cysteine-glutathione-disulfide has been researched along with Chemical-and-Drug-Induced-Liver-Injury* in 1 studies
1 other study(ies) available for cysteine-glutathione-disulfide and Chemical-and-Drug-Induced-Liver-Injury
Article | Year |
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Hepatoprotection by L-cysteine-glutathione mixed disulfide, a sulfhydryl-modified prodrug of glutathione.
L-Cysteine-glutathione disulfide, a ubiquitous substance present in mammalian cells, was shown to be highly effective in protecting mice against acetaminophen-induced hepatotoxicity. Since the corresponding D-cysteine-glutathione disulfide was totally ineffective in this regard, an enzymatic mechanism that provides glutathione directly to cells is postulated. Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Animals; Chemical and Drug Induced Liver Injury; Cysteine; Free Radical Scavengers; Glutathione; Mice; Prodrugs | 2003 |