cystobactamid-919-2 has been researched along with Bacterial-Infections* in 1 studies
1 other study(ies) available for cystobactamid-919-2 and Bacterial-Infections
Article | Year |
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Total Syntheses of Cystobactamids and Structural Confirmation of Cystobactamid 919-2.
The cystobactamids are a family of antibacterial natural products with unprecedented chemical scaffolds that are active against both Gram-positive and Gram-negative pathogens. Herein, we describe the first total synthesis of cystobactamid 919-2 from three fragments. Our convergent synthesis enabled both the confirmation of the correct structure and the determination of the absolute configuration of cystobactamid 919-2. Topics: Anti-Bacterial Agents; Asparagine; Bacteria; Bacterial Infections; Biological Products; Chemistry Techniques, Synthetic; Humans; Models, Molecular; Molecular Conformation; Nitro Compounds; Stereoisomerism | 2017 |