cysteine and Cataract

cysteine has been researched along with Cataract in 65 studies

Research

Studies (65)

TimeframeStudies, this research(%)All Research%
pre-199026 (40.00)18.7374
1990's14 (21.54)18.2507
2000's13 (20.00)29.6817
2010's11 (16.92)24.3611
2020's1 (1.54)2.80

Authors

AuthorsStudies
Hou, W; Pande, A; Pande, J1
Schey, KL; Wang, Z1
Fan, X; Monnier, VM; Ramkumar, S; Wang, B; Yang, S1
Hogg, PJ; Quinlan, RA1
Alcaíno, CA; Altenberg, GA; Arévalo, NJ; Arjona, RJ; Canan, JG; González, W; Moraga-Amaro, R; Orellana, VP; Retamal, MA; Reuss, L; Rojas, CG; Stehberg, J1
Donaldson, PJ; Lam, L; Li, B; Lim, JC1
King, J; Schafheimer, N; Schey, K; Wang, Z1
Fan, X; Guo, M; Hom, G; Li, B; Monnier, VM; Vaysburg, D; Wang, B; Yang, J; Zhou, S1
Adkar, BV; King, JA; Serebryany, E; Shabab, M; Shakhnovich, EI; Woodard, JC1
Fan, X; Guo, M; Hom, G; Li, B; Monnier, VM; Wang, B; Yang, J; Zhou, S1
Hains, PG; Truscott, RJ1
Claxton, DP; Koteiche, HA; Kumar, MS; Mchaourab, HS1
Altenberg, GA; Retamal, MA; Reuss, L; Yin, S1
Gillot, D; Pande, A; Pande, J1
Andley, UP; Reilly, MA1
David, LL; Giblin, FJ; Leverenz, VR; Simpanya, MF; Wilmarth, PA1
SMIRNOV, SN1
CHERIKCHI, LE1
LAJTHA, LG; PIRIE, A1
Craghill, J; Cronshaw, AD; Harding, JJ1
DISCHE, Z; ZIL, H1
VON SALLMANN, L1
Aquilina, JA; Hains, PG; Korlimbinis, A; Truscott, RJ1
Gu, F; Huang, S; Li, C; Li, D; Ma, X; Zhai, H; Zhao, L1
Gao, C; Huang, S; Li, F; Liu, S; Ma, X; Wang, S; Zhang, M; Zhao, B; Zhu, S1
Mal'tsev, EV1
Gandolfi, AJ; Jaffe, DR; Nagle, RB1
Ingalls, LK; Kern, HL; Weiner, BC; Zolot, S1
Hirota, K; Ikeda, M; Ohmori, S; Tsuboi, S; Uda, N1
Blundell, T; Driessen, H; Lindley, P; Mahadevan, D; Miller, L; Moss, D; Narebor, M; Slingsby, C; Summers, L; White, H1
Khuteta, KP; Kulshrestha, OP; Kulshrestha, SN; Shukla, Y1
Garner, MH; Spector, A2
Qin, W; Smith, DL; Smith, JB1
Dickerson, JE; Lou, MF1
Cui, XL; Lou, MF; Xu, GT1
Cohen, JF; Holleschau, AM; Nagasawa, HT; Rathbun, WB1
Holleschau, AM; Killen, CE; Nagasawa, HT; Rathbun, WB1
Takemoto, LJ2
Holleschau, AM; Nagasawa, HT; Rathbun, WB1
Altomare, E; Cardia, L; Grattagliano, I; Micelli-Ferrari, T; Signorile, A; Vendemaile, G1
Aleo, MD; Walsh Clang, CM1
Bantseev, V; Bhardwaj, R; Nagasawa, H; Rathbun, W; Trevithick, JR1
Richer, SP; Rose, RC1
Asherie, N; Benedek, GB; King, JA; Lomakin, A; Lubsen, NH; Ogun, O; Pande, A; Pande, J; Walton, D1
Agardh, C; Agardh, E; Hultberg, B1
Chévez-Barrios, P; Lieberman, MW; Ou, CN; Rojas, E; Wiseman, AL1
Cobb, BA; Petrash, JM1
Asherie, N; Benedek, GB; King, J; Lomakin, A; Lomakin, J; Ogun, O; Pande, A; Pande, J; Stern, LJ; Zarutskie, JA1
Augusteyn, RC; Truscott, RJ1
Fowler, B; Law, EA1
Azari, P; Takemoto, LJ1
Bando, M; Obazawa, H; Sueno, T1
Dickerson, JE; Garadi, R; Lou, MF1
Clark, JI; Giblin, FJ; Ikebe, H; Livesey, JC; Reddy, VN1
Augusteyn, RC; Hum, TP1
Oeriu, S; Vancea, P1
Pirie, A1
Bertelsen, TI; Ehlers, N1
Iakovlev, VG; Krotova, SI; Sharpan', AS; Shipitsyna, GK; Tikhonova, MA; Zotova, MG1
Perlis, IuV1
Bocci, N; Calabrò, S; Fiore, C; Testa, M1
Khodak, RA1
Bokhon, NN1

Reviews

2 review(s) available for cysteine and Cataract

ArticleYear
[Conservative treatment of cataract].
    Oftalmologicheskii zhurnal, 1984, Issue:7

    Topics: Acridines; Aged; Aging; Cataract; Crystallins; Cysteine; Drug Therapy, Combination; Humans; Hypercholesterolemia; Hyperglycemia; Iontophoresis; Lens, Crystalline; Methylthiouracil; Middle Aged; Ophthalmic Solutions; Procaine; Protein Denaturation; Tiopronin; Vitamins

1984
Effect of radioprotective agents on X-ray cataracts.
    Lens and eye toxicity research, 1989, Volume: 6, Issue:4

    Topics: Amifostine; Animals; Cataract; Cysteine; Galactose; Lens, Crystalline; Radiation Injuries, Experimental; Radiation-Protective Agents

1989

Other Studies

63 other study(ies) available for cysteine and Cataract

ArticleYear
Oxidation of active cysteines mediates protein aggregation of S10R, the cataract-associated mutant of mouse GammaB-crystallin.
    Proteins, 2022, Volume: 90, Issue:11

    Topics: Animals; Cataract; Connexins; Cysteine; Disulfides; gamma-Crystallins; Glutathione; Humans; Lens, Crystalline; Mice; Mutant Proteins; Oxidation-Reduction; Protein Aggregates

2022
Quantification of thioether-linked glutathione modifications in human lens proteins.
    Experimental eye research, 2018, Volume: 175

    Topics: Adolescent; Alanine; Aminobutyrates; Cataract; Cellular Senescence; Chromatography, Liquid; Crystallins; Cysteine; Glutathione; Humans; Lens, Crystalline; Middle Aged; Protein Processing, Post-Translational; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfides; Threonine; Tissue Donors; Young Adult

2018
Reactive cysteine residues in the oxidative dimerization and Cu
    Biochimica et biophysica acta. Molecular basis of disease, 2018, Volume: 1864, Issue:11

    Topics: Adolescent; Age Factors; Aged; Cataract; Cations, Divalent; Child; Child, Preschool; Copper; Cysteine; Disulfides; gamma-Crystallins; Glutathione; Humans; Lens, Crystalline; Molecular Docking Simulation; Mutagenesis, Site-Directed; Mutation; Oxidative Stress; Protein Aggregation, Pathological; Protein Multimerization; Recombinant Proteins

2018
γ-Crystallin redox-detox in the lens.
    The Journal of biological chemistry, 2018, 11-16, Volume: 293, Issue:46

    Topics: Amino Acid Substitution; Cataract; Cysteine; Disulfides; gamma-Crystallins; Humans; Lens, Crystalline; Mutation; Oxidation-Reduction; Oxidoreductases Acting on Sulfur Group Donors

2018
Cx46 hemichannel modulation by nitric oxide: Role of the fourth transmembrane helix cysteine and its possible involvement in cataract formation.
    Nitric oxide : biology and chemistry, 2019, 05-01, Volume: 86

    Topics: Amino Acid Sequence; Animals; Cataract; Cell Line; Connexins; Cricetulus; Cysteine; Gap Junctions; Humans; Male; Membrane Potentials; Mesocricetus; Mice; Nitric Oxide; Nitrosation; Protein Conformation, alpha-Helical; Protein Processing, Post-Translational; Rats, Sprague-Dawley; Sequence Alignment; Xenopus laevis; Zebrafish

2019
Molecular identification and cellular localization of a potential transport system involved in cystine/cysteine uptake in human lenses.
    Experimental eye research, 2013, Volume: 116

    Topics: Adult; Aged; Amino Acid Transport System X-AG; Biological Transport; Blotting, Western; Cataract; Cysteine; Cystine; Humans; Immunohistochemistry; Lens, Crystalline; Middle Aged; Reverse Transcriptase Polymerase Chain Reaction; RNA

2013
Tyrosine/cysteine cluster sensitizing human γD-crystallin to ultraviolet radiation-induced photoaggregation in vitro.
    Biochemistry, 2014, Feb-18, Volume: 53, Issue:6

    Topics: Amino Acid Substitution; Cataract; Cysteine; gamma-Crystallins; Humans; Lens, Crystalline; Protein Denaturation; Protein Folding; Protein Structure, Quaternary; Tryptophan; Tyrosine; Ultraviolet Rays

2014
Evidence of Highly Conserved β-Crystallin Disulfidome that Can be Mimicked by In Vitro Oxidation in Age-related Human Cataract and Glutathione Depleted Mouse Lens.
    Molecular & cellular proteomics : MCP, 2015, Volume: 14, Issue:12

    Topics: Aging; Animals; beta-Crystallins; Cataract; Cell Line; Cysteine; Disease Models, Animal; Disulfides; Glutathione; Humans; In Vitro Techniques; Lens, Crystalline; Mice; Oxidation-Reduction; Protein Conformation; Proteomics

2015
An Internal Disulfide Locks a Misfolded Aggregation-prone Intermediate in Cataract-linked Mutants of Human γD-Crystallin.
    The Journal of biological chemistry, 2016, 09-02, Volume: 291, Issue:36

    Topics: Amino Acid Substitution; Cataract; Cysteine; Disulfides; gamma-Crystallins; Humans; Mutation, Missense; Protein Aggregates; Protein Domains; Protein Folding; Protein Structure, Secondary

2016
The oxidized thiol proteome in aging and cataractous mouse and human lens revealed by ICAT labeling.
    Aging cell, 2017, Volume: 16, Issue:2

    Topics: Adolescent; Aged; Aging; Amino Acid Sequence; Animals; Antioxidants; Cataract; Child; Child, Preschool; Cross-Linking Reagents; Cysteine; Glutathione; Humans; Intermediate Filaments; Isotope Labeling; Lens, Crystalline; Mice, Knockout; Oxidation-Reduction; Peptides; Protein Deglycase DJ-1; Proteome; Sulfhydryl Compounds

2017
Proteomic analysis of the oxidation of cysteine residues in human age-related nuclear cataract lenses.
    Biochimica et biophysica acta, 2008, Volume: 1784, Issue:12

    Topics: Aging; Cataract; Crystallins; Cysteine; Disulfides; Humans; Lens Nucleus, Crystalline; Oxidation-Reduction; Proteomics

2008
Disulfide cross-links in the interaction of a cataract-linked alphaA-crystallin mutant with betaB1-crystallin.
    FEBS letters, 2009, Jan-05, Volume: 583, Issue:1

    Topics: alpha-Crystallin A Chain; Amino Acid Substitution; beta-Crystallin B Chain; Cataract; Cross-Linking Reagents; Cysteine; Disulfides; Humans; Mutation

2009
Modulation of Cx46 hemichannels by nitric oxide.
    American journal of physiology. Cell physiology, 2009, Volume: 296, Issue:6

    Topics: Animals; Cataract; Connexin 43; Connexins; Cysteine; Dithiothreitol; Fluorescent Dyes; Gap Junctions; Ion Channel Gating; Kinetics; Membrane Potentials; Mutation; Nitric Oxide; Nitric Oxide Donors; Oocytes; Oxidation-Reduction; Permeability; Rats; Recombinant Fusion Proteins; Reducing Agents; S-Nitrosoglutathione; Xenopus laevis

2009
The cataract-associated R14C mutant of human gamma D-crystallin shows a variety of intermolecular disulfide cross-links: a Raman spectroscopic study.
    Biochemistry, 2009, Jun-09, Volume: 48, Issue:22

    Topics: Amino Acid Substitution; Arginine; Cataract; Cross-Linking Reagents; Crystallins; Cysteine; Disulfides; gamma-Crystallins; Humans; Oxidation-Reduction; Protein Conformation; Protein Structure, Secondary; Recombinant Proteins; Spectrum Analysis, Raman; Sulfhydryl Compounds

2009
Quantitative biometric phenotype analysis in mouse lenses.
    Molecular vision, 2010, Jun-08, Volume: 16

    Topics: Aging; alpha-Crystallin A Chain; Animals; Arginine; Biometry; Cataract; Cysteine; Eye Abnormalities; Genotype; Heterozygote; Homozygote; Image Processing, Computer-Assisted; Lens, Crystalline; Mice; Mice, Knockout; Mice, Transgenic; Mutation; Organ Size; Phenotype; Solubility

2010
Shotgun proteomic analysis of S-thiolation sites of guinea pig lens nuclear crystallins following oxidative stress in vivo.
    Molecular vision, 2013, Volume: 19

    Topics: Animals; Binding Sites; Cataract; Crystallins; Cysteine; Disease Models, Animal; Glutathione; Guinea Pigs; Hyperoxia; Lens Nucleus, Crystalline; Oxidative Stress; Protein Processing, Post-Translational; Proteomics; Solubility; Sulfhydryl Compounds; Tandem Mass Spectrometry

2013
[A modified conservative treatment of incipient cataract].
    Oftalmologicheskii zhurnal, 1962, Volume: 17

    Topics: Cataract; Cysteine; Humans

1962
[CLINICO-EXPERIMENTAL STUDY OF CYSTEINE THERAPY IN CATARACT].
    Oftalmologicheskii zhurnal, 1964, Volume: 19

    Topics: Cataract; Cysteine; Drug Therapy; Humans; Lens, Crystalline

1964
Possible mechanism of cysteine protection against radiation cataract.
    Nature, 1959, Oct-10, Volume: 184

    Topics: Abnormalities, Radiation-Induced; Cataract; Cysteine; Radiation Protection

1959
The identification of a reaction site of glutathione mixed-disulphide formation on gammaS-crystallin in human lens.
    The Biochemical journal, 2004, May-01, Volume: 379, Issue:Pt 3

    Topics: Aging; Amino Acid Sequence; Blotting, Western; Cataract; Cysteine; Dimerization; Disulfides; Electrophoresis, Polyacrylamide Gel; gamma-Crystallins; Glutathione; Humans; Lens, Crystalline; Molecular Sequence Data; Molecular Weight

2004
Studies on the oxidation of cysteine to cystine in lens proteins during cataract formation.
    American journal of ophthalmology, 1951, Volume: 34, Issue:5 2

    Topics: Cataract; Crystallins; Cysteine; Cystine; Lens, Crystalline

1951
Further efforts to influence x-ray cataract by chemical agents.
    A.M.A. archives of ophthalmology, 1952, Volume: 47, Issue:1

    Topics: Cataract; Cysteine; Radiation Effects; X-Rays

1952
3-Hydroxykynurenine oxidizes alpha-crystallin: potential role in cataractogenesis.
    Biochemistry, 2006, Feb-14, Volume: 45, Issue:6

    Topics: alpha-Crystallins; Animals; Catalysis; Cataract; Cattle; Chromatography, High Pressure Liquid; Cysteine; Humans; Kynurenine; Lens, Crystalline; Mass Spectrometry; Methionine; Oxidation-Reduction; Oxidative Stress; Sunscreening Agents; Tryptophan; Ultraviolet Rays

2006
A novel mutation in major intrinsic protein of the lens gene (MIP) underlies autosomal dominant cataract in a Chinese family.
    Molecular vision, 2007, Sep-11, Volume: 13

    Topics: Adult; Amino Acid Substitution; Aquaporins; Arginine; Asian People; Cataract; Cysteine; Cytosine; DNA Mutational Analysis; Eye Proteins; Female; Genes, Dominant; Genetic Linkage; Haplotypes; Humans; Lod Score; Male; Membrane Glycoproteins; Mutation; Pedigree; Thymine

2007
Mutation G61C in the CRYGD gene causing autosomal dominant congenital coralliform cataracts.
    Molecular vision, 2008, Mar-04, Volume: 14

    Topics: Adult; Amino Acid Sequence; Base Sequence; Cataract; Chromatography, High Pressure Liquid; Chromosomes, Human; Crystallins; Cysteine; DNA Mutational Analysis; Female; gamma-Crystallins; Genes, Dominant; Genetic Markers; Glycine; Haplotypes; Humans; Lens, Crystalline; Lod Score; Male; Molecular Sequence Data; Mutation; Nucleic Acid Denaturation; Pedigree; Protein Isoforms; Sequence Alignment

2008
Chronic toxicity of S-(trans-1,2-dichlorovinyl)-L-cysteine in mice.
    Journal of applied toxicology : JAT, 1984, Volume: 4, Issue:6

    Topics: Animals; Cataract; Cysteine; Glutathione; Kidney; Kidney Tubules; Male; Mice

1984
Patterns in effects of sulfhydryl reagents on transport in bovine lens.
    Current eye research, 1984, Volume: 3, Issue:12

    Topics: Animals; Biological Transport; Calcium; Cataract; Cattle; Cell Membrane Permeability; Cysteine; Energy Metabolism; Glutathione; Lens, Crystalline; Membrane Proteins; Rubidium; Sodium; Sulfhydryl Compounds

1984
S-(1,2-dicarboxyethyl)glutathione and S-(1,2-dicarboxyethyl)L-cysteine in lens.
    Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie, 1984, Volume: 22, Issue:4

    Topics: Animals; Cataract; Cattle; Chromatography, High Pressure Liquid; Cysteine; Dinitrofluorobenzene; Dogs; Galactose; Glutathione; Guinea Pigs; Lens, Crystalline; Rabbits; Rats; Species Specificity; Tuna

1984
The molecular structures and interactions of bovine and human gamma-crystallins.
    Ciba Foundation symposium, 1984, Volume: 106

    Topics: Amino Acid Sequence; Animals; Cataract; Cattle; Crystallins; Cysteine; Humans; Models, Molecular; Molecular Conformation; Oxidation-Reduction; Rats; Sulfhydryl Compounds

1984
Study of cysteine, cystine and methionine in normal and cataractous human lenses.
    Indian journal of ophthalmology, 1983, Volume: 31, Issue:3

    Topics: Amino Acids, Sulfur; Cataract; Cysteine; Cystine; Humans; Lens, Crystalline; Methionine

1983
Selective oxidation of cysteine and methionine in normal and senile cataractous lenses.
    Proceedings of the National Academy of Sciences of the United States of America, 1980, Volume: 77, Issue:3

    Topics: Aged; Aging; Cataract; Crystallins; Cysteine; Humans; Lens, Crystalline; Membrane Proteins; Methionine; Middle Aged; Oxidation-Reduction

1980
Sulfur oxidation in selected human cortical cataracts and nuclear cataracts.
    Experimental eye research, 1980, Volume: 31, Issue:3

    Topics: Cataract; Crystallins; Cysteine; Disulfides; Humans; Lens, Crystalline; Membrane Proteins; Membranes; Methionine; Oxidation-Reduction

1980
Reaction of aspirin with cysteinyl residues of lens gamma-crystallins: a mechanism for the proposed anti-cataract effect of aspirin.
    Biochimica et biophysica acta, 1993, Apr-30, Volume: 1181, Issue:2

    Topics: Acetylation; Amino Acid Sequence; Animals; Aspirin; Cataract; Cattle; Crystallins; Cyanates; Cysteine; Lens, Crystalline; Molecular Sequence Data; Pepsin A; Peptide Fragments

1993
A new mixed disulfide species in human cataractous and aged lenses.
    Biochimica et biophysica acta, 1993, Jun-11, Volume: 1157, Issue:2

    Topics: Adult; Aged; Aging; Cataract; Crystallins; Cysteine; Dipeptides; Disulfides; Formates; Glutathione; Humans; Lens, Crystalline; Middle Aged

1993
Further studies on the dynamic changes of glutathione and protein-thiol mixed disulfides in H2O2 induced cataract in rat lenses: distributions and effect of aging.
    Current eye research, 1995, Volume: 14, Issue:10

    Topics: Aging; Animals; Cataract; Crystallins; Culture Media; Cysteine; Disease Models, Animal; Disulfides; Glutathione; Hydrogen Peroxide; Lens Cortex, Crystalline; Lens Nucleus, Crystalline; Lens, Crystalline; Organ Culture Techniques; Oxidants; Oxidative Stress; Rats; Rats, Sprague-Dawley

1995
Prevention of acetaminophen- and naphthalene-induced cataract and glutathione loss by CySSME.
    Investigative ophthalmology & visual science, 1996, Volume: 37, Issue:5

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Cataract; Chromatography, High Pressure Liquid; Cysteine; Drug Combinations; Glutathione; Lens, Crystalline; Liver; Male; Mercaptoethanol; Mice; Mice, Inbred C57BL; Naphthalenes; Organ Culture Techniques; Prodrugs; Rats; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms

1996
Maintenance of hepatic glutathione homeostasis and prevention of acetaminophen-induced cataract in mice by L-cysteine prodrugs.
    Biochemical pharmacology, 1996, May-03, Volume: 51, Issue:9

    Topics: Acetaminophen; Animals; Cataract; Cysteine; Glutathione; Homeostasis; Liver; Male; Mice; Mice, Inbred C57BL; Prodrugs

1996
Oxidation of cysteine residues from alpha-A crystallin during cataractogenesis of the human lens.
    Biochemical and biophysical research communications, 1996, Jun-14, Volume: 223, Issue:2

    Topics: Anaerobiosis; Cataract; Chaperonins; Crystallins; Cysteine; Humans; Mass Spectrometry; Oxidation-Reduction; Peptide Fragments; Reference Values

1996
An HPLC radiotracer method for assessing the ability of L-cysteine prodrugs to maintain glutathione levels in the cultured rat lens.
    Current eye research, 1996, Volume: 15, Issue:5

    Topics: Animals; Carbon Radioisotopes; Cataract; Chromatography, High Pressure Liquid; Cysteine; Dipeptides; Glutathione; Glycine; Lens, Crystalline; Male; Prodrugs; Rats; Rats, Sprague-Dawley; Spectrophotometry, Ultraviolet

1996
Oxidative protein damage in human diabetic eye: evidence of a retinal participation.
    European journal of clinical investigation, 1997, Volume: 27, Issue:2

    Topics: Aged; Antioxidants; Ascorbic Acid; Cataract; Cysteine; Diabetic Retinopathy; Eye; Female; Free Radical Scavengers; Glutathione Peroxidase; Humans; Lens, Crystalline; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Retina; Sulfhydryl Compounds; Vitreous Body

1997
Disulfide bond formation of cysteine-37 and cysteine-66 of beta B2 crystallin during cataractogenesis of the human lens.
    Experimental eye research, 1997, Volume: 64, Issue:4

    Topics: Aged; Cataract; Chromatography; Crystallins; Cysteine; Humans; Mass Spectrometry; Middle Aged

1997
Mechanistic analysis of S-(1,2-dichlorovinyl)-L-cysteine-induced cataractogenesis in vitro.
    Toxicology and applied pharmacology, 1997, Volume: 146, Issue:1

    Topics: Adenosine Triphosphate; Animals; Cataract; Cysteine; Glutathione; Male; Methimazole; Rats; Rats, Sprague-Dawley

1997
Antioxidants and cataract: (cataract induction in space environment and application to terrestrial aging cataract).
    Biochemistry and molecular biology international, 1997, Volume: 42, Issue:6

    Topics: Animals; Antioxidants; Ascorbic Acid; Carbolines; Cataract; Cysteine; Dose-Response Relationship, Radiation; In Vitro Techniques; L-Lactate Dehydrogenase; Lens, Crystalline; Occupational Diseases; Radiation-Protective Agents; Rats; Ribose; Taurine; Thioctic Acid; Vitamin E

1997
Water soluble antioxidants in mammalian aqueous humor: interaction with UV B and hydrogen peroxide.
    Vision research, 1998, Volume: 38, Issue:19

    Topics: Aged; Analysis of Variance; Animals; Antioxidants; Aqueous Humor; Ascorbic Acid; Cataract; Chromatography, High Pressure Liquid; Cysteine; Disease Models, Animal; Female; Glutathione; Humans; Hydrogen Peroxide; Mammals; Oxidants; Rabbits; Rats; Rats, Sprague-Dawley; Tryptophan; Tyrosine; Ultraviolet Rays; Uric Acid

1998
Molecular basis of a progressive juvenile-onset hereditary cataract.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, Feb-29, Volume: 97, Issue:5

    Topics: Adolescent; Age of Onset; Animals; Arginine; Cataract; Cattle; Crystallins; Cysteine; Humans; Models, Molecular; Protein Structure, Secondary; Protein Structure, Tertiary

2000
Effects of inhibition of glycation and oxidative stress on the development of cataract and retinal vessel abnormalities in diabetic rats.
    Current eye research, 2000, Volume: 21, Issue:1

    Topics: Animals; Blood Glucose; Body Weight; Cataract; Cysteine; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Glutathione; Glycosylation; Guanidines; Male; Oxidative Stress; Probucol; Rats; Rats, Wistar; Retina; Retinal Vessels

2000
Cataract development in gamma-glutamyl transpeptidase-deficient mice.
    Experimental eye research, 2000, Volume: 71, Issue:6

    Topics: Acetylcysteine; Animals; Cataract; Cysteine; Electrophoresis; Free Radical Scavengers; gamma-Glutamyltransferase; Glutathione; Lighting; Mice; Mice, Inbred C57BL

2000
Structural and functional changes in the alpha A-crystallin R116C mutant in hereditary cataracts.
    Biochemistry, 2000, Dec-26, Volume: 39, Issue:51

    Topics: Acetates; Animals; Arginine; Cataract; Cattle; Cell Membrane; Chromatography, Liquid; Chromones; Crystallins; Cysteine; Energy Transfer; Fluorescent Dyes; Humans; Lens, Crystalline; Molecular Chaperones; Mutagenesis, Site-Directed; Mutation, Missense; Peptide Fragments; Protein Binding; Spectrometry, Fluorescence; Structure-Activity Relationship; Temperature

2000
Enhanced crystallization of the Cys18 to Ser mutant of bovine gammaB crystallin.
    Journal of molecular biology, 2001, Dec-07, Volume: 314, Issue:4

    Topics: Amino Acid Substitution; Animals; Cataract; Cattle; Crystallins; Crystallization; Crystallography, X-Ray; Cysteine; gamma-Crystallins; Kinetics; Models, Molecular; Point Mutation; Protein Conformation; Recombinant Proteins; Serine; Solubility; Thermodynamics

2001
Oxidative changes in human lens proteins during senile nuclear cataract formation.
    Biochimica et biophysica acta, 1977, May-27, Volume: 492, Issue:1

    Topics: Adult; Aged; Amino Acids; Cataract; Crystallins; Cysteine; Humans; Methionine; Middle Aged; Oxidation-Reduction; Sulfoxides

1977
Beta-mercaptolactate cysteine disulphiduria in a mentally retarded Scottish male.
    Journal of mental deficiency research, 1976, Volume: 20, Issue:2

    Topics: Abnormalities, Multiple; Adult; Amino Acid Metabolism, Inborn Errors; Cataract; Chromatography, Ion Exchange; Chromatography, Paper; Chromatography, Thin Layer; Chromosome Aberrations; Chromosome Disorders; Consanguinity; Cysteine; Disulfides; Genes, Recessive; Humans; Intellectual Disability; Lactates; Male; Scotland; Sulfhydryl Compounds

1976
Amino acid composition of normal and cataractous human lens proteins.
    Experimental eye research, 1976, Volume: 23, Issue:1

    Topics: Aged; Amino Acids; Cataract; Crystallins; Cysteine; Cystine; Glutathione; Humans; Middle Aged; Tryptophan

1976
Reduced glutathione levels in senile cataractous lens epithelial cells.
    The Tokai journal of experimental and clinical medicine, 1992, Volume: 17, Issue:1

    Topics: Aged; Aged, 80 and over; Aging; Cataract; Cataract Extraction; Chromatography, High Pressure Liquid; Cysteine; Epithelium; Glutathione; Humans; Lens, Crystalline; Middle Aged

1992
The role of protein-thiol mixed disulfides in cataractogenesis.
    Experimental eye research, 1990, Volume: 50, Issue:6

    Topics: Aging; Animals; Cataract; Cysteine; Disulfides; Glutathione; Hydrogen Peroxide; Isoelectric Focusing; Lens, Crystalline; Male; Organ Culture Techniques; Proteins; Rats; Rats, Inbred Strains

1990
The state of sulphydryl groups in proteins isolated from normal and cataractous human lenses.
    Current eye research, 1987, Volume: 6, Issue:9

    Topics: Aged; Aged, 80 and over; Cataract; Chromatography, Gel; Crystallins; Cysteine; Disulfides; Fetus; Humans; Lens, Crystalline; Oxidation-Reduction; Reference Values; Solubility; Sulfhydryl Compounds; Time Factors

1987
[Protective effect of Folcystein in experimental cataract in rabbits (authors transl)].
    Klinische Monatsblatter fur Augenheilkunde, 1973, Volume: 163, Issue:1

    Topics: Age Factors; Animals; Cataract; Cysteine; Disulfides; Folic Acid; Naphthalenes; Oxidation-Reduction; Rabbits; Retina; Time Factors

1973
Reaction of tyrosine oxidation products with proteins of the lens.
    The Biochemical journal, 1968, Volume: 109, Issue:2

    Topics: Animals; Ascorbic Acid; Cataract; Catechol Oxidase; Cattle; Chemical Phenomena; Chemistry; Chromatography, Paper; Crystallins; Cysteine; Dihydroxyphenylalanine; Edetic Acid; Fluorescence; Iron; Naphthoquinones; Oxidation-Reduction; Proteins; Sulfates; Sulfur; Tyrosine

1968
Morphological and histochemical studies on fibrillopathia epitheliocapsularis.
    Acta ophthalmologica, 1969, Volume: 47, Issue:3

    Topics: Aged; Amylases; Arginine; Cataract; Cysteine; Cystine; Endopeptidases; Epithelium; Eye Diseases; Histocytochemistry; Humans; Hyaluronoglucosaminidase; In Vitro Techniques; Lens, Crystalline; Microscopy, Electron; Middle Aged; Ribonucleases; Time Factors; Tryptophan; Tyrosine

1969
[Effect of direct current on cysteine and its penetration through semipermeable membranes].
    Biulleten' eksperimental'noi biologii i meditsiny, 1969, Volume: 68, Issue:11

    Topics: Cataract; Cysteine; Electricity; Electrophoresis; Humans; Membranes; Methods; Permeability

1969
[Active detection and conservative treatment of initial cataract with viceine].
    Oftalmologicheskii zhurnal, 1967, Volume: 22, Issue:2

    Topics: Adult; Aged; Cataract; Cysteine; Humans; Middle Aged

1967
Effect of the oxidation of sulfhydryl groups on lens proteins.
    Experimental eye research, 1968, Volume: 7, Issue:2

    Topics: Albumins; Animals; Cataract; Cattle; Cellulose; Chemical Precipitation; Chromatography, Gel; Chromatography, Ion Exchange; Crystallins; Cysteine; Cystine; Dialysis; Electrophoresis; Hydrogen-Ion Concentration; Lens, Crystalline; Oxidation-Reduction; Proteins; Sulfhydryl Compounds

1968
[Remote results of the treatment of incipient senile cataract by instillation of drops containing cysteine].
    Oftalmologicheskii zhurnal, 1965, Volume: 20, Issue:8

    Topics: Aged; Ascorbic Acid; Cataract; Cysteine; Female; Humans; Male; Middle Aged; Riboflavin

1965
[On the cysteine test of Agarwal as a method of revealing increased sensitivity to crystalline lens protein].
    Oftalmologicheskii zhurnal, 1966, Volume: 21, Issue:2

    Topics: Cataract; Crystallins; Cysteine; Humans; Hypersensitivity; Skin Tests

1966