cystic fibrosis transmembrane conductance regulator (505-511) has been researched along with Cystic Fibrosis in 14 studies
*Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 9 (64.29) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bompadre, SG; Kopeikin, Z; Yang, HY; Yuksek, Z | 1 |
| Mayor, S | 1 |
| Ittenbach, RF; McBride, MG; Paridon, SM; Schall, JI; Stallings, VA; Zemel, BS | 1 |
| Cooper-Knock, J; Garrard, K; Lo, C; Martindale, J; Shaw, P; Williams, T | 1 |
| Banks-Schlegel, SP; Guggino, WB | 1 |
| Aebischer, CC; Keller, BM; Kraemer, R; Schöni, MH | 1 |
| Cabello, GM; Cabello, PH; Fernandes, O; Llerena, JC; Lopez-Camelo, JS | 1 |
| Nau, JY | 1 |
| Ratjen, F | 1 |
| Ahrens, RC; Aitken, ML; Hilliard, KA; Kelley, TJ; Konstan, MW; Launspach, J; McCarty, NA; Milgram, LJ; Regelmann, WE; Standaert, TA; Teresi, M; Tuthill, C; Weatherly, MR | 1 |
| Brooks, JG; Detzer, M; Kahn, R; Lever, T; Maddock, J; O'Connor, GT; Quinton, HB; Robichaud, P | 1 |
| Bush, A; Crowley, S | 1 |
| Borowitz, D; Cimino, M; Simon, D | 1 |
| Chan, HC; Dedman, JR; Hazarika, P; Kaetzel, MA; Nelson, DJ | 1 |
2 review(s) available for cystic fibrosis transmembrane conductance regulator (505-511) and Cystic Fibrosis
| Article | Year |
|---|---|
Macromolecular interactions and ion transport in cystic fibrosis.
Topics: Cell Membrane; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Forecasting; Humans; Ion Transport; Macromolecular Substances; Mutation; Needs Assessment; Peptide Fragments; Protein Folding; Protein Interaction Mapping; Research | 2004 |
New pulmonary therapies for cystic fibrosis.
Topics: Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Genetic Therapy; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lung Diseases; Peptide Fragments; Sodium Channel Blockers; Treatment Outcome | 2007 |
1 trial(s) available for cystic fibrosis transmembrane conductance regulator (505-511) and Cystic Fibrosis
| Article | Year |
|---|---|
A phase I randomized, multicenter trial of CPX in adult subjects with mild cystic fibrosis.
Topics: Adolescent; Adult; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; Female; Humans; Male; Membrane Potentials; Mutation, Missense; Nasal Mucosa; Peptide Fragments; Purinergic P1 Receptor Antagonists; Regression Analysis; Research Design; Sweat; Treatment Outcome; Xanthines | 2002 |
11 other study(ies) available for cystic fibrosis transmembrane conductance regulator (505-511) and Cystic Fibrosis
| Article | Year |
|---|---|
Combined effects of VX-770 and VX-809 on several functional abnormalities of F508del-CFTR channels.
Topics: Adenosine Triphosphate; Aminophenols; Aminopyridines; Benzodioxoles; Carrier Proteins; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Humans; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Patch-Clamp Techniques; Peptide Fragments; Quinolones | 2014 |
Drug combination that corrects deficient protein in cystic fibrosis improves lung function.
Topics: Aminophenols; Aminopyridines; Benzodioxoles; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Drug Therapy, Combination; Humans; Peptide Fragments; Quinolones; Randomized Controlled Trials as Topic; Respiratory Function Tests | 2015 |
Clinical and genetic correlates of exercise performance in young children with cystic fibrosis.
Topics: Anthropometry; Child; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; DNA Mutational Analysis; Exercise Test; Female; Genotype; Heterozygote; Humans; Male; Malnutrition; Nutritional Status; Peptide Fragments; Respiratory Function Tests | 2010 |
Concurrent amyotrophic lateral sclerosis and cystic fibrosis supports common pathways of pathogenesis.
Topics: Adult; Amyotrophic Lateral Sclerosis; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; DNA-Binding Proteins; Female; Humans; Mutation; Peptide Fragments; RNA Splicing | 2013 |
Growth in prepubertal children with cystic fibrosis, homozygous for the Delta F508 mutation.
Topics: Adolescent; Analysis of Variance; Body Height; Body Mass Index; Body Weight; Child; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Female; Forced Expiratory Volume; Genotype; Growth Disorders; Homozygote; Hospitals, Pediatric; Humans; Linear Models; Longitudinal Studies; Male; Maximal Midexpiratory Flow Rate; Mutation; Peptide Fragments; Retrospective Studies; Switzerland; Vital Capacity | 2003 |
Haplotype distribution of and linkage disequilibrium between four polymorphic markers near the CFTR locus in Brazilian cystic fibrosis patients.
Topics: Africa South of the Sahara; Alleles; Brazil; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Genetics, Population; Haplotypes; Humans; Linkage Disequilibrium; Mediterranean Islands; Peptide Fragments; Polymorphism, Genetic | 2005 |
[Prenatal testing for cystic fibrosis].
Topics: Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Female; Humans; Mutation; Peptide Fragments; Pregnancy; Prenatal Diagnosis | 2006 |
Case-mix adjustment for evaluation of mortality in cystic fibrosis.
Topics: Age Factors; Child; Child, Preschool; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Ethnicity; Female; Genotype; Humans; Infant; Male; Multivariate Analysis; Peptide Fragments; Proportional Hazards Models; Racial Groups; Registries; Risk Adjustment; Sex Factors; Socioeconomic Factors; Survival Analysis; United States | 2002 |
Cystic fibrosis: keeping it in the family.
Topics: Adult; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Female; Fertility; Homozygote; Humans; Infant; Male; Peptide Fragments; Phenotype; Pregnancy; Sweat | 2002 |
Normal volume of distribution of tobramycin in a mother and daughter with a CFTR splice mutation (1717 - 1G --> A).
Topics: Adult; Anti-Bacterial Agents; Child; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Female; Humans; Mutation; Peptide Fragments; Tobramycin | 2002 |
Antibody against a cystic fibrosis transmembrane conductance regulator-derived synthetic peptide inhibits anion currents in human colonic cell line T84.
Topics: Anions; Antibodies; Biological Transport; Blotting, Western; Calcium; Cations, Divalent; Cell Line; Chlorides; Colon; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Diffusion; Humans; Membrane Proteins; Oligopeptides; Peptide Fragments; Peptides | 1992 |