cysteine and MEA 2a

cysteine has been researched along with MEA 2a in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's13 (40.63)18.2507
2000's10 (31.25)29.6817
2010's5 (15.63)24.3611
2020's4 (12.50)2.80

Authors

AuthorsStudies
Craven, GB; De Castro Ribeiro, O; Goldman, A; Haapanen, O; Liu, Y; Muench, SP; Sharma, V1
Araki, M; Ikegami, M; Kanno, SI; Kohno, T; Kohsaka, S; Mano, H; Matsumoto, S; Miyoshi, K; Nakaoku, T; Okamoto, A; Okuno, Y; Otsuka, A; Sagae, Y; Sekijima, M; Tabata, J; Ui, A; Yasui, A; Yoshino, R1
Goldman, A; Liu, Y; Ribeiro, OC; Robinson, J1
Biarnés, J; de la Bellacasa, JP; Oriola, J; Paniello, B; Sanchez, A1
Andreou, E; Cariolou, MA; Christophidou-Anastasiadou, V; Christopoulos, G; Fanis, P; Frangos, S; Kleanthous, M; Manoli, P; Mavrommatis, M; Neocleous, V; Nicolaou, S; Phylactou, LA; Skordis, N; Spanou-Aristidou, E; Tanteles, GA1
Camacho, CP; Cerutti, JM; Delcelo, R; Dias-da-Silva, MR; França, MI; Hoff, AO; Kasamatsu, TS; Lindsey, SC; Machado, AL; Maciel, RM; Salim, CP; Signorini, PS; Valente, FO1
Boutati, E; Economopoulos, T; Hadjidakis, D; Kamakari, S; Panayiotides, IG; Peppa, M; Peros, G; Pikounis, V; Raptis, SA1
Mukherjee, S; Zakalik, D1
Goto, Y; Hossain, K; Iida, M; Kato, M; Kumasaka, MY; Ohgami, N; Takeda, K; Yajima, I1
Barollo, S; Mian, C; Opocher, G; Sartorato, P; Zane, M1
Balsalobre, MD; Carbonell, P; Glower, G; Parrilla, P; Pomares, F; Ríos, A; Rodríguez, GJ; Sola, J; Tébar, J; Torregrosa, NM1
Ezabella, MC; Krieger, JE; Nunes, AB; Pereira, AC; Toledo, SP1
Carlomagno, MS; Cerchia, L; de Franciscis, V; Libri, D1
Altaner, C; Altanerova, V; Breza, J; Kostalova, L; Poturnajova, M1
Fitze, G1
Abrescia, C; Ibáñez, CF; Kjaer, S; Kurokawa, K; Perrinjaquet, M1
Becherini, L; Cantini, G; Ercolino, T; Gaglianò, MS; Lombardi, A; Luconi, M; Mannelli, M; Piscitelli, E; Serio, M1
Eng, C; Gardner, E; Healey, CS; Kwok, JB; Mulligan, LM; Ponder, BA; Ponder, MA1
Besser, GM; Chew, SL; Clark, AJ; Jain, A; Lavender, P; Ross, RJ; Wass, JA; Weber, A1
Gagel, RF1
Komminoth, P1
Clayton, D; Cote, G; Eng, C; Fink, M; Frank-Raue, K; Gagel, RF; Hendy, GN; Komminoth, P; Lenoir, G; Lips, CJ; Marsh, DJ; Mulligan, LM; Niederle, B; Nishisho, I; Noll, WW; Nordenskjöld, M; Pacini, F; Raue, F; Robinson, BG; Romei, C; Schuffenecker, I; Takai, SI; van Amstel, HK; Xue, F; Zedenius, J1
Blijham, GH; de Valk, IA; Höppener, JW; Jansen-Schillhorn van Veen, JM; Landsvater, RM; Lips, CJ; Moers, AM; Schaap, C; van Amstel, HK; Vroom, TM1
Höppner, W; Ritter, MM1
Betsos, N; Camera, G; Celli, I; Claudiani, F; Romeo, G; Seri, M1
Asai, N; Ito, S; Iwashita, T; Iwata, Y; Murakami, H; Sobue, G; Takahashi, M1
Antiñolo, G; Astorga, R; Borrego, S; Conde, AF; Japón, MA; Navarro, E; Sánchez, B1
Brabant, G; Dralle, H; Höppner, W1
Antiñolo, G; Borrego, S; Eng, C; Navarro, E; Sáez, ME; Sánchez, B1
Attié, T; Billaud, M; Chappuis-Flament, S; De Vita, G; Fusco, A; Lenoir, GM; Pasini, A; Santoro, M; Ségouffin-Cariou, C1
Akhand, AA; Du, J; Hossain, K; Iwashita, T; Kato, M; Kawamoto, Y; Liu, W; Nakashima, I; Oh, C; Suzuki, H; Takahashi, M; Takeda, K; Takeuchi, K; Wu, J; Yoshihara, M1
Blanes, A; de Miguel, M; Diaz-Cano, SJ; Tashjian, R; Wolfe, HJ1

Reviews

6 review(s) available for cysteine and MEA 2a

ArticleYear
Multiple endocrine neoplasia type 2A in two families with the familial medullary thyroid carcinoma associated G533C mutation of the RET proto-oncogene.
    European journal of endocrinology, 2008, Volume: 159, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Carcinoma, Medullary; Cysteine; Female; Glycine; Humans; Male; Middle Aged; Multiple Endocrine Neoplasia Type 2a; Pedigree; Phenotype; Point Mutation; Proto-Oncogene Mas; Proto-Oncogene Proteins c-ret; Syndrome; Thyroid Neoplasms; Young Adult

2008
RET codon 804 mutations in multiple endocrine neoplasia 2: genotype-phenotype correlations and implications in clinical management.
    Clinical genetics, 2011, Volume: 79, Issue:1

    Topics: Adolescent; Adult; Child; Child, Preschool; Codon; Cysteine; Female; Genetic Association Studies; Germ-Line Mutation; Humans; Infant; Male; Middle Aged; Multiple Endocrine Neoplasia Type 2a; Penetrance; Point Mutation; Proto-Oncogene Mas; Proto-Oncogene Proteins c-ret; Proto-Oncogenes; Thyroid Neoplasms; Young Adult

2011
RET codon 609 mutations: a contribution for better clinical managing.
    Clinics (Sao Paulo, Brazil), 2012, Volume: 67 Suppl 1

    Topics: Carcinoma, Medullary; Carcinoma, Neuroendocrine; Codon; Cysteine; Genetic Association Studies; Germ-Line Mutation; Humans; Hyperparathyroidism; Italy; Multiple Endocrine Neoplasia Type 2a; Pedigree; Proto-Oncogene Mas; Proto-Oncogene Proteins c-ret; Serine; Thyroid Neoplasms

2012
Management of patients with hereditary medullary thyroid carcinoma.
    European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie, 2004, Volume: 14, Issue:6

    Topics: Carcinoma, Medullary; Chromosome Mapping; Cysteine; Genetic Counseling; Hirschsprung Disease; Humans; Multiple Endocrine Neoplasia Type 2a; Mutation, Missense; Oncogene Proteins; Proto-Oncogene Mas; Proto-Oncogene Proteins c-ret; Receptor Protein-Tyrosine Kinases; Risk Assessment; Signal Transduction; Thyroid Neoplasms; Thyroidectomy

2004
Putting the bits and pieces of the RET proto-oncogene puzzle together.
    Bone, 1995, Volume: 17, Issue:2 Suppl

    Topics: Amino Acid Sequence; Base Sequence; Carcinoma; Cysteine; Drosophila Proteins; Gene Expression; Hirschsprung Disease; Humans; Male; Molecular Sequence Data; Multiple Endocrine Neoplasia Type 2a; Multiple Endocrine Neoplasia Type 2b; Phosphorylation; Point Mutation; Protein-Tyrosine Kinases; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Receptor Protein-Tyrosine Kinases; Thyroid Neoplasms

1995
Molecular mechanism of activation and superactivation of Ret tyrosine kinases by ultraviolet light irradiation.
    Antioxidants & redox signaling, 2000,Winter, Volume: 2, Issue:4

    Topics: Amino Acid Sequence; Animals; Cysteine; Dimerization; Drosophila Proteins; Enzyme Activation; Humans; Models, Biological; Multiple Endocrine Neoplasia Type 2a; Mutation; Protein Structure, Quaternary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Receptor Protein-Tyrosine Kinases; Ultraviolet Rays

2000

Other Studies

26 other study(ies) available for cysteine and MEA 2a

ArticleYear
Unexpected structures formed by the kinase RET C634R mutant extracellular domain suggest potential oncogenic mechanisms in MEN2A.
    The Journal of biological chemistry, 2022, Volume: 298, Issue:10

    Topics: Arginine; Carcinogenesis; Cysteine; Humans; Ligands; Multiple Endocrine Neoplasia Type 2a; Point Mutation; Protein Domains; Protein Multimerization; Proto-Oncogene Proteins c-ret

2022
Novel Calcium-Binding Ablating Mutations Induce Constitutive RET Activity and Drive Tumorigenesis.
    Cancer research, 2022, 10-17, Volume: 82, Issue:20

    Topics: Calcium; Calmodulin; Carcinogenesis; Cysteine; Disulfides; Drosophila Proteins; Humans; Ligands; Multiple Endocrine Neoplasia Type 2a; Mutation; Neoplasms; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret

2022
Expression and purification of the extracellular domain of wild-type humanRET and the dimeric oncogenic mutant C634R.
    International journal of biological macromolecules, 2020, Dec-01, Volume: 164

    Topics: Animals; Carcinogenesis; Cell Line; Cysteine; Disulfides; HEK293 Cells; Hirschsprung Disease; Humans; Mammals; Multiple Endocrine Neoplasia Type 2a; Mutation; Parkinson Disease; Protein Domains; Proto-Oncogene Proteins c-ret; Recombinant Proteins; Signal Transduction

2020
A novel germline variant in RET gene resulting in an additional cysteine in a family with familial medullary thyroid carcinoma.
    Familial cancer, 2021, Volume: 20, Issue:3

    Topics: Adult; Aged; Carcinoma, Medullary; Cysteine; Female; Germ-Line Mutation; Heterozygote; Humans; Male; Middle Aged; Multiple Endocrine Neoplasia Type 2a; Pedigree; Phenotype; Prophylactic Surgical Procedures; Proto-Oncogene Proteins c-ret; Thyroid Neoplasms; Thyroidectomy

2021
Multiple endocrine neoplasia 2 in Cyprus: evidence for a founder effect.
    Journal of endocrinological investigation, 2018, Volume: 41, Issue:10

    Topics: Adult; Arginine; Carcinoma, Medullary; Cohort Studies; Cyprus; Cysteine; Female; Founder Effect; Humans; Male; Middle Aged; Multiple Endocrine Neoplasia Type 2a; Pedigree; Proto-Oncogene Mas; Proto-Oncogene Proteins c-ret; Thyroid Neoplasms

2018
A ten-year clinical update of a large RET p.Gly533Cys kindred with medullary thyroid carcinoma emphasizes the need for an individualized assessment of affected relatives.
    Clinical endocrinology, 2014, Volume: 80, Issue:2

    Topics: Adolescent; Adult; Aged; Amino Acid Substitution; Calcitonin; Carcinoembryonic Antigen; Carcinoma, Neuroendocrine; Child; Child, Preschool; Cysteine; Family Health; Female; Follow-Up Studies; Glycine; Humans; Male; Metanephrine; Middle Aged; Multiple Endocrine Neoplasia Type 2a; Mutation; Pedigree; Proto-Oncogene Proteins c-ret; Thyroid Neoplasms; Thyroidectomy; Time Factors; Young Adult

2014
L-cysteine as a regulator for arsenic-mediated cancer-promoting and anti-cancer effects.
    Toxicology in vitro : an international journal published in association with BIBRA, 2011, Volume: 25, Issue:3

    Topics: Animals; Anticarcinogenic Agents; Arsenites; Carcinogens, Environmental; Cell Survival; Cysteine; Drug Interactions; Enzyme Inhibitors; Matrix Metalloproteinase 2; Mice; Multiple Endocrine Neoplasia Type 2a; NIH 3T3 Cells; Poly(ADP-ribose) Polymerases; Sodium Compounds; Transfection

2011
Prophylactic thyroidectomy in MEN 2A syndrome: experience in a single center.
    Journal of the American College of Surgeons, 2002, Volume: 195, Issue:2

    Topics: Adolescent; Adult; Calcitonin; Child; Child, Preschool; Cysteine; Drosophila Proteins; Female; Humans; Infant; Male; Multiple Endocrine Neoplasia Type 2a; Mutation; Neoplasm Recurrence, Local; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Receptor Protein-Tyrosine Kinases; Thyroid Function Tests; Thyroid Neoplasms; Thyroidectomy; Tyrosine

2002
A novel Val648Ile substitution in RET protooncogene observed in a Cys634Arg multiple endocrine neoplasia type 2A kindred presenting with an adrenocorticotropin-producing pheochromocytoma.
    The Journal of clinical endocrinology and metabolism, 2002, Volume: 87, Issue:12

    Topics: Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Amino Acid Substitution; Arginine; Child; Cysteine; Drosophila Proteins; Female; Humans; Isoleucine; Male; Multiple Endocrine Neoplasia Type 2a; Pedigree; Pheochromocytoma; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Receptor Protein-Tyrosine Kinases; Valine

2002
The soluble ectodomain of RetC634Y inhibits both the wild-type and the constitutively active Ret.
    The Biochemical journal, 2003, Jun-15, Volume: 372, Issue:Pt 3

    Topics: Amino Acid Substitution; Animals; Binding, Competitive; Cells, Cultured; Cysteine; Dimerization; Glial Cell Line-Derived Neurotrophic Factor; Glial Cell Line-Derived Neurotrophic Factor Receptors; Glycosylation; Humans; Ligands; Multiple Endocrine Neoplasia Type 2a; Nerve Growth Factors; PC12 Cells; Protein Structure, Tertiary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Rats; Receptor Protein-Tyrosine Kinases; Recombinant Proteins; Solubility; Tyrosine

2003
Novel germline mutation in the transmembrane region of RET gene close to Cys634Ser mutation associated with MEN 2A syndrome.
    Journal of molecular medicine (Berlin, Germany), 2005, Volume: 83, Issue:4

    Topics: Adrenal Gland Neoplasms; Carcinoma, Medullary; Cysteine; Exons; Female; Gene Frequency; Genetic Linkage; Germ-Line Mutation; Humans; Male; Multiple Endocrine Neoplasia Type 2a; Oncogene Proteins; Pedigree; Pheochromocytoma; Proto-Oncogene Proteins c-ret; Receptor Protein-Tyrosine Kinases; Serine; Thyroid Neoplasms

2005
Self-association of the transmembrane domain of RET underlies oncogenic activation by MEN2A mutations.
    Oncogene, 2006, Nov-09, Volume: 25, Issue:53

    Topics: Alanine; Amino Acid Sequence; Animals; Cell Membrane; Cysteine; Dimerization; Disulfides; Drosophila melanogaster; Drosophila Proteins; Gene Expression; Glial Cell Line-Derived Neurotrophic Factor; Humans; Molecular Sequence Data; Multiple Endocrine Neoplasia Type 2a; Mutation; Protein Binding; Proto-Oncogene Proteins c-ret; Sequence Alignment; Sequence Homology, Amino Acid; Thyroid Neoplasms

2006
The Y606C RET mutation causes a receptor gain of function.
    Clinical endocrinology, 2008, Volume: 69, Issue:2

    Topics: Amino Acid Substitution; Animals; Base Sequence; Carcinoma, Medullary; Cysteine; Female; Germ-Line Mutation; Humans; Mice; Middle Aged; Multiple Endocrine Neoplasia Type 2a; NIH 3T3 Cells; Proto-Oncogene Proteins c-ret; Thyroid Neoplasms; Tyrosine

2008
Haplotype analysis of MEN 2 mutations.
    Human molecular genetics, 1994, Volume: 3, Issue:10

    Topics: Amino Acid Sequence; Arginine; Chromosome Mapping; Chromosomes, Human, Pair 10; Codon; Cysteine; Drosophila Proteins; Haplotypes; Humans; Multiple Endocrine Neoplasia Type 2a; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Proto-Oncogenes; Receptor Protein-Tyrosine Kinases; Restriction Mapping

1994
Absence of mutations in the MEN2A region of the ret proto-oncogene in non-MEN 2A phaeochromocytomas.
    Clinical endocrinology, 1995, Volume: 42, Issue:1

    Topics: Adrenal Gland Neoplasms; Arginine; Base Sequence; Codon; Cysteine; Drosophila Proteins; Humans; Molecular Sequence Data; Multiple Endocrine Neoplasia Type 2a; Paraganglioma; Pheochromocytoma; Point Mutation; Polymerase Chain Reaction; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Proto-Oncogenes; Receptor Protein-Tyrosine Kinases

1995
Rudolf-Virchow-Preis 1995. The role of RET proto-oncogene mutation analysis in the diagnosis of multiple endocrine neoplasia type 2 (MEN 2) gene carriers and in the discrimination of sporadic and familial medullary thyroid carcinomas and pheochromocytomas
    Verhandlungen der Deutschen Gesellschaft fur Pathologie, 1995, Volume: 79

    Topics: Adrenal Gland Neoplasms; Awards and Prizes; Codon; Cysteine; Diagnosis, Differential; Drosophila Proteins; Genetic Carrier Screening; Humans; Hyperplasia; Methionine; Multiple Endocrine Neoplasia Type 2a; Multiple Endocrine Neoplasia Type 2b; Pathology; Pheochromocytoma; Point Mutation; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Proto-Oncogenes; Receptor Protein-Tyrosine Kinases; Threonine; Thyroid Neoplasms

1995
The relationship between specific RET proto-oncogene mutations and disease phenotype in multiple endocrine neoplasia type 2. International RET mutation consortium analysis.
    JAMA, 1996, Nov-20, Volume: 276, Issue:19

    Topics: Carcinoma, Medullary; Codon; Cysteine; Drosophila Proteins; Hirschsprung Disease; Humans; Hyperparathyroidism; Multiple Endocrine Neoplasia Type 2a; Mutation; Phenotype; Pheochromocytoma; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Receptor Protein-Tyrosine Kinases; Thyroid Neoplasms

1996
Familial medullary thyroid carcinoma: not a distinct entity? Genotype-phenotype correlation in a large family.
    The American journal of medicine, 1996, Volume: 101, Issue:6

    Topics: Adrenal Gland Neoplasms; Adult; Aged; Carcinoma, Medullary; Cysteine; DNA Probes; Drosophila Proteins; Female; Genotype; Germ-Line Mutation; Humans; Hyperparathyroidism; Male; Middle Aged; Multiple Endocrine Neoplasia Type 2a; Pedigree; Phenotype; Pheochromocytoma; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Receptor Protein-Tyrosine Kinases; Thyroid Neoplasms

1996
A duplication of 12 bp in the critical cysteine rich domain of the RET proto-oncogene results in a distinct phenotype of multiple endocrine neoplasia type 2A.
    Human molecular genetics, 1997, Volume: 6, Issue:4

    Topics: Alleles; Cysteine; Drosophila Proteins; Electrophoresis, Polyacrylamide Gel; Exons; Female; Humans; Hypercalcemia; Hyperplasia; Male; Multiple Endocrine Neoplasia Type 2a; Mutation; Parathyroid Glands; Pedigree; Phenotype; Polymerase Chain Reaction; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Receptor Protein-Tyrosine Kinases; Repetitive Sequences, Nucleic Acid; Sequence Analysis

1997
A Cys634Gly substitution of the RET proto-oncogene in a family with recurrence of multiple endocrine neoplasia type 2A and cutaneous lichen amyloidosis.
    Clinical genetics, 1997, Volume: 51, Issue:2

    Topics: Adolescent; Adult; Amyloidosis; Child; Cysteine; Deoxyribonucleases, Type II Site-Specific; Drosophila Proteins; Female; Glycine; Humans; Lichenoid Eruptions; Male; Middle Aged; Multiple Endocrine Neoplasia Type 2a; Mutation; Pedigree; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Receptor Protein-Tyrosine Kinases; Sequence Analysis, DNA

1997
Biological properties of Ret with cysteine mutations correlate with multiple endocrine neoplasia type 2A, familial medullary thyroid carcinoma, and Hirschsprung's disease phenotype.
    Cancer research, 1997, Jul-15, Volume: 57, Issue:14

    Topics: 3T3 Cells; Animals; Carcinoma, Medullary; Cysteine; Drosophila Proteins; Hirschsprung Disease; Humans; Mice; Molecular Weight; Multiple Endocrine Neoplasia Type 2a; Mutation; Phenotype; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Proto-Oncogenes; Receptor Protein-Tyrosine Kinases; Thyroid Neoplasms

1997
Cys 634 mutations in the RET proto-oncogene in Spanish families affected by MEN 2A.
    Human mutation, 1998, Volume: Suppl 1

    Topics: Amino Acid Substitution; Cysteine; DNA; DNA Mutational Analysis; Drosophila Proteins; Family Health; Female; Humans; Male; Multiple Endocrine Neoplasia Type 2a; Mutation; Mutation, Missense; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Receptor Protein-Tyrosine Kinases; Spain

1998
Duplication of 9 base pairs in the critical cysteine-rich domain of the RET proto-oncogene causes multiple endocrine neoplasia type 2A.
    Human mutation, 1998, Volume: Suppl 1

    Topics: Amino Acid Sequence; Base Sequence; Cysteine; DNA; DNA Mutational Analysis; Drosophila Proteins; Exons; Gene Duplication; Humans; Male; Middle Aged; Multiple Endocrine Neoplasia Type 2a; Polymorphism, Single-Stranded Conformational; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Receptor Protein-Tyrosine Kinases

1998
Molecular analysis of the ret and GDNF genes in a family with multiple endocrine neoplasia type 2A and Hirschsprung disease.
    The Journal of clinical endocrinology and metabolism, 1998, Volume: 83, Issue:9

    Topics: Aged; Child, Preschool; Cysteine; DNA; Drosophila Proteins; Female; Glial Cell Line-Derived Neurotrophic Factor; Glial Cell Line-Derived Neurotrophic Factor Receptors; Hirschsprung Disease; Humans; Male; Middle Aged; Multiple Endocrine Neoplasia Type 2a; Nerve Growth Factors; Nerve Tissue Proteins; Pedigree; Point Mutation; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Receptor Protein-Tyrosine Kinases

1998
Dual effect on the RET receptor of MEN 2 mutations affecting specific extracytoplasmic cysteines.
    Oncogene, 1998, Dec-03, Volume: 17, Issue:22

    Topics: 3T3 Cells; Amino Acid Substitution; Animals; Cell Transformation, Neoplastic; Cysteine; Dimerization; Disulfides; Drosophila Proteins; Glycosylation; Hirschsprung Disease; Humans; Membrane Proteins; Mice; Models, Biological; Multiple Endocrine Neoplasia Type 2a; PC12 Cells; Phosphotyrosine; Precipitin Tests; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Rats; Receptor Protein-Tyrosine Kinases; Transcriptional Activation

1998
Germline RET 634 mutation positive MEN 2A-related C-cell hyperplasias have genetic features consistent with intraepithelial neoplasia.
    The Journal of clinical endocrinology and metabolism, 2001, Volume: 86, Issue:8

    Topics: Amino Acid Substitution; Antigens, Nuclear; Autoantigens; Calcitonin; Carcinoma, Medullary; Cysteine; DNA Primers; Drosophila Proteins; Female; Focal Epithelial Hyperplasia; Genes, Retinoblastoma; Germ-Line Mutation; Humans; Ki-67 Antigen; Loss of Heterozygosity; Multiple Endocrine Neoplasia Type 2a; Nerve Tissue Proteins; Neurofibromin 1; Nuclear Proteins; Polymorphism, Single Nucleotide; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Receptor Protein-Tyrosine Kinases; Thyroid Diseases; Thyroid Neoplasms; Thyroidectomy; Tyrosine

2001
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