cytarabine has been researched along with Abnormalities, Autosome in 296 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 127 (42.91) | 18.7374 |
| 1990's | 67 (22.64) | 18.2507 |
| 2000's | 66 (22.30) | 29.6817 |
| 2010's | 33 (11.15) | 24.3611 |
| 2020's | 3 (1.01) | 2.80 |
| Authors | Studies |
|---|---|
| Cheng, S; Ding, X; Gao, L; Hu, S; Hu, Y; Li, B; Li, Z; Ling, J; Lu, J; Lu, Q; Pan, J; Ribeiro, RC; Wang, J; Wang, Y; Xiao, P; Zheng, J | 1 |
| Arber, DA; Erba, HP | 1 |
| Choi, EJ; Choi, Y; Kim, H; Lee, JH; Lee, KH; Lee, SM; Lee, WS; Park, HS; Park, JH | 1 |
| Grassinger, J; Hart, C; Herr, W; Iberl, S; Müller, G; Schelker, RC | 1 |
| Foran, JM | 1 |
| Chen, Y; Cheng, N; Jiang, Y; Liu, X; Nowak, B; Plunkett, W; Qiang, B | 1 |
| Arellano, M; Carlisle, JW | 1 |
| Gökbuget, N; Wermann, WK | 1 |
| Inoue, A; Mori, A; Suzuki, R; Takitani, K; Tamai, H; Yamazaki, S | 1 |
| Di Bona, E; Finotto, S; Laveder, F; Paolini, R; Pomponi, F; Rodeghiero, F; Ruggeri, M; Sartori, R; Trentin, L; Visco, C | 1 |
| Audisio, E; D'Ardia, S; Di Bello, C; Di Celle, PF; Frairia, C; Inghirami, G; Marmont, F; Messa, E; Pich, A; Riera, L; Sismondi, F; Toppino, D; Vitolo, U | 1 |
| Abraham, R; Barkoh, BA; Luthra, R; Medeiros, LJ; Mehrotra, M; Mishra, BM; Patel, KP; Ravandi, F; Sargent, RL | 1 |
| Jang, JH; Jung, CW; Jung, HA; Kim, K; Kim, SJ; Maeng, CH; Park, S | 1 |
| Jin, Z; Lin, G; Liu, L; Ma, A; Si, Y; Sun, Y; Wang, L; Wu, D; Zhang, X; Zhang, Y; Zhao, G | 1 |
| Cui, J; Guo, R; Hoffman, AR; Hu, JF; Li, W; Sun, J; Wang, G; Wang, H | 1 |
| Chen, J; Chen, L; Gao, L; Gong, S; Hu, X; Liu, M; Lu, S; Ni, X; Qiu, H; Song, X; Wang, J; Wang, L; Xu, S; Xu, X; Yang, J; Zhang, W | 1 |
| Borthakur, G; Brandt, M; Cortes, J; Daver, N; Garcia-Manero, G; Jabbour, E; Kadia, T; Kantarjian, H; Patel, K; Pemmaraju, N; Pierce, S; Ravandi, F; Wang, X | 1 |
| Abla, O; Adachi, S; Auvrignon, A; Beverloo, HB; Chang, TT; Creutzig, U; de Bont, E; De Moerloose, B; Dworzak, M; Elitzur, S; Forestier, E; Fynn, A; Hasle, H; Inaba, H; Lee, V; Liang, DC; Locatelli, F; Masetti, R; Raimondi, SC; Reinhardt, D; Rodriguez, L; Shen, S; Taga, T; Tomizawa, D; Van Roy, N; Yeoh, AE; Zhou, Y; Zimmermann, M | 1 |
| Dou, MH; Hu, C; Huang, J; Jin, J; Li, Y; Lou, YJ; Luo, YW; Ma, LY; Mao, LP; Mei, C; Niu, LM; Ren, YL; Tong, HY; Wang, JH; Wei, JY; Xie, LL; Xu, GX; Ye, L; Ye, XN; Yu, WJ; Zhou, XP | 1 |
| Ai, H; Fan, R; Fu, Y; Hu, J; Liu, S; Mi, R; Song, Y; Wang, P; Wang, X; Wei, X; Yin, Q; Zhou, J; Zhu, X | 1 |
| Alonzo, T; Auvrignon, A; Balwierz, W; Beverloo, HB; Bongers, M; Cloos, J; Creutzig, U; De Moerloose, B; Dworzak, M; Forestier, E; Fynn, A; Gibson, B; Harrison, CJ; Hirsch, B; Johnston, D; Kaspers, G; Klein, K; Lee, V; Pession, A; Popa, A; Raimondi, S; Reedijk, A; Reinhardt, D; Rubnitz, J; Salgado, C; Taga, T; Tawa, A; Zapotocky, M; Zeller, B; Zimmerman, M | 1 |
| Bhatnagar, B; Blum, W; Canning, R; Devine, SM; Garzon, R; Geyer, S; Klisovic, R; Marcucci, G; Vasu, S; Walker, AR; Walsh, K; Wang, H; Wu, YZ | 1 |
| Beltrão, EI; Benicio, MT; Bezerra, MA; Bezerra, MF; Coelho-Silva, JL; Lucena-Araujo, AR; Machado, CG; Nascimento, JC; Rego, EM; Rocha, CR | 1 |
| Borthakur, G; Estrov, Z; Faderl, S; Ferrajoli, A; Garcia-Manero, G; Huang, X; Kantarjian, HM; Kwari, M; Ravandi, F; Thomas, DA; Verstovsek, S | 1 |
| Forestier, E; Frost, BM; Jonsson, OG; Kanerva, J; Larsson, R; Lönnerholm, G; Nordgren, A; Nygaard, R; Schmiegelow, K | 1 |
| Advani, A; Kalaycio, M; Pohlman, B; Rybicki, L; Sekeres, M; Sobecks, R; Tripp, B | 1 |
| Jones, RL; Kulkarni, S; Mehta, J; Morgan, G; Potter, M; Powles, R; Saso, R; Singhal, S; Sirohi, B; Smith, K; Swansbury, GJ; Treleaven, J | 1 |
| Choudhury, RC; Palo, AK; Sahoo, D | 1 |
| Li, Y; Mi, Y; Qiu, L; Wang, J; Zhao, Y; Zou, D | 1 |
| Bian, S; Fu, M; Lin, D; Liu, J; Mi, Y; Wang, J; Wang, Y; Yu, W | 1 |
| Hu, NP; Hu, XM; Li, L; Liu, C; Liu, F; Ma, R; Wang, HZ; Xiao, HY; Xu, YG; Yang, XH; Zhang, SS; Zheng, CM | 1 |
| Wakita, A | 1 |
| Borthakur, G; Estey, EE | 1 |
| Betts, DR; Bourquin, JP; Bradtke, J; Creutzig, U; Dworzak, MN; Haas, OA; Reinhardt, D; Sander, A; Stary, J; von Neuhoff, C; Zemanova, Z; Zimmermann, M | 1 |
| Bocchia, M; Crupi, R; Defina, M; Gozzetti, A; Lauria, F; Pietrini, A; Raspadori, D; Rondoni, M | 1 |
| Fong, C; Tong, M | 1 |
| Celentano, M; Criscuolo, C; Ferrara, F; Izzo, T; Mele, G; Riccardi, C | 1 |
| Hamamoto, K; Hanada, R; Horibe, K; Imaizumi, M; Kigasawa, H; Kobayashi, R; Kudo, K; Morimoto, A; Nakayama, H; Tabuchi, K; Tawa, A; Tsuchida, M; Tsuchiya, S; Tsukimoto, I; Yabe, H | 1 |
| Choi, Y; Jeon, M; Kang, YA; Kim, DY; Kim, SD; Lee, JH; Lee, KH; Lee, YJ; Lee, YS; Seol, M; Sym, SJ; Yun, SC | 1 |
| Artz, A; Campbell, NP; Daugherty, C; Gajria, D; Godley, LA; Green, M; Gurbuxani, S; Huo, D; Hyjek, E; Larson, RA; Larson, SM; Odenike, O; Sipkins, D; Stock, W; Thirman, M; Van Besien, K; Weiner, H; Zhang, Y | 1 |
| Bornhäuser, M; Ehninger, G; Hasford, J; Kramer, M; Pfirrmann, M; Röllig, C; Schaich, M; Thiede, C | 1 |
| Atkinson, HD; Colovic, M; Colovic, N; Jankovic, G; Kraguljac, N; Radojkovic, M; Stanisavljevic, D; Suvajdzic, N; Tomin, D; Vidovic, A | 1 |
| Ritchie, EK | 1 |
| Creutzig, U; Reinhardt, D; Sander, A; Von Neuhoff, C | 1 |
| de la Torre, C; Pincheira, J; Rodríguez, N; Valenzuela, CY | 1 |
| Bahng, HS; Jang, GD; Jeong, YH; Ji, HS; Kim, EK; Kim, SH; Kim, SW; Kim, WK; Lee, JS; Park, CJ; Park, IG; Suh, CW; Suh, EJ | 1 |
| Creutzig, U; Hählen, K; Harbott, J; Huismans, DR; Kaspers, GJ; Pieters, R; Slater, RM; Veerman, AJ; Zimmermann, M; Zwaan, CM | 1 |
| Amess, JA; Bradburn, M; Carter, M; Dalley, CD; Lillington, DL; Lister, TA; Rohatiner, AZ | 1 |
| Dewald, GW; Lesser, ML; Silver, RT; Sison, CP | 1 |
| Arthur, DC; Bloomfield, CD; Byrd, JC; Carroll, AJ; Davey, FR; Dodge, RK; Edwards, CG; Feldman, EJ; Koduru, PR; Larson, RA; Mayer, RJ; Moore, JO; Mrózek, K; Patil, SR; Pettenati, MJ; Rao, KW; Schiffer, CA; Stone, RM; Watson, MS | 1 |
| Ravindranath, Y | 1 |
| Abgrall, JF; Berthou, C; Braekeleer, MD; Bris, MJ; Calvez, GL; Herry, A; Marion, V; Morel, F | 1 |
| Baer, MR; Barcos, M; Blumenson, L; Ferrone, S; Ford, LA; McElwain, BK; Mortazavi, A; Slack, JL; Stewart, CC; Wetzler, M | 1 |
| Okamoto, Y; Pui, CH; Razzouk, BI; Ribeiro, RC; Shenep, JL; Srivastava, DK | 1 |
| Abboud, CN; Bennett, JM; Dewald, G; Friedenberg, W; Hayes, FA; Liesveld, JL; Makary, AZ; Neuberg, D; Paietta, E; Rowe, JM; Tallman, MS; Wiernik, PH | 1 |
| Abhyankar, D; Advani, S; Amare Kadam, P; Baisane, C; Bakshi, C; Banavali, S | 1 |
| Brien, B; Chang, H; Minden, MD; Patterson, B; Salma, F; Yi, QL | 1 |
| Graf, M; Hecht, K; Nuessler, V; Pelka-Fleischer, R; Pfister, K; Reif, S; Schmetzer, H | 1 |
| Bassi, L; Carloni, M; Fonti, E; Meschini, R; Palitti, F | 1 |
| Auvrignon, A; Baruchel, A; Couillaud, G; Dalle, JH; Gandemer, V; Lamagnere, JP; Leblanc, T; Leverger, G; Mèchinaud, F; Michel, G; Pautard, B; Perel, Y; Piguet, Ch; Schmitt, C; Vannier, JP | 1 |
| Goldschmidt, N; Gural, A; Kornberg, A; Paltiel, O; Shopen, A; Spectre, G | 1 |
| Buesche, G; Buhr, T; Fonatsch, C; Freund, M; Ganser, A; Georgii, A; Hasford, J; Hecker, H; Hehlmann, R; Heimpel, H; Heinze, B; Holgado, S; Kreipe, HH; Pfirrmann, M; Schmeil, A; Tobler, A | 1 |
| Chau, WK; Chen, CC; Gau, JP; Ho, CH; Hsu, HC; Kwang, WK; Lee, KD; Tzeng, CH; Yang, CF; Yang, MH; You, JY; Yu, YB | 1 |
| Azuma, A; Chubb, S; Guo, Y; Hittelman, W; Huang, P; Jiang, Y; Li, Y; Liu, X; Matsuda, A; Plunkett, W | 1 |
| Bloomfield, CD; Carroll, AJ; Edwards, CG; Kolitz, JE; Larson, RA; Maharry, K; Marcucci, G; Mayer, RJ; Moore, JO; Mrózek, K; Pettenati, MJ; Powell, BL; Ruppert, AS; Schiffer, CA; Sterling, LJ; Vardiman, JW | 1 |
| Hassan, HT; Lu, C | 1 |
| Bloomfield, CD | 1 |
| Donelli, A; Ferrari, A; Giacobbi, F; Imovilli, A; Luppi, M; Morselli, M; Narni, F; Potenza, L; Riva, G; Temperani, P; Torelli, G | 1 |
| Beran, M; Cortes, J; Estrov, Z; Faderl, S; Ferrajoli, A; Garcia-Manero, G; Giles, FJ; Kantarjian, HM; Koller, C; Kwari, M; O'Brien, S; Ravandi, F; Verstovsek, S; Wierda, W | 1 |
| Bouabdallah, K; Daskalakis, M; Johansson, B; Kunzmann, R; Lübbert, M; Mauritzson, N; Müller-Berndorff, H; Onida, F; Schmitt-Gräff, A | 1 |
| Azma, RZ; Cheong, SK; Leong, CF; Salwati, S; Sharifah, NA | 1 |
| Califano, C; Celentano, M; D'Amico, MR; D'Arco, AM; Ferrara, F; Mele, G; Palmieri, S; Pollio, F | 1 |
| Angeli, JP; Bellini, MF; Ribeiro, LR | 1 |
| Hirokawa, M; Horiuchi, T; Kameoka, J; Miura, I; Miyamura, K; Nomura, J; Okuda, M; Sasaki, T; Sawada, K | 1 |
| Barnett, MJ; Bruyere, H; Dalal, BI | 1 |
| Kishi, K; Sekizawa, K; Suzuki, T | 1 |
| Arana-Yi, C; Baer, MR; Barcos, M; Block, AW; Ford, LA; Sait, SN | 1 |
| Bengtzen, S; Concha, H; Lehmann, S; Merup, M; Möllgård, L; Nahi, H; Paul, C; Selivanova, G; Svensson, A; Wiman, KG | 1 |
| Araújo, AG; dos Santos, GA; Falcão, RP; Garcia, AB; Jácomo, RH; Lima, AS; Lucena-Araujo, AR; Panepucci, RA; Rego, EM; Santana-Lemos, BA | 1 |
| Natarajan, AT; Obe, G | 1 |
| Hittelman, WN; Sen, P | 1 |
| Preston, RJ | 4 |
| Haren, JM; Kaneko, Y; Larson, RA; Rowley, JD; Variakojis, D | 1 |
| Hittelman, WN; Pollard, M | 1 |
| Coton, C; Fabry, L | 2 |
| Arimori, S; Nagao, T | 1 |
| Andersson, HC; Kihlman, BA | 2 |
| Cassileth, PA | 1 |
| Hayashi, M; Ishidate, M; Sofuni, T | 1 |
| Schwartz, JL; Weichselbaum, RR | 1 |
| Kalweit, S; Obe, G | 1 |
| Bryant, PE; Iliakis, G | 1 |
| Kubota, K; Mizoguchi, H; Nomura, Y; Okada, M | 1 |
| Amenomori, T; Ikeda, S; Kuriyama, K; Matuo, T; Nishino, K; Nonaka, H; Shibata, J; Suzuyama, J; Tagawa, M; Tomonaga, M | 1 |
| Becher, R; Gibas, Z; Sandberg, AA | 1 |
| Gustavsson, A; Mitelman, F; Olofsson, T; Olsson, I | 1 |
| Dohy, H; Kamada, N; Kuramoto, A; Maehama, S; Mandai, K; Oguma, N; Tahara, E; Takimoto, Y; Tanaka, K | 1 |
| Cuttner, J; Dimitriu-Bona, A; Najfeld, V; Seremetis, S; Winchester, RA | 1 |
| Fischer, P; Haas, O; Paietta, E; Schwarzmeier, JD | 1 |
| Gooch, PC; Preston, RJ | 1 |
| Gantt, R; Jones, GM; Parshad, R; Sanford, KK; Tarone, RE | 1 |
| Browman, G; Early, AP; Marinello, MJ; Preisler, HD; Raza, A; Stein, AM; Vlahides, G | 1 |
| Adamson, JW; Arlin, ZA; Clarkson, BD; Fialkow, PJ; Kempin, SJ; Najfeld, V; Singer, JW | 1 |
| Cooperman, BS; Klinger, HP | 1 |
| Jackson, CW; Murphy, S; Price, R; Pui, CH; Scarborough, V; Williams, DL | 1 |
| Fornace, AJ; Seres, DS | 1 |
| Barbărasă, C; Luca, D; Postică, F | 1 |
| Cooper, IA; Woodcock, DM | 1 |
| Moore, RC | 1 |
| Dardenne, M; de Witte, T; Fenaux, P; Hayat, M; Jaksic, B; Peetermans, M; Selleslag, D; Strijckmans, P; Suciu, S; Zittoun, R | 1 |
| Kozuka, H; Miyahara, T; Sakaguchi, M; Yamada, H | 1 |
| Andreeff, M; Beran, M; Escudier, S; Estey, E; Kantarjian, H; Koller, C; Kornblau, S; O'Brien, S; Pierce, S; Robertson, L | 1 |
| Archimbaud, E; Charrin, C; Fiere, D; Magaud, JP; Thomas, X | 1 |
| Hagemeijer, A; Hoebee, B; Honders, MW; Landegent, JE; Stegmann, AP; Willemze, R | 1 |
| Krishnaja, AP; Sharma, NK | 1 |
| Creutzig, U; Harbott, J; Löffler, H; Ludwig, WD; Riehm, H; Ritter, J; Schellong, G; Sperling, C; Zimmermann, M | 1 |
| Lehmann, AR; Parshad, R; Price, FM; Sanford, KK; Tarone, RE | 1 |
| Iliakis, G; Okayasu, R | 1 |
| Kishi, K; Sekizawa, K | 1 |
| Guilhot, F | 1 |
| Boogaerts, M; Bosly, A; Carli, MG; Castoldi, G; Cuneo, A; Demuynck, H; Doyen, C; Ferrant, A; Michaux, JL; Piva, N | 1 |
| Akatsuka, J; Furukawa, T; Nakazawa, S; Nishimura, K; Ohira, M; Okawa, Y; Sugita, K; Tsuchida, M | 1 |
| Fujita, H; Hirayama, M; Kohgo, Y; Kura, T; Mogi, Y; Nakaya, R; Niitsu, Y; Tsuji, N; Watanabe, N | 1 |
| Del Poeta, G; Delaroche, I; Masi, M; Nicoletti, B; Papa, G; Stasi, R; Tedeschi, B; Tribalto, M; Venditti, A; Vernole, P | 1 |
| Bauters, F; Detourmignies, L; Fenaux, P; Laï, JL; Wattel, E | 1 |
| Matsuda, Y; Tobari, I | 3 |
| Antoccia, A; Chessa, L; Ricordy, R; Tanzarella, C | 1 |
| Amabile, M; Arpinati, M; Farabegoli, P; Martinelli, G; Testoni, N; Tura, S; Visani, G; Zaccaria, A; Zinzani, PL; Zuffa, E | 1 |
| Asou, H; Awaya, N; Ikeda, Y; Kamada, N; Kawai, Y; Kizaki, M; Matsushita, H; Muto, A; Takayama, N; Ueno, H | 1 |
| Doi, T; Kobayashi, D; Koike, K; Kougo, Y; Matsunaga, T; Muramatsu, H; Niitsu, Y; Sakamaki, S; Sato, T; Watanabe, N | 1 |
| Belotti, D; Corneo, G; Maffè, PF; Pogliani, EM; Rivolta, GF | 1 |
| Kakihara, T; Kataoka, S; Kishi, K; Okada, R; Tanaka, A; Uchiyama, M; Watanabe, A; Yamamoto, K | 1 |
| Appelbaum, FR; Chen, IM; Godwin, J; Head, DR; Kopecky, KJ; Leith, CP; McConnell, T; Slovak, ML; Willman, CL | 1 |
| Arthur, DC; Bigner, S; Bloomfield, CD; Carroll, AJ; Davey, FR; Lawrence, D; Mayer, RJ; Mrózek, K; Pettenati, MJ; Rao, KW; Schiffer, CA; Slack, JL; Tantravahi, R | 1 |
| Bozsakyová, E; Chalupa, I; Farkasová, T; Gábelová, A; Horváthová, E; Ruzeková, L; Slamenová, D; Stĕtina, R | 1 |
| Duell, T; Gerhartz, HH; Mittermüller, J; Poleck, B; Schmetzer, HM; Wilmanns, W | 1 |
| Hall, JL; Hamblin, TJ; Myint, H; Ross, FM | 1 |
| Haase, D; Hiddemann, W; Schoch, C; Verbeek, W; Wörmann, B | 1 |
| Andreeff, M; Beran, M; Estey, EH; Kantarjian, HM; Keating, M; Kornblau, S; O'Brien, S; Pierce, S | 1 |
| de Nully Brown, P; Geisler, CH; Jurlander, J; Pedersen-Bjergaard, J; Victor, MA | 1 |
| Ottaviani, E; Pellacani, A; Testoni, N; Tosi, P; Tura, S; Visani, G | 1 |
| Armstrong, MJ; Bradt, CI; Galloway, SM; Greenwood, SK; Hill, RB; Hilliard, CA; Johnson, TE | 1 |
| Alessandrino, EP; Bernasconi, C; Bernasconi, P; Bonfichi, M; Brusamolino, E; Canevari, A; Castagnola, C; Castelli, G; Lazzarino, M; Pagnucco, G | 1 |
| Amigo, ML; del Cañizo, MC; Gonzalez, MB; Gutiérrez, N; Hernández, JM; Mateos, MV; San Miguel, JF | 1 |
| Bustillo, M; García-Torremocha, MS; Sastre, JL; Suárez-Gago, M; Ulibarrena, C; Vázquez, MO | 1 |
| Aricò, M; Basso, G; Biondi, A; Conter, V; De Rossi, G; Di Tullio, MT; Lo Nigro, L; Masera, G; Messina, C; Miniero, R; Mori, PG; Pession, A; Rizzari, C; Rondelli, R; Santoro, N; Silvestri, D; Tamaro, P; Testi, A; Valsecchi, MG | 1 |
| Parshad, R; Sanford, KK | 1 |
| Carbonell, E; Creus, A; Marcos, R; Puerto, S; Ramírez, MJ; Surrallés, J | 1 |
| Amess, J; Carter, M; Howe, K; Lister, TA; Rohatiner, AZ; Slater, S | 1 |
| Aul, C; Büchner, T; Fonatsch, C; Gassmann, W; Haase, D; Haferlach, T; Heinecke, A; Heyll, A; Hiddemann, W; Hossfeld, D; Lengfelder, E; Löffler, H; Ludwig, WD; Maschmeyer, G; Sauerland, MC; Schoch, C; Wörmann, B | 1 |
| Doerr, CL; Kligerman, AD; Tennant, AH | 1 |
| Abgrall, JP; Brice, P; Brion, A; Caillot, D; Cordonnier, C; Desablens, B; Dreyfus, F; Fenaux, P; Gratecos, N; Guerci, A; Hecquet, B; Hoang-Ngoc, L; Ifrah, N; Janvier, M; Leporrier, M; Lioure, B; Milpied, N; Pignon, B; Rochant, H; Sadoun, A; Solary, E; Stoppa, AM; Tilly, H; Veil, A; Wattel, E | 1 |
| Allio, T; Donner, EM; Preston, RJ | 1 |
| Arber, D; Dagis, A; Forman, SJ; Margolin, KA; Nademanee, A; Niland, J; O'Donnell, MR; Parker, PM; Schmidt, GM; Slovak, ML; Smith, EP; Snyder, DS; Somlo, G; Stein, AS | 1 |
| Camitta, B; Carroll, AJ; Chang, M; Gresik, MV; Raimondi, SC; Ravindranath, Y; Steuber, CP; Weinstein, H | 1 |
| Lorsbach, RB; Mathew, S; Raimondi, SC; Sandlund, JT; Shearer, P | 1 |
| Bennett, JM; Cassileth, PA; Dewald, G; Francois, CJ; Neuberg, D; Oken, MM; Paietta, E; Rowe, JM; Tallman, MS; Wiernik, PH | 1 |
| Appelbaum, FR; Cassileth, PA; Forman, SJ; Harrington, DH; Head, DR; Kopecky, KJ; Mohamed, A; Paietta, E; Rowe, JM; Slovak, ML; Theil, KS; Willman, CL | 1 |
| Duesberg, P; Hehlmann, R; Stindl, R | 1 |
| Bordessoule, D; Castaigne, S; Chevret, S; Chomienne, C; Cony Makhoul , P; De Botton , S; Deconinck, E; Degos, L; Desablens, B; Dombret, H; Fegueux, N; Fenaux, P; Fey, M; Gardin, C; Geiser, K; Guerci, A; Hess, U; Huguet, F; Link, H; Maloisel, F; Preudhomme, C; Rayon, C; San Miguel , J; Sanz, M; Solary, E; Sotto, JJ; Stamatoullas, A; Thomas, X; Travade, P | 1 |
| Büchner, T; Fonatsch, C; Haase, D; Haferlach, T; Heinecke, A; Hiddemann, W; Löffler, H; Sauerland, MC; Schlegelberger, B; Schoch, C; Staib, P | 1 |
| Eden, O; Gibson, B; Hann, I; Harrison, C; Harrison, G; Hill, F; Richards, S; Vora, A | 1 |
| Cuneo, A; Liso, V; Mestice, A; Pannunzio, A; Rocchi, M; Specchia, G; Storlazzi, CT; Surace, C | 1 |
| Bernasconi, P; Boni, M; Castoldi, GL; Ciolli, S; Clavio, M; Cox, MC; Cuneo, A; Del Poeta, G; Dini, D; Falzetti, D; Fanin, R; Gobbi, M; Isidori, A; Leoni, F; Liso, V; Malagola, M; Mandelli, F; Martinelli, G; Mecucci, C; Petti, MC; Piccaluga, PP; Rondelli, R; Russo, D; Sessarego, M; Specchia, G; Testoni, N; Torelli, G; Tura, S; Visani, G | 1 |
| Ahmed, T; Feldman, EJ; Kancherla, R; Liu, D; Papageorgio, C; Pozzuoli, M; Seiter, K; Sreekantaiah, C; Weisberger, J; Weiss, M | 1 |
| Calasanz, MJ; Gesk, S; Grote, W; Harder, L; Martín-Subero, JI; Novo, FJ; Schlegelberger, B; Schoch, R; Siebert, R | 1 |
| Burnett, AK; Chatters, S; Goldstone, AH; Grimwade, D; Harrison, CJ; Harrison, G; Oliver, F; Walker, H; Wheatley, K | 1 |
| Aoki, S; Imai, K; Kazama, Y; Shimizu, H; Takahashi, T; Tsujisaki, M; Yoshimoto, M | 1 |
| Adachi, S; Akiyama, Y; Hamahata, K; Kubota, M; Lin, YW; Nakahata, T; Watanabe, K | 1 |
| Aivado, M; Aul, C; Germing, U; Giagounidis, AA; Heinsch, M; Hildebrandt, B | 1 |
| Fiore, M; Mosesso, P; Palitti, F; Penna, S; Schinoppi, A; Schmitz, C; Schuber, M; Seibt, D | 1 |
| Benova, D; Boulanova, M; Darroudi, F; Georgieva, I; Georgieva, R; Grigorova, M; Hadjidekova, V; Hristova, R; Natarajan, AT; Nikolova, T; Nilsson, R; Panev, T; Popov, T | 1 |
| Delgado, J; Garcia-Grande, A; Hernandez-Navarro, F; Jimenez, MC; Morado, M | 1 |
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| Abella, E; Alvarado, CS; Chauvenet, A; Dubowy, R; Harris, M; Inoue, S; Krischer, JP; Ravindranath, Y; Ritchey, AK; Wiley, J | 1 |
| Forsblom, AM; Gahrton, G; Hellström-Lindberg, E; Kock, Y; Lindberg, G; Ost, A; Robèrt, KH | 1 |
| Belin, T; Champlin, R; Gajewski, J; Lee, M; Nimer, S; Schiller, G; Territo, M | 1 |
| Christodoulidou, F; Macera, MJ; Silver, RT; Verma, RS | 1 |
| Elliott, S; Marlton, P; Meagher, D; Rodwell, R; Taylor, D; Taylor, K; Timms, P; White, S; Wiley, J; Wright, S | 1 |
| Challinor, P; Ng, JP; Strevens, MJ | 1 |
| Jäger, U; Köller, U; Koller-Weber, E; Marosi, C; Nowotny, H; Pirc-Danoewinata, H; Schneider, B; Schwarzinger, I; Steger, G; Vahls, P | 1 |
| Köberle, B; Speit, G | 1 |
| Payne, HS; Preston, GA; Preston, RJ | 1 |
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| Goto, S; Hotta, T; Ichihara, M; Ichikawa, A; Kagami, Y; Murate, T; Ohashi, H; Takagi, N; Tsushita, K; Yamao, H | 1 |
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| Capizzi, RL | 1 |
| Arentsen-Honders, MW; Arkesteijn, GJ; Colly, LP; Kerster, MG; Richel, DJ; ter Riet, PM; Willemze, R | 1 |
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| Holmberg, M | 1 |
| Daeschner, CW; Heath, DV; Lockhart, LH; McCombs, JL; Rouse, BM | 1 |
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| Cortés, F; Mateos, S; Ortiz, T; Piñero, J | 2 |
| Maemori, M; Matsuda, Y; Tobari, I | 1 |
| Abe, T; Fujii, H; Horiike, S; Inazawa, J; Misawa, S; Nakagawa, H; Sonoda, Y; Tanaka, S; Taniwaki, M; Tsuda, S | 1 |
| Bryant, PE; Mozdarani, H | 1 |
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| Arthur, DC; Brunning, RD; Michels, SD; Robison, LL; Saumur, J | 1 |
| Miyazaki, T; Morioka, M; Sakurada, K | 1 |
| Burns, CP; Lazarus, HM; Vogler, WR; Winton, EF | 1 |
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| Deknudt, G; Kalina, I; Léonard, A | 1 |
| Levy, JM; Lutz, P; Seiller, F; Stoll, C | 1 |
| Daly, KM; Larson, RA; Le Beau, MM; Pape, LH; Rowley, JD; Vardiman, JW; Wernli, M | 1 |
| Abe, T; Kobayashi, T; Kondo, I; Sato, Y; Tomiyama, J; Yoda, Y | 1 |
| Cantù-Rajnoldi, A; Conter, V; Creutzig, U; Masera, G; Odenwald, E; Riehm, H; Ritter, J; Romitti, L | 1 |
| Aardema, MJ; Preston, RJ | 1 |
| Abe, T; Kamakura, M; Kida, M; Kinoshita, T; Konno, S; Ryu, T; Uehara, M | 1 |
| Fekete, S; Ihle, R; Kasparu, H; Köller, U; Krieger, O; Lutz, D; Minigo, H; Nowotny, H; Tüchler, H | 1 |
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| Darroudi, F; Meijers, M; Mullenders, LH; Natarajan, AT | 1 |
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21 review(s) available for cytarabine and Abnormalities, Autosome
| Article | Year |
|---|---|
Diagnosis and Treatment of Patients With Acute Myeloid Leukemia With Myelodysplasia-Related Changes (AML-MRC).
Topics: Aged; Aminopyridines; Antineoplastic Agents; Blood Cells; Bone Marrow; Bone Marrow Examination; Chromosome Aberrations; Cytarabine; Cytogenetic Analysis; Daunorubicin; DNA Mutational Analysis; Genetic Predisposition to Disease; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Prognosis; PubMed; Triazines | 2020 |
Do cytogenetics affect the post-remission strategy for older patients with AML in CR1?
Topics: Aged; Aged, 80 and over; Chromosome Aberrations; Cytarabine; Cytogenetic Analysis; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction | 2017 |
How I treat older patients with acute myeloid leukemia.
Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Chromosome Aberrations; Cytarabine; Decitabine; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Hematopoietic Stem Cell Transplantation; Histone Deacetylase Inhibitors; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Prognosis; Remission Induction; Survival Rate; Transplantation, Homologous | 2018 |
[Characteristics of elderly patients with acute myelogenous leukemia].
Topics: Age Distribution; Aged; Aged, 80 and over; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cytarabine; Hospitals, Municipal; Humans; Japan; Leukemia, Myeloid, Acute; Remission Induction; Spouses | 2009 |
Therapy of acute myelogenous leukemia in adults.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Clinical Trials as Topic; Combined Modality Therapy; Core Binding Factors; Cytarabine; Daunorubicin; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Middle Aged; Neoplasm Proteins; Neoplasm, Residual; Prognosis; Remission Induction; Risk; Salvage Therapy; Treatment Outcome | 2010 |
Safety and efficacy of azacitidine in the treatment of elderly patients with myelodysplastic syndrome.
Topics: Age Factors; Aged; Antimetabolites, Antineoplastic; Azacitidine; Chromosome Aberrations; Cytarabine; Disease Progression; Drug Evaluation; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Outcome Assessment, Health Care; Quality of Life; Risk Assessment; Sickness Impact Profile | 2012 |
Recent advances in pediatric acute lymphoblastic and myeloid leukemia.
Topics: Acute Disease; Antineoplastic Agents; Biomarkers, Tumor; Child; Chromosome Aberrations; Clinical Trials as Topic; Cytarabine; Disease-Free Survival; Humans; Leukemia, Myeloid; Mitoxantrone; Neoplasm, Residual; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2003 |
Viridans streptococcal sepsis: clinical features and complications in childhood acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Chromosome Aberrations; Combined Modality Therapy; Cytarabine; Daunorubicin; Deoxyadenosines; Double-Blind Method; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Hypotension; Immunocompromised Host; Leukemia, Myeloid; Male; Mycoses; Neutropenia; Randomized Controlled Trials as Topic; Respiratory Distress Syndrome; Retrospective Studies; Sepsis; Streptococcal Infections; Viridans Streptococci | 2003 |
Treatment intensity significantly influencing fibrosis in bone marrow independently of the cytogenetic response: meta-analysis of the long-term results from two prospective controlled trials on chronic myeloid leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bone Marrow; Chromosome Aberrations; Controlled Clinical Trials as Topic; Cytarabine; Cytogenetic Analysis; Disease Progression; Drug Resistance, Neoplasm; Female; Humans; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Primary Myelofibrosis; Prospective Studies; Risk Factors; Survival Rate | 2004 |
Adult acute nonlymphocytic leukemia.
Topics: Acute Disease; Adult; Aged; Antigens, Neoplasm; Antigens, Surface; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cytarabine; Daunorubicin; Humans; Leukemia; Meningeal Neoplasms; Methotrexate; Middle Aged; Thioguanine | 1984 |
[Chromosome analysis and TdT determination: important prognostic parameters of blastic crises in chronic myelocytic leukemia].
Topics: Busulfan; Chromosome Aberrations; Cytarabine; DNA Nucleotidylexotransferase; DNA Nucleotidyltransferases; Humans; Hydroxyurea; Karyotyping; Leukemia, Myeloid; Prednisone; Prognosis; Thioguanine; Vincristine | 1982 |
Clinical review on features and cytogenetic patterns in adult acute myeloid leukemia with lymphoid markers.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aneuploidy; Antigens, CD; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Chromosome Aberrations; Cytarabine; DNA Nucleotidylexotransferase; Etoposide; Female; Gene Rearrangement; Humans; Immunophenotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Proteins; Neoplastic Stem Cells; Philadelphia Chromosome; Remission Induction; Vindesine | 1993 |
The prognostic value of cytogenetics is reinforced by the kind of induction/consolidation therapy in influencing the outcome of acute myeloid leukemia--analysis of 848 patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosome Deletion; Chromosome Inversion; Chromosomes, Human; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Hepatomegaly; Humans; Idarubicin; Karyotyping; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Prognosis; Remission Induction; Retrospective Studies; Splenomegaly; Survival Analysis; Translocation, Genetic; Treatment Outcome | 2001 |
Secondary acute myelogenous leukemia and myelodysplasia without abnormalities of chromosome 11q23 following treatment of acute leukemia with topoisomerase II-based chemotherapy.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosomes, Human, Pair 11; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cytarabine; Disease Progression; Disease-Free Survival; Enzyme Inhibitors; Etoposide; Female; Humans; Idarubicin; Incidence; Karyotyping; Leukemia, Myeloid; Life Tables; Male; Middle Aged; Mitoxantrone; Myelodysplastic Syndromes; Neoplasm Proteins; Neoplasms, Second Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Randomized Controlled Trials as Topic; Remission Induction; Retrospective Studies; Topoisomerase II Inhibitors; Treatment Outcome; Tretinoin | 2001 |
Control of nuclear division and chromosomal abnormalities in cytochalasin B-treated normal and transformed cells.
Topics: Cell Division; Cell Nucleus; Cell Transformation, Neoplastic; Cell Transformation, Viral; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Cytochalasin B; DNA; DNA Replication | 1978 |
Mutagenic clastogenic and oncogenic effects of 1-beta-D-arabinofuranosylcytosine.
Topics: Animals; Carcinogens; Cell Cycle; Cell Differentiation; Cell Line; Chromosome Aberrations; Cricetinae; Crossing Over, Genetic; Cytarabine; DNA; Guinea Pigs; Humans; Mice; Mutagens; Rats; Teratogens | 1979 |
Leukemia: experimental and preclinical studies.
Topics: Alkylating Agents; Animals; Antibiotics, Antineoplastic; Cell Line; Chromosome Aberrations; Cytarabine; Drug Resistance; Humans; Leukemia; Methotrexate; Prognosis | 1990 |
Leukemic cell maturation.
Topics: Cell Differentiation; Cell Line; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Dimethyl Sulfoxide; Genotype; Hematopoietic Stem Cells; Humans; Leukemia; Leukemia, Myeloid, Acute; Neoplastic Stem Cells; Neutrophils; Oncogenes; Phenotype; Tetradecanoylphorbol Acetate; Vitamin A | 1985 |
Acute nonlymphocytic leukemia.
Topics: Adolescent; Adult; Antigens, Surface; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Chromosome Aberrations; Cytarabine; Doxorubicin; Hematopoietic Stem Cells; Humans; Leukemia; Leukemia, Myeloid, Acute; Nervous System Neoplasms; Prednisolone; Prognosis; Recurrence; Risk; Vincristine | 1985 |
Mechanisms of chromosomal aberration production. 3. Chemicals and ionizing radiation.
Topics: Alkylating Agents; Animals; Caffeine; Chromosome Aberrations; Cyanides; Cytarabine; Deoxyadenosines; DNA; DNA Repair; DNA Replication; DNA, Single-Stranded; Floxuridine; Hydroxyurea; Mitosis; Models, Biological; Mutagens; Radiation Genetics; Recombination, Genetic; Streptonigrin; Theobromine; Theophylline | 1974 |
[Cytogenetic changes associated with cellular infection with herpes simplex virus].
Topics: Animals; Cell Line; Cells, Cultured; Chromosome Aberrations; Cricetinae; Cytarabine; Cytogenetics; Cytopathogenic Effect, Viral; Dactinomycin; HeLa Cells; Herpes Simplex; Kidney; Leukocytes; Lung; Puromycin; Simplexvirus; Virus Cultivation | 1973 |
31 trial(s) available for cytarabine and Abnormalities, Autosome
| Article | Year |
|---|---|
Autologous hematopoietic cell transplantation following high-dose cytarabine consolidation for core-binding factor-acute myeloid leukemia in first complete remission: a phase 2 prospective trial.
Topics: Adult; Autografts; Chromosome Aberrations; Chromosomes, Human; Consolidation Chemotherapy; Core Binding Factors; Cytarabine; Disease-Free Survival; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Proteins; Remission Induction; Survival Rate | 2021 |
Prognostic significance of the Medical Research Council cytogenetic classification compared with the European LeukaemiaNet risk classification system in acute myeloid leukaemia.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cytarabine; Databases, Factual; Disease-Free Survival; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Risk Assessment; Survival Rate; United Kingdom | 2015 |
A randomized study of clofarabine versus clofarabine plus low-dose cytarabine as front-line therapy for patients aged 60 years and older with acute myeloid leukemia and high-risk myelodysplastic syndrome.
Topics: Adenine Nucleotides; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Chromosome Aberrations; Clofarabine; Cytarabine; Disease-Free Survival; Drug Administration Schedule; Female; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Myelodysplastic Syndromes; Survival Rate | 2008 |
Timed sequential induction chemotherapy and risk-adapted postremission therapy for acute myelogenous leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cohort Studies; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Drug Administration Schedule; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Remission Induction | 2008 |
Outcome of high-dose cytarabine-based induction therapy followed by hematopoietic stem cell transplantation in acute myeloid leukemia: influence of karyotype.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cytarabine; Etoposide; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Karyotyping; Leukemia, Myeloid, Acute; Middle Aged; Remission Induction; Survival Rate; Treatment Outcome | 2008 |
Effect and prognostic analysis of treatment for acute myeloid leukemia using Chinese drugs combined with chemotherapy.
Topics: Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Child; Chromosome Aberrations; Cytarabine; Daunorubicin; Drugs, Chinese Herbal; Etoposide; Female; Humans; Immunophenotyping; Integrative Medicine; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Prognosis; Treatment Outcome; Young Adult | 2009 |
Prognostic impact of specific chromosomal aberrations in a large group of pediatric patients with acute myeloid leukemia treated uniformly according to trial AML-BFM 98.
Topics: Adolescent; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Chromosome Aberrations; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Combined Modality Therapy; Confidence Intervals; Cytarabine; Cytogenetic Analysis; Disease-Free Survival; Etoposide; Female; Follow-Up Studies; Humans; Idarubicin; In Situ Hybridization, Fluorescence; Leukemia, Myeloid, Acute; Male; Probability; Proportional Hazards Models; Radiotherapy, Adjuvant; Reverse Transcriptase Polymerase Chain Reaction; Risk Assessment; Severity of Illness Index; Statistics, Nonparametric; Stem Cell Transplantation; Survival Analysis; Transplantation, Homologous; Treatment Outcome | 2010 |
Prospective study of a therapeutic regimen with all-trans retinoic acid and anthracyclines in combination of cytarabine in children with acute promyelocytic leukaemia: the Japanese childhood acute myeloid leukaemia cooperative study.
Topics: Adolescent; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Chromosome Aberrations; Cytarabine; Epidemiologic Methods; Female; Humans; Infant; Leukemia, Promyelocytic, Acute; Leukocyte Count; Male; Neoplasm, Residual; Neutropenia; Prognosis; Recurrence; Treatment Outcome; Tretinoin | 2011 |
Prediction of post-remission survival in acute myeloid leukaemia: a post-hoc analysis of the AML96 trial.
Topics: Adolescent; Adult; Age Factors; Antigens, CD34; Chromosome Aberrations; Cytarabine; Female; fms-Like Tyrosine Kinase 3; Hematopoietic Stem Cell Transplantation; Humans; Karyotype; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Survival Analysis; Transplantation, Homologous; Treatment Outcome | 2012 |
Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B (CALGB 8461).
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosome Inversion; Chromosomes, Human; Cytarabine; Daunorubicin; Disease-Free Survival; Follow-Up Studies; Humans; Incidence; Karyotyping; Leukemia, Myeloid; Life Tables; Prospective Studies; Recurrence; Remission Induction; Risk Factors; Survival Analysis; Translocation, Genetic; Treatment Outcome; Trisomy | 2002 |
A phase 3 study of three induction regimens and of priming with GM-CSF in older adults with acute myeloid leukemia: a trial by the Eastern Cooperative Oncology Group.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chronic Disease; Cytarabine; Cytogenetics; Disease-Free Survival; Drug Administration Schedule; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Male; Middle Aged; Recombinant Proteins; Survival Analysis; Time Factors | 2004 |
Maintenance therapy in childhood acute myeloid leukemia.
Topics: Acute Disease; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Child; Chromosome Aberrations; Cytarabine; Disease-Free Survival; Humans; Leukemia, Myeloid; Mercaptopurine; Mitoxantrone; Prognosis; Survival Analysis; Time Factors | 2004 |
Clofarabine and cytarabine combination as induction therapy for acute myeloid leukemia (AML) in patients 50 years of age or older.
Topics: Acute Disease; Adenine Nucleotides; Aged; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Chromosome Aberrations; Clofarabine; Cytarabine; Drug Administration Schedule; Humans; Leukemia, Myeloid; Middle Aged; Remission Induction; Survival Rate; Treatment Outcome | 2006 |
Intensive chemotherapy for poor prognosis myelodysplasia (MDS) and secondary acute myeloid leukemia (sAML) following MDS of more than 6 months duration. A pilot study by the Leukemia Cooperative Group of the European Organisation for Research and Treatmen
Topics: Adolescent; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Europe; Humans; Idarubicin; Length of Stay; Leukemia, Myeloid, Acute; Middle Aged; Myelodysplastic Syndromes; Neoplasms, Second Primary; Pilot Projects; Prognosis; Prospective Studies; Survival Analysis | 1995 |
Treatment of myelodysplastic syndromes with AML-type chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Karyotyping; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Prognosis; Remission Induction; Vidarabine | 1993 |
Clinical significance of surface antigen expression in children with acute myeloid leukemia: results of study AML-BFM-87.
Topics: Acute Disease; Adolescent; Antibodies, Monoclonal; Antigens, CD; Antigens, Neoplasm; Antigens, Surface; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Child; Child, Preschool; Chromosome Aberrations; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Humans; Immunophenotyping; Infant; Leukemia, Myeloid; Neoplastic Stem Cells; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Prospective Studies; Sensitivity and Specificity; Treatment Outcome | 1995 |
Interferon alfa and low-dose cytosine-arabinoside for the treatment of patients with chronic myelogenous leukemia in chronic phase. French CML Study Group.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Female; Humans; Interferon-alpha; Leukemia, Myeloid, Chronic-Phase; Male; Multicenter Studies as Topic; Pilot Projects; Randomized Controlled Trials as Topic | 1993 |
Anthracycline drugs and MDR expression in human leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Aberrations; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Idarubicin; Leukemia, Myeloid; Life Tables; Male; Middle Aged; Neoplasm Proteins; Neoplastic Stem Cells; Prognosis; Remission Induction; Survival Analysis; Treatment Outcome | 1996 |
Acute myeloid leukemia in the elderly: assessment of multidrug resistance (MDR1) and cytogenetics distinguishes biologic subgroups with remarkably distinct responses to standard chemotherapy. A Southwest Oncology Group study.
Topics: Age Factors; Aged; Aged, 80 and over; Antigens, CD; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Daunorubicin; Double-Blind Method; Drug Resistance, Multiple; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Neoplasms, Second Primary; Recombinant Proteins | 1997 |
Clonality analysis as a tool to study the biology and response to therapy in myelodysplastic syndromes.
Topics: Blotting, Southern; Chromosome Aberrations; Cytarabine; Disease-Free Survival; Female; Gene Rearrangement; Genetic Markers; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Myelodysplastic Syndromes; Probability; Prognosis; Recombinant Proteins; Survival Rate; Time Factors | 1997 |
Randomized clinical study comparing aggressive chemotherapy with or without G-CSF support for high-risk myelodysplastic syndromes or secondary acute myeloid leukaemia evolving from MDS.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cytarabine; Disease-Free Survival; Etoposide; Female; Follow-Up Studies; Gene Rearrangement; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Myelodysplastic Syndromes; Neutropenia; Recurrence; Survival Analysis; Treatment Outcome | 1998 |
Intensive BFM chemotherapy for childhood ALL: interim analysis of the AIEOP-ALL 91 study. Associazione Italiana Ematologia Oncologia Pediatrica.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Child; Child, Preschool; Chromosome Aberrations; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Disease-Free Survival; Doxorubicin; Female; Humans; Infant; Italy; Leucovorin; Male; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Remission Induction; Risk; Thioguanine; Treatment Outcome; Vincristine | 1998 |
Double induction strategy for acute myeloid leukemia: the effect of high-dose cytarabine with mitoxantrone instead of standard-dose cytarabine with daunorubicin and 6-thioguanine: a randomized trial by the German AML Cooperative Group.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cytarabine; Daunorubicin; Humans; Karyotyping; L-Lactate Dehydrogenase; Leukemia, Myeloid, Acute; Leukocyte Count; Middle Aged; Mitoxantrone; Prognosis; Remission Induction; Thioguanine; Treatment Outcome | 1999 |
Quinine improves results of intensive chemotherapy (IC) in myelodysplastic syndromes (MDS) expressing P-glycoprotein (PGP). Updated results of a randomized study. Groupe Français des Myélodysplasies (GFM) and Groupe GOELAMS.
Topics: Adult; Aged; Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Aberrations; Cytarabine; Disease Progression; Female; Genes, MDR; Humans; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Myelodysplastic Syndromes; Phenotype; Quinine; Remission Induction; Survival Analysis | 1999 |
Karyotypic analysis predicts outcome of preremission and postremission therapy in adult acute myeloid leukemia: a Southwest Oncology Group/Eastern Cooperative Oncology Group Study.
Topics: Acute Disease; Adolescent; Adult; Aneuploidy; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Chromosome Aberrations; Chromosomes, Human; Combined Modality Therapy; Cytarabine; Female; Humans; Idarubicin; Karyotyping; Leukemia, Myeloid; Life Tables; Male; Middle Aged; Remission Induction; Risk; Survival Analysis; Translocation, Genetic; Transplantation, Autologous; Transplantation, Homologous; Treatment Outcome | 2000 |
Additional chromosomal abnormalities in patients with acute promyelocytic leukaemia (APL) do not confer poor prognosis: results of APL 93 trial.
Topics: Adult; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosomes, Human, Pair 12; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 17; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 6; Chromosomes, Human, Pair 7; Chromosomes, Human, Pair 8; Chromosomes, Human, Pair 9; Cohort Studies; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Prognosis; Remission Induction; Survival Rate; Translocation, Genetic; Tretinoin; Trisomy | 2000 |
Patients with de novo acute myeloid leukaemia and complex karyotype aberrations show a poor prognosis despite intensive treatment: a study of 90 patients.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Chromosome Aberrations; Cytarabine; Cytogenetic Analysis; Daunorubicin; Disease-Free Survival; Female; Follow-Up Studies; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Prognosis; Remission Induction; Thioguanine | 2001 |
Determinants of outcome after intensified therapy of childhood lymphoblastic leukaemia: results from Medical Research Council United Kingdom acute lymphoblastic leukaemia XI protocol.
Topics: Adolescent; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Chromosome Aberrations; Chromosome Disorders; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Etoposide; Female; Humans; Infant; Leukocyte Count; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Remission Induction; Risk Factors; Sex Factors; Thioguanine; United Kingdom; Vincristine | 2001 |
The predictive value of hierarchical cytogenetic classification in older adults with acute myeloid leukemia (AML): analysis of 1065 patients entered into the United Kingdom Medical Research Council AML11 trial.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cyclophosphamide; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Administration Schedule; Etoposide; Female; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Humans; Immunologic Factors; Interferon-alpha; Karyotyping; Lenograstim; Leukemia, Myeloid; Life Tables; Male; Middle Aged; Predictive Value of Tests; Prednisone; Prognosis; Recombinant Proteins; Remission Induction; Survival Analysis; Thioguanine; Treatment Outcome; United Kingdom; Vincristine | 2001 |
Chronic myelogenous leukemia: a clinical and experimental evaluation of splenectomy and intensive chemotherapy.
Topics: Adult; Antineoplastic Agents; Busulfan; Chromosome Aberrations; Chromosomes, Human, 21-22 and Y; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Evaluation; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Humans; Hydroxyurea; Leukemia, Myeloid; Male; Middle Aged; Splenectomy; Thioguanine | 1975 |
Long-term outcome of high-dose cytarabine-based consolidation chemotherapy for adults with acute myelogenous leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Daunorubicin; Drug Administration Schedule; Etoposide; Female; Follow-Up Studies; Humans; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Survival Analysis; Time Factors | 1992 |
244 other study(ies) available for cytarabine and Abnormalities, Autosome
| Article | Year |
|---|---|
Decitabine combined with minimally myelosuppressive therapy for induction of remission in pediatric high-risk acute myeloid leukemia with chromosome 5q deletion: a report of three cases.
Topics: Abnormal Karyotype; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Chromosome Aberrations; Chromosome Deletion; Cytarabine; Decitabine; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Remission Induction | 2022 |
TGF-β1 and CXCL12 modulate proliferation and chemotherapy sensitivity of acute myeloid leukemia cells co-cultured with multipotent mesenchymal stromal cells.
Topics: Adult; Aged; Animals; Antimetabolites, Antineoplastic; Biomarkers; Bone Marrow; Bone Marrow Cells; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Chemokine CXCL12; Chromosome Aberrations; Coculture Techniques; Cytarabine; Drug Resistance, Neoplasm; Female; Humans; Immunophenotyping; Leukemia, Myeloid, Acute; Male; Mesenchymal Stem Cells; Mice; Middle Aged; Neoplasm Grading; Transforming Growth Factor beta1 | 2018 |
Targeting BRCA1/2 deficient ovarian cancer with CNDAC-based drug combinations.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; BRCA1 Protein; BRCA2 Protein; Cell Line, Tumor; Chromosome Aberrations; Cytarabine; DNA Damage; Drug Synergism; Female; Humans; Organoplatinum Compounds; Ovarian Neoplasms; Poly (ADP-Ribose) Polymerase-1; Tumor Stem Cell Assay | 2018 |
[Acute Lymphoblastic Leukemia - Diagnostics, Subgroups and Therapies].
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anthracyclines; Antineoplastic Agents; Asparaginase; Child; Child, Preschool; Chromosome Aberrations; Cyclophosphamide; Cytarabine; Dexamethasone; Female; Humans; Immunotherapy; Incidence; Infant; Male; Mercaptopurine; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Risk Factors; Vincristine; Young Adult | 2018 |
Sequential reduced-intensity chemotherapy for allogeneic hematopoietic stem cell transplantation in acute myeloid leukemia with rare cytogenetic abnormalities transformed from Fanconi anemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cytarabine; Fanconi Anemia; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Transplantation Conditioning; Transplantation, Homologous; Vidarabine | 2018 |
The combination of rituximab, bendamustine, and cytarabine for heavily pretreated relapsed/refractory cytogenetically high-risk patients with chronic lymphocytic leukemia.
Topics: Aged; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Chromosome Aberrations; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 17; Cytarabine; Cytogenetic Analysis; Drug Administration Schedule; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Neoplasm Staging; Nitrogen Mustard Compounds; Pilot Projects; Recurrence; Risk; Rituximab; Sequence Deletion; Survival Analysis | 2013 |
Core binding factor acute myeloid leukaemia and c-KIT mutations.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Chromosome Aberrations; Core Binding Factors; Cytarabine; Disease-Free Survival; Etoposide; Exons; Female; Humans; Idarubicin; L-Lactate Dehydrogenase; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Prognosis; Proto-Oncogene Proteins c-kit; Retrospective Studies; Stem Cell Transplantation; Young Adult | 2013 |
Identification of clinically important chromosomal aberrations in acute myeloid leukemia by array-based comparative genomic hybridization.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosome Deletion; Chromosomes, Human, Pair 17; Chromosomes, Human, Pair 5; Comparative Genomic Hybridization; Cytarabine; DNA Copy Number Variations; Drug Administration Schedule; Female; Humans; Idarubicin; Kaplan-Meier Estimate; Karyotype; Leukemia, Myeloid; Male; Middle Aged; Outcome Assessment, Health Care; Prognosis; Remission Induction | 2014 |
Prognostic factor analysis in core-binding factor-positive acute myeloid leukemia.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Core Binding Factors; Cytarabine; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Prognosis; Translocation, Genetic; Treatment Outcome; Young Adult | 2014 |
Increasing the dose of aclarubicin in low-dose cytarabine and aclarubicin in combination with granulocyte colony-stimulating factor (CAG regimen) can safely and effectively treat relapsed or refractory acute myeloid leukemia.
Topics: Aclarubicin; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Remission Induction; Treatment Outcome; Young Adult | 2014 |
An intragenic long noncoding RNA interacts epigenetically with the RUNX1 promoter and enhancer chromatin DNA in hematopoietic malignancies.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Chromatin; Chromosome Aberrations; Chromosomes; Core Binding Factor Alpha 2 Subunit; Cytarabine; DNA; Enhancer Elements, Genetic; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Exome; Gene Expression Regulation, Leukemic; HeLa Cells; Hematologic Neoplasms; Humans; K562 Cells; Leukemia, Myeloid, Acute; Mutation; Polycomb Repressive Complex 2; Promoter Regions, Genetic; RNA, Long Noncoding; Translocation, Genetic | 2014 |
High prognostic value of minimal residual disease detected by flow-cytometry-enhanced fluorescence in situ hybridization in core-binding factor acute myeloid leukemia (CBF-AML).
Topics: Adolescent; ADP-ribosyl Cyclase 1; Adult; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Cell Separation; Chromosome Aberrations; Consolidation Chemotherapy; Core Binding Factor Alpha 2 Subunit; Cytarabine; Daunorubicin; Female; Flow Cytometry; Humans; In Situ Hybridization, Fluorescence; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm, Residual; Neoplastic Stem Cells; Oncogene Proteins, Fusion; Prognosis; RUNX1 Translocation Partner 1 Protein; Young Adult | 2014 |
Heterogeneous cytogenetic subgroups and outcomes in childhood acute megakaryoblastic leukemia: a retrospective international study.
Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Child, Preschool; Chromosome Aberrations; Cytarabine; Disease-Free Survival; Female; Gene Rearrangement; Hematopoietic Stem Cell Transplantation; Humans; Infant; Kaplan-Meier Estimate; Karyotyping; Leukemia, Megakaryoblastic, Acute; Male; Prognosis; Retrospective Studies; Treatment Outcome | 2015 |
Epigenetic priming with decitabine followed by low-dose idarubicin/cytarabine has an increased anti-leukemic effect compared to traditional chemotherapy in high-risk myeloid neoplasms.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Chromosome Aberrations; Cytarabine; Decitabine; Disease Progression; Drug Administration Schedule; Drug Resistance, Neoplasm; Epigenesis, Genetic; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Myelodysplastic Syndromes; Recurrence; Remission Induction; Treatment Outcome | 2016 |
[Clinical features and survival analysis of patients with CD56 expression in de- novo acute myeloid leukemia with t（8;21）].
Topics: Bone Marrow; CD56 Antigen; Chromosome Aberrations; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Cytarabine; Disease-Free Survival; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Prognosis; Remission Induction; Retrospective Studies; Survival Analysis | 2015 |
Clinical Impact of Additional Cytogenetic Aberrations, cKIT and RAS Mutations, and Treatment Elements in Pediatric t(8;21)-AML: Results From an International Retrospective Study by the International Berlin-Frankfurt-Münster Study Group.
Topics: Adolescent; Anthracyclines; Antineoplastic Agents; Child; Child, Preschool; Chromosome Aberrations; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Cytarabine; Disease-Free Survival; Etoposide; Female; Germany; Hematopoietic Stem Cell Transplantation; Humans; Incidence; Induction Chemotherapy; International Cooperation; Kaplan-Meier Estimate; Karyotype; Leukemia, Myeloid, Acute; Male; Molecular Targeted Therapy; Mutation; Predictive Value of Tests; Proto-Oncogene Proteins c-kit; ras Proteins; Retrospective Studies; Translocation, Genetic; Transplantation, Homologous; Treatment Outcome | 2015 |
Midostaurin, bortezomib and MEC in relapsed/refractory acute myeloid leukemia.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bortezomib; Chromosome Aberrations; Cytarabine; Drug Monitoring; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Maximum Tolerated Dose; Middle Aged; Mitoxantrone; Recurrence; Remission Induction; Retreatment; Staurosporine; Treatment Outcome; Young Adult | 2016 |
Association between the TP53 Arg72Pro polymorphism and clinical outcomes in acute myeloid leukemia.
Topics: Adult; Aged; Aged, 80 and over; Alleles; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cytarabine; Daunorubicin; Etoposide; Female; Gene Expression; Genetic Predisposition to Disease; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Polymorphism, Single Nucleotide; Prognosis; Retrospective Studies; Survival Analysis; Thioguanine; Tumor Suppressor Protein p53 | 2017 |
Dic(9;20)(p13;q11) in childhood acute lymphoblastic leukaemia is related to low cellular resistance to asparaginase, cytarabine and corticosteroids.
Topics: Adolescent; Adrenal Cortex Hormones; Asparaginase; Child; Child, Preschool; Chromosome Aberrations; Chromosomes, Human, Pair 20; Chromosomes, Human, Pair 9; Cytarabine; Drug Resistance, Neoplasm; Humans; Infant; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2009 |
Cytosine arabinoside-induced cytogenotoxicity in bone marrow and spermatogonial cells of mice and its potential transmission through the male germline.
Topics: Animals; Antimetabolites, Antineoplastic; Bone Marrow; Chromosome Aberrations; Cytarabine; Female; Germ Cells; Male; Mice; Spermatogonia | 2009 |
Additional chromosomal abnormalities and their prognostic significance in adult Philadelphia-positive acute lymphoblastic leukemia: with or without imatinib in chemotherapy.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Benzamides; Chromosome Aberrations; Cyclophosphamide; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Kaplan-Meier Estimate; Male; Mercaptopurine; Methotrexate; Middle Aged; Mitoxantrone; Piperazines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Pyrimidines; Salvage Therapy; Vincristine; Vindesine; Young Adult | 2009 |
Intensive induction chemotherapy with regimen containing intermediate dose cytarabine in the treatment of de novo acute myeloid leukemia.
Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Female; Harringtonines; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Remission Induction; Young Adult | 2009 |
A der(1)t(1;21)(p36.3;q22) in a patient with acute myelogenous leukemia M2.
Topics: Chromosome Aberrations; Cytarabine; Daunorubicin; Female; Humans; In Situ Hybridization, Fluorescence; Leukemia, Myeloid, Acute; Middle Aged; Translocation, Genetic | 2010 |
Systemic mastocytosis associated with acute myeloid leukaemia.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Marrow Cells; Chromosome Aberrations; Cytarabine; Cytogenetic Analysis; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Mast Cells; Mastocytosis, Systemic | 2010 |
Day 15 bone marrow driven double induction in young adult patients with acute myeloid leukemia: feasibility, toxicity, and therapeutic results.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Bone Marrow; Chromosome Aberrations; Cytarabine; Disease-Free Survival; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Remission Induction; Retrospective Studies; Survival Rate; Time Factors; Transplantation, Homologous; Vidarabine; Young Adult | 2010 |
A prediction model for complete remission upon reinduction for patients with acute myeloid leukemia after failure of anthracycline and cytarabine standard chemotherapy.
Topics: Adult; Anthracyclines; Antimetabolites, Antineoplastic; Area Under Curve; Chromosome Aberrations; Cytarabine; Disease-Free Survival; Female; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Models, Theoretical; Remission Induction; Retrospective Studies; Treatment Failure; Treatment Outcome | 2011 |
High dose cytarabine and mitoxantrone: an effective induction regimen for high-risk acute myeloid leukemia (AML).
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Combined Modality Therapy; Cytarabine; Diarrhea; Dose-Response Relationship, Drug; Female; fms-Like Tyrosine Kinase 3; Hematologic Diseases; Humans; Infections; Kaplan-Meier Estimate; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Neoplasm Proteins; Neoplasms, Second Primary; Prognosis; Recurrence; Remission Induction; Retrospective Studies; Risk; Stem Cell Transplantation; Transplantation, Homologous; Young Adult | 2012 |
Induction chemotherapy versus palliative treatment for acute myeloid leukemia in a consecutive cohort of elderly patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Blood Component Transfusion; Chromosome Aberrations; Cohort Studies; Comorbidity; Cytarabine; Daunorubicin; Etoposide; Female; Follow-Up Studies; Humans; Hydroxyurea; Immunophenotyping; Kaplan-Meier Estimate; Karyotyping; Leukemia, Myeloid; Male; Palliative Care; Remission Induction; Retrospective Studies; Serbia; Treatment Outcome | 2012 |
[Genetic prognostic factors in childhood acute myeloid leukemia].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Chromosome Aberrations; Chromosome Deletion; Chromosome Disorders; Chromosomes, Human, Pair 7; Cytarabine; DNA Mutational Analysis; Etoposide; Female; fms-Like Tyrosine Kinase 3; Genes, Wilms Tumor; Genetic Markers; Humans; Idarubicin; Infant; Kaplan-Meier Estimate; Karyotyping; Leukemia, Myeloid, Acute; Male; Myelodysplastic Syndromes; Nuclear Proteins; Nucleophosmin; Prognosis; Survival Rate; Translocation, Genetic | 2012 |
Response of the G2-prophase checkpoint to genotoxic drugs in lymphocytes from healthy individuals.
Topics: Adult; Antibiotics, Antineoplastic; Chromosome Aberrations; Cytarabine; DNA Damage; Doxorubicin; Female; G2 Phase Cell Cycle Checkpoints; Humans; Hydroxyurea; Lymphocytes; Male; Prophase; Young Adult | 2012 |
A case of treatment-related myelodysplastic syndrome and acute myelogenous leukemia following high-dose chemotherapy with autologous stem cell transplantation for non-Hodgkin's lymphoma.
Topics: Adult; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; B-Lymphocytes; Bone Marrow Cells; Carmustine; Chromosome Aberrations; Chromosomes, Human, Pair 11; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Etoposide; Female; Gene Rearrangement; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Myelodysplastic Syndromes; Neoplasms, Second Primary; Pelvis; Pregnancy; Pregnancy Complications, Neoplastic; Transplantation, Autologous | 2002 |
Cellular drug resistance in childhood acute myeloid leukemia is related to chromosomal abnormalities.
Topics: Acute Disease; Adolescent; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Chromosome Aberrations; Chromosome Inversion; Chromosomes, Human; Cladribine; Cytarabine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Infant; Leukemia, Myeloid; Male; Neoplastic Stem Cells; Recurrence; Remission Induction; Tetrazolium Salts; Thiazoles; Translocation, Genetic; Trisomy | 2002 |
Acute myelogenous leukaemia in older patients at St Bartholomew's Hospital: outcome with mitoxantrone and cytarabine.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Chromosome Aberrations; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Ploidies; Prognosis; Remission Induction; Survival Analysis; Treatment Outcome | 2002 |
Correlation of three methods of measuring cytogenetic response in chronic myelocytic leukemia.
Topics: Bone Marrow Cells; Chromosome Aberrations; Chromosomes, Human; Cytarabine; Cytogenetic Analysis; Humans; In Situ Hybridization, Fluorescence; Interferon alpha-2; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukocytes; Randomized Controlled Trials as Topic; Recombinant Proteins | 2002 |
Double minutes containing amplified bcr-abl fusion gene in a case of chronic myeloid leukemia treated by imatinib.
Topics: Aneuploidy; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Blast Crisis; Chromosome Aberrations; Chromosome Painting; Combined Modality Therapy; Cytarabine; Drug Resistance, Neoplasm; Enzyme Inhibitors; Fatal Outcome; Fusion Proteins, bcr-abl; Gene Amplification; Humans; Hydroxyurea; Imatinib Mesylate; Interferon-alpha; Karyotyping; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Neoplasm Proteins; Peripheral Blood Stem Cell Transplantation; Philadelphia Chromosome; Piperazines; Pyrimidines; Transplantation, Autologous | 2003 |
HLA-DR antigen-negative acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cytarabine; Disease-Free Survival; Female; Flow Cytometry; HLA-DR Antigens; Humans; Idarubicin; Immunophenotyping; Karyotyping; Leukemia, Myeloid; Male; Middle Aged; Neoplastic Stem Cells; Prospective Studies; Recurrence; Treatment Outcome | 2003 |
Chromosomal rearrangement in Down syndrome with acute myeloid leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Chromosome Aberrations; Chromosome Deletion; Cytarabine; Daunorubicin; Down Syndrome; Female; Humans; Leukemia, Monocytic, Acute; Thioguanine; Translocation, Genetic | 2003 |
Prognostic relevance of immunophenotyping in 379 patients with acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cytarabine; Cytogenetics; Daunorubicin; DNA Nucleotidylexotransferase; Female; Humans; Immunophenotyping; Leukemia, Myeloid; Male; Middle Aged; Prognosis; Remission Induction; Survival Rate | 2004 |
Low L-selectin (CD62L) expression in acute myeloid leukemia correlates with a bad cytogenetic risk.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells; Chromosome Aberrations; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; L-Selectin; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Neoplasm Proteins; Neoplastic Stem Cells; Remission Induction; Risk; Thioguanine; Treatment Outcome; Tretinoin | 2003 |
X-irradiated human lymphocytes with unstable aberrations and their preferential elimination by p53/survivin-dependent apoptosis.
Topics: Apoptosis; Cell Cycle; Cells, Cultured; Chromosome Aberrations; Chromosomes, Human; Cytarabine; Dose-Response Relationship, Radiation; Gene Expression Regulation; Humans; Inhibitor of Apoptosis Proteins; Leukocytes, Mononuclear; Microtubule-Associated Proteins; Neoplasm Proteins; Radiation Dosage; Survivin; Tumor Suppressor Protein p53; X-Rays | 2003 |
Prolonged fever of unknown origin and hemophagocytosis evolving into acute lymphoblastic leukemia.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Chromosome Aberrations; Cyclophosphamide; Cytarabine; Disease Progression; Doxorubicin; Fever of Unknown Origin; Histiocytosis, Non-Langerhans-Cell; Humans; Karyotyping; Male; Methotrexate; Middle Aged; Pancytopenia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Rituximab; Splenomegaly; Vincristine | 2004 |
Pretreatment prognostic factors and treatment outcome in elderly patients with de novo acute myeloid leukemia.
Topics: Acute Disease; Aged; Aged, 80 and over; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Chromosome Aberrations; Cytarabine; Female; Hemoglobins; Humans; Karyotyping; L-Lactate Dehydrogenase; Leukemia, Myeloid; Leukocyte Count; Male; Neoplasm Staging; Platelet Count; Prognosis; Remission Induction; Risk Factors; Survival Rate; Treatment Outcome | 2005 |
Molecular basis for G2 arrest induced by 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine and consequences of checkpoint abrogation.
Topics: Antineoplastic Agents; Apoptosis; CDC2 Protein Kinase; Cell Line, Tumor; Checkpoint Kinase 1; Chromosome Aberrations; Cytarabine; DNA Damage; Drug Interactions; G2 Phase; Hematologic Neoplasms; Humans; Leukemia, Myeloid, Acute; Mitosis; Protein Kinases; Signal Transduction; Staurosporine | 2005 |
Prognostic factors and outcome of core binding factor acute myeloid leukemia patients with t(8;21) differ from those of patients with inv(16): a Cancer and Leukemia Group B study.
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Aziridines; Benzoquinones; Chromosome Aberrations; Cyclophosphamide; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Prognosis; Proportional Hazards Models; Prospective Studies; Remission Induction; Statistics, Nonparametric; Survival Analysis | 2005 |
Human stem cell factor-antibody [anti-SCF] enhances chemotherapy cytotoxicity in human CD34+ resistant myeloid leukaemia cells.
Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal; Antigens, CD34; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; bcl-2-Associated X Protein; Biomarkers, Tumor; Blast Crisis; Cell Line, Tumor; Chromosome Aberrations; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; Drug Synergism; Female; Humans; Leukemia, Myeloid, Acute; Male; Pilot Projects; Receptors, Cytokine; Stem Cell Factor; Treatment Outcome | 2006 |
Genetics in the management of adult de novo AML.
Topics: Acute Disease; Adult; Aged; Antimetabolites, Antineoplastic; Chromosome Aberrations; Chromosome Banding; Cytarabine; Hematopoietic Stem Cell Transplantation; Humans; In Situ Hybridization, Fluorescence; Karyotyping; Leukemia, Myeloid; Middle Aged; Multicenter Studies as Topic; Prognosis; Prospective Studies; Translocation, Genetic; Transplantation, Autologous; Treatment Outcome | 2003 |
Isolated extramedullary relapse after autologous bone marrow transplantation for acute myeloid leukemia: case report and review of the literature.
Topics: Aged; Antimetabolites, Antineoplastic; Bone Marrow Transplantation; Central Nervous System; Chromosome Aberrations; Chromosomes, Human, Pair 8; Combined Modality Therapy; Cytarabine; Fatal Outcome; Female; Humans; Leukemia, Myeloid, Acute; Radiography; Recurrence; Registries; Transplantation, Autologous; Transplantation, Homologous | 2006 |
Trisomy 19 as the sole chromosomal abnormality in proliferative chronic myelomonocytic leukemia.
Topics: Aged; Azacitidine; Chromosome Aberrations; Chromosomes, Human, Pair 19; Cytarabine; Cytogenetic Analysis; Daunorubicin; Decitabine; Dose-Response Relationship, Drug; Fatal Outcome; Female; Humans; Hydroxyurea; Leukemia, Myelomonocytic, Chronic; Male; Middle Aged; Myelodysplastic Syndromes; Phenotype; Steroids; Treatment Outcome | 2006 |
Complex karyotypic abnormalities in a case of acute myeloid leukaemia--M4Eo.
Topics: Adult; Antimetabolites, Antineoplastic; China; Chromosome Aberrations; Cytarabine; Fatal Outcome; Humans; Injections, Spinal; Karyotyping; Leukemia, Myelomonocytic, Acute; Male; Methotrexate | 2005 |
An antecedent diagnosis of refractory anemia with excess blasts has no prognostic relevance in acute myeloid leukemia of older adult patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Anemia, Refractory, with Excess of Blasts; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Combined Modality Therapy; Cytarabine; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Prognosis; Remission Induction; Stem Cell Transplantation; Vidarabine | 2006 |
Anti-clastogenic effect of beta-glucan extracted from barley towards chemically induced DNA damage in rodent cells.
Topics: Animals; Anthracenes; Antimetabolites, Antineoplastic; Antimutagenic Agents; beta-Glucans; Cells, Cultured; CHO Cells; Chromosome Aberrations; Cricetinae; Cricetulus; Cytarabine; DNA Damage; Hordeum; Methyl Methanesulfonate; Mutagens | 2006 |
[Acute monoblastic leukemia with tetrasomy 8].
Topics: Adult; Aneuploidy; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosomes, Human, Pair 8; Combined Modality Therapy; Cytarabine; Daunorubicin; Fatal Outcome; Female; Humans; Karyotyping; Leukemia, Monocytic, Acute; Peripheral Blood Stem Cell Transplantation | 2006 |
Significance of persistent Auer rods and cytogenetic abnormality after first cycle of therapy for acute promyelocytic leukaemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Examination; Chromosome Aberrations; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Cytarabine; Daunorubicin; Humans; In Situ Hybridization, Fluorescence; Leukemia, Promyelocytic, Acute; Male; Oncogene Proteins, Fusion; Remission Induction; Translocation, Genetic; Tretinoin | 2007 |
Cytogenetic study of the induction mechanism of chromosome-type aberrations by 1-beta-D-arabinofuranosylcytosine.
Topics: Adult; Antimetabolites, Antineoplastic; Chromosome Aberrations; Cycloheximide; Cytarabine; Cytogenetics; DNA Breaks, Double-Stranded; DNA Repair; Humans; In Vitro Techniques; Lymphocytes; Models, Biological; Mutagens; Plasmids; Protein Synthesis Inhibitors; Sister Chromatid Exchange | 2007 |
Therapy-related myelodysplastic syndrome and acute myeloid leukemia following treatment of acute myeloid leukemia: possible role of cytarabine.
Topics: Adult; Aged; Antineoplastic Agents; Chromosome Aberrations; Chromosomes, Human, Pair 7; Cytarabine; Female; Humans; Immunophenotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes | 2008 |
Mutated and non-mutated TP53 as targets in the treatment of leukaemia.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Death; Chromosome Aberrations; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Synergism; Furans; Genes, p53; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Membrane Proteins; Mutation; Nerve Tissue Proteins; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Vidarabine | 2008 |
The expression of DeltaNTP73, TATP73 and TP53 genes in acute myeloid leukaemia is associated with recurrent cytogenetic abnormalities and in vitro susceptibility to cytarabine cytotoxicity.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Chromosome Aberrations; Cytarabine; DNA-Binding Proteins; Drug Resistance, Neoplasm; Gene Expression; Gene Rearrangement; Genes, p53; Humans; Leukemia, Myeloid, Acute; Nuclear Proteins; Polymerase Chain Reaction; Recurrence; Tumor Suppressor Proteins | 2008 |
Molecular mechanisms involved in the production of chromosomal aberrations. III. Restriction endonucleases.
Topics: Animals; Caffeine; Cell Cycle; Cell Line; Chromosome Aberrations; Cricetinae; Cricetulus; Cytarabine; DNA Restriction Enzymes; Female; Fibroblasts; Karyotyping; Kinetics; Metaphase; Mice; Ovary | 1984 |
Induction of chromosome damage by Neurospora endonuclease in repair-inhibited quiescent normal human fibroblasts.
Topics: Cell Line; Chromosome Aberrations; Cytarabine; DNA Repair; Endonucleases; Fibroblasts; HeLa Cells; Humans; Hydroxyurea; Karyotyping; Kinetics; Mechlorethamine; Single-Strand Specific DNA and RNA Endonucleases | 1984 |
DNA repair and chromosome aberrations: the effect of cytosine arabinoside on the frequency of chromosome aberrations induced by radiation and chemicals.
Topics: 4-Nitroquinoline-1-oxide; Chromosome Aberrations; Chromosomes; Cytarabine; DNA Repair; Humans; In Vitro Techniques; Lymphocytes; Methyl Methanesulfonate; Time Factors; X-Rays | 1980 |
Nonrandom chromosome abnormalities in angioimmunoblastic lymphadenopathy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chromosome Aberrations; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Therapy, Combination; Female; Herpes Zoster; Humans; Immunoblastic Lymphadenopathy; Karyotyping; Leucovorin; Lymph Nodes; Lymphoma; Male; Methotrexate; Middle Aged; Prednisone; Procarbazine; Vinblastine; Vincristine | 1982 |
Induction and repair of DNA and chromosome damage by neocarzinostatin in quiescent normal human fibroblasts.
Topics: Antibiotics, Antineoplastic; Cell Line; Chromosome Aberrations; Chromosomes, Human; Cycloheximide; Cytarabine; DNA Repair; DNA Replication; Fibroblasts; Humans; Karyotyping; Kinetics; Zinostatin | 1982 |
[The repair of DNA damage induced in human lymphocytes by gamma rays and fast neurons].
Topics: Adult; Chromosome Aberrations; Cytarabine; DNA Repair; Fast Neutrons; Gamma Rays; Humans; Lymphocytes; Male | 1984 |
Prognostic factors in adult patients with acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Chromosome Aberrations; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Prednisolone; Prognosis; Vincristine; Zinostatin | 1983 |
High frequencies of chromatid aberrations produced during G2 in human lymphocytes by very low doses (0.025-0.4 Gy) of X-rays in combination with inhibitors of DNA synthesis.
Topics: Chromatids; Chromosome Aberrations; Cytarabine; Deoxyadenosines; DNA Replication; Dose-Response Relationship, Radiation; Humans; Hydroxyurea; Interphase; Lymphocytes | 1984 |
Kinetics of micronucleus formation in relation to chromosomal aberrations in mouse bone marrow.
Topics: Animals; Bone Marrow; Cell Nucleus; Chromosome Aberrations; Cytarabine; Erythrocytes, Abnormal; Male; Mercaptopurine; Mice; Mitomycin; Mitomycins; Mitosis; Mutagenicity Tests; Time Factors | 1984 |
The mechanism of 3-aminobenzamide-mediated increases in spontaneous and induced SCEs.
Topics: Alkylating Agents; Animals; Antipain; Benzamides; Bromodeoxyuridine; Cell Line; Chromosome Aberrations; Cricetinae; Cricetulus; Cytarabine; Female; Fibroblasts; Ovary; Poly(ADP-ribose) Polymerase Inhibitors; Sister Chromatid Exchange | 1984 |
X-ray-induced chromosome aberrations in Down lymphocytes: an explanation of their increased sensitivity.
Topics: Chromosome Aberrations; Cytarabine; Down Syndrome; Humans; Lymphocytes; Radiation, Ionizing; X-Rays | 1981 |
Liquid-holding experiments with human peripheral lymphocytes. II. Experiments with trenimon and 1-beta-D-arabinosylcytosine.
Topics: Cells, Cultured; Chromosome Aberrations; Crossing Over, Genetic; Cytarabine; DNA Repair; Humans; Lymphocytes; Sister Chromatid Exchange; Triaziquone | 1984 |
Possible correlations between cell killing, chromosome damage and DNA repair after X-irradiation.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Survival; Chromosome Aberrations; Cytarabine; DNA Repair; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Mice; X-Rays | 1984 |
Quantitative analysis of chromosomal G-bands in human hematopoietic disorders by methotrexate synchronization technique.
Topics: Anemia; Bone Marrow; Cell Cycle; Chromosome Aberrations; Chromosome Banding; Chromosome Disorders; Cytarabine; Hematologic Diseases; Humans; Karyotyping; Kinetics; Leukemia; Metaphase; Methotrexate | 1984 |
[Low-dose cytosine arabinoside (Ara-C) continuous infusion regimen for atypical nonlymphocytic leukemia--clinical study of the remission mechanism by serial chromosomal findings, colony formation and plasma Ara-C concentration].
Topics: Aged; Chromosome Aberrations; Cytarabine; Drug Administration Schedule; Female; Hematopoietic Stem Cells; Humans; Leukemia; Male; Middle Aged | 1984 |
Chromosomes and causation of human cancer and leukemia. LIII. Comprehensive cytogenetic analysis of an erythroleukemia.
Topics: Aged; Bone Marrow; Chromosome Aberrations; Chromosome Banding; Chromosome Disorders; Cytarabine; Humans; Karyotyping; Leukemia, Erythroblastic, Acute; Male; Metaphase; Polyploidy; Sister Chromatid Exchange | 1983 |
The relationship between growth in agar, karyotype and prognosis in acute leukaemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells; Cells, Cultured; Chromosome Aberrations; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Karyotyping; Leukemia; Leukemia, Lymphoid; Male; Middle Aged; Neoplastic Stem Cells; Prednisolone; Prednisone; Prognosis; Thioguanine; Vincristine | 1984 |
[Double minute chromosomes (DMs) in a case of acute myelocytic leukemia (M2: FAB classification)].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Prednisolone; Vincristine | 1984 |
TdT-positive acute leukemia with monocytoid characteristics: clinical, cytochemical, cytogenetic, and immunologic findings.
Topics: Acute Disease; Adult; Aged; Antibodies, Monoclonal; Cell Membrane; Chromosome Aberrations; Cytarabine; Daunorubicin; DNA Nucleotidylexotransferase; DNA Nucleotidyltransferases; Female; Histocytochemistry; Humans; Leukemia; Male; Middle Aged; Monocytes; Neoplastic Stem Cells; Phenotype; Prednisone; Vincristine | 1984 |
The induction of chromosome-type aberrations in G1 by methyl methanesulfonate and 4-nitroquinoline-N,-oxide, and the non-requirement of an S-phase for their production.
Topics: 4-Nitroquinoline-1-oxide; Cells, Cultured; Chromosome Aberrations; Chromosomes; Cytarabine; Drug Therapy, Combination; Humans; Interphase; Lymphocytes; Methyl Methanesulfonate; Mutagens | 1981 |
Repair of chromosome damage induced by X-irradiation during G2 phase in a line of normal human fibroblasts and its malignant derivative.
Topics: 4-Nitroquinoline-1-oxide; Caffeine; Catalase; Cell Line; Cell Transformation, Neoplastic; Chromosome Aberrations; Cytarabine; DNA Repair; Fibroblasts; Humans; Interphase; Mannitol; Radiation Dosage | 1982 |
The use of inhibitors of DNA-repair in the study of the mechanisms of induction of chromosome aberrations.
Topics: Aphidicolin; Cell Cycle; Chromosome Aberrations; Cytarabine; Diterpenes; DNA Repair; Humans; In Vitro Techniques; Lymphocytes | 1982 |
Therapy of secondary acute nonlymphocytic leukemia with cytarabine.
Topics: Acute Disease; Adult; Aged; Chromosome Aberrations; Cytarabine; Humans; Leukemia; Middle Aged | 1983 |
Restoration of nonclonal hematopoiesis in chronic myelogenous leukemia (CML) following a chemotherapy-induced loss of the Ph1 chromosome.
Topics: Adult; Chromosome Aberrations; Chromosomes, Human, 21-22 and Y; Clone Cells; Cytarabine; Daunorubicin; Female; Glucosephosphate Dehydrogenase; Heterozygote; Humans; Karyotyping; Leukemia, Myeloid; Thioguanine | 1980 |
Double minute chromosomes in a case of acute myelogenous leukemia resistant to chemotherapy.
Topics: Aged; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Daunorubicin; Female; Humans; Karyotyping; Leukemia, Myeloid, Acute | 1981 |
Acute megakaryoblastic leukaemia associated with intrinsic platelet dysfunction and constitution ring 21 chromosome in a young boy.
Topics: Bone Marrow; Child, Preschool; Chromosome Aberrations; Chromosomes, Human, 21-22 and Y; Cytarabine; Doxorubicin; Drug Therapy, Combination; Fluorescent Antibody Technique; Humans; Karyotyping; Male; Platelet Function Tests; Thrombocythemia, Essential | 1982 |
Normal response of fanconi's anemia cells to high concentrations of O2 as determined by alkaline elution.
Topics: Anemia, Aplastic; Chromosome Aberrations; Chromosomes; Cytarabine; DNA; Erythrocytes; Fanconi Anemia; Humans; Oxygen | 1982 |
Cytosar-induced micronuclei and chromosomal aberrations in mouse bone-marrow cells.
Topics: Animals; Bone Marrow; Cell Nucleus; Chromosome Aberrations; Chromosomes; Cytarabine; Male; Mice; Mutagenicity Tests | 1981 |
Evidence for double replication of chromosomal DNA segments as a general consequence of DNA replication inhibition.
Topics: Cell Line; Chromosome Aberrations; Cycloheximide; Cytarabine; DNA Repair; DNA Replication; DNA-Directed DNA Polymerase; Humans; Interphase; Vidarabine | 1981 |
Effects of 1-beta-D-arabinofuranosylcytosine on chromosomes, depending upon the cell cycle stage at the time of exposure.
Topics: Animals; Cell Cycle; Cell Line; Chromatids; Chromosome Aberrations; Chromosomes; Cytarabine; Dose-Response Relationship, Drug; Macropodidae; X-Rays | 1981 |
The effect of cytosine arabinoside on the frequency of X-ray-induced chromosome aberrations in normal human leukocytes.
Topics: Cells, Cultured; Chromosome Aberrations; Chromosomes, Human; Cytarabine; DNA; DNA Repair; Humans; Lymphocytes; Time Factors; X-Rays | 1980 |
Antagonizing effect of triphenyltin chloride on cytosine-1-beta-D-arabinofuranoside potentiation of chromosome aberrations induced by mitomycin C.
Topics: Animals; Caffeine; CHO Cells; Chromosome Aberrations; Cricetinae; Cytarabine; Drug Antagonism; Drug Synergism; G2 Phase; Hydroxyurea; Mitomycin; Mutagenesis; Organotin Compounds | 1994 |
CD34 expression is associated with major adverse prognostic factors in adult acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Aged; Amsacrine; Aneuploidy; Antibiotics, Antineoplastic; Antigens, CD; Antigens, CD34; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Biomarkers, Tumor; Bone Marrow Transplantation; Burkitt Lymphoma; Cell Differentiation; Chromosome Aberrations; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Disease-Free Survival; Female; Humans; Immunophenotyping; Life Tables; Logistic Models; Male; Middle Aged; Neoplastic Stem Cells; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Proportional Hazards Models; Remission Induction; Risk Factors; Salvage Therapy; Survival Analysis; Vincristine | 1995 |
In vitro-induced resistance to the deoxycytidine analogues cytarabine (AraC) and 5-aza-2'-deoxycytidine (DAC) in a rat model for acute myeloid leukemia is mediated by mutations in the deoxycytidine kinase (dck) gene.
Topics: Animals; Antineoplastic Agents; Azacitidine; Base Sequence; Chromosome Aberrations; Cytarabine; Decitabine; Deoxycytidine Kinase; Drug Resistance; In Situ Hybridization, Fluorescence; Leukemia, Myeloid, Acute; Molecular Sequence Data; Point Mutation; Polymorphism, Single-Stranded Conformational; Rats; Translocation, Genetic; Tumor Cells, Cultured | 1995 |
Heterogeneity in chemical mutagen-induced chromosome damage after G2 phase exposure to bleomycin, ara-C and gentian violet in cultured lymphocytes of beta-thalassaemia traits.
Topics: Adult; beta-Thalassemia; Bleomycin; Cells, Cultured; Chromosome Aberrations; Cytarabine; Female; G2 Phase; Gentian Violet; Humans; Male; Middle Aged | 1995 |
G2 phase repair of X-ray-induced chromosomal DNA damage in trichothiodystrophy cells.
Topics: Abnormalities, Multiple; Ataxia Telangiectasia; Cell Line; Chromosome Aberrations; Chromosomes, Human; Cockayne Syndrome; Cytarabine; DNA Damage; DNA Repair; Down Syndrome; G2 Phase; Hair; Humans; Skin; Skin Diseases; X-Rays; Xeroderma Pigmentosum | 1995 |
Evidence that the product of the xrs gene is predominantly involved in the repair of a subset of radiation-induced interphase chromosome breaks rejoining with fast kinetics.
Topics: Animals; CHO Cells; Chromosome Aberrations; Chromosomes; Cricetinae; Cytarabine; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Interphase; Kinetics; Time Factors; X-Rays | 1994 |
Evidence for excision repair-dependent and -independent processes in ara C-induced chromosome rearrangements in G1 human lymphocytes.
Topics: Adolescent; Adult; Child; Chromosome Aberrations; Cytarabine; DNA Repair; G1 Phase; Gene Rearrangement; Humans; Lymphocytes; Nucleic Acid Synthesis Inhibitors; Sister Chromatid Exchange; Xeroderma Pigmentosum | 1993 |
High frequency of etoposide (VP-16)-related secondary leukemia in children with non-Hodgkin's lymphoma.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparagine; Child; Child, Preschool; Chromosome Aberrations; Chromosomes, Human, Pair 11; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Life Tables; Lymphoma, Non-Hodgkin; Male; Mercaptopurine; Methotrexate; Neoplasms, Second Primary; Risk; Vincristine | 1993 |
[Successful treatment with combination chemotherapy of BHAC-AMP in a case of acute myelofibrosis developed from myelodysplastic syndrome with multiple chromosomal aberrations].
Topics: Aclarubicin; Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Chromosome Aberrations; Cytarabine; Humans; Male; Mercaptopurine; Middle Aged; Myelodysplastic Syndromes; Prednisolone; Primary Myelofibrosis | 1993 |
Incidence of chromosome abnormalities and clinical significance of karyotype in de novo acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Daunorubicin; Female; Humans; Incidence; Karyotyping; Leukemia, Myeloid; Male; Middle Aged; Prognosis; Translocation, Genetic | 1993 |
Is there still a role for low-dose cytosine arabinoside in de novo acute myeloid leukemia in the elderly? A report on 77 cases.
Topics: Aged; Aged, 80 and over; Chromosome Aberrations; Chromosomes, Human, Pair 5; Chromosomes, Human, Pair 7; Cytarabine; Female; Humans; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Remission Induction; Survival Rate | 1993 |
Radiosensitivity and effects of repair inhibitors for X-ray-induced chromosomal damage in mouse zygotes in S and G2 phases.
Topics: Animals; Benzamides; Caffeine; Chromosome Aberrations; Cytarabine; DNA Repair; Female; G2 Phase; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Radiation Tolerance; S Phase; X-Rays; Zygote | 1995 |
Modulation of radiation-induced chromosomal damage by inhibitors of DNA repair and flow cytometric analysis in ataxia telangiectasia cells with 'intermediate radiosensitivity'.
Topics: Aphidicolin; Ataxia Telangiectasia; Cell Cycle; Cells, Cultured; Chromosome Aberrations; Chromosomes, Human; Cytarabine; Dimethyl Sulfoxide; DNA Damage; DNA Repair; Flow Cytometry; G1 Phase; G2 Phase; Humans; Hydroxyurea; Lymphocytes; Nucleic Acid Synthesis Inhibitors; Radiation Tolerance; S Phase; Time Factors; X-Rays | 1995 |
FLANG (fludarabine + cytosine arabinoside + novantrone + G-CSF) induces partial remission in lymphoid blast transformation of Ph+chronic myelogenous leukaemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Bone Marrow; Bone Marrow Transplantation; Chromosome Aberrations; Combined Modality Therapy; Cytarabine; Disease Progression; Granulocyte Colony-Stimulating Factor; Humans; Hydroxyurea; Immunologic Factors; Interferon-alpha; Karyotyping; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Mercaptopurine; Middle Aged; Mitoxantrone; Remission Induction; Vidarabine | 1996 |
Establishment and characterization of a novel acute promyelocytic leukemia cell line (UF-1) with retinoic acid-resistant features.
Topics: Adult; Antineoplastic Agents; Cell Differentiation; Cell Division; Chromosome Aberrations; Cytarabine; Daunorubicin; DNA Mutational Analysis; Drug Resistance, Neoplasm; Fatal Outcome; Female; HL-60 Cells; Humans; Immunophenotyping; Karyotyping; Leukemia, Promyelocytic, Acute; Mercaptopurine; Neoplasm Proteins; Oncogene Proteins, Fusion; Polymerase Chain Reaction; Prednisolone; Tretinoin; Tumor Cells, Cultured | 1996 |
[CD7, HLA-DR, CD38 positive acute undifferentiated leukemia with subcutaneous tumor and thymoma].
Topics: Acute Disease; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Antigens, CD; Antigens, CD7; Antigens, Differentiation; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Etoposide; Gene Rearrangement; HLA-DR Antigens; Humans; Immunoglobulin Heavy Chains; Immunophenotyping; Leukemia; Membrane Glycoproteins; Mitoxantrone; N-Glycosyl Hydrolases; Prednisolone; Receptors, Antigen, T-Cell, gamma-delta; Remission Induction; Skin Neoplasms; Thymoma; Thymus Neoplasms | 1996 |
Differentiation induction therapy with all-trans retinoic acid (ATRA) in a patient with secondary 11q23 leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, Pair 11; Cytarabine; Drug Resistance, Multiple; Etoposide; Humans; Leukemia, Promyelocytic, Acute; Male; Translocation, Genetic; Tretinoin | 1996 |
Secondary cytogenetic changes in acute promyelocytic leukemia--prognostic importance in patients treated with chemotherapy alone and association with the intron 3 breakpoint of the PML gene: a Cancer and Leukemia Group B study.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Chromosomes, Human, Pair 8; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Prognosis; Prospective Studies; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Translocation, Genetic | 1997 |
Detection of MNNG-induced DNA lesions in mammalian cells; validation of comet assay against DNA unwinding technique, alkaline elution of DNA and chromosomal aberrations.
Topics: Animals; Cell Line; Child; Chromatids; Chromosome Aberrations; Cricetinae; Cytarabine; DNA; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Humans; Hydroxyurea; Male; Metaphase; Methylnitronitrosoguanidine; Mutagenesis; Mutagenicity Tests; Mutagens; Reproducibility of Results; Skin; Tumor Cells, Cultured | 1997 |
Early transformation to acute myeloblastic leukaemia with the acquisition of inv(16) in Ph positive chronic granulocytic leukaemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosome Disorders; Chromosome Inversion; Chromosome Mapping; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 22; Chromosomes, Human, Pair 9; Cytarabine; Fatal Outcome; Humans; Idarubicin; Karyotyping; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Philadelphia Chromosome | 1997 |
Induction of a hematological and cytogenetic remission in a patient with a myelodysplastic syndrome secondary to Fanconi's anemia employing the S-HAM regimen.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cytarabine; Fanconi Anemia; Female; Humans; Karyotyping; Mitoxantrone; Myelodysplastic Syndromes; Remission Induction | 1997 |
High remission rate, short remission duration in patients with refractory anemia with excess blasts (RAEB) in transformation (RAEB-t) given acute myelogenous leukemia (AML)-type chemotherapy in combination with granulocyte-CSF (G-CSF).
Topics: Adult; Anemia, Refractory, with Excess of Blasts; Bone Marrow; Chromosome Aberrations; Chromosome Disorders; Confidence Intervals; Cytarabine; Disease-Free Survival; Drug Administration Schedule; Drug Therapy, Combination; Environment, Controlled; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Karyotyping; Leukemia, Myeloid, Acute; Middle Aged; Platelet Count; Probability; Prognosis; Recurrence; Remission Induction; Retrospective Studies; Survival Rate; Vidarabine | 1995 |
The prognostic significance of chromosomal analysis and immunophenotyping in 117 patients with de novo acute myeloid leukemia.
Topics: Acute Disease; Adult; Aged; Antibiotics, Antineoplastic; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antimetabolites, Antineoplastic; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Immunophenotyping; Karyotyping; Leukemia, Myeloid; Male; Middle Aged; Multivariate Analysis; Prognosis; Remission Induction; Retrospective Studies; Sialic Acid Binding Ig-like Lectin 3 | 1997 |
Inv(16) acute myeloid leukemia cells show an increased sensitivity to cytosine arabinoside in vitro.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Apoptosis; Chromosome Aberrations; Chromosome Inversion; Chromosomes, Human, Pair 16; Cytarabine; DNA, Neoplasm; Drug Screening Assays, Antitumor; Female; Humans; Karyotyping; Leukemia, Myeloid; Male; Middle Aged; Tumor Cells, Cultured | 1998 |
Fewer chromosome aberrations and earlier apoptosis induced by DNA synthesis inhibitors, a topoisomerase II inhibitor or alkylating agents in human cells with normal compared with mutant p53.
Topics: Alkylating Agents; Antineoplastic Agents; Aphidicolin; Apoptosis; B-Lymphocytes; Cell Division; Cell Line; Chromosome Aberrations; Cytarabine; DNA Replication; Etoposide; Humans; Hydroxyurea; Methotrexate; Mutagenesis; Nucleic Acid Synthesis Inhibitors; Radiation, Ionizing; Topoisomerase II Inhibitors; Tumor Suppressor Protein p53 | 1998 |
Clonal myelodysplastic cells present in apheresis product before transplantation.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carmustine; Chromosome Aberrations; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 7; Cyclophosphamide; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cells; Humans; In Situ Hybridization, Fluorescence; Karyotyping; Lymphoma, B-Cell; Lymphoma, Follicular; Melphalan; Middle Aged; Podophyllotoxin; Retrospective Studies | 1998 |
Long-term disappearance of previous chromosomal abnormalities in myelodysplastic syndromes treated with low dose cytosine arabinoside and granulocyte/macrophage-colony stimulating factor.
Topics: Aged; Anemia, Refractory; Anemia, Sideroblastic; Chromosome Aberrations; Cytarabine; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunologic Factors | 1998 |
The contribution of deficient DNA repair to chromosomal radiosensitivity of CHO cells after G2 irradiation.
Topics: Animals; Cell Division; Cell Line; CHO Cells; Chromosome Aberrations; Chromosomes; Cricetinae; Cytarabine; DNA Helicases; DNA Repair; DNA Repair Enzymes; DNA-Binding Proteins; Drosophila Proteins; Humans; Lymphocytes; Poly-ADP-Ribose Binding Proteins; Radiation Tolerance; Recombinant Proteins; Transfection; Ultraviolet Rays; X-Rays | 1999 |
Analysis of bleomycin- and cytosine arabinoside-induced chromosome aberrations involving chromosomes 1 and 4 by painting FISH.
Topics: Adult; Bleomycin; Chromatin; Chromosome Aberrations; Chromosome Breakage; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 4; Cytarabine; DNA Damage; DNA Repair; DNA Replication; Humans; In Situ Hybridization, Fluorescence; Lymphocytes; Male; Mitotic Index; Mutagens; Mutation | 1999 |
Acute promyelocytic leukaemia: a retrospective analysis of patients treated at St. Bartholomew's Hospital 1969-1995.
Topics: Adult; Antibiotics, Antineoplastic; Antineoplastic Agents; Chromosome Aberrations; Cytarabine; Female; Humans; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Recurrence; Remission Induction; Retinoids; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Survival Rate; Time Factors; United Kingdom | 1999 |
Cell cycle specificity of cytogenetic damage induced by 3,4-epoxy-1- butene.
Topics: Cell Cycle; Chromosome Aberrations; Cytarabine; DNA; DNA Repair; Epoxy Compounds; Humans; In Vitro Techniques; Lymphocytes; Mutagens; Resting Phase, Cell Cycle; Sister Chromatid Exchange | 1999 |
A comparison of the roles of p53 mutation and AraC inhibition in the enhancement of bleomycin-induced chromatid aberrations in mouse and human cells.
Topics: Animals; Bleomycin; Cell Line; Cells, Cultured; Chromosome Aberrations; Cytarabine; DNA Repair; Dose-Response Relationship, Drug; G2 Phase; Humans; Mice; Mice, Knockout; Mitomycin; Mitotic Index; Mutation; Nucleic Acid Synthesis Inhibitors; S Phase; Tumor Suppressor Protein p53 | 2000 |
High-dose cytosine arabinoside and daunorubicin induction therapy for adult patients with de novo non M3 acute myelogenous leukemia: impact of cytogenetics on achieving a complete remission.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Diseases; Chromosome Aberrations; Chromosome Deletion; Chromosome Inversion; Chromosomes, Human; Chromosomes, Human, Pair 7; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Logistic Models; Male; Middle Aged; Prognosis; Remission Induction; Retrospective Studies; Sepsis; Translocation, Genetic; Treatment Outcome | 2000 |
Prognostic factors in children and adolescents with acute myeloid leukemia (excluding children with Down syndrome and acute promyelocytic leukemia): univariate and recursive partitioning analysis of patients treated on Pediatric Oncology Group (POG) Study
Topics: Adolescent; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bone Marrow Transplantation; Child; Chromosome Aberrations; Chromosome Inversion; Chromosomes, Human; Cohort Studies; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Leukemia, Myeloid; Life Tables; Male; Multicenter Studies as Topic; Prognosis; Proportional Hazards Models; Randomized Controlled Trials as Topic; Remission Induction; Risk Assessment; Risk Factors; Survival Analysis; Thioguanine; Translocation, Genetic; Treatment Failure; Treatment Outcome; United States | 2000 |
Double minute chromosomes and c-MYC amplification in a child with secondary myelodysplastic syndrome after treatment for acute lymphoblastic leukemia.
Topics: Anemia, Refractory, with Excess of Blasts; Aneuploidy; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Chromosome Aberrations; Chromosomes, Human, Pair 8; Cladribine; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Daunorubicin; Fatal Outcome; Female; Gene Amplification; Genes, myc; Humans; Hydrocortisone; Karyotyping; Mercaptopurine; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Vincristine | 2000 |
Acute megakaryocytic leukemia: the Eastern Cooperative Oncology Group experience.
Topics: Adolescent; Adult; Aged; Anthracyclines; Antigens; Antigens, CD7; Antineoplastic Combined Chemotherapy Protocols; Blood Platelets; Bone Marrow; CD2 Antigens; Chromosome Aberrations; Chromosomes, Human, Pair 3; Cytarabine; Female; Humans; Immunophenotyping; Leukemia, Megakaryoblastic, Acute; Male; Middle Aged; Peroxidase; Randomized Controlled Trials as Topic; Remission Induction; Retrospective Studies; Survival Rate | 2000 |
Explaining the high mutation rates of cancer cells to drug and multidrug resistance by chromosome reassortments that are catalyzed by aneuploidy.
Topics: Aneuploidy; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Cell Size; CHO Cells; Chromosome Aberrations; Cricetinae; Cytarabine; Demecolcine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Male; Methotrexate; Mice; Mutation; Puromycin; Tumor Cells, Cultured | 2000 |
Acute promyelocytic leukemia with additional chromosome abnormalities in a renal transplant case.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 13; Chromosomes, Human, Pair 14; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Chromosomes, Human, Pair 22; Cytarabine; Humans; Idarubicin; Immunosuppressive Agents; In Situ Hybridization, Fluorescence; Kidney Transplantation; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Mitoxantrone; Polycystic Kidney Diseases; Recurrence; Remission Induction; Reverse Transcriptase Polymerase Chain Reaction; Tretinoin | 2001 |
Amplification of ERBB2, RARA, and TOP2A genes in a myelodysplastic syndrome transforming to acute myeloid leukemia.
Topics: Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Cell Transformation, Neoplastic; Chromosome Aberrations; Chromosome Mapping; Chromosomes, Human, Pair 17; Chromosomes, Human, Pair 9; Cytarabine; Daunorubicin; DNA Topoisomerases, Type II; DNA-Binding Proteins; Female; Genes, erbB-2; Humans; In Situ Hybridization, Fluorescence; Isoenzymes; Karyotyping; Leukemia, Myelomonocytic, Acute; Metaphase; Middle Aged; Myelodysplastic Syndromes; Poly-ADP-Ribose Binding Proteins; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Thioguanine | 2001 |
Myelodysplastic syndrome progresses rapidly into erythroleukemia associated with synchronous double cancers of the stomach and the papilla of Vater.
Topics: Aclarubicin; Adenocarcinoma; Aged; Ampulla of Vater; Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cholestasis, Extrahepatic; Chromosome Aberrations; Chromosome Disorders; Common Bile Duct Neoplasms; Cytarabine; Disease Progression; Granulocyte Colony-Stimulating Factor; Humans; Karyotyping; Leukemia, Erythroblastic, Acute; Male; Neoplasms, Multiple Primary; Neoplasms, Second Primary; Pancytopenia; Stomach Neoplasms | 2001 |
Repetitious appearance and disappearance of different kinds of clonal cytogenetic abnormalities after allogeneic bone marrow transplantation.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Child, Preschool; Chromosome Aberrations; Chromosome Disorders; Clone Cells; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; DNA Damage; Female; Follow-Up Studies; Humans; In Situ Hybridization, Fluorescence; Karyotyping; Mercaptopurine; Methotrexate; Methylprednisolone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Remission Induction; Time Factors; Transplantation Conditioning; Transplantation, Homologous; Vincristine | 2001 |
Acute basophilic leukemia.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Chromosome Aberrations; Coloring Agents; Cytarabine; Cytoplasmic Granules; Fatal Outcome; Humans; Idarubicin; Immunophenotyping; Karyotyping; Leukemia, Basophilic, Acute; Leukocyte Count; Male; Middle Aged; Neoplasm Proteins; Neoplastic Stem Cells; Periodic Acid-Schiff Reaction; Peroxidase; Recurrence; Tolonium Chloride; Translocation, Genetic | 2001 |
X-ray-induced chromosome aberrations in human lymphocytes in vitro are potentiated under simulated microgravity conditions (Clinostat).
Topics: Antimetabolites, Antineoplastic; Cell Division; Cells, Cultured; Chromosome Aberrations; Cytarabine; DNA Repair; Humans; Lymphocytes; Resting Phase, Cell Cycle; Rotation; Weightlessness Simulation; X-Rays | 2001 |
Cytogenetic effects of hexavalent chromium in Bulgarian chromium platers.
Topics: Adult; Antimetabolites, Antineoplastic; Bulgaria; Carcinogens, Environmental; Cells, Cultured; Chromium; Chromosome Aberrations; Cohort Studies; Cytarabine; Cytogenetic Analysis; Female; Humans; Inhalation Exposure; Lymphocytes; Male; Micronuclei, Chromosome-Defective; Micronucleus Tests; Middle Aged; Mouth Mucosa; Mutagenicity Tests; Occupational Exposure; Sister Chromatid Exchange | 2002 |
CD56 expression in myeloperoxidase-negative FAB M5 acute myeloid leukemia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bone Marrow Transplantation; CD56 Antigen; Chromosome Aberrations; Chromosomes, Human, Pair 11; Cytarabine; Fatal Outcome; Female; Humans; Immunophenotyping; In Situ Hybridization, Fluorescence; Leukemia, Myeloid, Acute; Male; Middle Aged; Peroxidase; Recurrence; Remission Induction | 2002 |
Clonal evolution of blasts in an elderly patient with CD56(+) relapsed acute promyelocytic leukemia.
Topics: Aged; Antineoplastic Agents; CD56 Antigen; Chromosome Aberrations; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Chromosomes, Human, Pair 8; Cytarabine; Female; Flow Cytometry; Granulocyte Colony-Stimulating Factor; Humans; Karyotyping; Leukemia, Promyelocytic, Acute; Prognosis; Recombinant Proteins; Recurrence; Remission Induction; Reverse Transcriptase Polymerase Chain Reaction; Translocation, Genetic | 2002 |
FAB M4 and high CD14 surface expression is associated with high cellular resistance to Ara-C and daunorubicin: implications for clinical outcome in acute myeloid leukaemia.
Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Amsacrine; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cohort Studies; Cytarabine; Daunorubicin; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Idarubicin; Leukemia, Myeloid; Leukemia, Myelomonocytic, Acute; Lipopolysaccharide Receptors; Male; Middle Aged; Mitoxantrone; Multivariate Analysis; Neoplastic Stem Cells; Thioguanine; Treatment Outcome | 2001 |
Heterogeneity of morphological, cytochemical, and cytogenetic features in the blastic phase of chronic granulocytic leukemia.
Topics: Acute Disease; Adult; Alkaline Phosphatase; Aneuploidy; Biopsy; Bone Marrow; Bone Marrow Cells; Cell Nucleus; Child; Chromosome Aberrations; Cytarabine; Cytoplasm; Female; Histocytochemistry; Humans; Leukemia, Myeloid; Male; Microscopy, Electron; Middle Aged; Mitochondria; Organoids; Peroxidases; Prednisone; Remission, Spontaneous; Staining and Labeling; Thioguanine; Vincristine | 1975 |
Ten model mutagens evaluated by the micronucleus test.
Topics: Animals; Bleomycin; Bone Marrow; Bone Marrow Cells; Cell Line; Cell Nucleus; Chromosome Aberrations; Cyclophosphamide; Cytarabine; Demecolcine; Dose-Response Relationship, Drug; Doxorubicin; Erythroblasts; Fluorouracil; Genetic Techniques; Mercaptopurine; Methotrexate; Mice; Mutagens; Thiotepa; Vincristine | 1976 |
Sister-chromatid exchanges in human lymphocytes exposed during Go to four classes of DNA-damaging chemicals.
Topics: Bleomycin; Cell Cycle; Chlorambucil; Chromatids; Chromosome Aberrations; Cytarabine; DNA; Humans; Lymphocytes; Methotrexate; Mitomycins; Mutagens; Thiotepa | 1979 |
A case of acute myeloblastic leukemia with Ph1 chromosome showing translocation 9q+;22q-.
Topics: Chromosome Aberrations; Chromosomes, Human, 21-22 and Y; Chromosomes, Human, 6-12 and X; Cytarabine; Humans; Japan; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Nuclear Warfare; Prednisolone; Translocation, Genetic | 1977 |
[Incidence of the Philadelphia chromosome before and after DCMP-therapy during the chronic phase of chronic myelocytic leukemia (author's transl)].
Topics: Adult; Chromosome Aberrations; Chromosomes, Human, 21-22 and Y; Cytarabine; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid; Male; Mercaptopurine; Mitobronitol; Prednisone | 1977 |
[Trysomy of chromosome 1 long arms plus chromosome 9 inversion in leukaemic cells (author's transl)].
Topics: Chromosome Aberrations; Chromosome Disorders; Cytarabine; Daunorubicin; Drug Resistance; Female; Humans; Karyotyping; Leukemia, Myeloid, Acute; Middle Aged; Trisomy | 1978 |
Evidence for a new mechanism of cytotoxicity of 1-beta-D arabinofuranosylcytosine.
Topics: Cell Cycle; Cell Line; Cell Survival; Chromosome Aberrations; Cytarabine; DNA; DNA Replication; Humans; Lymphocytes; Models, Biological; Neoplasms, Experimental | 1979 |
Nonrandom distribution of chromosomal aberrations induced by three chemicals.
Topics: Cells, Cultured; Chromosome Aberrations; Chromosome Banding; Chromosomes; Cisplatin; Cytarabine; Genetic Variation; Humans; Lymphocytes; Triethylenemelamine | 1979 |
[Chemotherapy and mutagenesis. A study of chromosome aberrations as a test for mutagenesis after the use of cyclophosphamide, methotrexate and cytosine arabinoside].
Topics: Child; Chromosome Aberrations; Cyclophosphamide; Cytarabine; Humans; Lymphocytes; Methotrexate; Mutagenicity Tests | 1979 |
The effect of the mode of administration of nitrogen mustard and cytosine arabinoside on the production of chromosomal aberrations in mouse bone marrow and ascites tumour cells.
Topics: Animals; Bone Marrow; Carcinoma, Ehrlich Tumor; Chromosome Aberrations; Chromosomes; Cytarabine; Female; Injections, Intraperitoneal; Injections, Subcutaneous; Mechlorethamine; Mice; Mice, Inbred Strains | 1978 |
[Individual variations in the frequency of chromosome aberrations following exposure to chemical mutagens. III. Interindividual differences at different stages of the cell cycle].
Topics: Aziridines; Azirines; Cells, Cultured; Chromosome Aberrations; Chromosomes; Cytarabine; Genetic Variation; Mitosis; Morpholines; Mutagens; Thiotepa | 1976 |
[A cytological test system for the routine determination of mutagenicity].
Topics: Ascitic Fluid; Caffeine; Cells, Cultured; Chromosome Aberrations; Cytarabine; Hydrazines; Isonicotinic Acids; Mechlorethamine; Methods; Mutation; Netropsin | 1977 |
Clastogenic activity of cytosine arabinoside and 3'-deoxy-3'-fluorothymidine in Ehrlich ascites tumour cells in vitro.
Topics: Cell Line; Cell Survival; Chromosome Aberrations; Cytarabine; Dideoxynucleosides; Mitosis; Thymidine | 1976 |
Effects of inhibitors of DNA, RNA and protein synthesis on frequencies and types of premature chromosome condensation from X-ray induced micronuclei.
Topics: Azathioprine; Cell Nucleus; Chromosome Aberrations; Cytarabine; Dactinomycin; DNA; Ethidium; Humans; Mitosis; Puromycin; Radiation Genetics; RNA; Thymidine; Triaziquone; X-Rays | 1976 |
De novo appearance of the ph-1 chromosome in a previously monosomic bone marrow (45,XX,-6): conversion of a myeloproliferative disorder to acute myelogenous leukemia.
Topics: Adult; Alkaline Phosphatase; Blood Transfusion; Bone Marrow Cells; Bone Marrow Examination; Chromosome Aberrations; Chromosomes, Human, 21-22 and Y; Chromosomes, Human, 6-12 and X; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Female; Humans; Karyotyping; Leukemia, Myeloid, Acute; Leukocytes; Myeloproliferative Disorders; Prednisone; Vincristine | 1975 |
Blast crisis of chronic myeloid leukaemia: the effect of intensive chemotherapy.
Topics: Adolescent; Adult; Aged; Allopurinol; Antineoplastic Agents; Asparaginase; Chromosome Aberrations; Chromosomes, Human, 21-22 and Y; Cytarabine; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Prednisolone; Thioguanine; Vincristine | 1976 |
[Distribution of chromosome breakage point induced by arabinosylcytosine on in-vitro human lymphocytes].
Topics: Cells, Cultured; Chromatids; Chromosome Aberrations; Chromosomes; Cytarabine; Humans; In Vitro Techniques; Lymphocytes; Mitosis; Time Factors | 1976 |
Correlation between balance of specific chromosomes and expression of malignancy in hamster cells.
Topics: Animals; Animals, Newborn; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Chromosome Aberrations; Cricetinae; Cytarabine; Fibrosarcoma; Karyotyping; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosamines; Transplantation, Homologous | 1975 |
Ph1-positive megakaryoblastic leukemia.
Topics: Acute Disease; Autoradiography; Blood Cell Count; Blood Platelets; Bone Marrow; Carmustine; Chromosome Aberrations; Chromosomes, Human, 16-18; Chromosomes, Human, 19-20; Chromosomes, Human, 21-22 and Y; Chromosomes, Human, 6-12 and X; Cytarabine; Female; Humans; Lymph Nodes; Megakaryocytes; Middle Aged; Mitosis; Pneumonia; Thioguanine; Thrombocythemia, Essential; Vincristine | 1975 |
[Cytogenetic effect of mitomycin C and cytosine arabinoside on mice of different genotypes].
Topics: Animals; Bone Marrow; Bone Marrow Cells; Chromosome Aberrations; Cytarabine; Dose-Response Relationship, Drug; Genotype; Male; Mice; Mice, Inbred Strains; Mitomycins; Time Factors | 1975 |
The yield of fission neutron-induced chromatid aberrations in G2-stage human lymphocytes: effect of caffeine, hydroxyurea and cytosine arabinoside post-irradiation.
Topics: Caffeine; Chromosome Aberrations; Cytarabine; DNA Damage; DNA Repair; G2 Phase; Humans; Hydroxyurea; Lymphocytes; Neutrons | 1992 |
Evidence for an altered kinetics of DNA excision-repair in cells infected by herpes simplex virus type 1.
Topics: Animals; Aphidicolin; Chromosome Aberrations; Cytarabine; DNA Damage; DNA Repair; HeLa Cells; Humans; Kinetics; L Cells; Mice; Simplexvirus; Ultraviolet Rays | 1992 |
Effect of sampling time on chromosome aberration yield for 7 chemicals in Chinese hamster ovary cells.
Topics: Aminobiphenyl Compounds; Animals; Cadmium; Cadmium Compounds; Cell Count; CHO Cells; Chromosome Aberrations; Cricetinae; Cytarabine; Doxorubicin; Eugenol; Mutagenicity Tests; Mutagens; Phenylenediamines; Sulfates; Time Factors | 1992 |
[Countermeasure for treatment of leukemia in the aged].
Topics: Aged; Chromosome Aberrations; Creatinine; Cytarabine; Drug Therapy, Combination; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Middle Aged; Vincristine | 1992 |
Acute myeloid leukemia (AML) in Down's syndrome is highly responsive to chemotherapy: experience on Pediatric Oncology Group AML Study 8498.
Topics: Acute Disease; Adolescent; Adult; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Azacitidine; Child; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Daunorubicin; Down Syndrome; Etoposide; Female; Follow-Up Studies; Humans; Leukemia, Myeloid; Male; Mercaptopurine; Methotrexate; Prednisone; Remission Induction; Thioguanine; Vincristine | 1992 |
A predictive model for the clinical response to low dose ara-C: a study of 102 patients with myelodysplastic syndromes or acute leukaemia.
Topics: Aged; Aged, 80 and over; Anemia, Sideroblastic; Bone Marrow; Chromosome Aberrations; Cytarabine; Female; Humans; Karyotyping; Leukemia, Myeloid, Acute; Male; Myelodysplastic Syndromes; Platelet Count; Predictive Value of Tests | 1992 |
Disappearance of a highly unusual clone, 46,XY,del(7)(p12),t(9;22)(q34;q11) in chronic myeloid leukemia after treatment with recombinant interferon and cytosine arabinoside.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosome Banding; Chromosome Deletion; Chromosomes, Human, Pair 22; Chromosomes, Human, Pair 7; Chromosomes, Human, Pair 9; Cytarabine; Gene Deletion; Humans; Interferon-alpha; Karyotyping; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Recombinant Proteins; Translocation, Genetic | 1992 |
Proof of differentiative mode of action of all-trans retinoic acid in acute promyelocytic leukemia using X-linked clonal analysis.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Blotting, Southern; Bone Marrow; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Clone Cells; Cytarabine; Daunorubicin; DNA, Neoplasm; Etoposide; Female; Genetic Linkage; Humans; Leukemia, Promyelocytic, Acute; Translocation, Genetic; Tretinoin; X Chromosome | 1992 |
Acute myelomonocytic leukaemia and 48,XXY, +8 chromosome anomalies.
Topics: Antigens, CD; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Bacteremia; Chromosome Aberrations; Chromosomes, Human, Pair 8; Cytarabine; Daunorubicin; Genes, ras; Humans; Leukemia, Myelomonocytic, Acute; Male; Middle Aged; Thioguanine; Trisomy; X Chromosome | 1992 |
Prognostic impact of karyotype and immunologic phenotype in 125 adult patients with de novo AML.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cytarabine; Daunorubicin; Female; Humans; Immunophenotyping; Leukemia, Myeloid; Male; Middle Aged; Prognosis; Remission Induction; Survival Analysis | 1992 |
Molecular characterization of mutations at the hprt locus in V79 Chinese hamster cells induced by bleomycin in the presence of inhibitors of DNA repair.
Topics: Animals; Benzamides; Bleomycin; Blotting, Southern; Cell Line; Chromosome Aberrations; Cricetinae; Cricetulus; Cytarabine; Dideoxynucleosides; DNA Damage; DNA Repair; Hypoxanthine Phosphoribosyltransferase; Mutagens; Mutation; Nucleic Acid Hybridization | 1991 |
Isolation and characterization of a 1-beta-D-arabinofuranosylcytosine-resistant Chinese hamster ovary cell mutant that is also X-ray sensitive and is noncomplementary with ataxia telangiectasia cells.
Topics: Animals; Ataxia Telangiectasia; Cell Survival; CHO Cells; Chromosome Aberrations; Cricetinae; Cytarabine; DNA Repair; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Resistance; Genetic Complementation Test; Sister Chromatid Exchange; X-Rays | 1992 |
Radiation-induced chromatid aberrations in Cockayne syndrome and xeroderma pigmentosum group C fibroblasts in relation to cancer predisposition.
Topics: Causality; Cells, Cultured; Chromatids; Chromosome Aberrations; Cockayne Syndrome; Cytarabine; DNA Repair; Humans; In Vitro Techniques; Neoplasms; X-Rays; Xeroderma Pigmentosum | 1991 |
Cytogenetic and clonal culture evaluation after response to low dose Ara-C in myelodysplastic syndromes.
Topics: Adolescent; Adult; Aged; Bone Marrow; Cells, Cultured; Chromosome Aberrations; Cytarabine; Female; Hematopoiesis; Hematopoietic Stem Cells; Humans; Karyotyping; Male; Middle Aged; Myelodysplastic Syndromes; Remission Induction | 1991 |
Clastogenic action of ellipticine over the cell cycle of human lymphocytes and influence of posttreatments with caffeine and ara-C at G2.
Topics: Caffeine; Cell Cycle; Chromosome Aberrations; Cytarabine; DNA; DNA Repair; Drug Synergism; Ellipticines; G2 Phase; Humans; Mutagens; Sister Chromatid Exchange | 1991 |
Cytosine arabinoside enhancement of gamma irradiation induced mutations in human T-lymphocytes.
Topics: Cells, Cultured; Chromosome Aberrations; Cytarabine; DNA; DNA Damage; DNA Repair; Dose-Response Relationship, Radiation; Drug Resistance; Gamma Rays; Gene Frequency; Humans; Mutation; T-Lymphocytes; Thioguanine | 1991 |
Substrate-specific deoxycytidine kinase deficiency in 1-beta-D-arabinofuranosylcytosine-resistant leukemic cells.
Topics: Animals; Cell Survival; Chromosome Aberrations; Cytarabine; Deoxycytidine Kinase; Deoxyribonucleotides; Drug Resistance; Isoenzymes; Leukemia, Myeloid; Rats; Rats, Inbred BN; Substrate Specificity; Tumor Cells, Cultured | 1990 |
Chromosome-type exchange aberrations are induced by inhibiting repair of UVC-induced DNA lesions in quiescent human lymphocytes.
Topics: Chromosome Aberrations; Cytarabine; DNA Repair; Dose-Response Relationship, Radiation; Humans; In Vitro Techniques; Lymphocytes; Resting Phase, Cell Cycle; Ultraviolet Rays; X-Rays | 1990 |
On the time course of the interactions between DNA breaks in the production of a radiation-induced chromosome exchange aberration.
Topics: Chromosome Aberrations; Cytarabine; DNA; DNA Damage; DNA Repair; Half-Life; Humans; In Vitro Techniques; Lymphocytes; Mitosis; Time Factors; X-Rays | 1990 |
A complex chromosomal rearrangement and congenital anomalies in the progeny of a mother treated for childhood leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 12; Cytarabine; Humans; Infant, Newborn; Leukemia, Myeloid, Acute; Male; Prednisone; Vincristine | 1990 |
T-cell acute lymphoblastic leukemia with t(1;18)(p36;q22).
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Chromosome Aberrations; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 18; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Humans; Leukemia-Lymphoma, Adult T-Cell; Male; Prednisone; Thioguanine; Vincristine | 1990 |
Biochemical and cytogenetical characterization of Chinese hamster ovary X-ray-sensitive mutant cells xrs 5 and xrs 6. VI. The correlation between UV-induced DNA lesions and chromosomal aberrations, and their modulations with inhibitors of DNA repair synth
Topics: Animals; Cell Line; Chromosome Aberrations; Cricetinae; Cricetulus; Cytarabine; DNA; DNA Damage; DNA Repair; DNA Replication; DNA, Single-Stranded; Hydroxyurea; Mutation; Radiation Tolerance; Ultraviolet Rays; X-Rays | 1990 |
G2 effects of DNA-repair inhibitors on chromatid-type aberrations in root-tip cells treated with maleic hydrazide and mitomycin C.
Topics: Caffeine; Cell Cycle; Chromosome Aberrations; Chromosomes; Cytarabine; DNA Damage; DNA Repair; Floxuridine; Hydroxyurea; In Vitro Techniques; Interphase; Maleic Hydrazide; Mitomycin; Mitomycins; Plants; Pyridazines; Thymidine | 1989 |
The production of chromosomal alterations in human lymphocytes by drugs known to interfere with the activity of DNA topoisomerase II. I. m-AMSA.
Topics: Amsacrine; Cell Cycle; Cells, Cultured; Chromosome Aberrations; Chromosomes; Culture Media; Cytarabine; DNA Repair; Humans; Hydroxyurea; In Vitro Techniques; Lymphocytes; Sister Chromatid Exchange; Topoisomerase II Inhibitors; X-Rays | 1989 |
Relationship between cell cycle stage in the fertilized egg of mice and repair capacity for X-ray-induced damage in the sperm.
Topics: Animals; Benzamides; Caffeine; Cell Cycle; Chromosome Aberrations; Cytarabine; DNA Damage; DNA Repair; Hydroxyurea; Male; Metaphase; Mice; Radiation-Sensitizing Agents; Spermatozoa; Zygote | 1989 |
[Relation of karyotypic findings to chemotherapy response in patients with preleukemia].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Chromosome Aberrations; Chromosomes, Human, Pair 5; Chromosomes, Human, Pair 7; Cytarabine; Female; Humans; Male; Middle Aged; Myelodysplastic Syndromes; Preleukemia | 1989 |
Cytogenetic response of normal human and ataxia telangiectasia G2 cells exposed to X-rays and ara C.
Topics: Ataxia Telangiectasia; Cell Line; Chromosome Aberrations; Cytarabine; Fibroblasts; Humans; Interphase; Kinetics; Sister Chromatid Exchange; Vidarabine | 1989 |
Mechanism of chromosome aberration induction in the mouse egg fertilized with sperm recovered from postmeiotic germ cells treated with methyl methanesulfonate.
Topics: Animals; Benzamides; Caffeine; Chromosome Aberrations; Cytarabine; Female; Hydroxyurea; Male; Meiosis; Methyl Methanesulfonate; Mice; Mice, Inbred Strains; Mutagens; Ovum; Sister Chromatid Exchange; Spermatozoa; Zygote | 1989 |
Refractory anemia with excess of blasts in transformation hematologic and clinical study of 52 patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anemia, Refractory, with Excess of Blasts; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Bone Marrow; Bone Marrow Transplantation; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, Pair 5; Chromosomes, Human, Pair 8; Combined Modality Therapy; Cytarabine; Female; Humans; Karyotyping; Male; Middle Aged; Remission Induction | 1989 |
[Therapy of the preleukemic state: effect of androgens on refractory anemia].
Topics: Adult; Aged; Androgens; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Blast Crisis; Cholecalciferol; Chromosome Aberrations; Cytarabine; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Preleukemia; Prognosis | 1988 |
Repair capacity of fertilized mouse eggs for X-ray damage induced in sperm and mature oocytes.
Topics: Animals; Benzamides; Caffeine; Chromosome Aberrations; Chromosome Banding; Cleavage Stage, Ovum; Cytarabine; DNA Repair; Male; Mice; Mitotic Index; Oocytes; Spermatozoa; X-Rays | 1989 |
High-dose cytosine arabinoside and daunorubicin as primary therapy in elderly patients with acute myelogenous leukemia. A phase I-II study of the Southeastern Cancer Study Group.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemical and Drug Induced Liver Injury; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Evaluation; Female; Humans; Infections; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction | 1989 |
Effects of caffeine and inhibitors of DNA synthesis on chromatid-type aberrations induced by acetaldehyde in root-tip cells.
Topics: Acetaldehyde; Caffeine; Cells, Cultured; Chromatids; Chromosome Aberrations; Cytarabine; DNA Replication; Floxuridine; Hydroxyurea; Mutagenicity Tests; Plants | 1987 |
Modulation of mutagen-induced biological effects by inhibitors of DNA repair.
Topics: Alkylating Agents; Benzamides; Chromosome Aberrations; Cytarabine; DNA; DNA Polymerase II; DNA Repair; Drug Interactions; Drug Synergism; Humans; Lymphocytes; Mutagens; Mutation; Poly(ADP-ribose) Polymerase Inhibitors; Sister Chromatid Exchange | 1986 |
Qualitative differences between replicative and repair synthesis of DNA in normal and transformed mouse cells as measured by precursor discrimination.
Topics: Animals; Aphidicolin; Bromodeoxyuridine; Cell Line; Cell Transformation, Neoplastic; Chromosome Aberrations; Cytarabine; Deoxycytidine; Diterpenes; DNA; DNA Damage; DNA Polymerase II; DNA Repair; DNA Replication; Embryo, Mammalian; Mice; Substrate Specificity; Ultraviolet Rays | 1986 |
Different effects of 1-beta-D-arabinofuranosylcytosine and aphidicolin in S-phase cells--chromosome aberrations, cell-cycle delay and cytotoxicity.
Topics: Animals; Aphidicolin; Cell Cycle; Cell Line; Cell Survival; Chromosome Aberrations; Cytarabine; Diterpenes; DNA; DNA Replication; Drug Administration Schedule; Interphase; Macropodidae | 1987 |
Folate- and deoxyuridine-sensitive chromatid breakage may result from DNA repair during G2.
Topics: Aphidicolin; Chromosome Aberrations; Chromosome Fragility; Cytarabine; Deoxyuridine; Diterpenes; DNA Repair; Folic Acid; Humans; In Vitro Techniques; Interphase; Lymphocytes; Uracil | 1987 |
Synergism of 1-beta-D-arabinofuranosylcytosine with itself and aphidicolin.
Topics: Aphidicolin; Cell Cycle; Cell Line; Chromosome Aberrations; Cytarabine; Diterpenes; DNA Repair; Drug Administration Schedule; Drug Synergism; Mutation | 1988 |
An investigation using inhibition of G2 repair of the molecular basis of lesions which result in chromosomal aberrations.
Topics: Animals; Aphidicolin; Cells, Cultured; Chromosome Aberrations; Cytarabine; Diterpenes; DNA Damage; DNA Repair; Interphase; Sister Chromatid Exchange; X-Rays | 1988 |
Suppressive effect of novobiocin on the frequency of chromosome-type aberrations induced by ara C in the G1 phase of human lymphocytes.
Topics: 4-Nitroquinoline-1-oxide; Adult; Age Factors; Child; Chromosome Aberrations; Cytarabine; Humans; Infant, Newborn; Interphase; Lymphocytes; Methyl Methanesulfonate; Novobiocin | 1988 |
[Effect of cytosine arabinoside on the cell cycle and level of radiation-induced chromosome anomalies in lymphocytes of mammals].
Topics: Animals; Cell Cycle; Chromosome Aberrations; Cytarabine; Deoxycytidine; Humans; Lymphocyte Activation; Lymphocytes; Rabbits; Swine; Time Factors | 1985 |
[Megakaryoblastic leukemia with hypodiploidy in a girl with trisomy 21].
Topics: Blood Platelets; Bone Marrow; Child, Preschool; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Down Syndrome; Female; Humans; Leukemia; Primary Myelofibrosis | 1985 |
Short remission durations in therapy-related leukemia despite cytogenetic complete responses to high-dose cytarabine.
Topics: Adult; Aged; Biopsy, Needle; Bone Marrow; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Remission Induction | 1988 |
[Abnormal karyotype, t(9;13)(q34;q12) in a patient with acute myelocytic leukemia].
Topics: Chromosome Aberrations; Chromosome Deletion; Chromosomes, Human, Pair 13; Chromosomes, Human, Pair 6; Chromosomes, Human, Pair 9; Cytarabine; Female; Humans; Karyotyping; Leukemia, Myeloid, Acute; Middle Aged; Remission Induction | 1988 |
Chromosomal analysis in mouse eggs fertilized in vitro with sperm exposed to ultraviolet light (UV) and methyl and ethyl methanesulfonate (MMS and EMS).
Topics: Animals; Caffeine; Cell Cycle; Chromosome Aberrations; Cytarabine; Ethyl Methanesulfonate; Female; Fertilization in Vitro; Male; Methyl Methanesulfonate; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Spermatozoa; Ultraviolet Rays; Zygote | 1988 |
Myelodysplastic syndromes in childhood. Report of 21 patients from Italy and West Germany.
Topics: Adolescent; Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Child; Child, Preschool; Chromosome Aberrations; Cytarabine; Female; Germany, West; Humans; Infant; Italy; Male; Myelodysplastic Syndromes | 1987 |
DNA-repair kinetics and the sensitivity of cells to X-ray-induced chromosome aberrations: a mouse myeloid leukemia cell line and normal mouse bone marrow cells.
Topics: Animals; Bone Marrow; Cell Cycle; Cell Line; Chromosome Aberrations; Cytarabine; DNA Repair; Leukemia, Myeloid, Acute; Mice; X-Rays | 1986 |
[Chromosomal abnormalities before and after chemotherapy in a case with erythroleukemia].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cytarabine; Daunorubicin; Humans; Karyotyping; Leukemia, Erythroblastic, Acute; Male; Mercaptopurine; Middle Aged; Prednisolone | 1986 |
Different response rates to low-dose cytosine arabinoside in acute myeloid leukemia subtypes.
Topics: Age Factors; Antigens, Neoplasm; Antigens, Surface; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid, Acute; Prognosis | 1987 |
Kinetics of the effect of ara C on chromosome aberration yield in irradiated human lymphocytes.
Topics: Chromosome Aberrations; Cytarabine; DNA Repair; Humans; Interphase; Lymphocyte Activation; Lymphocytes; Time Factors | 1986 |
[Mechanism of the formation of micronuclei in PHA-stimulated lymphocytes from human peripheral blood].
Topics: Cell Cycle; Cell Nucleolus; Chromosome Aberrations; Cytarabine; Gamma Rays; Humans; Lymphocytes; Microscopy, Electron; Phytohemagglutinins; Stimulation, Chemical; Time Factors | 1986 |
[Action of ethanol introduced into a culture of human lymphocytes on the cytogenetic effect of cytosine arabinoside].
Topics: Adult; Alcoholism; Cells, Cultured; Chromosome Aberrations; Cytarabine; Drug Synergism; Ethanol; Humans; Lymphocytes; Male; Metaphase | 1986 |
Immediate and repair induced DNA double strand breaks in mammalian cells.
Topics: Animals; Cell Line; Chromosome Aberrations; Cricetinae; Cricetulus; Cytarabine; DNA; DNA Repair; Kinetics; Lung; Micrococcal Nuclease | 1986 |
Mechanisms involved in the formation of mutagen-induced chromosome aberrations as determined by premature chromosome condensation.
Topics: Chromosome Aberrations; Cytarabine; Humans; In Vitro Techniques; Lymphocytes; Mutagenicity Tests; Mutagens | 1986 |
[Myelodysplastic syndromes].
Topics: Chromosome Aberrations; Cytarabine; Humans; Leukemia; Myelodysplastic Syndromes; Prognosis | 1986 |
Effects of repair inhibition in the G1 phase of clastogen-treated human lymphocytes on the frequencies of chromosome-type and chromatid-type aberrations and sister-chromatid exchanges.
Topics: Cell Cycle; Cells, Cultured; Chromosome Aberrations; Cytarabine; DNA Repair; Lymphocytes; Sister Chromatid Exchange | 1987 |
Major karyotypic abnormalities in a near-tetraploid erythroleukemia.
Topics: Bone Marrow; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Doxorubicin; Humans; Karyotyping; Leukemia, Erythroblastic, Acute; Male; Metaphase; Middle Aged; Polyploidy; Prognosis | 1985 |
Evolution of clinical studies with high-dose cytosine arabinoside at the M.D. Anderson Hospital.
Topics: Arabinofuranosylcytosine Triphosphate; Chromosome Aberrations; Cytarabine; Drug Evaluation; Drug Resistance; Half-Life; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Prognosis; Time Factors | 1985 |
Chronic myelogenous leukemia: a multivariate analysis of the associations of patient characteristics and therapy with survival.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Basophils; Blood Cell Count; Body Weight; Bone Marrow Cells; Busulfan; Chromosome Aberrations; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Combinations; Female; Hemoglobins; Humans; Hydroxyurea; Leukemia, Myeloid; Male; Middle Aged; Philadelphia Chromosome; Prednisone; Prognosis; Risk; Vincristine | 1985 |
[Sensitivity of the lymphocyte chromosomes of chronic alcoholism patients to mutagenic exposure].
Topics: Adult; Alcoholism; Antibiotics, Antineoplastic; Cells, Cultured; Chromosome Aberrations; Cytarabine; Humans; Lymphocytes; Male; Mitomycin; Mitomycins; Mutagens | 1985 |
Low-dose cytarabine: persistence of a clonal abnormality during complete remission of acute nonlymphocytic leukemia.
Topics: Acute Disease; Aged; Chromosome Aberrations; Clone Cells; Cytarabine; Humans; Leukemia; Male; Metaphase; Y Chromosome | 1986 |
The role of short-lived DNA lesions in the production of chromosome-exchange aberrations.
Topics: Cells, Cultured; Chromosome Aberrations; Chromosomes; Cytarabine; Depression, Chemical; DNA Repair; Dose-Response Relationship, Radiation; Humans; Lymphocytes; Ultraviolet Rays; X-Rays | 1986 |
The nature and repair of DNA lesions that lead to chromosomal aberrations induced by ionizing radiations.
Topics: Cells, Cultured; Chromosome Aberrations; Cytarabine; DNA; DNA Repair; Humans; Lymphocytes | 1986 |
Low-dose cytarabine: chromosomal findings suggesting its cytostatic as well as differentiating effect.
Topics: Aged; Bone Marrow; Cell Differentiation; Chromosome Aberrations; Cytarabine; Humans; Leukemia; Male | 1985 |
Study on the repair of the radioinduced lesions involved in the formation of chromosomal aberrations in G0 human lymphocytes after exposure to gamma-rays and fast neutrons.
Topics: Cell Cycle; Chromosome Aberrations; Cytarabine; DNA Repair; Fast Neutrons; Gamma Rays; Humans; Lymphocytes | 1985 |
Management of myelodysplastic syndromes.
Topics: Antineoplastic Agents; Bone Marrow Diseases; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Humans; Preleukemia | 1985 |
Treatment of preleukemic syndromes with continuous intravenous infusion of low-dose cytosine arabinoside.
Topics: Adult; Aged; Bone Marrow; Chromosome Aberrations; Colony-Forming Units Assay; Cytarabine; Drug Evaluation; Female; Hematopoiesis; Humans; Infusions, Parenteral; Male; Middle Aged; Preleukemia; Syndrome; Time Factors | 1985 |
Cytosine arabinoside is a potent clastogen and does not affect the repair of X-ray-induced chromosome fragments in unstimulated human lymphocytes.
Topics: Animals; Cells, Cultured; Chromosome Aberrations; Chromosomes; Cricetinae; Cricetulus; Cytarabine; DNA Repair; Female; Humans; Interphase; Lymphocytes; Mutation; Ovary; X-Rays | 1985 |
Biology of cell killing by 1-beta-D-arabinofuranosylcytosine and its relevance to molecular mechanisms of cytotoxicity.
Topics: Animals; Cell Division; Cell Survival; Cells, Cultured; Chromosome Aberrations; Cricetinae; Cricetulus; Cytarabine; Demecolcine; DNA Replication; Fluorometry; Metaphase; Time Factors | 1985 |
Effects of pre-treatment with sodium butyrate on the frequencies of X-ray-induced chromosomal aberrations in human peripheral blood lymphocytes.
Topics: Butyrates; Butyric Acid; Cell Cycle; Cells, Cultured; Chromatin; Chromosome Aberrations; Cytarabine; DNA Repair; Humans; In Vitro Techniques; Lymphocytes; X-Rays | 1985 |
Synergistic effect of herpes simplex virus and cytosine arabinoside on human chromosomes.
Topics: Autoradiography; Cell Line; Chromosome Aberrations; Chromosomes; Culture Techniques; Cytarabine; DNA; Genetics, Medical; Humans; Kidney; Lung; Nucleosides; Resorcinols; Simplexvirus; Staining and Labeling; Thymidine; Tritium | 1971 |
Chromatid breakage: differential effect of inhibitors of DNA synthesis during G 2 phase.
Topics: Animals; Azacitidine; Azaguanine; Cell Line; Chromatids; Chromosome Aberrations; Cricetinae; Cytarabine; Cytidine; DNA; DNA Nucleotidyltransferases; Hydroxyurea; Lung; Mitosis; Oxidoreductases; Pyridines; Ribonucleotides; Thiosemicarbazones; Triazines | 1972 |
Philadelphia-chromosome-positive preleukaemic state.
Topics: Adult; Blood Cell Count; Bone Marrow Cells; Bone Marrow Examination; Chromosome Aberrations; Cytarabine; Cytogenetics; Daunorubicin; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Male; Prednisone; Thioguanine; Vincristine | 1972 |
The mutagenic properties of the nucleosides of pyrimidine analogues in Drosophila melanogaster.
Topics: Animals; Antimetabolites; Bromodeoxyuridine; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Deoxyuridine; Drosophila; Floxuridine; Mutagens; Mutation; Nucleosides | 1966 |
The influence of inhibitors of macromolecular syntheses on capacity of herpes simplex virus to induce chromosomal damage.
Topics: Carcinoma; Cell Line; Chromosome Aberrations; Colchicine; Culture Media; Culture Techniques; Cytarabine; Dactinomycin; Deoxyribonucleases; DNA Replication; DNA, Viral; Genes; Genetics, Microbial; Humans; Karyotyping; L Cells; Laryngeal Neoplasms; Puromycin; RNA, Messenger; Simplexvirus; Statistics as Topic; Time Factors | 1971 |
Early events required for induction of chromosome abnormalities in human cells by herpes simplex virus.
Topics: Cell Line; Chromosome Aberrations; Culture Techniques; Cytarabine; Cytopathogenic Effect, Viral; Deoxyuridine; DNA Replication; DNA, Viral; Genetic Code; Genetics, Microbial; Humans; Interferons; Iodine; Karyotyping; Kidney; Newcastle disease virus; Simplexvirus; Vesicular stomatitis Indiana virus; Virus Replication | 1971 |
Chronic myelogenous leukemia presenting in blastic crisis.
Topics: Adolescent; Adult; Cell Transformation, Neoplastic; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 21-22 and Y; Cyclophosphamide; Cytarabine; Diagnosis, Differential; Female; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Vincristine | 1972 |
Cytogenetic studies during remission of blastic crisis in a patient with chronic myelocytic leukaemia.
Topics: Adult; Aneuploidy; Blood Cell Count; Blood Platelets; Busulfan; Chromosome Aberrations; Chromosomes, Human, 21-22 and Y; Cytarabine; Erythrocytes, Abnormal; Female; Hematocrit; Humans; Leukemia, Myeloid; Leukocyte Count; Remission, Spontaneous | 1973 |
Chromosomes and causation of human cancer and leukemia. IX. Prognostic and therapeutic value of chromosomal findings in acute myeloblastic leukemia.
Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Bone Marrow Cells; Carmustine; Chromosome Aberrations; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitosis; Nitrosourea Compounds; Prednisone; Prognosis; Thioguanine; Time Factors; Vincristine | 1974 |
Chronic granulocytic leukaemia: multiple-drug chemotherapy for acute transformation.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Asparaginase; Chromosome Aberrations; Chromosomes, Human, 21-22 and Y; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid; Male; Methotrexate; Middle Aged; Prednisolone; Thioguanine; Vincristine | 1974 |
[Age sensitivity of the chromosomes of human lymphocytes to the action of cytosine arabinoside at stage G 2 of the cell cycle].
Topics: Adult; Age Factors; Chromosome Aberrations; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Infant, Newborn; Lymphocytes; Male; Middle Aged; Mitosis | 1972 |
[Cysteine modification of the cytogenetic effect of cytosine arabinoside in a culture of human peripheral blood lymphocytes].
Topics: Cells, Cultured; Chromosome Aberrations; Cysteine; Cytarabine; Humans; Lymphocytes | 1973 |
Cytologic studies of tumors. L. clonal proliferation of four stemlines in three hematopoietic tissues of a patient with reticulosarcoma.
Topics: Bone Marrow; Bone Marrow Cells; Bone Marrow Examination; Chromosome Aberrations; Culture Techniques; Cyclophosphamide; Cytarabine; Female; Humans; Karyotyping; Lectins; Lymph Nodes; Lymphoma, Non-Hodgkin; Mercaptopurine; Middle Aged; Prednisolone; Trisomy; Vincristine | 1971 |
A cytogenetic study of acute erythroleukemia in children.
Topics: Adolescent; Bone Marrow Examination; Child; Chromosome Aberrations; Chromosomes, Human, 6-12 and X; Culture Techniques; Cytarabine; Cytogenetics; Female; Humans; Karyotyping; Lectins; Leukemia, Erythroblastic, Acute; Male; Mercaptopurine; Mosaicism | 1968 |
The DiGuglielmo syndrome revisited.
Topics: Bone Marrow Cells; Chromosome Aberrations; Cytarabine; DNA Replication; Friend murine leukemia virus; Heme; Humans; Iron; Leukemia, Erythroblastic, Acute; Terminology as Topic | 1969 |
Chromosomal aberrations in a case of erythroleukaemia.
Topics: Aneuploidy; Chromosome Aberrations; Cytarabine; Humans; Karyotyping; Leukemia, Erythroblastic, Acute; Male; Mercaptopurine; Middle Aged; Polyploidy; Prednisone | 1970 |
Cytogenetic studies and their clinical correlates in adults with acute leukemia.
Topics: Adolescent; Adult; Age Factors; Aneuploidy; Bone Marrow Cells; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 13-15; Chromosomes, Human, 16-18; Chromosomes, Human, 21-22 and Y; Chromosomes, Human, 6-12 and X; Cyclophosphamide; Cytarabine; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisone; Recurrence; Remission, Spontaneous; Vincristine | 1971 |
Fetal group C trisomy after cytosine arabinoside and thioguanine.
Topics: Abnormalities, Drug-Induced; Abortion, Therapeutic; Adult; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 6-12 and X; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Mosaicism; Pregnancy; Pregnancy Complications, Hematologic; Thioguanine; Trisomy | 1971 |
Chromosomal effects of arabinosylcytosine in a human diploid cell strain.
Topics: Cell Division; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Humans; In Vitro Techniques | 1965 |