cystine has been researched along with Glioma in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (29.41) | 18.2507 |
| 2000's | 2 (11.76) | 29.6817 |
| 2010's | 7 (41.18) | 24.3611 |
| 2020's | 3 (17.65) | 2.80 |
| Authors | Studies |
|---|---|
| Camphausen, K; Dios-Esponera, A; Dowdy, T; Gilbert, MR; Herold-Mende, CC; Jung, J; Kramp, T; Larion, M; Lita, A; Ruiz-Rodado, V; Zhang, L; Zhang, M | 1 |
| Dahlmanns, JK; Dahlmanns, M; Savaskan, N; Steiner, HH; Yakubov, E | 1 |
| Bowles, C; Chase, LA; Engelsman, SB; Flores, G; King, AG; Robinson, AE; Rothstein, J; Schiller, N; Smith, SL; VerHeulen Kleyn, M | 1 |
| Holt, KT; Ogunrinu-Babarinde, T; Robert, SM; Sontheimer, H | 1 |
| Ai, J; Bi, Y; Hou, X; Li, C; Liu, H; Liu, Y; Peng, F; Shen, C; Wang, C; Wang, K; Wang, X; Yin, F; Zhang, D; Zhang, J; Zhang, W; Zhao, B; Zhao, S; Zhong, C | 1 |
| Hansen, H; Hashizume, Y; Loiacono, KA; Rojas, C; Sahni, V; Sattler, R; Slusher, BS; Tendyke, K; Thomas, AG | 1 |
| Abe, S; Akashi, K; Akiyama, T; Baba, E; Furnari, FB; Ishikawa, M; Iwasaki, Y; Masuko, T; Morikawa, T; Nagane, M; Nagano, O; Ohmura, M; Okazaki, S; Onishi, N; Sampetrean, O; Saya, H; Seishima, R; Shimizu, M; Suematsu, M; Takao, A; Tsuchihashi, K; Wakimoto, H; Yoshikawa, M | 1 |
| Alvarado, O; Blower, PE; Gout, PW; Huang, Y; Pham, AN; Ravula, R | 1 |
| Eyüpoglu, IY; Hahnen, E; Hauke, J; Savaskan, NE; Seufert, S; Tränkle, C | 1 |
| Bannai, S; Beck, H; Conrad, M; De Bundel, D; Fernando, R; Kim, SW; Kobayashi, S; Massie, A; Michotte, Y; Plesnila, N; Sato, H; Schallier, A; Smolders, I; Vermoesen, K | 1 |
| Albrecht, J; Dybel, A; Hilgier, W; Oja, SS; Saransaari, P; Wegrzynowicz, M | 1 |
| Sontheimer, H | 1 |
| Shinagawa, S | 1 |
| Kato, S; Mawatari, K; Sugitani, K; Takadera, T; Yasui, Y | 1 |
| Rothstein, JD; Sontheimer, H; Ye, ZC | 1 |
| Kato, S; Kuo, CH; Mawatari, K; Negishi, K | 1 |
| Bannai, S; Cho, Y | 1 |
2 review(s) available for cystine and Glioma
| Article | Year |
|---|---|
Glial Glutamate Transporter-Mediated Plasticity: System x
Topics: Alzheimer Disease; Amino Acid Transport System X-AG; Amino Acid Transport System y+; Amyotrophic Lateral Sclerosis; Antioxidants; Cystine; Glioma; Glutamic Acid; Humans; Microglia; Multiple Sclerosis; Parkinson Disease | 2023 |
A role for glutamate in growth and invasion of primary brain tumors.
Topics: Amino Acid Transport System X-AG; Animals; Antineoplastic Agents; Brain Neoplasms; Cystine; Glioma; Glutamic Acid; Humans; Neoplasm Invasiveness | 2008 |
15 other study(ies) available for cystine and Glioma
| Article | Year |
|---|---|
Cysteine is a limiting factor for glioma proliferation and survival.
Topics: Animals; Cell Proliferation; Cysteine; Cystine; Glioma; Glutathione; Humans; Mice; Tumor Microenvironment | 2022 |
Hydrogen peroxide triggers an increase in cell surface expression of system x
Topics: Amino Acid Transport System y+; Cell Membrane; Cystine; Glioma; Glutamic Acid; Glutathione; Humans; Hydrogen Peroxide; Oxidative Stress | 2020 |
Role of glutamate transporters in redox homeostasis of the brain.
Topics: Amino Acid Transport System X-AG; Animals; Brain; Brain Chemistry; Cystine; Glioma; Glutathione; Homeostasis; Humans; Mice; Nervous System Diseases; Oxidation-Reduction; Xenograft Model Antitumor Assays | 2014 |
Methionine and cystine double deprivation stress suppresses glioma proliferation via inducing ROS/autophagy.
Topics: Animals; Autophagy; Brain Neoplasms; Cell Proliferation; Cystine; Glioma; Methionine; Mice; Mice, Inbred BALB C; Mice, Nude; Reactive Oxygen Species | 2015 |
High-Throughput Assay Development for Cystine-Glutamate Antiporter (xc-) Highlights Faster Cystine Uptake than Glutamate Release in Glioma Cells.
Topics: Amino Acid Transport System y+; Benzoates; Brain Neoplasms; Cell Line, Tumor; Cystine; Databases, Chemical; Gene Expression Regulation, Neoplastic; Glioma; Glutamic Acid; Glycine; High-Throughput Screening Assays; Humans; Inhibitory Concentration 50; Models, Biological; RNA, Messenger; Sulfasalazine; Time Factors | 2015 |
The EGF Receptor Promotes the Malignant Potential of Glioma by Regulating Amino Acid Transport System xc(-).
Topics: Amino Acid Transport System y+; Animals; Antioxidants; Apoptosis; Brain Neoplasms; Cell Membrane; Cell Movement; Cell Proliferation; Cystine; ErbB Receptors; Gene Expression Regulation, Neoplastic; Glioma; Glutamic Acid; Humans; Mice; Mice, Inbred NOD; Mice, Nude; Mice, SCID; Reactive Oxygen Species; Sulfasalazine; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2016 |
Pharmacogenomic approach reveals a role for the x(c)- cystine/glutamate antiporter in growth and celastrol resistance of glioma cell lines.
Topics: Amino Acid Transport System y+; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cystine; Drug Resistance, Neoplasm; Gene Expression Profiling; Glioma; Humans; Oligonucleotide Array Sequence Analysis; Pentacyclic Triterpenes; Pharmacogenetics; RNA, Small Interfering; Sulfasalazine; Triterpenes | 2010 |
Dissection of mitogenic and neurodegenerative actions of cystine and glutamate in malignant gliomas.
Topics: Animals; Brain Neoplasms; Cell Growth Processes; Cell Line, Tumor; Cystine; Down-Regulation; Glioma; Glutamic Acid; Humans; Mice; Rats; Receptors, AMPA; Signal Transduction; Transfection | 2011 |
Dopaminergic neurons of system x(c)⁻-deficient mice are highly protected against 6-hydroxydopamine-induced toxicity.
Topics: Aging; Amino Acid Transport System y+; Animals; Corpus Striatum; Cystine; Dopamine; Glioma; Glutamic Acid; Glutathione; Mice; Mice, Knockout; Neurodegenerative Diseases; Neurons; Oxidopamine; Substantia Nigra; Tumor Cells, Cultured | 2011 |
Upregulation of cerebral cortical glutathione synthesis by ammonia in vivo and in cultured glial cells: the role of cystine uptake.
Topics: Ammonia; Animals; Animals, Newborn; Biological Transport; Bucladesine; Cell Differentiation; Cell Line, Tumor; Cells, Cultured; Cerebral Cortex; Corpus Striatum; Cystine; Glioma; Glutathione; Male; Microdialysis; Neuroglia; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Rats, Wistar | 2007 |
Serotonin protects C6 glioma cells from glutamate toxicity.
Topics: Animals; Antiporters; Cell Death; Cells, Cultured; Cerebellar Cortex; Cerebral Cortex; Cystine; Excitatory Amino Acid Antagonists; Glioma; Gliotoxin; Glutamates; Glutamic Acid; Glutathione; Lipid Peroxidation; Nerve Tissue Proteins; Neuroglia; Neurons; Neurotransmitter Agents; Quisqualic Acid; Rats; Serotonin; Tumor Cells, Cultured | 1994 |
Reactive oxygen species involved in the glutamate toxicity of C6 glioma cells via xc antiporter system.
Topics: Adenosine Triphosphate; Animals; Antiporters; Brain Neoplasms; Cell Death; Cell Nucleus; Cystine; DNA Damage; Free Radical Scavengers; Glioma; Glutamate-Ammonia Ligase; Glutamic Acid; Glutathione; Glyceraldehyde-3-Phosphate Dehydrogenases; Lipid Peroxides; Rats; Reactive Oxygen Species; Tumor Cells, Cultured | 1996 |
Compromised glutamate transport in human glioma cells: reduction-mislocalization of sodium-dependent glutamate transporters and enhanced activity of cystine-glutamate exchange.
Topics: Amino Acid Substitution; Amino Acid Transport System X-AG; Animals; Astrocytes; ATP-Binding Cassette Transporters; Benzoates; Brain Neoplasms; Cells, Cultured; Cystine; Excitatory Amino Acid Antagonists; Glioma; Glucose Transporter Type 1; Glutamic Acid; Glycine; Humans; Monosaccharide Transport Proteins; Rats; Rats, Sprague-Dawley; Sodium; Tissue Distribution | 1999 |
A mechanism for glutamate toxicity in the C6 glioma cells involving inhibition of cystine uptake leading to glutathione depletion.
Topics: Animals; Biological Transport; Cell Line; Cystine; DNA, Neoplasm; Dose-Response Relationship, Drug; Glioma; Glutamates; Glutamic Acid; Glutathione; Kinetics; Neurotoxins; Rats; Sulfur Radioisotopes; Tritium | 1992 |
Uptake of glutamate and cysteine in C-6 glioma cells and in cultured astrocytes.
Topics: Amino Acids; Animals; Astrocytes; Biological Transport; Cells, Cultured; Cystine; Excitatory Amino Acid Antagonists; Glioma; Glutamates; Glutamic Acid; Glutathione; Kinetics; Sodium; Tumor Cells, Cultured | 1990 |