cystine and Neoplasms

cystine has been researched along with Neoplasms in 63 studies

Research

Studies (63)

TimeframeStudies, this research(%)All Research%
pre-199022 (34.92)18.7374
1990's4 (6.35)18.2507
2000's4 (6.35)29.6817
2010's14 (22.22)24.3611
2020's19 (30.16)2.80

Authors

AuthorsStudies
Du, J; Hu, W; Huang, Z; Li, Y; Tong, X; Wang, X; Wang, Y; Xia, J; Zhou, Y1
Biggin, PC; Deme, JC; Kolokouris, D; Kuteyi, G; Lea, SM; Newstead, S; Parker, JL1
Corley, RA; Crowell, SR; Madeen, EP; Ognibene, TJ; Pande, P; Smith, JN; Turteltaub, KW; Williams, DE1
Itahana, K; Itahana, Y; Lee, Y; Ong, CC1
Chen, K; He, J; Wang, J; Wang, X; Zhang, M1
Chen, L; Deng, L; Qin, S; Wang, G; Wang, P; Xia, C; Yao, J; Zheng, Y1
Dong, X; Song, X; Wang, C; Wang, L; Wang, W; Wang, X; Wu, H; Xu, H; Zhao, L1
Ackerman, HD; Caldwell, S; Combs, JA; DeNicola, GM; Falzone, A; Flores, ER; Prieto-Farigua, N; Yoon, SJ1
Bao, Y; Jin, Y; Su, Z; Wang, Z; Wu, X; Xu, H; Yan, R; Zhang, H; Zhang, Y1
Inoue, M; Ishida, H; Kawashiri, T; Kobayashi, D; Kudamatsu, H; Mine, K; Mori, K; Shimazoe, T; Tsuchiya, T; Uchida, M1
Matsuu-Matsuyama, M; Nakashima, M; Shichijo, K; Tsuchiya, T1
Gan, B; Hang, Q; Horbath, A; James You, M; Kondiparthi, L; Lei, G; Liu, X; Ma, L; Mao, C; Olszewski, K; Poyurovsky, MV; Teng, H; Wu, S; Yan, Y; Zhuang, L1
Ferreira Dos Santos, A; Friedmann Angeli, JP; Goding, CR; Hufnagel, A; Jessen, C; Kreß, JKC; Meierjohann, S; Mosteo, L; Schmitz, W; Xavier da Silva, TN1
Wang, Z1
Cormerais, Y; Pouysségur, J; Vucetic, M1
Delfarah, A; Graham, NA; Joly, JH; Parrish, S; Phung, PS1
Egashira, N; Kawashiri, T; Kobayashi, D; Shimazoe, T; Tsuchiya, T1
Chen, T; Lai, H; Liu, C1
Gan, B; Koppula, P; Zhuang, L1
Chen, J; Cheng, W; Fang, B; Gan, B; Koppula, P; Lee, H; Lei, G; Liu, X; Mao, C; Nie, L; Qian, SB; Swanda, RV; Wang, C; Xiao, Z; Zhang, J; Zhang, Y; Zhuang, L1
Chong, WY; Chung, LY; Imae, T; Kiew, LV; Lee, HB; Saw, WS; Sim, KS; Ujihara, M; Voon, SH1
Huang, BK; Langford, TF; Lim, JB; Moon, SJ; Sikes, HD1
Bogaerts, A; Ghasemitarei, M; Razzokov, J; Shokri, B; Yusupov, M1
Cai, A; Chen, R; Chen, Z; Ganapathy, V; Kou, L; Sun, R; Xiao, S; Yao, Q; Zheng, H; Zheng, Y1
Hogg, PJ1
Harris, HH; Weekley, CM1
Hanigan, MH1
Eli, M; Kong, B; Mamtimin, B; Turahun, A; Upur, H1
Chen, T; He, L; Lai, H1
Baer, R; Gu, W; Hibshoosh, H; Jiang, L; Kon, N; Li, T; Su, T; Wang, SJ1
Attardi, LD; Bieging, KT1
WHITE, FR; WHITE, J1
CLOWES, GH; HARRIS, PN; KRAHL, ME1
GREENSTEIN, JP; LEUTHARDT, FM1
Altschmied, J; Haendeler, J; Matsushima, S; Sadoshima, J; Shao, D; Zschauer, TC1
Barclay, AN; Metcalfe, C; Stegmann, M1
GIAMPAOLO, R; ROMANO, M; RUFFO, A1
DOMAGALLA, H; LEY, H1
SUHRLAND, LG; WEISBERGER, AS1
ALLARD, C; CANTE RO, A; DE LAMIRANDE, G1
ANDERSON, EI; STEKOL, JA; WEISS, S1
BELLION, B; RESEGOTTI, L1
SUGAR, EA1
WAKIZAKA, J; YUGE, S2
MICHEL, R; ROCHE, J1
BASERGA, R; LAYDE, JP1
REID, BL1
MUELLER, OH1
Bukowska, B1
Barbacioru, C; Dai, Z; Huang, Y; Sadée, W1
Dewey, VC; Kidder, GW1
Gout, PW; Lo, M; Wang, YZ1
Drexel, H; Kellner, K; Ley, H1
Bast, A; Bongers, V; Braakhuis, BJ; de Jong, J; de Vries, N; Snow, GB; Steen, I1
Breitkreutz, R; Drings, P; Dröge, W; Hack, V; Holm, E; Kinscherf, R; Schmid, D; Stahl-Henning, C; Taut, F1
Dröge, W; Holm, E1
Bärtsch, P; Benner, A; Breitkreutz, R; Dröge, W; Hack, V; Kinscherf, R; Röhrer, H; Taut, F1
Holt, JA1
Allison, AC1
Shapiro, HM1
Homolka, J1

Reviews

16 review(s) available for cystine and Neoplasms

ArticleYear
The amino acid transporter SLC7A11-mediated crosstalk implicated in cancer therapy and the tumor microenvironment.
    Biochemical pharmacology, 2022, Volume: 205

    Topics: Amino Acid Transport System y+; Cell Line, Tumor; Cystine; Doxorubicin; Glutamic Acid; Humans; Neoplasms; Tumor Microenvironment

2022
Targeting amino acids transporters (SLCs) to starve cancer cells to death.
    Biochemical and biophysical research communications, 2019, 12-17, Volume: 520, Issue:4

    Topics: Amino Acid Transport System ASC; Amino Acid Transport Systems; Amino Acids; Antioxidants; Cell Line, Tumor; Cystine; Gene Expression Regulation; Glutamic Acid; Humans; Large Neutral Amino Acid-Transporter 1; Metabolome; Minor Histocompatibility Antigens; Molecular Targeted Therapy; Neoplasms

2019
Cystine transporter SLC7A11/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy.
    Protein & cell, 2021, Volume: 12, Issue:8

    Topics: Amino Acid Transport System y+; Antineoplastic Agents; Cystine; DNA Methylation; Ferroptosis; Gene Expression Regulation, Neoplastic; Glucose; Glutamine; Glutathione; Histones; Humans; Molecular Targeted Therapy; Neoplasms; Piperazines; Signal Transduction; Sorafenib; Sulfasalazine

2021
Targeting allosteric disulphide bonds in cancer.
    Nature reviews. Cancer, 2013, Volume: 13, Issue:6

    Topics: Allosteric Regulation; Angiogenic Proteins; Animals; Cystine; Humans; Molecular Targeted Therapy; Neoplasms; Neovascularization, Pathologic; Oxidation-Reduction; Protein Processing, Post-Translational

2013
Which form is that? The importance of selenium speciation and metabolism in the prevention and treatment of disease.
    Chemical Society reviews, 2013, Dec-07, Volume: 42, Issue:23

    Topics: Clinical Trials as Topic; Cystine; Dietary Supplements; Histone Deacetylase Inhibitors; Humans; Neoplasms; Organoselenium Compounds; Reactive Oxygen Species; Selenium Compounds; Selenocysteine; Selenomethionine; Selenoproteins; Sulfhydryl Compounds

2013
Gamma-glutamyl transpeptidase: redox regulation and drug resistance.
    Advances in cancer research, 2014, Volume: 122

    Topics: Animals; Catalysis; Cystine; Drug Resistance, Neoplasm; gamma-Glutamyltransferase; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glutathione; Humans; Mice; Neoplasms; Oxidants; Oxidation-Reduction; Oxygen; Rats

2014
Interacting with thioredoxin-1--disease or no disease?
    Antioxidants & redox signaling, 2013, Mar-20, Volume: 18, Issue:9

    Topics: Animals; Atherosclerosis; Blood Vessels; Cardiovascular System; Cysteine; Cystine; Diabetes Mellitus, Type 2; Heart Diseases; Humans; Hydrogen Peroxide; Mice; Models, Cardiovascular; Molecular Targeted Therapy; Myocardium; NADP; Neoplasm Proteins; Neoplasms; Oxidation-Reduction; Peroxiredoxins; Reactive Oxygen Species; Signal Transduction; Thioredoxins

2013
Immunoregulation through membrane proteins modified by reducing conditions induced by immune reactions.
    European journal of immunology, 2013, Volume: 43, Issue:1

    Topics: Animals; Arthritis; Cystine; Cytokines; Hepacivirus; HIV; Humans; Membrane Proteins; Neoplasms; Oxidation-Reduction; Platelet Activation; Protein Conformation; Protein Disulfide-Isomerases; Virus Internalization

2013
[ON VARIOUS USES OF RADIOIODINE IN PHYSIOLOGY AND IN THYROID BIOCHEMISTRY].
    Annales de la nutrition et de l'alimentation, 1963, Volume: 17

    Topics: Adenosine Triphosphate; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Chromatography; Cystine; Diiodotyrosine; Dogs; Glucuronates; Iodine Isotopes; Iodine Radioisotopes; Kidney; Leucine; Liver; Metabolism; Mitochondria; Neoplasms; Rats; Research; Sodium Isotopes; Sulfur Isotopes; Thyroid Gland; Thyroid Hormones; Thyroidectomy; Thyroxine; Triiodothyronine; Valine

1963
[Glutathione: its biosynthesis, induction agents and concentrations in selected diseases].
    Medycyna pracy, 2004, Volume: 55, Issue:6

    Topics: Animals; Cysteine; Cystine; Glutamic Acid; Glutathione; Glycine; Humans; Male; Neoplasms

2004
The x(c)- cystine/glutamate antiporter: a potential target for therapy of cancer and other diseases.
    Journal of cellular physiology, 2008, Volume: 215, Issue:3

    Topics: Amino Acid Transport Systems; Animals; Antiporters; Cystine; Glutamic Acid; Humans; Neoplasms

2008
Role of cysteine and glutathione in HIV infection and other diseases associated with muscle wasting and immunological dysfunction.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1997, Volume: 11, Issue:13

    Topics: Animals; CD4-Positive T-Lymphocytes; Colitis, Ulcerative; Crohn Disease; Cysteine; Cystine; Fatigue Syndrome, Chronic; Glutamine; Glutathione; HIV Wasting Syndrome; Humans; Killer Cells, Natural; Models, Biological; Muscle, Skeletal; Muscular Diseases; Neoplasms; Sepsis; Wasting Syndrome; Wounds and Injuries

1997
Lysosomes and the responses of cells to toxic materials.
    The Scientific basis of medicine annual reviews, 1968

    Topics: Asbestosis; Beryllium; Crystallography; Cystine; Foreign Bodies; Gout; Lysosomes; Macrophages; Neoplasms; Silicon Dioxide; Silicosis

1968
Redox balance in the body: an approach to quantitation.
    The Journal of surgical research, 1972, Volume: 13, Issue:3

    Topics: Acid-Base Equilibrium; Acidosis; Alkalosis; Ascorbic Acid; Cell Division; Cell Membrane; Cystine; Cytosol; Electron Transport; Galactose; Glucose; Glutathione; Homeostasis; Humans; Hypoxia; Lactates; Lysosomes; Mitochondria; NAD; Neoplasms; Oxidation-Reduction; Oxygen Consumption; Proteins; Pyruvates; Sulfhydryl Compounds

1972
Selenium and cancer.
    Nutrition reviews, 1970, Volume: 28, Issue:3

    Topics: Adult; Animals; Carcinogens; Cystine; Depression, Chemical; Food Analysis; Humans; Male; Neoplasms; Precancerous Conditions; Purines; Rats; Selenium; Sodium; Time Factors

1970
Polarography of proteins, analytical principles and applications in biological and clinical chemistry.
    Methods of biochemical analysis, 1971, Volume: 19

    Topics: Adult; Blood Proteins; Cathepsins; Cerebrospinal Fluid Proteins; Chemistry, Clinical; Cobalt; Cysteine; Cystine; Disease; Electrophoresis; Enzyme Precursors; Globulins; Humans; Hydroxides; Infant; Infant, Newborn; Mathematics; Methods; Mucoproteins; Neoplasms; Pepsin A; Peptide Hydrolases; Polarography; Potassium; Protein Denaturation; Proteins; Proteinuria; Serum Albumin; Temperature; Trypsin; Trypsin Inhibitors

1971

Trials

1 trial(s) available for cystine and Neoplasms

ArticleYear
The redox state as a correlate of senescence and wasting and as a target for therapeutic intervention.
    Blood, 1998, Jul-01, Volume: 92, Issue:1

    Topics: Acetylcysteine; Adolescent; Adult; Aged; Aged, 80 and over; Aging; Cell Death; Child; Child, Preschool; Cystine; Female; Free Radical Scavengers; Humans; Male; Middle Aged; Neoplasms; Oxidation-Reduction; Serum Albumin; Sulfhydryl Compounds

1998

Other Studies

46 other study(ies) available for cystine and Neoplasms

ArticleYear
CISD3 inhibition drives cystine-deprivation induced ferroptosis.
    Cell death & disease, 2021, 09-08, Volume: 12, Issue:9

    Topics: Animals; Cell Line, Tumor; Cell Survival; Cystine; Disease Progression; Ferroptosis; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glutamine; Homeostasis; Humans; Iron; Iron-Sulfur Proteins; Lipid Peroxides; Mice, Nude; Mitochondria; Mitochondrial Dynamics; Mitochondrial Proteins; Mitophagy; Neoplasms; Organophosphorus Compounds; Piperazines; Ubiquinone; Xenograft Model Antitumor Assays

2021
Molecular basis for redox control by the human cystine/glutamate antiporter system xc
    Nature communications, 2021, 12-08, Volume: 12, Issue:1

    Topics: Amino Acid Transport System y+; Antiporters; Biochemistry; Cryoelectron Microscopy; Cysteine; Cystine; Fusion Regulatory Protein 1, Heavy Chain; Glutamic Acid; Glutathione; HEK293 Cells; Humans; Neoplasms; Oxidation-Reduction; Reactive Oxygen Species; Up-Regulation

2021
Translating dosimetry of Dibenzo[def,p]chrysene (DBC) and metabolites across dose and species using physiologically based pharmacokinetic (PBPK) modeling.
    Toxicology and applied pharmacology, 2022, 03-01, Volume: 438

    Topics: Animals; Carcinogens; Chrysenes; Cystine; Female; Humans; Male; Mice; Models, Biological; Neoplasms

2022
Redox-dependent AMPK inactivation disrupts metabolic adaptation to glucose starvation in xCT-overexpressing cancer cells.
    Journal of cell science, 2022, 08-01, Volume: 135, Issue:15

    Topics: Amino Acid Transport System y+; AMP-Activated Protein Kinases; Cell Line, Tumor; Cystine; Glucose; Glutamic Acid; Neoplasms; Oxidation-Reduction

2022
Cystine Induced-mTORC2 Activation through Promoting Sin1 Phosphorylation to Suppress Cancer Cell Ferroptosis.
    Molecular nutrition & food research, 2022, Volume: 66, Issue:23

    Topics: Adaptor Proteins, Signal Transducing; Cystine; Ferroptosis; Mechanistic Target of Rapamycin Complex 1; Mechanistic Target of Rapamycin Complex 2; Multiprotein Complexes; Neoplasms; Phosphorylation; Proto-Oncogene Proteins c-akt; TOR Serine-Threonine Kinases

2022
Potent nanoreactor-mediated ferroptosis-based strategy for the reversal of cancer chemoresistance to Sorafenib.
    Acta biomaterialia, 2023, 03-15, Volume: 159

    Topics: Cystine; Drug Resistance, Neoplasm; Ferroptosis; Fusion Regulatory Protein 1, Heavy Chain; Glutathione; Humans; Nanotechnology; Neoplasms; Phospholipid Hydroperoxide Glutathione Peroxidase; Sorafenib

2023
Comprehensive Metabolic Tracing Reveals the Origin and Catabolism of Cysteine in Mammalian Tissues and Tumors.
    Cancer research, 2023, 05-02, Volume: 83, Issue:9

    Topics: Animals; Carcinogenesis; Cysteine; Cystine; Glutathione; Mammals; Mice; Neoplasms; Serine

2023
Cu
    International journal of pharmaceutics, 2023, Jun-10, Volume: 640

    Topics: Animals; Cell Line, Tumor; Cystine; Glutathione; Hyaluronic Acid; Hydrogen Peroxide; Immunotherapy; Mice; Nanoparticles; Neoplasms; Photochemotherapy; Reactive Oxygen Species; Schiff Bases; Tumor Microenvironment

2023
Ameliorating effects of cystine and theanine in a cancer cachexia mouse model.
    Journal of pharmacological sciences, 2023, Volume: 152, Issue:3

    Topics: Cachexia; Cystine; Humans; Neoplasms; Weight Loss

2023
The effects of cystine and theanine mixture on the chronic survival rate and tumor incidence of rats after total body X-ray irradiation†.
    Journal of radiation research, 2023, Jul-18, Volume: 64, Issue:4

    Topics: Animals; Cystine; Glutathione; Incidence; Male; Neoplasms; Rats; Rats, Wistar; Survival Rate; Whole-Body Irradiation; X-Rays

2023
SLC7A11 expression level dictates differential responses to oxidative stress in cancer cells.
    Nature communications, 2023, 06-21, Volume: 14, Issue:1

    Topics: Amino Acid Transport System y+; Cell Line, Tumor; Cystine; Disulfides; Hydrogen Peroxide; Neoplasms; Oxidative Stress

2023
The integrated stress response effector ATF4 is an obligatory metabolic activator of NRF2.
    Cell reports, 2023, 07-25, Volume: 42, Issue:7

    Topics: Activating Transcription Factor 4; Cystine; Glutathione; Humans; Neoplasms; NF-E2-Related Factor 2; Oxidative Stress

2023
Lysosomal cystine controls ferroptosis in cancer.
    Nature cell biology, 2023, Volume: 25, Issue:10

    Topics: Cystine; Ferroptosis; Humans; Lysosomes; Neoplasms

2023
A synthetic lethal drug combination mimics glucose deprivation-induced cancer cell death in the presence of glucose.
    The Journal of biological chemistry, 2020, 01-31, Volume: 295, Issue:5

    Topics: Amino Acid Transport System y+; Antineoplastic Combined Chemotherapy Protocols; Antiporters; Cell Death; Cell Line, Tumor; Cell Survival; Cysteine; Cystine; Dimerization; Glucose; Glucose Transporter Type 1; Glutamic Acid; Glutathione; Humans; Metabolome; NADP; Neoplasms; Oxidation-Reduction; Reactive Oxygen Species; Synthetic Drugs

2020
Oral administration of Cystine and Theanine ameliorates oxaliplatin-induced chronic peripheral neuropathy in rodents.
    Scientific reports, 2020, 07-29, Volume: 10, Issue:1

    Topics: Administration, Oral; Animals; Cold Temperature; Cystine; Disease Models, Animal; Drug Therapy, Combination; Glutamates; Glutathione; Hyperalgesia; Male; Mice; Neoplasms; Oxaliplatin; PC12 Cells; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Sciatic Nerve

2020
Boosting Natural Killer Cell-Based Cancer Immunotherapy with Selenocystine/Transforming Growth Factor-Beta Inhibitor-Encapsulated Nanoemulsion.
    ACS nano, 2020, 09-22, Volume: 14, Issue:9

    Topics: Cell Line, Tumor; Cystine; Humans; Immunotherapy; Killer Cells, Natural; Neoplasms; Organoselenium Compounds; Transforming Growth Factor beta; Transforming Growth Factors

2020
mTORC1 couples cyst(e)ine availability with GPX4 protein synthesis and ferroptosis regulation.
    Nature communications, 2021, 03-11, Volume: 12, Issue:1

    Topics: Amino Acid Transport System y+; Cell Line, Tumor; Cysteine; Cystine; Ferroptosis; Gene Knockout Techniques; Glutathione; HEK293 Cells; Humans; Mechanistic Target of Rapamycin Complex 1; Neoplasms; Phospholipid Hydroperoxide Glutathione Peroxidase

2021
Size-dependent effect of cystine/citric acid-capped confeito-like gold nanoparticles on cellular uptake and photothermal cancer therapy.
    Colloids and surfaces. B, Biointerfaces, 2018, Jan-01, Volume: 161

    Topics: Cell Line, Tumor; Cell Survival; Citric Acid; Cystine; Endocytosis; Gold; Humans; Metal Nanoparticles; Microscopy, Electron; Neoplasms; Particle Size; Phototherapy

2018
Monitoring the action of redox-directed cancer therapeutics using a human peroxiredoxin-2-based probe.
    Nature communications, 2018, 08-07, Volume: 9, Issue:1

    Topics: Antioxidants; Auranofin; Cystine; Cytoplasm; Cytosol; Dioxolanes; Fluorescent Dyes; HEK293 Cells; Humans; Hydrogen Peroxide; Neoplasms; Organoselenium Compounds; Oxidants; Oxidation-Reduction; Oxidative Stress; Peroxiredoxins; Signal Transduction; Thioredoxins

2018
Transport of cystine across xC
    Archives of biochemistry and biophysics, 2019, 03-30, Volume: 664

    Topics: Alanine; Amino Acid Substitution; Amino Acid Transport System y+; Antiporters; Arginine; Binding Sites; Cystine; Humans; Molecular Dynamics Simulation; Neoplasms; Protein Transport

2019
Ambidextrous Approach To Disrupt Redox Balance in Tumor Cells with Increased ROS Production and Decreased GSH Synthesis for Cancer Therapy.
    ACS applied materials & interfaces, 2019, Jul-31, Volume: 11, Issue:30

    Topics: Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cysteine; Cystine; Glutathione; Humans; Nanoparticles; Neoplasms; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Sulfasalazine; Zinc Oxide

2019
[Plasma amino acid profiling of "same symptom for different disease" in Uyghur medicine based on high-performance liquid chromatography].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2014, Volume: 39, Issue:6

    Topics: Amino Acids; Arginine; Aspartic Acid; Chromatography, High Pressure Liquid; Cystine; Humans; Isoleucine; Leucine; Medicine, Chinese Traditional; Neoplasms; Serine; Tyrosine; Valine

2014
Dual-function nanosystem for synergetic cancer chemo-/radiotherapy through ROS-mediated signaling pathways.
    Biomaterials, 2015, Volume: 51

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cystine; DNA Damage; Drug Delivery Systems; Humans; Intracellular Space; Male; Mice, Inbred ICR; Mice, Nude; Nanoparticles; Neoplasms; Nitrogen; Organoselenium Compounds; Photoelectron Spectroscopy; Porosity; Radiography; Reactive Oxygen Species; Signal Transduction; Silicon Dioxide; tat Gene Products, Human Immunodeficiency Virus; Transferrin; X-Rays; Xenograft Model Antitumor Assays

2015
Ferroptosis as a p53-mediated activity during tumour suppression.
    Nature, 2015, Apr-02, Volume: 520, Issue:7545

    Topics: Amino Acid Transport System y+; Animals; Biological Transport; Cell Death; Cystine; Embryo, Mammalian; Embryonic Development; Humans; Iron; Mice; Neoplasms; Oxidative Stress; Proto-Oncogene Proteins c-mdm2; Reactive Oxygen Species; Substrate Specificity; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays

2015
Cancer: A piece of the p53 puzzle.
    Nature, 2015, Apr-02, Volume: 520, Issue:7545

    Topics: Animals; Cystine; Humans; Iron; Neoplasms; Reactive Oxygen Species; Tumor Suppressor Protein p53

2015
Effect of cystine per se on the formation of hepatomas in rats following the ingestion of p-dimethylamino-azobenzene.
    Journal of the National Cancer Institute, 1946, Volume: 7, Issue:2

    Topics: Animals; Azo Compounds; Carcinoma, Hepatocellular; Cystine; Liver Neoplasms; Neoplasms; Rats

1946
p-Dimethylaminoazobenzene carcinogenesis with purified diets varying in content of cysteine, cystine, liver extract, protein, riboflavin, and other factors.
    Cancer research, 1947, Volume: 7, Issue:3

    Topics: Azo Compounds; Carcinogenesis; Cysteine; Cystine; Diet; Liver Extracts; Neoplasms; p-Dimethylaminoazobenzene; Proteins; Riboflavin

1947
Degradation of cystine peptides by tissues; dehydropeptidase activity in normal and neoplastic tissues.
    Journal of the National Cancer Institute, 1946, Volume: 6

    Topics: Cystine; Enzymes; Neoplasms; Peptide Hydrolases; Peptides

1946
[The presence of an organic transsulfurase in normal and in neoplastic tissues].
    Bollettino della Societa italiana di biologia sperimentale, 1953, Volume: 29, Issue:1

    Topics: Biochemical Phenomena; Cysteine; Cystine; Enzymes; Health Services; Neoplasms; Sulfurtransferases; Thiocyanates

1953
[Studies on sulfur metabolism in cancer patients].
    Zeitschrift fur klinische Medizin, 1953, Volume: 152, Issue:3

    Topics: Biochemical Phenomena; Cystine; Humans; Neoplasms; Sulfur

1953
Studies on analogues of L-cysteine and L-cystine. II. The effect of selenium cystine on Murphy lymphosarcoma tumor cells in the rat.
    Blood, 1956, Volume: 11, Issue:1

    Topics: Animals; Cysteine; Cystine; Lymphoma; Lymphoma, Non-Hodgkin; Neoplasms; Neoplasms, Experimental; Rats; Selenium

1956
Cystine-cysteine concentration in homogenate and cell fractions of rat liver during azo dye feeding and regeneration and in rat liver tumor.
    Revue canadienne de biologie, 1955, Volume: 14, Issue:3

    Topics: Animals; Azo Compounds; Cysteine; Cystine; Liver; Neoplasms; Organic Chemicals; Rats; Regeneration

1955
On the activity of cystine desulfurase in mouse tumors.
    The Journal of biological chemistry, 1958, Volume: 233, Issue:4

    Topics: Animals; Cystine; Encephalomyelitis; Hydro-Lyases; Mice; Neoplasms; Oxidoreductases

1958
Studies on the incorporation of 35S labelled cystine into the leucocytes of tumour bearing rats.
    Acta physiologica Scandinavica, 1959, Jun-24, Volume: 46

    Topics: Animals; Cystine; Leukocytes; Neoplasms; Rats

1959
Comparative study of the cystine-cysteine content of the mucoprotein of normal, silicotic and cancerous sera.
    Clinica chimica acta; international journal of clinical chemistry, 1962, Volume: 7

    Topics: Cysteine; Cystine; Hematologic Diseases; Humans; Mucoproteins; Neoplasms; Oxidation-Reduction; Silicosis

1962
[Prevention of leukocytopenia in the chemotherapy of cancer. 1. Comparative study of drugs causing so-called leukocytosis].
    [Chiryo] [Therapy], 1963, Volume: 45

    Topics: Antineoplastic Agents; Chlorophyll; Cystine; Homocysteine; Humans; Leukocyte Disorders; Leukocytosis; Leukopenia; Neoplasms

1963
[Prevention of leukocytopenia in the chemotherapy of cancer. 1. Comparative study of the drugs causing so-called leukocytosis].
    [Chiryo] [Therapy], 1963, Volume: 45

    Topics: Antineoplastic Agents; Chlorophyll; Cystine; Homocysteine; Humans; Leukocyte Disorders; Leukocytosis; Leukopenia; Neoplasms

1963
THE EFFECT OF NITROGEN MUSTARD ON THE LIFE CYCLE OF EHRLICH ASCITES TUMOR CELLS IN VIVO.
    British journal of cancer, 1964, Volume: 18

    Topics: Animals; Carcinoma; Carcinoma, Ehrlich Tumor; Cystine; DNA; DNA, Neoplasm; Leucine; Mechlorethamine; Mice; Neoplasms; Neoplasms, Experimental; Nitrogen Mustard Compounds; Peritoneal Neoplasms; Pharmacology; Research; Thymidine; Tissue Culture Techniques

1964
AUTORADIOGRAPHIC ANALYSIS OF UPTAKE OF TRITIATED THYMIDINE AND S35 CYSTINE BY CULTURED HUMAN CERVICAL EXPLANTS UNDERGOING METAPLASIA.
    Journal of the National Cancer Institute, 1964, Volume: 32

    Topics: Autoradiography; Carcinoma; Carcinoma, Squamous Cell; Cervix Uteri; Cystine; Female; Humans; Metaplasia; Neoplasms; Sulfur Isotopes; Thymidine; Tissue Culture Techniques; Tritium; Uterine Cervical Neoplasms

1964
POLAROGRAPHIC REACTIONS OF PLASMA PROTEINS AND THEIR CLINICAL SIGNIFICANCE.
    Clinical chemistry, 1965, Volume: 11

    Topics: Alcohols; Animals; Arthritis; Benz(a)Anthracenes; Blood Proteins; Clinical Laboratory Techniques; Cobalt; Cysteine; Cystine; Dogs; Ethanol; Haplorhini; Laboratories; Neoplasms; Polarography; Research; Toxicology

1965
Cystine-glutamate transporter SLC7A11 in cancer chemosensitivity and chemoresistance.
    Cancer research, 2005, Aug-15, Volume: 65, Issue:16

    Topics: Amino Acid Transport System y+; Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Cell Line, Tumor; Cystine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Glutathione; Humans; Neoplasms; RNA, Small Interfering

2005
Dietary Factors in the Utilization of Homocystine.
    Proceedings of the National Academy of Sciences of the United States of America, 1948, Volume: 34, Issue:3

    Topics: Cysteine; Cystine; Diet; Ear Neoplasms; Homocystine; Humans; Neoplasms

1948
[Does cystine accumulate in malignancies].
    Munchener medizinische Wochenschrift (1950), 1966, Dec-02, Volume: 108, Issue:48

    Topics: Animals; Autoradiography; Carcinoma, Ehrlich Tumor; Cystine; Humans; Kidney; Liver; Mice; Neoplasms; Neoplasms, Experimental; Rats; Sarcoma, Experimental; Spleen; Sulfur Isotopes

1966
Antioxidant-related parameters in patients treated for cancer chemoprevention with N-acetylcysteine.
    European journal of cancer (Oxford, England : 1990), 1995, Volume: 31A, Issue:6

    Topics: Aged; Aged, 80 and over; Cystine; Erythrocytes; Female; Glutathione; Humans; Male; Middle Aged; Mouth Mucosa; Neoplasms; Reactive Oxygen Species

1995
Cystine levels, cystine flux, and protein catabolism in cancer cachexia, HIV/SIV infection, and senescence.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1997, Volume: 11, Issue:1

    Topics: Adipose Tissue; Adolescent; Adult; Aging; Animals; Cachexia; CD4 Lymphocyte Count; Citrulline; Cystine; Female; Glutamine; HIV Infections; Humans; Macaca; Male; Middle Aged; Muscle Proteins; Muscle, Skeletal; Neoplasms; Simian Acquired Immunodeficiency Syndrome; Taurine

1997
The metabolism of sulphur in relation to the biochemistry of cystine and cysteine: its fundamental importance in biology. A cyclic interchange between their mono- and di-sulphides is the unique reaction creating life and intelligence.
    Medical hypotheses, 2001, Volume: 56, Issue:5

    Topics: Cysteine; Cystine; Humans; Neoplasms; Sulfides; Sulfur

2001