cysteine and Protein Aggregation, Pathological

cysteine has been researched along with Protein Aggregation, Pathological in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's9 (50.00)24.3611
2020's9 (50.00)2.80

Authors

AuthorsStudies
Atieh, TB; Baum, J; Hoop, CL; Roth, J; Yang, X1
Hsu, SD; Puri, S1
Huang, L; Li, W; Li, Y; Song, C; Sun, X; Wang, H; Wang, P1
Aartsma-Rus, A; Baas, F; Brouwer, G; Dauwerse, JG; Gravesteijn, G; Hegeman, I; Jost, CR; Kruit, MC; Lesnik Oberstein, SAJ; Mulder, AA; Overzier, M; Rutten, JW; Terwindt, GM; van Duinen, SG1
Guo, Z; Yoon, A; Zhen, J1
Cieplak, P; Deal, AK; Ghatak, S; Han, X; Lipton, SA; Martinez, FJ; Nakamura, T; Oh, CK; Pirie, E; Scott, HR; Yates, JR; Yeo, GW; Zhang, X1
Anand, BG; Brünnert, D; Goyal, P; Hanschmann, EM; Kar, K; Kateriya, S; Kaushik, V; Sharma, PK1
Arboix, A; Fernández-Cadenas, I; Muiño, E1
Gao, L; Jin, J; Liu, P; Lu, WH; Lv, J; Xie, X; Zhang, H1
Chen, H; Chen, J; Li, S; Liu, Q; Liu, S; Ni, J1
Fan, X; Monnier, VM; Ramkumar, S; Wang, B; Yang, S1
Huffer, KE; Lacy, SM; Lee, JC; McGlinchey, RP; Sidransky, E; Tayebi, N1
Cao, Y; Huang, Y; Lang, M; Lu, B; Wu, Z; Zhou, B1
Araki, T; Fujiwara, N; Masutani, H; Nagano, S; Takahashi, Y; Urushitani, M; Yamamoto, K1
Khandelwal, P; Maurya, S; Patel, BK; Prasad, A; Sharma, N; Sivalingam, V; Yadav, SC1
Kang, H; Li, B; Liu, S; Meng, XY; Zhao, L; Zhou, R1
Akaike, T; Kasamatsu, S; Matsunaga, T; Motohashi, H; Nishida, M; Nishimura, A1
Chamberlain, LH; Diez-Ardanuy, C; Greaves, J; Munro, KR; Tomkinson, NC1

Reviews

2 review(s) available for cysteine and Protein Aggregation, Pathological

ArticleYear
Contribution of "Omic" Studies to the Understanding of Cadasil. A Systematic Review.
    International journal of molecular sciences, 2021, Jul-08, Volume: 22, Issue:14

    Topics: CADASIL; Cysteine; Gastrointestinal Microbiome; Gene Frequency; Gene Ontology; Genetic Association Studies; Genome-Wide Association Study; Genomics; Humans; Models, Molecular; Mutation; Nerve Tissue Proteins; Prevalence; Prognosis; Protein Aggregation, Pathological; Protein Conformation; Protein Domains; Proteomics; Receptor, Notch3; Sequence Analysis, DNA; Transcriptome

2021
Redox regulation of electrophilic signaling by reactive persulfides in cardiac cells.
    Free radical biology & medicine, 2017, Volume: 109

    Topics: Animals; Cardiomyopathies; Cyclic GMP; Cysteine; Disulfides; Gene Expression Regulation; GTP-Binding Proteins; Humans; Myocardium; Myocytes, Cardiac; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Protein Aggregation, Pathological; Reactive Oxygen Species; Signal Transduction; Sulfides

2017

Other Studies

16 other study(ies) available for cysteine and Protein Aggregation, Pathological

ArticleYear
DJ-1 Acts as a Scavenger of α-Synuclein Oligomers and Restores Monomeric Glycated α-Synuclein.
    Biomolecules, 2021, 10-06, Volume: 11, Issue:10

    Topics: Acetylation; alpha-Synuclein; Cysteine; Glycation End Products, Advanced; Humans; Magnetic Resonance Spectroscopy; Neurons; Parkinson Disease; Protein Aggregation, Pathological; Protein Deglycase DJ-1; Protein Multimerization

2021
Oxidation of catalytic cysteine of human deubiquitinase BAP1 triggers misfolding and aggregation in addition to functional loss.
    Biochemical and biophysical research communications, 2022, 04-09, Volume: 599

    Topics: Carcinogenesis; Circular Dichroism; Cysteine; Disulfides; Humans; Hydrogen Deuterium Exchange-Mass Spectrometry; Hydrogen Peroxide; Oxidation-Reduction; Oxidative Stress; Protein Aggregation, Pathological; Protein Domains; Protein Folding; Spectrometry, Fluorescence; Tumor Suppressor Proteins; Ubiquitin Thiolesterase

2022
A novel cysteine-sparing G73A mutation of NOTCH3 in a Chinese CADASIL family.
    Neurogenetics, 2020, Volume: 21, Issue:1

    Topics: Asian People; CADASIL; Cell Survival; China; Cysteine; Female; HEK293 Cells; Humans; Male; Middle Aged; Pedigree; Protein Aggregation, Pathological; Receptor, Notch3

2020
Naturally occurring NOTCH3 exon skipping attenuates NOTCH3 protein aggregation and disease severity in CADASIL patients.
    Human molecular genetics, 2020, 07-21, Volume: 29, Issue:11

    Topics: Adult; Aged; Biopsy; CADASIL; CRISPR-Cas Systems; Cysteine; Exons; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Protein Aggregation, Pathological; Receptor, Notch3; Severity of Illness Index; Skin; White Matter

2020
Segmental structural dynamics in Aβ42 globulomers.
    Biochemical and biophysical research communications, 2021, 03-19, Volume: 545

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Cysteine; Electron Spin Resonance Spectroscopy; Humans; Models, Molecular; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Peptide Fragments; Protein Aggregates; Protein Aggregation, Pathological; Protein Conformation; Protein Multimerization; Protein Stability; Spin Labels

2021
S-nitrosylated TDP-43 triggers aggregation, cell-to-cell spread, and neurotoxicity in hiPSCs and in vivo models of ALS/FTD.
    Proceedings of the National Academy of Sciences of the United States of America, 2021, 03-16, Volume: 118, Issue:11

    Topics: Amyotrophic Lateral Sclerosis; Brain; Cysteine; DNA-Binding Proteins; Frontotemporal Dementia; Humans; Induced Pluripotent Stem Cells; Motor Neurons; Nitric Oxide; Protein Aggregation, Pathological; Reactive Nitrogen Species; RNA Processing, Post-Transcriptional; S-Nitrosothiols; Stress, Physiological

2021
The intrinsic amyloidogenic propensity of cofilin-1 is aggravated by Cys-80 oxidation: A possible link with neurodegenerative diseases.
    Biochemical and biophysical research communications, 2021, 09-10, Volume: 569

    Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid; Amyloidogenic Proteins; Cofilin 1; Computer Simulation; Cysteine; Humans; Models, Molecular; Mutation; Neurodegenerative Diseases; Oxidation-Reduction; Propensity Score; Protein Aggregation, Pathological; Protein Stability; Protein Unfolding; Sequence Homology, Amino Acid

2021
Propensity of IgA to self-aggregate via tailpiece cysteine-471 and treatment of IgA nephropathy using cysteamine.
    JCI insight, 2021, 10-08, Volume: 6, Issue:19

    Topics: Animals; Cysteamine; Cysteine; Cystine Depleting Agents; Disease Models, Animal; Glomerulonephritis, IGA; Humans; Immunoglobulin A; Immunoglobulin J-Chains; Kidney Glomerulus; Mice; Protein Aggregation, Pathological; Rats

2021
Blocking the Thiol at Cysteine-322 Destabilizes Tau Protein and Prevents Its Oligomer Formation.
    ACS chemical neuroscience, 2018, 07-18, Volume: 9, Issue:7

    Topics: Alzheimer Disease; Animals; Apoptosis; Brain; Cysteine; Escherichia coli; HEK293 Cells; Humans; Hydrogen Peroxide; Mice, Transgenic; Protein Aggregation, Pathological; Protein Stability; Recombinant Proteins; Selenoprotein W; Sulfhydryl Compounds; tau Proteins

2018
Reactive cysteine residues in the oxidative dimerization and Cu
    Biochimica et biophysica acta. Molecular basis of disease, 2018, Volume: 1864, Issue:11

    Topics: Adolescent; Age Factors; Aged; Cataract; Cations, Divalent; Child; Child, Preschool; Copper; Cysteine; Disulfides; gamma-Crystallins; Glutathione; Humans; Lens, Crystalline; Molecular Docking Simulation; Mutagenesis, Site-Directed; Mutation; Oxidative Stress; Protein Aggregation, Pathological; Protein Multimerization; Recombinant Proteins

2018
C-terminal α-synuclein truncations are linked to cysteine cathepsin activity in Parkinson's disease.
    The Journal of biological chemistry, 2019, 06-21, Volume: 294, Issue:25

    Topics: alpha-Synuclein; Amyloid; Animals; Cathepsin B; Cathepsin L; Cysteine; Dopaminergic Neurons; Humans; Lysosomes; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Parkinson Disease; Protein Aggregation, Pathological; Rats

2019
Zinc binding directly regulates tau toxicity independent of tau hyperphosphorylation.
    Cell reports, 2014, Aug-07, Volume: 8, Issue:3

    Topics: Animals; Cysteine; Drosophila; Histidine; Humans; Mutation; Phosphorylation; Protein Aggregation, Pathological; Protein Binding; tau Proteins; Tauopathies; Zinc

2014
A cysteine residue affects the conformational state and neuronal toxicity of mutant SOD1 in mice: relevance to the pathogenesis of ALS.
    Human molecular genetics, 2015, Jun-15, Volume: 24, Issue:12

    Topics: Amino Acid Substitution; Amyotrophic Lateral Sclerosis; Animals; Cysteine; Disease Models, Animal; Gene Dosage; Humans; Mice; Mice, Transgenic; Motor Neurons; Mutation; Oxidation-Reduction; Phenotype; Physical Exertion; Protein Aggregation, Pathological; Protein Conformation; Protein Folding; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1; Transgenes

2015
New insights into in vitro amyloidogenic properties of human serum albumin suggest considerations for therapeutic precautions.
    FEBS letters, 2015, Dec-21, Volume: 589, Issue:24 Pt B

    Topics: Amyloidogenic Proteins; Chromatography, Gel; Cysteine; Detergents; Dimerization; Drug Carriers; Humans; Hydrogen Peroxide; Microscopy, Atomic Force; Microscopy, Electron, Transmission; Molecular Weight; Oxidants; Oxidation-Reduction; Plasma Substitutes; Protein Aggregation, Pathological; Protein Stability; Recombinant Proteins; Sarcosine; Serum Albumin; Serum Albumin, Human

2015
EGCG in Green Tea Induces Aggregation of HMGB1 Protein through Large Conformational Changes with Polarized Charge Redistribution.
    Scientific reports, 2016, Feb-22, Volume: 6

    Topics: Binding Sites; Catechin; Cysteine; HMGB1 Protein; Humans; Molecular Conformation; Molecular Dynamics Simulation; Molecular Structure; Protein Aggregates; Protein Aggregation, Pathological; Protein Binding; Protein Domains; Protein Multimerization; Static Electricity; Tea

2016
A cluster of palmitoylated cysteines are essential for aggregation of cysteine-string protein mutants that cause neuronal ceroid lipofuscinosis.
    Scientific reports, 2017, 01-31, Volume: 7, Issue:1

    Topics: Cysteine; HSP40 Heat-Shock Proteins; Humans; Lipoylation; Membrane Proteins; Mutation, Missense; Neuronal Ceroid-Lipofuscinoses; Protein Aggregation, Pathological; Protein Processing, Post-Translational; Sequence Deletion

2017