Compounds > cystine

cystine and Lung Neoplasms

cystine has been researched along with Lung Neoplasms in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.35)18.7374
1990's6 (26.09)18.2507
2000's3 (13.04)29.6817
2010's6 (26.09)24.3611
2020's7 (30.43)2.80

Authors

AuthorsStudies
Chen, X; Du, H; He, X; Li, P; Pan, Y; Ren, K; Wang, T; Xie, W; Yang, H; Yang, M; Yu, A; Zhang, W; Zhao, Y; Zheng, H; Zhou, Z1
Jiang, L; Lin, J; Qiu, L; Ren, J; Tan, X; Zhang, G; Zhu, S1
Chen, J; Chen, X; Du, W; Feng, Y; Li, M; Liu, P; Liu, R; Shi, M; Xu, J; Zhao, L; Zhao, Y1
Bai, HJ; Boufraqech, M; DeVore, JE; Durant, ST; Jones, MD; Li, H; Liu, Y; Maier, EY; Wang, S; Weyemi, U; Wilson, CN; Xiao, Y1
Chaudhari, P; Epari, S; Gandhi, KA; Gandhi, VV; Goda, JS; Gota, V; Jain, VK; Joshi, K; Kembhavi, S; Kunwar, A; Mohanty, B; Priyadarsini, KI; Rane, S; Sadanpurwala, A1
Duan, J; Feng, Y; Liu, P; Wu, D; Xiao, H; Zhao, L; Zhou, Y1
Deng, J; Guo, W; Hu, M; Jing, B; Kuang, Y; Li, K; Li, Q; Liao, Y; Lin, SH; Ling, J; Liu, S; Song, H; Sun, B; Tong, L; Wang, Q; Wang, T; Wu, Y; Xu, D; Yao, F; Yin, H; Zhou, BP1
Aa, JY; Cao, B; Guo, SH; Li, SJ; Lu, ZY; Sun, RB; Wang, GJ; Xie, Y1
Eisenberg, R; Harris, BK; Heidi, C; Hoeksema, MD; Ji, X; Massion, PP; Qian, J; Rahman, SMJ; Rathmell, JC; Siska, PJ; Trenary, IA; Young, JD; Zou, Y1
Chen, T; Fan, C; Fu, X; Li, X; Wong, YS; Zheng, W1
Arnér, ES; Cebula, M; Holmgren, A; Johansson, K; Lundberg, JO; Pader, I; Sengupta, R; Xu, J1
Accart, N; Arigoni, M; Aurisicchio, L; Barrera, G; Bolli, E; Calogero, RA; Cavallo, F; Conti, L; Lanzardo, S; Macagno, M; Pizzimenti, S; Rooke, R; Ruiu, R1
Cramer, SL; Crighton, T; Labuschagne, C; Lamb, RF; Mason, D; Pardo, OE; Poursaitidis, I; Rowlinson, SW; Roy, R; Seckl, MJ; Stone, E; Triplett, K; Wang, X1
Buckley, AR; Dockery, P; Gout, PW; Guan, J; Karp, CM; Lam, S; Lo, M; Mahon, S; Wang, YZ1
Björnstedt, M; Danielsson, O; Fernandes, AP; Hebert, C; Larsen, EH; Olm, E; Rundlöf, AK1
Cho, WK; Choi, S; Hwang, KS; Im, DS; Jung, CR; Kwon, ST; Yoo, J1
Kang, YJ1
Breton, C; Meyn, RE; Story, MD1
Houghton, PJ; Jackson, S; Li, G; Twentyman, PR; Zhang, L1
Daniel, V; Drings, P; Eck, HP; Fätkenheuer, G; Mertens, T; Näher, H; Petzoldt, D; Pohl, C; Rosokat, H; Schrappe, M1
Brodie, AE; Reed, DJ2
Clapper, JA; Enger, MD; Jenkins, P; Kang, YJ; Nuutero, ST1

Other Studies

23 other study(ies) available for cystine and Lung Neoplasms

ArticleYear
Quantitative proteomic analysis of the effects of dietary deprivation of methionine and cystine on A549 xenograft and A549 xenograft-bearing mouse.
    Proteomics, 2021, Volume: 21, Issue:20

    Topics: Animals; Cystine; Epithelial-Mesenchymal Transition; Heterografts; Lung Neoplasms; Methionine; Mice; Proteomics

2021
    Molecular pharmaceutics, 2022, 07-04, Volume: 19, Issue:7

    Topics: Animals; Antigens, Neoplasm; Cell Line, Tumor; Cystine; Gallium Radioisotopes; Integrin alphaVbeta3; Integrins; Lung Neoplasms; Mice; Mice, Nude; Peptides; Positron-Emission Tomography; Tissue Distribution

2022
COX7A1 enhances the sensitivity of human NSCLC cells to cystine deprivation-induced ferroptosis via regulating mitochondrial metabolism.
    Cell death & disease, 2022, 11-23, Volume: 13, Issue:11

    Topics: Carcinoma, Non-Small-Cell Lung; Cysteine; Cystine; Electron Transport Complex IV; Ferroptosis; Humans; Lung Neoplasms; Mitochondria

2022
CRISPR metabolic screen identifies ATM and KEAP1 as targetable genetic vulnerabilities in solid tumors.
    Proceedings of the National Academy of Sciences of the United States of America, 2023, 02-07, Volume: 120, Issue:6

    Topics: Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Cystine; Humans; Kelch-Like ECH-Associated Protein 1; Lung Neoplasms; NF-E2-Related Factor 2

2023
Oral administration of 3,3'-diselenodipropionic acid prevents thoracic radiation induced pneumonitis in mice by suppressing NF-kB/IL-17/G-CSF/neutrophil axis.
    Free radical biology & medicine, 2019, Volume: 145

    Topics: A549 Cells; Administration, Oral; Animals; Cystine; Disease Models, Animal; Granulocyte Colony-Stimulating Factor; Humans; Interleukin-17; Lung; Lung Neoplasms; Mice; Neutrophils; NF-kappa B; Organoselenium Compounds; Pneumonia; Propionates; Radiation Injuries; Selenium Compounds; Signal Transduction

2019
NRF2 regulates the sensitivity of human NSCLC cells to cystine deprivation-induced ferroptosis via FOCAD-FAK signaling pathway.
    Redox biology, 2020, Volume: 37

    Topics: Carcinoma, Non-Small-Cell Lung; Cystine; Ferroptosis; Focal Adhesion Protein-Tyrosine Kinases; Humans; Lung Neoplasms; NF-E2-Related Factor 2; Signal Transduction; Tumor Suppressor Proteins

2020
Dysregulated Glutamate Transporter SLC1A1 Propels Cystine Uptake via Xc
    Cancer research, 2021, 02-01, Volume: 81, Issue:3

    Topics: Animals; Antiporters; Cell Death; Cell Line, Tumor; Cystine; Excitatory Amino Acid Transporter 3; Glutamic Acid; Glutamine; Glutathione; Lung Neoplasms; Mice; Mice, Nude; Oxidative Stress; Receptors, G-Protein-Coupled; Stress, Physiological; Up-Regulation

2021
Cystine supplementation rebalances the redox homeostasis of microenvironment in non-small cell lung cancer cells and reverses their resistance to docetaxel.
    Acta pharmacologica Sinica, 2021, Volume: 42, Issue:12

    Topics: A549 Cells; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Non-Small-Cell Lung; Cystine; Docetaxel; Drug Resistance, Neoplasm; Drug Synergism; Glutathione; Homeostasis; Humans; Lung Neoplasms; Male; Mice, Nude; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Tumor Microenvironment; Up-Regulation

2021
xCT (SLC7A11)-mediated metabolic reprogramming promotes non-small cell lung cancer progression.
    Oncogene, 2018, Volume: 37, Issue:36

    Topics: 3T3 Cells; A549 Cells; Amino Acid Transport System y+; Animals; Carcinoma, Non-Small-Cell Lung; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cystine; Cytoplasm; Disease Progression; Female; Glutamine; Humans; Lung Neoplasms; Male; Mice; Middle Aged

2018
Enhancement of auranofin-induced lung cancer cell apoptosis by selenocystine, a natural inhibitor of TrxR1 in vitro and in vivo.
    Cell death & disease, 2014, Apr-24, Volume: 5

    Topics: Animals; Apoptosis; Auranofin; Cell Line, Tumor; Cell Proliferation; Cystine; DNA Damage; Drug Synergism; Extracellular Signal-Regulated MAP Kinases; Humans; Lung Neoplasms; Mice; Mitochondria; Mitogen-Activated Protein Kinase Kinases; Models, Biological; Organoselenium Compounds; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Signal Transduction; Thioredoxin Reductase 1; Xenograft Model Antitumor Assays

2014
Thioredoxin-related protein of 14 kDa is an efficient L-cystine reductase and S-denitrosylase.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, May-13, Volume: 111, Issue:19

    Topics: Carcinoma, Squamous Cell; Cysteine; Cystine; Enzyme Activation; Glutathione; HEK293 Cells; HT29 Cells; Humans; Hydrogen Peroxide; Lung Neoplasms; NADH, NADPH Oxidoreductases; NADP; Nitric Oxide; Oxidants; Oxidation-Reduction; Oxidative Stress; Substrate Specificity; Sulfur; Thioredoxin Reductase 1; Thioredoxins

2014
Immunotargeting of Antigen xCT Attenuates Stem-like Cell Behavior and Metastatic Progression in Breast Cancer.
    Cancer research, 2016, Jan-01, Volume: 76, Issue:1

    Topics: Amino Acid Transport Systems; Animals; Antigens, Neoplasm; Breast Neoplasms; Cancer Vaccines; Cell Line, Tumor; Cystine; Disease Progression; Female; Glutamic Acid; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Knockout; Neoplastic Stem Cells; NIH 3T3 Cells; Up-Regulation; Vaccines, DNA; Xenograft Model Antitumor Assays

2016
Oncogene-Selective Sensitivity to Synchronous Cell Death following Modulation of the Amino Acid Nutrient Cystine.
    Cell reports, 2017, 03-14, Volume: 18, Issue:11

    Topics: Amino Acids; Animals; Breast; Carcinoma, Non-Small-Cell Lung; Cell Death; Cell Line, Tumor; Cell Survival; Cysteine; Cystine; Down-Regulation; Epithelial Cells; ErbB Receptors; Female; Glutathione; Glutathione Peroxidase; Hydrogen Peroxide; Iron; Lung Neoplasms; MAP Kinase Signaling System; Mice, SCID; Mutation; Oncogenes; Phospholipid Hydroperoxide Glutathione Peroxidase

2017
The xc- cystine/glutamate antiporter as a potential therapeutic target for small-cell lung cancer: use of sulfasalazine.
    Cancer chemotherapy and pharmacology, 2009, Volume: 64, Issue:3

    Topics: Amino Acid Transport System y+; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Carcinoma, Small Cell; Cell Line, Tumor; Cystine; Drug Delivery Systems; Gene Expression Regulation, Neoplastic; Glutathione; Humans; Inhibitory Concentration 50; Lung Neoplasms; Male; Mice; Mice, Inbred NOD; Mice, SCID; Sodium Glutamate; Sulfasalazine; Xenograft Model Antitumor Assays

2009
Extracellular thiol-assisted selenium uptake dependent on the x(c)- cystine transporter explains the cancer-specific cytotoxicity of selenite.
    Proceedings of the National Academy of Sciences of the United States of America, 2009, Jul-07, Volume: 106, Issue:27

    Topics: Amino Acid Transport System y+; Antiporters; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Death; Cell Line, Tumor; Cystine; Drug Resistance, Neoplasm; Extracellular Space; Glutathione; Humans; Lung Neoplasms; Models, Biological; Organoselenium Compounds; Oxidation-Reduction; Selenium; Sodium Selenite; Sulfhydryl Compounds

2009
Adeno-associated virus-mediated gene transfer of a secreted form of TRAIL inhibits tumor growth and occurrence in an experimental tumor model.
    The journal of gene medicine, 2006, Volume: 8, Issue:2

    Topics: Animals; Apoptosis Regulatory Proteins; Cell Line, Tumor; Cystine; Dependovirus; Female; Genetic Therapy; Genetic Vectors; Hepatocytes; Humans; Lung Neoplasms; Membrane Glycoproteins; Mice; Mice, Nude; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha

2006
Exogenous glutathione attenuates the antiproliferative effect of buthionine sulfoximine.
    Toxicology, 1994, Mar-11, Volume: 88, Issue:1-3

    Topics: Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Carcinoma; Cell Division; Cystine; Glutathione; Humans; Lung Neoplasms; Methionine Sulfoximine; Tumor Cells, Cultured

1994
Bcl-2 expression correlates with apoptosis induction but not loss of clonogenic survival in small cell lung cancer cell lines treated with etoposide.
    Anti-cancer drugs, 1998, Volume: 9, Issue:9

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Small Cell; Cell Survival; Culture Media; Cystine; Etoposide; Gene Expression; Genes, bcl-2; Humans; Lung Neoplasms; Methionine; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured

1998
[Alkaloids in Sophora alopecuroides seed and relevant tests for activity].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1997, Volume: 22, Issue:12

    Topics: Alkaloids; Anti-Bacterial Agents; Anti-Infective Agents; Antineoplastic Agents, Phytogenic; Cystine; Drugs, Chinese Herbal; Fabaceae; Lung Neoplasms; Matrines; Nicotine; Plants, Medicinal; Quinolizines; Seeds; Tumor Cells, Cultured

1997
T4+ cell numbers are correlated with plasma glutamate and cystine levels: association of hyperglutamataemia with immunodeficiency in diseases with different aetiologies.
    International immunology, 1992, Volume: 4, Issue:1

    Topics: CD4-Positive T-Lymphocytes; Cystine; Glutamates; Glutamic Acid; HIV Seropositivity; HIV-1; Humans; Immunologic Deficiency Syndromes; Lactates; Lactic Acid; Leukocyte Count; Lung Neoplasms; Pyruvates; Pyruvic Acid

1992
Cellular recovery of glyceraldehyde-3-phosphate dehydrogenase activity and thiol status after exposure to hydroperoxides.
    Archives of biochemistry and biophysics, 1990, Volume: 276, Issue:1

    Topics: Cell Line; Cysteamine; Cysteine; Cystine; Dithiothreitol; Ethacrynic Acid; Ethylmaleimide; Glutathione; Glutathione Disulfide; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Hydrogen Peroxide; Kinetics; Lung Neoplasms; Oxidation-Reduction; Peroxides; Sulfhydryl Compounds; tert-Butylhydroperoxide; Ultrasonics

1990
Cellular cadmium responses in subpopulations T20 and T27 of human lung carcinoma A549 cells.
    Toxicology, 1990, Apr-17, Volume: 61, Issue:2

    Topics: Cadmium; Cystine; Glutathione; Humans; Lung Neoplasms; Metallothionein; Tumor Cells, Cultured; Tumor Stem Cell Assay

1990
Buthionine sulfoximine inhibition of cystine uptake and glutathione biosynthesis in human lung carcinoma cells.
    Toxicology and applied pharmacology, 1985, Mar-15, Volume: 77, Issue:3

    Topics: Buthionine Sulfoximine; Cell Line; Cysteine; Cystine; Glutathione; Humans; Lung Neoplasms; Methionine Sulfoximine; Sulfur Radioisotopes

1985