Compounds > cysteine

cysteine and Carcinoma, Non-Small Cell Lung

cysteine has been researched along with Carcinoma, Non-Small Cell Lung in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.56)18.2507
2000's5 (27.78)29.6817
2010's10 (55.56)24.3611
2020's2 (11.11)2.80

Authors

AuthorsStudies
Biswal, BK; Panda, M1
Chen, J; Chen, X; Du, W; Feng, Y; Li, M; Liu, P; Liu, R; Shi, M; Xu, J; Zhao, L; Zhao, Y1
Backus, KM; Bar-Peled, L; Chang, MW; Cravatt, BF; Dix, MM; Hayward, MM; Horning, BD; Ichu, TA; Ihle, NT; Jiang, P; Kemper, EK; Kok, BP; Olucha, J; Paul, TA; Saez, E; Shaw, RJ; Suciu, RM; Svensson, RU; Vinogradova, EV; Zhu, Z1
Adams, S; Alvarez, SW; Birsoy, K; Moreira, AL; Papagiannakopoulos, T; Possemato, R; Sabatini, DM; Sviderskiy, VO; Terzi, EM1
Gong, Y; Li, C; Li, Z; Lin, X; Liu, X; Luo, Y; Ma, S; Miao, H; Quan, H; Sun, Y; Tang, F; Tian, X; Wang, F; Wang, H; Xiao, Y; Xie, C; Yang, C; You, C; Yu, H; Zhang, J; Zhang, L1
Gao, M; Gao, P; Li, W; Lu, X; Mu, Y; Wang, Q; Wang, Y; Xu, G; Zhao, Y; Zhou, L; Zhou, Y1
Asara, JM; DeNicola, GM; Dibble, CC; Elkins, CM; Falzone, A; Kang, YP; Liu, M; Torrente, L1
Ballard, P; Cantarini, MV; Collier, J; Dickinson, PA; Frewer, P; Martin, S; Pickup, K1
Broggini, M; Brunelli, L; Caiola, E; Lupi, M; Marabese, M; Pastorelli, R1
Cramer, SL; Crighton, T; Labuschagne, C; Lamb, RF; Mason, D; Pardo, OE; Poursaitidis, I; Rowlinson, SW; Roy, R; Seckl, MJ; Stone, E; Triplett, K; Wang, X1
Borghi, M; Castellani, P; Ceccarelli, J; Delfino, L; Ferrini, S; Rubartelli, A; Tosetti, F; Zappia, E1
Chung, FL; Mi, L1
Chiang, EP; Pai, MH; Tang, FY1
Abdelmelek, MF; Blumenschein, GR; Byers, LA; Chen, L; Coombes, KR; Diao, L; Herbst, RS; Heymach, JV; Hong, WK; Ihle, NT; Kim, ES; Larsen, JE; Lee, JJ; Lippman, SM; Liu, S; Minna, JD; Papadimitrakopoulou, V; Powis, G; Saintigny, P; Tang, X; Tsao, A; Wang, J; Wistuba, II; Zhang, S1
Cabrera, W; Dragani, TA; Falvella, FS; Galbiati, F; Galvan, A; Ibanez, O; Mancuso, MT; Manenti, G; Pazzaglia, S; Pignatiello, C; Saran, A; Spinola, M; Zaffaroni, D1
Andjelković, T; Banković, J; Marković, ID; Pesić, M; Rakić, L; Ruzdijić, S1
Baas, F; Beijnen, J; Borst, P; Dekker, H; Lankelma, J; Oude Elferink, RP; Paulusma, C; van Tellingen, O; Zaman, GJ1
Forth, W; Mückter, H; Walther, SC; Walther, UI; Wilhelm, B1

Trials

1 trial(s) available for cysteine and Carcinoma, Non-Small Cell Lung

ArticleYear
Metabolic Disposition of Osimertinib in Rats, Dogs, and Humans: Insights into a Drug Designed to Bind Covalently to a Cysteine Residue of Epidermal Growth Factor Receptor.
    Drug metabolism and disposition: the biological fate of chemicals, 2016, Volume: 44, Issue:8

    Topics: Acrylamides; Adult; Aged; Aniline Compounds; Animals; Antineoplastic Agents; Binding Sites; Biotransformation; Carcinoma, Non-Small-Cell Lung; Cysteine; Cytochrome P-450 CYP3A; Dogs; Drug Administration Schedule; ErbB Receptors; Feces; Female; Hepatocytes; Humans; Lung Neoplasms; Male; Mice; Middle Aged; Piperazines; Protein Binding; Protein Kinase Inhibitors; Rats, Wistar; Serum Albumin, Human; Tissue Distribution

2016

Other Studies

17 other study(ies) available for cysteine and Carcinoma, Non-Small Cell Lung

ArticleYear
Evodiamine inhibits stemness and metastasis by altering the SOX9-β-catenin axis in non-small-cell lung cancer.
    Journal of cellular biochemistry, 2022, Volume: 123, Issue:9

    Topics: Alkaloids; Apoptosis; beta Catenin; Cadherins; Carcinoma, Non-Small-Cell Lung; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cysteine; Humans; Lung Neoplasms; Poly(ADP-ribose) Polymerase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Quinazolines; Reactive Oxygen Species; SOX9 Transcription Factor; Vimentin

2022
COX7A1 enhances the sensitivity of human NSCLC cells to cystine deprivation-induced ferroptosis via regulating mitochondrial metabolism.
    Cell death & disease, 2022, 11-23, Volume: 13, Issue:11

    Topics: Carcinoma, Non-Small-Cell Lung; Cysteine; Cystine; Electron Transport Complex IV; Ferroptosis; Humans; Lung Neoplasms; Mitochondria

2022
Chemical Proteomics Identifies Druggable Vulnerabilities in a Genetically Defined Cancer.
    Cell, 2017, Oct-19, Volume: 171, Issue:3

    Topics: Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cysteine; DAX-1 Orphan Nuclear Receptor; Gene Regulatory Networks; Humans; Kelch-Like ECH-Associated Protein 1; Ligands; Lung Neoplasms; Proteome; Transcriptome

2017
NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis.
    Nature, 2017, 11-30, Volume: 551, Issue:7682

    Topics: Animals; Carbon-Sulfur Lyases; Carcinoma, Non-Small-Cell Lung; Cell Death; Cell Line, Tumor; Cysteine; Glutathione; Humans; Iron-Sulfur Proteins; Lung Neoplasms; Mice; Neoplasm Metastasis; Oxidative Stress; Oxygen; RNA Interference

2017
FePt-Cys nanoparticles induce ROS-dependent cell toxicity, and enhance chemo-radiation sensitivity of NSCLC cells in vivo and in vitro.
    Cancer letters, 2018, 04-01, Volume: 418

    Topics: A549 Cells; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Survival; Chemoradiotherapy; Cisplatin; Cysteine; Humans; Lung Neoplasms; Magnetite Nanoparticles; Platinum; Reactive Oxygen Species; Treatment Outcome

2018
Serum Metabolomics Study of Nonsmoking Female Patients with Non-Small Cell Lung Cancer Using Gas Chromatography-Mass Spectrometry.
    Journal of proteome research, 2019, 05-03, Volume: 18, Issue:5

    Topics: Adult; Aged; Amino Acids; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Case-Control Studies; Cysteine; Diagnosis, Differential; Diglycerides; Early Detection of Cancer; Energy Metabolism; Female; Gas Chromatography-Mass Spectrometry; Humans; Lipid Metabolism; Lung Neoplasms; Metabolome; Middle Aged; Neoplasms; Non-Smokers; Oxidative Stress; Sensitivity and Specificity; Serine

2019
Cysteine dioxygenase 1 is a metabolic liability for non-small cell lung cancer.
    eLife, 2019, 05-20, Volume: 8

    Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cysteine; Cysteine Dioxygenase; DNA Methylation; Gene Silencing; Humans; Kelch-Like ECH-Associated Protein 1; Mice; NF-E2-Related Factor 2; Promoter Regions, Genetic

2019
Different metabolic responses to PI3K inhibition in NSCLC cells harboring wild-type and G12C mutant KRAS.
    Oncotarget, 2016, Aug-09, Volume: 7, Issue:32

    Topics: Amino Acid Substitution; Carcinoma, Non-Small-Cell Lung; Cells, Cultured; Cysteine; Glycine; Humans; Imidazoles; Lung Neoplasms; Mutation, Missense; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Proto-Oncogene Proteins p21(ras); Quinolines; Signal Transduction

2016
Oncogene-Selective Sensitivity to Synchronous Cell Death following Modulation of the Amino Acid Nutrient Cystine.
    Cell reports, 2017, 03-14, Volume: 18, Issue:11

    Topics: Amino Acids; Animals; Breast; Carcinoma, Non-Small-Cell Lung; Cell Death; Cell Line, Tumor; Cell Survival; Cysteine; Cystine; Down-Regulation; Epithelial Cells; ErbB Receptors; Female; Glutathione; Glutathione Peroxidase; Hydrogen Peroxide; Iron; Lung Neoplasms; MAP Kinase Signaling System; Mice, SCID; Mutation; Oncogenes; Phospholipid Hydroperoxide Glutathione Peroxidase

2017
The redox state of the lung cancer microenvironment depends on the levels of thioredoxin expressed by tumor cells and affects tumor progression and response to prooxidants.
    International journal of cancer, 2008, Oct-15, Volume: 123, Issue:8

    Topics: Animals; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Carcinoma, Non-Small-Cell Lung; Cysteine; Disease Progression; Glutathione; HCT116 Cells; Humans; Intramolecular Oxidoreductases; Jurkat Cells; Lung Neoplasms; Macrophage Migration-Inhibitory Factors; Mice; Mice, SCID; Oxidation-Reduction; Oxides; Sulfhydryl Compounds; Thioredoxins

2008
Binding to protein by isothiocyanates: a potential mechanism for apoptosis induction in human non small lung cancer cells.
    Nutrition and cancer, 2008, Volume: 60 Suppl 1

    Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Cysteine; DNA Damage; Humans; Isothiocyanates; Lung Neoplasms; Oxidative Stress; Protein Binding; Protein Carbonylation; Sulfoxides; Thiocyanates; Tubulin

2008
Consumption of S-allylcysteine inhibits the growth of human non-small-cell lung carcinoma in a mouse xenograft model.
    Journal of agricultural and food chemistry, 2010, Oct-27, Volume: 58, Issue:20

    Topics: Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cysteine; Female; Garlic; Growth Inhibitors; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; NF-kappa B; Phosphatidylinositol 3-Kinases; Plant Extracts; Proto-Oncogene Proteins c-akt; Signal Transduction; Xenograft Model Antitumor Assays

2010
Effect of KRAS oncogene substitutions on protein behavior: implications for signaling and clinical outcome.
    Journal of the National Cancer Institute, 2012, Feb-08, Volume: 104, Issue:3

    Topics: Aspartic Acid; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Clinical Trials, Phase II as Topic; Cysteine; Disease-Free Survival; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genes, ras; Genetic Vectors; Glycine; Humans; Immunoblotting; Immunoprecipitation; Kaplan-Meier Estimate; Lentivirus; Lung Neoplasms; Microarray Analysis; Molecular Targeted Therapy; Mutation; Proto-Oncogene Proteins c-akt; Randomized Controlled Trials as Topic; Signal Transduction; TOR Serine-Threonine Kinases; Treatment Outcome; Valine

2012
Met proto-oncogene juxtamembrane rare variations in mouse and humans: differential effects of Arg and Cys alleles on mouse lung tumorigenesis.
    Oncogene, 2005, Feb-03, Volume: 24, Issue:6

    Topics: Adenocarcinoma; Alleles; Amino Acid Sequence; Animals; Arginine; Carcinoma, Non-Small-Cell Lung; Cell Transformation, Neoplastic; Cysteine; Disease Models, Animal; DNA Mutational Analysis; Genetic Linkage; Genetic Predisposition to Disease; Germ-Line Mutation; Humans; Lung Neoplasms; Mice; Mice, Inbred Strains; Molecular Sequence Data; Multifactorial Inheritance; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-met; Receptors, Growth Factor; Receptors, Thrombin; Reverse Transcriptase Polymerase Chain Reaction

2005
Sulfinosine enhances doxorubicin efficacy through synergism and by reversing multidrug resistance in the human non-small cell lung carcinoma cell line (NCI-H460/R).
    Investigational new drugs, 2009, Volume: 27, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Cysteine; DNA Topoisomerases, Type II; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Glutathione; Humans; Lung Neoplasms; Multidrug Resistance-Associated Proteins; Purine Nucleosides

2009
Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Aug-15, Volume: 92, Issue:17

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Arsenites; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Buthionine Sulfoximine; Carcinoma, Non-Small-Cell Lung; Cell Division; Cysteine; Drug Resistance, Multiple; Glutathione; Humans; Kinetics; Lung Neoplasms; Methionine Sulfoximine; Multidrug Resistance-Associated Proteins; Recombinant Proteins; Transfection; Tumor Cells, Cultured

1995
Effect of zinc chloride on GSH synthesis rates in various lung cell lines.
    In vitro & molecular toxicology, 2000,Summer, Volume: 13, Issue:2

    Topics: Carcinoma, Non-Small-Cell Lung; Cell Line; Chlorides; Chromatography, Thin Layer; Cysteine; Epithelial Cells; Fibroblasts; Glutathione; Kinetics; Lung; Lung Neoplasms; Oxidation-Reduction; Protein Biosynthesis; Pulmonary Alveoli; Tumor Cells, Cultured; Zinc Compounds

2000