin-related pancreatitis in a child with AML].
Topics: Aclarubicin; Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Naphthacenes; Pancreatitis; Vincristine | 1988 |
In vitro short-term sensitivity test for the prediction of response to chemotherapy in acute non-lymphocytic leukemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cells, Cultured; Cytarabine; Daunorubicin; Drug Screening Assays, Antitumor; Female; Humans; Leukemia; Male; Middle Aged; Time Factors; Uridine | 1988 |
["A-Triple-V" treatment of relapsed or refractory acute leukemia].
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Evaluation; Etoposide; Female; Humans; Leukemia; Male; Middle Aged; Pilot Projects; Remission Induction; Vinblastine; Vincristine | 1988 |
[Acute graft-versus-host disease in a patient with acute myeloblastic leukemia following consolidation therapy and platelet transfusions].
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Daunorubicin; Female; Graft vs Host Disease; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Platelet Transfusion; Prednisolone; Transfusion Reaction | 1988 |
Combined chemotherapy with m-amsacrine in high-risk patients with acute non-lymphocytic leukemia.
Topics: Acute Disease; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Follow-Up Studies; Humans; Leukemia; Middle Aged; Thioguanine | 1987 |
High-dose ara-C and VP-16 before conditioning for bone marrow transplantation in patients with high-risk leukemia.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Cytarabine; Etoposide; Female; Humans; Leukemia; Male | 1987 |
Proto-oncogene transcript levels and acute nonlymphocytic leukemia.
Topics: Acute Disease; Blast Crisis; Bone Marrow; Cell Differentiation; Cell Division; Cytarabine; Gene Expression Regulation; Histones; Humans; Leukemia; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogenes; RNA, Neoplasm; Triose-Phosphate Isomerase | 1987 |
Prolonged survival after high-dose cytosine arabinoside and amsacrine induction in patients with previously untreated de novo acute nonlymphocytic leukemia.
Topics: Acute Disease; Amsacrine; Bone Marrow Transplantation; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia; Prognosis | 1987 |
Sequential pilot studies of intensive postremission chemotherapy for acute nonlymphocytic leukemia.
Topics: Acute Disease; Adolescent; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmustine; Combined Modality Therapy; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia; Male; Middle Aged; Mitoxantrone; Pilot Projects; Thioguanine | 1987 |
VP-16-based regimen in adult acute nonlymphoblastic leukemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Erythropoiesis; Etoposide; Hematopoietic Stem Cells; Humans; Leukemia; Thioguanine; Vincristine | 1988 |
Chemotherapy for relapsed and resistant acute nonlymphoblastic leukemia. Effect of ATA, an amsacrine-containing regime.
Topics: Acute Disease; Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Resistance; Female; Humans; Leukemia; Male; Middle Aged; Recurrence; Thioguanine | 1988 |
Non-cardiogenic pulmonary edema complicating intermediate and high-dose Ara C treatment for relapsed acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged; Pulmonary Edema; Radiography, Thoracic; Recurrence; Retrospective Studies | 1988 |
Therapeutic effects of low-dose cytosine arabinoside, alpha-interferon, 1 alpha-hydroxyvitamin D3 and retinoic acid in acute leukemia and myelodysplastic syndromes.
Topics: Actuarial Analysis; Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Female; Humans; Hydroxycholecalciferols; Interferon Type I; Leukemia; Male; Middle Aged; Myelodysplastic Syndromes; Remission Induction; Tretinoin | 1988 |
Mitoxantrone.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cytarabine; Daunorubicin; DNA; Drug Administration Schedule; Humans; Leukemia; Mitoxantrone | 1988 |
[A therapeutic trial with low-dose Ara-C in acute nonlymphocytic leukemia and myelodysplastic syndromes: a study of 15 cases].
Topics: Acute Disease; Adult; Aged; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged; Myelodysplastic Syndromes | 1988 |
Recurrent fungal pneumonias in patients with acute nonlymphocytic leukemia undergoing multiple courses of intensive chemotherapy.
Topics: Acute Disease; Adult; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Doxorubicin; Female; Humans; Leukemia; Lung Diseases, Fungal; Male; Pneumonia; Recurrence; Remission Induction; Risk Factors | 1988 |
[Treatment of childhood acute non-lymphocytic leukemia with the AVC regimen (adriamycin, vincristine and cytosine arabinoside)].
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Administration Schedule; Female; Humans; Infant; Leukemia; Leukocyte Count; Male; Vincristine | 1987 |
[Effectiveness of low dose Ara-C in acute nonlymphocytic leukemia and myelodysplastic syndromes--analysis of factors influencing the duration of responses, survival and clinical effects].
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged; Myelodysplastic Syndromes; Remission Induction | 1987 |
[The effect of N4-behenoyl-1-beta-D-arabinofuranosylcytosine on human erythrocytes].
Topics: Acute Disease; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood Sedimentation; Cytarabine; Erythrocytes; Humans; Leukemia; Osmotic Fragility | 1987 |
["B-triple V" therapy as a initial induction treatment of acute leukemias].
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Humans; Leukemia; Male; Middle Aged; Remission Induction; Vinblastine; Vincristine | 1987 |
Ocular toxicity of low dose cytosar.
Topics: Acute Disease; Cytarabine; Eye; Humans; Leukemia | 1987 |
[Low-dose cytosine arabinoside therapy in relapsed acute leukemia: correlation of clinical response and in vitro sensitivity tests].
Topics: Acute Disease; Adolescent; Adult; Age Factors; Child; Cytarabine; Drug Screening Assays, Antitumor; Female; Humans; Leukemia; Male; Recurrence; Tumor Cells, Cultured | 1987 |
Aclacinomycin A and behenoyl arabinofuranosylcytosine combination chemotherapy for previously untreated acute leukemia.
Topics: Aclarubicin; Actuarial Analysis; Acute Disease; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Child; Child, Preschool; Cytarabine; Humans; Leukemia; Middle Aged; Naphthacenes | 1986 |
Progressive ascending paralysis following administration of intrathecal and intravenous cytosine arabinoside. A Pediatric Oncology Group study.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain; Cytarabine; Female; Humans; Injections, Intravenous; Injections, Spinal; Leukemia, Myeloid, Acute; Lung; Muscles; Paralysis; Spinal Cord; Time Factors | 1986 |
Neurotoxicity associated with systemic high-dose cytosine arabinoside.
Topics: Acute Disease; Adolescent; Adult; Aged; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Nervous System Diseases | 1986 |
Dose-related pharmacologic effects of high dose ara-C and its use in combination with asparaginase for the treatment of patients with acute non-lymphocytic leukemia.
Topics: Acute Disease; Animals; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Carcinoma, Ehrlich Tumor; Cell Line; Cytarabine; Dose-Response Relationship, Drug; Drug Resistance; Humans; Leukemia; Leukemia L5178; Mice | 1986 |
Cellular pharmacology and optimal therapeutic concentrations of 1-beta-D-arabinofuranosylcytosine 5'-triphosphate in leukemic blasts during treatment of refractory leukemia with high-dose 1-beta-D-arabinofuranosylcytosine.
Topics: Acute Disease; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Biotransformation; Chromatography, High Pressure Liquid; Cytarabine; Humans; Kinetics; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute | 1986 |
A phase I-II study of cytosine arabinoside, daunorubicin, and VP16-213 in adult patients with acute non-lymphocytic leukemia.
Topics: Acute Disease; Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Evaluation; Etoposide; Female; Humans; Leukemia; Male; Middle Aged; Nausea; Stomatitis; Vomiting | 1986 |
Treatment of refractory acute lymphoblastic leukemia with teniposide and cytarabine.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Child; Child, Preschool; Cytarabine; Humans; Leukemia, Lymphoid; Methotrexate; Teniposide | 1986 |
Prediction of response of patients with acute nonlymphocytic leukaemia to remission induction therapy: use of clinical measurements.
Topics: Acute Disease; Age Factors; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Humans; Leukemia; Middle Aged; Naphthacenes; Prognosis; Retrospective Studies; Time Factors | 1986 |
Systemic high-dose ara-C for the treatment of meningeal leukemia in adult acute lymphoblastic leukemia and non-Hodgkin's lymphoma.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Cytarabine; Drug Administration Schedule; Female; Humans; Leukemia, Lymphoid; Lymphoma; Male; Meningeal Neoplasms; Methotrexate; Middle Aged | 1986 |
[Mucosal injury of aclacinomycin A in patients with adult acute leukemia--comparison of BH-AC. AMP therapy and BH-AC. DMP therapy].
Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Hemorrhage; Humans; Leukemia; Male; Mercaptopurine; Middle Aged; Mucous Membrane; Naphthacenes; Prednisolone; Urinary Bladder Diseases | 1986 |
Pharmacology and toxicity of high-dose cytarabine by 72-hour continuous infusion.
Topics: Acute Disease; Cytarabine; Dose-Response Relationship, Drug; Drug Evaluation; Humans; Infusions, Parenteral; Kinetics; Leukemia; Leukemia, Lymphoid | 1986 |
Oral idarubicin in combination with cytosine-arabinoside in previously untreated patients with acute non-lymphocytic leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Daunorubicin; Female; Humans; Idarubicin; Leukemia; Male; Middle Aged | 1986 |
Teniposide and cytarabine combination chemotherapy in the treatment of relapsed adolescent and adult acute lymphoblastic leukemia.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Hematologic Diseases; Humans; Leukemia, Lymphoid; Male; Nervous System Neoplasms; Teniposide | 1986 |
Behenoyl cytosine arabinoside, daunorubicin, 6-mercaptopurine, and prednisolone combination therapy for acute myelogenous leukemia in adults and prognostic factors related to remission duration and survival length.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisone; Prognosis; Statistics as Topic | 1986 |
High-dose cytosine arabinoside with amsacrine for treatment of acute lymphoblastic leukemia.
Topics: Acute Disease; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Leukemia, Lymphoid; Nervous System Neoplasms | 1986 |
Acute meningitis and cerebellar dysfunction complicating high-dose cytosine arabinoside therapy.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Diseases; Cytarabine; Female; Humans; Leukemia, Lymphoid; Meningitis; Meningitis, Aseptic | 1986 |
A phase II study of high-dose cytosine arabinoside in the treatment of acute leukaemia in adults.
Topics: Acute Disease; Adult; Aged; Blast Crisis; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Middle Aged; Time Factors | 1987 |
Daunorubicin versus aclarubicin in combination with cytarabine and thioguanine in elderly patients with acute nonlymphocytic leukemia, a preliminary report.
Topics: Aclarubicin; Acute Disease; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia; Male; Middle Aged; Naphthacenes; Thioguanine | 1987 |
Idarubicin in sequential combination with cytosine arabinoside in the treatment of relapsed and refractory patients with acute non-lymphoblastic leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Idarubicin; Leukemia; Male; Middle Aged | 1987 |
Idarubicin in combination with etoposide and cytarabine in adult untreated acute non lymphoblastic leukemia.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Idarubicin; Leukemia; Male; Middle Aged | 1987 |
Few genetic mutations, many cancers, say experts.
Topics: Acute Disease; Child; Cytarabine; Eye Neoplasms; Humans; Leukemia, Myeloid, Acute; Mutation; Neoplasms; Oncogenes; Retinoblastoma; T-Lymphocytes, Cytotoxic | 1986 |
Results of treatment of advanced-stage Burkitt's lymphoma and B cell (SIg+) acute lymphoblastic leukemia with high-dose fractionated cyclophosphamide and coordinated high-dose methotrexate and cytarabine.
Topics: Actuarial Analysis; Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; B-Lymphocytes; Burkitt Lymphoma; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Leukemia, Lymphoid; Male; Methotrexate; Neoplasm Staging | 1986 |
Cerebrospinal fluid beta-2-microglobulin: a reliable index of leukaemic infiltration of central nervous system.
Topics: Acute Disease; Adolescent; Adult; Aged; beta 2-Microglobulin; Central Nervous System Diseases; Child; Cytarabine; Female; Follow-Up Studies; Humans; Injections, Spinal; Leukemia; Male; Methotrexate; Middle Aged | 1986 |
[Intensive polychemotherapy in the treatment of acute non-lymphoblastic leukemia: comparison of the prospective protocols DATOP/79 and DATOP/82].
Topics: Actuarial Analysis; Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia; Male; Middle Aged; Prednisone; Thioguanine; Vincristine | 1987 |
[The clinical effect of low-dose Ara-C in patients with refractory acute nonlymphocytic leukemia and myelodysplastic syndrome].
Topics: Acute Disease; Adult; Aged; Chromatography, High Pressure Liquid; Cytarabine; Female; Humans; Infusions, Intravenous; Injections, Subcutaneous; Leukemia; Male; Middle Aged; Myelodysplastic Syndromes | 1987 |
In vitro exposure of leukemic cells to low concentration Arabinosyl Cytosine: no evidence of differentiation inducing activity.
Topics: Acute Disease; Adult; Aged; Bone Marrow; Bone Marrow Cells; Cell Differentiation; Cell Transformation, Neoplastic; Cells, Cultured; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia; Middle Aged; Myelodysplastic Syndromes | 1987 |
In vitro correlates of low dose ara-C efficacy: clinical, cytogenetic, and bone marrow culture analysis.
Topics: Acute Disease; Adult; Aged; Bone Marrow Cells; Cells, Cultured; Cytarabine; Cytogenetics; Dose-Response Relationship, Drug; Female; Humans; Leukemia; Male; Middle Aged | 1987 |
[Neuromeningeal localizations in acute leukemia and non-Hodgkin's lymphoma. Protocol combining BCNU-cytosine arabinoside].
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cytarabine; Leukemia; Lymphoma, Non-Hodgkin; Meningeal Neoplasms | 1987 |
Evaluation of intensive postremission chemotherapy for adults with acute nonlymphocytic leukemia using high-dose cytosine arabinoside with L-asparaginase and amsacrine with etoposide.
Topics: Acute Disease; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cytarabine; Drug Evaluation; Etoposide; Humans; Leukemia; Middle Aged; Remission Induction; Statistics as Topic | 1987 |
CYTOSAR-U sterile powder: therapeutic biological effects. Proceedings of a symposium. November 30-December 2, 1986, Kalamazoo, MI.
Topics: Acute Disease; Animals; Cytarabine; Humans; Leukemia; Lymphoma | 1987 |
Low-dose ara-C in acute nonlymphocytic leukemia and myelodysplastic syndromes: a review of 20 years' experience.
Topics: Acute Disease; Cytarabine; Humans; Leukemia; Myelodysplastic Syndromes; Prognosis | 1987 |
High-dose cytosine arabinoside and daunorubicin as consolidation therapy for acute nonlymphocytic leukemia in first remission: an update.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Humans; Leukemia; Middle Aged; Prognosis | 1987 |
Pharmacokinetic parameters of 1-beta-D-arabinofuranosylcytosine (ara-C) and their relationship to intracellular metabolism of ara-C, toxicity, and response of patients with acute nonlymphocytic leukemia treated with conventional and high-dose ara-C.
Topics: Acute Disease; Animals; Arabinofuranosylcytosine Triphosphate; Arabinofuranosyluracil; Cytarabine; Drug Administration Schedule; Humans; Leukemia; Leukemia L1210; Metabolic Clearance Rate; Mice; Uridine Kinase | 1987 |
High-dose cytosine arabinoside and mitoxantrone in high-risk acute nonlymphoblastic leukemia.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Leukemia; Male; Middle Aged; Mitoxantrone | 1987 |
ara-C in plasma and ara-CTP in leukemic cells after subcutaneous injection and continuous intravenous infusion of ara-C in patients with acute nonlymphoblastic leukemia.
Topics: Acute Disease; Adult; Aged; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cytarabine; Female; Humans; Infusions, Intravenous; Injections, Subcutaneous; Leukemia; Male; Metabolic Clearance Rate; Middle Aged | 1987 |
Studies of ara-C metabolism in acute leukemia.
Topics: Acute Disease; Arabinofuranosylcytosine Triphosphate; Bromodeoxyuridine; Cell Line; Cytarabine; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Resistance; Humans; Leukemia; Thymidine | 1987 |
Cell cycle and drug sensitivity studies of leukemic cells that appear relevant in determining response to chemotherapy in acute nonlymphocytic leukemia.
Topics: Acute Disease; Bone Marrow; Bromodeoxyuridine; Cell Cycle; Cytarabine; DNA Replication; DNA, Neoplasm; Humans; Leukemia | 1987 |
High-dose cytosine arabinoside in the consolidation therapy of acute nonlymphocytic leukemia in remission.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Female; Humans; Leukemia; Male; Methotrexate; Methylprednisolone; Middle Aged | 1987 |
Sequential high-dose ara-C and asparaginase versus high-dose ara-C alone in the treatment of patients with relapsed and refractory acute leukemias.
Topics: Acute Disease; Asparaginase; Cerebellar Diseases; Cytarabine; Diarrhea; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation; Humans; Leukemia; Neoplasm Recurrence, Local | 1987 |
Long-term relapse-free survival in childhood acute nonlymphocytic leukemia.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Diterpenes; Dose-Response Relationship, Drug; Doxorubicin; Humans; Leukemia; Retinyl Esters; Thioguanine; Vitamin A | 1987 |
Pediatric Oncology Group Study of in vitro clonal growth patterns of leukemic cells in childhood acute nonlymphocytic leukemia as a predictor of induction response.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Child; Clone Cells; Cytarabine; Daunorubicin; Dexamethasone; Humans; Leukemia; Prognosis; Remission Induction; Thioguanine; Tumor Stem Cell Assay; Vincristine | 1987 |
Preliminary results of consolidation therapy with high-dose cytosine arabinoside for patients with bad-risk or relapsed acute leukemia or lymphoblastic non-Hodgkin's lymphoma.
Topics: Acute Disease; Adolescent; Adult; Cytarabine; Female; Humans; Leukemia; Lymphoma, Non-Hodgkin; Male; Middle Aged; Neoplasm Recurrence, Local; Risk | 1987 |
Small-dose cytosine arabinoside in the treatment of elderly patients with acute leukemia and refractory anemia with excess of blast.
Topics: Acute Disease; Aged; Anemia, Refractory, with Excess of Blasts; Bone Marrow Diseases; Cytarabine; Humans; Infections; Injections, Subcutaneous; Leukemia; Male; Middle Aged; Nausea | 1986 |
[A phase II study of N4-palmitoyl-1-beta-D-arabinofuranosylcytosine (PL-AC) in patients with acute leukemia and myelodysplastic syndromes. Cooperative Study Group for PL-AC].
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Cytarabine; Drug Evaluation; Female; Humans; Leukemia; Male; Middle Aged; Myelodysplastic Syndromes | 1987 |
Low-dose Ara-C in myelodysplastic syndromes and acute nonlymphoid leukemia. Experience with seven patients.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Leukemia; Male; Middle Aged; Myelodysplastic Syndromes | 1987 |
The use of amsacrine plus intermediate-dose cytosine arabinoside in relapsed and refractory acute nonlymphocytic leukemia.
Topics: Acute Disease; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Leukemia; Middle Aged; Remission Induction | 1987 |
Serum zinc and copper as prognostic factors in acute nonlymphocytic leukemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Copper; Cytarabine; Daunorubicin; Female; Humans; Leukemia; Male; Middle Aged; Prognosis; Remission Induction; Vincristine; Zinc | 1987 |
Treatment of refractory acute leukemia with high-dose cytosine arabinoside.
Topics: Acute Disease; Adolescent; Adult; Cytarabine; Female; Hepatitis B virus; Humans; Leukemia; Male; Middle Aged | 1987 |
[High-dose cytosine arabinoside and L-asparaginase in the treatment of refractory or recurrent acute non-lymphoblastic leukemia].
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged; Neoplasm Recurrence, Local; Remission Induction | 1987 |
Cell kinetic effect of low dose arabinosyl cytosine.
Topics: Acute Disease; Bone Marrow; Cell Cycle; Cytarabine; Humans; Leukemia; Time Factors | 1987 |
Variables predicting response to high dose cytosine arabinoside therapy in patients with refractory acute leukemia.
Topics: Acute Disease; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia | 1987 |
High-dose VP-16 with intermediate-dose cytosine arabinoside in the treatment of relapsed acute nonlymphocytic leukemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Evaluation; Female; Humans; Leukemia; Liver; Male; Middle Aged; Podophyllotoxin; Recurrence; Time Factors | 1987 |
Pharmacokinetic studies of intermediate-to high-dose 1-beta-D-arabinofuranosylcytosine in children with acute leukemia and lymphoma.
Topics: Acute Disease; Child; Chromatography, High Pressure Liquid; Cytarabine; Humans; Leukemia; Lymphoma, Non-Hodgkin | 1987 |
High-dose cytosine arabinoside, daunomycin and 6-thioguanine in relapsed or refractory acute nonlymphocytic leukemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Diseases; Cytarabine; Daunorubicin; Gastrointestinal Diseases; Humans; Leukemia; Recurrence; Remission Induction; Thioguanine | 1987 |
Acute neurological toxicity of intrathecal cytosine arabinoside. A case report.
Topics: Acute Disease; Adult; Brain Neoplasms; Cytarabine; Humans; Male; Nervous System Diseases | 1986 |
Clinical effect of low dose ara-C in twenty patients with acute nonlymphocytic leukemia, atypical leukemia, and refractory anemia with excess of blasts.
Topics: Acute Disease; Adult; Aged; Anemia, Refractory; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged | 1986 |
Effect of cytosine arabinoside on leukemic blast cell colonies.
Topics: Acute Disease; Adolescent; Adult; Aged; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged; Neoplastic Stem Cells | 1986 |
[High-dose Ara-C treatment of acute leukemia].
Topics: Acute Disease; Antineoplastic Agents; Cytarabine; Drug Resistance; Humans; Leukemia | 1986 |
Metabolism of ara-C by blast cells from patients with ANLL.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Cytarabine; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Resistance; Female; Humans; Leukemia; Male; Middle Aged | 1986 |
Comprehensive protective care in the management of acute leukemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cross Infection; Cytarabine; Daunorubicin; Humans; Leukemia; Middle Aged; Patient Care Planning; Prednisone; Thioguanine; Vincristine | 1986 |
[A new drug and current strategy in the treatment of acute non-lymphocytic leukemia in adults].
Topics: Acute Disease; Adult; Aminoacridines; Amsacrine; Anthraquinones; Antineoplastic Agents; Cytarabine; Drug Administration Schedule; Etoposide; Humans; Leukemia; Mitoxantrone | 1986 |
Low-dose Ara-C can cause complete remission of acute non-lymphocytic leukemia: differentiation induction?
Topics: Acute Disease; Adolescent; Adult; Bone Marrow; Cell Differentiation; Child, Preschool; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged; Remission Induction | 1986 |
[Strategy of chemotherapy of a patient with acute leukemia based on the mechanism of action of drugs].
Topics: Acute Disease; Cytarabine; Erythrocytes; Humans; Kinetics; Leukemia; Mercaptopurine | 1986 |
[Prognostic factors related to remission duration and the effects of maintenance therapy in BHAC-DMP therapy in adult acute non-lymphocytic leukemia patients].
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Deoxycytidine Monophosphate; Humans; Leukemia; Middle Aged; Prognosis; Regression Analysis; Remission Induction | 1986 |
[Intermediate- and high-dose cytosine arabinoside therapy in acute refractory leukemia].
Topics: Acute Disease; Adult; Cytarabine; Drug Administration Schedule; Drug Resistance; Female; Humans; Leukemia; Male; Middle Aged | 1987 |
Prolonged unmaintained remission after intensive consolidation therapy in adult acute nonlymphocytic leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Humans; Leukemia; Middle Aged; Mycoses; Pilot Projects | 1987 |
Etoposide in combination with cytarabine, doxorubicin, and 6-thioguanine for treatment of acute nonlymphoblastic leukemia in a protocol adjusted for age.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Bone Marrow; Cytarabine; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Leukemia; Male; Middle Aged; Thioguanine | 1987 |
Limited efficacy of a four-day course of high-dose cytosine arabinoside in the treatment of poor-risk patients with acute nonlymphocytic leukemia.
Topics: Acute Disease; Adult; Age Factors; Aged; Aged, 80 and over; Cytarabine; Humans; Leukemia; Middle Aged; Pilot Projects; Prognosis; Risk; Time Factors | 1986 |
Membrane transport influences the rate of accumulation of cytosine arabinoside in human leukemia cells.
Topics: Acute Disease; Adult; Animals; Biological Transport; Carcinoma, Ehrlich Tumor; Cell Line; Cell Membrane; Cytarabine; Humans; Kinetics; Leukemia; Leukemia L5178; Leukemia P388; Mathematics; Mice | 1987 |
High-dose cytosine arabinoside as the initial treatment of poor-risk patients with acute nonlymphocytic leukemia: a Leukemia Intergroup Study.
Topics: Acute Disease; Aged; Blood Cell Count; Bone Marrow; Cytarabine; Hematopoiesis; Humans; Leukemia; Prognosis; Statistics as Topic; Time Factors | 1987 |
[Diminished bone marrow fibrosis on autopsy in a patient with acute myelofibrosis following chemotherapy].
Topics: Acute Disease; Bone Marrow; Cytarabine; Daunorubicin; Humans; Male; Middle Aged; Primary Myelofibrosis | 1986 |
[Cytosine arabinoside as a polyvalent drug in the treatment of acute non-lymphoid leukemias].
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Biological Availability; Cell Differentiation; Cytarabine; DNA Replication; Humans; Infusions, Intravenous; Injections, Intravenous; Injections, Subcutaneous; Leukemia; Lymphocytes | 1986 |
[Therapeutic effects of a combination of intermediate-dose cytosine arabinoside, adriamycin and vincristine in relapsed acute leukemia].
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Doxorubicin; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Leukemia; Male; Middle Aged; Recurrence; Vincristine | 1987 |
[Treatment of a case of childhood acute non-lymphocytic leukemia (ANLL) using high-dose cytosine arabinoside for intensification of early therapy].
Topics: Aclarubicin; Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Administration Schedule; Female; Humans; Leukemia; Methotrexate; Naphthacenes; Vincristine | 1987 |
High-dose, continuous-infusion cyclophosphamide, cytarabine, vincristine, and prednisone for remission induction in refractory adult acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Female; Hematologic Diseases; Humans; Leukemia; Male; Middle Aged; Prednisone; Vincristine | 1987 |
Abrogation of the prognostic significance of low leukemic cell retention of cytosine arabinoside triphosphate by intensification of therapy and by alteration in the dose and schedule of administration of cytosine arabinoside.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Bone Marrow; Cytarabine; Doxorubicin; Humans; Leukemia; Middle Aged; Neoplasm Proteins; Phosphorylation; Prognosis | 1987 |
[Modified VAPA therapy in children with acute nonlymphocytic leukemia].
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Doxorubicin; Female; Humans; Infant; Leukemia; Male; Methotrexate; Methylprednisolone; Metoclopramide; Prognosis; Remission Induction; Vincristine | 1986 |
Treatment of acute leukemia with amsacrine and high-dose cytarabine.
Topics: Acute Disease; Aminoacridines; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Diarrhea; Dose-Response Relationship, Drug; Humans; Leukemia; Nausea | 1985 |
Amsacrine with high-dose cytarabine in acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Aminoacridines; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Hematologic Diseases; Humans; Leukemia; Middle Aged | 1985 |
SQ chemotherapy at home.
Topics: Acute Disease; Cytarabine; Humans; Injections, Subcutaneous; Leukemia; Self Administration | 1985 |
Treatment of refractory leukemia with high-dose cytosine arabinoside.
Topics: Acute Disease; Adult; Aged; Cytarabine; Female; Humans; Leukemia; Leukemia, Myeloid; Male; Middle Aged | 1985 |
Chemotherapy of acute leukemia in adults.
Topics: Aclarubicin; Acute Disease; Adult; Antineoplastic Agents; Cytarabine; Doxorubicin; Drug Evaluation; Humans; Interferon Type I; Leukemia; Naphthacenes | 1985 |
[Induction of remission by sequential treatment with cytosine arabinoside (araC/high dose) and L-asparaginase].
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Cytarabine; Drug Administration Schedule; Female; Humans; Leukemia; Leukemia, Lymphoid; Male; Middle Aged; Podophyllotoxin | 1985 |
Low dose cytarabine in acute non-lymphoblastic leukemia or myelodysplastic syndrome: report of six cases and review of the literature.
Topics: Acute Disease; Aged; Anemia, Aplastic; Bone Marrow; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged; Recurrence | 1985 |
Leukemia relapse in long-term survivors of acute leukemia.
Topics: Actuarial Analysis; Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Child; Child, Preschool; Cytarabine; Daunorubicin; Female; Health Surveys; Humans; Infant; Japan; Leukemia; Leukemia, Lymphoid; Male; Mercaptopurine; Middle Aged; Nervous System Neoplasms; Prednisolone; Recurrence; Testicular Neoplasms | 1985 |
Low-dose cytosine arabinoside (Ara-C) therapy in the myelodysplastic syndromes and acute leukemia.
Topics: Acute Disease; Adult; Aged; Bone Marrow; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Injections, Subcutaneous; Leukemia; Leukemia, Myeloid; Male; Middle Aged; Preleukemia | 1985 |
Idarubicin alone or in combination with cytarabine and etoposide (3 + 3 + 5 protocol) in acute non-lymphoblastic leukaemia.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Idarubicin; Leukemia; Male; Middle Aged | 1985 |
High-dose cytosine arabinoside in the treatment of resistant acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Child; Cytarabine; Drug Resistance; Female; Humans; Leukemia; Leukemia, Myeloid; Male; Middle Aged; Recurrence; Time Factors | 1985 |
Sequential high-dose cytosine arabinoside and L-asparaginase in childhood leukemia in relapse.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bacterial Infections; Child; Child, Preschool; Cytarabine; Female; Humans; Infant; Leukemia; Leukemia, Lymphoid; Male; Neutropenia; Recurrence; Thrombocytopenia | 1985 |
Sequential high-dose cytosine arabinoside-asparaginase treatment in advanced childhood leukemia.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cytarabine; Drug Evaluation; Female; Humans; Infant; Infusions, Parenteral; Injections, Intramuscular; Leukemia; Leukemia, Lymphoid; Male; Recurrence; Time Factors | 1985 |
[Gastrointestinal symptoms of aclacinomycin A in patients with adult acute nonlymphocytic leukemia--comparison of BH-AC-DMP therapy and BH-AC-AMP therapy].
Topics: Aclarubicin; Acute Disease; Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Digestive System; Female; Gastrointestinal Diseases; Humans; Leukemia; Male; Mercaptopurine; Naphthacenes; Prednisolone | 1985 |
Risk factors in long-term sequelae of central nervous system prophylaxis in successfully treated children with acute lymphocytic leukemia.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Diseases; Brain Neoplasms; Child; Child, Preschool; Cytarabine; Electroencephalography; Female; Humans; Infant; Leukemia, Lymphoid; Male; Methotrexate; Neurologic Examination; Risk; Time Factors; Tomography, X-Ray Computed | 1985 |
Bone marrow response to chemotherapy in acute lymphocytic leukaemia and acute non-lymphocytic leukaemia.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Asparaginase; Bone Marrow; Bone Marrow Cells; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Humans; Leukemia; Leukemia, Lymphoid; Lymphocyte Depletion; Middle Aged; Plasma Cells; Prednisone; Thioguanine; Vincristine | 1985 |
Control of acute transformation in chronic granulocytic leukaemia with low-dose cytosine arabinoside.
Topics: Acute Disease; Adult; Cell Transformation, Neoplastic; Cytarabine; Humans; Leukemia, Myeloid; Male | 1985 |
[High-dose treatment].
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cytarabine; Daunorubicin; Doxorubicin; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Humans; Infusions, Parenteral; Leucovorin; Leukemia; Methotrexate; Neoplasms | 1985 |
Continuous infusion of high-dose cytosine arabinoside for treatment of childhood acute leukemia and non-Hodgkin's lymphoma in relapse.
Topics: Acute Disease; Adolescent; Adult; B-Lymphocytes; Bacterial Infections; Burkitt Lymphoma; Cerebellar Ataxia; Child; Child, Preschool; Cytarabine; Female; Gastrointestinal Diseases; Humans; Leukemia; Leukemia, Lymphoid; Lymphoma; Male; Neutropenia; Recurrence; Thrombocytopenia | 1985 |
[Non-hematologic toxicity in high-dose cytarabine therapy].
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Brain Diseases; Cytarabine; Dose-Response Relationship, Drug; Humans; Keratitis; Leukemia; Skin Diseases; Vomiting | 1985 |
[High-dose cytarabine treatment in acute leukemias and leukemic meningiosis: clinical aspects and pharmacokinetics].
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Kinetics; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Meningeal Neoplasms; Middle Aged | 1985 |
[Experiences with HD-Ara C treatment in leukemia patients].
Topics: Acute Disease; Aminoacridines; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia; Leukemia, Myeloid, Acute | 1985 |
[Principles of high-dose cytarabinoside treatment].
Topics: Acute Disease; Bone Marrow; Cell Cycle; Cytarabine; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Resistance; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphoma; Metabolic Clearance Rate; RNA, Neoplasm | 1985 |
[Results of therapy with high-dose cytosine arabinoside].
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged | 1985 |
[High-dose cytosine arabinoside].
Topics: Acute Disease; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia | 1985 |
[Results of high-dose cytarabine therapy. A review].
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma | 1985 |
Remission from central nervous system involvement in adults with acute leukemia. Effect of intensive therapy and prognostic factors.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Humans; Hydrocortisone; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Meningeal Neoplasms; Methotrexate; Prognosis; Radiotherapy Dosage | 1985 |
Bone marrow transplantation for acute leukemia and lymphoma with high-dose cytosine arabinoside and total body irradiation.
Topics: Acute Disease; Adolescent; Adult; Bone Marrow Transplantation; Central Nervous System Diseases; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Diarrhea; Graft vs Host Disease; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphoma; Pulmonary Fibrosis; Skin Diseases; Whole-Body Irradiation | 1985 |
Central nervous system toxicity with high-dose cytosine arabinoside.
Topics: Acute Disease; Aging; Central Nervous System Diseases; Combined Modality Therapy; Cytarabine; Drug Evaluation; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphoma; Middle Aged; Whole-Body Irradiation | 1985 |
Summary overview of clinical session.
Topics: Acute Disease; Adult; Antineoplastic Agents; Bone Marrow Transplantation; Child; Cytarabine; Follow-Up Studies; HLA Antigens; Humans; Leukemia | 1985 |
[Thrombocyte replacement in hematologic diseases].
Topics: Acute Disease; Adolescent; Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Blood Platelets; Blood Transfusion; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Daunorubicin; Disseminated Intravascular Coagulation; Doxorubicin; Fever; Hematologic Diseases; Hemorrhage; Histocompatibility; HLA Antigens; Humans; Leukemia; Leukemia, Myeloid, Acute; Middle Aged; Plateletpheresis | 1985 |
Consequences of intensive therapy of acute lymphoblastic leukemia in children in initial complete remission lasting more than five years.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Female; Humans; Leukemia, Lymphoid; Male; Mental Disorders; Mercaptopurine; Methotrexate; Nervous System Diseases; Prednisone; Time Factors; Vincristine | 1985 |
Low-dose cytarabine: persistence of a clonal abnormality during complete remission of acute nonlymphocytic leukemia.
Topics: Acute Disease; Aged; Chromosome Aberrations; Clone Cells; Cytarabine; Humans; Leukemia; Male; Metaphase; Y Chromosome | 1986 |
Acute megakaryoblastic leukaemia: a prospective study of its identification and treatment.
Topics: Acute Disease; Adolescent; Adult; Bone Marrow; Child; Cytarabine; Female; Hematologic Tests; Humans; Male; Primary Myelofibrosis; Prospective Studies; Thrombocythemia, Essential | 1986 |
[Etoposide (VP 16/NK 171) and cytosine arabinoside combination chemotherapy in refractory childhood leukemia].
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Drug Administration Schedule; Etoposide; Female; Humans; Infant; Leukemia; Lymphoma; Male; Myeloproliferative Disorders; Podophyllotoxin | 1986 |
Cerebrospinal fluid concentrations of cytosine arabinoside during intravenous therapy with intermediate dose: a preliminary report.
Topics: Acute Disease; Adolescent; Adult; Cytarabine; Humans; Infusions, Parenteral; Leukemia; Male | 1985 |
Low-dose cytosine arabinoside treatment for acute nonlymphocytic leukemia in elderly patients.
Topics: Acute Disease; Aged; Ambulatory Care; Bone Marrow; Cytarabine; Hematologic Diseases; Humans; Injections, Subcutaneous; Leukemia; Nausea; Recurrence | 1985 |
Low dose cytosine arabinoside in the treatment of acute non-lymphocytic leukaemia.
Topics: Acute Disease; Adult; Aged; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia; Male; Middle Aged | 1985 |
Clinical pharmacology of low-dose cytosine arabinoside.
Topics: Acute Disease; Cytarabine; Delayed-Action Preparations; Dose-Response Relationship, Drug; Humans; Infusions, Parenteral; Leukemia; Preleukemia; Radioimmunoassay | 1985 |
High-dose cytosine arabinoside and daunorubicin as consolidation therapy for acute nonlymphocytic leukemia in first remission: a pilot study.
Topics: Acute Disease; Adolescent; Adult; Aged; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leukemia; Life Expectancy; Male; Middle Aged; Recurrence | 1985 |
Monitoring the remission induction therapy of acute nonlymphoblastic leukemia by bone marrow cell culture criteria.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cells, Cultured; Colony-Forming Units Assay; Cytarabine; Daunorubicin; Humans; Leukemia; Monitoring, Physiologic; Thioguanine | 1985 |
[Myelodysplastic syndromes].
Topics: Acute Disease; Androgens; Cytarabine; Glucocorticoids; Hemorrhage; Humans; Immunotherapy; Infections; Leukemia; Myelodysplastic Syndromes; Prognosis; Vitamins | 1985 |
Treatment of leukemia with low-dose ara-C: a study of 160 cases.
Topics: Acute Disease; Aged; Aging; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia | 1985 |
Low-dose cytosine arabinoside in the treatment of acute nonlymphoblastic leukemia and myelodysplastic syndromes.
Topics: Acute Disease; Adult; Aged; Bone Marrow; Bone Marrow Diseases; Cells, Cultured; Cytarabine; Granulocytes; Hematopoiesis; Humans; Leukemia; Middle Aged; Syndrome | 1985 |
Meningeal involvement in patients with acute nonlymphocytic leukemia. Incidence, management, and predictive factors.
Topics: Actuarial Analysis; Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia; Male; Meningeal Neoplasms; Methotrexate; Middle Aged; Prognosis | 1985 |
Modulation of 1-beta-D-arabinofuranosylcytosine metabolism by thymidine in human acute leukemia.
Topics: Acute Disease; Cytarabine; Deoxycytosine Nucleotides; DNA; Drug Interactions; Drug Therapy, Combination; Humans; Leukemia; Thymidine; Thymine Nucleotides | 1985 |
Terminal deoxynucleotidyl transferase-positive acute leukemias evolving from a myelodysplastic syndrome.
Topics: Acute Disease; Adult; Cytarabine; DNA Nucleotidylexotransferase; DNA Nucleotidyltransferases; Humans; Leukemia; Myeloproliferative Disorders; Preleukemia | 1985 |
Low-dose arabinosyl cytosine in acute leukemia after a myelodysplastic syndrome and in elderly leukemia.
Topics: Acute Disease; Adult; Aged; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia; Middle Aged; Myeloproliferative Disorders; Preleukemia | 1985 |
Relationship between leukemic cell retention of cytosine arabinoside triphosphate and the duration of remission in patients with acute non-lymphocytic leukemia.
Topics: Acute Disease; Adult; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged; Phosphorylation; Time Factors | 1985 |
Daunomycin administered by continuous intravenous infusion is effective in the treatment of acute nonlymphocytic leukaemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Humans; Infusions, Parenteral; Leukemia; Middle Aged; Thioguanine; Time Factors | 1985 |
Outcome of aggressive induction therapy in acute non-lymphocytic leukaemia.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia; Male; Mercaptopurine; Prednisolone; Vincristine | 1985 |
Favourable remission rate by repeating low dose ARA-C treatment in ANLL and RAEB.
Topics: Acute Disease; Adolescent; Adult; Aged; Anemia, Aplastic; Bone Marrow; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged | 1985 |
Treatment of acute nonlymphocytic leukemia in young and elderly patients.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Daunorubicin; Female; Humans; Leukemia; Male; Middle Aged; Prognosis; Recurrence; Sex Factors; Vincristine | 1985 |
Subacute pulmonary failure complicating therapy with high-dose Ara-C in acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Cytarabine; Drug Evaluation; Female; Humans; Leukemia; Lung Diseases; Male; Middle Aged; Pulmonary Edema; Respiratory Insufficiency | 1985 |
Treatment of dysmyelopoietic/leukemic syndromes with myelofibrosis and megakaryocytic hyperplasia with large doses of cytosine arabinoside.
Topics: Acute Disease; Adult; Aged; Biopsy; Blood Cell Count; Bone Marrow; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Hyperplasia; Leukemia; Male; Megakaryocytes; Middle Aged; Myelodysplastic Syndromes; Pancytopenia; Primary Myelofibrosis; Thrombocythemia, Essential | 1985 |
Low-dose Ara-C in treatment of overt acute leukaemia.
Topics: Acute Disease; Cytarabine; Humans; Leukemia | 1985 |
Cytosine arabinoside and herpes zoster.
Topics: Acute Disease; Adolescent; Adult; Child, Preschool; Cytarabine; Herpes Zoster; Herpesvirus 3, Human; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Remission, Spontaneous; Time Factors | 1971 |
Cytosine arabinoside in the treatment of acute myeloblastic leukaemia.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Age Factors; Aged; Amino Sugars; Antibiotics, Antineoplastic; Antineoplastic Agents; Cytarabine; Drug Synergism; Female; Follow-Up Studies; Glycosides; Humans; Injections, Intravenous; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisolone; Pregnancy; Remission, Spontaneous; Time Factors | 1971 |
Combination chemotherapy: rationale for schedule selection and use of agents with independent toxicities in phase I and II clinical trials.
Topics: Acute Disease; Adult; Agranulocytosis; BCG Vaccine; Bleomycin; Cytarabine; Doxorubicin; Drug Combinations; Humans; Immunosuppression Therapy; Leukemia; Lymphopenia; Mitosis; Nitrogen Mustard Compounds; Prednisone; Thrombocytopenia; Vincristine | 1973 |
[Acute undifferentiated leukemia--acute lymphocytic leukemia of adults. Differential diagnosis, prognosis, results of therapy].
Topics: Acute Disease; Adult; Age Factors; Aged; Aminosalicylic Acids; Asparaginase; Cytarabine; Cytodiagnosis; Cytoplasm; Daunorubicin; Diagnosis, Differential; Drug Therapy, Combination; Female; Glycogen; Histocytochemistry; Humans; Leukemia; Leukemia, Lymphoid; Male; Methotrexate; Middle Aged; Prognosis; Staining and Labeling; Vincristine | 1974 |
Adult acute leukaemia.
Topics: Acute Disease; Administration, Oral; Adult; Aged; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Cytosine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Humans; Injections, Intravenous; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Middle Aged; Prednisone; Remission, Spontaneous; Staining and Labeling; Thioguanine; Vincristine | 1974 |
Bone-marrow transplantation following combination chemotherapy immunosuppression (B.A.C.T.) in patients with acute leukemia.
Topics: ABO Blood-Group System; Acute Disease; Blood Group Incompatibility; Bone Marrow Cells; Bone Marrow Transplantation; Child; Chimera; Cyclophosphamide; Cytarabine; Drug Resistance; Drug Therapy, Combination; Female; Graft vs Host Reaction; Histocompatibility; Humans; Leukemia; Leukemia, Lymphoid; Male; Methotrexate; Nitrosourea Compounds; Thioguanine; Transplantation, Homologous | 1974 |
[The acute leukemia in adults, therapy and prognosis].
Topics: Acute Disease; Adolescent; Adult; Aged; Cyclophosphamide; Cytarabine; Drug Resistance, Microbial; Female; Humans; Leukemia; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Prognosis; Vincristine | 1969 |
[Therapy of acute leukoses].
Topics: Acute Disease; Adult; Antineoplastic Agents; Asparaginase; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Infection Control; Leukemia; Life Expectancy; Male; Mercaptopurine; Methotrexate; Middle Aged; Patient Isolators; Prednisolone; Thioguanine; Time Factors; Vincristine | 1973 |
Studies of cellular proliferation in human leukemia. 3. Behavior of leukemic cells in three adults with acute leukemia given continuous infusions of 3H-thymidine for 8 or 10 days.
Topics: Acute Disease; Adult; Aged; Autoradiography; Bone Marrow; Bone Marrow Cells; Cell Division; Cell Nucleus; Culture Techniques; Cytarabine; Down Syndrome; Female; Floxuridine; Humans; Karyotyping; Leukemia; Leukocytes; Lymphocytes; Male; Mitosis; Prednisone; Thioguanine; Thymidine; Tritium; Vincristine | 1970 |
Acute leukemia and infection.
Topics: Acute Disease; Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Agranulocytosis; Aspergillosis; Candidiasis; Cytarabine; Female; Humans; Leukemia; Male; Mercaptopurine; Methotrexate; Middle Aged; Mucormycosis; Nocardia Infections; Prednisone; Proteus Infections; Pseudomonas Infections; Sepsis; Staphylococcal Infections; Strongyloidiasis; Uracil; Vinblastine | 1967 |
Acute promyelocytic leukemia in pregnancy.
Topics: Acute Disease; Adult; Afibrinogenemia; Blood Cell Count; Blood Coagulation Disorders; Blood Transfusion; Bone Marrow Examination; Cytarabine; Ecchymosis; Estrogens, Conjugated (USP); Factor V Deficiency; Female; Humans; Leukemia, Myeloid; Leukocyte Count; Pregnancy; Pregnancy Complications, Hematologic; Prothrombin Time; Remission, Spontaneous; Thioguanine; Uterine Hemorrhage | 1973 |
Treatment of hyperacute graft-versus-host disease in mice with cytosine arabinoside.
Topics: Acute Disease; Animals; Antilymphocyte Serum; Cyclophosphamide; Cytarabine; Graft vs Host Disease; Graft vs Host Reaction; Lymphocyte Transfusion; Methods; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; Procarbazine; Tissue Donors; Transplantation, Homologous | 1972 |
Letter: Febrile response to cytarabine.
Topics: Acute Disease; Adult; Cytarabine; Female; Fever; Humans; Leukemia | 1974 |
[Treatment of adult acute leukemia with a combination of cytosine arabinoside, vincristine, 6-mercaptopurine, prednisolone, and L-asparaginase (author's transl)].
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Agents; Asparaginase; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Mercaptopurine; Middle Aged; Prednisolone; Vincristine | 1974 |
[Anhydro-arabinosylcytosine (cyclocytidine) in the therapy of acute leukemia].
Topics: Acute Disease; Adolescent; Adult; Aged; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged | 1974 |
DCMP therapy in acute leukemia--the experimental and clinical study.
Topics: Acute Disease; Adult; Animals; Child; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia; Leukemia L1210; Mercaptopurine; Prednisolone; Time Factors | 1974 |
Adriamycin in the treatment of acute leukaemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Resistance; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Middle Aged; Remission, Spontaneous | 1972 |
Combination chemotherapy of adult acute nonlymphoblastic leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Bone Marrow; Cytarabine; Drug Synergism; Female; Humans; Hydroxyurea; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Nausea; Remission, Spontaneous; Thioguanine; Vomiting | 1972 |
Observations on the myelocyte to tissue transit time (MTT) in acute leukaemia and other proliferative disorders.
Topics: Acute Disease; Adult; Cytarabine; Fluorine; Hematologic Diseases; Hematopoiesis; Humans; Isoflurophate; Leukemia, Myeloid; Leukocyte Count; Leukocytes; Myeloproliferative Disorders; Radioisotopes; Remission, Spontaneous; Thioguanine; Time Factors | 1972 |
[Effect of daunomycin and adriamycin in cytostatic combination therapy of acute leukoses of the adult].
Topics: Acute Disease; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Blood Coagulation Disorders; Bone Marrow Diseases; Carbenicillin; Cytarabine; Daunorubicin; Drug Synergism; Female; Glycosides; Hair; Heart Diseases; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisolone; Remission, Spontaneous; Skin Diseases; Vincristine | 1972 |
The outlook for the adult with acute leukaemia, 1972.
Topics: Acute Disease; Adolescent; Adult; Aged; Bacterial Infections; Cytarabine; Drug Combinations; Female; Hemorrhage; Humans; Hydroxyurea; Length of Stay; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Patient Isolators; Prednisone; Remission, Spontaneous; Thioguanine | 1972 |
Therapy of acute myelocytic leukemia. Daunomycin contrasted with a combination of cytosine arabinoside and 6-thioguanine.
Topics: Acute Disease; Adolescent; Adult; Aged; Cytarabine; Daunorubicin; Drug Combinations; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Remission, Spontaneous; Thioguanine | 1972 |
Urticaria pigmentosa and acute lymphoblastic leukemia.
Topics: Acute Disease; Asparaginase; Bone Marrow Examination; Bone Neoplasms; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Humans; Leukemia, Lymphoid; Male; Mercaptopurine; Methotrexate; Prednisone; Radiography; Remission, Spontaneous; Urticaria Pigmentosa; Vincristine | 1973 |
Leukemoid reaction in acute lymphoblastic leukemia: a response to chemotherapy.
Topics: Acute Disease; Adult; Agranulocytosis; Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Cytarabine; Humans; Leukemia, Lymphoid; Leukemoid Reaction; Male; Prednisone; Vincristine | 1973 |
Acute myeloblastic leukemia during pregnancy.
Topics: Acute Disease; Cytarabine; Female; Humans; Infant, Newborn; Leukemia, Myeloid, Acute; Pregnancy; Pregnancy Complications, Hematologic; Thioguanine | 1972 |
Acute leukemia presenting as a breast mass.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Biopsy, Needle; Breast Neoplasms; Child; Cytarabine; Daunorubicin; Diagnosis, Differential; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Menarche; Mercaptopurine; Methotrexate; Prednisolone; Sulfates; Vincristine | 1973 |
Optimism in leukemia treatment.
Topics: Acute Disease; Adult; Child; Cyclophosphamide; Cytarabine; Humans; Hydroxyurea; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Prednisolone; Thioguanine; Vincristine | 1973 |
Editorial: Treatment of childhood leukemia.
Topics: Acute Disease; Age Factors; Central Nervous System; Central Nervous System Diseases; Child; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Humans; Injections, Spinal; Leukemia, Lymphoid; Mercaptopurine; Methotrexate; Prednisone; Radiation Effects; Remission, Spontaneous; Time Factors; Vincristine | 1973 |
Adult acute leukaemia--a suitable case for treatment?
Topics: Acute Disease; Adult; Aged; Agranulocytosis; Anemia; Blood Platelet Disorders; Blood Transfusion; Bone Marrow Diseases; Cytarabine; Daunorubicin; Female; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Mouth Diseases; Ulcer | 1973 |
[Acute lymphatic leukemia in adults. Therapy and prognosis in comparison with acute myelogenous leukemia].
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Asparaginase; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Methylprednisolone; Middle Aged; Paresis; Prognosis; Radiotherapy Dosage; Remission, Spontaneous; Vincristine | 1974 |
Neutralization in vivo of Lewis antibodies. Report of two cases.
Topics: Acute Disease; Aged; Antigen-Antibody Reactions; Blood Group Incompatibility; Coombs Test; Cytarabine; Hematocrit; Humans; Leukemia, Myeloid; Lewis Blood Group Antigens; Male; Middle Aged; Stomach Neoplasms; Transfusion Reaction | 1974 |
Agar culture studies in 127 cases of untreated acute leukemia: the prognostic value of reclassification of leukemia according to in vitro growth characteristics.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Bone Marrow; Bone Marrow Cells; Cell Division; Cells, Cultured; Child; Clone Cells; Cytarabine; Daunorubicin; Densitometry; Drug Therapy, Combination; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Middle Aged; Prognosis; Remission, Spontaneous; Vincristine | 1974 |
Cytology of the cerebrospinal fluid in children with acute lymphoblastic leukemia.
Topics: Acute Disease; Cell Count; Central Nervous System Diseases; Cerebrospinal Fluid; Child; Cytarabine; Female; Humans; Leukemia, Lymphoid; Methotrexate; Remission, Spontaneous | 1974 |
[Cytosine-arabinoside in the treatment of acute leukemias].
Topics: Acute Disease; Adolescent; Adult; Aged; Child; Child, Preschool; Cytarabine; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Middle Aged; Polycythemia | 1972 |
Proceedings: Treatment of acute leukaemia in adults.
Topics: Acute Disease; Adult; Allopurinol; Anti-Bacterial Agents; Bacterial Infections; Child; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Hydroxyurea; Leukemia; Leukemia, Lymphoid; Metabolic Diseases; Prednisone; Remission, Spontaneous; Thioguanine; Uric Acid; Vincristine | 1974 |
Prognosis of acute leukaemia in adults.
Topics: Acute Disease; Adult; Age Factors; Antineoplastic Agents; Child; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Middle Aged; Prednisolone; Prognosis; Remission, Spontaneous; Thioguanine; Vincristine | 1974 |
[Zoster in the course of acute leukemia in children].
Topics: Acute Disease; Child; Cytarabine; Female; Herpes Zoster; Humans; Leukemia, Lymphoid; Male | 1974 |
Cytologic expressions of spontaneous tumor-specific immunity in an untreated myelomonocytic leukemia. Sustained, complete remission following minimal immunosuppressive therapy.
Topics: Acute Disease; BCG Vaccine; Cytarabine; Drug Therapy, Combination; Female; Humans; Immunity, Cellular; Immunosuppression Therapy; Leukemia, Myeloid; Lymphocytes; Middle Aged; Remission, Spontaneous; Thioguanine | 1974 |
Acute erythraemic myelosis--Di Guglielmo syndrome.
Topics: Acute Disease; Cytarabine; Female; Humans; Infant; Leukemia, Erythroblastic, Acute; Mercaptopurine; Methotrexate; Prednisolone | 1974 |
Proceedings: Cellular kinetics in acute leukemia.
Topics: Acute Disease; Asparaginase; Cell Division; Cell Survival; Cytarabine; DNA; Glucocorticoids; Humans; Leukemia; Methotrexate; Mitosis; Thymidine; Tritium; Vincristine | 1972 |
[Preliminary results of cytosine arabinoside therapy in various chemotherapeutic combinations in acute leukemias].
Topics: Acute Disease; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Combinations; Drug Interactions; Drug Synergism; Humans; Leukemia; Mercaptopurine; Prednisone; Thioguanine | 1972 |
[The effect of cytosine arabinoside on cell kinetics in adult acute leukemia and its correlation to the therapeutic response].
Topics: Acute Disease; Adolescent; Adult; Bone Marrow; Bone Marrow Cells; Cell Count; Cytarabine; Erythropoiesis; Female; Humans; Injections, Intravenous; Leukemia; Male; Middle Aged; Mitosis | 1972 |
[Quadruple combination chemotherapy of acute leukemia using daunomycin, cytosine arabinoside, 6-mercaptopurine riboside and prednisolone].
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Cytarabine; Daunorubicin; Humans; Injections, Intravenous; Leukemia; Mercaptopurine; Middle Aged; Prednisolone | 1972 |
[Polychemotherapy of acute leukemias in children and young persons].
Topics: Acute Disease; Adolescent; Ambulatory Care; Antineoplastic Agents; Asparaginase; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Humans; Immunotherapy; Leukemia; Mercaptopurine; Methotrexate; Prednisolone; Vincristine | 1973 |
[Combination chemotherapy with cytosine arabinoside and daunomycin in childhood acute leukemia].
Topics: Acute Disease; Child; Child, Preschool; Cytarabine; Daunorubicin; Female; Humans; Infant; Leukemia; Male | 1973 |
Proceedings: Management of acute leukemia.
Topics: Acute Disease; Adult; Cyclophosphamide; Cytarabine; Drug Synergism; Drug Therapy, Combination; Humans; Leukemia; Prednisone; Remission, Spontaneous; Vincristine | 1972 |
Cell kinetic patterns in human acute leukemia-evidence for control mechanisms.
Topics: Acute Disease; Bone Marrow; Bone Marrow Cells; Cell Division; Cell Survival; Cytarabine; Humans; Leukemia; Methotrexate; Mitosis; Radiation Effects; Vincristine | 1973 |
[Treatment of acute leukemia with 2,2'-anhydro-1-beta-D-arabinofuranosylcytosine hydrochloride (cyclocytidine) (author's transl)].
Topics: Acute Disease; Adolescent; Adult; Anhydrides; Antineoplastic Agents; Child, Preschool; Cytarabine; Drug Evaluation; Female; Humans; Leukemia; Male; Middle Aged | 1973 |
[Modern treatment of adult acute non-lymphocytic leukemia].
Topics: Acute Disease; Adult; Antineoplastic Agents; Cytarabine; Humans; Leukemia; Methotrexate; Prednisone; Vincristine | 1974 |
Local experience in the treatment of acute non-lymphoblastic leukaemia.
Topics: Acute Disease; Adult; Antineoplastic Agents; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia; Mercaptopurine; Middle Aged; Prednisone; Remission, Spontaneous; Retrospective Studies; Vincristine | 1974 |
Management of acute non-lymphocytic leukaemia.
Topics: Acute Disease; Age Factors; Cytarabine; Daunorubicin; Female; Humans; Injections; Leukemia; Male; Methods; Prognosis; Remission, Spontaneous; Time Factors; Vincristine | 1974 |
[Polychemotherapy of acute leukemias in children and adolescents].
Topics: Acute Disease; Adolescent; Age Factors; Antineoplastic Agents; Asparaginase; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Glucocorticoids; Humans; Leukemia; Mercaptopurine; Methotrexate; Prednisone; Vincristine | 1972 |
[Kinetic aspects of the chemotherapy of acute leukemia in children].
Topics: Acute Disease; Antibiotics, Antineoplastic; Antineoplastic Agents; Child; Cyclophosphamide; Cytarabine; Humans; Leukemia; Mercaptopurine; Methotrexate; Prednisolone; Vinblastine; Vincristine | 1971 |
[Therapy of leukemic meningiosis. I].
Topics: Acute Disease; Adolescent; Child; Child, Preschool; Cytarabine; Electroencephalography; Humans; Infant; Injections, Spinal; Leukemia; Meninges; Methotrexate; Neoplasm Metastasis; Neurologic Manifestations; Recurrence | 1971 |
[Chemotherapy of acute leukemia].
Topics: Acute Disease; Adrenal Cortex Hormones; Adult; Antineoplastic Agents; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Thrombocythemia, Essential; Vincristine | 1967 |
Coordinated changes in biochemical patterns: the effect of cytosine arabinoside and methotrexate on leukocytes from patients with acute granulocytic leukemia.
Topics: Acute Disease; Cytarabine; Deoxyuridine; DNA; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Ligases; Methotrexate; Phosphotransferases; Tetrahydrofolate Dehydrogenase; Thymidine; Thymidine Kinase | 1969 |
Hypersplenism due to disseminated candidiasis in a patient with acute leukemia.
Topics: Acute Disease; Adult; Amphotericin B; Blood Cell Count; Blood Platelets; Candida; Candidiasis; Cytarabine; Feces; Fever; Humans; Hypersplenism; Leukemia; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Nose; Pharynx; Prednisone; Skin; Spleen | 1969 |
Remission induction with cytosine arabinoside and L-asparaginase in acute lymphoblastic leukaemia.
Topics: Acute Disease; Asparaginase; Bone Marrow Diseases; Bone Marrow Examination; Child; Child, Preschool; Cytarabine; Drug Synergism; Female; Humans; Leukemia, Lymphoid; Leukocyte Count; Male | 1969 |
Experience with the use of cytosine arabinoside in adult acute leukaemia.
Topics: Acute Disease; Adolescent; Adult; Cyclophosphamide; Cytarabine; Female; Humans; Injections, Intravenous; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged | 1970 |
Treatment of acute myeloblastic leukaemia.
Topics: Acute Disease; Adult; Child; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute | 1970 |
[Therapy of acute myeloblastic leukemia. Thoughts after preliminary results].
Topics: Acute Disease; Adult; Cyclophosphamide; Cytarabine; Female; Humans; Intensive Care Units; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisolone; Vincristine | 1970 |
[Therapeutic evolution of 63 cases of recent acute myeloblastic leukemias].
Topics: Acute Disease; Aged; Antineoplastic Agents; Asparaginase; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Prednisone; Vincristine | 1971 |
[Treatment of acute leukemia].
Topics: Acute Disease; Adolescent; Adult; Antibiotics, Antineoplastic; Antilymphocyte Serum; Antineoplastic Agents; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Drug Synergism; Female; Humans; Immunotherapy; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Prednisone; Vincristine | 1970 |
[Round table conference--present status and the future of treatment of leukemia].
Topics: Acute Disease; Asparaginase; Cytarabine; Daunorubicin; Glutaminase; Humans; Leukemia; Leukemia, Myeloid; Vinblastine; Vincristine | 1971 |
Cytarabine.
Topics: Acute Disease; Amino Sugars; Anemia; Antibiotics, Antineoplastic; Antineoplastic Agents; Blood Cell Count; Cyclophosphamide; Cytarabine; Glycosides; Humans; Injections, Intravenous; Injections, Subcutaneous; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukopenia; Lymphoma; Prednisone; Remission, Spontaneous; Thioguanine; Thrombocytopenia; Vincristine | 1971 |
Experiences with cytosine arabinoside in childhood leukaemia and lymphoma.
Topics: Acute Disease; Adolescent; Central Nervous System Diseases; Child; Child, Preschool; Cytarabine; Female; Humans; Infant; Injections, Intravenous; Injections, Spinal; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Neoplasm Regression, Spontaneous | 1971 |
Observations on the plasma amino acids of patients with acute leukemia.
Topics: Acute Disease; Alanine; Amino Acids; Asparaginase; Cytarabine; Glucocorticoids; Glutamine; Histidine; Humans; Indicators and Reagents; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Methionine; Methotrexate; Nitrogen; Proline; Threonine; Vincristine | 1971 |
[Treatment of acute leukemias in the infancy with cytosine arabinoside].
Topics: Acute Disease; Child, Preschool; Cytarabine; Female; Humans; Infant; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Remission, Spontaneous | 1971 |
Hyperleukocytosis before the beginning of treatment in acute leukaemia in children and its subsequent repetition at the onset of relapses.
Topics: Acute Disease; Antibiotics, Antineoplastic; Bone Marrow Examination; Child; Cytarabine; Humans; Leukemia; Leukemia, Lymphoid; Leukocytosis; Mercaptopurine; Methotrexate; Prednisone; Prognosis; Recurrence; Vincristine | 1970 |
[Therapy of acute leukemia. 4. Remission induction and remission maintenance therapy].
Topics: Acute Disease; Adolescent; Adrenal Cortex Hormones; Adult; Age Factors; Aged; Asparaginase; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Middle Aged; Remission, Spontaneous; Vincristine | 1971 |
Use of asparaginase in conjunction with cytosine arabinoside in acute leukemia in children.
Topics: Acute Disease; Asparaginase; Blood Cell Count; Blood Platelet Disorders; Bone Marrow Examination; Child; Child, Preschool; Cytarabine; Female; Hemoglobinometry; Humans; Leukemia, Lymphoid; Leukocyte Count; Leukopenia; Male | 1970 |
[Acute leukemia].
Topics: Acute Disease; Asparaginase; Cytarabine; Daunorubicin; Humans; Leukemia | 1970 |
Combinations, schedules, and new agents for the chemotherapy of acute leukemia.
Topics: Acute Disease; Adult; Antineoplastic Agents; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Humans; Leukemia; Leukemia, Lymphoid; Mercaptopurine; Methotrexate; Nitroso Compounds; Prednisone; Urea; Vincristine | 1970 |
[A common therapy program of leukemia for several hospitals].
Topics: Acute Disease; Adult; Asparaginase; Blood Platelets; Blood Transfusion; Cyclophosphamide; Cytarabine; Humans; Leukemia; Leukocytes; Mercaptopurine; Prednisolone; Sweden | 1970 |
[New cytostatics in the treatment of acute leukemias in childhood].
Topics: Acute Disease; Aminopterin; Antineoplastic Agents; Asparaginase; Child; Cortisone; Cyclophosphamide; Cytarabine; Daunorubicin; Evaluation Studies as Topic; Humans; Leukemia; Mercaptopurine; Methotrexate; Prednisone; Vincristine | 1970 |
Cytosine arabinoside. Results of a cooperative study in acute childhood leukemia.
Topics: Acute Disease; Adolescent; Blood Cell Count; Blood Platelets; Bone Marrow; Bone Marrow Cells; Child; Child, Preschool; Cytarabine; Female; Follow-Up Studies; Humans; Injections, Intravenous; Leukemia; Leukocyte Count; Male | 1968 |
Therapy for acute leukemia in adults with cytosine arabinoside (NSC-63878), vincristine (NSC-67574), and prednisone (NSC-10023).
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Agents; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged; Prednisone; Vincristine | 1968 |