cysteine and Melanoma

cysteine has been researched along with Melanoma in 78 studies

Research

Studies (78)

TimeframeStudies, this research(%)All Research%
pre-199030 (38.46)18.7374
1990's15 (19.23)18.2507
2000's18 (23.08)29.6817
2010's10 (12.82)24.3611
2020's5 (6.41)2.80

Authors

AuthorsStudies
Kiniwa, Y; Meling, MT; Ogawa, E; Okuyama, R; Sato, Y1
Ji, G; Luo, B; Shen, G; Tian, T1
Ahmad, H; Baer, RW; Cox, JL; Crotts, MS; Jacobs, JC1
Janik, K; Jurkowska, H; Rydz, L; Wróbel, M1
Anslyn, EV; Cano, M; Dalby, KN; Ebelt, ND; Edupuganti, R; Ghose, R; Harger, M; Johnson, WH; Kaoud, TS; Park, J; Piserchio, A; Pridgen, JR; Radwan, MF; Ren, P; Sammons, R; Tavares, CDJ; Tsai, KY; Van Ravenstein, SX; Warthaka, M; Zamora-Olivares, D1
Bird, JT; Byrum, SD; Miousse, IR; Morehead, LC; Wallis, KF1
Chan, TA; Chinnaiyan, A; Choi, JE; Cieslik, M; Georgiou, G; Gijón, M; Green, M; Gu, W; Johnson, JK; Kennedy, PD; Kryczek, I; Lamb, C; Lang, X; Lawrence, TS; Li, G; Li, J; Li, W; Liao, P; Liu, R; Sell, A; Stone, E; Szeliga, W; Tanno, Y; Vatan, L; Wang, W; Wei, S; Xia, H; Zhang, H; Zhou, J; Zou, W1
Conner, S; He, J; Li, G; McCarthy, JB; Price, MA; Sachs, J; Turley, EA; Wanshura, LEC; Welch, DR; Yang, J; Yi, M1
Chen, W; Chen, Z; Guan, X; Jiang, Z; Lin, N; Zhang, X; Zheng, Z1
Chen, W; Feng, J; Jiang, Z; Ling, Y; Zhang, X1
Maesawa, C; Nishiya, M; Shibazaki, M; Yasuhira, S1
Gangapurkar, B; Jariwalla, RJ; Nakamura, D1
Barth, PJ; Moll, I; Nowak, K; Wessel, C; Westhoff, CC1
Anichini, A; Bersani, I; Millo, E; Mingari, MC; Molla, A; Moretta, L; Nicolini, G; Pietra, G; Sensi, M; Vegetti, C; Weiss, E1
Boucher, KM; Cassidy, P; Cotter, MA; Florell, SR; Goodson, AG; Grossman, D; Liu, T; Wade, M1
Castellani, P; Ciriolo, MR; Delfino, L; Lucibello, M; Rubartelli, A; Venè, R1
Haase-Kohn, C; Lenk, J; Pietzsch, J; Wolf, S1
Benson, MD; Berthiaume, LG; Bui, M; Ellgaard, L; Lynes, EM; Schneider, B; Simmen, T; Yap, MC1
Jeong, J; Kim, Y; Kyung Seong, J; Lee, KJ1
Arano, Y; Garcia Flores, L; Jinnouchi, S; Kataoka, H; Kawai, K; Nagamachi, S; Nishii, R; Tamura, S1
Dubois, J; Duez, P; Ghanem, G; Kinnaert, E; Morandini, R; Van Houtte, P1
Cascante, M; Centelles, JJ; Jimenez, A; Julià, L; Lozano, C; Torres, JL1
Boyle, GM; Fairlie, DP; Lucke, AJ; Parsons, PG1
Berrevoets, C; Debets, R; Drexhage, J; Ronteltap, C; Sebestyén, Z; Willemsen, RA1
Cohen, CJ; El-Gamil, M; Li, YF; Morgan, RA; Robbins, PF; Rosenberg, SA1
Bowen, G; Cannon-Albright, LA; Chen, W; Eliason, MJ; Florell, SR; Hansen, CB; Harris, RM; Hart, M; Leachman, SA; Porter-Gill, P; Sturm, RA; Swinyer, L1
Demopoulos, HB; Duke, PS1
Fujita, K; Ito, S; Jimbow, K; Kato, T; Kiyota, M1
Jergil, B; Lindbladh, C; Rorsman, H; Rosengren, E1
Ito, S; Ito, Y; Jimbow, K; Kasuga, T; Miura, S1
Ichihashi, M; Mishima, Y; Mojamdar, M1
Dewey, DL; Gaugas, JM1
Cooksey, CJ; Land, EJ; Ramsden, CA; Riley, PA1
Downing, AK; Dwek, RA; Mori, K; Opdenakker, G; Rudd, PM1
Hoon, DS; Irie, RF; Morton, DL; Saxton, RE; Takeyama, H1
Benathan, M2
Bouchard, B; del Marmol, V; Ghanem, G; Ito, S; Libert, A; Solano, F; Wakamatsu, K1
Arstrand, K; Dizdar, N; Kågedal, B; Kullman, A1
Carlberg, M; Dricu, A; Griffiths, WJ; Hjertman, M; Larsson, O; Sjövall, J; Wejde, J1
Colella, TA; Engelhard, VH; Gulden, PH; Hunt, DF; Kittlesen, DJ; Shabanowitz, J; Shabanowitz, JA; Skipper, JC; Slingluff, CL; Thompson, LW1
Jimbow, K1
Ceha, HM; Medema, RH; Nasser, I; Slebos, RJ1
Appella, E; Kang, X; Kawakami, Y; Parkhurst, MR; Robbins, PF; Rosenberg, SA; Sakaguchi, K; Tupesis, JP; Wang, X1
Benathan, M; Furumura, M; Hearing, VJ; Kobayashi, N; Panizzon, RG; Virador, V1
Dizdar, N; Kågedal, B; Kullman, A1
Hansson, C; Sterner, O; Thörneby-Andersson, K1
Chidambaram, A; Fraser, MC; Goldstein, AM; Struewing, JP; Tucker, MA1
Cerundolo, V; Chen, JL; Chen, YT; Dunbar, PR; Gileadi, U; Gnjatic, S; Jäger, E; Knuth, A; Nagata, Y; Old, LJ; Panicali, DL; Stockert, E1
Arndt, R; Hartleb, J1
Comporti, M; Lorenzini, E; Paolicchi, A; Perego, P; Pompella, A; Supino, R; Zunino, F1
Blum, JS; Cresswell, P; Haque, MA; Hawes, JW; Jackson, SK; Li, P; Maric, M; Phan, UT; Zarour, HM1
Agrup, G; Falck, B; Kennedy, BM; Rorsman, H; Rosengren, AM; Rosengren, E1
Agrup, G; Andersson, T; Falck, B; Persson, K; Rorsman, H; Rosengren, AM; Rosengren, E1
Hashimoto, K; Kanzaki, T; Ohyama, H; Tane, N1
Aubert, C; Rorsman, H; Rosengren, E; Rougé, F1
Césarini, JP; Meunier, M1
Agrup, G1
Jimbow, K; Pankovich, JM1
Brötell, H; Hallberg, A; Karg, E; Rorsman, H; Rosengren, E; Tunek, A1
Ito, S; Jimbow, K; Somayaji, V; Wiebe, LI1
Brötell, H; Karg, E; Rorsman, H; Rosengren, E1
Hirai, Y; Hirato, T; Hong, YM; Kamogashira, T; Kikumoto, Y; Masui, Y; Mizuno, K; Nagamura, K; Nakai, S; Ohmoto, Y1
Aroca, P; Jara, JR; Lozano, JA; Martinez, JH; Solano, F1
Bothwell, M; Grob, PM; Koprowski, H; Ross, AH1
Ito, S; Kasuga, T; Matsubara, O; Seki, S; Suzuki, S; Yamada, I2
Ito, S; Kasuga, T; Matsubara, O; Nakamura, T; Seki, S1
Rorsman, H; Rosengren, AM; Rosengren, E2
Dhru, D; Rorsman, H; Rosengren, AM; Rosengren, E; Vogel, CL1
Agrup, G; Falck, B; Jacobsson, S; Rorsman, H; Rosengren, AM; Rosengren, E1
Demopoulos, HB; Duke, PS; Landgraf, W; Mitamura, AE1
Rorsman, H1
Barth, RF; Dunn, DR1
Demopoulos, HB; Duke, PS; Yuen, TG1
Demopoulos, HB; Hourani, BT1
Prabhakaran, K1

Reviews

1 review(s) available for cysteine and Melanoma

ArticleYear
Cysteine and indole derivatives as markers for malignant melanoma.
    Journal of chromatography. B, Biomedical sciences and applications, 2001, Nov-25, Volume: 764, Issue:1-2

    Topics: Biomarkers, Tumor; Chromatography; Cysteine; Gas Chromatography-Mass Spectrometry; Humans; Indoles; Melanoma; Reference Standards; Skin Neoplasms

2001

Other Studies

77 other study(ies) available for cysteine and Melanoma

ArticleYear
Increased expression of secreted protein acidic and rich in cysteine and tissue inhibitor of metalloproteinase-3 in epidermotropic melanoma metastasis.
    The Journal of dermatology, 2021, Volume: 48, Issue:11

    Topics: Antigens, CD; beta Catenin; Cadherins; Cell Line, Tumor; Cysteine; Humans; Melanoma; Osteonectin; Skin Neoplasms; Tissue Inhibitor of Metalloproteinase-3

2021
LncRNA MSC-AS1, as an oncogene in melanoma, promotes the proliferation and glutaminolysis by regulating the miR-330-3p/ YAP1 axis.
    Anti-cancer drugs, 2022, 11-01, Volume: 33, Issue:10

    Topics: Alanine; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cysteine; Gene Expression Regulation, Neoplastic; Glutamates; Glutaminase; Glutamine; Humans; Ketoglutaric Acids; Melanoma; MicroRNAs; Oncogenes; RNA, Long Noncoding; Serine; YAP-Signaling Proteins

2022
Shikonin Causes Non-apoptotic Cell Death in B16F10 Melanoma.
    Anti-cancer agents in medicinal chemistry, 2023, Volume: 23, Issue:16

    Topics: Apoptosis; Cell Line, Tumor; Cysteine; Humans; Melanoma; Naphthoquinones; Necrosis; Reactive Oxygen Species

2023
Hypoxia-Induced Changes in L-Cysteine Metabolism and Antioxidative Processes in Melanoma Cells.
    Biomolecules, 2023, 10-07, Volume: 13, Issue:10

    Topics: Antioxidants; Cystathionine beta-Synthase; Cysteine; Humans; Melanoma; Thioredoxin-Disulfide Reductase

2023
Modulating multi-functional ERK complexes by covalent targeting of a recruitment site in vivo.
    Nature communications, 2019, 11-19, Volume: 10, Issue:1

    Topics: Animals; Apoptosis; Binding Sites; Cell Line, Tumor; Cysteine; Dioxanes; HEK293 Cells; Humans; MAP Kinase Signaling System; Melanoma; Mice, Nude; Mitogen-Activated Protein Kinase 1; Molecular Dynamics Simulation; Protein Binding; Protein Kinase Inhibitors; Thiazoles; Xenograft Model Antitumor Assays

2019
Differences in cell death in methionine versus cysteine depletion.
    Environmental and molecular mutagenesis, 2021, Volume: 62, Issue:3

    Topics: Activating Transcription Factor 4; Apoptosis; Cell Line, Tumor; Cell Proliferation; Chemotherapy, Adjuvant; Cysteine; Ferroptosis; Gene Expression Regulation, Neoplastic; Homocysteine; Humans; Lipid Peroxidation; Melanoma; Methionine; NF-E2-Related Factor 2; Transcriptome

2021
CD8
    Nature, 2019, Volume: 569, Issue:7755

    Topics: Amino Acid Transport System y+; Animals; B7-H1 Antigen; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Cysteine; Female; Ferroptosis; Fusion Regulatory Protein 1, Heavy Chain; Humans; Immunotherapy; Interferon-gamma; Lipid Peroxidation; Melanoma; Mice; Neoplasms; Nivolumab; Reactive Oxygen Species; Treatment Outcome

2019
Chondroitin sulfate proteoglycan 4 enhanced melanoma motility and growth requires a cysteine in the core protein transmembrane domain.
    Melanoma research, 2019, Volume: 29, Issue:4

    Topics: Antigens; Chondroitin Sulfate Proteoglycans; Cysteine; Humans; Melanoma; Membrane Proteins; Proteoglycans; Skin Neoplasms; Transfection

2019
Evaluation of N-acetyl-S-(p-chlorophenylcarbamoyl)cysteine as an irreversible inhibitor of mammalian thioredoxin reductase1.
    Journal of enzyme inhibition and medicinal chemistry, 2016, Volume: 31, Issue:2

    Topics: Cell Line, Tumor; Cysteine; Dialysis; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Mass Spectrometry; Melanoma; NADP; Sulfonylurea Compounds; Thioredoxin Reductase 1; Thioredoxin-Disulfide Reductase

2016
N‑acetyl-S-(p-chlorophenylcarbamoyl)cysteine induces mitochondrial-mediated apoptosis and suppresses migration in melanoma cells.
    Oncology reports, 2015, Volume: 34, Issue:5

    Topics: Antineoplastic Agents; Apoptosis; Calcium; Caspase 3; Caspase 9; Cell Line, Tumor; Cysteine; Gene Expression Regulation, Neoplastic; Humans; Melanoma; Membrane Potential, Mitochondrial; Mitochondria; Neoplasm Metastasis; Oxidative Stress; Reactive Oxygen Species; Sulfonylurea Compounds

2015
Paclitaxel-induced aberrant mitosis and mitotic slippage efficiently lead to proliferative death irrespective of canonical apoptosis and p53.
    Cell cycle (Georgetown, Tex.), 2016, Volume: 15, Issue:23

    Topics: Apoptosis; Cell Cycle Checkpoints; Cell Proliferation; Cell Survival; Clone Cells; Cysteine; DNA; Genes, Reporter; HeLa Cells; Humans; Kinesins; Melanoma; Mitochondrial Membranes; Mitosis; Paclitaxel; Permeability; Phenotype; Reproducibility of Results; Time-Lapse Imaging; Tumor Suppressor Protein p53

2016
Differential sensitivity of various human tumour-derived cell types to apoptosis by organic derivatives of selenium.
    The British journal of nutrition, 2009, Volume: 101, Issue:2

    Topics: Adenocarcinoma; Adolescent; Adult; Animals; Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Cysteine; Epithelial Cells; Female; Humans; Liver Neoplasms; Male; Melanoma; Middle Aged; Neoplasms; Neuroectodermal Tumors, Primitive, Peripheral; Organoselenium Compounds; Selenium Compounds; Selenocysteine; Selenomethionine; Skin Neoplasms

2009
CD34(+) fibrocytes in melanocytic nevi and malignant melanomas of the skin.
    Virchows Archiv : an international journal of pathology, 2008, Volume: 453, Issue:5

    Topics: Actins; Antigens, CD34; Connective Tissue; Cysteine; Humans; Melanoma; Nevus, Pigmented; Osteonectin; Phenotype; Retrospective Studies; Skin Neoplasms

2008
Peptides with dual binding specificity for HLA-A2 and HLA-E are encoded by alternatively spliced isoforms of the antioxidant enzyme peroxiredoxin 5.
    International immunology, 2009, Volume: 21, Issue:3

    Topics: Alternative Splicing; Amino Acid Motifs; Antigens, Neoplasm; Antioxidants; Catalytic Domain; Cell Line, Tumor; Clone Cells; Cysteine; Histocompatibility Antigens Class I; HLA Antigens; HLA-A2 Antigen; HLA-E Antigens; Humans; Immunity, Cellular; Killer Cells, Natural; Melanoma; Oxidative Stress; Peptides; Peroxiredoxins; Protein Binding; Protein Isoforms; Protein Stability; Sequence Deletion; T-Lymphocytes, Cytotoxic

2009
Use of oral N-acetylcysteine for protection of melanocytic nevi against UV-induced oxidative stress: towards a novel paradigm for melanoma chemoprevention.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Dec-01, Volume: 15, Issue:23

    Topics: Acetylcysteine; Administration, Oral; Adult; Aged; Anticarcinogenic Agents; Antioxidants; Cysteine; Female; Glutathione; Humans; Male; Melanoma; Middle Aged; Nevus, Pigmented; Oxidative Stress; Risk; Skin Neoplasms; Time Factors; Ultraviolet Rays

2009
The cystine/cysteine cycle and GSH are independent and crucial antioxidant systems in malignant melanoma cells and represent druggable targets.
    Antioxidants & redox signaling, 2011, Nov-01, Volume: 15, Issue:9

    Topics: Antioxidants; Arsenic Trioxide; Arsenicals; Blotting, Western; Buthionine Sulfoximine; Cell Survival; Cysteine; Cystine; Glutathione; Glycine; HMGB1 Protein; Humans; Immunohistochemistry; Melanoma; Oxidation-Reduction; Oxides; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Tumor Cells, Cultured

2011
Copper-mediated cross-linking of S100A4, but not of S100A2, results in proinflammatory effects in melanoma cells.
    Biochemical and biophysical research communications, 2011, Sep-30, Volume: 413, Issue:3

    Topics: Amino Acid Sequence; Cell Line, Tumor; Chemotactic Factors; Copper; Cross-Linking Reagents; Cysteine; Glycation End Products, Advanced; Humans; Inflammation; Melanoma; Molecular Sequence Data; NF-kappa B; Oxidation-Reduction; Protein Structure, Secondary; Receptor for Advanced Glycation End Products; Receptors, Immunologic; S100 Calcium-Binding Protein A4; S100 Proteins; Tumor Microenvironment; Tumor Necrosis Factor-alpha

2011
Palmitoylated TMX and calnexin target to the mitochondria-associated membrane.
    The EMBO journal, 2012, Jan-18, Volume: 31, Issue:2

    Topics: Amino Acid Sequence; Animals; Calnexin; Cell Line, Tumor; Cysteine; Dogs; Endoplasmic Reticulum; HeLa Cells; Heme Oxygenase-1; Humans; Intracellular Membranes; Lipoylation; Melanoma; Membrane Glycoproteins; Membrane Proteins; Mice; Mitochondria; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Disulfide Reductase (Glutathione); Protein Disulfide-Isomerases; Protein Processing, Post-Translational; Protein Structure, Tertiary; Protein Transport; Thioredoxins

2012
Comprehensive identification of novel post-translational modifications in cellular peroxiredoxin 6.
    Proteomics, 2012, Volume: 12, Issue:9

    Topics: Amino Acid Sequence; Animals; Cell Line, Tumor; Chromatography, High Pressure Liquid; Cysteine; Liver; Melanoma; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Models, Molecular; Molecular Sequence Data; Peroxiredoxin VI; Protein Processing, Post-Translational; Proteins; Proteome; Proteomics; Tandem Mass Spectrometry

2012
A novel radiopharmaceutical for detection of malignant melanoma, based on melanin formation: 3-iodo-4-hydroxyphenyl-L-cysteine.
    Nuclear medicine communications, 2003, Volume: 24, Issue:5

    Topics: Animals; Cysteine; Isotope Labeling; Melanins; Melanoma; Mice; Mice, Inbred C57BL; Organ Specificity; Predictive Value of Tests; Radiopharmaceuticals; Skin Neoplasms; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Whole-Body Counting

2003
Cysteine but not glutathione modulates the radiosensitivity of human melanoma cells by affecting both survival and DNA damage.
    Pigment cell research, 2004, Volume: 17, Issue:3

    Topics: Buthionine Sulfoximine; Cell Line, Tumor; Cell Survival; Comet Assay; Cysteine; DNA Damage; Dose-Response Relationship, Radiation; Glutathione; Humans; Melanoma; Pigmentation; Radiation Tolerance; Radiation-Sensitizing Agents

2004
Effect of new antioxidant cysteinyl-flavanol conjugates on skin cancer cells.
    FEBS letters, 2005, Aug-15, Volume: 579, Issue:20

    Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Catechin; Cell Cycle; Cysteine; Electron Transport; Flavonoids; Free Radical Scavengers; Humans; Keratinocytes; Melanoma; Skin Neoplasms; Tumor Cells, Cultured; Vitis

2005
New cysteine derivatives with antiproliferative activity on melanoma cells.
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2006, Volume: 2, Issue:2

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cysteine; Drug Design; Enzyme Inhibitors; Fibroblasts; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Melanoma; Models, Chemical

2006
CD8 alpha coreceptor to improve TCR gene transfer to treat melanoma: down-regulation of tumor-specific production of IL-4, IL-5, and IL-10.
    Journal of immunology (Baltimore, Md. : 1950), 2006, Jul-15, Volume: 177, Issue:2

    Topics: Amino Acid Motifs; CD8 Antigens; Cell Differentiation; Cell Line; Cell Line, Tumor; Cysteine; Cytotoxicity, Immunologic; Down-Regulation; Epitopes, T-Lymphocyte; Gene Transfer Techniques; gp100 Melanoma Antigen; HLA-A2 Antigen; Humans; Interleukin-10; Interleukin-4; Interleukin-5; Melanoma; Membrane Glycoproteins; Peptide Fragments; Protein Binding; Receptors, Antigen, T-Cell, alpha-beta; Th1 Cells; Transduction, Genetic

2006
Enhanced antitumor activity of T cells engineered to express T-cell receptors with a second disulfide bond.
    Cancer research, 2007, Apr-15, Volume: 67, Issue:8

    Topics: Cysteine; Genetic Therapy; Humans; Immunotherapy, Adoptive; Jurkat Cells; Leukocytes, Mononuclear; Melanoma; Protein Engineering; Receptors, Antigen, T-Cell; T-Lymphocytes

2007
Multiple primary melanomas in a CDKN2A mutation carrier exposed to ionizing radiation.
    Archives of dermatology, 2007, Volume: 143, Issue:11

    Topics: 5' Untranslated Regions; Adult; Arginine; Cysteine; Environmental Exposure; Female; Genes, p16; Genetic Predisposition to Disease; Hair Color; Heterozygote; Humans; Melanoma; Mutation; Neoplasms, Multiple Primary; Neoplasms, Radiation-Induced; Nuclear Weapons; Receptor, Melanocortin, Type 1; Skin Neoplasms

2007
In vivo necrosis of large S-91 mouse melanomas by DL-B-phenyllactic acid plus L-cysteine.
    Life sciences, 1967, May-01, Volume: 6, Issue:9

    Topics: Animals; Cysteine; Lactates; Male; Melanoma; Mice; Neoplasms, Experimental

1967
Protein-bound dopa and 5-S-cysteinyldopa in non-melanogenic tissues.
    Acta dermato-venereologica, 1983, Volume: 63, Issue:6

    Topics: Animals; Cysteine; Cysteinyldopa; Dihydroxyphenylalanine; Free Radicals; Indoles; Melanins; Melanoma; Mice; Mice, Inbred Strains; Monophenol Monooxygenase; Protein Binding; Rats; Rats, Inbred Strains; Tyrosine

1983
Inactivation of human tyrosinase by cysteine. Protection by dopa and tyrosine.
    Acta dermato-venereologica, 1984, Volume: 64, Issue:2

    Topics: Catalase; Catechol Oxidase; Cells, Cultured; Cysteine; Humans; In Vitro Techniques; Levodopa; Melanoma; Monophenol Monooxygenase; Superoxide Dismutase; Tyrosine

1984
[Utilization of melanin precursors for experimental chemotherapy of malignant melanoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:10

    Topics: Animals; Catecholamines; Cysteamine; Cysteine; Dihydroxyphenylalanine; Melanins; Melanocytes; Melanoma; Mice; Monophenol Monooxygenase; Neoplasms, Experimental; Skin Neoplasms

1984
Effect of DOPA-loading on glutathione-dependent 5-S-cysteinyldopa genesis in melanoma cells in vitro.
    The Journal of investigative dermatology, 1982, Volume: 78, Issue:3

    Topics: Animals; Cells, Cultured; Cricetinae; Culture Media; Cysteine; Cysteinyldopa; Dihydroxyphenylalanine; Drug Synergism; Fibroblasts; Glutathione; Humans; In Vitro Techniques; Melanoma; Mice; Neoplasms, Experimental; Skin Neoplasms; Stimulation, Chemical; Tyrosine

1982
Inhibition of proliferation of cultured cells by polyamine and cysteine interaction.
    Cancer letters, 1980, Volume: 10, Issue:3

    Topics: Animals; Cell Division; Cells, Cultured; Cysteine; Drug Interactions; Melanoma; Mice; Spermidine

1980
Tyrosinase-mediated cytotoxicity of 4-substituted phenols: quantitative structure-thiol-reactivity relationships of the derived o-quinones.
    Anti-cancer drug design, 1995, Volume: 10, Issue:2

    Topics: Antineoplastic Agents; Cell Survival; Cysteine; Glutathione; Kinetics; Melanoma; Monophenol Monooxygenase; Phenols; Quinones; Spectrum Analysis; Structure-Activity Relationship

1995
The activation of type 1 and type 2 plasminogen by type I and type II tissue plasminogen activator.
    The Journal of biological chemistry, 1995, Feb-17, Volume: 270, Issue:7

    Topics: Amino Acid Sequence; Chromatography, Affinity; Cysteine; Disulfides; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Fibrinogen; Glycosylation; Humans; Isoenzymes; Kinetics; Macromolecular Substances; Melanoma; Models, Molecular; Molecular Weight; Peptide Fragments; Plasminogen; Plasminogen Activator Inhibitor 1; Protein Structure, Secondary; Tissue Plasminogen Activator; Tumor Cells, Cultured

1995
Growth inhibition and modulation of cell markers of melanoma by S-allyl cysteine.
    Oncology, 1993, Volume: 50, Issue:1

    Topics: Animals; Cell Division; Cysteine; Dose-Response Relationship, Drug; Gangliosides; Humans; Melanins; Melanoma; Mice; Thymidine; Tumor Cells, Cultured; Tumor Stem Cell Assay

1993
Modulation of 5-S-cysteinyldopa formation by tyrosinase activity and intracellular thiols in human melanoma cells.
    Melanoma research, 1996, Volume: 6, Issue:3

    Topics: Buthionine Sulfoximine; Catechols; Cell Line; Cysteine; Cysteinyldopa; Glutathione; Humans; Melanoma; Microscopy, Electron; Monophenol Monooxygenase; Tumor Cells, Cultured

1996
Cysteine deprivation promotes eumelanogenesis in human melanoma cells.
    The Journal of investigative dermatology, 1996, Volume: 107, Issue:5

    Topics: Cysteine; Glutathione; Humans; Melanins; Melanoma; Membrane Glycoproteins; Oxidoreductases; Proteins; Tumor Cells, Cultured

1996
Opposite regulation of tyrosinase and glutathione peroxidase by intracellular thiols in human melanoma cells.
    Archives of dermatological research, 1997, Volume: 289, Issue:6

    Topics: Buthionine Sulfoximine; Carmustine; Cysteine; Cystine; Glutathione; Glutathione Peroxidase; Humans; Melanins; Melanoma; Monophenol Monooxygenase; Oxidative Stress; Sodium Selenite; Sulfhydryl Compounds; Tumor Cells, Cultured

1997
Effects on interstitial glutathione, cysteine and 5-S-cysteinyldopa of buthionine sulphoximine in human melanoma transplants.
    Melanoma research, 1997, Volume: 7, Issue:4

    Topics: Acetylcysteine; Animals; Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Cysteine; Cysteinyldopa; Drug Interactions; Enzyme Inhibitors; Glutathione; Humans; Melanoma; Mice; Mice, Inbred BALB C; Mice, Nude; Microdialysis; Neoplasm Transplantation; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines

1997
Evidence for protein dolichylation.
    FEBS letters, 1997, Oct-27, Volume: 416, Issue:3

    Topics: Autoradiography; Chromatography, High Pressure Liquid; Colonic Neoplasms; Cysteine; Dolichols; Hepatoblastoma; Humans; Liver Neoplasms; Melanoma; Mevalonic Acid; Neoplasm Proteins; Peptide Fragments; Protein Prenylation; Sulfur Radioisotopes; Tritium; Tumor Cells, Cultured

1997
Human melanoma patients recognize an HLA-A1-restricted CTL epitope from tyrosinase containing two cysteine residues: implications for tumor vaccine development.
    Journal of immunology (Baltimore, Md. : 1950), 1998, Mar-01, Volume: 160, Issue:5

    Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Cancer Vaccines; Cysteine; Cytotoxicity, Immunologic; HLA-A1 Antigen; Humans; Immunodominant Epitopes; Melanoma; Monophenol Monooxygenase; Peptide Fragments; Serine; T-Lymphocytes, Cytotoxic; Tumor Cells, Cultured

1998
[Development of targeted chemoradiotherapy for malignant melanoma by exploitation of metabolic pathway].
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1998, Volume: 73, Issue:2

    Topics: Animals; Antineoplastic Agents; Cysteamine; Cysteine; DNA Damage; Humans; Melanins; Melanoma; Mice; Monophenol Monooxygenase; Oxidative Stress; Phenols; Skin Neoplasms; Substrate Specificity; Tumor Cells, Cultured; Tyrosine

1998
Several noncontiguous domains of CDK4 are involved in binding to the P16 tumor suppressor protein.
    Biochemical and biophysical research communications, 1998, Aug-19, Volume: 249, Issue:2

    Topics: Arginine; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinases; Cysteine; Glutathione Transferase; Humans; Melanoma; Mutagenesis, Site-Directed; Mutation; Proto-Oncogene Proteins; Recombinant Fusion Proteins; Structure-Activity Relationship; Tyrosine

1998
Identification of new melanoma epitopes on melanosomal proteins recognized by tumor infiltrating T lymphocytes restricted by HLA-A1, -A2, and -A3 alleles.
    Journal of immunology (Baltimore, Md. : 1950), 1998, Dec-15, Volume: 161, Issue:12

    Topics: Adult; Alleles; Amino Acid Sequence; Amino Acid Substitution; Antigens, Neoplasm; Cysteine; DNA, Complementary; DNA, Neoplasm; Epitopes; Female; gp100 Melanoma Antigen; HLA-A1 Antigen; HLA-A2 Antigen; HLA-A3 Antigen; Humans; Lymphocytes, Tumor-Infiltrating; Male; Melanoma; Membrane Glycoproteins; Molecular Sequence Data; Monophenol Monooxygenase; Neoplasm Proteins; Oxidation-Reduction; Peptide Fragments; Sequence Alignment; Sequence Homology, Amino Acid; T-Lymphocytes, Cytotoxic; Tumor Cells, Cultured

1998
Co-regulation of melanin precursors and tyrosinase in human pigment cells: roles of cysteine and glutathione.
    Cellular and molecular biology (Noisy-le-Grand, France), 1999, Volume: 45, Issue:7

    Topics: Buthionine Sulfoximine; Cells, Cultured; Cysteine; Cysteinyldopa; Dihydroxyphenylalanine; Glutathione; Humans; Infant, Newborn; Male; Melanins; Melanocytes; Melanoma; Melanosomes; Monophenol Monooxygenase; Neoplasm Proteins; Skin Neoplasms; Tumor Cells, Cultured; Tyrosine

1999
Comparison of N-acetylcysteine and l-2-oxothiazolidine-4-carboxylate as cysteine deliverers and glutathione precursors in human malignant melanoma transplants in mice.
    Cancer chemotherapy and pharmacology, 2000, Volume: 45, Issue:3

    Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Cysteine; Cysteinyldopa; Enzyme Inhibitors; Glutathione; Humans; Melanoma; Melanoma, Experimental; Mice; Mice, Nude; Microdialysis; Neoplasm Transplantation; Protein Precursors; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Transplantation, Heterologous; Tumor Cells, Cultured

2000
Tyrosinase-mediated formation of a reactive quinone from the depigmenting agents, 4-tert-butylphenol and 4-tert-butylcatechol.
    Pigment cell research, 2000, Volume: 13, Issue:1

    Topics: Agaricales; Antioxidants; Catechols; Chromatography, High Pressure Liquid; Cysteine; Glutathione; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Magnetic Resonance Spectroscopy; Melanocytes; Melanoma; Monophenol Monooxygenase; Oxidation-Reduction; Phenols; Pigmentation; Pigments, Biological; Quinones; Tumor Cells, Cultured

2000
Genotype-phenotype relationships in U.S. melanoma-prone families with CDKN2A and CDK4 mutations.
    Journal of the National Cancer Institute, 2000, Jun-21, Volume: 92, Issue:12

    Topics: Adolescent; Adult; Age Factors; Aged; Arginine; Aspartic Acid; Cyclin-Dependent Kinases; Cysteine; Genes, p16; Genotype; Germ-Line Mutation; Glycine; Haplotypes; Humans; Melanoma; Middle Aged; Nevus; Pancreatic Neoplasms; Phenotype; Skin Neoplasms; Statistics, Nonparametric; Tryptophan; United States; Valine

2000
Identification of NY-ESO-1 peptide analogues capable of improved stimulation of tumor-reactive CTL.
    Journal of immunology (Baltimore, Md. : 1950), 2000, Jul-15, Volume: 165, Issue:2

    Topics: Amino Acid Substitution; Antigen Presentation; Antigens, Neoplasm; Cysteine; Cytotoxicity, Immunologic; Epitopes, T-Lymphocyte; HLA-A2 Antigen; Humans; Intracellular Fluid; Lymphocyte Activation; Melanoma; Membrane Proteins; Peptide Fragments; Protein Binding; Proteins; T-Lymphocytes, Cytotoxic; Tumor Cells, Cultured

2000
Extra-cellular thiol metabolism in clones of human metastatic melanoma with different gamma-glutamyl transpeptidase expression: implications for cell response to platinum-based drugs.
    International journal of cancer, 2002, Feb-20, Volume: 97, Issue:6

    Topics: Antineoplastic Agents; Chromatography, High Pressure Liquid; Cysteine; Disulfides; gamma-Glutamyltransferase; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Humans; Hydrogen Peroxide; Melanoma; Organoplatinum Compounds; Oxidants; Skin Neoplasms; Tumor Cells, Cultured

2002
Absence of gamma-interferon-inducible lysosomal thiol reductase in melanomas disrupts T cell recognition of select immunodominant epitopes.
    The Journal of experimental medicine, 2002, May-20, Volume: 195, Issue:10

    Topics: Antigen-Presenting Cells; CD4-Positive T-Lymphocytes; Cell Division; Cysteine; Epitopes, T-Lymphocyte; Humans; Immunodominant Epitopes; Interferon-gamma; Mass Spectrometry; Melanoma; Oxidation-Reduction; Oxidoreductases; Oxidoreductases Acting on Sulfur Group Donors; Peptide Fragments; T-Lymphocytes; Transfection; Tumor Cells, Cultured

2002
Formation of cysteinyldopa from glutathionedopa in melanoma.
    Acta dermato-venereologica, 1975, Volume: 55, Issue:1

    Topics: Animals; Cysteine; Depression, Chemical; Dihydroxyphenylalanine; Glutathione; Guinea Pigs; Humans; Kidney; Lung; Lung Neoplasms; Melanoma; Mice; Neoplasm Metastasis; Skin Neoplasms; Stimulation, Chemical

1975
5-S-cysteinyldopa in the plasma of melanoma patients and the renal clearance of this amino acid.
    Acta dermato-venereologica, 1975, Volume: 55, Issue:1

    Topics: Adult; Breast Neoplasms; Cysteine; Dihydroxyphenylalanine; Humans; Liver Neoplasms; Lung Neoplasms; Male; Melanoma; Neoplasm Metastasis; Skin Neoplasms

1975
Collagenolytic activities of cultured human malignant melanoma cells.
    Journal of biochemistry, 1978, Volume: 84, Issue:5

    Topics: Adult; Cells, Cultured; Cysteine; Edetic Acid; Humans; Male; Melanoma; Microbial Collagenase; Middle Aged; Tropocollagen

1978
Differentiation of melanocytes in cultures of primary malignant melanoma indicated by 5-S-cysteinyldopa formation.
    Journal of the National Cancer Institute, 1975, Volume: 55, Issue:6

    Topics: Cell Differentiation; Cells, Cultured; Cysteine; Dihydroxyphenylalanine; Humans; Melanocytes; Melanoma

1975
[Urinary 5-S-cysteinyldopa levels in patients with malignant melanoma. Preliminary results].
    La Revue du praticien, 1975, Volume: 25, Issue:51

    Topics: Creatinine; Cysteine; Dihydroxyphenylalanine; Melanoma; Neoplasm Metastasis; Skin Neoplasms

1975
[Chemical diagnosis of melanoma].
    Lakartidningen, 1976, Feb-11, Volume: 73, Issue:7

    Topics: Cysteine; Dihydroxyphenylalanine; Humans; Melanoma; Neoplasm Metastasis; Skin Neoplasms

1976
Tyrosine transport in a human melanoma cell line as a basis for selective transport of cytotoxic analogues.
    The Biochemical journal, 1991, Dec-15, Volume: 280 ( Pt 3)

    Topics: Amino Acids; Amino Acids, Cyclic; Biological Transport, Active; Cysteine; Drug Delivery Systems; Evaluation Studies as Topic; Humans; Kinetics; Melanoma; Sodium; Tumor Cells, Cultured; Tyrosine

1991
Glutathione in human melanoma cells. Effects of cysteine, cysteine esters and glutathione isopropyl ester.
    Journal of dermatological science, 1990, Volume: 1, Issue:1

    Topics: Acetylcysteine; Cysteine; Expectorants; Glutathione; Humans; Melanoma; Skin Neoplasms; Tumor Cells, Cultured

1990
The synthesis of 4-S-cysteinyl-[U-14C]phenol, an experimental antimelanoma agent.
    International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes, 1989, Volume: 40, Issue:6

    Topics: Antineoplastic Agents; Cysteine; Melanoma

1989
Modulation of glutathione level in cultured human melanoma cells.
    Acta dermato-venereologica, 1989, Volume: 69, Issue:2

    Topics: Antimetabolites; Buthionine Sulfoximine; Cell Line; Cell Survival; Cysteine; Glutathione; Humans; Melanoma; Methionine Sulfoximine; Tumor Cells, Cultured; Vitamin K

1989
Site-specific mutagenesis of the human interleukin-1 beta gene: structure-function analysis of the cysteine residues.
    Biochemical and biophysical research communications, 1988, Feb-15, Volume: 150, Issue:3

    Topics: Codon; Cysteine; DNA Restriction Enzymes; DNA, Recombinant; DNA, Single-Stranded; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Humans; Interleukin-1; Melanoma; Molecular Weight; Mutation; Plasmids; Structure-Activity Relationship; Tumor Cells, Cultured

1988
The role of sulfhydryl compounds in mammalian melanogenesis: the effect of cysteine and glutathione upon tyrosinase and the intermediates of the pathway.
    Biochimica et biophysica acta, 1988, Nov-17, Volume: 967, Issue:2

    Topics: Animals; Catechol Oxidase; Cysteine; Glutathione; Melanins; Melanoma; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Monophenol Monooxygenase; Tyrosine 3-Monooxygenase

1988
Characterization of the human melanoma nerve growth factor receptor.
    The Journal of biological chemistry, 1985, Jul-05, Volume: 260, Issue:13

    Topics: Antibodies, Monoclonal; Cell Line; Cysteine; Electrophoresis, Polyacrylamide Gel; Glucosamine; Humans; Melanoma; Mercaptoethanol; Molecular Weight; Phosphorylation; Protein Processing, Post-Translational; Receptors, Cell Surface; Receptors, Nerve Growth Factor

1985
The killing effects of 4-S-cysteinylcatechol and analogues on human melanoma cells.
    British journal of cancer, 1988, Volume: 58, Issue:6

    Topics: Antineoplastic Agents; Cell Survival; Chemical Phenomena; Chemistry; Cysteine; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Female; Humans; Melanoma; Tumor Cells, Cultured

1988
Specific incorporation of 4-S-cysteinylphenol into human melanoma cells.
    The Journal of investigative dermatology, 1988, Volume: 90, Issue:5

    Topics: Autoradiography; Cysteine; Humans; Melanoma; Microscopy, Electron; Time Factors; Tumor Cells, Cultured

1988
The cytotoxicity of cysteinylcatechols and related compounds to human melanoma cells in vitro.
    The Journal of investigative dermatology, 1987, Volume: 88, Issue:5

    Topics: Antineoplastic Agents; Catechols; Cell Division; Cell Line; Cell Survival; Cysteine; Dose-Response Relationship, Drug; Humans; Levodopa; Melanoma; Phenols; Time Factors

1987
Fluorometry of a DOPA peptide and its thioether.
    Acta dermato-venereologica, 1971, Volume: 51, Issue:3

    Topics: Carbon Isotopes; Catechol Oxidase; Catechols; Chromatography, Paper; Cysteine; Dihydroxyphenylalanine; Dipeptides; Ethers; Fluorescence; Fluorometry; Melanoma; Peptides; Phenylalanine; Pigments, Biological; Spectrophotometry; Sulfhydryl Reagents; Sulfur; Tyrosine

1971
Dopa and 5-S-cysteinyldopa in malignant melanoma in Ugandan Africans.
    Acta dermato-venereologica, 1974, Volume: 54, Issue:1

    Topics: Adult; Aged; Black People; Cysteine; Dihydroxyphenylalanine; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Skin Neoplasms; Spectrophotometry; Uganda

1974
5-S-cysteinyldopa in melanomas of Caucasians.
    Acta dermato-venereologica, 1974, Volume: 54, Issue:1

    Topics: Adult; Aged; Chromatography; Cysteine; Dihydroxyphenylalanine; Female; Fluorometry; Hair; Humans; Melanoma; Middle Aged; Neoplasm Metastasis; Pigmentation; Skin Neoplasms; White People

1974
Study of S91 mouse melanomas by electron paramagnetic resonance spectroscopy and tissue culture. I. The effect of cysteine on blue light signals and on growth in vitro.
    Journal of the National Cancer Institute, 1966, Volume: 37, Issue:2

    Topics: Animals; Culture Techniques; Cysteine; Electron Spin Resonance Spectroscopy; Humans; Melanoma; Mice; Neoplasms, Experimental

1966
The melanocyte illuminated.
    Transactions of the St. John's Hospital Dermatological Society, 1974, Volume: 60, Issue:2

    Topics: Animals; Cysteine; Dihydroxyphenylalanine; Histocytochemistry; Humans; Melanocytes; Melanoma

1974
Determination of 5-S-cysteinyldopa in melanomas with a fluorimetric method.
    The Yale journal of biology and medicine, 1973, Volume: 46, Issue:5

    Topics: Animals; Black People; Cysteine; Dihydroxyphenylalanine; Dopamine; Fluorometry; Guinea Pigs; Hair; Humans; Melanoma; Mice; Neoplasm Metastasis; Pigmentation; Skin; White People

1973
Identification of melanoma cells by formaldehyde-induced fluorescence.
    Cancer, 1974, Volume: 33, Issue:3

    Topics: Adenocarcinoma; Cell Line; Culture Techniques; Cysteine; Dopamine; Fluorescence; Formaldehyde; HeLa Cells; Humans; Melanoma; Tyrosine; Ultraviolet Rays

1974
In vitro growth inhibition of S-91 mouse melanomas by tyrosinase substrate analogs with and without L-cysteine.
    Cancer research, 1967, Volume: 27, Issue:10

    Topics: Animals; Catechol Oxidase; Chemical Phenomena; Chemistry; Cysteine; In Vitro Techniques; Melanoma; Mice; Neoplasms, Experimental; Phenylalanine; Tyrosine

1967
Inhibition of S-91 mouse melanoma metastases and growth by D-penicillamine.
    Laboratory investigation; a journal of technical methods and pathology, 1969, Volume: 21, Issue:5

    Topics: Animals; Catechol Oxidase; Copper; Cysteine; Melanoma; Mice; Neoplasm Metastasis; Penicillamine; Tyrosine

1969
Unusual effects of reducing agents on 0-diphenoloxidase of Mycobacterium leprae.
    Journal of bacteriology, 1971, Volume: 107, Issue:3

    Topics: Animals; Ascorbic Acid; Azides; Basidiomycota; Catechol Oxidase; Cell-Free System; Cyanides; Cysteine; Cystine; Dihydroxyphenylalanine; Glutathione; Humans; Manometry; Melanins; Melanoma; Mice; Mycobacterium leprae; Oxidation-Reduction; Quinones; Skin; Species Specificity; Spectrophotometry; Spleen; Stereoisomerism; Tissue Extracts; Tyrosine

1971