cysteine and Neoplasms

cysteine has been researched along with Neoplasms in 286 studies

Research

Studies (286)

TimeframeStudies, this research(%)All Research%
pre-199033 (11.54)18.7374
1990's16 (5.59)18.2507
2000's59 (20.63)29.6817
2010's98 (34.27)24.3611
2020's80 (27.97)2.80

Authors

AuthorsStudies
Dong, Y; Li, D; Liu, J; Yang, W; Zhang, M; Zhang, X; Zhao, K1
El-Mesery, M; Frackmann, K; Koderer, C; Kübler, AC; Linz, C; Ries, E; Schmitz, W; Seher, A; Völter, MF; Wünsch, AC1
La Serra, MA; Marino, T; Prejanò, M; Romeo, I; Russo, N1
Biggin, PC; Deme, JC; Kolokouris, D; Kuteyi, G; Lea, SM; Newstead, S; Parker, JL1
Gureeva, TA; Kugaevskaya, EV; Solovyova, NI; Timoshenko, OS1
Chang, WA; Cheng, CH; Chuang, CH; Hsu, YL; Hung, JY; Sheu, CC; Tsai, MJ; Wu, KL1
Björnstedt, M; Björnstedt, S; Razaghi, A; Selvam, AK; Szekerczés, T1
Klein Geltink, RI; Parker, SJ; Sorensen, PH; Zhang, HF1
He, W; Li, S; Liu, X; Meng, X; Peng, L; Xie, W; Yin, J1
Elmezayen, A; Li, L; Meyer, C; Westover, K; Zhou, ZW1
Alomary, MN; Ansari, MA; Chen, HJ; Jahangir, M; Ji, XY; Khan, NH; Khattak, S; Muhammad, P; Rauf, MA; Wu, DD; Zhang, CY; Zhang, QQ1
Davidson, RB; De, K; Feng, K; Morrell-Falvey, J; Muchero, W; Pal, D; Parks, JM; Shanks, CM; Yates, TB1
Huang, Q; Wu, M; Wu, X; Xia, Y; Zhang, Y1
Fan, Y; Liu, X; Tan, X; Tu, X; Wang, Y; Zhao, H1
Chen, H; Chen, Y; Li, X; Liang, L; Wang, D; Xiang, H; You, C; Zhao, Y1
Basilion, JP; Bijlstra, OD; Burggraaf, J; Fallert, LC; Hilling, DE; Kuppen, PJK; Linders, DGJ; March, TL; Pool, M; Straight, B; Vahrmeijer, AL; Valentijn, ARPM; Walker, E1
Bhattacharyya, C; Chakraborty, S; Sengupta, R1
Bravo, DD; Chee, E; Corr, N; Dere, E; Fei, M; Huang, H; Leipold, DD; Liang, WC; Masih, S; McNamara, E; Ohri, R; Shin, G; Vollmar, BS; Wang, J; Wu, C; Wu, Y; Yan, M; Yu, L; Zhang, G1
Araki, M; Ikegami, M; Kanno, SI; Kohno, T; Kohsaka, S; Mano, H; Matsumoto, S; Miyoshi, K; Nakaoku, T; Okamoto, A; Okuno, Y; Otsuka, A; Sagae, Y; Sekijima, M; Tabata, J; Ui, A; Yasui, A; Yoshino, R1
Bai, C; Fang, M; He, Z; Huang, L; Jiang, Q; Jin, C; Lu, S; Qin, F; Sun, J; Wang, Y; Xu, X; Yan, Q; Zhang, T; Zhang, Y; Zhao, C1
Guiley, KZ; Shokat, KM1
Daly, SM; Newfeld, SJ; Peraza, A1
Alshahrani, A; Ding, N; Hao, Y; Jiang, H; Thapa, P; Wei, Q1
Liao, L; Liu, Z; Wang, P; Wei, J; Xiao, L; Yan, X; Zhou, D1
Dong, YB; Guan, Q; Zhou, LL; Zhou, W1
Ji, X; Liu, J; Lu, X; Tao, Y; Wang, J; Wang, N; Zhang, J; Zhao, W1
Hlozkova, K; Safrhansova, L; Starkova, J1
Addeo, A; Banna, G; Desai, A; Friedlaender, A; Liu, SV; Parikh, K; Subbiah, V1
Abbott, JR; Arnhof, H; Böttcher, J; Bröker, J; Gerstberger, T; Gmachl, M; Gmaschitz, G; Gollner, A; Herdeis, L; Kessler, D; Krämer, O; Little, A; Mantoulidis, A; Mayer, M; McConnell, DB; Mischerikow, N; Phan, J; Rudolph, D; Rumpel, K; Savarese, F; Smethurst, C; Sun, Q; Treu, M; W Fesik, S; Waterson, AG; Weinstabl, H; Wunberg, T1
Chen, D; Chen, T; Chen, W; Gu, Z; Jiang, B; Li, F; Liu, S; Liu, X; Yu, W; Zhao, Y1
Guria, UN; Halder, S; Jana, K; Mahapatra, AK; Maiti, K; Mandal, D; Samanta, SK1
Chai, R; Chu, B; Cui, W; Du, L; Fu, X; Gu, W; Huang, B; Liang, CH; Liu, D; Wang, X; Yang, L; Yang, Y; Yin, C; Zhang, X; Zhang, Y; Zhuang, X1
Irie, H; Koizumi, M; Matsuda, M; Mochizuki, S; Morita, K1
Dong, CC; Qin, T; Ruan, H; Wu, G; Yang, JR; Zhang, QH; Zhang, Y; Zhao, JH; Zhu, Z1
Ackerman, HD; Caldwell, S; Combs, JA; DeNicola, GM; Falzone, A; Flores, ER; Prieto-Farigua, N; Yoon, SJ1
Chen, Y; Ding, W; Guo, Z; He, W; Li, Y; Wu, Y; Yao, S1
Ketteler, R; Luft, C; Pilger, DRB1
Ayala-Santos, C; Chen, A; Choy, TJ; Cregg, J; Cuevas-Navarro, A; Dinglasan, N; Evans, J; Gill, AL; Gould, A; Kim, D; Knox, JE; Koltun, ES; Li, C; Lito, P; Lucas, J; Marquez, A; Milin, A; Nichols, R; Pourfarjam, Y; Saldajeno-Concar, M; Salvador, A; Sang, B; Schulze, CJ; Seamon, KJ; Singh, M; Smith, JAM; Tomlinson, A; Vemulapalli, V; Vides, A; Wang, Z; Weller, C; Whalen, DM; Wildes, D; Yang, YC; Zhao, Y; Zhong, M1
Chen, CW; Li, M; Zhang, L1
Cravatt, BF; DeMeester, KE; Huang, TP; Li, H; Liu, DR; Lu, B; Lykke-Andersen, J; Ma, T; Melillo, B; Njomen, E; Ogasawara, D; Remsberg, JR; Schreiber, SL; Simon, GM; Won, SJ; Zhao, KT1
Díaz-Perlas, C; Escobar-Rosales, M; Lucana, MC; Lucchi, R; Oller-Salvia, B1
Chen, S; Dai, C; Feng, Y; He, Z; Hou, Z; Li, S; Li, Z; Lian, C; Liang, H; Liu, N; Liu, Z; Lu, F; Luo, Q; Ma, Y; Song, C; Wang, Y; Wu, J; Xing, Y; Ye, Y; Yin, F; Zhang, M; Zhong, W; Zhu, L1
Nakanishi, H; Stoka, V; Turk, V; Vasiljeva, O1
Brimble, MA; Dunbar, PR; Lu, BL; Verdon, DJ; Williams, GM1
DeNicola, GM; Ward, NP1
Balta, E; Hardt, R; Hillmer, S; Hübner, K; Jahraus, B; Kirchgessner, H; Liang, J; Meuer, S; Orlik, C; Samstag, Y; Wabnitz, GH1
Korolev, DO; Petushkova, AI; Savvateeva, LV; Zamyatnin, AA1
Ali, TFS; Ciftci, HI; Ellakwa, DE; Fujita, M; Ito, A; Koga, R; Nakata, A; Okamoto, Y; Otsuka, M; Radwan, MO; Tateishi, H; Yoshida, M1
Jeon, J; Mushtaq, S; Yun, SJ1
Berisa, M; Cross, JR; Qin, W; Schwörer, S; Thompson, CB; Zhu, J1
Jia, P; Li, Z; Liang, C; Liu, C; Sheng, W; Yu, Y; Zhang, H; Zhang, X; Zhu, B; Zhu, H1
Birsoy, K; Weber, R1
Agbana, YL; Karou, SD; Kassegne, K; Kuang, Y; Ni, Y; Zhang, Q; Zhou, M; Zhu, Y1
Fraser, NJ; Fuller, W; Howie, J; Wypijewski, KJ1
Delfarah, A; Graham, NA; Joly, JH; Parrish, S; Phung, PS1
Ghanemi, A; St-Amand, J; Yoshioka, M1
Battino, M; Giampieri, F; Llopis, J; Navarro-Hortal, MD; Quiles, JL; Sánchez-González, C; Varela-López, A; Vera-Ramírez, L; Xiao, J1
Bausbacher, T; Fülöp, A; Gillandt, H; Hopf, C; Rittner, M; Rizzo, S; Zhou, Q1
Hölzen, L; Parigiani, MA; Reinheckel, T1
Amante, R; Badr, CE; Boukhali, M; Chen, JW; Chiu, NHL; da Hora, CC; Fitzsimons, E; Haas, W; Kirov, AB; Maksoud, S; Mazitschek, R; Nakano, I; Nibbs, AE; Tabet, E; Tannous, BA1
Jakoš, T; Kos, J; Pečar Fonović, U; Pišlar, A; Švajger, U1
Kosaloglu-Yalcin, Z; Moore, E; Peters, B; Robbins, PF; Rosenberg, SA; Sachs, A; Sette, A; Sidney, J1
Hua, X; Huang, H; Wang, Z; Xie, X; Yang, X1
Ariaans, GJA; Beusker, PH; Blomenröhr, M; Coumans, RGE; Dokter, WHA; Groothuis, PG; Kokke, BPA; Renart Verkerk, P; Schouten, J; Spijker, HJ; Timmers, CM; Ubink, R; van der Lee, MMC1
Athineos, D; Bauer, C; Blyth, K; Maddocks, ODK; Newman, AC; Uribe, AH; Zhang, T1
Amin Nordin, S; Joseph, N; Nandagopal Ms, G; Subramanian, MS; Thilakavathy, K1
Huttner, D; Meller, A; Ohayon, S; Zrehen, A1
Deng, Y; Lang, Y; Xue, H; Yang, X; Zhang, Y1
Chao, J; Cheng, F; Huang, Y; Huo, F; Yin, C; Zhang, Y1
Han, F; Lin, W; Ma, Y; Min, J1
Klimpel, A; Krüger, M; Neundorf, I; Stillger, K; Wiederstein, JL1
Bonifácio, VDB; Pereira, SA; Serpa, J; Vicente, JB1
Ambrogio, C; Kramer-Drauberg, M1
Chatterji, A; Sengupta, R1
Dubey, VK; Prerna, K1
Doyle, SK; Henley, MJ; Koehler, AN1
Peyruchaud, O; Saier, L1
Belaidi, AA; Lei, P; Li, H; Tuo, QZ; Xu, S; Yan, HF; Zou, T1
Chibh, S; Katoch, V; Khanam, F; Kour, A; Kundu, GC; Panda, JJ; Prakash, B; Singh, M; Yadav, AS1
Krimm, I; Preto, J1
Mo, J; Wei, W; Xu, Y; Zhao, J; Zhu, L1
Chen, J; Cheng, W; Fang, B; Gan, B; Koppula, P; Lee, H; Lei, G; Liu, X; Mao, C; Nie, L; Qian, SB; Swanda, RV; Wang, C; Xiao, Z; Zhang, J; Zhang, Y; Zhuang, L1
Asantewaa, G; Harris, IS1
Fackelman, D; Fernando, V; Furuta, S; Letson, J; Sharma, V; Walia, Y; Zheng, X1
Moazampour, M; Shekari, Z; Zare, HR1
Jiang, WL; Li, CY; Li, Y; Mao, GJ; She, ZP; Wang, WX; Wang, ZQ1
Jin, M; Wang, J; You, J; Zhang, J1
Albone, EF; Butler, J; Cheng, X; Grasso, L; Jacob, S; Kline, JB; Milinichik, AZ; Park, YC; Spidel, JL; Vaessen, B1
Cesson, V; Derré, L; Iwaszkiewicz, J; Kalejta, K; Lach, S; Michielin, O; Olive, D; Rodziewicz-Motowidło, S; Speiser, DE; Spodzieja, M; Zoete, V1
Conibear, E; Davis, NG; Lin, DTS1
Berglund, UW; Brautigam, L; Helleday, T; Kadamov, Y; Tsuber, V1
Basu, A; Bhattacharjee, A; Bhattacharya, S; Ghosh, P; Samanta, A1
Reinheckel, T1
Bahri, MA; Becker, G; Cinier, M; Dammicco, S; Desselle, A; Doumont, G; Egrise, D; Gorré, H; Goux, M; Lallemand, F; Leroi, N; Luxen, A; Plenevaux, A1
Bomba, HN; Gu, Z; Lu, Y; Yang, G1
Fonović, M; Turk, B; Vizovišek, M1
Jia, Z; Khanal, P; Yang, X1
Cooper, AJL; Fiehn, O; Folz, J; Hanson, AD; McCarty, DR; Moraga Amador, D; Niehaus, TD1
Altai, M; Andersson, KG; Garousi, J; Löfblom, J; Mitran, B; Orlova, A; Oroujeni, M; Steinhardt, X; Tolmachev, V; Vorobyeva, A1
Babbar, A; Chen, Y; Feng, J; Hansen, R; Janes, MR; Li, LS; Liu, Y; Peters, U; Ren, P; Zarrinkar, PP1
Chen, X; Lei, X; Song, T; Wang, C; Ye, Z; Zhang, X; Zhu, Y1
Buecheler, JW; Gieseler, H; Tonillo, J; Weber, C; Winzer, M1
Bartoszewski, R; Pogorzelska, A; Żołnowska, B1
Bansal, A; Simon, MC1
Alshehri, S; Fan, W; Garrison, JC; Zhang, W1
Chen, W; Fang, T; Huang, G; Li, G; Liu, Y; Sheng, Y; Su, J; Tang, Q; Yuan, S; Zang, J; Zhang, X1
Abe, Y; Caaveiro, JMM; Fuchida, H; Hamachi, I; Hatsuyama, Y; Koyanagi, S; Kuwata, K; Matsunaga, N; Miura, C; Morimoto, S; Nakao, T; Ohdo, S; Ojida, A; Okamoto, K; Ono, M; Sakamoto, S; Sato, M; Shibata, T; Shindo, N; Shiroishi, M; Tamura, T; Tokunaga, K; Ueda, T; Watari, K; Yamaguchi, Y1
Lv, Y; So, KF; Wong, NK; Xiao, J1
Gao, M; Gao, P; Li, W; Lu, X; Mu, Y; Wang, Q; Wang, Y; Xu, G; Zhao, Y; Zhou, L; Zhou, Y1
Byeon, JH; Hwang, J; Kim, JO; Ku, SK; Poudel, BK1
Chan, TA; Chinnaiyan, A; Choi, JE; Cieslik, M; Georgiou, G; Gijón, M; Green, M; Gu, W; Johnson, JK; Kennedy, PD; Kryczek, I; Lamb, C; Lang, X; Lawrence, TS; Li, G; Li, J; Li, W; Liao, P; Liu, R; Sell, A; Stone, E; Szeliga, W; Tanno, Y; Vatan, L; Wang, W; Wei, S; Xia, H; Zhang, H; Zhou, J; Zou, W1
Ao, X; Ding, W; Ji, X; Liu, Y; Wang, J; Xu, T; Yu, W1
Cai, A; Chen, R; Chen, Z; Ganapathy, V; Kou, L; Sun, R; Xiao, S; Yao, Q; Zheng, H; Zheng, Y1
Cochran, JR; Leung, CL; Moore, SJ; Norton, HK1
Han, L; Tang, C; Yin, C1
Nagai, Y; Takao, M; Torii, T1
Chen, SQ; Lai, J; Pan, LQ; Wang, HB; Xu, YC; Zhang, C1
Bouziotis, P; Fani, M; Gourni, E; Livaniou, E; Loudos, G; Papadopoulos, M; Paravatou-Petsotas, M; Patsis, G; Pirmettis, I; Psimadas, D; Varvarigou, AD; Xanthopoulos, S; Zikos, C1
Chai, Y; Gui, G; Liao, N; Xiao, K; Yuan, R; Zhuo, Y1
Lee, YH; Seo, M1
Braun, GB; Kotamraju, VR; Pang, HB; Ruoslahti, E; She, ZG; Sugahara, KN; Teesalu, T1
Song, P; Zou, MH1
Cheng, Z; Chin, FT; Gambhir, SS; Jiang, L; Kimura, RH; Ma, X; Miao, Z; Shen, B; Shi, H; Tu, Y1
Majewski, M1
Aggarwal, BB; Gupta, SC; Han, JG; Prasad, S1
Alcutt, S; Artigues, A; Cooper, AJ; Dorai, T; Jones, ME; Krasnikov, BF; Li, J; Pinto, JT; Villar, MT1
Hishiki, T; Kabe, Y; Kubo, A; Nakanishi, T; Ohmura, M; Saya, H; Suematsu, M; Tamada, M; Toue, S; Tsuchihashi, K; Yamamoto, T1
Cao, R; Chen, S; Dian, L; Dong, T; He, S; Huang, N; Lei, X; Li, C; Li, L; Wang, X; Zhang, X1
Farhadyar, N; Karamipour, Sh; Sadjadi, MS1
Catling, SJ; Russell, IT; Thornton, CA1
Cativiela, C; Gimeno, MC; Gutiérrez, A; Laguna, A; Marzo, I1
Bertrand, N; Choi, WI; Farokhzad, OC; MacLean, JL; Mulvale, M; Shah, V; Shi, J; Wu, J; Xu, X; Yameen, B; Zhao, L1
Burden, RE; Gilmore, BF; Hughes, CS; Scott, CJ1
Han, J; Kim, JH; Kim, JS; Lee, YH; Lim, JY; Ren, WX; Sunwoo, K1
Butland, SL; Calzolari, D; Hayden, MR; Kay, C; Lavallée-Adam, M; Martin, DD; Sanders, SS; Yates, JR1
Ha, KS; Jeon, HY; Jung, SH; Kim, WJ; Kim, YM; Kong, DH1
Campbell, SL; Huynh, MV1
Bazalova-Carter, M; Brewer, KD; Dane Wittrup, K; Graves, EE; Kempen, P; Lee, KH; Rao, J; Rutt, B; Shuhendler, AJ; Ye, D1
Arkin, MR; Dansen, TB; Visscher, M1
Andre, FR; dos Santos, PF; Rando, DG1
Clarke, DJ; Faktor, J; Hupp, TR; MacKay, CL; Mohtar, A; Murray, E; Smith, PL; Vojtesek, B1
Bian, K; Keidar, M; Murad, F; Nourmohammadi, N; Sherman, JH; Yan, D1
Kanoh, D; Kikuchi, S; Nakamura, H; Sakurai, Y; Sato, S; Suzuki, M1
Anta, B; Castro, J; Crespo, P; Durá, LM; García-Domínguez, CA; Gragera, T; Hernández, S; Ibiza, S; Martínez, N; Muñoz, A; Oliva, JL; Peña-Jiménez, D; Pérez-Rodríguez, A; Rojas-Cabañeros, JM; Santos, E; Serrador, JM; Yunta, M; Zarich, N1
Abegg, D; Adibekian, A; Hoch, DG; Lagoutte, R; Serba, C; Winssinger, N1
Funato, Y; Gehring, K; Gulerez, I; Kozlov, G; Miki, H; Wu, H; Yang, M1
Alonso, LG; Borkosky, SS; Camporeale, G; de Prat Gay, G; Lorenzo, JR; Risso, MG; Salvatierra, E; Sánchez, IE; Thomas, MG1
Gangapurkar, B; Jariwalla, RJ; Nakamura, D1
Caragacianu, D; Downey, S; El-Gamil, M; Hong, JA; Li, Y; Morgan, RA; Robbins, PF; Rosenberg, SA; Schrump, DS; Wargo, JA; Zhao, Y; Zheng, Z1
Klemke, M; Samstag, Y1
Aimiuwu, J; Bhasin, D; Chan, KK; Chen, P; Fuchs, JR; Huang, TH; Li, C; Li, PK; Liu, S; Liu, Z; Marcucci, G; Neviani, P; Pang, J; Pavlovicz, RE; Perrotti, D; Plass, C; Rush, L; Wang, H; Wu, J; Wu, LC; Xie, Z1
Chester, KA; Constantinou, A; Deonarain, MP; Epenetos, AA; Hreczuk-Hirst, D; Jain, S; Wright, M1
Beuttler, J; Frejd, FY; Kontermann, RE; Müller, D; Rothdiener, M1
Liang, PH; Lin, YF; Liu, HG; Tsai, WP1
Bowers, RR; He, L; Hutchens, S; Manevich, Y; Tew, KD; Townsend, DM; Xiong, Y1
Feng, J; Lu, D; Qiu, Y; Yan, X; Yang, D; Zeng, Q; Zhang, Y; Zheng, C1
Echigo, S; Endo, M; Rikiishi, H; Shinohara, F; Suzuki, M1
Abassi, Y; An, H; Fan, W; Feinstein, SC; Gaylord, M; Geng, B; Sui, M; Wang, X; Wu, J; Xi, B; Xu, W; Xu, X; Yan, H; Zhu, J1
Cheng, WH; Kang, MM; Schoene, NW; Wu, M1
CLOWES, GH; HARRIS, PN; KRAHL, ME1
Dastidar, S; Gupta, S; Ray, A; Singh, RK1
Baretton, GB; Baumann, M; Calleja, V; Cordes, N; Eke, I; Fässler, R; Haase, M; Hehlgans, S; Koch, U; Larijani, B; Pilarsky, C; Sandfort, V; Shevchenko, A; Stanchi, F; Zips, D1
Bhat, GJ; Chuang, T; Srivenugopal, KS; Yusuf, MA1
Aggarwal, BB; Chaturvedi, MM; Gupta, SC; Hema, PS; Kannappan, R; Nair, M; Prasad, S; Ravindran, J; Reuter, S; Yadav, VR1
Adam, V; Huska, D; Kizek, R; Krizkova, S; Kukacka, J; Masarik, M; Prusa, R; Zitka, O1
Chuttani, K; Kakkar, D; Kaul, A; Mishra, AK; Singh, H; Tiwari, AK1
Deng, H; Meng, Q; Shi, X; Tang, G; Tang, X; Wang, H; Wen, F; Wu, K; Yi, C1
Aitken, JB; de Jonge, MD; Finney, LA; Harris, HH; Howard, DL; Musgrave, IF; Paterson, DJ; Vogt, S; Weekley, CM1
Du, J; King, I; Nassar, AE1
Apeland, T; Bates, CJ; Drabløs, PA; Hervig, T; Mansoor, MA; Stakkestad, JA; Wentzel-Larsen, T1
Liu, X; Pietsch, KE; Sturla, SJ1
Bhattacharya, A1
Bernhard, EJ1
Bianchi, G; Borgonovo, G; Pistoia, V; Raffaghello, L1
Furrer, J; Giannini, F; Süss-Fink, G1
Chantranupong, L; Georgiou, G; Gonzalez, C; O'Neal, J; Rani, M; Stone, E; VanDenBerg, C1
Aranda, E; De La Haba-Rodriguez, JR; López-Pedrera, C; Rodriguez-Ariza, A1
Blum, G; Bogyo, M; Cheng, Z; Edgington, LE; Gambhir, SS; Gheysens, O; Jiang, H; Liu, H; Miao, Z; Ren, G; Syed, S; Verdoes, M1
Ahmad, R; Alam, M; Kosugi, M; Kufe, D; Uchida, Y1
Ahmad, R; Kharbanda, S; Kufe, D; Panchamoorthy, G; Raina, D; Rajabi, H1
Lyon, RP; Meyer, DL; Senter, PD; Setter, JR1
Antoch, MP; Chernov, MV; Comas-Soberats, M; Fedtsova, N; Gleiberman, AS; Gudkov, AV; Hu, Y; Jackson, M; Kuropatwinski, KK; Rustum, YM; Spengler, ML1
Jammaz, IA; Okarvi, SM1
Beijnen, JH; Darwish, M; Dubbelman, AC; Hellriegel, E; Jansen, RS; Robertson, P; Rosing, H; Schellens, JH1
Blanco, MD; Iglesias, I; Martínez, A; Muñiz, E; Teijón, JM1
Altschmied, J; Haendeler, J; Matsushima, S; Sadoshima, J; Shao, D; Zschauer, TC1
Carotti, A; Catto, M; Indiveri, C; Introcaso, A; Koutentis, PA; Koyioni, M; Michaelidou, SS; Nicolotti, O; Oppedisano, F; Pochini, L1
Cheng, JX; Kim, S; Lee, SY; Park, K; Tyler, JY1
Longtin, R1
Chorostowska-Wynimko, J; Jankun, J; Selman, SH; Skrzypczak-Jankun, E; Swiercz, R; Wojtowicz, A1
Irie, K; Masuda, A; Miyasaka, K; Ohigashi, H; Saito, N; Shindo, M; Shirai, Y1
Hausheer, F; Murphy, M; Pendyala, L; Schwartz, G; Smith, P; Zdanowicz, J1
Ayral-Kaloustian, S; Salaski, EJ1
HALL, V1
GAVOSTO, F; PAOLINO, W1
GIAMPAOLO, R; ROMANO, M; RUFFO, A1
SUHRLAND, LG; WEISBERGER, AS1
ALLARD, C; CANTE RO, A; DE LAMIRANDE, G1
ROBERTS, JJ; WARWICK, GP2
MENKE, KH; NEGELEIN, E; SCHOEN, R1
SUGAR, EA1
HARUNA, H; HASHIMOTO, S; IZUMI, K; KATAYAMA, M; MATSUBAYASHI, Y; OGISO, A; OKUJIMA, J; SUZUKI, S; TAKANO, T1
MORSE, BS; NUSSBAUM, M1
CHEN, JT; CHOU, CH; HSU, B; SHEN, ML1
HO, S1
CHASOVSKIKH, GG; GRIGOREV, IuA; MELESHIN, SV; MIKHAILOVA, LP; SHURIN, SP1
CAIN, DF; CHAMBERS, J; PRIER, JE1
MUELLER, OH1
CRADDOCK, VM1
FISHER, JM; RABINOVITZ, M1
Booker, BM; Creaven, P; Pendyala, L; Perez, R; Smith, PF1
Tapiero, H; Tew, KD; Townsend, DM1
Cheung, CW; Gambhir, SS; Li, L; Olafsen, T; Raubitschek, AA; Sherman, MA; Shively, JE; Sundaresan, G; Williams, LE; Wu, AM; Yazaki, PJ1
Cao, S; Durrani, FA; Rustum, YM1
Correia, I; Evangelou, AM; Kabanos, T; Kalfakakou, V; Karkabounas, S; Liasko, R; Manos, M; Papaioannou, A; Pessoa, JC1
Antony, AC; Guo, L; Jayaram, HN; Roeske, RW; Zhang, Y1
Chae, HZ; Chae, SK; Chung, MS; Hwang, CY; Kim, KD; Kwon, KS; Park, SS; Ryu, YS1
Gius, D1
Hanahan, D; Joyce, JA1
Imam, SK1
Bukowska, B1
Berdowska, I; Siewiński, M1
Cao, S; Durrani, FA; Fakih, M; Rustum, YM1
Chen, C; Cheng, X; Dong, JT; Dong, XY; Guo, P; Ling, J; Lingrel, JB; Sethi, P; Simons, JW; Sun, X; Zhou, J1
Abdulah, R; Koyama, H; Miyazaki, K; Nakazawa, M1
Dewey, VC; Kidder, GW1
Na, HK; Surh, YJ1
Cheung, HW; Chu, Q; Feng, H; Ling, MT; Tsao, SW; Wang, X; Wong, YC1
Deisenroth, C; Jin, A; Lindström, MS; White Wolf, G; Zhang, Y1
Giles, GI1
Chaudhuri, AR; De Waal, E; Goins, BA; Grubbs, B; Herman, B; Ikeno, Y; Mundy, GR; Padalecki, SS; Richardson, A; Zhang, Y1
Azrak, RG; Cao, S; Combs, GF; Durrani, FA; Fakih, M; Pendyala, L; Prey, J; Rustum, YM; Smith, PF1
Denz, HA; Fiegl, M; Frick, B; Fuchs, D; Schroecksnadel, K; Winkler, C1
Giovannini, C; Grande, S; Guidoni, L; Luciani, AM; Palma, A; Rosi, A; Sapora, O; Viti, V1
Decristoforo, C; Dietrich, H; Gabriel, M; Skvortsova, I; Virgolini, IJ; von Guggenberg, E1
Hamajima, N; Hatooka, S; Hishida, A; Iwata, H; Kagami, Y; Kato, T; Matsuo, K; Mitsudomi, T; Naito, M; Ogura, M; Shinoda, M; Suyama, M; Tajima, K; Tamakoshi, A; Tanaka, D; Yamamoto, K; Yamamura, Y1
Herzon, SB; Myers, AG; Siegrist, R; Wulff, JE1
Dewhirst, MW; Huang, Q; Li, CY; Li, F; Liu, S; Rabbani, ZN; Sonveaux, P; Vujaskovic, Z; Yan, B1
Huber, WW; Parzefall, W1
Eichinger, A; Kim, HJ; Nasreen, A; Skerra, A1
Boos, J; Hempel, G; Koling, S; Lanvers, C; Würthwein, G1
Algar, U; Blokhuis, MM; Goldberg, PA; Govender, D; Pietersen, GE; Ramesar, RS; Vorster, AA1
Chen, RK; Chen, YY; Hsu, SF; Khoo, KH; Lee, CL; Lou, YW; Meng, TC; Tonks, NK1
Ahlgren, S; Baastrup, B; Fant, G; Feldwisch, J; Orlova, A; Rosik, D; Sandström, M; Sjöberg, A; Tolmachev, V; Widmark, O1
Clark, CJ; Sage, EH1
Balendiran, GK; Haq, W; Martin, HJ; Maser, E; O'Connor, TR; Verma, M1
Barbouti, A; Galaris, D; Skiada, V1
Lancaster, JR1
Chu, FC; Kim, JH1
Baker, LH; Evans, LJ; Haas, CD1
Howell, SB; Wung, WE1
Kumasaka, K; Sekiguchi, M1
Baker, LH; Evans, LJ; Hutchison, JS; Young, JD1
Adams, GP; Bookman, MA; Hudziak, RM; Jin, D; Laminet, AA; Liu, S; McCartney, JE; Oppermann, H; Tai, MS; Wolf, EJ1
Milner, JA; Sundaram, SG1
Besterman, JM; Chagwedera, TE; Chai, HB; Cordell, GA; Farnsworth, NR; Kinghorn, AD; Lee, IS; Pezzuto, JM; Shamon, LA1
Bockstette, M; Dröge, W; Galter, D; Gross, A; Hack, V; Kinscherf, R; Mihm, S; Schykowski, M1
Ali-Osman, F; Srivenugopal, KS1
Heber, D1
Bottiglieri, T; Farrow, A; Griener, JC; Hyland, K; Kamen, BA; Quinn, CT1
Dröge, W; Holm, E1
Gumińska, M; Ignacak, J; Kedryna, T; Stachurska, MB1
Hirai, M; Katoh, M; Koike, J; Miwa, T; Takagi, A; Terada, M1
Ganther, HE1
Bolanowska-Higdon, W; Creaven, PJ; Meropol, NJ; Murphy, M; Pendyala, L; Perez, R; Schwartz, G; Zdanowicz, J1
Clarke, DM; Loo, TW1
Baraldi, PG; Bianchi, N; Bolzati, C; Duatti, A; Gambari, R; Mischiati, C; Piffanelli, A; Romagnoli, R1
Marchenko, GN; Strongin, AY1
Holt, JA1
Horan, AD; Koch, CJ1
Akyuz, C; Caglar, M; Yarís, N1
Danenberg, PV1
Bahnemann, D; Basaga, H; Dunlop, JR; Searle, AJ; Willson, RL1
Searle, AJ; Willson, RL1
Matsumoto, H; Mori, S1
Anders, MW1
Morita, K; Ohta, T1
Amino, S; Hashimoto, S; Horiuchi, J; Mochizuki, Y; Mori, T; Morita, K; Ohkawa, T; Takekawa, Y; Tanaka, Y; Yanagisawa, T1
Ahern, JD; Balishin, NL; Defeo-Jones, D; Edwards, GM; FitzGerald, DJ; Heimbrook, DC; Oliff, A; Pastan, I; Patrick, DR; Stirdivant, SM1
Kinoshita, F; Maekawa, A; Oshima, T; Tsukiyama, I1
Dresden, MH; Heilman, SA; Schmidt, JD1
Homolka, J1
Huber, R; Teichmann, B1
Menkès, G1

Reviews

75 review(s) available for cysteine and Neoplasms

ArticleYear
[Cysteine cathepsins: structure, physiological functions and their role in carcinogenesis].
    Biomeditsinskaia khimiia, 2021, Volume: 67, Issue:6

    Topics: Carcinogenesis; Cathepsins; Cell Transformation, Neoplastic; Cysteine; Humans; Neoplasms

2021
Cysteinyl Leukotriene Pathway and Cancer.
    International journal of molecular sciences, 2021, Dec-23, Volume: 23, Issue:1

    Topics: Animals; Apoptosis; Cell Proliferation; Cysteine; Humans; Leukotrienes; Neoplasms; Retrospective Studies; Signal Transduction

2021
Transsulfuration, minor player or crucial for cysteine homeostasis in cancer.
    Trends in cell biology, 2022, Volume: 32, Issue:9

    Topics: Cysteine; Glutathione; Homeostasis; Humans; Neoplasms; Sulfur

2022
Ferroptosis and Cancer Immunotherapy.
    Current molecular medicine, 2023, Volume: 23, Issue:5

    Topics: Cysteine; Cytokines; Ferroptosis; Immunotherapy; Iron; Neoplasms

2023
Therapeutic Targeting the Allosteric Cysteinome of RAS and Kinase Families.
    Journal of molecular biology, 2022, 09-15, Volume: 434, Issue:17

    Topics: Antineoplastic Agents; Cysteine; Humans; Molecular Targeted Therapy; Neoplasms; Protein Kinase Inhibitors; Protein Kinases; ras Proteins

2022
Hydrogen Sulfide Biology and Its Role in Cancer.
    Molecules (Basel, Switzerland), 2022, May-25, Volume: 27, Issue:11

    Topics: Animals; Biology; Cysteine; Hydrogen Sulfide; Mammals; Neoplasms; Signal Transduction

2022
Muscle-to-tumor crosstalk: The effect of exercise-induced myokine on cancer progression.
    Biochimica et biophysica acta. Reviews on cancer, 2022, Volume: 1877, Issue:5

    Topics: Brain-Derived Neurotrophic Factor; Cachexia; Cysteine; Fibronectins; Glucose; Humans; Inflammation; Interleukin-15; Interleukin-6; Interleukin-8; Muscle, Skeletal; Myostatin; Neoplasms; Oncostatin M; Osteonectin; Tumor Microenvironment

2022
Cysteine Metabolism in Tumor Redox Homeostasis.
    Current medicinal chemistry, 2023, Volume: 30, Issue:16

    Topics: Cysteine; Glutathione; Homeostasis; Humans; Hydrogen Sulfide; Neoplasms; Oxidation-Reduction; Quality of Life

2023
Cysteine Cathepsins in Breast Cancer: Promising Targets for Fluorescence-Guided Surgery.
    Molecular imaging and biology, 2023, Volume: 25, Issue:1

    Topics: Animals; Breast Neoplasms; Cathepsins; Cysteine; Fluorescence; Fluorescent Dyes; Humans; Mice; Neoplasms

2023
NO news: S-(de)nitrosylation of cathepsins and their relationship with cancer.
    Analytical biochemistry, 2022, 10-15, Volume: 655

    Topics: Cathepsins; Cysteine; Humans; Neoplasms; Nitric Oxide; Oxidation-Reduction

2022
Essential Roles of Peroxiredoxin IV in Inflammation and Cancer.
    Molecules (Basel, Switzerland), 2022, Oct-02, Volume: 27, Issue:19

    Topics: Cysteine; Humans; Hydrogen Peroxide; Inflammation; Neoplasms; Peroxiredoxins

2022
Targeting amino acid metabolism in cancer.
    International review of cell and molecular biology, 2022, Volume: 373

    Topics: Amino Acids; Arginine; Asparagine; Cysteine; Humans; Methionine; Neoplasms

2022
Drugging KRAS: current perspectives and state-of-art review.
    Journal of hematology & oncology, 2022, 10-25, Volume: 15, Issue:1

    Topics: Antineoplastic Agents; Cysteine; Guanosine Triphosphate; Humans; Immune Checkpoint Inhibitors; Mutation; Neoplasms; Proto-Oncogene Proteins p21(ras); Tumor Microenvironment

2022
Discovery of cysteine-targeting covalent histone methyltransferase inhibitors.
    European journal of medicinal chemistry, 2023, Jan-15, Volume: 246

    Topics: Cysteine; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Neoplasms

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosphate; Adsorption; Adult; Africa, Eastern; Aged; Air Pollutants; Air Pollution; Air Pollution, Indoor; Alcohol Drinking; Allergens; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Anti-Bacterial Agents; Antibodies; Antibodies, Immobilized; Antigen Presentation; Antigens, CD; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Aptamers, Nucleotide; Asthma; Asthma, Exercise-Induced; Atrophy; Autophagy; Azoospermia; Bacillus cereus; Bacterial Infections; Beclin-1; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Biofouling; Biological Monitoring; Biomarkers; Biomarkers, Tumor; Biosensing Techniques; Blastocyst; Bone Neoplasms; Bone Regeneration; Bronchoconstriction; Burkitt Lymphoma; C9orf72 Protein; Campylobacter; Campylobacter Infections; Campylobacter jejuni; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Cardiomyopathies; Caregivers; Carmine; Case-Control Studies; Catalysis; Cattle; Cause of Death; CCAAT-Enhancer-Binding Protein-alpha; CD8-Positive T-Lymphocytes; Cefepime; Cell Differentiation; Cell Line, Tumor; Cell Nucleus; Cell Transdifferentiation; Chelating Agents; Chemical and Drug Induced Liver Injury, Chronic; Chemoradiotherapy, Adjuvant; Child; Child, Preschool; China; Chlorquinaldol; Cholangiocarcinoma; Cholera; Chromatin; Clinical Trials as Topic; Cognitive Dysfunction; Cohort Studies; Colonic Neoplasms; Colorectal Neoplasms; Colorimetry; Cooking; Coordination Complexes; COVID-19; Creatinine; CRISPR-Cas Systems; Critical Care; Critical Illness; Cross-Sectional Studies; Cryopreservation; Cryoprotective Agents; Cysteine; Cytokines; Device Removal; Diet; Diet, High-Fat; Diet, Mediterranean; Dietary Supplements; Dimethyl Sulfoxide; Dipeptides; Disease Models, Animal; Dithiothreitol; DNA; DNA Repeat Expansion; DNA, Bacterial; DNA, Complementary; Dopamine; Electrochemical Techniques; Electrodes; Endocannabinoids; Environmental Exposure; Environmental Monitoring; Environmental Pollutants; Enzyme-Linked Immunosorbent Assay; Erlotinib Hydrochloride; Escherichia coli; Escherichia coli O157; Esophageal Neoplasms; Esophagitis, Peptic; Ethylene Glycol; Europium; Exanthema; Fallopian Tubes; Feces; Female; Fertilization in Vitro; Fluoresceins; Fluorescent Dyes; Follicle Stimulating Hormone; Follow-Up Studies; Food Microbiology; Forced Expiratory Volume; Forkhead Transcription Factors; Frontotemporal Dementia; G-Quadruplexes; Galactose; Gastroenteritis; Gastrointestinal Diseases; Gastrointestinal Microbiome; Gastrointestinal Neoplasms; Gastrointestinal Tract; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genital Neoplasms, Female; Genome-Wide Association Study; Genome, Viral; Genomics; Genotype; Glucose; Glutathione; Glycerol; Gold; Graphite; GTPase-Activating Proteins; Heat-Shock Proteins; Heme Oxygenase-1; Hepacivirus; Hepatitis C; Hepatocytes; Histamine; Histocompatibility Antigens Class II; Hoarseness; Hospice and Palliative Care Nursing; Humans; Hydrogen; Hydrogen Peroxide; Hydrogen Sulfide; Hydroxybenzoates; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperthermia, Induced; Hysteroscopy; Immunoassay; Indigo Carmine; Inflammation; Inflammatory Bowel Diseases; Insulin Resistance; Intensive Care Units; Interleukin-11; Interleukin-6; Interleukins; Iodine Radioisotopes; Iran; Iridium; Islets of Langerhans; Kinetics; Lactation; Lactobacillus; Lactobacillus plantarum; Lamins; Latin America; Lead; Lectins; Leukopenia; Ligands; Limit of Detection; Lipopolysaccharides; Lipoprotein Lipase; Liver; Liver Cirrhosis; Liver Neoplasms; Lolium; Luminescent Measurements; Luminol; Lung; Luteinizing Hormone; Macrophages; Magnetic Phenomena; Magnetic Resonance Imaging; Male; Malnutrition; Maltose; Manganese Compounds; Maternal Nutritional Physiological Phenomena; Melatonin; Metabolic Engineering; Metal Nanoparticles; Metallocenes; Metaplasia; Methicillin-Resistant Staphylococcus aureus; Methylation; Mevalonic Acid; Mexico; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microbial Sensitivity Tests; Microbiota; MicroRNAs; Milk; Mitomycin; Molecular Diagnostic Techniques; Molecular Docking Simulation; Monte Carlo Method; Moringa oleifera; Multiple Sclerosis; Muscle Strength; Muscle, Skeletal; Nanocomposites; Nanotubes, Carbon; Neoadjuvant Therapy; Neoplasms; Neurodegenerative Diseases; Neurotransmitter Agents; NF-E2-Related Factor 2; Nickel; Nitrogen Dioxide; Non-alcoholic Fatty Liver Disease; Nucleic Acid Amplification Techniques; Nucleic Acid Hybridization; Nucleocapsid Proteins; Nutritional Status; Obesity; Osteogenesis; Osteosarcoma; Oxidation-Reduction; Oxides; Oxygen; Oxyquinoline; Pain; Palliative Care; Pancreatic Neoplasms; Pandemics; Particulate Matter; Peroxidase; Peroxidases; Phagocytosis; Phaseolus; Photothermal Therapy; Point-of-Care Systems; Polyethyleneimine; Polymers; Polymorphism, Single Nucleotide; Polysomnography; Postoperative Complications; Pregnancy; Pregnant Women; Prenatal Exposure Delayed Effects; Prevalence; Printing, Three-Dimensional; Probability; Probiotics; Prognosis; Prophages; Prospective Studies; Proteomics; Proto-Oncogene Proteins; Pseudomonas aeruginosa; Pseudomonas putida; Pulmonary Disease, Chronic Obstructive; Pulmonary Embolism; Pyridines; Pyrroles; Quality of Life; Quinolones; Rabbits; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Receptors, Histamine; Receptors, Histamine H2; Recombinases; Rectal Neoplasms; Reperfusion Injury; Respiration; Respiratory Function Tests; Respiratory Rate; Respiratory Sounds; Retrospective Studies; rho GTP-Binding Proteins; Risk Assessment; Risk Factors; RNA; RNA, Messenger; RNA, Ribosomal, 16S; Robotic Surgical Procedures; Running; Rural Population; Saccharomyces cerevisiae; Salpingectomy; Sarcopenia; SARS-CoV-2; Seeds; Semen; Sensitivity and Specificity; Sepsis; Shock, Septic; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Skin Neoplasms; Sleep Apnea, Obstructive; Soil; Spain; Spectrum Analysis, Raman; Sperm Retrieval; Spermatozoa; Spirometry; Staphylococcus aureus; STAT3 Transcription Factor; Stereoisomerism; Sterilization, Tubal; Stroke Volume; Sulfadiazine; Sulfites; Superoxide Dismutase; Surface Plasmon Resonance; tau Proteins; Testis; Testosterone; Thioredoxin-Disulfide Reductase; Thyroid Neoplasms; Thyroidectomy; Trans-Activators; Transcription Factor AP-1; Treatment Outcome; Triazoles; Triclosan; Trifluridine; Tumor Microenvironment; Tumor Necrosis Factor-alpha; United States; Uracil; Vagina; Vegetables; Ventricular Function, Left; Ventricular Pressure; Vibrio cholerae; Vietnam; Virulence; Vital Capacity; Vitrification; Walking; Water; Water Pollutants, Radioactive; Whole Genome Sequencing; Wind; YAP-Signaling Proteins; Zeolites; Zinc Oxide

2023
Diverse Roles of Protein Palmitoylation in Cancer Progression, Immunity, Stemness, and Beyond.
    Cells, 2023, 09-05, Volume: 12, Issue:18

    Topics: Cysteine; Humans; Lipoylation; Neoplasms; Neoplastic Processes; Neoplastic Stem Cells

2023
The Role of Cysteine Protease Cathepsins B, H, C, and X/Z in Neurodegenerative Diseases and Cancer.
    International journal of molecular sciences, 2023, Oct-26, Volume: 24, Issue:21

    Topics: Cathepsin B; Cysteine; Cysteine Proteases; Humans; Lysosomes; Neoplasms; Neurodegenerative Diseases

2023
Sulfur metabolism and its contribution to malignancy.
    International review of cell and molecular biology, 2019, Volume: 347

    Topics: Animals; Carcinogenesis; Chelating Agents; Cysteine; Humans; Metallothionein; Methionine; Mitogen-Activated Protein Kinase Kinases; Neoplasms; Oxidation-Reduction; Oxidative Stress; Sulfhydryl Compounds; Sulfur

2019
Cysteine Cathepsins: Potential Applications in Diagnostics and Therapy of Malignant Tumors.
    Biochemistry. Biokhimiia, 2019, Volume: 84, Issue:7

    Topics: Animals; Biomarkers, Tumor; Carcinogenesis; Cathepsins; Cysteine; Drug Resistance, Neoplasm; Extracellular Matrix; Fluorescence Resonance Energy Transfer; Humans; Immunoconjugates; Mice; Molecular Targeted Therapy; Nanoparticles; Neoplasms; Proteolysis; Tumor Microenvironment

2019
Recent Advances in Bioorthogonal Click Chemistry for Efficient Synthesis of Radiotracers and Radiopharmaceuticals.
    Molecules (Basel, Switzerland), 2019, Oct-02, Volume: 24, Issue:19

    Topics: Animals; Antineoplastic Agents; Catalysis; Click Chemistry; Cycloaddition Reaction; Cysteine; Humans; Molecular Imaging; Molecular Structure; Neoplasms; Radiopharmaceuticals

2019
Garlic-derived bioactive compound S-allylcysteine inhibits cancer progression through diverse molecular mechanisms.
    Nutrition research (New York, N.Y.), 2020, Volume: 73

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Proliferation; Cysteine; Disease Models, Animal; Garlic; Humans; Mice; Neoplasms; Rats

2020
Therapeutic targeting of protein S-acylation for the treatment of disease.
    Biochemical Society transactions, 2020, 02-28, Volume: 48, Issue:1

    Topics: Acyltransferases; Animals; B7-H1 Antigen; Cysteine; Drug Discovery; Humans; Lipoylation; Mice; Neoplasms; Palmitoyl-CoA Hydrolase; Protein Processing, Post-Translational; ras Proteins; Receptor, Melanocortin, Type 1

2020
Reductive Stress, Bioactive Compounds, Redox-Active Metals, and Dormant Tumor Cell Biology to Develop Redox-Based Tools for the Treatment of Cancer.
    Antioxidants & redox signaling, 2020, 10-20, Volume: 33, Issue:12

    Topics: Animals; Biological Products; Cysteine; Glutathione; Homeostasis; Humans; Metals; Mitochondria; Neoplasm Metastasis; Neoplasm Staging; Neoplasms; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species

2020
Tumor cell- and microenvironment-specific roles of cysteine cathepsins in mouse models of human cancers.
    Biochimica et biophysica acta. Proteins and proteomics, 2020, Volume: 1868, Issue:7

    Topics: Allografts; Animals; Breast Neoplasms; Carcinogenesis; Cathepsin B; Cathepsin L; Cathepsins; Cysteine; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Humans; Intestinal Neoplasms; Mice; Neoplasms; Pancreatic Neoplasms; Skin Neoplasms; Tumor Microenvironment

2020
Prevailing Knowledge on the Bioavailability and Biological Activities of Sulphur Compounds from Alliums: A Potential Drug Candidate.
    Molecules (Basel, Switzerland), 2020, Sep-09, Volume: 25, Issue:18

    Topics: Allium; Animals; Anti-Infective Agents; Antineoplastic Agents; Blood Platelets; Cysteine; Disulfides; Fibrinolysis; Garlic; Humans; Immunologic Factors; Neoplasms; Obesity; Phytochemicals; Plant Extracts; Solubility; Sulfoxides; Sulfur; Sulfur Compounds

2020
The Relationship Between Protein S-Nitrosylation and Human Diseases: A Review.
    Neurochemical research, 2020, Volume: 45, Issue:12

    Topics: Animals; Brain Diseases; Cardiovascular Diseases; Cysteine; Humans; Neoplasms; Nitric Oxide; Protein Processing, Post-Translational; Proteins; S-Nitrosothiols

2020
Cysteine metabolic circuitries: druggable targets in cancer.
    British journal of cancer, 2021, Volume: 124, Issue:5

    Topics: Animals; Cysteine; Energy Metabolism; Epigenesis, Genetic; Glycolysis; Humans; Hydrogen Sulfide; Metabolic Networks and Pathways; Mitochondria; Molecular Targeted Therapy; Neoplasms

2021
Discoveries in the redox regulation of KRAS.
    The international journal of biochemistry & cell biology, 2021, Volume: 131

    Topics: Animals; Antineoplastic Agents; Cysteine; Gene Expression Regulation, Neoplastic; Humans; Hydrogen Peroxide; Mutation; Neoplasms; Nitrosation; Oxidation-Reduction; Piperazines; Protease Inhibitors; Protein Processing, Post-Translational; Proto-Oncogene Proteins p21(ras); Pyridines; Pyrimidines; Signal Transduction; Sulfinic Acids

2021
Cellular S-denitrosylases: Potential role and interplay of Thioredoxin, TRP14, and Glutaredoxin systems in thiol-dependent protein denitrosylation.
    The international journal of biochemistry & cell biology, 2021, Volume: 131

    Topics: Cardiovascular Diseases; Cysteine; Gene Expression Regulation; Glutaredoxins; Humans; Immune System Diseases; Neoplasms; Neurodegenerative Diseases; Nitric Oxide; Nitrosation; Nitrosative Stress; Oxidation-Reduction; S-Nitrosothiols; Signal Transduction; Substrate Specificity; Thioredoxins

2021
Emerging role of cysteinyl LTs in cancer.
    British journal of pharmacology, 2022, Volume: 179, Issue:22

    Topics: Carcinogenesis; Cysteine; Humans; Leukotrienes; Neoplasms; Tumor Microenvironment

2022
Ferroptosis: mechanisms and links with diseases.
    Signal transduction and targeted therapy, 2021, 02-03, Volume: 6, Issue:1

    Topics: Alzheimer Disease; Apoptosis; Autophagy; Cysteine; Ferroptosis; Humans; Iron; Lipid Metabolism; Lipid Peroxidation; Neoplasms; Parkinson Disease; Reactive Oxygen Species

2021
Glutathione and its precursors in cancer.
    Current opinion in biotechnology, 2021, Volume: 68

    Topics: Cysteine; Glutathione; Humans; Neoplasms; Oxidative Stress; Reactive Oxygen Species

2021
S-Nitrosylation in Tumor Microenvironment.
    International journal of molecular sciences, 2021, Apr-27, Volume: 22, Issue:9

    Topics: Animals; Biochemical Phenomena; Cysteine; Humans; Neoplasms; Nitric Oxide; Protein Interaction Mapping; Protein Processing, Post-Translational; Proteins; Signal Transduction; Sulfhydryl Compounds; Tumor Microenvironment

2021
Cysteine-Based Coupling: Challenges and Solutions.
    Bioconjugate chemistry, 2021, 08-18, Volume: 32, Issue:8

    Topics: Animals; Antineoplastic Agents, Immunological; Chemistry Techniques, Synthetic; Cysteine; Humans; Immunoconjugates; Neoplasms

2021
Targeting the Ras palmitoylation/depalmitoylation cycle in cancer.
    Biochemical Society transactions, 2017, 08-15, Volume: 45, Issue:4

    Topics: Acyltransferases; Animals; Antineoplastic Agents; Carcinogenesis; Cysteine; Enzyme Activation; Enzyme Inhibitors; Humans; Hydrolysis; Isoenzymes; Lipoylation; Molecular Targeted Therapy; Mutation; Neoplasm Proteins; Neoplasms; Protein Processing, Post-Translational; Protein Transport; ras Proteins; Thiolester Hydrolases

2017
Cysteine-rich Proteins for Drug Delivery and Diagnosis.
    Current medicinal chemistry, 2019, Volume: 26, Issue:8

    Topics: Animals; Biocompatible Materials; Cysteine; Drug Carriers; Drug Delivery Systems; Gold; Humans; Hydrogels; Nanocomposites; Nanoparticles; Nanotechnology; Neoplasms; Proteins

2019
Cysteine cathepsins in extracellular matrix remodeling: Extracellular matrix degradation and beyond.
    Matrix biology : journal of the International Society for Matrix Biology, 2019, Volume: 75-76

    Topics: Arthritis, Rheumatoid; Cathepsins; Cysteine; Cysteine Endopeptidases; Extracellular Matrix; Heart Diseases; Humans; Inflammation; Lysosomes; Neoplasms; Proteolysis

2019
Cysteine cathepsins as a prospective target for anticancer therapies-current progress and prospects.
    Biochimie, 2018, Volume: 151

    Topics: Animals; Antineoplastic Agents; Cathepsins; Cysteine; Humans; Neoplasms

2018
Glutathione metabolism in cancer progression and treatment resistance.
    The Journal of cell biology, 2018, 07-02, Volume: 217, Issue:7

    Topics: Antioxidants; Cysteine; Drug Resistance, Neoplasm; Glutathione; Homeostasis; Humans; Neoplasms; Signal Transduction; Xenobiotics

2018
Anti-cancer activities of S-allylmercaptocysteine from aged garlic.
    Chinese journal of natural medicines, 2019, Volume: 17, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cysteine; Disease Models, Animal; Garlic; Humans; Molecular Structure; Neoplasms; Signal Transduction

2019
Molecular mechanisms of ferroptosis and its role in cancer therapy.
    Journal of cellular and molecular medicine, 2019, Volume: 23, Issue:8

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cysteine; Endoplasmic Reticulum Stress; Fatty Acids, Unsaturated; Ferroptosis; Glutamine; Humans; Iron; Lipid Peroxidation; Lysosomes; Mitochondria; Neoplasms; Phospholipid Hydroperoxide Glutathione Peroxidase; Signal Transduction

2019
Allium sativum: facts and myths regarding human health.
    Roczniki Panstwowego Zakladu Higieny, 2014, Volume: 65, Issue:1

    Topics: Antioxidants; Carbon-Sulfur Lyases; Cardiovascular Diseases; Cysteine; Disulfides; Garlic; Humans; Hypercholesterolemia; Neoplasms; Phytotherapy; Plant Extracts; Protective Agents; Sulfinic Acids

2014
Strategies for detection and quantification of cysteine cathepsins-evolution from bench to bedside.
    Biochimie, 2016, Volume: 122

    Topics: Animals; Cathepsins; Cysteine; Enzyme Assays; Humans; Neoplasms; Protein Binding; Proteomics; Substrate Specificity; Translational Research, Biomedical

2016
Getting a Handle on RAS-targeted Therapies: Cysteine Directed Inhibitors.
    Mini reviews in medicinal chemistry, 2016, Volume: 16, Issue:5

    Topics: Allosteric Regulation; Antineoplastic Agents; Cysteine; Guanosine Diphosphate; Humans; Mutation; Neoplasms; ras Proteins; Small Molecule Libraries

2016
Covalent targeting of acquired cysteines in cancer.
    Current opinion in chemical biology, 2016, Volume: 30

    Topics: Cysteine; Humans; Molecular Targeted Therapy; Mutation; Neoplasms; Precision Medicine; Proto-Oncogene Proteins p21(ras)

2016
Molecular mechanisms mediating oxidative stress-induced T-cell suppression in cancer.
    Advances in enzyme regulation, 2009, Volume: 49, Issue:1

    Topics: Actin Depolymerizing Factors; Actins; Cysteine; Cytoskeleton; Granulocytes; Humans; Macrophages; Neoplasms; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Sulfhydryl Compounds; T-Lymphocytes

2009
Cysteinyl leukotrienes and their receptors: molecular and functional characteristics.
    Pharmacology, 2010, Volume: 85, Issue:6

    Topics: Animals; Cardiovascular Diseases; Cysteine; Female; Gene Expression Regulation; Humans; Leukotrienes; Male; Neoplasms; Neurosecretory Systems; Protein Conformation; Receptors, Leukotriene; Respiratory Hypersensitivity; Signal Transduction

2010
Matrix metalloproteinases.
    Current medicinal chemistry, 2010, Volume: 17, Issue:31

    Topics: Cardiovascular Diseases; Cysteine; Extracellular Matrix; Gene Expression Regulation, Enzymologic; Humans; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Neoplasms; Substrate Specificity; Tissue Inhibitor of Metalloproteinases; Zinc Compounds

2010
Methylselenocysteine: a promising antiangiogenic agent for overcoming drug delivery barriers in solid malignancies for therapeutic synergy with anticancer drugs.
    Expert opinion on drug delivery, 2011, Volume: 8, Issue:6

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Cysteine; Drug Synergism; Humans; Neoplasms; Organoselenium Compounds; Selenocysteine

2011
Interventions that induce modifications in the tumor microenvironment.
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2011, Volume: 15, Issue:5

    Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antineoplastic Agents; Cell Adhesion; Cell Hypoxia; Clinical Trials, Phase III as Topic; Combined Modality Therapy; Cysteine; Cytotoxins; Drug Screening Assays, Antitumor; Extracellular Matrix; Genetic Therapy; Humans; Immunotherapy; Molecular Targeted Therapy; Neoplasm Proteins; Neoplasms; Neoplasms, Experimental; Neoplastic Stem Cells; Neovascularization, Pathologic; Organoselenium Compounds; Radiation Tolerance; Radiotherapy; Selenocysteine; Signal Transduction; Stromal Cells; Tumor Microenvironment

2011
Immunosuppressive cells and tumour microenvironment: focus on mesenchymal stem cells and myeloid derived suppressor cells.
    Histology and histopathology, 2011, Volume: 26, Issue:7

    Topics: Animals; Cysteine; Humans; Immune Tolerance; Immunotherapy; Lymphocytes, Tumor-Infiltrating; Mesenchymal Stem Cells; Models, Immunological; Myeloid Cells; Neoplasm Metastasis; Neoplasms; Neoplastic Stem Cells; Reactive Oxygen Species; T-Lymphocytes, Regulatory; Tumor Microenvironment

2011
Nitric oxide and cancer: the emerging role of S-nitrosylation.
    Current molecular medicine, 2012, Volume: 12, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cysteine; Epigenesis, Genetic; Humans; Neoplasms; Nitric Oxide; Nitric Oxide Synthase; Protein Processing, Post-Translational; Signal Transduction; Tumor Microenvironment

2012
Interacting with thioredoxin-1--disease or no disease?
    Antioxidants & redox signaling, 2013, Mar-20, Volume: 18, Issue:9

    Topics: Animals; Atherosclerosis; Blood Vessels; Cardiovascular System; Cysteine; Cystine; Diabetes Mellitus, Type 2; Heart Diseases; Humans; Hydrogen Peroxide; Mice; Models, Cardiovascular; Molecular Targeted Therapy; Myocardium; NADP; Neoplasm Proteins; Neoplasms; Oxidation-Reduction; Peroxiredoxins; Reactive Oxygen Species; Signal Transduction; Thioredoxins

2013
Protein farnesyltransferase inhibitors.
    Current medicinal chemistry, 2002, Volume: 9, Issue:10

    Topics: Alkyl and Aryl Transferases; Angiogenesis Inducing Agents; Animals; Antineoplastic Agents; Apoptosis; Cell Membrane; Clinical Trials as Topic; Cysteine; Enzyme Inhibitors; Farnesyltranstransferase; Humans; Neoplasms; Polyisoprenyl Phosphates; Protein Prenylation; Protein Processing, Post-Translational; ras Proteins; Sesquiterpenes

2002
Sulfur containing amino acids and human disease.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2004, Volume: 58, Issue:1

    Topics: Animals; Cysteine; Down Syndrome; Humans; Methionine; Neoplasms; Sulfur

2004
Multiple roles for cysteine cathepsins in cancer.
    Cell cycle (Georgetown, Tex.), 2004, Volume: 3, Issue:12

    Topics: Animals; Cathepsins; Cysteine; Humans; Models, Biological; Neoplasms

2004
Molecular nuclear imaging: the radiopharmaceuticals (review).
    Cancer biotherapy & radiopharmaceuticals, 2005, Volume: 20, Issue:2

    Topics: Animals; Annexins; Antibodies, Monoclonal; Antigens; Apoptosis; Cysteine; Diagnostic Imaging; DNA; Fluorodeoxyglucose F18; Glycolysis; Humans; Indium Radioisotopes; Ligands; Lymphoma; Myocardial Infarction; Neoplasms; Octreotide; Organotechnetium Compounds; Positron-Emission Tomography; Radiopharmaceuticals; Technetium; Tomography, Emission-Computed, Single-Photon; Yttrium Radioisotopes

2005
[Glutathione: its biosynthesis, induction agents and concentrations in selected diseases].
    Medycyna pracy, 2004, Volume: 55, Issue:6

    Topics: Animals; Cysteine; Cystine; Glutamic Acid; Glutathione; Glycine; Humans; Male; Neoplasms

2004
[The role of cysteine cathepsins and their inhibitors in physiological and neoplastic processes].
    Postepy biochemii, 2000, Volume: 46, Issue:1

    Topics: Animals; Cathepsins; Cysteine; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Humans; Neoplasms

2000
Selenium protects against toxicity induced by anticancer drugs and augments antitumor activity: a highly selective, new, and novel approach for the treatment of solid tumors.
    Clinical colorectal cancer, 2005, Volume: 5, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cysteine; Drug Synergism; Humans; Irinotecan; Mice; Neoplasms; Organoselenium Compounds; Rats; Selenocysteine; Selenomethionine

2005
Chemical forms of selenium for cancer prevention.
    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2005, Volume: 19, Issue:2-3

    Topics: Anticarcinogenic Agents; Chromatography; Chromatography, High Pressure Liquid; Cysteine; Food; Glutathione Peroxidase; Humans; Iodide Peroxidase; Mass Spectrometry; Methionine Sulfoxide Reductases; Models, Chemical; Neoplasms; Organoselenium Compounds; Selenium; Selenocysteine; Selenoprotein P; Selenoprotein W; Thioredoxin-Disulfide Reductase

2005
Transcriptional regulation via cysteine thiol modification: a novel molecular strategy for chemoprevention and cytoprotection.
    Molecular carcinogenesis, 2006, Volume: 45, Issue:6

    Topics: Cysteine; Humans; Neoplasms; Prostaglandin D2; Signal Transduction; Sulfhydryl Compounds; Transcription Factors; Transcription, Genetic

2006
The redox regulation of thiol dependent signaling pathways in cancer.
    Current pharmaceutical design, 2006, Volume: 12, Issue:34

    Topics: Animals; Antioxidants; Apoptosis; Cell Membrane; Cell Nucleus; Cell Proliferation; Cell Transformation, Neoplastic; Cysteine; Cytosol; Humans; Neoplasms; Oxidation-Reduction; Oxidative Stress; Phosphoric Monoester Hydrolases; Protein Kinases; Protein Processing, Post-Translational; Proteins; Reactive Nitrogen Species; Reactive Oxygen Species; Signal Transduction; Sulfhydryl Compounds; Transcription Factors

2006
Thiols and the chemoprevention of cancer.
    Current opinion in pharmacology, 2007, Volume: 7, Issue:4

    Topics: Animals; Anticarcinogenic Agents; Antioxidants; Carcinogens; Cysteine; Drug Delivery Systems; Glutathione; Humans; Neoplasms; Oxidation-Reduction; Oxidative Stress; Signal Transduction; Sulfhydryl Compounds

2007
A prototypic matricellular protein in the tumor microenvironment--where there's SPARC, there's fire.
    Journal of cellular biochemistry, 2008, Jun-01, Volume: 104, Issue:3

    Topics: Animals; Biological Evolution; Cell Movement; Computational Biology; Cysteine; Disease Progression; Glycoproteins; Humans; Models, Biological; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms; Neovascularization, Pathologic; Osteonectin; Systems Biology

2008
Redox signaling and cancer: the role of "labile" iron.
    Cancer letters, 2008, Jul-18, Volume: 266, Issue:1

    Topics: Adaptation, Biological; Cysteine; Humans; Hydrogen Peroxide; Iron; Mutation; Neoplasms; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Signal Transduction

2008
Protein cysteine thiol nitrosation: maker or marker of reactive nitrogen species-induced nonerythroid cellular signaling?
    Nitric oxide : biology and chemistry, 2008, Volume: 19, Issue:2

    Topics: Cysteine; Humans; Neoplasms; Nitrosation; Proteins; Reactive Nitrogen Species; Signal Transduction

2008
Chemical radiation sensitizers and protectors: recent developments.
    Clinical bulletin, 1981, Volume: 11, Issue:1

    Topics: Amifostine; Cysteamine; Cysteine; DNA, Neoplasm; Humans; Neoplasms; Nitroimidazoles; Nucleic Acid Conformation; Oxygen; Radiation-Protective Agents; Radiation-Sensitizing Agents; Sulfhydryl Compounds

1981
Role of cysteine and glutathione in HIV infection and cancer cachexia: therapeutic intervention with N-acetylcysteine.
    Advances in pharmacology (San Diego, Calif.), 1997, Volume: 38

    Topics: Acetylcysteine; Amino Acids; Cachexia; Cysteine; Glutathione; HIV Infections; Humans; Muscle, Skeletal; Neoplasms

1997
Role of cysteine and glutathione in HIV infection and other diseases associated with muscle wasting and immunological dysfunction.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1997, Volume: 11, Issue:13

    Topics: Animals; CD4-Positive T-Lymphocytes; Colitis, Ulcerative; Crohn Disease; Cysteine; Cystine; Fatigue Syndrome, Chronic; Glutamine; Glutathione; HIV Wasting Syndrome; Humans; Killer Cells, Natural; Models, Biological; Muscle, Skeletal; Muscular Diseases; Neoplasms; Sepsis; Wasting Syndrome; Wounds and Injuries

1997
Tumor-specific pyruvate kinase isoenzyme M2 involved in biochemical strategy of energy generation in neoplastic cells.
    Acta biochimica Polonica, 1997, Volume: 44, Issue:4

    Topics: Adenosine Triphosphate; Animals; Biomarkers, Tumor; Cysteine; Energy Metabolism; Enzyme Inhibitors; Genotype; Glycolysis; Humans; Isoenzymes; Mice; Neoplasms; Phenotype; Pyruvate Kinase; Rats; Sulfhydryl Compounds

1997
Selenium metabolism, selenoproteins and mechanisms of cancer prevention: complexities with thioredoxin reductase.
    Carcinogenesis, 1999, Volume: 20, Issue:9

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Cell Cycle Proteins; Cell Division; Cysteine; Enzyme Inhibitors; Gene Expression Regulation; Humans; Methylation; Mice; Molecular Weight; Neoplasms; Neoplasms, Experimental; Oxidation-Reduction; Protein Kinase C; Proteins; Selenium; Selenocysteine; Selenoproteins; Thioredoxin-Disulfide Reductase; Thioredoxins; Transcription Factors

1999
Thymidylate synthetase - a target enzyme in cancer chemotherapy.
    Biochimica et biophysica acta, 1977, Dec-23, Volume: 473, Issue:2

    Topics: Animals; Binding, Competitive; Cysteine; Deoxyuracil Nucleotides; DNA, Neoplasm; Female; Floxuridine; Humans; In Vitro Techniques; Iodoacetamide; Kinetics; Male; Methyltransferases; Models, Chemical; Neoplasms; Tetrahydrofolates; Thionucleotides; Thymidylate Synthase; Thymine Nucleotides

1977
Glutathione-dependent bioactivation of xenobiotics: implications for mutagenicity and carcinogenicity.
    Princess Takamatsu symposia, 1990, Volume: 21

    Topics: Animals; Antineoplastic Agents; Cysteine; DNA; DNA Damage; Glutathione; Mice; Mutagenesis; Neoplasms; Nitroimidazoles; Rats; Xenobiotics

1990
Polarography of proteins, analytical principles and applications in biological and clinical chemistry.
    Methods of biochemical analysis, 1971, Volume: 19

    Topics: Adult; Blood Proteins; Cathepsins; Cerebrospinal Fluid Proteins; Chemistry, Clinical; Cobalt; Cysteine; Cystine; Disease; Electrophoresis; Enzyme Precursors; Globulins; Humans; Hydroxides; Infant; Infant, Newborn; Mathematics; Methods; Mucoproteins; Neoplasms; Pepsin A; Peptide Hydrolases; Polarography; Potassium; Protein Denaturation; Proteins; Proteinuria; Serum Albumin; Temperature; Trypsin; Trypsin Inhibitors

1971

Trials

6 trial(s) available for cysteine and Neoplasms

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosphate; Adsorption; Adult; Africa, Eastern; Aged; Air Pollutants; Air Pollution; Air Pollution, Indoor; Alcohol Drinking; Allergens; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Anti-Bacterial Agents; Antibodies; Antibodies, Immobilized; Antigen Presentation; Antigens, CD; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Aptamers, Nucleotide; Asthma; Asthma, Exercise-Induced; Atrophy; Autophagy; Azoospermia; Bacillus cereus; Bacterial Infections; Beclin-1; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Biofouling; Biological Monitoring; Biomarkers; Biomarkers, Tumor; Biosensing Techniques; Blastocyst; Bone Neoplasms; Bone Regeneration; Bronchoconstriction; Burkitt Lymphoma; C9orf72 Protein; Campylobacter; Campylobacter Infections; Campylobacter jejuni; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Cardiomyopathies; Caregivers; Carmine; Case-Control Studies; Catalysis; Cattle; Cause of Death; CCAAT-Enhancer-Binding Protein-alpha; CD8-Positive T-Lymphocytes; Cefepime; Cell Differentiation; Cell Line, Tumor; Cell Nucleus; Cell Transdifferentiation; Chelating Agents; Chemical and Drug Induced Liver Injury, Chronic; Chemoradiotherapy, Adjuvant; Child; Child, Preschool; China; Chlorquinaldol; Cholangiocarcinoma; Cholera; Chromatin; Clinical Trials as Topic; Cognitive Dysfunction; Cohort Studies; Colonic Neoplasms; Colorectal Neoplasms; Colorimetry; Cooking; Coordination Complexes; COVID-19; Creatinine; CRISPR-Cas Systems; Critical Care; Critical Illness; Cross-Sectional Studies; Cryopreservation; Cryoprotective Agents; Cysteine; Cytokines; Device Removal; Diet; Diet, High-Fat; Diet, Mediterranean; Dietary Supplements; Dimethyl Sulfoxide; Dipeptides; Disease Models, Animal; Dithiothreitol; DNA; DNA Repeat Expansion; DNA, Bacterial; DNA, Complementary; Dopamine; Electrochemical Techniques; Electrodes; Endocannabinoids; Environmental Exposure; Environmental Monitoring; Environmental Pollutants; Enzyme-Linked Immunosorbent Assay; Erlotinib Hydrochloride; Escherichia coli; Escherichia coli O157; Esophageal Neoplasms; Esophagitis, Peptic; Ethylene Glycol; Europium; Exanthema; Fallopian Tubes; Feces; Female; Fertilization in Vitro; Fluoresceins; Fluorescent Dyes; Follicle Stimulating Hormone; Follow-Up Studies; Food Microbiology; Forced Expiratory Volume; Forkhead Transcription Factors; Frontotemporal Dementia; G-Quadruplexes; Galactose; Gastroenteritis; Gastrointestinal Diseases; Gastrointestinal Microbiome; Gastrointestinal Neoplasms; Gastrointestinal Tract; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genital Neoplasms, Female; Genome-Wide Association Study; Genome, Viral; Genomics; Genotype; Glucose; Glutathione; Glycerol; Gold; Graphite; GTPase-Activating Proteins; Heat-Shock Proteins; Heme Oxygenase-1; Hepacivirus; Hepatitis C; Hepatocytes; Histamine; Histocompatibility Antigens Class II; Hoarseness; Hospice and Palliative Care Nursing; Humans; Hydrogen; Hydrogen Peroxide; Hydrogen Sulfide; Hydroxybenzoates; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperthermia, Induced; Hysteroscopy; Immunoassay; Indigo Carmine; Inflammation; Inflammatory Bowel Diseases; Insulin Resistance; Intensive Care Units; Interleukin-11; Interleukin-6; Interleukins; Iodine Radioisotopes; Iran; Iridium; Islets of Langerhans; Kinetics; Lactation; Lactobacillus; Lactobacillus plantarum; Lamins; Latin America; Lead; Lectins; Leukopenia; Ligands; Limit of Detection; Lipopolysaccharides; Lipoprotein Lipase; Liver; Liver Cirrhosis; Liver Neoplasms; Lolium; Luminescent Measurements; Luminol; Lung; Luteinizing Hormone; Macrophages; Magnetic Phenomena; Magnetic Resonance Imaging; Male; Malnutrition; Maltose; Manganese Compounds; Maternal Nutritional Physiological Phenomena; Melatonin; Metabolic Engineering; Metal Nanoparticles; Metallocenes; Metaplasia; Methicillin-Resistant Staphylococcus aureus; Methylation; Mevalonic Acid; Mexico; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microbial Sensitivity Tests; Microbiota; MicroRNAs; Milk; Mitomycin; Molecular Diagnostic Techniques; Molecular Docking Simulation; Monte Carlo Method; Moringa oleifera; Multiple Sclerosis; Muscle Strength; Muscle, Skeletal; Nanocomposites; Nanotubes, Carbon; Neoadjuvant Therapy; Neoplasms; Neurodegenerative Diseases; Neurotransmitter Agents; NF-E2-Related Factor 2; Nickel; Nitrogen Dioxide; Non-alcoholic Fatty Liver Disease; Nucleic Acid Amplification Techniques; Nucleic Acid Hybridization; Nucleocapsid Proteins; Nutritional Status; Obesity; Osteogenesis; Osteosarcoma; Oxidation-Reduction; Oxides; Oxygen; Oxyquinoline; Pain; Palliative Care; Pancreatic Neoplasms; Pandemics; Particulate Matter; Peroxidase; Peroxidases; Phagocytosis; Phaseolus; Photothermal Therapy; Point-of-Care Systems; Polyethyleneimine; Polymers; Polymorphism, Single Nucleotide; Polysomnography; Postoperative Complications; Pregnancy; Pregnant Women; Prenatal Exposure Delayed Effects; Prevalence; Printing, Three-Dimensional; Probability; Probiotics; Prognosis; Prophages; Prospective Studies; Proteomics; Proto-Oncogene Proteins; Pseudomonas aeruginosa; Pseudomonas putida; Pulmonary Disease, Chronic Obstructive; Pulmonary Embolism; Pyridines; Pyrroles; Quality of Life; Quinolones; Rabbits; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Receptors, Histamine; Receptors, Histamine H2; Recombinases; Rectal Neoplasms; Reperfusion Injury; Respiration; Respiratory Function Tests; Respiratory Rate; Respiratory Sounds; Retrospective Studies; rho GTP-Binding Proteins; Risk Assessment; Risk Factors; RNA; RNA, Messenger; RNA, Ribosomal, 16S; Robotic Surgical Procedures; Running; Rural Population; Saccharomyces cerevisiae; Salpingectomy; Sarcopenia; SARS-CoV-2; Seeds; Semen; Sensitivity and Specificity; Sepsis; Shock, Septic; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Skin Neoplasms; Sleep Apnea, Obstructive; Soil; Spain; Spectrum Analysis, Raman; Sperm Retrieval; Spermatozoa; Spirometry; Staphylococcus aureus; STAT3 Transcription Factor; Stereoisomerism; Sterilization, Tubal; Stroke Volume; Sulfadiazine; Sulfites; Superoxide Dismutase; Surface Plasmon Resonance; tau Proteins; Testis; Testosterone; Thioredoxin-Disulfide Reductase; Thyroid Neoplasms; Thyroidectomy; Trans-Activators; Transcription Factor AP-1; Treatment Outcome; Triazoles; Triclosan; Trifluridine; Tumor Microenvironment; Tumor Necrosis Factor-alpha; United States; Uracil; Vagina; Vegetables; Ventricular Function, Left; Ventricular Pressure; Vibrio cholerae; Vietnam; Virulence; Vital Capacity; Vitrification; Walking; Water; Water Pollutants, Radioactive; Whole Genome Sequencing; Wind; YAP-Signaling Proteins; Zeolites; Zinc Oxide

2023
Pharmacokinetics and pharmacodynamics of mesna-mediated plasma cysteine depletion.
    Journal of clinical pharmacology, 2003, Volume: 43, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Area Under Curve; Carboplatin; Chromatography, High Pressure Liquid; Cysteine; Female; Half-Life; Humans; Ifosfamide; Male; Mesna; Metabolic Clearance Rate; Middle Aged; Models, Biological; Neoplasms; Protective Agents

2003
Monitoring paracetamol metabolism after single and repeated administration in pediatric patients with neoplastic diseases.
    International journal of clinical pharmacology and therapeutics, 2007, Volume: 45, Issue:9

    Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Antineoplastic Agents; Benzoquinones; Child; Child, Preschool; Cysteine; Drug Administration Schedule; Drug Interactions; Humans; Imines; Infant; Neoplasms; Oxidation-Reduction

2007
Intravenous ifosfamide/mesna is associated with depletion of plasma thiols without depletion of leukocyte glutathione.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:4

    Topics: Acetaldehyde; Antineoplastic Agents, Alkylating; Cysteine; Dose-Response Relationship, Drug; Glutathione; Homocysteine; Humans; Ifosfamide; Infusions, Intravenous; Leukocytes; Mesna; Neoplasms; Oxidation-Reduction; Protective Agents; Sulfhydryl Compounds

2000
[Effect of cepharanthin on radiotherapy induced leukopenia].
    Rinsho hoshasen. Clinical radiography, 1990, Volume: 35, Issue:4

    Topics: Adrenochrome; Alkaloids; Benzylisoquinolines; Cysteine; Female; Humans; Leukopenia; Neoplasms; Radiation-Protective Agents; Radiotherapy; Randomized Controlled Trials as Topic

1990
[Clinical efficacy of Z-100 for the treatment of leukopenia caused by radiotherapy--a multi-center double-blind comparative study with L-cysteine].
    Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1990, Aug-25, Volume: 50, Issue:8

    Topics: Adjuvants, Immunologic; Adult; Aged; Aged, 80 and over; Cysteine; Double-Blind Method; Female; Humans; Japan; Leukopenia; Lipids; Male; Mannans; Middle Aged; Neoplasms; Radiotherapy

1990

Other Studies

206 other study(ies) available for cysteine and Neoplasms

ArticleYear
Assembly of gold nanorods with L-cysteine reduced graphene oxide for highly efficient NIR-triggered photothermal therapy.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2022, Feb-05, Volume: 266

    Topics: Cell Line, Tumor; Cysteine; Gold; Graphite; Humans; Nanotubes; Neoplasms; Phototherapy; Photothermal Therapy

2022
Cysteine Restriction in Murine L929 Fibroblasts as an Alternative Strategy to Methionine Restriction in Cancer Therapy.
    International journal of molecular sciences, 2021, Oct-27, Volume: 22, Issue:21

    Topics: Animals; Caloric Restriction; Cell Line; Cysteine; Diet; Fibroblasts; Methionine; Mice; Neoplasms

2021
Computational Study Reveals the Role of Water Molecules in the Inhibition Mechanism of LAT1 by 1,2,3-Dithiazoles.
    Journal of chemical information and modeling, 2021, 12-27, Volume: 61, Issue:12

    Topics: Cysteine; Humans; Large Neutral Amino Acid-Transporter 1; Ligands; Neoplasms; Water

2021
Molecular basis for redox control by the human cystine/glutamate antiporter system xc
    Nature communications, 2021, 12-08, Volume: 12, Issue:1

    Topics: Amino Acid Transport System y+; Antiporters; Biochemistry; Cryoelectron Microscopy; Cysteine; Cystine; Fusion Regulatory Protein 1, Heavy Chain; Glutamic Acid; Glutathione; HEK293 Cells; Humans; Neoplasms; Oxidation-Reduction; Reactive Oxygen Species; Up-Regulation

2021
Methods for accurate and reproducible studies of pharmacological effects of selenium in cancer.
    Methods in enzymology, 2022, Volume: 662

    Topics: Cysteine; Humans; Neoplasms; Selenium; Selenium Compounds; Selenoproteins

2022
Core cysteine residues in the Plasminogen-Apple-Nematode (PAN) domain are critical for HGF/c-MET signaling.
    Communications biology, 2022, 07-01, Volume: 5, Issue:1

    Topics: Animals; Cysteine; Hepatocyte Growth Factor; Malus; Nematoda; Neoplasms; Plasminogen; Serine Proteases

2022
Self-Assembled Aza-Boron-Dipyrromethene for Ferroptosis-Boosted Sonodynamic Therapy.
    Angewandte Chemie (International ed. in English), 2022, 10-10, Volume: 61, Issue:41

    Topics: Boron; Cell Line, Tumor; Cysteine; Ferroptosis; Humans; Nanoparticles; Neoplasms; Porphobilinogen; Reactive Oxygen Species; Singlet Oxygen

2022
PEGylation of anti-MerTK Antibody Modulates Ocular Biodistribution.
    Bioconjugate chemistry, 2022, 10-19, Volume: 33, Issue:10

    Topics: Animals; Antibodies; c-Mer Tyrosine Kinase; Cysteine; Mice; Neoplasms; Phagocytosis; Polyethylene Glycols; Polymers; Retinal Pigments; Tissue Distribution

2022
Novel Calcium-Binding Ablating Mutations Induce Constitutive RET Activity and Drive Tumorigenesis.
    Cancer research, 2022, 10-17, Volume: 82, Issue:20

    Topics: Calcium; Calmodulin; Carcinogenesis; Cysteine; Disulfides; Drosophila Proteins; Humans; Ligands; Multiple Endocrine Neoplasia Type 2a; Mutation; Neoplasms; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret

2022
Inhibition of alanine-serine-cysteine transporter 2-mediated auto-enhanced photodynamic cancer therapy of co-nanoassembly between V-9302 and photosensitizer.
    Journal of colloid and interface science, 2023, Volume: 629, Issue:Pt B

    Topics: Animals; Cell Line, Tumor; Cysteine; Glutamine; Mice; Nanoparticles; Neoplasms; Photochemotherapy; Photosensitizing Agents; Reactive Oxygen Species

2023
A Small Molecule Reacts with the p53 Somatic Mutant Y220C to Rescue Wild-type Thermal Stability.
    Cancer discovery, 2023, 01-09, Volume: 13, Issue:1

    Topics: Cysteine; Humans; Mutation; Neoplasms; Tumor Suppressor Protein p53

2023
Computational analysis of prodomain cysteines in human TGF-β proteins reveals frequent loss of disulfide-dependent regulation in tumors.
    G3 (Bethesda, Md.), 2022, 12-01, Volume: 12, Issue:12

    Topics: Cysteine; Disulfides; Humans; Neoplasms; Protein Binding; Transforming Growth Factor beta

2022
Gold Nanoparticle-Incorporated Chitosan Nanogels as a Theranostic Nanoplatform for CT Imaging and Tumour Chemotherapy.
    International journal of nanomedicine, 2022, Volume: 17

    Topics: Chitosan; Cysteine; Doxorubicin; Drug Carriers; Gold; Humans; Hydrogen-Ion Concentration; Metal Nanoparticles; Muramidase; Nanogels; Nanoparticles; Neoplasms; Polymers; Precision Medicine; Theranostic Nanomedicine; Tomography, X-Ray Computed

2022
A vinyl-decorated covalent organic framework for ferroptotic cancer therapy
    Journal of materials chemistry. B, 2022, 11-09, Volume: 10, Issue:43

    Topics: Cysteine; Ferroptosis; Glutathione; Humans; Metal-Organic Frameworks; Neoplasms

2022
Optimizing phenyl selenide-based BODIPYs as fluorescent probes for diagnosing cancer and drug-induced liver injury
    Chemical communications (Cambridge, England), 2022, Nov-10, Volume: 58, Issue:90

    Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Cysteine; Fluorescent Dyes; Liver; Mice; Neoplasms

2022
Fragment Optimization of Reversible Binding to the Switch II Pocket on KRAS Leads to a Potent, In Vivo Active KRAS
    Journal of medicinal chemistry, 2022, 11-10, Volume: 65, Issue:21

    Topics: Cysteine; Genes, ras; Humans; Mutation; Neoplasms; Proto-Oncogene Proteins p21(ras)

2022
A 'double locked' ratiometric fluorescent probe for detection of cysteine in a viscous system and its application in cancer cells.
    Organic & biomolecular chemistry, 2023, 01-18, Volume: 21, Issue:3

    Topics: Cysteine; Fluorescent Dyes; HeLa Cells; Humans; Neoplasms; Spectrometry, Fluorescence; Viscosity

2023
Tryptophan Metabolism Acts as a New Anti-Ferroptotic Pathway to Mediate Tumor Growth.
    Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023, Volume: 10, Issue:6

    Topics: Cysteine; Humans; Lipid Peroxidation; Neoplasms; Serotonin; Tryptophan

2023
Tyrosinase-Related Protein2 Peptide with Replacement of N-Terminus Residue by Cysteine Binds to H-2K
    Bioconjugate chemistry, 2023, 02-15, Volume: 34, Issue:2

    Topics: Animals; Antigens; CpG Islands; Cysteine; DNA; Mice; Mice, Inbred C57BL; Monophenol Monooxygenase; Neoplasms; Ovalbumin; Peptide Fragments; Peptides; T-Lymphocytes, Cytotoxic

2023
Comprehensive landscape of the IPAF inflammasomes in pan-cancer: A bulk omics research and single-cell sequencing validation.
    Computers in biology and medicine, 2023, Volume: 155

    Topics: Cysteine; Databases, Factual; Humans; Immunotherapy; Inflammasomes; Neoplasms

2023
Comprehensive Metabolic Tracing Reveals the Origin and Catabolism of Cysteine in Mammalian Tissues and Tumors.
    Cancer research, 2023, 05-02, Volume: 83, Issue:9

    Topics: Animals; Carcinogenesis; Cysteine; Cystine; Glutathione; Mammals; Mice; Neoplasms; Serine

2023
A Near-Infrared Fluorescent and Photoacoustic Probe for Visualizing Biothiols Dynamics in Tumor and Liver.
    Molecules (Basel, Switzerland), 2023, Feb-27, Volume: 28, Issue:5

    Topics: Animals; Cysteine; Fluorescent Dyes; Glutathione; Homocysteine; Liver; Mice; Neoplasms; Optical Imaging; Spectrometry, Fluorescence

2023
Cell-Based Drug Screening for Inhibitors of Autophagy Related 4B Cysteine Peptidase.
    Journal of visualized experiments : JoVE, 2023, 06-30, Issue:196

    Topics: Autophagy; Autophagy-Related Proteins; Cysteine; Drug Evaluation, Preclinical; Humans; Luciferases; Neoplasms; Peptide Hydrolases

2023
Chemical remodeling of a cellular chaperone to target the active state of mutant KRAS.
    Science (New York, N.Y.), 2023, 08-18, Volume: 381, Issue:6659

    Topics: Biological Products; Cyclophilin A; Cysteine; Humans; Immunophilins; Molecular Chaperones; Neoplasms; Proto-Oncogene Proteins p21(ras); Signal Transduction

2023
Assigning functionality to cysteines by base editing of cancer dependency genes.
    Nature chemical biology, 2023, Volume: 19, Issue:11

    Topics: Cysteine; Gene Editing; Humans; Neoplasms; Nuclear Proteins; Proteome; Proteomics

2023
Site-specific antibody masking enables conditional activation with different stimuli.
    New biotechnology, 2023, Dec-25, Volume: 78

    Topics: Cysteine; Humans; Neoplasms; Single-Chain Antibodies

2023
Covalent Peptide LSD1 Inhibitor Specifically Recognizes Cys360 in the Enzyme-Active Region.
    Journal of medicinal chemistry, 2023, Nov-23, Volume: 66, Issue:22

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cysteine; Enzyme Inhibitors; Histone Demethylases; Humans; Neoplasms; Peptides; Peptides, Cyclic

2023
Synthesis and Evaluation of Novel TLR2 Agonists as Potential Adjuvants for Cancer Vaccines.
    Journal of medicinal chemistry, 2020, 03-12, Volume: 63, Issue:5

    Topics: Adjuvants, Immunologic; Cancer Vaccines; Cysteine; Humans; Lipopeptides; Neoplasms; Stereoisomerism; Toll-Like Receptor 2

2020
Spatial oxidation of L-plastin downmodulates actin-based functions of tumor cells.
    Nature communications, 2019, 09-09, Volume: 10, Issue:1

    Topics: Actins; Alkylation; Cell Line, Tumor; Cell Movement; Cell Surface Extensions; Cysteine; Extracellular Matrix; Humans; Hydrogen Peroxide; Membrane Glycoproteins; Microfilament Proteins; Models, Biological; Mutation; Neoplasms; Oxidation-Reduction; Sulfhydryl Compounds; Thioredoxin Reductase 1

2019
Antiproliferative
    Molecules (Basel, Switzerland), 2019, Sep-10, Volume: 24, Issue:18

    Topics: Cell Line, Tumor; Computer Simulation; Cysteine; Gene Expression Regulation, Neoplastic; Humans; Kinesins; Neoplasms; Sirtuin 2; Solubility; Trityl Compounds

2019
Transsulfuration Activity Can Support Cell Growth upon Extracellular Cysteine Limitation.
    Cell metabolism, 2019, 11-05, Volume: 30, Issue:5

    Topics: A549 Cells; Animals; Cell Proliferation; Cysteine; Extracellular Space; Female; Gene Knockout Techniques; Hep G2 Cells; Heterografts; Humans; Male; MCF-7 Cells; Methionine; Mice; Mice, Inbred NOD; Mice, Nude; Mice, SCID; Neoplasms; Protamines; S-Adenosylhomocysteine; S-Adenosylmethionine; Serine; Tumor Burden

2019
A novel highly sensitive fluorescent probe for bioimaging biothiols and its applications in distinguishing cancer cells from normal cells.
    The Analyst, 2019, Nov-18, Volume: 144, Issue:23

    Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Cysteine; Fluorescent Dyes; Glutathione; HeLa Cells; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Limit of Detection; Mice; Microscopy, Confocal; Microscopy, Fluorescence; Naphthalimides; Neoplasms; Optical Imaging; RAW 264.7 Cells; Zebrafish

2019
The Transsulfuration Pathway Makes, the Tumor Takes.
    Cell metabolism, 2019, 11-05, Volume: 30, Issue:5

    Topics: Cysteine; Humans; Methionine; Methylation; Neoplasms

2019
A synthetic lethal drug combination mimics glucose deprivation-induced cancer cell death in the presence of glucose.
    The Journal of biological chemistry, 2020, 01-31, Volume: 295, Issue:5

    Topics: Amino Acid Transport System y+; Antineoplastic Combined Chemotherapy Protocols; Antiporters; Cell Death; Cell Line, Tumor; Cell Survival; Cysteine; Cystine; Dimerization; Glucose; Glucose Transporter Type 1; Glutamic Acid; Glutathione; Humans; Metabolome; NADP; Neoplasms; Oxidation-Reduction; Reactive Oxygen Species; Synthetic Drugs

2020
Secreted protein acidic and rich in cysteine and cancer: A homeostatic hormone?
    Cytokine, 2020, Volume: 127

    Topics: Cysteine; Homeostasis; Hormones; Humans; Neoplasms; Proteins

2020
New Derivatization Reagent for Detection of free Thiol-groups in Metabolites and Proteins in Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging.
    Analytical chemistry, 2020, 05-05, Volume: 92, Issue:9

    Topics: Acrylamide; Animals; Cysteine; Glutathione; Insulin; Mice; Neoplasms; Pancreas; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfhydryl Compounds; Swine; Transplantation, Heterologous

2020
Obtusaquinone: A Cysteine-Modifying Compound That Targets Keap1 for Degradation.
    ACS chemical biology, 2020, 06-19, Volume: 15, Issue:6

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cinnamates; Cyclohexanones; Cysteine; Humans; Kelch-Like ECH-Associated Protein 1; Mice; Neoplasms; Proteolysis

2020
Cysteine cathepsins L and X differentially modulate interactions between myeloid-derived suppressor cells and tumor cells.
    Cancer immunology, immunotherapy : CII, 2020, Volume: 69, Issue:9

    Topics: Cathepsin L; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Cysteine; Humans; Leukocytes, Mononuclear; Myeloid-Derived Suppressor Cells; Neoplasm Invasiveness; Neoplasms; PC-3 Cells

2020
Impact of Cysteine Residues on MHC Binding Predictions and Recognition by Tumor-Reactive T Cells.
    Journal of immunology (Baltimore, Md. : 1950), 2020, 07-15, Volume: 205, Issue:2

    Topics: Amino Acid Sequence; Antigen Presentation; Antigens, Neoplasm; CD8-Positive T-Lymphocytes; Cells, Cultured; Cysteine; Epitopes, T-Lymphocyte; HLA-A2 Antigen; Humans; Lymphocyte Activation; Neoplasms; Peptides; Protein Binding; Receptors, Antigen, T-Cell, alpha-beta; T-Cell Antigen Receptor Specificity

2020
Real-Time Imaging Redox Status in Biothiols and Ferric Metabolism of Cancer Cells in Ferroptosis Based on Switched Fluorescence Response of Gold Carbon Dots.
    Analytical chemistry, 2020, 08-18, Volume: 92, Issue:16

    Topics: Carbon; Cell Line, Tumor; Cysteine; Ferroptosis; Fluorescent Dyes; Glutathione; Gold; Humans; Iron; Light; Metal Nanoparticles; Microscopy, Confocal; Microscopy, Fluorescence; Neoplasms; Oxidation-Reduction; Piperazines; Quantum Dots

2020
A Platform for the Generation of Site-Specific Antibody-Drug Conjugates That Allows for Selective Reduction of Engineered Cysteines.
    Bioconjugate chemistry, 2020, 09-16, Volume: 31, Issue:9

    Topics: Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Cysteine; Duocarmycins; Humans; Hydrophobic and Hydrophilic Interactions; Immunoconjugates; Immunoglobulin G; Mice; Models, Molecular; Neoplasms; Oxidation-Reduction

2020
Polyamine pathway activity promotes cysteine essentiality in cancer cells.
    Nature metabolism, 2020, Volume: 2, Issue:10

    Topics: Animals; Cell Line, Tumor; Cell Survival; Cysteine; Female; Gene Knockout Techniques; Humans; Metabolic Networks and Pathways; Methionine; Mice; Neoplasms; Polyamines; Purine-Nucleoside Phosphorylase; Reactive Oxygen Species; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2020
On-chip protein separation with single-molecule resolution.
    Scientific reports, 2020, 09-17, Volume: 10, Issue:1

    Topics: Acrylic Resins; Calibration; Cell Line, Tumor; Cysteine; Electrophoresis, Polyacrylamide Gel; Humans; Lysine; Molecular Weight; Neoplasms; Protein Array Analysis; Proteins; Proteomics; Sodium Dodecyl Sulfate

2020
A New Strategy: Distinguishable Multi-substance Detection, Multiple Pathway Tracing Based on a New Site Constructed by the Reaction Process and Its Tumor Targeting.
    Journal of the American Chemical Society, 2020, 10-28, Volume: 142, Issue:43

    Topics: Animals; Cysteine; Fluorescent Dyes; Glutathione; HeLa Cells; Humans; Mice; Mice, Nude; Microscopy, Confocal; Neoplasms; Optical Imaging; Sulfhydryl Compounds; Sulfur Dioxide; Transplantation, Heterologous

2020
Energy metabolism as a regulator of ferroptosis.
    Cell cycle (Georgetown, Tex.), 2020, Volume: 19, Issue:22

    Topics: AMP-Activated Protein Kinases; Cysteine; Ferroptosis; Humans; Iron; Lipid Peroxidation; Mitochondria; Neoplasms; Neurodegenerative Diseases; Reactive Oxygen Species; Reperfusion Injury

2020
Cell-permeable CaaX-peptides affect K-Ras downstream signaling and promote cell death in cancer cells.
    The FEBS journal, 2021, Volume: 288, Issue:9

    Topics: Alkyl and Aryl Transferases; Amino Acid Sequence; Cysteine; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; MCF-7 Cells; Neoplasms; Peptides; Prenylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins p21(ras); Signal Transduction

2021
Virtual screening and repurposing of FDA-approved drugs from ZINC database to identify potential autophagy inhibitors exploiting autophagy related 4A cysteine peptidase as a target: potential as novel anti-cancer molecule.
    Journal of biomolecular structure & dynamics, 2022, Volume: 40, Issue:12

    Topics: Autophagy; Cysteine; Drug Repositioning; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Neoplasms; Peptide Hydrolases; Zinc

2022
Nailing Down a Notoriously Elusive Cancer Target: Direct Inhibition of MYC by a Covalent Small Molecule.
    Cell chemical biology, 2021, 01-21, Volume: 28, Issue:1

    Topics: Antineoplastic Agents; Cysteine; Drug Discovery; Fracture Fixation, Intramedullary; Neoplasms; Transcription Factors

2021
Continuous flow fabrication of Fmoc-cysteine based nanobowl infused core-shell like microstructures for pH switchable on-demand anti-cancer drug delivery.
    Biomaterials science, 2021, Feb-09, Volume: 9, Issue:3

    Topics: Animals; Antineoplastic Agents; Cysteine; Doxorubicin; Drug Delivery Systems; Hydrogen-Ion Concentration; Nanoparticles; Neoplasms

2021
The intrinsically disordered N-terminus of the voltage-dependent anion channel.
    PLoS computational biology, 2021, Volume: 17, Issue:2

    Topics: Algorithms; Animals; Anions; Apoptosis; Computer Simulation; Crystallography, X-Ray; Cysteine; Intrinsically Disordered Proteins; Lipid Bilayers; Mice; Mitochondria; Mitochondrial Membranes; Models, Molecular; Molecular Dynamics Simulation; Mutation; Neoplasms; Peptides; Protein Conformation; Protein Denaturation; Protein Domains; Software; Voltage-Dependent Anion Channel 1

2021
A Cysteine-Mediated Synthesis of Red Phosphorus Nanosheets.
    Angewandte Chemie (International ed. in English), 2021, 05-25, Volume: 60, Issue:22

    Topics: A549 Cells; Animals; Apoptosis; Boron Compounds; Cell Line; Cysteine; DNA Damage; Ferroptosis; Humans; Mice; Mice, Nude; Nanostructures; Neoplasms; Phosphorus; Reactive Oxygen Species; Reducing Agents; Transplantation, Heterologous

2021
mTORC1 couples cyst(e)ine availability with GPX4 protein synthesis and ferroptosis regulation.
    Nature communications, 2021, 03-11, Volume: 12, Issue:1

    Topics: Amino Acid Transport System y+; Cell Line, Tumor; Cysteine; Cystine; Ferroptosis; Gene Knockout Techniques; Glutathione; HEK293 Cells; Humans; Mechanistic Target of Rapamycin Complex 1; Neoplasms; Phospholipid Hydroperoxide Glutathione Peroxidase

2021
Femtomolar determination of an ovarian cancer biomarker (miR-200a) in blood plasma using a label free electrochemical biosensor based on L-cysteine functionalized ZnS quantum dots.
    Analytical methods : advancing methods and applications, 2021, 05-06, Volume: 13, Issue:17

    Topics: Biomarkers, Tumor; Biosensing Techniques; Cysteine; Humans; MicroRNAs; Neoplasms; Plasma; Quantum Dots; Sulfides; Zinc Compounds

2021
A near-infrared fluorescent probe for accurately diagnosing cancer by sequential detection of cysteine and H
    Chemical communications (Cambridge, England), 2021, May-14, Volume: 57, Issue:39

    Topics: Animals; Cell Line; Cysteine; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Mice; Molecular Structure; Neoplasms; Optical Imaging; Spectrometry, Fluorescence

2021
Generation of therapeutic immunoconjugates via Residue-Specific Conjugation Technology (RESPECT) utilizing a native cysteine in the light chain framework of Oryctolagus cuniculus.
    Cancer biology & therapy, 2017, 05-04, Volume: 18, Issue:5

    Topics: Aminobenzoates; Animals; Antibodies, Monoclonal; Cysteine; Humans; Immunoconjugates; Mesothelin; Mice; Neoplasms; Oligopeptides; Rabbits; Trastuzumab; Xenograft Model Antitumor Assays

2017
Design of short peptides to block BTLA/HVEM interactions for promoting anticancer T-cell responses.
    PloS one, 2017, Volume: 12, Issue:6

    Topics: Amino Acid Sequence; Cell Line; Cysteine; Drug Design; Humans; Neoplasms; Peptides; Protein Binding; Receptors, Immunologic; Receptors, Tumor Necrosis Factor, Member 14; T-Lymphocytes

2017
Mutations in Cancer Cause Gain of Cysteine, Histidine, and Tryptophan at the Expense of a Net Loss of Arginine on the Proteome Level.
    Biomolecules, 2017, 07-03, Volume: 7, Issue:3

    Topics: Amino Acid Substitution; Arginine; Cell Line, Tumor; Codon, Nonsense; Cysteine; Histidine; Humans; Neoplasms; Proteome; Tryptophan; Tumor Suppressor Protein p53

2017
Sensitizing effects of an organovanadium compound during adjuvant therapy with cyclophosphamide in a murine tumor model.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 93

    Topics: Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; Chemotherapy, Adjuvant; Cyclophosphamide; Cysteine; DNA Damage; Down-Regulation; Female; Mice; Neoplasms; Neovascularization, Pathologic; Oxidative Stress; Reactive Oxygen Species; Signal Transduction; Up-Regulation; Vanadium Compounds

2017
New Kid on the Block.
    Theranostics, 2017, Volume: 7, Issue:11

    Topics: Cathepsin B; Cathepsins; Cysteine; Humans; Neoplasms

2017
Nanofitin as a New Molecular-Imaging Agent for the Diagnosis of Epidermal Growth Factor Receptor Over-Expressing Tumors.
    Bioconjugate chemistry, 2017, 09-20, Volume: 28, Issue:9

    Topics: Animals; Antibodies, Monoclonal; Cell Line, Tumor; Cysteine; ErbB Receptors; Female; Humans; Maleimides; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Positron-Emission Tomography

2017
Cysteine residues are essential for dimerization of Hippo pathway components YAP2L and TAZ.
    Scientific reports, 2018, 02-22, Volume: 8, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cysteine; Hippo Signaling Pathway; Humans; Intracellular Signaling Peptides and Proteins; Neoplasms; Phosphoproteins; Protein Multimerization; Protein Serine-Threonine Kinases; Signal Transduction; Trans-Activators; Transcription Factors; Transcriptional Coactivator with PDZ-Binding Motif Proteins; YAP-Signaling Proteins

2018
Identification of a metabolic disposal route for the oncometabolite
    The Journal of biological chemistry, 2018, 05-25, Volume: 293, Issue:21

    Topics: Acetylation; Bacillus subtilis; Cysteine; Fumarates; Metabolomics; Neoplasms; Operon; Signal Transduction

2018
Influence of composition of cysteine-containing peptide-based chelators on biodistribution of
    Amino acids, 2018, Volume: 50, Issue:8

    Topics: Animals; Cell Line, Tumor; Chelating Agents; Cysteine; ErbB Receptors; Humans; Mice; Molecular Imaging; Molecular Probes; Neoplasm Transplantation; Neoplasms; Peptides; Recombinant Fusion Proteins; Technetium; Tissue Distribution

2018
The reactivity-driven biochemical mechanism of covalent KRAS
    Nature structural & molecular biology, 2018, Volume: 25, Issue:6

    Topics: Animals; Catalysis; Cysteine; Genes, ras; Humans; Kinetics; Mutation; Neoplasms; Protein Binding; ras Proteins

2018
Chemoproteomic Profiling Reveals Ethacrynic Acid Targets Adenine Nucleotide Translocases to Impair Mitochondrial Function.
    Molecular pharmaceutics, 2018, 06-04, Volume: 15, Issue:6

    Topics: Cell Line, Tumor; Cysteine; Drug Repositioning; Drug Screening Assays, Antitumor; Ethacrynic Acid; Humans; Mitochondria; Mitochondrial ADP, ATP Translocases; Neoplasms; Proteome; Proteomics; Reactive Oxygen Species

2018
Impact of Payload Hydrophobicity on the Stability of Antibody-Drug Conjugates.
    Molecular pharmaceutics, 2018, 07-02, Volume: 15, Issue:7

    Topics: Antibodies, Monoclonal; Antineoplastic Agents, Immunological; Chemistry, Pharmaceutical; Computer Simulation; Cysteine; Drug Stability; Dynamic Light Scattering; Fluorometry; Hydrophobic and Hydrophilic Interactions; Immunoconjugates; Immunoglobulin G; Neoplasms

2018
Increasing time on target: utilization of inhibitors of cysteine cathepsins to enhance the tumor retention of receptor-targeted agents.
    Chemical communications (Cambridge, England), 2018, Oct-04, Volume: 54, Issue:80

    Topics: Cathepsins; Cysteine; Cysteine Proteinase Inhibitors; HT29 Cells; Humans; Molecular Structure; Molecular Targeted Therapy; Neoplasms; Receptors, Neurotensin

2018
Tetrathiomolybdate induces dimerization of the metal-binding domain of ATPase and inhibits platination of the protein.
    Nature communications, 2019, 01-14, Volume: 10, Issue:1

    Topics: Antineoplastic Agents; Chelating Agents; Cisplatin; Copper; Copper-Transporting ATPases; Cross-Linking Reagents; Crystallography, X-Ray; Cysteine; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Inhibitors; Humans; Molybdenum; Neoplasms; Platinum; Protein Interaction Domains and Motifs; Protein Multimerization; Protein Structure, Secondary

2019
Selective and reversible modification of kinase cysteines with chlorofluoroacetamides.
    Nature chemical biology, 2019, Volume: 15, Issue:3

    Topics: Acetamides; Animals; Antineoplastic Agents; Cell Line; Cysteine; ErbB Receptors; Humans; Mice; Mice, Nude; Neoplasms; Phosphotransferases; Protein Kinase Inhibitors; Pyrimidines; Quinazolines; Structure-Activity Relationship; Xenograft Model Antitumor Assays

2019
Serum Metabolomics Study of Nonsmoking Female Patients with Non-Small Cell Lung Cancer Using Gas Chromatography-Mass Spectrometry.
    Journal of proteome research, 2019, 05-03, Volume: 18, Issue:5

    Topics: Adult; Aged; Amino Acids; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Case-Control Studies; Cysteine; Diagnosis, Differential; Diglycerides; Early Detection of Cancer; Energy Metabolism; Female; Gas Chromatography-Mass Spectrometry; Humans; Lipid Metabolism; Lung Neoplasms; Metabolome; Middle Aged; Neoplasms; Non-Smokers; Oxidative Stress; Sensitivity and Specificity; Serine

2019
Plug-and-Play Continuous Gas Flow Assembly of Cysteine-Inserted AuCu Nanobimetals for Folate-Receptor-Targeted Chemo-Phototherapy.
    ACS applied materials & interfaces, 2019, May-15, Volume: 11, Issue:19

    Topics: Cell Line, Tumor; Copper; Cysteine; Doxorubicin; Drug Delivery Systems; Endocytosis; Folate Receptors, GPI-Anchored; Folic Acid; Gases; Gold; Humans; Light; Neoplasms; Nitrogen; Phototherapy; Solutions

2019
CD8
    Nature, 2019, Volume: 569, Issue:7755

    Topics: Amino Acid Transport System y+; Animals; B7-H1 Antigen; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Cysteine; Female; Ferroptosis; Fusion Regulatory Protein 1, Heavy Chain; Humans; Immunotherapy; Interferon-gamma; Lipid Peroxidation; Melanoma; Mice; Neoplasms; Nivolumab; Reactive Oxygen Species; Treatment Outcome

2019
Ambidextrous Approach To Disrupt Redox Balance in Tumor Cells with Increased ROS Production and Decreased GSH Synthesis for Cancer Therapy.
    ACS applied materials & interfaces, 2019, Jul-31, Volume: 11, Issue:30

    Topics: Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cysteine; Cystine; Glutathione; Humans; Nanoparticles; Neoplasms; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Sulfasalazine; Zinc Oxide

2019
Engineering agatoxin, a cystine-knot peptide from spider venom, as a molecular probe for in vivo tumor imaging.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Agatoxins; Amino Acid Substitution; Animals; Carbocyanines; Cysteine; Cystine Knot Motifs; Female; Fluorescent Dyes; Humans; Integrin alphaVbeta3; K562 Cells; Mice; Mice, Nude; Mutagenesis, Site-Directed; Neoplasm Transplantation; Neoplasms; Protein Binding; Protein Engineering; Protein Folding

2013
Effect of binding affinity for siRNA on the in vivo antitumor efficacy of polyplexes.
    Biomaterials, 2013, Volume: 34, Issue:21

    Topics: Animals; Antineoplastic Agents; Apoptosis; Body Weight; Cell Line, Tumor; Chitosan; Cysteine; Female; Galactose; Gene Silencing; Humans; Intracellular Space; Mice; Mice, Inbred BALB C; Mice, Nude; Microscopy, Electron, Scanning; Neoplasms; Particle Size; Platelet Endothelial Cell Adhesion Molecule-1; Polymers; RNA, Small Interfering; Static Electricity; Tissue Distribution; Treatment Outcome; Vascular Endothelial Growth Factor A

2013
Cysteine-poor region-specific EpCAM monoclonal antibody recognizing native tumor cells with high sensitivity.
    Monoclonal antibodies in immunodiagnosis and immunotherapy, 2013, Volume: 32, Issue:2

    Topics: Animals; Antibodies, Monoclonal, Murine-Derived; Antibody Specificity; Antigens, Neoplasm; Biomarkers, Tumor; Cell Adhesion Molecules; Cysteine; Epithelial Cell Adhesion Molecule; Epitope Mapping; HEK293 Cells; Humans; Hybridomas; MCF-7 Cells; Mice; Mice, Inbred BALB C; Neoplasms; Neoplastic Cells, Circulating; Reagent Kits, Diagnostic; Reference Standards

2013
Site-specific PEGylation of a mutated-cysteine residue and its effect on tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL).
    Biomaterials, 2013, Volume: 34, Issue:36

    Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; Body Weight; Circular Dichroism; Cysteine; Electrophoresis, Polyacrylamide Gel; Kidney; Liver; Mice; Mice, Inbred BALB C; Mutation; Neoplasms; Polyethylene Glycols; Protein Stability; Protein Structure, Secondary; Rats; Rats, Sprague-Dawley; TNF-Related Apoptosis-Inducing Ligand

2013
Radiochemical and radiobiological assessment of a pyridyl-S-cysteine functionalized bombesin derivative labeled with the (99m)Tc(CO)3(+) core.
    Bioorganic & medicinal chemistry, 2013, Nov-01, Volume: 21, Issue:21

    Topics: Amino Acid Sequence; Aminocaproic Acid; Animals; Bombesin; Cell Line, Tumor; Cysteine; Humans; Mice; Mice, SCID; Neoplasms; Organotechnetium Compounds; Peptides; Radiopharmaceuticals; Receptors, Bombesin; Tissue Distribution; Tomography, Emission-Computed, Single-Photon

2013
Sandwich-format electrochemiluminescence assays for tumor marker based on PAMAM dendrimer-L-cysteine-hollow gold nanosphere nanocomposites.
    Biosensors & bioelectronics, 2014, Mar-15, Volume: 53

    Topics: Biomarkers, Tumor; Biosensing Techniques; Carcinoembryonic Antigen; Cysteine; Dendrimers; Gold; Humans; Metal Nanoparticles; Nanocomposites; Nanospheres; Neoplasms

2014
PFKFB3 regulates oxidative stress homeostasis via its S-glutathionylation in cancer.
    Journal of molecular biology, 2014, Feb-20, Volume: 426, Issue:4

    Topics: Amino Acid Sequence; Catalytic Domain; Cysteine; Energy Metabolism; Fructosediphosphates; Glucose; Glutathione Disulfide; Glycolysis; HeLa Cells; Homeostasis; Humans; Molecular Sequence Data; Neoplasms; Oxidative Stress; Phosphofructokinase-2; Protein Conformation; Reactive Oxygen Species; Sulfur

2014
A free cysteine prolongs the half-life of a homing peptide and improves its tumor-penetrating activity.
    Journal of controlled release : official journal of the Controlled Release Society, 2014, Feb-10, Volume: 175

    Topics: Amino Acid Sequence; Animals; Cysteine; Drug Delivery Systems; Half-Life; Mice; Mice, Inbred BALB C; Neoplasms; Oligopeptides

2014
Redox regulation of endothelial cell fate.
    Cellular and molecular life sciences : CMLS, 2014, Volume: 71, Issue:17

    Topics: Animals; Apoptosis; Cardiovascular Diseases; Cell Cycle; Cell Movement; Cell Transdifferentiation; Cysteine; Diabetes Mellitus; Endothelial Cells; Forkhead Transcription Factors; Humans; Hydrogen Sulfide; Inflammation; Models, Biological; Neoplasms; Neovascularization, Physiologic; NF-E2-Related Factor 2; Nitric Oxide; Obesity; Oxidation-Reduction; Oxidoreductases; Reactive Nitrogen Species; Reactive Oxygen Species

2014
A radiofluorinated divalent cystine knot peptide for tumor PET imaging.
    Molecular pharmaceutics, 2014, Nov-03, Volume: 11, Issue:11

    Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Cell Line, Tumor; Chromatography, High Pressure Liquid; Cysteine; Cystine-Knot Miniproteins; Epitopes; Female; Fluorine Radioisotopes; Humans; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Integrin alphaVbeta3; Liver; Mice; Mice, Nude; Molecular Sequence Data; Neoplasm Transplantation; Neoplasms; Oligopeptides; Peptides; Positron-Emission Tomography; Protease Inhibitors; Protein Binding; Trypsin

2014
Piperlongumine chemosensitizes tumor cells through interaction with cysteine 179 of IκBα kinase, leading to suppression of NF-κB-regulated gene products.
    Molecular cancer therapeutics, 2014, Volume: 13, Issue:10

    Topics: Cell Line, Tumor; Cell Proliferation; Cysteine; Dioxolanes; Dose-Response Relationship, Drug; Humans; I-kappa B Kinase; MCF-7 Cells; Neoplasms; NF-kappa B; Phosphorylation; Tumor Necrosis Factor-alpha

2014
Kynurenine aminotransferase III and glutamine transaminase L are identical enzymes that have cysteine S-conjugate β-lyase activity and can transaminate L-selenomethionine.
    The Journal of biological chemistry, 2014, Nov-07, Volume: 289, Issue:45

    Topics: Alkenes; Animals; Carbon-Sulfur Lyases; Cysteine; Histone Deacetylase Inhibitors; Humans; Kinetics; Liver; Mice; Neoplasms; Recombinant Proteins; Selenocysteine; Selenomethionine; Substrate Specificity; Tandem Mass Spectrometry; Transaminases

2014
Impacts of CD44 knockdown in cancer cells on tumor and host metabolic systems revealed by quantitative imaging mass spectrometry.
    Nitric oxide : biology and chemistry, 2015, Apr-30, Volume: 46

    Topics: Animals; Cysteine; Gene Knockdown Techniques; HCT116 Cells; Humans; Hyaluronan Receptors; Liver; Male; Mass Spectrometry; Metabolome; Metabolomics; Mice; Neoplasms; RNA Interference; RNA, Small Interfering; Transplantation, Heterologous

2015
Ainsliadimer A selectively inhibits IKKα/β by covalently binding a conserved cysteine.
    Nature communications, 2015, Mar-27, Volume: 6

    Topics: Allosteric Regulation; Allosteric Site; Amino Acid Sequence; Animals; Cell Line, Tumor; Conserved Sequence; Cysteine; HEK293 Cells; HeLa Cells; Humans; I-kappa B Kinase; Lactones; Mice; Neoplasms; NF-kappa B; RAW 264.7 Cells; Sesquiterpenes; Signal Transduction

2015
Fabrication and spectroscopic studies of folic acid-conjugated Fe3O4@Au core-shell for targeted drug delivery application.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2015, Sep-05, Volume: 148

    Topics: Antineoplastic Agents; Cysteine; Drug Carriers; Drug Delivery Systems; Folic Acid; Gold; Humans; Magnetite Nanoparticles; Neoplasms; Powder Diffraction; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction

2015
Bradykinin and cysteinyl leukotriene concentrations in cell-salvaged blood before and after passage through negatively charged filters during clinical use in cancer patients: a pilot study.
    Anaesthesia, 2015, Volume: 70, Issue:9

    Topics: Blood Transfusion, Autologous; Bradykinin; Cysteine; Female; Filtration; Humans; Leukapheresis; Leukotrienes; Male; Neoplasms; Pilot Projects

2015
Highly cytotoxic bioconjugated gold(I) complexes with cysteine-containing dipeptides.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2015, Jul-27, Volume: 21, Issue:31

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Coordination Complexes; Cysteine; Dipeptides; Gold; Humans; Neoplasms; Phosphines

2015
Hydrophobic Cysteine Poly(disulfide)-based Redox-Hypersensitive Nanoparticle Platform for Cancer Theranostics.
    Angewandte Chemie (International ed. in English), 2015, Aug-03, Volume: 54, Issue:32

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Cysteine; Disulfides; Docetaxel; Drug Carriers; Fluorescence Resonance Energy Transfer; HeLa Cells; Humans; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Nanoparticles; Neoplasms; Oxidation-Reduction; Particle Size; Polyethylene Glycols; Polymers; Taxoids; Theranostic Nanomedicine

2015
Highly selective two-photon imaging of cysteine in cancerous cells and tissues.
    Chemical communications (Cambridge, England), 2015, Oct-01, Volume: 51, Issue:76

    Topics: Animals; Cell Line, Tumor; Cysteine; Fluorescent Dyes; Glutathione; HeLa Cells; Hep G2 Cells; Homocysteine; Humans; Mice; Microscopy, Fluorescence, Multiphoton; Neoplasms; Optical Imaging; Spectrometry, Fluorescence

2015
Curation of the Mammalian Palmitoylome Indicates a Pivotal Role for Palmitoylation in Diseases and Disorders of the Nervous System and Cancers.
    PLoS computational biology, 2015, Volume: 11, Issue:8

    Topics: Cysteine; Databases, Protein; Humans; Lipoylation; Neoplasms; Nervous System Diseases; Palmitates; Proteome; Proteomics

2015
A peptide array-based serological protein kinase A activity assay and its application in cancer diagnosis.
    The Analyst, 2015, Oct-07, Volume: 140, Issue:19

    Topics: Amino Acid Sequence; Biomarkers, Tumor; Cyclic AMP-Dependent Protein Kinases; Cysteine; Enzyme Assays; Humans; Neoplasms; Octoxynol; Oligopeptides; Protein Array Analysis; Spectrometry, Fluorescence

2015
Molecular Magnetic Resonance Imaging of Tumor Response to Therapy.
    Scientific reports, 2015, Oct-06, Volume: 5

    Topics: Administration, Metronomic; Animals; Antibiotics, Antineoplastic; Caspase 3; Contrast Media; Cysteine; Doxorubicin; Female; HeLa Cells; Humans; Magnetic Resonance Imaging; Mice, Nude; Neoplasms; Quinolines; Treatment Outcome; Xenograft Model Antitumor Assays

2015
Theoretical studies of the role of C-terminal cysteines in the process of S-nitrosylation of human Src kinases.
    Journal of molecular modeling, 2016, Volume: 22, Issue:1

    Topics: Cysteine; Humans; Neoplasm Proteins; Neoplasms; Nitric Oxide; src-Family Kinases

2016
Mass spectrometry analysis of the oxidation states of the pro-oncogenic protein anterior gradient-2 reveals covalent dimerization via an intermolecular disulphide bond.
    Biochimica et biophysica acta, 2016, Volume: 1864, Issue:5

    Topics: Amino Acid Sequence; ATPases Associated with Diverse Cellular Activities; Carrier Proteins; Cysteine; Disulfides; DNA Helicases; Drug Resistance, Neoplasm; Humans; Mass Spectrometry; MCF-7 Cells; Mucoproteins; Mutation; Neoplasms; Oncogene Proteins; Oxidation-Reduction; Protein Multimerization; Proteins; Signal Transduction; Sulfenic Acids

2016
Stabilizing the cold plasma-stimulated medium by regulating medium's composition.
    Scientific reports, 2016, 05-13, Volume: 6

    Topics: Antineoplastic Agents; Culture Media; Cysteine; Free Radicals; Freezing; Helium; Humans; Hydrogen Peroxide; Methionine; Neoplasms; Radiation; Tyrosine

2016
Maleimide-functionalized closo-dodecaborate albumin conjugates (MID-AC): Unique ligation at cysteine and lysine residues enables efficient boron delivery to tumor for neutron capture therapy.
    Journal of controlled release : official journal of the Controlled Release Society, 2016, 09-10, Volume: 237

    Topics: Animals; Boron; Boron Compounds; Boron Neutron Capture Therapy; Cell Line; Cysteine; Drug Carriers; Female; Lysine; Maleimides; Mice; Mice, Inbred BALB C; Models, Molecular; Neoplasms; Serum Albumin, Bovine

2016
PGA1-induced apoptosis involves specific activation of H-Ras and N-Ras in cellular endomembranes.
    Cell death & disease, 2016, 07-28, Volume: 7, Issue:7

    Topics: Animals; Apoptosis; Calpain; Cell Line, Tumor; Cysteine; Embryo, Mammalian; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Intracellular Membranes; Mice; Neoplasms; Prostaglandins A; ras Proteins

2016
Divergent synthesis and identification of the cellular targets of deoxyelephantopins.
    Nature communications, 2016, 08-19, Volume: 7

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cysteine; Humans; Lactones; Molecular Targeted Therapy; Neoplasms; PPAR gamma; Proteomics; Recombinant Proteins; Sesquiterpenes; Zinc Fingers

2016
Phosphocysteine in the PRL-CNNM pathway mediates magnesium homeostasis.
    EMBO reports, 2016, Volume: 17, Issue:12

    Topics: Cation Transport Proteins; Cell Cycle Proteins; Crystallography, X-Ray; Cyclins; Cysteine; HEK293 Cells; Homeostasis; Humans; Magnesium; Membrane Proteins; Models, Molecular; Neoplasm Proteins; Neoplasms; Phosphorylation; Protein Binding; Protein Tyrosine Phosphatases; Signal Transduction

2016
Degenerate cysteine patterns mediate two redox sensing mechanisms in the papillomavirus E7 oncoprotein.
    Redox biology, 2017, Volume: 11

    Topics: Cell Nucleolus; Cell Transformation, Neoplastic; Cysteine; Cytoplasm; Disulfides; Neoplasms; Oxidation-Reduction; Oxidative Stress; Papillomavirus E7 Proteins; Protein Transport; Virus Replication

2017
Differential sensitivity of various human tumour-derived cell types to apoptosis by organic derivatives of selenium.
    The British journal of nutrition, 2009, Volume: 101, Issue:2

    Topics: Adenocarcinoma; Adolescent; Adult; Animals; Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Cysteine; Epithelial Cells; Female; Humans; Liver Neoplasms; Male; Melanoma; Middle Aged; Neoplasms; Neuroectodermal Tumors, Primitive, Peripheral; Organoselenium Compounds; Selenium Compounds; Selenocysteine; Selenomethionine; Skin Neoplasms

2009
Recognition of NY-ESO-1+ tumor cells by engineered lymphocytes is enhanced by improved vector design and epigenetic modulation of tumor antigen expression.
    Cancer immunology, immunotherapy : CII, 2009, Volume: 58, Issue:3

    Topics: Antigens, Neoplasm; Cell Line, Tumor; Cloning, Molecular; Cysteine; Cytokines; Epigenesis, Genetic; Genetic Vectors; Humans; Immunotherapy; Lymphocytes; Models, Genetic; Neoplasms; Peptides; Receptors, Antigen, T-Cell; T-Lymphocytes

2009
Modulation of DNA methylation by a sesquiterpene lactone parthenolide.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 329, Issue:2

    Topics: Alkylation; Animals; Antineoplastic Agents; Apoptosis; Catalytic Domain; Cell Cycle; Cell Line, Tumor; Cell Survival; Chromatin Immunoprecipitation; Cysteine; Cytokines; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Electrophoretic Mobility Shift Assay; Female; Humans; Immunoblotting; Lactones; Mice; Mice, Nude; Models, Molecular; Neoplasms; Promoter Regions, Genetic; Sesquiterpenes; Sp1 Transcription Factor; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays

2009
Site-specific polysialylation of an antitumor single-chain Fv fragment.
    Bioconjugate chemistry, 2009, May-20, Volume: 20, Issue:5

    Topics: Amines; Animals; Antineoplastic Agents; Binding Sites; Cell Line; Cysteine; Female; Half-Life; Humans; Mice; Mice, Inbred BALB C; Neoplasms; Protein Engineering; Sialic Acids; Single-Chain Antibodies; Substrate Specificity

2009
Targeting of epidermal growth factor receptor (EGFR)-expressing tumor cells with sterically stabilized affibody liposomes (SAL).
    Bioconjugate chemistry, 2009, Volume: 20, Issue:6

    Topics: Antibodies; Biological Transport; Cell Line, Tumor; Cysteine; ErbB Receptors; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Liposomes; Maleimides; Mitoxantrone; Nanostructures; Neoplasms; Phosphatidylethanolamines; Polyethylene Glycols; Recombinant Fusion Proteins; Substrate Specificity

2009
Intracellular beta-tubulin/chaperonin containing TCP1-beta complex serves as a novel chemotherapeutic target against drug-resistant tumors.
    Cancer research, 2009, Sep-01, Volume: 69, Issue:17

    Topics: Alkylation; Apoptosis; Binding Sites; Caspase 1; Cell Line, Transformed; Cell Line, Tumor; Chaperonin Containing TCP-1; Chaperonins; Cysteine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Activation; Humans; Mutagenesis, Site-Directed; Neoplasms; Peptide Fragments; Protein Binding; Proteomics; Tryptophan; Tubulin

2009
Nitrosative stress-induced s-glutathionylation of protein disulfide isomerase leads to activation of the unfolded protein response.
    Cancer research, 2009, Oct-01, Volume: 69, Issue:19

    Topics: 4-Aminobenzoic Acid; Amino Acid Sequence; Azo Compounds; Catalytic Domain; Cell Line, Tumor; Cysteine; Female; Glutathione; HL-60 Cells; Humans; Models, Molecular; Molecular Sequence Data; Neoplasms; Nitric Oxide; Ovarian Neoplasms; para-Aminobenzoates; Protein Disulfide-Isomerases; Protein Folding; Proteomics; Structure-Activity Relationship

2009
Endothelial CD146 is required for in vitro tumor-induced angiogenesis: the role of a disulfide bond in signaling and dimerization.
    The international journal of biochemistry & cell biology, 2009, Volume: 41, Issue:11

    Topics: Angiogenesis Inducing Agents; Animals; Antibodies, Monoclonal; CD146 Antigen; Cell Line, Tumor; Culture Media, Conditioned; Cysteine; Disulfides; Endothelial Cells; Epitope Mapping; Epitopes; Humans; I-kappa B Kinase; Morphogenesis; Neoplasms; Neovascularization, Pathologic; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Protein Multimerization; Signal Transduction; Structure-Activity Relationship; Up-Regulation

2009
Differential apoptotic response of human cancer cells to organoselenium compounds.
    Cancer chemotherapy and pharmacology, 2010, Volume: 66, Issue:3

    Topics: Anticarcinogenic Agents; Apoptosis; Blotting, Western; Caspase 3; Caspase 8; Caspase 9; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cysteine; Flow Cytometry; Humans; Neoplasms; Organoselenium Compounds; Selenocysteine; Selenomethionine; Sodium Selenite; Tumor Suppressor Protein p53

2010
Natural product derivative Bis(4-fluorobenzyl)trisulfide inhibits tumor growth by modification of beta-tubulin at Cys 12 and suppression of microtubule dynamics.
    Molecular cancer therapeutics, 2009, Volume: 8, Issue:12

    Topics: Animals; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Division; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cysteine; Disulfides; Dose-Response Relationship, Drug; Flow Cytometry; Fluorobenzenes; G2 Phase; HT29 Cells; Humans; Inhibitory Concentration 50; Mice; Mice, Nude; Microtubules; Molecular Structure; Neoplasms; Sulfides; Tubulin; Tumor Burden; Xenograft Model Antitumor Assays

2009
Selenium compounds activate early barriers of tumorigenesis.
    The Journal of biological chemistry, 2010, Apr-16, Volume: 285, Issue:16

    Topics: Anticarcinogenic Agents; Antioxidants; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Cellular Senescence; Cysteine; DNA Damage; DNA Repair; DNA-Binding Proteins; Histones; Humans; Male; Neoplasms; Organoselenium Compounds; Oxidative Stress; Protein Serine-Threonine Kinases; Reactive Oxygen Species; Selenium Compounds; Selenocysteine; Sodium Selenite; Tumor Suppressor Proteins

2010
p-Dimethylaminoazobenzene carcinogenesis with purified diets varying in content of cysteine, cystine, liver extract, protein, riboflavin, and other factors.
    Cancer research, 1947, Volume: 7, Issue:3

    Topics: Azo Compounds; Carcinogenesis; Cysteine; Cystine; Diet; Liver Extracts; Neoplasms; p-Dimethylaminoazobenzene; Proteins; Riboflavin

1947
PINCH1 regulates Akt1 activation and enhances radioresistance by inhibiting PP1alpha.
    The Journal of clinical investigation, 2010, Volume: 120, Issue:7

    Topics: Adaptor Proteins, Signal Transducing; Cell Adhesion; Cell Survival; Cysteine; DNA-Binding Proteins; Extracellular Matrix; Focal Adhesions; Histidine; Humans; Integrins; LIM Domain Proteins; Membrane Proteins; Neoplasms; Phosphorylation; Protein Phosphatase 1; Proto-Oncogene Proteins c-akt; Radiation Tolerance

2010
Cys-141 glutathionylation of human p53: Studies using specific polyclonal antibodies in cancer samples and cell lines.
    Free radical biology & medicine, 2010, Sep-01, Volume: 49, Issue:5

    Topics: Animals; Antibodies; Antibody Specificity; Cell Line; Cells; Cysteine; Enzyme-Linked Immunosorbent Assay; Glutathione; HCT116 Cells; HT29 Cells; Humans; Neoplasms; Oxidation-Reduction; Protein Processing, Post-Translational; Rabbits; Tumor Suppressor Protein p53

2010
Modification of cysteine 179 of IkappaBalpha kinase by nimbolide leads to down-regulation of NF-kappaB-regulated cell survival and proliferative proteins and sensitization of tumor cells to chemotherapeutic agents.
    The Journal of biological chemistry, 2010, Nov-12, Volume: 285, Issue:46

    Topics: Amino Acid Substitution; Apoptosis; Azadirachta; Blotting, Western; Caspases; Cell Proliferation; Cell Survival; Cyclin D1; Cysteine; Dose-Response Relationship, Drug; Down-Regulation; HEK293 Cells; HL-60 Cells; Humans; I-kappa B Kinase; Jurkat Cells; K562 Cells; Limonins; Molecular Structure; Neoplasms; NF-kappa B; Proto-Oncogene Proteins c-bcl-2; Tumor Necrosis Factor-alpha; U937 Cells; Vascular Endothelial Growth Factor A

2010
Comparative evaluation of glutamate-sensitive radiopharmaceuticals: Technetium-99m-glutamic acid and technetium-99m-diethylenetriaminepentaacetic acid-bis(glutamate) conjugate for tumor imaging.
    Cancer biotherapy & radiopharmaceuticals, 2010, Volume: 25, Issue:6

    Topics: Animal Structures; Animals; Carcinoma, Ehrlich Tumor; Cell Line, Tumor; Cell Survival; Cysteine; Drug Stability; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred BALB C; Molecular Structure; Neoplasms; Pentetic Acid; Rabbits; Radiopharmaceuticals; Technetium; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Whole Body Imaging

2010
S-11C-methyl-L-cysteine: a new amino acid PET tracer for cancer imaging.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2011, Volume: 52, Issue:2

    Topics: Animals; Biological Transport, Active; Cell Line, Tumor; Chromatography, High Pressure Liquid; Cysteine; Female; Isotope Labeling; Male; Mice; Mice, Inbred C57BL; Mice, Nude; Neoplasm Transplantation; Neoplasms; Positron-Emission Tomography; Proteins; Quality Control; Radioactive Tracers; Radiopharmaceuticals; Tissue Distribution; Whole Body Imaging

2011
Uptake, distribution, and speciation of selenoamino acids by human cancer cells: X-ray absorption and fluorescence methods.
    Biochemistry, 2011, Mar-15, Volume: 50, Issue:10

    Topics: Cell Line, Tumor; Cysteine; Humans; Microscopy, Fluorescence; Neoplasms; Organoselenium Compounds; Selenocysteine; Selenomethionine; X-Ray Absorption Spectroscopy

2011
Characterization of short-lived electrophilic metabolites of the anticancer agent laromustine (VNP40101M).
    Chemical research in toxicology, 2011, Apr-18, Volume: 24, Issue:4

    Topics: Acetylcysteine; Antineoplastic Agents; Carbon Isotopes; Chromatography, High Pressure Liquid; Cysteine; Glutathione; Humans; Hydrazines; Magnetic Resonance Spectroscopy; Microsomes, Liver; NADP; Neoplasms; Spectrometry, Mass, Electrospray Ionization; Sulfonamides

2011
Serum folate is significantly correlated with plasma cysteine concentrations in healthy industry workers.
    Annals of nutrition & metabolism, 2011, Volume: 58, Issue:1

    Topics: Adult; Aged; Aging; Cardiovascular Diseases; Cysteine; Extraction and Processing Industry; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Neoplasms; Norway; Risk Factors; Triglycerides; Young Adult

2011
Susceptibility of the antioxidant selenoenyzmes thioredoxin reductase and glutathione peroxidase to alkylation-mediated inhibition by anticancer acylfulvenes.
    Chemical research in toxicology, 2011, May-16, Volume: 24, Issue:5

    Topics: Agaricales; Alkylation; Antineoplastic Agents; Antioxidants; Cell Survival; Cysteine; Enzyme Inhibitors; Glutathione Peroxidase; HeLa Cells; Humans; Neoplasms; Polycyclic Sesquiterpenes; Selenocysteine; Sesquiterpenes; Spiro Compounds; Thioredoxin-Disulfide Reductase

2011
Efficient oxidation of cysteine and glutathione catalyzed by a dinuclear areneruthenium trithiolato anticancer complex.
    Inorganic chemistry, 2011, Nov-07, Volume: 50, Issue:21

    Topics: Antineoplastic Agents; Catalysis; Cysteine; Disulfides; Glutathione; Magnetic Resonance Spectroscopy; Neoplasms; Organometallic Compounds; Oxidation-Reduction; Ruthenium

2011
Strategies for optimizing the serum persistence of engineered human arginase I for cancer therapy.
    Journal of controlled release : official journal of the Controlled Release Society, 2012, Feb-28, Volume: 158, Issue:1

    Topics: Animals; Arginase; Arginine; Cysteine; Female; Humans; Mice; Mice, Inbred BALB C; Neoplasms; Polyethylene Glycols

2012
Non-invasive imaging of cysteine cathepsin activity in solid tumors using a 64Cu-labeled activity-based probe.
    PloS one, 2011, Volume: 6, Issue:11

    Topics: Animals; Cathepsins; Cell Line, Tumor; Copper Radioisotopes; Cysteine; Disease Models, Animal; Female; Humans; Mice; Molecular Probes; Neoplasms; Positron-Emission Tomography; Staining and Labeling; Tissue Distribution

2011
MUC1-C oncoprotein regulates glycolysis and pyruvate kinase M2 activity in cancer cells.
    PloS one, 2011, Volume: 6, Issue:11

    Topics: Aerobiosis; Amino Acid Sequence; Animals; Cell Line, Tumor; Cysteine; Down-Regulation; ErbB Receptors; Gene Silencing; Glycolysis; Humans; Molecular Sequence Data; Mucin-1; Mutant Proteins; Mutation; Neoplasms; Phosphorylation; Phosphotyrosine; Protein Binding; Protein Structure, Tertiary; Protein Subunits; Pyruvate Kinase; Rats

2011
Targeting cysteine-mediated dimerization of the MUC1-C oncoprotein in human cancer cells.
    International journal of oncology, 2012, Volume: 40, Issue:5

    Topics: Amino Acid Motifs; Antineoplastic Agents; Cysteine; Cytoplasm; Dimerization; Disulfides; Female; HCT116 Cells; Humans; Luminescent Proteins; Mucin-1; Mutation; Neoplasms; Oligopeptides; Oxidative Stress; Protein Binding; Protein Structure, Tertiary; Reducing Agents; Transfection

2012
Conjugation of anticancer drugs through endogenous monoclonal antibody cysteine residues.
    Methods in enzymology, 2012, Volume: 502

    Topics: Animals; Antibodies, Monoclonal; Antigens; Antineoplastic Agents; Cell Line, Tumor; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Cysteine; Disulfides; Drug Carriers; Ethylmaleimide; Humans; Hybridomas; Immobilized Proteins; Immunoconjugates; Mice; Molecular Structure; Neoplasms; Oxidation-Reduction; Sulfhydryl Reagents

2012
Selenium is a modulator of circadian clock that protects mice from the toxicity of a chemotherapeutic drug via upregulation of the core clock protein, BMAL1.
    Oncotarget, 2011, Volume: 2, Issue:12

    Topics: Animals; ARNTL Transcription Factors; Cell Line, Tumor; Circadian Clocks; CLOCK Proteins; Cyclophosphamide; Cysteine; DNA-Binding Proteins; Female; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Mice; Mice, Inbred C57BL; Neoplasms; Organoselenium Compounds; Period Circadian Proteins; Promoter Regions, Genetic; RNA Interference; RNA, Small Interfering; Selenium Compounds; Selenocysteine; Transcription Factors; Transcription, Genetic; Transcriptional Activation

2011
Preparation and evaluation of bombesin peptide derivatives as potential tumor imaging agents: effects of structure and composition of amino acid sequence on in vitro and in vivo characteristics.
    Nuclear medicine and biology, 2012, Volume: 39, Issue:6

    Topics: Amino Acid Sequence; Animals; Bombesin; Cell Line, Tumor; Cysteine; Diagnostic Imaging; Female; Humans; Mice; Neoplasms; Organotechnetium Compounds; Protein Transport; Receptors, Bombesin

2012
Metabolite profiling of bendamustine in urine of cancer patients after administration of [14C]bendamustine.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Bendamustine Hydrochloride; Carbon Radioisotopes; Creatinine; Cysteine; Dealkylation; Humans; Hydrolysis; Hydroxylation; Metabolic Networks and Pathways; Metabolome; Neoplasms; Nitrogen Mustard Compounds; Oxidation-Reduction; Phosphates; Uric Acid

2012
Enhanced preclinical efficacy of tamoxifen developed as alginate-cysteine/disulfide bond reduced albumin nanoparticles.
    International journal of pharmaceutics, 2012, Oct-15, Volume: 436, Issue:1-2

    Topics: Alginates; Animals; Antineoplastic Agents, Hormonal; Cell Line, Tumor; Cysteine; Disulfides; Female; Glucuronic Acid; Hexuronic Acids; Humans; Mice; Mice, Nude; Nanoparticles; Neoplasms; Ovary; Serum Albumin, Bovine; Tamoxifen; Tumor Burden; Uterus; Xenograft Model Antitumor Assays

2012
Inactivation of the glutamine/amino acid transporter ASCT2 by 1,2,3-dithiazoles: proteoliposomes as a tool to gain insights in the molecular mechanism of action and of antitumor activity.
    Toxicology and applied pharmacology, 2012, Nov-15, Volume: 265, Issue:1

    Topics: Amino Acid Transport System ASC; Amino Acid Transport Systems; Animals; Antineoplastic Agents; Binding Sites; Computer Simulation; Cysteine; Dose-Response Relationship, Drug; Glutamine; Kinetics; Minor Histocompatibility Antigens; Neoplasms; Proteolipids; Rats; Structure-Activity Relationship; Thiazoles

2012
Blood-stable, tumor-adaptable disulfide bonded mPEG-(Cys)4-PDLLA micelles for chemotherapy.
    Biomaterials, 2013, Volume: 34, Issue:2

    Topics: Animals; Antibiotics, Antineoplastic; Cysteine; Delayed-Action Preparations; Doxorubicin; Lactic Acid; Male; Mice; Mice, Inbred BALB C; Micelles; Neoplasms; Polyesters; Polyethylene Glycols; Polymers

2013
Selenium for prevention: eating your way to better DNA repair?
    Journal of the National Cancer Institute, 2003, Jan-15, Volume: 95, Issue:2

    Topics: Antioxidants; Cysteine; DNA Repair; Feeding Behavior; Humans; Neoplasms; Nuts; Organoselenium Compounds; Randomized Controlled Trials as Topic; Selenium Compounds; Selenomethionine; Tumor Suppressor Protein p53; United States

2003
A novel form of the plasminogen activator inhibitor created by cysteine mutations extends its half-life: relevance to cancer and angiogenesis.
    Molecular cancer therapeutics, 2003, Volume: 2, Issue:1

    Topics: Amino Acid Sequence; Amino Acid Substitution; Base Sequence; Binding Sites; Cysteine; DNA Primers; Endothelium, Vascular; Half-Life; Humans; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Neoplasms; Neovascularization, Pathologic; Plasminogen Activator Inhibitor 1; Polymerase Chain Reaction; Protein Conformation; Protein Structure, Secondary; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Urokinase-Type Plasminogen Activator

2003
Synthesis and phorbol ester binding of the cysteine-rich domains of diacylglycerol kinase (DGK) isozymes. DGKgamma and DGKbeta are new targets of tumor-promoting phorbol esters.
    The Journal of biological chemistry, 2003, May-16, Volume: 278, Issue:20

    Topics: Amino Acid Sequence; Animals; Binding, Competitive; Chromatography, High Pressure Liquid; Cricetinae; Cysteine; Diacylglycerol Kinase; Gene Deletion; Green Fluorescent Proteins; Humans; Kinetics; Luminescent Proteins; Molecular Sequence Data; Mutation; Neoplasms; Peptides; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Binding; Protein Conformation; Protein Folding; Protein Isoforms; Protein Structure, Tertiary; Protein Transport; Rats; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine; Time Factors

2003
Modulation of plasma thiols and mixed disulfides by BNP7787 in patients receiving paclitaxel/cisplatin therapy.
    Cancer chemotherapy and pharmacology, 2003, Volume: 51, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chromatography, High Pressure Liquid; Cisplatin; Cysteine; Disulfides; Glutathione; Half-Life; Humans; Infusions, Intravenous; Kinetics; Mesna; Neoplasms; Paclitaxel; Sulfhydryl Compounds

2003
Growth of tumor fragments X-radiated in vitro following pretreatment with cysteine.
    Cancer research, 1952, Volume: 12, Issue:11

    Topics: Animals; Cysteine; Humans; In Vitro Techniques; Neoplasms; Neoplasms, Experimental; X-Rays

1952
[Unusual effects of administration of sodium thiosulfate or of cysteine on the clinical picture and metabolism of subjects with diffuse neoplasms].
    Minerva medica, 1953, Jan-06, Volume: 44, Issue:1-2

    Topics: Cysteine; Humans; Neoplasms; Thiosulfates

1953
[The presence of an organic transsulfurase in normal and in neoplastic tissues].
    Bollettino della Societa italiana di biologia sperimentale, 1953, Volume: 29, Issue:1

    Topics: Biochemical Phenomena; Cysteine; Cystine; Enzymes; Health Services; Neoplasms; Sulfurtransferases; Thiocyanates

1953
Studies on analogues of L-cysteine and L-cystine. II. The effect of selenium cystine on Murphy lymphosarcoma tumor cells in the rat.
    Blood, 1956, Volume: 11, Issue:1

    Topics: Animals; Cysteine; Cystine; Lymphoma; Lymphoma, Non-Hodgkin; Neoplasms; Neoplasms, Experimental; Rats; Selenium

1956
Cystine-cysteine concentration in homogenate and cell fractions of rat liver during azo dye feeding and regeneration and in rat liver tumor.
    Revue canadienne de biologie, 1955, Volume: 14, Issue:3

    Topics: Animals; Azo Compounds; Cysteine; Cystine; Liver; Neoplasms; Organic Chemicals; Rats; Regeneration

1955
Mode of action of alkylating agents: formation of S-ethylcysteine from ethyl methanesulphonate in vivo.
    Nature, 1957, Jun-08, Volume: 179, Issue:4571

    Topics: Alkylating Agents; Antineoplastic Agents; Cysteine; Ethyl Methanesulfonate; Humans; Neoplasms

1957
[Influence of heavy metal ions on mouse Ehrlich ascites carcinoma cells and the action of cystein].
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1961, May-03, Volume: 323

    Topics: Ascites; Cysteine; Ions; Metabolism; Metals; Metals, Heavy; Neoplasms

1961
Comparative study of the cystine-cysteine content of the mucoprotein of normal, silicotic and cancerous sera.
    Clinica chimica acta; international journal of clinical chemistry, 1962, Volume: 7

    Topics: Cysteine; Cystine; Hematologic Diseases; Humans; Mucoproteins; Neoplasms; Oxidation-Reduction; Silicosis

1962
[THE EFFECT OF LEYK (CYSTEINE DERIVATIVE) ON THE RADIATION INJURY].
    Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1963, Volume: 23

    Topics: Anemia; Animals; Blood Cell Count; Cysteine; Neoplasms; Pharmacology; Rabbits; Radiation Injuries; Radiation-Protective Agents; Research; Thiazolidines

1963
STUDIES OF THE MODE OF ACTION OF TUMOUR-GROWTH-INHIBITING ALKYLATING AGENTS. IV. IN-VITRO REACTIONS OF 2-CHLOROETHYLARYLAMINES.
    Biochemical pharmacology, 1963, Volume: 12

    Topics: Alkylating Agents; Chemistry, Pharmaceutical; Cysteine; Glutathione; Neoplasms; Nitrogen Mustard Compounds; Research

1963
PLASMA FIBRIN STABILIZING FACTOR ACTIVITY IN VARIOUS DISEASES.
    Blood, 1964, Volume: 23

    Topics: Alpha-Globulins; Anemia; Biological Assay; Biomedical Research; Blood Coagulation; Blood Coagulation Factors; Calcium; Collagen Diseases; Cysteine; Factor XIII; Fibrin; Hemorrhagic Disorders; Humans; Leukemia; Liver; Liver Diseases; Lymphoma; Neoplasms; Pathology; Serum Globulins; Sulfhydryl Compounds; Thrombin

1964
STUDIES ON ANTITUMOR ACTION OF ANTIMONY-COMPLEXONES.
    Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20

    Topics: Animals; Antimony; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cysteine; Metabolism; Mice; Neoplasms; Neoplasms, Experimental; Pharmacology; Research; Sarcoma 180; Sarcoma, Experimental; Sulfhydryl Compounds; Zinc Isotopes

1964
[STUDIES ON ANTITUMOR DRUGS. V. A STUDY ON CERTAIN COMBINATIONS OF ANTITUMOR AGENTS].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1963, Volume: 10

    Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Cysteine; Diethylstilbestrol; Mechlorethamine; Mercaptopurine; Mice; Neoplasms; Pharmacology; Research; Sarcoma; Sarcoma 180; Sarcoma, Experimental

1963
[EFFECT OF HEPARIN ON MALIGNANT TUMOR CELLS IN TISSUE CULTURE].
    Biulleten' eksperimental'noi biologii i meditsiny, 1964, Volume: 57

    Topics: Acid Phosphatase; Alkaline Phosphatase; Cysteine; Electron Transport Complex II; Electron Transport Complex IV; Esterases; Glutathione; Hemangiosarcoma; Heparin; Lipase; Neoplasms; Neoplasms, Experimental; Pharmacology; Research; Research Design; Succinate Dehydrogenase; Tissue Culture Techniques

1964
BIOLOGICALLY ACTIVE DNA FROM CANINE LYMPHOMA CELLS.
    Nature, 1964, May-09, Volume: 202

    Topics: Animals; Cysteine; DNA; DNA, Neoplasm; Dogs; Leukemia; Leukemia, Experimental; Lymph Nodes; Lymphoma; Neoplasms; Neoplasms, Experimental; Pathology; Pharmacology; Research; Spleen

1964
POLAROGRAPHIC REACTIONS OF PLASMA PROTEINS AND THEIR CLINICAL SIGNIFICANCE.
    Clinical chemistry, 1965, Volume: 11

    Topics: Alcohols; Animals; Arthritis; Benz(a)Anthracenes; Blood Proteins; Clinical Laboratory Techniques; Cobalt; Cysteine; Cystine; Dogs; Ethanol; Haplorhini; Laboratories; Neoplasms; Polarography; Research; Toxicology

1965
REACTION OF THE CARCINOGEN DIMETHYLNITROSAMINE WITH PROTEINS AND WITH THIOL COMPOUNDS IN THE INTACT ANIMAL.
    The Biochemical journal, 1965, Volume: 94

    Topics: Alkylation; Animals; Carcinogens; Chromatography; Cysteine; Dimethylnitrosamine; Formates; Ion Exchange Resins; Liver; Neoplasms; Nitrosamines; Pharmacology; Proteins; Rats; Research; Silver; Sulfhydryl Compounds; Toxicology; Urine

1965
S-Carbamylcysteine inhibition of protein synthesis by Ehrlich ascites tumor cells.
    Journal of the National Cancer Institute, 1962, Volume: 28

    Topics: Animals; Carcinoma, Ehrlich Tumor; Cysteine; Glutamine; Humans; Neoplasms; Protein Biosynthesis; Proteins

1962
Covalent disulfide-linked anti-CEA diabody allows site-specific conjugation and radiolabeling for tumor targeting applications.
    Protein engineering, design & selection : PEDS, 2004, Volume: 17, Issue:1

    Topics: Animals; Antibodies; Base Sequence; Binding, Competitive; Carcinoembryonic Antigen; Cysteine; Dimerization; Disulfides; Electrophoresis, Polyacrylamide Gel; Female; Mice; Mice, Nude; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Neoplasm Transplantation; Neoplasms; Peptides; Protein Structure, Tertiary; Sulfhydryl Compounds; Time Factors; Tomography, Emission-Computed

2004
Selective modulation of the therapeutic efficacy of anticancer drugs by selenium containing compounds against human tumor xenografts.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Apr-01, Volume: 10, Issue:7

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Camptothecin; Carcinoma, Squamous Cell; Cell Line, Tumor; Colonic Neoplasms; Cysteine; Dose-Response Relationship, Drug; Drug Synergism; Female; Humans; Irinotecan; Maximum Tolerated Dose; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms; Organoselenium Compounds; Radiation-Sensitizing Agents; Selenium; Selenocysteine; Selenomethionine; Time Factors

2004
Solid state and solution studies of a vanadium(III)-L-cysteine compound and demonstration of its antimetastatic, antioxidant and inhibition of neutral endopeptidase activities.
    Journal of inorganic biochemistry, 2004, Volume: 98, Issue:6

    Topics: Animals; Antineoplastic Agents; Antioxidants; Cysteine; Molecular Structure; Neoplasms; Neprilysin; Oxidation-Reduction; Rats; Rats, Wistar; Structure-Activity Relationship; Vanadates

2004
Pteroyl-gamma-glutamate-cysteine synthesis and its application in folate receptor-mediated cancer cell targeting using folate-tethered liposomes.
    Analytical biochemistry, 2004, Sep-01, Volume: 332, Issue:1

    Topics: Caco-2 Cells; Carrier Proteins; Chromatography, High Pressure Liquid; Cysteine; Doxorubicin; Fluoresceins; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Liposomes; Neoplasms; Phosphatidylethanolamines; Polyethylene Glycols; Receptors, Cell Surface

2004
Thioredoxin modulates activator protein 1 (AP-1) activity and p27Kip1 degradation through direct interaction with Jab1.
    Oncogene, 2004, Nov-25, Volume: 23, Issue:55

    Topics: Binding Sites; Cell Cycle Proteins; Cell Line; Cell Proliferation; COP9 Signalosome Complex; Cyclin-Dependent Kinase Inhibitor p27; Cysteine; Disease Progression; Disulfides; DNA-Binding Proteins; DNA, Complementary; Fluorescence Resonance Energy Transfer; Gene Expression Regulation; Genes, Reporter; Glutathione Transferase; HeLa Cells; Humans; Immunoprecipitation; Intracellular Signaling Peptides and Proteins; Mutation; Neoplasms; Oligonucleotides, Antisense; Oxidation-Reduction; Peptide Hydrolases; Prognosis; Protein Binding; Recombinant Proteins; Signal Transduction; Thioredoxins; Time Factors; Transcription Factor AP-1; Transcription Factors; Transcriptional Activation; Tumor Suppressor Proteins; Two-Hybrid System Techniques

2004
Redox-sensitive signaling factors and antioxidants: how tumor cells respond to ionizing radiation.
    The Journal of nutrition, 2004, Volume: 134, Issue:11

    Topics: Antioxidants; Cysteine; DNA Damage; Free Radicals; Humans; Hydrogen Peroxide; Neoplasms; Oxidation-Reduction; Oxidative Stress; Radiation, Ionizing; Signal Transduction; Thioredoxin-Disulfide Reductase; Thioredoxins

2004
Human Kruppel-like factor 5 is a target of the E3 ubiquitin ligase WWP1 for proteolysis in epithelial cells.
    The Journal of biological chemistry, 2005, Dec-16, Volume: 280, Issue:50

    Topics: Amino Acid Motifs; Blotting, Western; Breast Neoplasms; Catalysis; Cell Line, Tumor; Cysteine; DNA; Epithelial Cells; Female; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Glutathione Transferase; Humans; Immunoprecipitation; Kruppel-Like Transcription Factors; Luciferases; Male; Microscopy, Confocal; Microscopy, Fluorescence; Neoplasms; Plasmids; Prostatic Neoplasms; Proteasome Endopeptidase Complex; Protein Binding; Protein Biosynthesis; Protein Structure, Tertiary; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Small Interfering; Time Factors; Transcriptional Activation; Transfection; Ubiquitin; Ubiquitin-Protein Ligases

2005
Dietary Factors in the Utilization of Homocystine.
    Proceedings of the National Academy of Sciences of the United States of America, 1948, Volume: 34, Issue:3

    Topics: Cysteine; Cystine; Diet; Ear Neoplasms; Homocystine; Humans; Neoplasms

1948
A novel anticancer effect of garlic derivatives: inhibition of cancer cell invasion through restoration of E-cadherin expression.
    Carcinogenesis, 2006, Volume: 27, Issue:11

    Topics: Antineoplastic Agents; Cadherins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Collagen; Cysteine; Drug Combinations; Drug Design; Garlic; Humans; Inhibitory Concentration 50; Laminin; Neoplasm Invasiveness; Neoplasms; Proteoglycans

2006
Cancer-associated mutations in the MDM2 zinc finger domain disrupt ribosomal protein interaction and attenuate MDM2-induced p53 degradation.
    Molecular and cellular biology, 2007, Volume: 27, Issue:3

    Topics: Active Transport, Cell Nucleus; Amino Acid Sequence; Animals; Cell Nucleus; Cysteine; HeLa Cells; Humans; Mice; Molecular Sequence Data; Mutant Proteins; Mutation; Neoplasms; Phenylalanine; Protein Binding; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-mdm2; Ribosomal Proteins; Transcription, Genetic; Tumor Suppressor Protein p53; Ubiquitin; Zinc Fingers

2007
Caspase-2 deficiency enhances aging-related traits in mice.
    Mechanisms of ageing and development, 2007, Volume: 128, Issue:2

    Topics: Adipose Tissue; Aging; Animals; Apoptosis; Bone Density; Bone Resorption; Caspase 2; Cysteine; Hair; Liver; Longevity; Mice; Mice, Knockout; Neoplasms; Oxidative Stress; Proteins; Survival Rate

2007
Efficacy of increasing the therapeutic index of irinotecan, plasma and tissue selenium concentrations is methylselenocysteine dose dependent.
    Biochemical pharmacology, 2007, May-01, Volume: 73, Issue:9

    Topics: Administration, Oral; Animals; Bone Marrow; Camptothecin; Cysteine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Irinotecan; Kidney; Kinetics; Liver; Mice; Mice, Nude; Neoplasms; Organoselenium Compounds; Plasma; Selenium; Selenocysteine

2007
Hyperhomocysteinaemia and immune activation in patients with cancer.
    Clinical chemistry and laboratory medicine, 2007, Volume: 45, Issue:1

    Topics: Aged; Biomarkers; Case-Control Studies; Cysteine; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Immune System; Male; Neoplasms; Neopterin; Vitamin B 12

2007
Metabolism of glutathione in tumour cells as evidenced by 1H MRS.
    FEBS letters, 2007, Feb-20, Volume: 581, Issue:4

    Topics: Buthionine Sulfoximine; Cell Line, Tumor; Cysteine; Glutamic Acid; Glutathione; Humans; Magnetic Resonance Spectroscopy; Neoplasms; Protons; Time Factors

2007
99mTc-labelled HYNIC-minigastrin with reduced kidney uptake for targeting of CCK-2 receptor-positive tumours.
    European journal of nuclear medicine and molecular imaging, 2007, Volume: 34, Issue:8

    Topics: Animals; Carcinoma, Medullary; Cysteine; Edetic Acid; Gastrins; Gene Expression Regulation, Neoplastic; Glycine; Humans; Kidney; Liver; Neoplasms; Organotechnetium Compounds; Radionuclide Imaging; Rats; Receptor, Cholecystokinin B; Technetium; Thyroid Neoplasms; Tissue Distribution

2007
Polymorphism of dihydropyrimidine dehydrogenase (DPYD) Cys29Arg and risk of six malignancies in Japanese.
    Nagoya journal of medical science, 2005, Volume: 67, Issue:3-4

    Topics: Adult; Aged; Aged, 80 and over; Arginine; Asian People; Chi-Square Distribution; Cysteine; Dihydrouracil Dehydrogenase (NADP); Female; Gene Frequency; Genotype; Humans; Japan; Male; Middle Aged; Models, Biological; Neoplasms; Odds Ratio; Polymorphism, Genetic

2005
Evidence for the rapid conversion of stephacidin B into the electrophilic monomer avrainvillamide in cell culture.
    Journal of the American Chemical Society, 2007, Apr-25, Volume: 129, Issue:16

    Topics: Cell Proliferation; Cysteine; Humans; Indole Alkaloids; Indoles; Neoplasm Proteins; Neoplasms; Tumor Cells, Cultured

2007
Regulation of HIF-1alpha stability through S-nitrosylation.
    Molecular cell, 2007, Apr-13, Volume: 26, Issue:1

    Topics: Amino Acid Sequence; Animals; Cell Line, Tumor; Cells, Cultured; Cysteine; Gene Expression Regulation, Neoplastic; Hypoxia-Inducible Factor 1, alpha Subunit; Macrophages; Mice; Models, Biological; Molecular Sequence Data; Mutation; Neoplasms; Nitric Oxide; Nitric Oxide Synthase Type II; Sequence Homology, Amino Acid; Transfection

2007
Structural insight into the dual ligand specificity and mode of high density lipoprotein association of apolipoprotein D.
    The Journal of biological chemistry, 2007, Oct-19, Volume: 282, Issue:42

    Topics: Apolipoprotein A-II; Apolipoproteins D; Arachidonic Acid; Binding Sites; Crystallography, X-Ray; Cysteine; Disulfides; Humans; Hydrophobic and Hydrophilic Interactions; Ligands; Lipid Metabolism; Lipoproteins, HDL; Neoplasms; Nervous System Diseases; Progesterone; Protein Binding; Protein Structure, Secondary; Structure-Activity Relationship; Substrate Specificity

2007
The extracolonic cancer spectrum in females with the common 'South African' hMLH1 c.C1528T mutation.
    Familial cancer, 2008, Volume: 7, Issue:3

    Topics: Adaptor Proteins, Signal Transducing; Adult; Alleles; Case-Control Studies; Cohort Studies; Colorectal Neoplasms, Hereditary Nonpolyposis; Cysteine; Female; Genetic Predisposition to Disease; Humans; Incidence; Microsatellite Instability; Middle Aged; Mutation; MutL Protein Homolog 1; Neoplasms; Neoplasms, Multiple Primary; Nuclear Proteins; Phenotype; Population Surveillance; Risk Factors; Sex Factors; Siblings; South Africa; Threonine

2008
Redox regulation of the protein tyrosine phosphatase PTP1B in cancer cells.
    The FEBS journal, 2008, Volume: 275, Issue:1

    Topics: Amino Acid Sequence; Animals; Cell Line, Tumor; Cysteine; HeLa Cells; Humans; Mass Spectrometry; Mice; Molecular Sequence Data; Neoplasms; NIH 3T3 Cells; Oxidation-Reduction; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Reactive Oxygen Species; Tyrosine

2008
Evaluation of maleimide derivative of DOTA for site-specific labeling of recombinant affibody molecules.
    Bioconjugate chemistry, 2008, Volume: 19, Issue:1

    Topics: Animals; Binding Sites; Chelating Agents; Cysteine; Heterocyclic Compounds, 1-Ring; Histidine; Indium Radioisotopes; Maleimides; Mice; Mice, Inbred BALB C; Neoplasms; Peptides; Radionuclide Imaging; Receptor, ErbB-2; Recombinant Fusion Proteins; Sensitivity and Specificity; Transplantation, Heterologous

2008
Inhibiting wild-type and C299S mutant AKR1B10; a homologue of aldose reductase upregulated in cancers.
    European journal of pharmacology, 2008, Apr-28, Volume: 584, Issue:2-3

    Topics: Aldehyde Reductase; Aldo-Keto Reductases; Antibiotics, Antineoplastic; Antineoplastic Agents; Benzothiazoles; Clofibric Acid; Cysteine; Daunorubicin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glyceraldehyde; Humans; Imidazolidines; Kinetics; Mutation; Neoplasms; Oxidation-Reduction; Phthalazines; Pyrimidines; Recombinant Proteins; Serine

2008
Phase I and pharmacologic evaluation of nafazatrom in patients with cancer.
    Investigational new drugs, 1984, Volume: 2, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Chromatography, High Pressure Liquid; Cysteine; Drug Evaluation; Female; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Neoplasms; Pyrazoles; Pyrazolones

1984
Modulation of plasma cyst(e)ine by cisplatin.
    European journal of cancer & clinical oncology, 1983, Volume: 19, Issue:7

    Topics: Cell Division; Chromatography, High Pressure Liquid; Cisplatin; Cysteine; Humans; Leukemia, Myeloid, Acute; Neoplasms; Time Factors

1983
[Methods of serum enzyme determination and its clinical significance: cystine aminopeptidase].
    Rinsho byori. The Japanese journal of clinical pathology, 1983, Volume: Suppl 55

    Topics: Aminopeptidases; Cysteine; Cystinyl Aminopeptidase; Female; Fetal Monitoring; Humans; Male; Methods; Neoplasms; Placental Function Tests; Pregnancy; Substrate Specificity

1983
High-performance liquid chromatographic determination of nafazatrom in human plasma using fluorescence detection.
    Journal of chromatography, 1984, Jan-13, Volume: 305, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cysteine; Drug Stability; Humans; Hydrogen-Ion Concentration; Neoplasms; Pyrazoles; Pyrazolones; Spectrometry, Fluorescence; Time Factors

1984
Targeting c-erbB-2 expressing tumors using single-chain Fv monomers and dimers.
    Cancer research, 1995, Dec-01, Volume: 55, Issue:23 Suppl

    Topics: Amino Acid Sequence; Animals; Cysteine; Escherichia coli; Humans; Immunoglobulin Fragments; Iodine Radioisotopes; Mice; Mice, Nude; Molecular Sequence Data; Neoplasms; Protein Folding; Radionuclide Imaging; Receptor, ErbB-2; Recombinant Proteins; Tissue Distribution; Transplantation, Heterologous

1995
Diallyl disulfide inhibits the proliferation of human tumor cells in culture.
    Biochimica et biophysica acta, 1996, Jan-17, Volume: 1315, Issue:1

    Topics: Allyl Compounds; Antineoplastic Agents; Calcium; Calcium-Transporting ATPases; Cell Division; Cysteine; Disulfides; Egtazic Acid; Ethylmaleimide; Garlic; Humans; Kinetics; Molecular Structure; Neoplasms; Plants, Medicinal; Tumor Cells, Cultured

1996
Cell-cycle specific cytotoxicity mediated by rearranged ent-kaurene diterpenoids isolated from Parinari curatellifolia.
    Chemico-biological interactions, 1996, Jan-05, Volume: 99, Issue:1-3

    Topics: Africa; Cell Cycle; Cell Division; Cell Line; Cysteine; Diterpenes; Flow Cytometry; G2 Phase; Humans; Magnetic Resonance Spectroscopy; Medicine, Traditional; Mercaptoethanol; Molecular Structure; Neoplasms; Plants; Spectrum Analysis

1996
Activity and distribution of the cysteine prodrug activating enzyme, 5-oxo-L-prolinase, in human normal and tumor tissues.
    Cancer letters, 1997, Jul-15, Volume: 117, Issue:1

    Topics: Cysteine; Humans; Neoplasms; Prodrugs; Pyroglutamate Hydrolase; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines

1997
The stinking rose: organosulfur compounds and cancer.
    The American journal of clinical nutrition, 1997, Volume: 66, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Cell Division; Cysteine; Garlic; Humans; Neoplasms; Plants, Medicinal

1997
Elevation of homocysteine and excitatory amino acid neurotransmitters in the CSF of children who receive methotrexate for the treatment of cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:8

    Topics: Antimetabolites, Antineoplastic; Central Nervous System; Child; Chromatography, High Pressure Liquid; Cysteine; Excitatory Amino Acids; Homocysteine; Humans; Methotrexate; Neoplasms; Neurotransmitter Agents; Retrospective Studies

1997
Molecular cloning of Frizzled-10, a novel member of the Frizzled gene family.
    Biochemical and biophysical research communications, 1999, Aug-19, Volume: 262, Issue:1

    Topics: Adult; Amino Acid Sequence; Cerebellum; Chromosomes, Human, Pair 12; Cloning, Molecular; Cysteine; DNA, Complementary; Female; Frizzled Receptors; Gene Expression; Genomic Library; Humans; Kidney; Lung; Molecular Sequence Data; Multigene Family; Neoplasms; Phylogeny; Placenta; Receptors, Cell Surface; Receptors, G-Protein-Coupled; RNA, Messenger; Sequence Homology, Amino Acid; Tumor Cells, Cultured

1999
Blockage of drug resistance in vitro by disulfiram, a drug used to treat alcoholism.
    Journal of the National Cancer Institute, 2000, Jun-07, Volume: 92, Issue:11

    Topics: Adenosine Triphosphatases; Alcohol Deterrents; Aldehyde Dehydrogenase; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cysteine; Disulfiram; DNA, Complementary; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Kidney; Neoplasms; Transfection; Tumor Cells, Cultured

2000
Synthesis of hybrid distamycin-cysteine labeled with 99mTc: a model for a novel class of cancer imaging agents.
    Bioorganic & medicinal chemistry letters, 2000, Jun-19, Volume: 10, Issue:12

    Topics: Cysteine; Distamycins; Humans; Neoplasms; Organotechnetium Compounds; Radionuclide Imaging; Radiopharmaceuticals

2000
MMP-28, a new human matrix metalloproteinase with an unusual cysteine-switch sequence is widely expressed in tumors.
    Gene, 2001, Mar-07, Volume: 265, Issue:1-2

    Topics: Alternative Splicing; Amino Acid Motifs; Amino Acid Sequence; Chromosome Mapping; Chromosomes, Human, Pair 17; Cloning, Molecular; Cysteine; DNA, Complementary; Evolution, Molecular; Exons; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genes; Humans; Introns; Male; Matrix Metalloproteinases; Matrix Metalloproteinases, Secreted; Molecular Sequence Data; Neoplasms; Phylogeny; Sequence Alignment; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Tissue Distribution

2001
The metabolism of sulphur in relation to the biochemistry of cystine and cysteine: its fundamental importance in biology. A cyclic interchange between their mono- and di-sulphides is the unique reaction creating life and intelligence.
    Medical hypotheses, 2001, Volume: 56, Issue:5

    Topics: Cysteine; Cystine; Humans; Neoplasms; Sulfides; Sulfur

2001
The K(m) for Radiosensitization of Human Tumor Cells by Oxygen is Much Greater than 3 mmHg and is Further Increased by Elevated Levels of Cysteine.
    Radiation research, 2001, Volume: 156, Issue:4

    Topics: Cell Survival; Cysteine; Glutathione; Humans; Neoplasms; Oxygen; Radiation Tolerance; Tumor Cells, Cultured

2001
The utility of (99m)Tc-DMSA and Tc(99m)-EC scintigraphy for early diagnosis of ifosfamide induced nephrotoxicity.
    Nuclear medicine communications, 2001, Volume: 22, Issue:12

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; beta 2-Microglobulin; Biological Transport; Child; Child, Preschool; Cisplatin; Creatinine; Cysteine; Female; Humans; Ifosfamide; Infant; Kidney; Male; Neoplasms; Organotechnetium Compounds; Radionuclide Imaging; Radiopharmaceuticals; Technetium Tc 99m Dimercaptosuccinic Acid; Tissue Distribution

2001
Metronidazole (Flagyl), misonidazole (Ro 07-0582), iron, zinc and sulphur compounds in cancer therapy.
    The British journal of cancer. Supplement, 1978, Volume: 3

    Topics: Cysteamine; Cysteine; Ferrous Compounds; Glutathione; Kinetics; Metronidazole; Neoplasms; Nitroimidazoles; Oxidation-Reduction; Zinc

1978
Metronidazole (Flagyl): iron catalysed reaction with sulphydryl groups and tumour radiosensitisation.
    Nature, 1975, Jun-05, Volume: 255, Issue:5508

    Topics: Animals; Catalysis; Cysteine; Iron; Kinetics; Metronidazole; Mice; Neoplasms; Radiation-Sensitizing Agents; Radiotherapy Dosage; Sulfhydryl Compounds

1975
[Anticancer therapy with amino acid imbalance].
    Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49 Suppl

    Topics: Amino Acids; Animals; Antineoplastic Agents; Arginine; Cysteine; Humans; Methionine; Neoplasms; Parenteral Nutrition, Total; Phenylalanine; Tyrosine; Valine

1991
Transforming growth factor alpha-Pseudomonas exotoxin fusion protein prolongs survival of nude mice bearing tumor xenografts.
    Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:12

    Topics: ADP Ribose Transferases; Alanine; Animals; Antineoplastic Agents; Bacterial Toxins; Cell Line; Cloning, Molecular; Cysteine; ErbB Receptors; Exotoxins; Female; Humans; Mice; Mice, Nude; Mutation; Neoplasm Transplantation; Neoplasms; Pseudomonas aeruginosa Exotoxin A; Recombinant Fusion Proteins; Transforming Growth Factor alpha; Transforming Growth Factors; Virulence Factors

1990
[Use of cysteine preparations in radiotherapy of malignant tumor].
    Rinsho hoshasen. Clinical radiography, 1974, Volume: 19, Issue:5

    Topics: Cysteine; Drug Combinations; Female; Glucose; Humans; Male; Neoplasms; Radiation-Protective Agents

1974
Collagenolytic enzymes in human neoplasms.
    Cancer research, 1972, Volume: 32, Issue:5

    Topics: Acrylamides; Adenocarcinoma; Blood; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Collagen; Colonic Neoplasms; Cysteine; Edetic Acid; Electrophoresis; Endopeptidases; Female; Humans; Neoplasms; Organ Culture Techniques; Protease Inhibitors; Uterine Neoplasms

1972
[Is there any experimental evidence for the application of radioprotective substances in radiotherapy?].
    Archiv fur Geschwulstforschung, 1971, Volume: 37, Issue:3

    Topics: Animals; Body Burden; Cysteine; Evaluation Studies as Topic; Mice; Neoplasms; Neoplasms, Experimental; Radiation Injuries; Radiation Monitoring; Radiation-Protective Agents; Radioisotope Dilution Technique; Radiometry; Radiotherapy

1971
[The "reequilibration" test and its use in the treatment of certain forms of cancer and other afflictions].
    Journal of chromatography, 1966, Volume: 25, Issue:1

    Topics: Adenosine Triphosphate; Asparagine; Betaine; Choline; Creatine; Cysteine; Deficiency Diseases; Electrophoresis; Elements; Glutamates; Histidine; Humans; Metabolic Diseases; Methionine; Neoplasms; Quaternary Ammonium Compounds

1966