cysteine and Chagas Disease

cysteine has been researched along with Chagas Disease in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's1 (12.50)29.6817
2010's5 (62.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Freitag-Pohl, S; Murillo, AM; Pohl, E; Silber, AM; Sowerby, K1
Bottazzi, ME; Brown, EL; Essigmann, HT; Gunter, SM; Hotez, PJ; Jones, KM; Seid, CA; Strych, U; Zhan, B1
Garg, NJ; Wiktorowicz, JE; Zago, MP1
Batthyány, C; Buschiazzo, A; Demicheli, V; Durán, R; Hugo, M; Larrieux, N; Lima, A; Martí, MA; Martinez, A; Moreno, DM; Peluffo, G; Petruk, AA; Piacenza, L; Piñeyro, D; Radi, R; Robello, C; Trujillo, M1
Bottazzi, ME; Gutierrez, A; Hammond, M; Hotez, PJ; Hudspeth, E; Jones, KM; Keegan, B; Liu, Z; McAtee, CP; Pollet, J; Respress, JL; Seid, CA; Strych, U; Versteeg, L; Wei, J; Zhan, B1
Nicoll-Griffith, DA1
Becker, I; Berzunza, M; Cabrera, N; de Gómez-Puyou, MT; García, J; Gómez-Puyou, A; López-Calahorra, F; Olivares-Illana, V; Pérez-Montfort, R; Rodríguez-Romero, A1
Chabé, F; Gomez-Corvera, R; Guevara-Espinoza, A; Ouaissi, A; Taibi, A1

Reviews

1 review(s) available for cysteine and Chagas Disease

ArticleYear
Use of cysteine-reactive small molecules in drug discovery for trypanosomal disease.
    Expert opinion on drug discovery, 2012, Volume: 7, Issue:4

    Topics: Animals; Biphenyl Compounds; Catalytic Domain; Cathepsin K; Chagas Disease; Cysteine; Cysteine Endopeptidases; Cysteine Proteases; Cysteine Proteinase Inhibitors; Dipeptides; Dogs; Drug Discovery; Humans; Leishmaniasis; Mice; Phenylalanine; Piperazines; Prodrugs; Protein Binding; Protozoan Proteins; Tosyl Compounds; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African; Vinyl Compounds

2012

Other Studies

7 other study(ies) available for cysteine and Chagas Disease

ArticleYear
Cysteine synthase: multiple structures of a key enzyme in cysteine synthesis and a potential drug target for Chagas disease and leishmaniasis.
    Acta crystallographica. Section D, Structural biology, 2023, Jun-01, Volume: 79, Issue:Pt 6

    Topics: Animals; Cattle; Chagas Disease; Cysteine; Cysteine Synthase; Leishmaniasis; Trypanosoma cruzi

2023
Mutations to Cysteine Residues in the Trypanosoma cruzi B-Cell Superantigen Tc24 Diminish Susceptibility to IgM-Mediated Hydrolysis.
    The Journal of parasitology, 2017, Volume: 103, Issue:5

    Topics: Animals; Antibodies, Protozoan; B-Lymphocytes; Calcium-Binding Proteins; Chagas Disease; Cysteine; Hydrolysis; Immunity, Innate; Immunization; Immunoglobulin M; Mice; Mutation; Protein Isoforms; Protozoan Vaccines; Sequence Alignment; Serine; Superantigens; Trypanosoma cruzi

2017
Fluorescence Proteomic Technology to Analyze Peripheral Blood Mononuclear Cells in Chronic Chagas Disease.
    Methods in molecular biology (Clifton, N.J.), 2019, Volume: 1955

    Topics: Biomarkers; Chagas Disease; Chronic Disease; Cysteine; Electrophoresis, Gel, Two-Dimensional; Fluorescence; Humans; Leukocytes, Mononuclear; Mass Spectrometry; Nitric Oxide; Proteins; Proteomics

2019
Structural and molecular basis of the peroxynitrite-mediated nitration and inactivation of Trypanosoma cruzi iron-superoxide dismutases (Fe-SODs) A and B: disparate susceptibilities due to the repair of Tyr35 radical by Cys83 in Fe-SODB through intramolec
    The Journal of biological chemistry, 2014, May-02, Volume: 289, Issue:18

    Topics: Animals; Binding Sites; Blotting, Western; Catalytic Domain; Chagas Disease; Crystallography, X-Ray; Cysteine; Electron Spin Resonance Spectroscopy; Electron Transport; Enzyme Activation; Host-Parasite Interactions; Isoenzymes; Kinetics; Models, Molecular; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Nitrates; Peroxynitrous Acid; Protein Binding; Protein Structure, Secondary; Protozoan Proteins; Reactive Oxygen Species; Superoxide Dismutase; Trypanosoma cruzi; Tyrosine

2014
Cysteine mutagenesis improves the production without abrogating antigenicity of a recombinant protein vaccine candidate for human chagas disease.
    Human vaccines & immunotherapeutics, 2017, 03-04, Volume: 13, Issue:3

    Topics: Adjuvants, Immunologic; Animals; Antibodies, Protozoan; Chagas Disease; Cysteine; Disease Models, Animal; Female; Heart; Interferon-gamma; Leukocytes, Mononuclear; Mice, Inbred BALB C; Mutagenesis; Parasite Load; Protozoan Proteins; Protozoan Vaccines; Recombinant Proteins; Survival Analysis; Trypanosoma cruzi; Vaccines, Synthetic

2017
Perturbation of the dimer interface of triosephosphate isomerase and its effect on Trypanosoma cruzi.
    PLoS neglected tropical diseases, 2007, Oct-31, Volume: 1, Issue:1

    Topics: Aniline Compounds; Animals; Chagas Disease; Cysteine; Dimerization; Escherichia coli; Humans; Incidence; Kinetics; Models, Molecular; Protein Conformation; Recombinant Proteins; Sequence Deletion; Triose-Phosphate Isomerase; Trypanosoma cruzi; X-Ray Diffraction

2007
A novel and basic mechanism of immunosuppression in Chagas' disease: Trypanosoma cruzi releases in vitro and in vivo a protein which induces T cell unresponsiveness through specific interaction with cysteine and glutathione.
    Immunology letters, 1995, Volume: 48, Issue:3

    Topics: Animals; Cells, Cultured; Chagas Disease; Cysteine; Glutathione; Humans; Immune Tolerance; Mice; Mice, Inbred BALB C; Protozoan Proteins; Spleen; T-Lymphocytes; Thymidine; Trypanosoma cruzi

1995