cystine and Pancreatic Neoplasms

cystine has been researched along with Pancreatic Neoplasms in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's3 (30.00)24.3611
2020's5 (50.00)2.80

Authors

AuthorsStudies
Duan, H; Ferri, V; Gambhir, SS; Goel, M; Hatami, N; Haywood, T; Iagaru, A; Kellow, R; Kimura, R; Nakamoto, R; Park, W; Rosenberg, J; Shen, B; Wardak, M1
DeNicola, GM; Hao, J; Hempel, N; Huang, C; Lan, C; Li, Y; Li, Z; Lin, S; Singh, PK; Sun, D; Sun, J; Trebak, M; Wang, H; Wang, X; Wu, L; Yang, S1
Andrade, LR; Badgley, MA; Decker, AR; DelGiorno, KE; Firl, CEM; Georgiou, G; Gu, W; Hirschhorn, T; Iuga, A; Kapilian, J; Kremer, DM; Lamb, C; Lee, HJ; Liu, T; Lyssiotis, CA; Ma, A; Manor, U; Maurer, HC; Olive, KP; Palermo, CF; Purohit, V; Sagalovskiy, IR; Sajjakulnukit, P; Sastra, SA; Seeley, ES; Stockwell, BR; Stone, E; Tolstyka, ZP; Wahl, GM; Zhang, L1
Cassim, S; Daher, B; Parks, S; Pouyssegur, J; Vucetic, M1
Andren, AC; Asara, JM; Badgley, MA; Carpenter, ES; Crawford, HC; Cusmano, N; Das, NK; di Magliano, MP; Gao, T; Halbrook, CJ; Hou, SW; Kerk, SA; Kremer, DM; Lin, L; Little, AC; Lyssiotis, CA; Magnuson, B; Mbah, NE; McBrayer, SK; Myers, A; Nelson, BS; Nwosu, ZC; Olive, KP; Palermo, CF; Ramos, J; Sajjakulnukit, P; Sastra, SA; Savani, MR; Shah, YM; Shan, M; Thurston, G; Wisner, S; Yarosz, EL; Zhang, L1
Denny, C; Federman, N; Girgis, MD; McCabe, KE; Nagy, JO; Rochefort, MM; Tomlinson, JS; Wu, AM1
Guerrero Gual, M; Michalopoulou Alevras, T; Pérez-Maraver, M; Villabona Artero, C1
Gout, PW; Ling, V; Lo, M; Wang, YZ1
Boytim, ML; Cohen, SJ; Conkling, P; Davis, P; Dorr, RT; Hersh, EM; Modiano, MR; Patt, YZ; Zalupski, MM1
Doi, K1

Trials

1 trial(s) available for cystine and Pancreatic Neoplasms

ArticleYear
A phase I study of imexon plus gemcitabine as first-line therapy for advanced pancreatic cancer.
    Cancer chemotherapy and pharmacology, 2010, Volume: 66, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Cohort Studies; Cystine; Deoxycytidine; Dose-Response Relationship, Drug; Female; Gemcitabine; Half-Life; Hexanones; Humans; Male; Middle Aged; Pancreatic Neoplasms; Sulfhydryl Compounds; Tomography, X-Ray Computed

2010

Other Studies

9 other study(ies) available for cystine and Pancreatic Neoplasms

ArticleYear
Pilot-phase PET/CT study targeting integrin α
    European journal of nuclear medicine and molecular imaging, 2022, Volume: 50, Issue:1

    Topics: Cystine; Cystine-Knot Miniproteins; Female; Humans; Male; Pancreatic Neoplasms; Peptides; Positron Emission Tomography Computed Tomography; Radiopharmaceuticals; Tissue Distribution

2022
Mitochondrial Calcium Uniporter Drives Metastasis and Confers a Targetable Cystine Dependency in Pancreatic Cancer.
    Cancer research, 2022, 06-15, Volume: 82, Issue:12

    Topics: Calcium; Calcium Channels; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cystine; Humans; Kelch-Like ECH-Associated Protein 1; NF-E2-Related Factor 2; Pancreatic Neoplasms

2022
Cysteine depletion induces pancreatic tumor ferroptosis in mice.
    Science (New York, N.Y.), 2020, 04-03, Volume: 368, Issue:6486

    Topics: Animals; Carcinoma, Pancreatic Ductal; Cationic Amino Acid Transporter 1; Cell Line, Tumor; Cystathionine gamma-Lyase; Cysteine; Cystine; Ferroptosis; Gene Deletion; Humans; Mice; Mice, Mutant Strains; Pancreatic Neoplasms

2020
Overcoming Therapeutic Challenges for Pancreatic Ductal Adenocarcinoma with xCT Inhibitors.
    Advances in experimental medicine and biology, 2021, Volume: 1301

    Topics: Carcinoma, Pancreatic Ductal; Cell Death; Cystine; Humans; Oxidation-Reduction; Pancreatic Neoplasms

2021
GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis.
    Nature communications, 2021, 08-11, Volume: 12, Issue:1

    Topics: Animals; Antioxidants; Aspartate Aminotransferase, Cytoplasmic; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cystine; Ferroptosis; Glutathione; Humans; Iron; Mice; Mitochondria; Pancreatic Neoplasms

2021
An engineered anti-CA19-9 cys-diabody for positron emission tomography imaging of pancreatic cancer and targeting of polymerized liposomal nanoparticles.
    The Journal of surgical research, 2013, Volume: 185, Issue:1

    Topics: Animals; Antibodies, Bispecific; CA-19-9 Antigen; Cell Line, Tumor; Cystine; Female; Humans; Immunotherapy; Liposomes; Mice; Mice, Nude; Multiple Myeloma; Nanoparticles; Pancreatic Neoplasms; Positron-Emission Tomography; Protein Engineering; Single-Chain Antibodies; Xenograft Model Antitumor Assays

2013
[Autoimmune hypoglycemia syndrome associated with α lipoic acid consumption].
    Medicina clinica, 2015, Jan-20, Volume: 144, Issue:2

    Topics: Alopecia; Antioxidants; Autoimmune Diseases; Cystine; Diagnosis, Differential; Dietary Supplements; Female; Humans; Hyperinsulinism; Hyperplasia; Hypoglycemia; Insulin; Insulinoma; Islets of Langerhans; Middle Aged; Pancreatic Neoplasms; Sulfhydryl Compounds; Thioctic Acid

2015
The xc- cystine/glutamate antiporter: a mediator of pancreatic cancer growth with a role in drug resistance.
    British journal of cancer, 2008, Aug-05, Volume: 99, Issue:3

    Topics: Amino Acid Transport System y+; Antineoplastic Agents; Base Sequence; Blotting, Western; Cell Line, Tumor; Cystine; Deoxycytidine; DNA Primers; Drug Resistance, Neoplasm; Gemcitabine; Glutathione; Humans; Immunohistochemistry; Microscopy, Fluorescence; Oxidative Stress; Pancreatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction

2008
[Studies on the mechanism of the diabetogenic activity of streptozotocin and on the ability of compounds to block the diabetogenic activity of streptozotocin (author's transl)].
    Nihon Naibunpi Gakkai zasshi, 1975, Mar-20, Volume: 51, Issue:3

    Topics: Adenoma, Islet Cell; Amides; Animals; Blood Glucose; Cats; Cystine; Deoxyglucose; Diabetes Mellitus; Dimethylnitrosamine; Fatty Acids, Nonesterified; Glutathione; Guinea Pigs; Insulin; Islets of Langerhans; Male; Mannoheptulose; Mice; NAD; Niacinamide; Nicotinic Acids; Pancreatic Neoplasms; Picolinic Acids; Pyrazinamide; Rabbits; Rats; Streptozocin; Tolbutamide; Uric Acid

1975