cysteine has been researched along with Melanoma in 78 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 30 (38.46) | 18.7374 |
1990's | 15 (19.23) | 18.2507 |
2000's | 18 (23.08) | 29.6817 |
2010's | 10 (12.82) | 24.3611 |
2020's | 5 (6.41) | 2.80 |
Authors | Studies |
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Kiniwa, Y; Meling, MT; Ogawa, E; Okuyama, R; Sato, Y | 1 |
Ji, G; Luo, B; Shen, G; Tian, T | 1 |
Ahmad, H; Baer, RW; Cox, JL; Crotts, MS; Jacobs, JC | 1 |
Janik, K; Jurkowska, H; Rydz, L; Wróbel, M | 1 |
Anslyn, EV; Cano, M; Dalby, KN; Ebelt, ND; Edupuganti, R; Ghose, R; Harger, M; Johnson, WH; Kaoud, TS; Park, J; Piserchio, A; Pridgen, JR; Radwan, MF; Ren, P; Sammons, R; Tavares, CDJ; Tsai, KY; Van Ravenstein, SX; Warthaka, M; Zamora-Olivares, D | 1 |
Bird, JT; Byrum, SD; Miousse, IR; Morehead, LC; Wallis, KF | 1 |
Chan, TA; Chinnaiyan, A; Choi, JE; Cieslik, M; Georgiou, G; Gijón, M; Green, M; Gu, W; Johnson, JK; Kennedy, PD; Kryczek, I; Lamb, C; Lang, X; Lawrence, TS; Li, G; Li, J; Li, W; Liao, P; Liu, R; Sell, A; Stone, E; Szeliga, W; Tanno, Y; Vatan, L; Wang, W; Wei, S; Xia, H; Zhang, H; Zhou, J; Zou, W | 1 |
Conner, S; He, J; Li, G; McCarthy, JB; Price, MA; Sachs, J; Turley, EA; Wanshura, LEC; Welch, DR; Yang, J; Yi, M | 1 |
Chen, W; Chen, Z; Guan, X; Jiang, Z; Lin, N; Zhang, X; Zheng, Z | 1 |
Chen, W; Feng, J; Jiang, Z; Ling, Y; Zhang, X | 1 |
Maesawa, C; Nishiya, M; Shibazaki, M; Yasuhira, S | 1 |
Gangapurkar, B; Jariwalla, RJ; Nakamura, D | 1 |
Barth, PJ; Moll, I; Nowak, K; Wessel, C; Westhoff, CC | 1 |
Anichini, A; Bersani, I; Millo, E; Mingari, MC; Molla, A; Moretta, L; Nicolini, G; Pietra, G; Sensi, M; Vegetti, C; Weiss, E | 1 |
Boucher, KM; Cassidy, P; Cotter, MA; Florell, SR; Goodson, AG; Grossman, D; Liu, T; Wade, M | 1 |
Castellani, P; Ciriolo, MR; Delfino, L; Lucibello, M; Rubartelli, A; Venè, R | 1 |
Haase-Kohn, C; Lenk, J; Pietzsch, J; Wolf, S | 1 |
Benson, MD; Berthiaume, LG; Bui, M; Ellgaard, L; Lynes, EM; Schneider, B; Simmen, T; Yap, MC | 1 |
Jeong, J; Kim, Y; Kyung Seong, J; Lee, KJ | 1 |
Arano, Y; Garcia Flores, L; Jinnouchi, S; Kataoka, H; Kawai, K; Nagamachi, S; Nishii, R; Tamura, S | 1 |
Dubois, J; Duez, P; Ghanem, G; Kinnaert, E; Morandini, R; Van Houtte, P | 1 |
Cascante, M; Centelles, JJ; Jimenez, A; Julià, L; Lozano, C; Torres, JL | 1 |
Boyle, GM; Fairlie, DP; Lucke, AJ; Parsons, PG | 1 |
Berrevoets, C; Debets, R; Drexhage, J; Ronteltap, C; Sebestyén, Z; Willemsen, RA | 1 |
Cohen, CJ; El-Gamil, M; Li, YF; Morgan, RA; Robbins, PF; Rosenberg, SA | 1 |
Bowen, G; Cannon-Albright, LA; Chen, W; Eliason, MJ; Florell, SR; Hansen, CB; Harris, RM; Hart, M; Leachman, SA; Porter-Gill, P; Sturm, RA; Swinyer, L | 1 |
Demopoulos, HB; Duke, PS | 1 |
Fujita, K; Ito, S; Jimbow, K; Kato, T; Kiyota, M | 1 |
Jergil, B; Lindbladh, C; Rorsman, H; Rosengren, E | 1 |
Ito, S; Ito, Y; Jimbow, K; Kasuga, T; Miura, S | 1 |
Ichihashi, M; Mishima, Y; Mojamdar, M | 1 |
Dewey, DL; Gaugas, JM | 1 |
Cooksey, CJ; Land, EJ; Ramsden, CA; Riley, PA | 1 |
Downing, AK; Dwek, RA; Mori, K; Opdenakker, G; Rudd, PM | 1 |
Hoon, DS; Irie, RF; Morton, DL; Saxton, RE; Takeyama, H | 1 |
Benathan, M | 2 |
Bouchard, B; del Marmol, V; Ghanem, G; Ito, S; Libert, A; Solano, F; Wakamatsu, K | 1 |
Arstrand, K; Dizdar, N; Kågedal, B; Kullman, A | 1 |
Carlberg, M; Dricu, A; Griffiths, WJ; Hjertman, M; Larsson, O; Sjövall, J; Wejde, J | 1 |
Colella, TA; Engelhard, VH; Gulden, PH; Hunt, DF; Kittlesen, DJ; Shabanowitz, J; Shabanowitz, JA; Skipper, JC; Slingluff, CL; Thompson, LW | 1 |
Jimbow, K | 1 |
Ceha, HM; Medema, RH; Nasser, I; Slebos, RJ | 1 |
Appella, E; Kang, X; Kawakami, Y; Parkhurst, MR; Robbins, PF; Rosenberg, SA; Sakaguchi, K; Tupesis, JP; Wang, X | 1 |
Benathan, M; Furumura, M; Hearing, VJ; Kobayashi, N; Panizzon, RG; Virador, V | 1 |
Dizdar, N; Kågedal, B; Kullman, A | 1 |
Hansson, C; Sterner, O; Thörneby-Andersson, K | 1 |
Chidambaram, A; Fraser, MC; Goldstein, AM; Struewing, JP; Tucker, MA | 1 |
Cerundolo, V; Chen, JL; Chen, YT; Dunbar, PR; Gileadi, U; Gnjatic, S; Jäger, E; Knuth, A; Nagata, Y; Old, LJ; Panicali, DL; Stockert, E | 1 |
Arndt, R; Hartleb, J | 1 |
Comporti, M; Lorenzini, E; Paolicchi, A; Perego, P; Pompella, A; Supino, R; Zunino, F | 1 |
Blum, JS; Cresswell, P; Haque, MA; Hawes, JW; Jackson, SK; Li, P; Maric, M; Phan, UT; Zarour, HM | 1 |
Agrup, G; Falck, B; Kennedy, BM; Rorsman, H; Rosengren, AM; Rosengren, E | 1 |
Agrup, G; Andersson, T; Falck, B; Persson, K; Rorsman, H; Rosengren, AM; Rosengren, E | 1 |
Hashimoto, K; Kanzaki, T; Ohyama, H; Tane, N | 1 |
Aubert, C; Rorsman, H; Rosengren, E; Rougé, F | 1 |
Césarini, JP; Meunier, M | 1 |
Agrup, G | 1 |
Jimbow, K; Pankovich, JM | 1 |
Brötell, H; Hallberg, A; Karg, E; Rorsman, H; Rosengren, E; Tunek, A | 1 |
Ito, S; Jimbow, K; Somayaji, V; Wiebe, LI | 1 |
Brötell, H; Karg, E; Rorsman, H; Rosengren, E | 1 |
Hirai, Y; Hirato, T; Hong, YM; Kamogashira, T; Kikumoto, Y; Masui, Y; Mizuno, K; Nagamura, K; Nakai, S; Ohmoto, Y | 1 |
Aroca, P; Jara, JR; Lozano, JA; Martinez, JH; Solano, F | 1 |
Bothwell, M; Grob, PM; Koprowski, H; Ross, AH | 1 |
Ito, S; Kasuga, T; Matsubara, O; Seki, S; Suzuki, S; Yamada, I | 2 |
Ito, S; Kasuga, T; Matsubara, O; Nakamura, T; Seki, S | 1 |
Rorsman, H; Rosengren, AM; Rosengren, E | 2 |
Dhru, D; Rorsman, H; Rosengren, AM; Rosengren, E; Vogel, CL | 1 |
Agrup, G; Falck, B; Jacobsson, S; Rorsman, H; Rosengren, AM; Rosengren, E | 1 |
Demopoulos, HB; Duke, PS; Landgraf, W; Mitamura, AE | 1 |
Rorsman, H | 1 |
Barth, RF; Dunn, DR | 1 |
Demopoulos, HB; Duke, PS; Yuen, TG | 1 |
Demopoulos, HB; Hourani, BT | 1 |
Prabhakaran, K | 1 |
1 review(s) available for cysteine and Melanoma
Article | Year |
---|---|
Cysteine and indole derivatives as markers for malignant melanoma.
Topics: Biomarkers, Tumor; Chromatography; Cysteine; Gas Chromatography-Mass Spectrometry; Humans; Indoles; Melanoma; Reference Standards; Skin Neoplasms | 2001 |
77 other study(ies) available for cysteine and Melanoma
Article | Year |
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Increased expression of secreted protein acidic and rich in cysteine and tissue inhibitor of metalloproteinase-3 in epidermotropic melanoma metastasis.
Topics: Antigens, CD; beta Catenin; Cadherins; Cell Line, Tumor; Cysteine; Humans; Melanoma; Osteonectin; Skin Neoplasms; Tissue Inhibitor of Metalloproteinase-3 | 2021 |
LncRNA MSC-AS1, as an oncogene in melanoma, promotes the proliferation and glutaminolysis by regulating the miR-330-3p/ YAP1 axis.
Topics: Alanine; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cysteine; Gene Expression Regulation, Neoplastic; Glutamates; Glutaminase; Glutamine; Humans; Ketoglutaric Acids; Melanoma; MicroRNAs; Oncogenes; RNA, Long Noncoding; Serine; YAP-Signaling Proteins | 2022 |
Shikonin Causes Non-apoptotic Cell Death in B16F10 Melanoma.
Topics: Apoptosis; Cell Line, Tumor; Cysteine; Humans; Melanoma; Naphthoquinones; Necrosis; Reactive Oxygen Species | 2023 |
Hypoxia-Induced Changes in L-Cysteine Metabolism and Antioxidative Processes in Melanoma Cells.
Topics: Antioxidants; Cystathionine beta-Synthase; Cysteine; Humans; Melanoma; Thioredoxin-Disulfide Reductase | 2023 |
Modulating multi-functional ERK complexes by covalent targeting of a recruitment site in vivo.
Topics: Animals; Apoptosis; Binding Sites; Cell Line, Tumor; Cysteine; Dioxanes; HEK293 Cells; Humans; MAP Kinase Signaling System; Melanoma; Mice, Nude; Mitogen-Activated Protein Kinase 1; Molecular Dynamics Simulation; Protein Binding; Protein Kinase Inhibitors; Thiazoles; Xenograft Model Antitumor Assays | 2019 |
Differences in cell death in methionine versus cysteine depletion.
Topics: Activating Transcription Factor 4; Apoptosis; Cell Line, Tumor; Cell Proliferation; Chemotherapy, Adjuvant; Cysteine; Ferroptosis; Gene Expression Regulation, Neoplastic; Homocysteine; Humans; Lipid Peroxidation; Melanoma; Methionine; NF-E2-Related Factor 2; Transcriptome | 2021 |
CD8
Topics: Amino Acid Transport System y+; Animals; B7-H1 Antigen; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Cysteine; Female; Ferroptosis; Fusion Regulatory Protein 1, Heavy Chain; Humans; Immunotherapy; Interferon-gamma; Lipid Peroxidation; Melanoma; Mice; Neoplasms; Nivolumab; Reactive Oxygen Species; Treatment Outcome | 2019 |
Chondroitin sulfate proteoglycan 4 enhanced melanoma motility and growth requires a cysteine in the core protein transmembrane domain.
Topics: Antigens; Chondroitin Sulfate Proteoglycans; Cysteine; Humans; Melanoma; Membrane Proteins; Proteoglycans; Skin Neoplasms; Transfection | 2019 |
Evaluation of N-acetyl-S-(p-chlorophenylcarbamoyl)cysteine as an irreversible inhibitor of mammalian thioredoxin reductase1.
Topics: Cell Line, Tumor; Cysteine; Dialysis; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Mass Spectrometry; Melanoma; NADP; Sulfonylurea Compounds; Thioredoxin Reductase 1; Thioredoxin-Disulfide Reductase | 2016 |
N‑acetyl-S-(p-chlorophenylcarbamoyl)cysteine induces mitochondrial-mediated apoptosis and suppresses migration in melanoma cells.
Topics: Antineoplastic Agents; Apoptosis; Calcium; Caspase 3; Caspase 9; Cell Line, Tumor; Cysteine; Gene Expression Regulation, Neoplastic; Humans; Melanoma; Membrane Potential, Mitochondrial; Mitochondria; Neoplasm Metastasis; Oxidative Stress; Reactive Oxygen Species; Sulfonylurea Compounds | 2015 |
Paclitaxel-induced aberrant mitosis and mitotic slippage efficiently lead to proliferative death irrespective of canonical apoptosis and p53.
Topics: Apoptosis; Cell Cycle Checkpoints; Cell Proliferation; Cell Survival; Clone Cells; Cysteine; DNA; Genes, Reporter; HeLa Cells; Humans; Kinesins; Melanoma; Mitochondrial Membranes; Mitosis; Paclitaxel; Permeability; Phenotype; Reproducibility of Results; Time-Lapse Imaging; Tumor Suppressor Protein p53 | 2016 |
Differential sensitivity of various human tumour-derived cell types to apoptosis by organic derivatives of selenium.
Topics: Adenocarcinoma; Adolescent; Adult; Animals; Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Cysteine; Epithelial Cells; Female; Humans; Liver Neoplasms; Male; Melanoma; Middle Aged; Neoplasms; Neuroectodermal Tumors, Primitive, Peripheral; Organoselenium Compounds; Selenium Compounds; Selenocysteine; Selenomethionine; Skin Neoplasms | 2009 |
CD34(+) fibrocytes in melanocytic nevi and malignant melanomas of the skin.
Topics: Actins; Antigens, CD34; Connective Tissue; Cysteine; Humans; Melanoma; Nevus, Pigmented; Osteonectin; Phenotype; Retrospective Studies; Skin Neoplasms | 2008 |
Peptides with dual binding specificity for HLA-A2 and HLA-E are encoded by alternatively spliced isoforms of the antioxidant enzyme peroxiredoxin 5.
Topics: Alternative Splicing; Amino Acid Motifs; Antigens, Neoplasm; Antioxidants; Catalytic Domain; Cell Line, Tumor; Clone Cells; Cysteine; Histocompatibility Antigens Class I; HLA Antigens; HLA-A2 Antigen; HLA-E Antigens; Humans; Immunity, Cellular; Killer Cells, Natural; Melanoma; Oxidative Stress; Peptides; Peroxiredoxins; Protein Binding; Protein Isoforms; Protein Stability; Sequence Deletion; T-Lymphocytes, Cytotoxic | 2009 |
Use of oral N-acetylcysteine for protection of melanocytic nevi against UV-induced oxidative stress: towards a novel paradigm for melanoma chemoprevention.
Topics: Acetylcysteine; Administration, Oral; Adult; Aged; Anticarcinogenic Agents; Antioxidants; Cysteine; Female; Glutathione; Humans; Male; Melanoma; Middle Aged; Nevus, Pigmented; Oxidative Stress; Risk; Skin Neoplasms; Time Factors; Ultraviolet Rays | 2009 |
The cystine/cysteine cycle and GSH are independent and crucial antioxidant systems in malignant melanoma cells and represent druggable targets.
Topics: Antioxidants; Arsenic Trioxide; Arsenicals; Blotting, Western; Buthionine Sulfoximine; Cell Survival; Cysteine; Cystine; Glutathione; Glycine; HMGB1 Protein; Humans; Immunohistochemistry; Melanoma; Oxidation-Reduction; Oxides; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Tumor Cells, Cultured | 2011 |
Copper-mediated cross-linking of S100A4, but not of S100A2, results in proinflammatory effects in melanoma cells.
Topics: Amino Acid Sequence; Cell Line, Tumor; Chemotactic Factors; Copper; Cross-Linking Reagents; Cysteine; Glycation End Products, Advanced; Humans; Inflammation; Melanoma; Molecular Sequence Data; NF-kappa B; Oxidation-Reduction; Protein Structure, Secondary; Receptor for Advanced Glycation End Products; Receptors, Immunologic; S100 Calcium-Binding Protein A4; S100 Proteins; Tumor Microenvironment; Tumor Necrosis Factor-alpha | 2011 |
Palmitoylated TMX and calnexin target to the mitochondria-associated membrane.
Topics: Amino Acid Sequence; Animals; Calnexin; Cell Line, Tumor; Cysteine; Dogs; Endoplasmic Reticulum; HeLa Cells; Heme Oxygenase-1; Humans; Intracellular Membranes; Lipoylation; Melanoma; Membrane Glycoproteins; Membrane Proteins; Mice; Mitochondria; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Disulfide Reductase (Glutathione); Protein Disulfide-Isomerases; Protein Processing, Post-Translational; Protein Structure, Tertiary; Protein Transport; Thioredoxins | 2012 |
Comprehensive identification of novel post-translational modifications in cellular peroxiredoxin 6.
Topics: Amino Acid Sequence; Animals; Cell Line, Tumor; Chromatography, High Pressure Liquid; Cysteine; Liver; Melanoma; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Models, Molecular; Molecular Sequence Data; Peroxiredoxin VI; Protein Processing, Post-Translational; Proteins; Proteome; Proteomics; Tandem Mass Spectrometry | 2012 |
A novel radiopharmaceutical for detection of malignant melanoma, based on melanin formation: 3-iodo-4-hydroxyphenyl-L-cysteine.
Topics: Animals; Cysteine; Isotope Labeling; Melanins; Melanoma; Mice; Mice, Inbred C57BL; Organ Specificity; Predictive Value of Tests; Radiopharmaceuticals; Skin Neoplasms; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Whole-Body Counting | 2003 |
Cysteine but not glutathione modulates the radiosensitivity of human melanoma cells by affecting both survival and DNA damage.
Topics: Buthionine Sulfoximine; Cell Line, Tumor; Cell Survival; Comet Assay; Cysteine; DNA Damage; Dose-Response Relationship, Radiation; Glutathione; Humans; Melanoma; Pigmentation; Radiation Tolerance; Radiation-Sensitizing Agents | 2004 |
Effect of new antioxidant cysteinyl-flavanol conjugates on skin cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Catechin; Cell Cycle; Cysteine; Electron Transport; Flavonoids; Free Radical Scavengers; Humans; Keratinocytes; Melanoma; Skin Neoplasms; Tumor Cells, Cultured; Vitis | 2005 |
New cysteine derivatives with antiproliferative activity on melanoma cells.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cysteine; Drug Design; Enzyme Inhibitors; Fibroblasts; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Melanoma; Models, Chemical | 2006 |
CD8 alpha coreceptor to improve TCR gene transfer to treat melanoma: down-regulation of tumor-specific production of IL-4, IL-5, and IL-10.
Topics: Amino Acid Motifs; CD8 Antigens; Cell Differentiation; Cell Line; Cell Line, Tumor; Cysteine; Cytotoxicity, Immunologic; Down-Regulation; Epitopes, T-Lymphocyte; Gene Transfer Techniques; gp100 Melanoma Antigen; HLA-A2 Antigen; Humans; Interleukin-10; Interleukin-4; Interleukin-5; Melanoma; Membrane Glycoproteins; Peptide Fragments; Protein Binding; Receptors, Antigen, T-Cell, alpha-beta; Th1 Cells; Transduction, Genetic | 2006 |
Enhanced antitumor activity of T cells engineered to express T-cell receptors with a second disulfide bond.
Topics: Cysteine; Genetic Therapy; Humans; Immunotherapy, Adoptive; Jurkat Cells; Leukocytes, Mononuclear; Melanoma; Protein Engineering; Receptors, Antigen, T-Cell; T-Lymphocytes | 2007 |
Multiple primary melanomas in a CDKN2A mutation carrier exposed to ionizing radiation.
Topics: 5' Untranslated Regions; Adult; Arginine; Cysteine; Environmental Exposure; Female; Genes, p16; Genetic Predisposition to Disease; Hair Color; Heterozygote; Humans; Melanoma; Mutation; Neoplasms, Multiple Primary; Neoplasms, Radiation-Induced; Nuclear Weapons; Receptor, Melanocortin, Type 1; Skin Neoplasms | 2007 |
In vivo necrosis of large S-91 mouse melanomas by DL-B-phenyllactic acid plus L-cysteine.
Topics: Animals; Cysteine; Lactates; Male; Melanoma; Mice; Neoplasms, Experimental | 1967 |
Protein-bound dopa and 5-S-cysteinyldopa in non-melanogenic tissues.
Topics: Animals; Cysteine; Cysteinyldopa; Dihydroxyphenylalanine; Free Radicals; Indoles; Melanins; Melanoma; Mice; Mice, Inbred Strains; Monophenol Monooxygenase; Protein Binding; Rats; Rats, Inbred Strains; Tyrosine | 1983 |
Inactivation of human tyrosinase by cysteine. Protection by dopa and tyrosine.
Topics: Catalase; Catechol Oxidase; Cells, Cultured; Cysteine; Humans; In Vitro Techniques; Levodopa; Melanoma; Monophenol Monooxygenase; Superoxide Dismutase; Tyrosine | 1984 |
[Utilization of melanin precursors for experimental chemotherapy of malignant melanoma].
Topics: Animals; Catecholamines; Cysteamine; Cysteine; Dihydroxyphenylalanine; Melanins; Melanocytes; Melanoma; Mice; Monophenol Monooxygenase; Neoplasms, Experimental; Skin Neoplasms | 1984 |
Effect of DOPA-loading on glutathione-dependent 5-S-cysteinyldopa genesis in melanoma cells in vitro.
Topics: Animals; Cells, Cultured; Cricetinae; Culture Media; Cysteine; Cysteinyldopa; Dihydroxyphenylalanine; Drug Synergism; Fibroblasts; Glutathione; Humans; In Vitro Techniques; Melanoma; Mice; Neoplasms, Experimental; Skin Neoplasms; Stimulation, Chemical; Tyrosine | 1982 |
Inhibition of proliferation of cultured cells by polyamine and cysteine interaction.
Topics: Animals; Cell Division; Cells, Cultured; Cysteine; Drug Interactions; Melanoma; Mice; Spermidine | 1980 |
Tyrosinase-mediated cytotoxicity of 4-substituted phenols: quantitative structure-thiol-reactivity relationships of the derived o-quinones.
Topics: Antineoplastic Agents; Cell Survival; Cysteine; Glutathione; Kinetics; Melanoma; Monophenol Monooxygenase; Phenols; Quinones; Spectrum Analysis; Structure-Activity Relationship | 1995 |
The activation of type 1 and type 2 plasminogen by type I and type II tissue plasminogen activator.
Topics: Amino Acid Sequence; Chromatography, Affinity; Cysteine; Disulfides; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Fibrinogen; Glycosylation; Humans; Isoenzymes; Kinetics; Macromolecular Substances; Melanoma; Models, Molecular; Molecular Weight; Peptide Fragments; Plasminogen; Plasminogen Activator Inhibitor 1; Protein Structure, Secondary; Tissue Plasminogen Activator; Tumor Cells, Cultured | 1995 |
Growth inhibition and modulation of cell markers of melanoma by S-allyl cysteine.
Topics: Animals; Cell Division; Cysteine; Dose-Response Relationship, Drug; Gangliosides; Humans; Melanins; Melanoma; Mice; Thymidine; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1993 |
Modulation of 5-S-cysteinyldopa formation by tyrosinase activity and intracellular thiols in human melanoma cells.
Topics: Buthionine Sulfoximine; Catechols; Cell Line; Cysteine; Cysteinyldopa; Glutathione; Humans; Melanoma; Microscopy, Electron; Monophenol Monooxygenase; Tumor Cells, Cultured | 1996 |
Cysteine deprivation promotes eumelanogenesis in human melanoma cells.
Topics: Cysteine; Glutathione; Humans; Melanins; Melanoma; Membrane Glycoproteins; Oxidoreductases; Proteins; Tumor Cells, Cultured | 1996 |
Opposite regulation of tyrosinase and glutathione peroxidase by intracellular thiols in human melanoma cells.
Topics: Buthionine Sulfoximine; Carmustine; Cysteine; Cystine; Glutathione; Glutathione Peroxidase; Humans; Melanins; Melanoma; Monophenol Monooxygenase; Oxidative Stress; Sodium Selenite; Sulfhydryl Compounds; Tumor Cells, Cultured | 1997 |
Effects on interstitial glutathione, cysteine and 5-S-cysteinyldopa of buthionine sulphoximine in human melanoma transplants.
Topics: Acetylcysteine; Animals; Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Cysteine; Cysteinyldopa; Drug Interactions; Enzyme Inhibitors; Glutathione; Humans; Melanoma; Mice; Mice, Inbred BALB C; Mice, Nude; Microdialysis; Neoplasm Transplantation; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1997 |
Evidence for protein dolichylation.
Topics: Autoradiography; Chromatography, High Pressure Liquid; Colonic Neoplasms; Cysteine; Dolichols; Hepatoblastoma; Humans; Liver Neoplasms; Melanoma; Mevalonic Acid; Neoplasm Proteins; Peptide Fragments; Protein Prenylation; Sulfur Radioisotopes; Tritium; Tumor Cells, Cultured | 1997 |
Human melanoma patients recognize an HLA-A1-restricted CTL epitope from tyrosinase containing two cysteine residues: implications for tumor vaccine development.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Cancer Vaccines; Cysteine; Cytotoxicity, Immunologic; HLA-A1 Antigen; Humans; Immunodominant Epitopes; Melanoma; Monophenol Monooxygenase; Peptide Fragments; Serine; T-Lymphocytes, Cytotoxic; Tumor Cells, Cultured | 1998 |
[Development of targeted chemoradiotherapy for malignant melanoma by exploitation of metabolic pathway].
Topics: Animals; Antineoplastic Agents; Cysteamine; Cysteine; DNA Damage; Humans; Melanins; Melanoma; Mice; Monophenol Monooxygenase; Oxidative Stress; Phenols; Skin Neoplasms; Substrate Specificity; Tumor Cells, Cultured; Tyrosine | 1998 |
Several noncontiguous domains of CDK4 are involved in binding to the P16 tumor suppressor protein.
Topics: Arginine; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinases; Cysteine; Glutathione Transferase; Humans; Melanoma; Mutagenesis, Site-Directed; Mutation; Proto-Oncogene Proteins; Recombinant Fusion Proteins; Structure-Activity Relationship; Tyrosine | 1998 |
Identification of new melanoma epitopes on melanosomal proteins recognized by tumor infiltrating T lymphocytes restricted by HLA-A1, -A2, and -A3 alleles.
Topics: Adult; Alleles; Amino Acid Sequence; Amino Acid Substitution; Antigens, Neoplasm; Cysteine; DNA, Complementary; DNA, Neoplasm; Epitopes; Female; gp100 Melanoma Antigen; HLA-A1 Antigen; HLA-A2 Antigen; HLA-A3 Antigen; Humans; Lymphocytes, Tumor-Infiltrating; Male; Melanoma; Membrane Glycoproteins; Molecular Sequence Data; Monophenol Monooxygenase; Neoplasm Proteins; Oxidation-Reduction; Peptide Fragments; Sequence Alignment; Sequence Homology, Amino Acid; T-Lymphocytes, Cytotoxic; Tumor Cells, Cultured | 1998 |
Co-regulation of melanin precursors and tyrosinase in human pigment cells: roles of cysteine and glutathione.
Topics: Buthionine Sulfoximine; Cells, Cultured; Cysteine; Cysteinyldopa; Dihydroxyphenylalanine; Glutathione; Humans; Infant, Newborn; Male; Melanins; Melanocytes; Melanoma; Melanosomes; Monophenol Monooxygenase; Neoplasm Proteins; Skin Neoplasms; Tumor Cells, Cultured; Tyrosine | 1999 |
Comparison of N-acetylcysteine and l-2-oxothiazolidine-4-carboxylate as cysteine deliverers and glutathione precursors in human malignant melanoma transplants in mice.
Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Cysteine; Cysteinyldopa; Enzyme Inhibitors; Glutathione; Humans; Melanoma; Melanoma, Experimental; Mice; Mice, Nude; Microdialysis; Neoplasm Transplantation; Protein Precursors; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Transplantation, Heterologous; Tumor Cells, Cultured | 2000 |
Tyrosinase-mediated formation of a reactive quinone from the depigmenting agents, 4-tert-butylphenol and 4-tert-butylcatechol.
Topics: Agaricales; Antioxidants; Catechols; Chromatography, High Pressure Liquid; Cysteine; Glutathione; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Magnetic Resonance Spectroscopy; Melanocytes; Melanoma; Monophenol Monooxygenase; Oxidation-Reduction; Phenols; Pigmentation; Pigments, Biological; Quinones; Tumor Cells, Cultured | 2000 |
Genotype-phenotype relationships in U.S. melanoma-prone families with CDKN2A and CDK4 mutations.
Topics: Adolescent; Adult; Age Factors; Aged; Arginine; Aspartic Acid; Cyclin-Dependent Kinases; Cysteine; Genes, p16; Genotype; Germ-Line Mutation; Glycine; Haplotypes; Humans; Melanoma; Middle Aged; Nevus; Pancreatic Neoplasms; Phenotype; Skin Neoplasms; Statistics, Nonparametric; Tryptophan; United States; Valine | 2000 |
Identification of NY-ESO-1 peptide analogues capable of improved stimulation of tumor-reactive CTL.
Topics: Amino Acid Substitution; Antigen Presentation; Antigens, Neoplasm; Cysteine; Cytotoxicity, Immunologic; Epitopes, T-Lymphocyte; HLA-A2 Antigen; Humans; Intracellular Fluid; Lymphocyte Activation; Melanoma; Membrane Proteins; Peptide Fragments; Protein Binding; Proteins; T-Lymphocytes, Cytotoxic; Tumor Cells, Cultured | 2000 |
Extra-cellular thiol metabolism in clones of human metastatic melanoma with different gamma-glutamyl transpeptidase expression: implications for cell response to platinum-based drugs.
Topics: Antineoplastic Agents; Chromatography, High Pressure Liquid; Cysteine; Disulfides; gamma-Glutamyltransferase; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Humans; Hydrogen Peroxide; Melanoma; Organoplatinum Compounds; Oxidants; Skin Neoplasms; Tumor Cells, Cultured | 2002 |
Absence of gamma-interferon-inducible lysosomal thiol reductase in melanomas disrupts T cell recognition of select immunodominant epitopes.
Topics: Antigen-Presenting Cells; CD4-Positive T-Lymphocytes; Cell Division; Cysteine; Epitopes, T-Lymphocyte; Humans; Immunodominant Epitopes; Interferon-gamma; Mass Spectrometry; Melanoma; Oxidation-Reduction; Oxidoreductases; Oxidoreductases Acting on Sulfur Group Donors; Peptide Fragments; T-Lymphocytes; Transfection; Tumor Cells, Cultured | 2002 |
Formation of cysteinyldopa from glutathionedopa in melanoma.
Topics: Animals; Cysteine; Depression, Chemical; Dihydroxyphenylalanine; Glutathione; Guinea Pigs; Humans; Kidney; Lung; Lung Neoplasms; Melanoma; Mice; Neoplasm Metastasis; Skin Neoplasms; Stimulation, Chemical | 1975 |
5-S-cysteinyldopa in the plasma of melanoma patients and the renal clearance of this amino acid.
Topics: Adult; Breast Neoplasms; Cysteine; Dihydroxyphenylalanine; Humans; Liver Neoplasms; Lung Neoplasms; Male; Melanoma; Neoplasm Metastasis; Skin Neoplasms | 1975 |
Collagenolytic activities of cultured human malignant melanoma cells.
Topics: Adult; Cells, Cultured; Cysteine; Edetic Acid; Humans; Male; Melanoma; Microbial Collagenase; Middle Aged; Tropocollagen | 1978 |
Differentiation of melanocytes in cultures of primary malignant melanoma indicated by 5-S-cysteinyldopa formation.
Topics: Cell Differentiation; Cells, Cultured; Cysteine; Dihydroxyphenylalanine; Humans; Melanocytes; Melanoma | 1975 |
[Urinary 5-S-cysteinyldopa levels in patients with malignant melanoma. Preliminary results].
Topics: Creatinine; Cysteine; Dihydroxyphenylalanine; Melanoma; Neoplasm Metastasis; Skin Neoplasms | 1975 |
[Chemical diagnosis of melanoma].
Topics: Cysteine; Dihydroxyphenylalanine; Humans; Melanoma; Neoplasm Metastasis; Skin Neoplasms | 1976 |
Tyrosine transport in a human melanoma cell line as a basis for selective transport of cytotoxic analogues.
Topics: Amino Acids; Amino Acids, Cyclic; Biological Transport, Active; Cysteine; Drug Delivery Systems; Evaluation Studies as Topic; Humans; Kinetics; Melanoma; Sodium; Tumor Cells, Cultured; Tyrosine | 1991 |
Glutathione in human melanoma cells. Effects of cysteine, cysteine esters and glutathione isopropyl ester.
Topics: Acetylcysteine; Cysteine; Expectorants; Glutathione; Humans; Melanoma; Skin Neoplasms; Tumor Cells, Cultured | 1990 |
The synthesis of 4-S-cysteinyl-[U-14C]phenol, an experimental antimelanoma agent.
Topics: Antineoplastic Agents; Cysteine; Melanoma | 1989 |
Modulation of glutathione level in cultured human melanoma cells.
Topics: Antimetabolites; Buthionine Sulfoximine; Cell Line; Cell Survival; Cysteine; Glutathione; Humans; Melanoma; Methionine Sulfoximine; Tumor Cells, Cultured; Vitamin K | 1989 |
Site-specific mutagenesis of the human interleukin-1 beta gene: structure-function analysis of the cysteine residues.
Topics: Codon; Cysteine; DNA Restriction Enzymes; DNA, Recombinant; DNA, Single-Stranded; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Humans; Interleukin-1; Melanoma; Molecular Weight; Mutation; Plasmids; Structure-Activity Relationship; Tumor Cells, Cultured | 1988 |
The role of sulfhydryl compounds in mammalian melanogenesis: the effect of cysteine and glutathione upon tyrosinase and the intermediates of the pathway.
Topics: Animals; Catechol Oxidase; Cysteine; Glutathione; Melanins; Melanoma; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Monophenol Monooxygenase; Tyrosine 3-Monooxygenase | 1988 |
Characterization of the human melanoma nerve growth factor receptor.
Topics: Antibodies, Monoclonal; Cell Line; Cysteine; Electrophoresis, Polyacrylamide Gel; Glucosamine; Humans; Melanoma; Mercaptoethanol; Molecular Weight; Phosphorylation; Protein Processing, Post-Translational; Receptors, Cell Surface; Receptors, Nerve Growth Factor | 1985 |
The killing effects of 4-S-cysteinylcatechol and analogues on human melanoma cells.
Topics: Antineoplastic Agents; Cell Survival; Chemical Phenomena; Chemistry; Cysteine; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Female; Humans; Melanoma; Tumor Cells, Cultured | 1988 |
Specific incorporation of 4-S-cysteinylphenol into human melanoma cells.
Topics: Autoradiography; Cysteine; Humans; Melanoma; Microscopy, Electron; Time Factors; Tumor Cells, Cultured | 1988 |
The cytotoxicity of cysteinylcatechols and related compounds to human melanoma cells in vitro.
Topics: Antineoplastic Agents; Catechols; Cell Division; Cell Line; Cell Survival; Cysteine; Dose-Response Relationship, Drug; Humans; Levodopa; Melanoma; Phenols; Time Factors | 1987 |
Fluorometry of a DOPA peptide and its thioether.
Topics: Carbon Isotopes; Catechol Oxidase; Catechols; Chromatography, Paper; Cysteine; Dihydroxyphenylalanine; Dipeptides; Ethers; Fluorescence; Fluorometry; Melanoma; Peptides; Phenylalanine; Pigments, Biological; Spectrophotometry; Sulfhydryl Reagents; Sulfur; Tyrosine | 1971 |
Dopa and 5-S-cysteinyldopa in malignant melanoma in Ugandan Africans.
Topics: Adult; Aged; Black People; Cysteine; Dihydroxyphenylalanine; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Skin Neoplasms; Spectrophotometry; Uganda | 1974 |
5-S-cysteinyldopa in melanomas of Caucasians.
Topics: Adult; Aged; Chromatography; Cysteine; Dihydroxyphenylalanine; Female; Fluorometry; Hair; Humans; Melanoma; Middle Aged; Neoplasm Metastasis; Pigmentation; Skin Neoplasms; White People | 1974 |
Study of S91 mouse melanomas by electron paramagnetic resonance spectroscopy and tissue culture. I. The effect of cysteine on blue light signals and on growth in vitro.
Topics: Animals; Culture Techniques; Cysteine; Electron Spin Resonance Spectroscopy; Humans; Melanoma; Mice; Neoplasms, Experimental | 1966 |
The melanocyte illuminated.
Topics: Animals; Cysteine; Dihydroxyphenylalanine; Histocytochemistry; Humans; Melanocytes; Melanoma | 1974 |
Determination of 5-S-cysteinyldopa in melanomas with a fluorimetric method.
Topics: Animals; Black People; Cysteine; Dihydroxyphenylalanine; Dopamine; Fluorometry; Guinea Pigs; Hair; Humans; Melanoma; Mice; Neoplasm Metastasis; Pigmentation; Skin; White People | 1973 |
Identification of melanoma cells by formaldehyde-induced fluorescence.
Topics: Adenocarcinoma; Cell Line; Culture Techniques; Cysteine; Dopamine; Fluorescence; Formaldehyde; HeLa Cells; Humans; Melanoma; Tyrosine; Ultraviolet Rays | 1974 |
In vitro growth inhibition of S-91 mouse melanomas by tyrosinase substrate analogs with and without L-cysteine.
Topics: Animals; Catechol Oxidase; Chemical Phenomena; Chemistry; Cysteine; In Vitro Techniques; Melanoma; Mice; Neoplasms, Experimental; Phenylalanine; Tyrosine | 1967 |
Inhibition of S-91 mouse melanoma metastases and growth by D-penicillamine.
Topics: Animals; Catechol Oxidase; Copper; Cysteine; Melanoma; Mice; Neoplasm Metastasis; Penicillamine; Tyrosine | 1969 |
Unusual effects of reducing agents on 0-diphenoloxidase of Mycobacterium leprae.
Topics: Animals; Ascorbic Acid; Azides; Basidiomycota; Catechol Oxidase; Cell-Free System; Cyanides; Cysteine; Cystine; Dihydroxyphenylalanine; Glutathione; Humans; Manometry; Melanins; Melanoma; Mice; Mycobacterium leprae; Oxidation-Reduction; Quinones; Skin; Species Specificity; Spectrophotometry; Spleen; Stereoisomerism; Tissue Extracts; Tyrosine | 1971 |