cystine and Glioma

cystine has been researched along with Glioma in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (29.41)18.2507
2000's2 (11.76)29.6817
2010's7 (41.18)24.3611
2020's3 (17.65)2.80

Authors

AuthorsStudies
Camphausen, K; Dios-Esponera, A; Dowdy, T; Gilbert, MR; Herold-Mende, CC; Jung, J; Kramp, T; Larion, M; Lita, A; Ruiz-Rodado, V; Zhang, L; Zhang, M1
Dahlmanns, JK; Dahlmanns, M; Savaskan, N; Steiner, HH; Yakubov, E1
Bowles, C; Chase, LA; Engelsman, SB; Flores, G; King, AG; Robinson, AE; Rothstein, J; Schiller, N; Smith, SL; VerHeulen Kleyn, M1
Holt, KT; Ogunrinu-Babarinde, T; Robert, SM; Sontheimer, H1
Ai, J; Bi, Y; Hou, X; Li, C; Liu, H; Liu, Y; Peng, F; Shen, C; Wang, C; Wang, K; Wang, X; Yin, F; Zhang, D; Zhang, J; Zhang, W; Zhao, B; Zhao, S; Zhong, C1
Hansen, H; Hashizume, Y; Loiacono, KA; Rojas, C; Sahni, V; Sattler, R; Slusher, BS; Tendyke, K; Thomas, AG1
Abe, S; Akashi, K; Akiyama, T; Baba, E; Furnari, FB; Ishikawa, M; Iwasaki, Y; Masuko, T; Morikawa, T; Nagane, M; Nagano, O; Ohmura, M; Okazaki, S; Onishi, N; Sampetrean, O; Saya, H; Seishima, R; Shimizu, M; Suematsu, M; Takao, A; Tsuchihashi, K; Wakimoto, H; Yoshikawa, M1
Alvarado, O; Blower, PE; Gout, PW; Huang, Y; Pham, AN; Ravula, R1
Eyüpoglu, IY; Hahnen, E; Hauke, J; Savaskan, NE; Seufert, S; Tränkle, C1
Bannai, S; Beck, H; Conrad, M; De Bundel, D; Fernando, R; Kim, SW; Kobayashi, S; Massie, A; Michotte, Y; Plesnila, N; Sato, H; Schallier, A; Smolders, I; Vermoesen, K1
Albrecht, J; Dybel, A; Hilgier, W; Oja, SS; Saransaari, P; Wegrzynowicz, M1
Sontheimer, H1
Shinagawa, S1
Kato, S; Mawatari, K; Sugitani, K; Takadera, T; Yasui, Y1
Rothstein, JD; Sontheimer, H; Ye, ZC1
Kato, S; Kuo, CH; Mawatari, K; Negishi, K1
Bannai, S; Cho, Y1

Reviews

2 review(s) available for cystine and Glioma

ArticleYear
Glial Glutamate Transporter-Mediated Plasticity: System x
    Frontiers in bioscience (Landmark edition), 2023, 03-20, Volume: 28, Issue:3

    Topics: Alzheimer Disease; Amino Acid Transport System X-AG; Amino Acid Transport System y+; Amyotrophic Lateral Sclerosis; Antioxidants; Cystine; Glioma; Glutamic Acid; Humans; Microglia; Multiple Sclerosis; Parkinson Disease

2023
A role for glutamate in growth and invasion of primary brain tumors.
    Journal of neurochemistry, 2008, Volume: 105, Issue:2

    Topics: Amino Acid Transport System X-AG; Animals; Antineoplastic Agents; Brain Neoplasms; Cystine; Glioma; Glutamic Acid; Humans; Neoplasm Invasiveness

2008

Other Studies

15 other study(ies) available for cystine and Glioma

ArticleYear
Cysteine is a limiting factor for glioma proliferation and survival.
    Molecular oncology, 2022, Volume: 16, Issue:9

    Topics: Animals; Cell Proliferation; Cysteine; Cystine; Glioma; Glutathione; Humans; Mice; Tumor Microenvironment

2022
Hydrogen peroxide triggers an increase in cell surface expression of system x
    Neurochemistry international, 2020, Volume: 134

    Topics: Amino Acid Transport System y+; Cell Membrane; Cystine; Glioma; Glutamic Acid; Glutathione; Humans; Hydrogen Peroxide; Oxidative Stress

2020
Role of glutamate transporters in redox homeostasis of the brain.
    Neurochemistry international, 2014, Volume: 73

    Topics: Amino Acid Transport System X-AG; Animals; Brain; Brain Chemistry; Cystine; Glioma; Glutathione; Homeostasis; Humans; Mice; Nervous System Diseases; Oxidation-Reduction; Xenograft Model Antitumor Assays

2014
Methionine and cystine double deprivation stress suppresses glioma proliferation via inducing ROS/autophagy.
    Toxicology letters, 2015, Jan-22, Volume: 232, Issue:2

    Topics: Animals; Autophagy; Brain Neoplasms; Cell Proliferation; Cystine; Glioma; Methionine; Mice; Mice, Inbred BALB C; Mice, Nude; Reactive Oxygen Species

2015
High-Throughput Assay Development for Cystine-Glutamate Antiporter (xc-) Highlights Faster Cystine Uptake than Glutamate Release in Glioma Cells.
    PloS one, 2015, Volume: 10, Issue:8

    Topics: Amino Acid Transport System y+; Benzoates; Brain Neoplasms; Cell Line, Tumor; Cystine; Databases, Chemical; Gene Expression Regulation, Neoplastic; Glioma; Glutamic Acid; Glycine; High-Throughput Screening Assays; Humans; Inhibitory Concentration 50; Models, Biological; RNA, Messenger; Sulfasalazine; Time Factors

2015
The EGF Receptor Promotes the Malignant Potential of Glioma by Regulating Amino Acid Transport System xc(-).
    Cancer research, 2016, 05-15, Volume: 76, Issue:10

    Topics: Amino Acid Transport System y+; Animals; Antioxidants; Apoptosis; Brain Neoplasms; Cell Membrane; Cell Movement; Cell Proliferation; Cystine; ErbB Receptors; Gene Expression Regulation, Neoplastic; Glioma; Glutamic Acid; Humans; Mice; Mice, Inbred NOD; Mice, Nude; Mice, SCID; Reactive Oxygen Species; Sulfasalazine; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2016
Pharmacogenomic approach reveals a role for the x(c)- cystine/glutamate antiporter in growth and celastrol resistance of glioma cell lines.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 332, Issue:3

    Topics: Amino Acid Transport System y+; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cystine; Drug Resistance, Neoplasm; Gene Expression Profiling; Glioma; Humans; Oligonucleotide Array Sequence Analysis; Pentacyclic Triterpenes; Pharmacogenetics; RNA, Small Interfering; Sulfasalazine; Triterpenes

2010
Dissection of mitogenic and neurodegenerative actions of cystine and glutamate in malignant gliomas.
    Oncogene, 2011, Jan-06, Volume: 30, Issue:1

    Topics: Animals; Brain Neoplasms; Cell Growth Processes; Cell Line, Tumor; Cystine; Down-Regulation; Glioma; Glutamic Acid; Humans; Mice; Rats; Receptors, AMPA; Signal Transduction; Transfection

2011
Dopaminergic neurons of system x(c)⁻-deficient mice are highly protected against 6-hydroxydopamine-induced toxicity.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2011, Volume: 25, Issue:4

    Topics: Aging; Amino Acid Transport System y+; Animals; Corpus Striatum; Cystine; Dopamine; Glioma; Glutamic Acid; Glutathione; Mice; Mice, Knockout; Neurodegenerative Diseases; Neurons; Oxidopamine; Substantia Nigra; Tumor Cells, Cultured

2011
Upregulation of cerebral cortical glutathione synthesis by ammonia in vivo and in cultured glial cells: the role of cystine uptake.
    Neurochemistry international, 2007, Volume: 50, Issue:7-8

    Topics: Ammonia; Animals; Animals, Newborn; Biological Transport; Bucladesine; Cell Differentiation; Cell Line, Tumor; Cells, Cultured; Cerebral Cortex; Corpus Striatum; Cystine; Glioma; Glutathione; Male; Microdialysis; Neuroglia; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Rats, Wistar

2007
Serotonin protects C6 glioma cells from glutamate toxicity.
    Neuroscience, 1994, Volume: 59, Issue:4

    Topics: Animals; Antiporters; Cell Death; Cells, Cultured; Cerebellar Cortex; Cerebral Cortex; Cystine; Excitatory Amino Acid Antagonists; Glioma; Gliotoxin; Glutamates; Glutamic Acid; Glutathione; Lipid Peroxidation; Nerve Tissue Proteins; Neuroglia; Neurons; Neurotransmitter Agents; Quisqualic Acid; Rats; Serotonin; Tumor Cells, Cultured

1994
Reactive oxygen species involved in the glutamate toxicity of C6 glioma cells via xc antiporter system.
    Neuroscience, 1996, Volume: 73, Issue:1

    Topics: Adenosine Triphosphate; Animals; Antiporters; Brain Neoplasms; Cell Death; Cell Nucleus; Cystine; DNA Damage; Free Radical Scavengers; Glioma; Glutamate-Ammonia Ligase; Glutamic Acid; Glutathione; Glyceraldehyde-3-Phosphate Dehydrogenases; Lipid Peroxides; Rats; Reactive Oxygen Species; Tumor Cells, Cultured

1996
Compromised glutamate transport in human glioma cells: reduction-mislocalization of sodium-dependent glutamate transporters and enhanced activity of cystine-glutamate exchange.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Dec-15, Volume: 19, Issue:24

    Topics: Amino Acid Substitution; Amino Acid Transport System X-AG; Animals; Astrocytes; ATP-Binding Cassette Transporters; Benzoates; Brain Neoplasms; Cells, Cultured; Cystine; Excitatory Amino Acid Antagonists; Glioma; Glucose Transporter Type 1; Glutamic Acid; Glycine; Humans; Monosaccharide Transport Proteins; Rats; Rats, Sprague-Dawley; Sodium; Tissue Distribution

1999
A mechanism for glutamate toxicity in the C6 glioma cells involving inhibition of cystine uptake leading to glutathione depletion.
    Neuroscience, 1992, Volume: 48, Issue:4

    Topics: Animals; Biological Transport; Cell Line; Cystine; DNA, Neoplasm; Dose-Response Relationship, Drug; Glioma; Glutamates; Glutamic Acid; Glutathione; Kinetics; Neurotoxins; Rats; Sulfur Radioisotopes; Tritium

1992
Uptake of glutamate and cysteine in C-6 glioma cells and in cultured astrocytes.
    Journal of neurochemistry, 1990, Volume: 55, Issue:6

    Topics: Amino Acids; Animals; Astrocytes; Biological Transport; Cells, Cultured; Cystine; Excitatory Amino Acid Antagonists; Glioma; Glutamates; Glutamic Acid; Glutathione; Kinetics; Sodium; Tumor Cells, Cultured

1990