cystine and Disease Models, Animal

cystine has been researched along with Disease Models, Animal in 67 studies

Research

Studies (67)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (7.46)	18.7374
1990's	3 (4.48)	18.2507
2000's	14 (20.90)	29.6817
2010's	34 (50.75)	24.3611
2020's	11 (16.42)	2.80

Authors

Authors	Studies
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV	1
Baatsen, P; Baelde, HJ; Berlingerio, SP; Cairoli, S; De Groef, L; de Witte, P; Goffredo, B; He, J; Levtchenko, E; Norton, T; Taeter, H; van den Heuvel, L	1
Kurihara, S; Nishikawa, S; Yoneda, J	1
Bandaranayake, A; Brusniak, MY; Clarke, M; Correnti, CE; Crook, ZR; Friend, DJ; Gewe, MM; Girard, EJ; Lin, I; Mhyre, AJ; Nairn, NW; Olson, JM; Pakiam, F; Phi, TD; Ruff, R; Rupert, PB; Sevilla, GP; Strong, RK	1
Hiura, K; Sasaki, H; Sasaki, N; Sasaki, T; Watanabe, M	1
Battafarano, G; Bellomo, F; Cairoli, S; Camassei, FD; D'Oria, V; De Leo, E; Del Fattore, A; Emma, F; Goffredo, BM; Pezzullo, M; Polishchuk, E; Polishchuk, R; Raso, R; Rega, LR; Taranta, A	1
Chaudhari, P; Epari, S; Gandhi, KA; Gandhi, VV; Goda, JS; Gota, V; Jain, VK; Joshi, K; Kembhavi, S; Kunwar, A; Mohanty, B; Priyadarsini, KI; Rane, S; Sadanpurwala, A	1
Bronowicka-Adamska, P; Gawryś-Kopczyńska, M; Hutsch, T; Maksymiuk, K; Wróbel, M	1
Bai, Y; Cao, D; Han, P; Tang, Y; Wang, J; Wang, X; Wang, Z	1
D'Souza, RF; Davidson, AJ; Harrison, PT; Hollywood, JA; Holm, TM; Przepiorski, A; Sreebhavan, S; Wolvetang, EJ	1
Egashira, N; Kawashiri, T; Kobayashi, D; Shimazoe, T; Tsuchiya, T	1
Alford, A; Borofsky, M; Furrow, E; Lulich, J	1
Irie, J; Itoh, H; Kobayashi, N; Okazaki, S; Sampetrean, O; Saya, H	1
Goldfarb, DS; Hu, L; Sahota, A; Tischfield, JA; Ward, MD	1
Fu, X; Hou, Y; Li, D; Sun, J; Wei, Z; Zhao, M	1
Årstad, E; Gendron, T; Glaser, M; Greenwood, HE; Hochhauser, D; Koglin, N; Lythgoe, MF; Maddocks, ODK; McCormick, PN; Pereira, R; Sander, K; Witney, TH; Zhang, T	1
Abe, K; Hishikawa, N; Huang, Y; Liu, X; Morihara, R; Ohta, Y; Sato, K; Shang, J; Shi, X; Takemoto, M; Yamashita, T	2
Donaldson, PJ; Lim, JC; Martis, RM	1
Brewer, GJ; Digman, MA; Dong, Y; Sameni, S	1
Crum, A; Goswami, R; Norris, KC; Parveen, M; Shen, R; Sinha-Hikim, AP; Sinha-Hikim, I; Tran, P	1
Artunc, F; Cantone, A; Capasso, G; Closs, EI; Daniel, H; Di Giacopo, A; Font-Llitjós, M; Frey-Wagner, I; Gehring, N; Jaenecke, I; Lang, F; Mohebbi, N; Nunes, V; Palacín, M; Rexhepaj, R; Rubio-Aliaga, I; Stange, G; Wagner, CA	1
Antignac, C; Cherqui, S; Courtoy, PJ; Gaide Chevronnay, HP; Guiot, Y; Janssens, V; Levtchenko, E; Marbaix, E; N'Kuli, F; Nevo, N; Pierreux, CE; Van Der Smissen, P	1
Aiba, S; Ito, Y; Kimura, Y; Onami, K; Yamasaki, K; Yamauchi, T	1
Brewer, GJ; Ghosh, D	1
Chiba, Y; Kurihara, S; Mikami, T; Shibakusa, T; Tanaka, KA	1
de Andrade, KQ; de Araújo, OR; dos Santos, JM; Gasparotto, J; Gelain, DP; Goulart, MO; Moura, FA; Santos, JC; Smaniotto, S; Valentim, IB	1
Cherqui, S; Courtoy, PJ; Gaide Chevronnay, HP; Janssens, V; Liao, XH; Pierreux, CE; Refetoff, S; Rocca, CJ; Van Der Smissen, P	1
Albanyan, H; Aloysius, H; Goldfarb, DS; Hu, L; Kholodovych, V; Liang, JJ; Poloni, LN; Sahota, A; Shtukenberg, A; Tischfield, JA; Ward, MD; Yang, M; Yang, Y; Yu, A	1
Beck, JN; Bose, N; Chi, T; Damodar, S; Gerona, RR; Hall, D; Kahn, A; Kapahi, P; Killilea, DW; O'Leary, MN; Parihar, J; Ramanathan, A; Sahota, A; Stoller, ML; Tischfield, J; Yang, M; Yang, S; Zee, J; Zee, T	1
Arcolino, FO; Baelde, HJ; de Witte, PA; Elmonem, MA; Khalil, R; Khodaparast, L; Levtchenko, E; Lowe, M; Morgan, J; Ny, A; Pastore, A; Tylzanowski, P; van den Heuvel, LP	1
Beauséjour, CM; Carbonneau, CL; Couture, R; Ismael, MA; Talbot, S	1
Steketee, JD; Xie, X	1
Brigham, KL; Iyer, SS; Jones, DP; Mora, AL; Ramirez, AM; Ritzenthaler, JD; Rojas, M; Roman, J; Roser-Page, S; Torres-Gonzalez, E	1
Fink, MP; He, X; Killeen, ME; Miki, K; Yang, R	1
Ebersole, JL; Oz, HS	1
Brandsch, C; Eder, K; Hirche, F; Stangl, GI; Weisse, K	1
Kalivas, PW; Knackstedt, LA; Melendez, RI	1
Antignac, C; Bailleux, A; Chol, M; Devuyst, O; Gubler, MC; Kalatzis, V; Morisset, L; Nevo, N	1
Bergman, M; Huttunen, M; Luoto, P; Peräkylä, H; Roivainen, A; Simpura, I; Ujula, T; Wilson, I	1
Rahman, S; Sajja, RK	1
Cherqui, S; Flynn, K; Jester, B; Jester, J; Nien, CJ; Simpson, J	1
Callaerts-Vegh, Z; Carmeliet, P; Collen, D; D'Hooge, R; Dewerchin, M; Lupu, F; Moons, L; Nuyens, D; Silasi-Mansat, R; Souffreau, J; Van Nuffelen, A; Wallays, G	1
Atkins, HL; Forder, RE; Geier, MS; Howarth, GS; Pattanaik, AK; Prisciandaro, LD; Turner, MS	1
Flynn, KJ; Jester, JV; Nien, CJ; Simpson, JL	1
Ankeny, DP; Banerjee, R; Garg, SK; Guan, Z; Kigerl, KA; Lai, W; McTigue, DM; Popovich, PG; Wei, P	1
Darbor, M; Hassanpour, M; Maleki, M; Mard, SA; Neisi, N; Solgi, G	1
Andersen, PM; Brännström, T; Graffmo, KS; Marklund, SL; Zetterström, P	1
Cherqui, S; Harrison, F; Kohn, DB; Rocca, CJ; Salomon, DR; Yeagy, BA	1
Cantin, AM; Cloutier, D; Dufour, EK; Leduc, R; Woods, DE	1
Grosse, J; Nehls, MC; Peters, T; Popp, A; Russ, A; Schlueter, V; Sedlmeier, R; Thaete, C; Wolf, S	1
Chang, HM; Chen, CP; Chimon, GN; Halliwell, B; Ng, YK; Qu, K; Rumpel, H; Seah, AB; Wong, MC; Wong, PT	1
Guan, QH; Liu, XM; Pei, DS; Sun, YF; Zhang, GY; Zhang, QX	1
Abrahamsson, T; Carrier, M; Eliasson, UB; Kengatharan, KM; Pettersson, KS; Wågberg, M	1
Cohen, A; Djaldetti, R; Grimberg, H; Kidron, D; Levin, G; Mayk, A; Melamed, E; Reshef, A; Shirvan, A; Ziv, I	1
Bovee, K; Holtzapple, PG; Rea, CF	1
Athaydes, GA; Dornelles, PK; Feksa, LR; Fleck, RM; Rech, VC; Rodrigues-Junior, V; Wannmacher, CM	1
Cohen, A; Grimberg, H; Levin, G; Reshef, A; Shirvan, A; Shohami, E; Trembovler, V; Ziv, I	1
Craan, AG	1
Butler, JD; Pentchev, PG; Vanier, MT	1
Elvenes, OP; Korvald, C; Nedredal, GI; Nielsen Grymyr, OJ; Revhaug, A; Ytrebø, LM	1
Bac, P; Evrard, P; Gressens, P; Husson, I; Mesplès, B; Vamecq, J	1
Bocock, MA; Zlotkin, SH	1
Beeley, JM; Bell, S; Buchanan, JD; Clark, RJ; Critchley, JA; Edginton, JA; Spurlock, MS; Summerfield, M	1
Bovee, KC; McNamara, PD; Rea, CT; Reynolds, RA; Segal, S	1
Bowring, MA; Foreman, JW; Lee, J; Segal, S; States, B	1
Rauterberg, E; Rauterberg, K	1

Reviews

3 review(s) available for cystine and Disease Models, Animal

Article	Year
Animal models of naturally occurring stone disease. Nature reviews. Urology, 2020, Volume: 17, Issue:12 Topics: Animals; Biomedical Research; Calcium Oxalate; Cats; Cystine; Disease Models, Animal; Dogs; Dolphins; Ferrets; Genetic Predisposition to Disease; Hyperuricemia; Otters; Risk Factors; Struvite; Uric Acid; Urolithiasis	2020
Cystinuria: genetic aspects, mouse models, and a new approach to therapy. Urolithiasis, 2019, Volume: 47, Issue:1 Topics: Amino Acid Transport Systems, Basic; Amino Acid Transport Systems, Neutral; Animals; Chelating Agents; Clinical Trials as Topic; Cystine; Cystinuria; Disease Models, Animal; Drug Development; Female; Humans; Kidney; Kidney Calculi; Male; Mice; Mice, Knockout; Prevalence; Renal Elimination; Severity of Illness Index; Sex Factors	2019
Cystinuria: the disease and its models. Life sciences, 1981, Jan-05, Volume: 28, Issue:1 Topics: Animals; Biological Transport; Carnivora; Cycloleucine; Cystine; Cystinuria; Disease Models, Animal; Dogs; Female; History, 19th Century; History, 20th Century; Humans; Intestinal Mucosa; Kidney Cortex; Kidney Tubules; Lysine; Male; Microvilli; Models, Biological	1981

Other Studies

64 other study(ies) available for cystine and Disease Models, Animal

Article	Year
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49 Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection	2020
Renal and Extra Renal Manifestations in Adult Zebrafish Model of Cystinosis. International journal of molecular sciences, 2021, Aug-30, Volume: 22, Issue:17 Topics: Amino Acid Transport Systems, Neutral; Animals; Cystine; Cystinosis; Disease Models, Animal; Humans; Kidney; Mutation; Phenotype; Zebrafish; Zebrafish Proteins	2021
Oral administration of cystine and theanine attenuates 5-fluorouracil-induced intestinal mucositis and diarrhea by suppressing both glutathione level decrease and ROS production in the small intestine of mucositis mouse model. BMC cancer, 2021, Dec-18, Volume: 21, Issue:1 Topics: Animals; Cystine; Diarrhea; Disease Models, Animal; Drug Therapy, Combination; Fluorouracil; Glutamates; Humans; Intestinal Mucosa; Intestine, Small; Male; Mice; Mucositis; Oxidative Stress; Reactive Oxygen Species	2021
Ex silico engineering of cystine-dense peptides yielding a potent bispecific T cell engager. Science translational medicine, 2022, 05-18, Volume: 14, Issue:645 Topics: Animals; Antibodies, Bispecific; B7-H1 Antigen; CD3 Complex; Cystine; Disease Models, Animal; Humans; Mammals; Mice; Peptides; T-Lymphocytes	2022
A mouse model of type B cystinuria due to spontaneous mutation in FVB/NJcl mice. Urolithiasis, 2022, Volume: 50, Issue:6 Topics: Amino Acid Transport Systems, Basic; Amino Acid Transport Systems, Neutral; Amino Acids, Diamino; Animals; Calculi; Cystine; Cystinuria; Disease Models, Animal; Mice; Mutation	2022
Genistein improves renal disease in a mouse model of nephropathic cystinosis: a comparison study with cysteamine. Human molecular genetics, 2023, 03-20, Volume: 32, Issue:7 Topics: Animals; Cysteamine; Cystine; Cystinosis; Disease Models, Animal; Female; Genistein; Kidney; Kidney Diseases; Mice	2023
Oral administration of 3,3'-diselenodipropionic acid prevents thoracic radiation induced pneumonitis in mice by suppressing NF-kB/IL-17/G-CSF/neutrophil axis. Free radical biology & medicine, 2019, Volume: 145 Topics: A549 Cells; Administration, Oral; Animals; Cystine; Disease Models, Animal; Granulocyte Colony-Stimulating Factor; Humans; Interleukin-17; Lung; Lung Neoplasms; Mice; Neutrophils; NF-kappa B; Organoselenium Compounds; Pneumonia; Propionates; Radiation Injuries; Selenium Compounds; Signal Transduction	2019
Hydrogen sulfide formation in experimental model of acute pancreatitis. Acta biochimica Polonica, 2019, Dec-27, Volume: 66, Issue:4 Topics: Animals; Bile Ducts, Extrahepatic; Cystathionine; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; Cystine; Disease Models, Animal; Gene Expression; Glutathione; Hydrogen Sulfide; Ligation; Male; Mitochondria; Pancreas; Pancreatic Ducts; Pancreatitis; Rats; Rats, Inbred WKY; Sulfurtransferases; Thiosulfate Sulfurtransferase; Transaminases	2019
Tolvaptan treatment of cystine urolithiasis in a mouse model of cystinuria. World journal of urology, 2021, Volume: 39, Issue:1 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Cystine; Cystinuria; Disease Models, Animal; Female; Male; Mice; Tolvaptan; Urinary Calculi; Urolithiasis	2021
Use of Human Induced Pluripotent Stem Cells and Kidney Organoids To Develop a Cysteamine/mTOR Inhibition Combination Therapy for Cystinosis. Journal of the American Society of Nephrology : JASN, 2020, Volume: 31, Issue:5 Topics: Amino Acid Transport Systems, Neutral; Animals; Autophagy; Cell Line; CRISPR-Cas Systems; Cysteamine; Cystine; Cystinosis; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Therapy, Combination; Everolimus; Gene Editing; Heterografts; Humans; Induced Pluripotent Stem Cells; Lysosomes; Mice; Mice, SCID; Organoids; Phenotype; TOR Serine-Threonine Kinases	2020
Oral administration of Cystine and Theanine ameliorates oxaliplatin-induced chronic peripheral neuropathy in rodents. Scientific reports, 2020, 07-29, Volume: 10, Issue:1 Topics: Administration, Oral; Animals; Cold Temperature; Cystine; Disease Models, Animal; Drug Therapy, Combination; Glutamates; Glutathione; Hyperalgesia; Male; Mice; Neoplasms; Oxaliplatin; PC12 Cells; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Sciatic Nerve	2020
CD44 variant inhibits insulin secretion in pancreatic β cells by attenuating LAT1-mediated amino acid uptake. Scientific reports, 2018, 02-12, Volume: 8, Issue:1 Topics: Amino Acid Transport System y+; Amino Acid Transport System y+L; Amino Acid Transport Systems; Animals; Cell Line; Cell Proliferation; Cystine; Diabetes Mellitus, Experimental; Disease Models, Animal; Hyaluronan Receptors; Insulin Secretion; Insulin-Secreting Cells; Large Neutral Amino Acid-Transporter 1; Male; Mice; Mice, Inbred C57BL	2018
Selenocystine inhibits JEG-3 cell growth Journal of cancer research and therapeutics, 2018, Volume: 14, Issue:7 Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Choriocarcinoma; Cystine; Disease Models, Animal; Female; Humans; Mice; Organoselenium Compounds; Oxidative Stress; Reactive Oxygen Species; S Phase Cell Cycle Checkpoints; Xenograft Model Antitumor Assays	2018
Measurement of Tumor Antioxidant Capacity and Prediction of Chemotherapy Resistance in Preclinical Models of Ovarian Cancer by Positron Emission Tomography. Clinical cancer research : an official journal of the American Association for Cancer Research, 2019, 04-15, Volume: 25, Issue:8 Topics: Animals; Antineoplastic Agents; Antioxidants; Biomarkers; Cell Line, Tumor; Cystine; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Humans; Mice; Models, Biological; Neoplasm Grading; Ovarian Neoplasms; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Radiopharmaceuticals; Reactive Oxygen Species; Xenograft Model Antitumor Assays	2019
Clinical and Pathological Benefit of Twendee X in Alzheimer's Disease Transgenic Mice with Chronic Cerebral Hypoperfusion. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2019, Volume: 28, Issue:7 Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Anti-Inflammatory Agents; Antioxidants; Ascorbic Acid; Behavior, Animal; Brain; Cerebrovascular Circulation; Cerebrovascular Disorders; Chronic Disease; Cognition; Cystine; Dietary Supplements; Disease Models, Animal; Female; Glutamine; Inflammation Mediators; Male; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Mutation; Neuroprotective Agents; Oxidative Stress; Plaque, Amyloid	2019
Corneal opacities in mice exposed to repeated contact procedures during ocular examinations. Clinical & experimental optometry, 2020, Volume: 103, Issue:3 Topics: Aging; Animals; Cornea; Corneal Opacity; Cystine; Disease Models, Animal; Disease Progression; Mice; Mice, Knockout; Oxidative Stress	2020
Reversibility of Age-related Oxidized Free NADH Redox States in Alzheimer's Disease Neurons by Imposed External Cys/CySS Redox Shifts. Scientific reports, 2019, 08-02, Volume: 9, Issue:1 Topics: Aging; Alzheimer Disease; Animals; Cell Nucleus; Cells, Cultured; Cellular Senescence; Cysteine; Cystine; Cytoplasm; Disease Models, Animal; Energy Metabolism; Female; Hippocampus; Humans; Intravital Microscopy; Male; Mice; Mice, Transgenic; Microscopy, Fluorescence; Mitochondria; NAD; Neurons; Oxidation-Reduction; Oxidative Stress; Primary Cell Culture	2019
Twendee X Ameliorates Phosphorylated Tau, α-Synuclein and Neurovascular Dysfunction in Alzheimer's Disease Transgenic Mice With Chronic Cerebral Hypoperfusion. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2019, Volume: 28, Issue:10 Topics: alpha-Synuclein; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Antioxidants; Ascorbic Acid; Brain; Cerebrovascular Disorders; Cystine; Dietary Supplements; Disease Models, Animal; Female; Genetic Predisposition to Disease; Glutamine; Male; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Neurovascular Coupling; Phenotype; Phosphorylation; tau Proteins	2019
Long-term supplementation with a cystine-based antioxidant delays loss of muscle mass in aging. The journals of gerontology. Series A, Biological sciences and medical sciences, 2013, Volume: 68, Issue:7 Topics: Aging; AMP-Activated Protein Kinases; Animals; Antioxidants; Apoptosis; Cystine; Disease Models, Animal; JNK Mitogen-Activated Protein Kinases; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Oxidative Stress; Sarcopenia; Treatment Outcome	2013
Differential cystine and dibasic amino acid handling after loss of function of the amino acid transporter b0,+AT (Slc7a9) in mice. American journal of physiology. Renal physiology, 2013, Dec-15, Volume: 305, Issue:12 Topics: Amino Acid Transport Systems, Basic; Amino Acids, Diamino; Animals; Cystine; Cystinuria; Disease Models, Animal; Glomerular Filtration Rate; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Knockout	2013
Time course of pathogenic and adaptation mechanisms in cystinotic mouse kidneys. Journal of the American Society of Nephrology : JASN, 2014, Volume: 25, Issue:6 Topics: Adaptation, Physiological; Amino Acid Transport Systems, Neutral; Animals; Apoptosis; Cell Proliferation; Crystallization; Cystine; Cystinosis; Disease Models, Animal; Disease Progression; Endocytosis; Fanconi Syndrome; Kidney Tubules, Proximal; Low Density Lipoprotein Receptor-Related Protein-2; Lysosomes; Mice; Mice, Inbred C57BL; Mice, Knockout; Proteinuria; Receptors, Cell Surface; Vacuoles	2014
Nonmetal haptens induce ATP release from keratinocytes through opening of pannexin hemichannels by reactive oxygen species. The Journal of investigative dermatology, 2014, Volume: 134, Issue:7 Topics: Adenosine Triphosphate; Animals; Antioxidants; Benzopyrans; Cell Death; Cells, Cultured; Connexins; Cystine; Dermatitis, Contact; Dinitrochlorobenzene; Disease Models, Animal; Female; Haptens; Humans; Irritants; Keratinocytes; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Nickel; Protein Structure, Quaternary; Protein Structure, Tertiary; Pyrimidinones; Reactive Oxygen Species; RNA, Small Interfering	2014
External cys/cySS redox state modification controls the intracellular redox state and neurodegeneration via Akt in aging and Alzheimer's disease mouse model neurons. Journal of Alzheimer's disease : JAD, 2014, Volume: 42, Issue:1 Topics: Aging; Alzheimer Disease; Animals; Cell Death; Cells, Cultured; Cysteine; Cystine; Disease Models, Animal; Extracellular Space; Glutathione; Male; Mice; Mice, Transgenic; NADP; Neurons; Oxidation-Reduction; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species	2014
Cystine improves survival rates in a LPS-induced sepsis mouse model. Clinical nutrition (Edinburgh, Scotland), 2015, Volume: 34, Issue:6 Topics: Animals; Anti-Inflammatory Agents; Cell Line; Cystine; Disease Models, Animal; Glutamates; Humans; Interleukin-10; Interleukin-6; Lipopolysaccharides; Mice; Monocytes; Sepsis; Spleen; Survival Rate	2015
Choline and Cystine Deficient Diets in Animal Models with Hepatocellular Injury: Evaluation of Oxidative Stress and Expression of RAGE, TNF-α, and IL-1β. Oxidative medicine and cellular longevity, 2015, Volume: 2015 Topics: Animals; Body Weight; Catalase; Choline; Cystine; Diet; Disease Models, Animal; Interleukin-1beta; Liver; Male; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Protein Carbonylation; Rats; Rats, Wistar; Receptor for Advanced Glycation End Products; Superoxide Dismutase; Tumor Necrosis Factor-alpha	2015
Hematopoietic Stem Cells Transplantation Can Normalize Thyroid Function in a Cystinosis Mouse Model. Endocrinology, 2016, Volume: 157, Issue:4 Topics: Amino Acid Transport Systems, Neutral; Animals; Cell Differentiation; Cystine; Cystinosis; Disease Models, Animal; Female; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Luminescent Proteins; Lysosomes; Macrophages; Male; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Microscopy, Confocal; Thyroid Gland; Thyrotropin; Transplantation, Homologous	2016
l-Cystine Diamides as l-Cystine Crystallization Inhibitors for Cystinuria. Journal of medicinal chemistry, 2016, Aug-11, Volume: 59, Issue:15 Topics: Administration, Oral; Amino Acid Transport Systems, Basic; Amino Acid Transport Systems, Neutral; Animals; Cystine; Cystinuria; Diamide; Disease Models, Animal; Male; Mice; Mice, Knockout; Models, Molecular; Molecular Structure	2016
α-Lipoic acid treatment prevents cystine urolithiasis in a mouse model of cystinuria. Nature medicine, 2017, Volume: 23, Issue:3 Topics: Amino Acid Transport Systems, Basic; Amino Acid Transport Systems, Neutral; Animals; Cystine; Cystinuria; Disease Models, Animal; Kidney; Mice; Mice, Knockout; Solubility; Thioctic Acid; Urolithiasis; X-Ray Microtomography	2017
Cystinosis (ctns) zebrafish mutant shows pronephric glomerular and tubular dysfunction. Scientific reports, 2017, 02-15, Volume: 7 Topics: Amino Acid Sequence; Amino Acid Transport Systems, Neutral; Animals; Apoptosis; Cystine; Cystinosis; Disease Models, Animal; Gene Knockout Techniques; Glomerular Filtration Rate; Humans; Kidney Glomerulus; Kidney Tubules, Proximal; Locomotion; Lysosomes; Mutation; Phenotype; Podocytes; Zebrafish	2017
Blockade of sensory abnormalities and kinin B(1) receptor expression by N-acetyl-L-cysteine and ramipril in a rat model of insulin resistance. European journal of pharmacology, 2008, Jul-28, Volume: 589, Issue:1-3 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Antioxidants; Blood Glucose; Blood Pressure; Body Weight; Cystine; Diabetes Complications; Disease Models, Animal; Down-Regulation; Drinking; Eating; Glucose; Hyperalgesia; Hypertension; Insulin; Insulin Resistance; Kidney Cortex; Male; Pain Measurement; Ramipril; Rats; Rats, Wistar; Receptor, Bradykinin B1; RNA, Messenger; Sensation; Spinal Cord; Time Factors	2008
Repeated exposure to cocaine alters the modulation of mesocorticolimbic glutamate transmission by medial prefrontal cortex Group II metabotropic glutamate receptors. Journal of neurochemistry, 2008, Volume: 107, Issue:1 Topics: Amino Acids; Animals; Cocaine; Cocaine-Related Disorders; Cystine; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug Administration Schedule; Excitatory Amino Acid Antagonists; Glutamic Acid; Limbic System; Male; Neural Pathways; Prefrontal Cortex; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Synaptic Transmission; Synaptic Vesicles; Ventral Tegmental Area; Xanthenes	2008
Oxidation of extracellular cysteine/cystine redox state in bleomycin-induced lung fibrosis. American journal of physiology. Lung cellular and molecular physiology, 2009, Volume: 296, Issue:1 Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Bronchoalveolar Lavage Fluid; Cysteine; Cystine; Disease Models, Animal; Eating; Extracellular Space; Female; Glutathione; Glutathione Disulfide; Interleukin-6; Lung; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Oxidative Stress; Pulmonary Fibrosis	2009
Prolonged treatment with N-acetylcystine delays liver recovery from acetaminophen hepatotoxicity. Critical care (London, England), 2009, Volume: 13, Issue:2 Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Antidotes; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cystine; Disease Models, Animal; Drug Overdose; Glutathione; Male; Mice; Mice, Inbred C57BL; Time Factors; Treatment Outcome	2009
A novel murine model for chronic inflammatory alveolar bone loss. Journal of periodontal research, 2010, Volume: 45, Issue:1 Topics: Administration, Oral; Alveolar Bone Loss; Alveolar Process; Animals; Chronic Periodontitis; Colon; Cystine; Dextran Sulfate; Disease Models, Animal; Disease Progression; Liver; Mandibular Diseases; Maxillary Diseases; Mice; Mice, Inbred BALB C; Mice, SCID; Periodontium; Time Factors; Trinitrobenzenesulfonic Acid	2010
Lupin protein isolate and cysteine-supplemented casein reduce calcification of atherosclerotic lesions in apoE-deficient mice. The British journal of nutrition, 2010, Volume: 103, Issue:2 Topics: 5'-Nucleotidase; Amino Acids; Animal Feed; Animals; Apolipoproteins E; Atherosclerosis; Calcinosis; Caseins; Cystine; Dietary Proteins; Disease Models, Animal; DNA Primers; Energy Intake; Lipids; Mice; Mice, Knockout; Triglycerides	2010
Ceftriaxone restores glutamate homeostasis and prevents relapse to cocaine seeking. Biological psychiatry, 2010, Jan-01, Volume: 67, Issue:1 Topics: Analysis of Variance; Animals; Antioxidants; Ceftriaxone; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cystine; Disease Models, Animal; Dopamine Uptake Inhibitors; Excitatory Amino Acid Transporter 2; Glutamic Acid; Male; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Self Administration; Time Factors; Tritium	2010
Renal phenotype of the cystinosis mouse model is dependent upon genetic background. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2010, Volume: 25, Issue:4 Topics: Amino Acid Transport Systems, Neutral; Animals; Cystine; Cystinosis; Disease Models, Animal; Female; Kidney Failure, Chronic; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Phenotype; Species Specificity	2010
Matrix metalloproteinase 9 targeting peptides: syntheses, 68Ga-labeling, and preliminary evaluation in a rat melanoma xenograft model. Bioconjugate chemistry, 2010, Sep-15, Volume: 21, Issue:9 Topics: Animals; Cell Line, Tumor; Cystine; Disease Models, Animal; Drug Evaluation; Gallium Radioisotopes; Heterocyclic Compounds, 1-Ring; Kinetics; Matrix Metalloproteinase 9; Melanoma; Peptides; Positron-Emission Tomography; Rats; Tissue Distribution; Transplantation, Heterologous; Tumor Protein, Translationally-Controlled 1	2010
Lobeline and cytisine reduce voluntary ethanol drinking behavior in male C57BL/6J mice. Progress in neuro-psychopharmacology & biological psychiatry, 2011, Jan-15, Volume: 35, Issue:1 Topics: Alcohol Drinking; Analysis of Variance; Animals; Central Nervous System Depressants; Choice Behavior; Cystine; Disease Models, Animal; Dose-Response Relationship, Drug; Drinking; Ethanol; Food Preferences; Male; Mice; Mice, Inbred C57BL; Phenethylamines; Statistics, Nonparametric; Sucrose; Time Factors	2011
Quantitative in vivo and ex vivo confocal microscopy analysis of corneal cystine crystals in the Ctns knockout mouse. Molecular vision, 2011, Volume: 17 Topics: Age Factors; Amino Acid Transport Systems, Neutral; Animals; Cicatrix; Cornea; Crystallization; Cystine; Cystinosis; Disease Models, Animal; Endothelial Cells; Female; Keratinocytes; Leukocyte Common Antigens; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Confocal; Neovascularization, Pathologic; Phalloidine	2011
Notch3 Arg170Cys knock-in mice display pathologic and clinical features of the neurovascular disorder cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy. Arteriosclerosis, thrombosis, and vascular biology, 2011, Volume: 31, Issue:12 Topics: Animals; Arginine; Brain; CADASIL; Capillaries; Cystine; Disease Models, Animal; Fertility; Gene Knock-In Techniques; Mice; Motor Activity; Muscle, Smooth, Vascular; Mutation; Receptor, Notch3; Receptors, Notch	2011
Effects of a Lactobacillus reuteri BR11 mutant deficient in the cystine-transport system in a rat model of inflammatory bowel disease. Digestive diseases and sciences, 2012, Volume: 57, Issue:3 Topics: Animals; Colitis, Ulcerative; Colon; Cystine; Dextran Sulfate; Disease Models, Animal; Limosilactobacillus reuteri; Male; Mucins; Organ Size; Probiotics; Rats; Rats, Sprague-Dawley	2012
Evaluation of topical cysteamine therapy in the CTNS(-/-) knockout mouse using in vivo confocal microscopy. Molecular vision, 2011, Volume: 17 Topics: Administration, Ophthalmic; Amino Acid Transport Systems, Neutral; Animals; Cornea; Crystallization; Cysteamine; Cystine; Cystinosis; Disease Models, Animal; Humans; Mice; Mice, Knockout; Microscopy, Confocal; Ophthalmic Solutions; Treatment Outcome; Visual Acuity	2011
System x(c)(-) regulates microglia and macrophage glutamate excitotoxicity in vivo. Experimental neurology, 2012, Volume: 233, Issue:1 Topics: Animals; Cystine; Disease Models, Animal; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Gene Expression Regulation; Glutamic Acid; Glutathione; Laser Capture Microdissection; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred C57BL; Microglia; Nerve Tissue Proteins; Neurons; Oxidation-Reduction; Quinoxalines; Spinal Cord Diseases	2012
Gastroprotective effect of NaHS against mucosal lesions induced by ischemia-reperfusion injury in rat. Digestive diseases and sciences, 2012, Volume: 57, Issue:6 Topics: Alkynes; Animals; Biopsy, Needle; Cystine; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Gastric Mucosa; Glycine; Immunohistochemistry; Infusions, Intravenous; Interleukin-1beta; Male; Random Allocation; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Reference Values; Reperfusion Injury; RNA, Messenger; Sensitivity and Specificity; Sulfides; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha	2012
Composition of soluble misfolded superoxide dismutase-1 in murine models of amyotrophic lateral sclerosis. Neuromolecular medicine, 2013, Volume: 15, Issue:1 Topics: Amyotrophic Lateral Sclerosis; Animals; Chelating Agents; Chromatography, Gel; Copper; Cysteine; Cystine; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Humans; Hydrophobic and Hydrophilic Interactions; Longevity; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation, Missense; Oxidation-Reduction; Protein Conformation; Protein Folding; Recombinant Proteins; Solubility; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1; Zinc	2013
Hematopoietic stem cell gene therapy for the multisystemic lysosomal storage disorder cystinosis. Molecular therapy : the journal of the American Society of Gene Therapy, 2013, Volume: 21, Issue:2 Topics: Amino Acid Transport Systems, Neutral; Animals; Blotting, Western; Cystine; Cystinosis; Disease Models, Animal; Female; Fluorescent Antibody Technique; Genetic Therapy; Genetic Vectors; Green Fluorescent Proteins; Hematopoietic Stem Cells; Kidney Failure, Chronic; Lentivirus; Luminescent Proteins; Lysosomes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Recombinant Proteins; Transduction, Genetic; Transgenes	2013
Polyethylene glycol conjugation at Cys232 prolongs the half-life of alpha1 proteinase inhibitor. American journal of respiratory cell and molecular biology, 2002, Volume: 27, Issue:6 Topics: alpha 1-Antitrypsin; Animals; Cystine; Disease Models, Animal; Humans; In Vitro Techniques; Leukocyte Elastase; Lung Diseases; Mice; Mice, Inbred C57BL; Molecular Weight; Polyethylene Glycols; Recombinant Proteins; Respiratory Mucosa; Surface-Active Agents	2002
A mouse model for cystinuria type I. Human molecular genetics, 2003, Sep-01, Volume: 12, Issue:17 Topics: Amino Acid Sequence; Amino Acid Transport Systems, Basic; Amino Acids; Animals; Arginine; Carrier Proteins; Chromosome Mapping; Cystine; Cystinuria; Disease Models, Animal; Ethylnitrosourea; Female; Genotype; Lysine; Male; Membrane Glycoproteins; Mice; Mice, Inbred C3H; Mice, Knockout; Molecular Sequence Data; Mutagenesis; Mutation; Ornithine; Phenotype; Sequence Homology, Amino Acid; Urinary Bladder Calculi; Urinary Calculi	2003
High plasma cyst(e)ine level may indicate poor clinical outcome in patients with acute stroke: possible involvement of hydrogen sulfide. Journal of neuropathology and experimental neurology, 2006, Volume: 65, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Amino Acids; Animals; Brain; Cysteine; Cystine; Disease Models, Animal; Female; Humans; Hydrogen Sulfide; Infarction, Middle Cerebral Artery; Male; Middle Aged; Prognosis; Rats; Rats, Wistar; Stroke	2006
Blockade of the translocation and activation of mitogen-activated protein kinase kinase 4 (MKK4) signaling attenuates neuronal damage during later ischemia-reperfusion. Journal of neurochemistry, 2006, Volume: 98, Issue:1 Topics: Analysis of Variance; Animals; Antioxidants; Blotting, Western; Cystine; Disease Models, Animal; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Immunohistochemistry; Immunoprecipitation; Male; MAP Kinase Kinase 4; Neurons; Protein Transport; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction; Subcellular Fractions; Time Factors	2006
N,N-diacetyl-L-cystine improves endothelial function in atherosclerotic Watanabe heritable hyperlipidaemic rabbits. Basic & clinical pharmacology & toxicology, 2007, Volume: 100, Issue:1 Topics: Acetylcholine; Administration, Oral; Animals; Aorta; Atherosclerosis; Cystine; Disease Models, Animal; Endothelium, Vascular; Immunologic Factors; In Vitro Techniques; Male; Pulsatile Flow; Rabbits; Vasodilation; Water Supply	2007
Novel molecular imaging of cell death in experimental cerebral stroke. Brain research, 2007, May-04, Volume: 1144 Topics: Amino Acid Chloromethyl Ketones; Animals; Autoradiography; Cell Death; Cystine; Dansyl Compounds; Diagnostic Imaging; Disease Models, Animal; DNA Fragmentation; In Situ Nick-End Labeling; Mice; Mice, Inbred BALB C; Neurons; Neuroprotective Agents; Quinolines; Rats; Rats, Sprague-Dawley; Stroke; Time Factors; Tritium	2007
Amino acid uptake by kidney and jejunal tissue from dogs with cystine stones. Science (New York, N.Y.), 1969, Dec-19, Volume: 166, Issue:3912 Topics: Amino Acids; Animals; Biological Transport; Cystine; Cystinuria; Disease Models, Animal; Dogs; Glycine; Humans; Intestinal Mucosa; Jejunum; Kidney Cortex; Lysine; Urinary Calculi	1969
Cysteamine prevents inhibition of thiol-containing enzymes caused by cystine or cystine dimethylester loading in rat brain cortex. Metabolic brain disease, 2008, Volume: 23, Issue:2 Topics: Animals; Antioxidants; Cerebral Cortex; Creatine Kinase; Cysteamine; Cystine; Cystinosis; Disease Models, Animal; Enzyme Inhibitors; Lysosomes; Oxidation-Reduction; Oxidative Stress; Pyruvate Kinase; Rats; Rats, Wistar; Sulfhydryl Compounds	2008
Targeting cell death in vivo in experimental traumatic brain injury by a novel molecular probe. Journal of neurotrauma, 2008, Volume: 25, Issue:6 Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Brain; Brain Injuries; Caspases; Cystine; Cytoplasm; Dansyl Compounds; Disease Models, Animal; Disease Progression; DNA Fragmentation; Fluorescent Dyes; In Situ Nick-End Labeling; Mice; Mice, Inbred BALB C; Molecular Structure; Nerve Degeneration; Neurons; Predictive Value of Tests; Staining and Labeling	2008
Niemann-Pick C disease: cystine and lipids accumulate in the murine model of this lysosomal cholesterol lipidosis. Biochemical and biophysical research communications, 1993, Oct-15, Volume: 196, Issue:1 Topics: Animals; Cholesterol; Cystine; Cystinosis; Disease Models, Animal; Glucosylceramides; Humans; Lipid Metabolism; Liver; Lysosomes; Mice; Mice, Inbred BALB C; Mice, Mutant Strains; Niemann-Pick Diseases; Sphingomyelins; Tissue Distribution	1993
N-acetylcysteine increases cerebral perfusion pressure in pigs with fulminant hepatic failure. Critical care medicine, 2001, Volume: 29, Issue:10 Topics: Animals; Biological Transport; Cerebrovascular Circulation; Cystine; Disease Models, Animal; Female; Hemodynamics; Infusions, Intravenous; Liver Failure; Oxygen Consumption; Reference Values; Sensitivity and Specificity; Swine	2001
Melatoninergic neuroprotection of the murine periventricular white matter against neonatal excitotoxic challenge. Annals of neurology, 2002, Volume: 51, Issue:1 Topics: Animals; Animals, Newborn; Antioxidants; Cell Death; Cerebral Palsy; Cystine; Denervation; Disease Models, Animal; Excitatory Amino Acid Agonists; Free Radical Scavengers; Humans; Hypothermia, Induced; Ibotenic Acid; Infant, Newborn; Leukomalacia, Periventricular; Melatonin; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neocortex; Neuroprotective Agents; Neurotoxins; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; RNA, Messenger; Tetrahydronaphthalenes; Tryptamines	2002
Hepatic sulfur amino acid metabolism in rats with chronic renal failure. The Journal of nutrition, 1990, Volume: 120, Issue:7 Topics: Amino Acids, Sulfur; Animals; Anorexia; Creatinine; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cystine; Disease Models, Animal; Growth Disorders; Kidney Failure, Chronic; Liver; Male; Methionine; Methionine Adenosyltransferase; Organ Size; Rats; Rats, Inbred Strains; Taurine; Urea; Uremia	1990
Evaluation of N-acetylcysteine and methylprednisolone as therapies for oxygen and acrolein-induced lung damage. Environmental health perspectives, 1990, Volume: 85 Topics: Acrolein; Administration, Inhalation; Aldehydes; Animals; Cystine; Disease Models, Animal; Injections, Intravenous; Lung Diseases; Methylprednisolone; Organ Size; Oxygen; Rats; Rats, Inbred Strains	1990
Cystinuria in dogs: comparison of the cystinuric component of the Fanconi syndrome in basenji dogs to isolated cystinuria. Metabolism: clinical and experimental, 1989, Volume: 38, Issue:1 Topics: Amino Acids; Animals; Biological Transport; Cystine; Cystinuria; Disease Models, Animal; Dogs; Fanconi Syndrome; Female; Glomerular Filtration Rate; Glucose; Kidney; Kinetics; Male; Microvilli; Sodium	1989
Effect of cystine dimethylester on renal solute handling and isolated renal tubule transport in the rat: a new model of the Fanconi syndrome. Metabolism: clinical and experimental, 1987, Volume: 36, Issue:12 Topics: Amino Acids; Animals; Cystine; Cystinosis; Disease Models, Animal; Fanconi Syndrome; Humans; Kidney Tubules, Proximal; Male; Methylglucosides; Rats; Rats, Inbred Strains	1987
[Experimental investigations of the causes of juvenile slipped epiphysis of the head of femur (author's transl)]. Zeitschrift fur Orthopadie und ihre Grenzgebiete, 1974, Volume: 112, Issue:1 Topics: Animals; Cartilage; Cystine; Disease Models, Animal; Epiphyses, Slipped; Femur; Femur Head; Lipid Metabolism; Rabbits; Rats; Selenium; Sulfhydryl Compounds; Tibia	1974