Compounds > cysteine

cysteine and Breast Neoplasms

cysteine has been researched along with Breast Neoplasms in 137 studies

Research

Studies (137)

TimeframeStudies, this research(%)All Research%
pre-199010 (7.30)18.7374
1990's14 (10.22)18.2507
2000's42 (30.66)29.6817
2010's50 (36.50)24.3611
2020's21 (15.33)2.80

Authors

AuthorsStudies
Chen, G; Lazarus, P; Teslenko, I; Watson, CJW; Xia, Z1
Guo, L; He, Y; Huang, Q; Zhang, X1
Cao, JY; Chen, C; Ge, J; Hu, C; Li, XX; Liu, J; Liu, QS; Liu, QW; Qi, S; Wang, AL; Wang, BL; Wang, JJ; Wang, WC; Wu, H; Zou, FM1
Adams, SL; Brisson, BK; Burgwin, C; Chenoweth, D; Stewart, DC; Volk, SW; Wells, RG1
Abo Qoura, L; Anufrieva, N; Demidkina, T; Koval, V; Kulikova, V; Kushch, A; Lesnova, E; Morozova, E; Pokrovsky, VS; Revtovich, S1
Aa, J; Jiao, Z; Lou, Y; Lu, Z; Peng, Y; Wang, G; Xu, C; Zhang, Y1
Martín Del Valle, EM; Nieto, C; Pérez-Esteban, P; Rodríguez, V; Vega, MA1
Ahmad, J; Al-Khedhairy, AA; Choi, EH; Farshori, NN; Kaushik, N; Kaushik, NK; Khan, F; Nguyen, LN; Saquib, Q; Siddiqui, MA; Wahab, R1
Basilion, JP; Bijlstra, OD; Burggraaf, J; Fallert, LC; Hilling, DE; Kuppen, PJK; Linders, DGJ; March, TL; Pool, M; Straight, B; Vahrmeijer, AL; Valentijn, ARPM; Walker, E1
Hunter, R; Kaschula, CH; Katz, AA; Kusza, DA; Schäfer, G; Smith, M1
Belcher, BP; Bui, H; Friedli, J; Ho, E; Isobe, Y; Machicao, PA; Maimone, TJ; Nomura, DK; So, B; Tong, B1
Chen, M; Fang, L; Zheng, W1
Ji, L; Luo, Y; Sun, Y; Xu, A; Ye, Y; Zhang, W; Zhang, Y1
Chen, K; Gong, J; Liu, F; Peng, Y; Qiao, Y; Si, C; Song, F; Wang, P; Wang, X; Zhou, H1
Koyanagi, S; Kusunose, N; Matsunaga, N; Ohdo, S; Shiromizu, S; Yamauchi, T1
Hong, SE; Jang, SK; Jin, HO; Kim, HA; Kim, MR; Noh, WC; Park, IC; Seong, MK1
Hölzen, L; Parigiani, MA; Reinheckel, T1
Dimasi, N; Gao, C; Kumar, A; Mao, S1
Averkin, DV; Ivanova, AI; Khizhnyak, SD; Mekhtiev, AR; Pakhomov, PM; Perevozova, TV; Vishnevetskii, DV1
Kim, B; Lee, KJ1
Gburek, J; Gołąb, K; Hirnle, L; Janocha, A; Kilar, E; Murawski, M; Siewiński, M; Skiba, T1
Cao, B; Ma, X; Ma, Y; Ma, Z; Shang, K; Wang, J; Wu, S1
Cao, Y; Jiang, Y; Li, W; Li, X; Liu, X; Lv, Y; Mi, J; Wang, Y1
Agatsuma, T1
Baral, R; Basu, A; Bhattacharjee, A; Bhattacharya, S; Biswas, J; Samanta, A1
Kos, J; Mitrović, A; Pečar Fonović, U1
Bateman, LA; Grossman, EA; Huffman, TR; Kleinman, JI; Miyamoto, DK; Nomura, DK; Spradlin, JN; Ward, CC1
Asara, JM; Geck, RC; Ghisolfi, L; Lien, EC; Toker, A1
Jang, JH; Kim, DH; Kim, EH; Kim, ND; Kim, NJ; Kim, SJ; Na, HK; Park, JM; Park, SA; Suh, J; Suh, YG; Surh, YJ1
Baird, CC; Chen, G; Lazarus, P; Luo, S; Truica, CI; Xia, Z1
Bu, W; Duan, J; Kong, Y; Li, L; Li, Z; Liu, F; Liu, H; Ma, B; Sang, Y; Wang, S; Zhang, S1
Cao, Y; Chai, C; Chen, W; Huang, S; Jia, Q; Lu, Y; Ni, W; Pan, Y; Sun, Z; Wang, A; Wang, S; Wang, W; Wei, Z; Wu, Y; Yu, S; Zhang, L; Zheng, Q1
Bagalà, P; Barbarino, R; Cicchetti, S; Di Cristino, D; Di Murro, L; Falco, MD; Janniello, D; Morelli, P; Murgia, A; Ponti, E; Santoni, R; Terenzi, S; Tolu, B; Tortorelli, G1
Kumar, A; Purohit, R; Rajendran, V; Sethumadhavan, R1
Bei, Y; Ding, S; Feng, X; Lu, Y; Shen, P; Sun, T; Zheng, W1
Bogyo, M; Oresic Bender, K; Sanman, LE; Segal, E; Syed, S; van der Linden, WA; Verdoes, M; Withana, NP1
Blanco, MD; Iglesias, I; Martínez, A; Muñiz, E; Teijón, C; Teijón, JM1
Blewett, MM; Cravatt, BF; Wang, C; Weerapana, E1
Ahn, YH; Benjamin, IJ; Boronina, TN; Cole, PA; Cole, RN; Dayalan Naidu, S; Dinkova-Kostova, AT; Pheely, A; Samarasinghe, K; Van Hecke, GC; Zhang, Y1
Garrett, SH; Mehus, AA; Muhonen, WW; Sens, DA; Shabb, JB; Somji, S1
Chan, YC; Chen, CY; Chen, KB; Hung, TC; Lee, WY1
Lin, G; Wang, K; Zhang, H; Zhao, Z1
Brackstone, M; Gupta, V; Kidane, B; Whiston, C; Wright, F; Zabel, PL1
Kong, F; Larson, R; Sims-Mourtada, J; Smith, D; Woodward, WA; Yang, D1
Bhakta, S; Fourie-O'Donohue, A; Gadkar, K; Junutula, JR; Kozak, KR; Lin, K; Liu, L; Mai, E; Raab, H; Ramanujan, S; Sukumaran, S; Xu, K; Yu, SF; Zhang, C1
Blessing, AM; Bollu, LR; Gao, G; Katreddy, RR; Ren, J; Su, F; Wang, J; Weihua, Z; Xu, L1
Calderon-Gierszal, EL; El-Shennawy, L; Frasor, J; Georgieva, G; Kastrati, I; Siklos, MI; Thatcher, GR; Thayer, EN1
Geck, RC; Toker, A1
Gagat, M; Grzanka, A; Grzanka, D; Hałas-Wiśniewska, M; Izdebska, M1
Cao, XJ; Garcia, BA; Kharbanda, A; Runkle, KB; Stypulkowski, E; Wang, W; Witze, ES1
Al Jammaz, I; Okarvi, SM1
Backus, KM; Briggs, KJ; Cao, S; Clardy, J; Cravatt, BF; Gerfen, GJ; Kaelin, WG; Koivunen, P; Olenchock, BA; Patel, H; Richardson, AL; Signoretti, S; Witkiewicz, AK; Zhang, Q1
Andrade, CAS; Frías, IAM; Oliveira, MDL; Pitta, MGR; Rêgo, MJBM; Sacilloti, M; Zanghelini, F1
Alters, SE; Cramer, SL; DiGiovanni, J; Georgiou, G; Huang, P; Keating, MJ; Lamb, C; Liu, J; Rowlinson, S; Saha, A; Stone, E; Tadi, S; Tiziani, S; Triplett, K; Yan, W; Zhang, YJ1
Mahauad-Fernandez, WD; Okeoma, CM1
Gangapurkar, B; Jariwalla, RJ; Nakamura, D1
Baker, MV; Barnard, PJ; Berners-Price, SJ; Filipovska, A; Hickey, JL; Ruhayel, RA1
Belame, A; Burow, ME; Carrier, L; Li, Z; Rowan, BG; Salvo, VA; Thiyagarajah, A1
Zarbl, H; Zhang, X1
Carrico, ZM; Francis, MB; Hsiao, SC; Wu, W1
Buring, JE; Cook, NR; Lee, IM; Lin, J; Manson, JE; Selhub, J; Song, Y; Zhang, SM1
Ali, MS; Chanda, M; Huang, WC; Kohanim, S; Kong, FL; Mendez, R; Oh, C; Tsao, N; Yang, DJ; Zhang, Y1
Jue, DM; Kim, S; Na, HK; Park, SA; Son, PS; Surh, YJ1
Cheung, SH; Evans, EL; Li, L; Shaw, PE1
Agrawal, AK; Ekonjo, GB; Grzebieniak, Z; Marek, G; Milan, M; Siewiński, M; Teterycz, E; Zyoeko, D1
Haffty, BG; Jiang, L; Li, X; Liang, F; Ma, T; Moran, MS; Tao, K; Yan, S; Yang, Q; Yuan, C; Zhang, N1
Kang, KW; Kim, HM; Kim, SK; Kwak, HC; Lee, KH; Lee, KS; Ma, JY; Oh, SJ; Ryu, CS1
Bernier, AJ; Gunasekara, N; Hugh, JC; Lillehoj, E; Shaw, AR; Zhang, J1
Bilotkach, K; Fraser, DA; Molino, NM; Ren, D; Wang, SW1
Amerik, AY; Issaenko, OA1
Czernek, U; Głowacki, R; Jeziorski, A; Kędzierska, M; Olas, B; Piekarski, J; Potemski, P; Szydłowska-Pazera, K1
Kong, FL; Yang, DJ; Young, DP; Yu, DF; Zhang, Y1
Ichibangase, T; Imai, K1
Kang, KW; Kim, SK; Kwak, HC; Lee, JY; Oh, SJ; Phuong, NT; Ryu, CS1
Aranda, E; Cañas, A; De La Haba-Rodríguez, JR; Fuentes, E; Hernández, V; López-Pedrera, C; López-Sánchez, LM; Muñoz-Castañeda, JR; Rodríguez-Ariza, A; Valverde-Estepa, A1
Seidlitz, EP; Singh, G; Ungard, RG1
desBordes, C; Khan, F; Lea, MA; Randolph, VM; Rasheed, M; Shareef, A1
Ang, KK; Azhdarinia, A; Bryant, J; Forster, KM; Hu, M; Kim, EE; Kohanim, S; Oh, CS; Podoloff, DA; Schechter, NR; Wendt, R; Yang, DJ; Yu, DF1
Bohlin, L; Claeson, P; Ek, B; Gullbo, J; Johansson, S; Larsson, R; Lindholm, P; Samuelsson, G; Thunberg, E1
Ahn, SH; Choe, KJ; Choi, JY; Hamajima, N; Han, W; Hirvonen, A; Kang, D; Kim, SU; Lee, KM; Noh, DY; Park, SK; Tajima, K; Yoo, KY; Yoon, KS1
Baldwin, MA; Benz, CC; Meza, JE; Scott, GK1
Colditz, GA; Hankinson, SE; Manson, JE; Selhub, J; Willett, WC; Zhang, SM1
Atmane, N; Dairou, J; Dupret, JM; Rodrigues-Lima, F1
Carlberg, C; Frank, C; Lempiäinen, H; Matilainen, M; Molnár, F1
Li, L; Shaw, PE1
Heikkinen, K; Karppinen, SM; Rapakko, K; Winqvist, R1
Gil-Henn, C; Levitin, F; Prokocimer, Z; Rubinstein, DB; Smorodinsky, NI; Stern, O; Weiss, M; Wreschner, DH; Ziv, R1
Chen, C; Cheng, X; Dong, JT; Dong, XY; Guo, P; Ling, J; Lingrel, JB; Sethi, P; Simons, JW; Sun, X; Zhou, J1
Fujita, T; Kage, K; Sugimoto, Y1
Batista, JF; Perez, MA; Pintado, AP; Quian, YP1
Arias Vásquez, A; Coebergh, JW; González-Zuloeta Ladd, AM; Hofman, A; Stricker, BH; Uitterlinden, AG; van Duijn, CM; Witteman, J1
Callies, R; Frey, UH; Kimmig, R; Otterbach, F; Schmid, KW; Schmitz, KJ; Siffert, W; Wreczycki, C1
Burke, TR; Conrads, TP; Farrar, WL; Kim, HJ; Kim, JY; Liu, F; Meng, Z; Veenstra, TD; Wang, LH1
Abraham, S; Barbas, CF; Guo, F; Lerner, RA; Li, LS; Liu, C; Rader, C; Sinha, SC1
Anderson, DE; Chen, X; Kirk, KL; Shim, JY; Yang, F; Zhang, X1
Filatova, IS; Planas-Silva, MD1
Silva, CM; Weaver, AM1
Crowell, JA; Johnson, WD; Kapetanovic, I; McCormick, DL; Morrissey, RL1
Gapter, LA; Ng, KY; Yuin, OZ1
Chan, S; Evans, H; Fischer, PM; Huber, K; Martin, S; Patel, P; Westwell, AD; Zhang, L1
Jiao, NL; Wang, J; Zheng, J1
Bermisheva, MA; Dörk, T; Gantsev, ShKh; Khusnutdinova, EK; Kochanova, VA; Popov, OS; Zinnamullina, GF1
Beesley, J; Chen, X; Chenevix-Trench, G; Giles, GG; Goldgar, DE; Hopper, JL; Johnatty, SE; Southey, MC; Spurdle, AB1
Leuchtenberger, C; Leuchtenberger, R1
Casey, PJ; Fine, RL; Fu, HW; Sachs, CW; Zhang, L1
Day, RO; deFazio, A; Handel, ML; Sutherland, RL; Watts, CK1
Anker, G; Lien, EA; Lønning, PE; Refsum, H; Ueland, PM1
Casipit, C; Halenbeck, R; Koths, K; Taylor, E; Wang, A1
Day, RO; Handel, ML; Sivertsen, S; Sutherland, RL; Watts, CK1
Beyaert, R; Contreras, R; De Valck, D; Fiers, W; Heyninck, K; Van Criekinge, W1
Chadwick, MP; May, FE; Westley, BR1
Berggren, M; Briehl, MM; Gallegos, A; Gasdaska, JR; Gasdaska, PY; Goodman, D; Paine-Murrieta, GD; Powis, G; Taylor, CW1
Anagnostou, A; Hooker, J; Sigounas, G; Steiner, M1
Ballinger, JR; Duncan, J; Hua, HA; Ichise, M1
Choi, J; Corry, PM; Forman, HJ; Galoforo, SS; Lee, YJ; Ridnour, LA; Sim, JE; Spitz, DR1
Albrechtsen, R; Brakebusch, C; Fässler, R; Fröhlich, C; Gilpin, B; Iba, K; Ishiguro, K; Kojima, T; Langford, JK; Liu, W; Loechel, F; Sanderson, RD; Wewer, UM; Zolkiewska, A1
Croghan, C; Kohlmeier, L; Simonsen, N; Thamm, M; Thorand, B1
Engel, CJ; Girvan, D; Hodgson, N; Holliday, R; Mattar, AG; Zabel, P1
Deryugina, EI; Marchenko, GN; Monosov, EZ; Quigley, JP; Ratnikov, BI; Rozanov, DV; Strongin, AY1
Bishopric, NH; Prentice, H; Webster, KA1
Goodman, JE; Helzlsouer, KJ; Lavigne, JA; Selhub, J; Strickland, PT; Wu, K; Yager, JD1
Ganther, H; Ip, C; Medina, D; Thompson, H1
Chen, HY; Davie, JR; Sun, JM1
Furuta, S; Mason, A; Momand, J; Ortiz, F; Wu, HH; Zhu Sun, X1
Pantopoulos, K; Wang, J1
Agrup, G; Andersson, T; Falck, B; Persson, K; Rorsman, H; Rosengren, AM; Rosengren, E1
Ito, O; Mio, A; Ohshima, T; Sugawara, M; Tsukiyama, I1
Boylan, LM; Spallholz, JE; Yan, L; Yee, JA1
Abe, K; Alper, O; Hitomi, J; Honda, S; Matsushima, T; Yamaguchi, K1
Berkenstam, A; Carlstedt-Duke, J; Gustafsson, JA; Jörnvall, H; Strömstedt, PE1
Honegger, CG; Kabiersch, A; Krenger, W; Langemann, H; Torhorst, J2
Kohoutek, M; Kolár, Z; Kovarík, J; Krepela, E; Rypka, M; Vicar, J1
Chambon, P; Diemunsch, P; Lepage, P; Rio, MC; Roitsch, C1
Katzenellenbogen, BS; Sheen, YY1
Braunsberg, H; Killen, E; Richardson, SG1
Goriukhina, TA; Misheneva, VS; Parshin, AN1

Reviews

10 review(s) available for cysteine and Breast Neoplasms

ArticleYear
Cysteine Cathepsins in Breast Cancer: Promising Targets for Fluorescence-Guided Surgery.
    Molecular imaging and biology, 2023, Volume: 25, Issue:1

    Topics: Animals; Breast Neoplasms; Cathepsins; Cysteine; Fluorescence; Fluorescent Dyes; Humans; Mice; Neoplasms

2023
Tumor cell- and microenvironment-specific roles of cysteine cathepsins in mouse models of human cancers.
    Biochimica et biophysica acta. Proteins and proteomics, 2020, Volume: 1868, Issue:7

    Topics: Allografts; Animals; Breast Neoplasms; Carcinogenesis; Cathepsin B; Cathepsin L; Cathepsins; Cysteine; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Humans; Intestinal Neoplasms; Mice; Neoplasms; Pancreatic Neoplasms; Skin Neoplasms; Tumor Microenvironment

2020
Activation of Nm23-H1 to suppress breast cancer metastasis via redox regulation.
    Experimental & molecular medicine, 2021, Volume: 53, Issue:3

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cysteine; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Histones; Humans; Neoplasm Metastasis; NM23 Nucleoside Diphosphate Kinases; Oxidation-Reduction

2021
Development of New ADC Technology with Topoisomerase I Inhibitor.
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2017, Volume: 137, Issue:5

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Breast Neoplasms; Camptothecin; Cysteine; Drug Delivery Systems; Drug Discovery; Humans; Immunoconjugates; Molecular Targeted Therapy; Rats; Receptor, ErbB-2; Topoisomerase I Inhibitors; Trastuzumab

2017
Nonessential amino acid metabolism in breast cancer.
    Advances in biological regulation, 2016, Volume: 62

    Topics: Animals; Arginine; Breast Neoplasms; Cysteine; Diet Therapy; Female; Food Deprivation; Glutamic Acid; Glutamine; Glycine; Humans; Metabolic Networks and Pathways; Proline; Serine

2016
Cysteine peptidases and their inhibitors in breast and genital cancer.
    Folia histochemica et cytobiologica, 2010, Sep-30, Volume: 48, Issue:3

    Topics: Breast Neoplasms; Cysteine; Cysteine Proteinase Inhibitors; Endopeptidases; Female; Genital Neoplasms, Female; Humans; Peptide Hydrolases

2010
FD-LC-MS/MS method for determining protein expression and elucidating biochemical events in tissues and cells.
    Biological & pharmaceutical bulletin, 2012, Volume: 35, Issue:9

    Topics: Animals; Brain; Breast Neoplasms; Chromatography, High Pressure Liquid; Chromatography, Liquid; Cysteine; Fluorescence; Liver; Muscle Proteins; Myocardium; Proteins; Proteomics; Tandem Mass Spectrometry

2012
Oxidative stress and cancer pain.
    Canadian journal of physiology and pharmacology, 2013, Volume: 91, Issue:1

    Topics: Bone and Bones; Bone Neoplasms; Breast Neoplasms; Cysteine; Female; Glutamic Acid; Humans; Nociceptive Pain; Oxidative Stress; Reactive Oxygen Species

2013
Oxidation of zinc finger transcription factors: physiological consequences.
    Antioxidants & redox signaling, 2001, Volume: 3, Issue:4

    Topics: Aging; Animals; Antioxidants; Binding Sites; Breast Neoplasms; Chlorocebus aethiops; COS Cells; Cysteine; DNA; DNA-Binding Proteins; Early Growth Response Protein 1; Escherichia coli Proteins; Female; Gene Expression Regulation; HeLa Cells; Humans; Immediate-Early Proteins; Models, Biological; Neoplasm Proteins; Oxidation-Reduction; Oxidative Stress; Oxidoreductases; Protein Binding; Protein Conformation; Receptors, Estrogen; Receptors, Glucocorticoid; Sp1 Transcription Factor; Structure-Activity Relationship; Sulfhydryl Reagents; Superoxides; Transcription Factors; Zinc Fingers

2001
Se-methylselenocysteine: a new compound for chemoprevention of breast cancer.
    Nutrition and cancer, 2001, Volume: 40, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Breast Neoplasms; Cysteine; Disease Models, Animal; Female; Humans; Mammary Neoplasms, Experimental; Organoselenium Compounds; Selenocysteine; Treatment Outcome

2001

Trials

4 trial(s) available for cysteine and Breast Neoplasms

ArticleYear
Safety and efficacy of spleen aminopeptide oral lyophilized powder for improving quality of life and immune response in patients with advanced breast cancer: a multicenter, randomized, double-blind, placebo-controlled clinical trial.
    Anti-cancer drugs, 2021, 11-01, Volume: 32, Issue:10

    Topics: Anilides; Antineoplastic Combined Chemotherapy Protocols; Biological Products; Breast Neoplasms; Cysteine; Double-Blind Method; Female; Humans; Lymphocyte Count; Middle Aged; Quality of Life

2021
Changes in plasma thiol levels induced by different phases of treatment in breast cancer; the role of commercial extract from black chokeberry.
    Molecular and cellular biochemistry, 2013, Volume: 372, Issue:1-2

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Antioxidants; Breast Neoplasms; Carcinoma, Ductal, Breast; Case-Control Studies; Combined Modality Therapy; Cyclophosphamide; Cysteine; Dipeptides; Doxorubicin; Female; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Humans; Middle Aged; Photinia; Plant Extracts; Superoxide Dismutase

2013
hOGG1 Ser326Cys polymorphism and breast cancer risk among Asian women.
    Breast cancer research and treatment, 2003, Volume: 79, Issue:1

    Topics: Adult; Aged; Amino Acid Substitution; Asian People; Breast Neoplasms; Case-Control Studies; Cysteine; DNA Glycosylases; DNA, Neoplasm; Female; Gene Frequency; Genetic Predisposition to Disease; Humans; Japan; Korea; Logistic Models; Middle Aged; Polymorphism, Genetic; Risk Factors; Serine

2003
[Double blind test of L-cysteine for protection against radiation-induced side effects in man (author's transl)].
    Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1977, May-25, Volume: 37, Issue:5

    Topics: Adult; Aged; Breast Neoplasms; Clinical Trials as Topic; Cysteine; Female; Humans; Leukocyte Count; Middle Aged; Radiation Injuries; Radiation-Protective Agents; Uterine Cervical Neoplasms

1977

Other Studies

123 other study(ies) available for cysteine and Breast Neoplasms

ArticleYear
Characterization of Cytosolic Glutathione
    Drug metabolism and disposition: the biological fate of chemicals, 2021, Volume: 49, Issue:12

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chromatography, Liquid; Cysteine; Cytosol; Estrogens; Glutathione Transferase; Hepatobiliary Elimination; Humans; Inactivation, Metabolic; Liver; Protein Isoforms; Receptors, Estrogen

2021
Circular RNA hsa_circ_0103552 Promotes Proliferation, Migration, and Invasion of Breast Cancer Cells through Upregulating Cysteine-Rich Angiogenic Inducer 61 (CYR61) Expression via Sponging MicroRNA-515-5p.
    The Tohoku journal of experimental medicine, 2021, Volume: 255, Issue:2

    Topics: Breast Neoplasms; Cell Proliferation; Cysteine; Cysteine-Rich Protein 61; Female; Humans; MicroRNAs; RNA, Circular

2021
CHMFL-26 is a highly potent irreversible HER2 inhibitor for use in the treatment of HER2-positive and HER2-mutant cancers.
    Acta pharmacologica Sinica, 2022, Volume: 43, Issue:10

    Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cysteine; Drug Resistance, Neoplasm; Female; Humans; Mice; Mutation; Protein Kinase Inhibitors; Receptor, ErbB-2; Xenograft Model Antitumor Assays

2022
Cysteine-rich domain of type III collagen N-propeptide inhibits fibroblast activation by attenuating TGFβ signaling.
    Matrix biology : journal of the International Society for Matrix Biology, 2022, Volume: 109

    Topics: Actins; Breast Neoplasms; Cells, Cultured; Cicatrix; Collagen; Collagen Type III; Cysteine; Female; Fibroblasts; Humans; Myofibroblasts; Transforming Growth Factor beta; Tumor Microenvironment

2022
Daidzein-directed methionine γ-lyase in enzyme prodrug therapy against breast cancer.
    Biochimie, 2022, Volume: 201

    Topics: Animals; Breast Neoplasms; Carbon-Sulfur Lyases; Cysteine; Female; Humans; Isoflavones; Methionine; Mice; Prodrugs; Sulfoxides

2022
A quantitative metabolomics assay targeting 14 intracellular metabolites associated with the methionine transsulfuration pathway using LC-MS/MS in breast cancer cells.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2022, Aug-01, Volume: 1205

    Topics: Breast Neoplasms; Chromatography, Liquid; Cysteine; Cystine; Female; Glutathione; Homocysteine; Humans; Metabolomics; Methionine; Tandem Mass Spectrometry

2022
Biodegradable gellan gum hydrogels loaded with paclitaxel for HER2+ breast cancer local therapy.
    Carbohydrate polymers, 2022, Oct-15, Volume: 294

    Topics: Breast Neoplasms; Cysteine; Female; Humans; Hydrogels; Paclitaxel; Polysaccharides, Bacterial

2022
L-cysteine embedded core-shell ZnO microspheres composed of nanoclusters enhances anticancer activity against liver and breast cancer cells.
    Toxicology in vitro : an international journal published in association with BIBRA, 2022, Volume: 85

    Topics: Apoptosis; Breast Neoplasms; Cell Proliferation; Cysteine; Female; Humans; Liver; MCF-7 Cells; RNA, Messenger; Zinc Oxide

2022
Activity-Based Proteomic Identification of the
    Journal of agricultural and food chemistry, 2022, Nov-23, Volume: 70, Issue:46

    Topics: Antioxidants; Biotin; Breast Neoplasms; Cysteine; Disulfides; Female; Garlic; Humans; Proteomics; Sulfoxides

2022
Chemoproteomic Profiling Reveals that Anticancer Natural Product Dankastatin B Covalently Targets Mitochondrial VDAC3.
    Chembiochem : a European journal of chemical biology, 2023, 07-17, Volume: 24, Issue:14

    Topics: Biological Products; Breast Neoplasms; Cysteine; Female; Humans; Mitochondria; Mitochondrial Membrane Transport Proteins; Voltage-Dependent Anion Channels

2023
Identifying liver metastasis-related hub genes in breast cancer and characterizing
    PeerJ, 2023, Volume: 11

    Topics: Biomarkers; Breast Neoplasms; Calcium-Binding Proteins; Cysteine; Extracellular Matrix Proteins; Female; Humans; Liver Neoplasms; Osteonectin; Prognosis

2023
Prognosis stratification of patients with breast invasive carcinoma based on cysteine metabolism-disulfidptosis affinity.
    Journal of cancer research and clinical oncology, 2023, Volume: 149, Issue:13

    Topics: Breast; Breast Neoplasms; Cysteine; Female; Humans; Nomograms; Prognosis; Tumor Microenvironment

2023
Plasma One-Carbon Metabolism-Related Micronutrients and the Risk of Breast Cancer: Involvement of DNA Methylation.
    Nutrients, 2023, Aug-17, Volume: 15, Issue:16

    Topics: Breast Neoplasms; Carbon; Case-Control Studies; Choline; Cysteine; DNA Methylation; Female; Folic Acid; Humans; Methionine; Micronutrients; Racemethionine; S-Adenosylmethionine; Trace Elements

2023
Dosing Time-Dependent Changes in the Anti-tumor Effect of xCT Inhibitor Erastin in Human Breast Cancer Xenograft Mice.
    Biological & pharmaceutical bulletin, 2019, Volume: 42, Issue:11

    Topics: A549 Cells; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cysteine; Dose-Response Relationship, Drug; Glutathione; HeLa Cells; Hep G2 Cells; Heterografts; Humans; MCF-7 Cells; Mice; Piperazines

2019
Hypoxia Suppresses Cysteine Deprivation-induced Cell Death
    Anticancer research, 2020, Volume: 40, Issue:3

    Topics: Activating Transcription Factor 4; Breast Neoplasms; Cell Death; Cell Hypoxia; Cell Line, Tumor; Cysteine; Female; Humans; Sulfasalazine; Transfection; Up-Regulation

2020
Design and Validation of Linkers for Site-Specific Preparation of Antibody-Drug Conjugates Carrying Multiple Drug Copies Per Cysteine Conjugation Site.
    International journal of molecular sciences, 2020, Sep-19, Volume: 21, Issue:18

    Topics: Antineoplastic Agents; Antineoplastic Agents, Immunological; Breast Neoplasms; Cell Line, Tumor; Cysteine; Drug Screening Assays, Antitumor; Female; Humans; Immunoconjugates

2020
L-Cysteine/AgNO
    Soft matter, 2020, Nov-04, Volume: 16, Issue:42

    Topics: Breast Neoplasms; Cysteine; Female; Humans; MCF-7 Cells; Metal Nanoparticles; Molecular Weight; Silver

2020
The effects of chicken egg white cystatin and proteinase inhibitor on cysteine peptidase-like activity in the sera of patients with breast cancer.
    Advances in clinical and experimental medicine : official organ Wroclaw Medical University, 2021, Volume: 30, Issue:3

    Topics: Animals; Breast Neoplasms; Chickens; Cystatins; Cysteine; Egg White; Humans

2021
Cysteine transporter SLC3A1 promotes breast cancer tumorigenesis.
    Theranostics, 2017, Volume: 7, Issue:4

    Topics: Amino Acid Transport Systems, Basic; Amino Acid Transport Systems, Neutral; Animals; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Cysteine; Disease Models, Animal; Gene Expression Profiling; HEK293 Cells; Heterografts; Humans; Mice, Inbred BALB C; Mice, Nude; Survival Analysis

2017
Vanadium(III)-l-cysteine enhances the sensitivity of murine breast adenocarcinoma cells to cyclophosphamide by promoting apoptosis and blocking angiogenesis.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2017, Volume: 39, Issue:5

    Topics: Adenocarcinoma; Animals; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Coordination Complexes; Cyclophosphamide; Cysteine; Disease Models, Animal; DNA Damage; Drug Resistance, Neoplasm; Female; Humans; Mammary Neoplasms, Animal; Mice; Neovascularization, Pathologic; Oxidative Stress; Reactive Oxygen Species

2017
Cysteine cathepsins B and X promote epithelial-mesenchymal transition of tumor cells.
    European journal of cell biology, 2017, Volume: 96, Issue:6

    Topics: Breast Neoplasms; Cathepsin B; Cathepsin Z; Cell Movement; Cysteine; Epithelial-Mesenchymal Transition; Female; Humans; MCF-7 Cells; Signal Transduction; Transforming Growth Factor beta1

2017
Covalent Ligand Discovery against Druggable Hotspots Targeted by Anti-cancer Natural Products.
    Cell chemical biology, 2017, Nov-16, Volume: 24, Issue:11

    Topics: Amino Acid Sequence; Antineoplastic Agents; Biological Products; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cysteine; Female; Humans; Ligands; MCF-7 Cells; Protein Phosphatase 2; Proteome; Proto-Oncogene Proteins c-akt; Signal Transduction; Withanolides

2017
Oncogenic PI3K promotes methionine dependency in breast cancer cells through the cystine-glutamate antiporter xCT.
    Science signaling, 2017, Dec-19, Volume: 10, Issue:510

    Topics: Amino Acid Transport System y+; Breast Neoplasms; Carcinogenesis; Cell Line; Cell Proliferation; Class I Phosphatidylinositol 3-Kinases; Cysteine; Cystine; Female; Gene Expression; Glutamic Acid; Homocysteine; Humans; Mammary Glands, Human; MCF-7 Cells; Methionine; Mutation

2017
15-Deoxy-Δ
    Cancer letters, 2018, 06-28, Volume: 424

    Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cysteine; Female; Humans; MCF-7 Cells; Mice; Neoplasm Transplantation; Phosphatidylinositol 3-Kinases; Phosphorylation; Prostaglandin D2; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Reactive Oxygen Species; Signal Transduction

2018
Identification and Quantification of Novel Major Metabolites of the Steroidal Aromatase Inhibitor, Exemestane.
    Drug metabolism and disposition: the biological fate of chemicals, 2018, Volume: 46, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Chromatography, Liquid; Cysteine; Female; Glucuronides; Humans; Metabolic Detoxication, Phase II; Middle Aged; Tandem Mass Spectrometry

2018
Self-Assembled Copper-Amino Acid Nanoparticles for in Situ Glutathione "AND" H
    Journal of the American Chemical Society, 2019, 01-16, Volume: 141, Issue:2

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Copper; Cysteine; Female; Glutathione; Humans; Hydrogen Peroxide; Hydroxyl Radical; Metal Nanoparticles; Mice, Inbred BALB C; Mice, Inbred NOD; Mice, SCID; Oxidation-Reduction; Xenograft Model Antitumor Assays

2019
Beta-elemene inhibits breast cancer metastasis through blocking pyruvate kinase M2 dimerization and nuclear translocation.
    Journal of cellular and molecular medicine, 2019, Volume: 23, Issue:10

    Topics: Aerobiosis; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cysteine; ErbB Receptors; Female; Fructosediphosphates; Gene Expression Regulation, Neoplastic; Glucose Transporter Type 1; Glycolysis; Humans; Mice, Inbred BALB C; Mice, Nude; Models, Biological; Neoplasm Invasiveness; Neoplasm Metastasis; Protein Multimerization; Protein Transport; Pyruvate Kinase; Sesquiterpenes; Signal Transduction

2019
Fatigue in patients undergoing radiation therapy: an observational study.
    Minerva medica, 2013, Volume: 104, Issue:2

    Topics: Albumins; Breast Neoplasms; Cysteine; Dietary Supplements; Fatigue; Female; Humans; Lactoferrin; Male; Milk Proteins; Prostatic Neoplasms; Quality of Life; Surveys and Questionnaires; Whey Proteins

2013
Relationship between a point mutation S97C in CK1δ protein and its affect on ATP-binding affinity.
    Journal of biomolecular structure & dynamics, 2014, Volume: 32, Issue:3

    Topics: Adenosine Triphosphate; Breast Neoplasms; Carcinoma, Ductal, Breast; Casein Kinase Idelta; Computer Simulation; Cysteine; Female; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Point Mutation; Serine; Signal Transduction

2014
S-nitrosylation of ERK inhibits ERK phosphorylation and induces apoptosis.
    Scientific reports, 2013, Volume: 3

    Topics: Apoptosis; Blotting, Western; Breast Neoplasms; Cysteine; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Immunoprecipitation; Mutagenesis, Site-Directed; Mutation; Nitric Oxide; Phosphorylation; Signal Transduction; Tumor Cells, Cultured

2013
Improved quenched fluorescent probe for imaging of cysteine cathepsin activity.
    Journal of the American Chemical Society, 2013, Oct-02, Volume: 135, Issue:39

    Topics: Animals; Breast; Breast Neoplasms; Cell Line; Cells, Cultured; Cysteine; Cysteine Proteases; Female; Fluorescent Dyes; Humans; Ketones; Mice; Optical Imaging

2013
Targeting tamoxifen to breast cancer xenograft tumours: preclinical efficacy of folate-attached nanoparticles based on alginate-cysteine/disulphide-bond-reduced albumin.
    Pharmaceutical research, 2014, Volume: 31, Issue:5

    Topics: Albumins; Alginates; Animals; Breast Neoplasms; Cysteine; Disulfides; Folic Acid; Glucuronic Acid; Hexuronic Acids; Humans; MCF-7 Cells; Mice; Mice, Nude; Nanoparticles; Tamoxifen; Xenograft Model Antitumor Assays

2014
A chemoproteomic platform to quantitatively map targets of lipid-derived electrophiles.
    Nature methods, 2014, Volume: 11, Issue:1

    Topics: Amino Acid Sequence; Breast Neoplasms; Catalytic Domain; Cell Line, Tumor; Cysteine; Dose-Response Relationship, Drug; Electrochemistry; Female; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Inhibitory Concentration 50; Lipids; MAP Kinase Kinase Kinases; Mass Spectrometry; Molecular Sequence Data; Oxidative Stress; Prostaglandin D2; Protein Kinases; Protein Processing, Post-Translational; Proteome; Proteomics; Sequence Homology, Amino Acid

2014
Sulphoxythiocarbamates modify cysteine residues in HSP90 causing degradation of client proteins and inhibition of cancer cell proliferation.
    British journal of cancer, 2014, Jan-07, Volume: 110, Issue:1

    Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Breast Neoplasms; Carbamates; Cell Growth Processes; Cell Line, Tumor; Cysteine; Female; HeLa Cells; HSP72 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; MCF-7 Cells; Mice; Mice, Knockout; Molecular Sequence Data; Molecular Targeted Therapy; Neoplasm Proteins; Sulfhydryl Compounds; Sulfoxides; Up-Regulation

2014
Quantitation of human metallothionein isoforms: a family of small, highly conserved, cysteine-rich proteins.
    Molecular & cellular proteomics : MCP, 2014, Volume: 13, Issue:4

    Topics: Alternative Splicing; Breast Neoplasms; Cadmium; Cells, Cultured; Cerebrum; Cysteine; Cytosol; Epithelial Cells; Female; Humans; Kidney; MCF-7 Cells; Metallothionein; Methionine; Organ Specificity; Peptides; Protein Isoforms; Proteomics; Reproducibility of Results; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2014
Investigation of estrogen receptor (ESR1) for breast cancer from traditional Chinese medicine.
    BioMed research international, 2014, Volume: 2014

    Topics: 5-Hydroxytryptophan; Binding Sites; Breast Neoplasms; Computational Biology; Computer Simulation; Crystallography, X-Ray; Cysteine; Databases, Factual; Drug Design; Estrogen Receptor alpha; Female; Humans; Ligands; Medicine, Chinese Traditional; Molecular Docking Simulation; Protein Binding; Protein Conformation; Proteins

2014
Antitumor mechanisms of S-allyl mercaptocysteine for breast cancer therapy.
    BMC complementary and alternative medicine, 2014, Jul-28, Volume: 14

    Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Survival; Cysteine; Female; Humans; MCF-7 Cells

2014
Cysteine rhenium colloid: a novel radiocolloid for identifying sentinel lymph nodes in breast cancer surgery.
    Clinical breast cancer, 2015, Volume: 15, Issue:1

    Topics: Aged; Breast Neoplasms; Colloids; Cysteine; Female; Humans; Intraoperative Period; Lymphatic Metastasis; Mastectomy; Middle Aged; Radioisotopes; Radionuclide Imaging; Radiopharmaceuticals; Retrospective Studies; Rhenium; Sentinel Lymph Node Biopsy

2015
Patched targeting peptides for imaging and treatment of hedgehog positive breast tumors.
    BioMed research international, 2014, Volume: 2014

    Topics: Amino Acid Sequence; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cysteine; Diagnostic Imaging; Female; Hedgehog Proteins; Humans; Molecular Sequence Data; Molecular Targeted Therapy; Patched Receptors; Patched-1 Receptor; Peptides; Rats, Inbred F344; Receptors, Cell Surface; Spheroids, Cellular; Staining and Labeling; Technetium; Xenograft Model Antitumor Assays

2014
Mechanism-Based Pharmacokinetic/Pharmacodynamic Model for THIOMAB™ Drug Conjugates.
    Pharmaceutical research, 2015, Volume: 32, Issue:6

    Topics: Administration, Intravenous; Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Antineoplastic Agents; Biological Availability; Breast Neoplasms; Cysteine; Female; Male; Metabolic Clearance Rate; Mice, Nude; Mice, SCID; Models, Biological; Neoplasm Transplantation; Sulfhydryl Compounds; Trastuzumab

2015
Involvement of de novo synthesized palmitate and mitochondrial EGFR in EGF induced mitochondrial fusion of cancer cells.
    Cell cycle (Georgetown, Tex.), 2014, Volume: 13, Issue:15

    Topics: Breast Neoplasms; Cell Line, Tumor; Cysteine; Drug Resistance; Epidermal Growth Factor; ErbB Receptors; Fatty Acid Synthase, Type I; Female; Humans; Male; Mitochondria; Mitochondrial Dynamics; Mitochondrial Proteins; Palmitates; Prohibitins; Prostatic Neoplasms; Protein Array Analysis; Protein Kinase Inhibitors; Protein-Tyrosine Kinases

2014
Dimethyl Fumarate Inhibits the Nuclear Factor κB Pathway in Breast Cancer Cells by Covalent Modification of p65 Protein.
    The Journal of biological chemistry, 2016, Feb-12, Volume: 291, Issue:7

    Topics: Active Transport, Cell Nucleus; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cysteine; Dimethyl Fumarate; Female; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Mice, Nude; Neoplasm Proteins; Neoplastic Stem Cells; NF-kappa B; Random Allocation; Signal Transduction; Transcription Factor RelA; Tumor Burden; Xenograft Model Antitumor Assays

2016
Downregulation of importin-9 protects MCF-7 cells against apoptosis induced by the combination of garlic-derived alliin and paclitaxel.
    Oncology reports, 2016, Volume: 35, Issue:5

    Topics: Actins; Active Transport, Cell Nucleus; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cofilin 1; Cysteine; Down-Regulation; Drug Screening Assays, Antitumor; Drug Synergism; Female; Garlic; Humans; Karyopherins; MCF-7 Cells; Paclitaxel

2016
Inhibition of DHHC20-Mediated EGFR Palmitoylation Creates a Dependence on EGFR Signaling.
    Molecular cell, 2016, 05-05, Volume: 62, Issue:3

    Topics: Acyltransferases; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Death; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cysteine; Endocytosis; Epidermal Growth Factor; ErbB Receptors; Gefitinib; GRB2 Adaptor Protein; HEK293 Cells; Humans; Lipoylation; Mass Spectrometry; Mice; Mutation; NIH 3T3 Cells; Protein Conformation; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Protein Transport; Proteolysis; Quinazolines; RNA Interference; Signal Transduction; Structure-Activity Relationship; Transfection

2016
Preparation and evaluation of the tumor-specific antigen-derived synthetic mucin 1 peptide: A potential candidate for the targeting of breast carcinoma.
    Nuclear medicine and biology, 2016, Volume: 43, Issue:7

    Topics: Amino Acid Sequence; Animals; Breast Neoplasms; Cell Transformation, Neoplastic; Cysteine; Drug Stability; Half-Life; Humans; MCF-7 Cells; Mice; Mucin-1; Peptide Fragments; Protein Transport; Technetium; Tissue Distribution

2016
Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine.
    Cell, 2016, Jun-30, Volume: 166, Issue:1

    Topics: Amino Acid Transport System y+; Animals; Breast Neoplasms; Cysteine; Glutamic Acid; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Hypoxia-Inducible Factor-Proline Dioxygenases; MCF-7 Cells; Mice; Paracrine Communication; Triple Negative Breast Neoplasms

2016
Biosensing breast cancer cells based on a three-dimensional TIO
    Biosensors & bioelectronics, 2017, Jun-15, Volume: 92

    Topics: Biosensing Techniques; Breast; Breast Neoplasms; Cell Line, Tumor; Cysteine; Dielectric Spectroscopy; Female; Humans; Immobilized Proteins; Lectins; Membranes, Artificial; Nanostructures; Point-of-Care Systems; Titanium; Transducers

2017
Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth.
    Nature medicine, 2017, Volume: 23, Issue:1

    Topics: Animals; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cystathionine gamma-Lyase; Cysteine; Cystine; Female; Glutathione; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Macaca fascicularis; Male; Mice; Mice, Knockout; Mice, Transgenic; Neoplasm Transplantation; Oxidative Stress; Polyethylene Glycols; Prostatic Neoplasms; Reactive Oxygen Species; Tumor Suppressor Protein p53

2017
Cysteine-linked dimerization of BST-2 confers anoikis resistance to breast cancer cells by negating proapoptotic activities to promote tumor cell survival and growth.
    Cell death & disease, 2017, 03-16, Volume: 8, Issue:3

    Topics: Animals; Anoikis; Antigens, CD; Apoptosis; Apoptosis Regulatory Proteins; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cysteine; Dimerization; Female; Gene Expression Regulation, Neoplastic; GPI-Linked Proteins; GRB2 Adaptor Protein; Humans; MAP Kinase Signaling System; MCF-7 Cells; Membrane Proteins; Mice; Mice, Inbred BALB C; Proteasome Endopeptidase Complex

2017
Differential sensitivity of various human tumour-derived cell types to apoptosis by organic derivatives of selenium.
    The British journal of nutrition, 2009, Volume: 101, Issue:2

    Topics: Adenocarcinoma; Adolescent; Adult; Animals; Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Cysteine; Epithelial Cells; Female; Humans; Liver Neoplasms; Male; Melanoma; Middle Aged; Neoplasms; Neuroectodermal Tumors, Primitive, Peripheral; Organoselenium Compounds; Selenium Compounds; Selenocysteine; Selenomethionine; Skin Neoplasms

2009
Mitochondria-targeted chemotherapeutics: the rational design of gold(I) N-heterocyclic carbene complexes that are selectively toxic to cancer cells and target protein selenols in preference to thiols.
    Journal of the American Chemical Society, 2008, Sep-24, Volume: 130, Issue:38

    Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cysteine; Drug Design; Drug Screening Assays, Antitumor; Gold; Heterocyclic Compounds; Humans; Methane; Mitochondria; Mitochondrial Proteins; Organometallic Compounds; Selenocysteine; Thioredoxin-Disulfide Reductase

2008
Combination of methylselenocysteine with tamoxifen inhibits MCF-7 breast cancer xenografts in nude mice through elevated apoptosis and reduced angiogenesis.
    Breast cancer research and treatment, 2009, Volume: 118, Issue:1

    Topics: Adenocarcinoma; Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Breast Neoplasms; Cell Division; Cyclin D1; Cysteine; Drug Synergism; Estradiol; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Neovascularization, Pathologic; Organoselenium Compounds; Random Allocation; Receptors, Progesterone; Selenocysteine; Specific Pathogen-Free Organisms; Tamoxifen; Xenograft Model Antitumor Assays

2009
Chemopreventive doses of methylselenocysteine alter circadian rhythm in rat mammary tissue.
    Cancer prevention research (Philadelphia, Pa.), 2008, Volume: 1, Issue:2

    Topics: Animals; Breast Neoplasms; Carcinoma; Cell Cycle Proteins; Chemoprevention; Circadian Rhythm; Cysteine; Dose-Response Relationship, Drug; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Mammary Glands, Animal; Methylnitrosourea; Nuclear Proteins; Oligonucleotide Array Sequence Analysis; Organoselenium Compounds; Period Circadian Proteins; Rats; Rats, Inbred F344; Selenium; Selenocysteine; Specific Pathogen-Free Organisms

2008
Genome-free viral capsids as multivalent carriers for taxol delivery.
    Angewandte Chemie (International ed. in English), 2009, Volume: 48, Issue:50

    Topics: Antineoplastic Agents; Breast Neoplasms; Capsid; Capsid Proteins; Cell Line, Tumor; Cell Survival; Cross-Linking Reagents; Cysteine; Drug Carriers; Female; Genome, Viral; Humans; Paclitaxel

2009
Plasma homocysteine and cysteine and risk of breast cancer in women.
    Cancer research, 2010, Mar-15, Volume: 70, Issue:6

    Topics: Breast Neoplasms; Case-Control Studies; Cysteine; Female; Folic Acid; Homocysteine; Humans; Middle Aged; Prospective Studies; Pyridoxal Phosphate; Vitamin B 12

2010
Synthesis of (99m)Tc-EC-AMT as an imaging probe for amino acid transporter systems in breast cancer.
    Nuclear medicine communications, 2010, Volume: 31, Issue:8

    Topics: alpha-Methyltyrosine; Amino Acid Transport Systems; Animals; Biological Transport; Breast Neoplasms; Cell Line, Tumor; Chelating Agents; Cysteine; Female; Molecular Imaging; Organotechnetium Compounds; Positron-Emission Tomography; Rats

2010
Piceatannol, a catechol-type polyphenol, inhibits phorbol ester-induced NF-{kappa}B activation and cyclooxygenase-2 expression in human breast epithelial cells: cysteine 179 of IKK{beta} as a potential target.
    Carcinogenesis, 2010, Volume: 31, Issue:8

    Topics: Anticarcinogenic Agents; Blotting, Western; Breast; Breast Neoplasms; Cell Culture Techniques; Cell Division; Cell Line, Tumor; Cyclooxygenase 2; Cysteine; Epithelial Cells; Female; Flavonoids; Gene Expression Regulation, Enzymologic; Humans; I-kappa B Kinase; NF-kappa B; Phenols; Phorbol Esters; Polyphenols; Resveratrol; Stilbenes; Wound Healing

2010
Modulation of gene expression and tumor cell growth by redox modification of STAT3.
    Cancer research, 2010, Oct-15, Volume: 70, Issue:20

    Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Breast Neoplasms; Cell Division; Conserved Sequence; Cysteine; Female; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Molecular Sequence Data; Oxidative Stress; Species Specificity; STAT1 Transcription Factor; STAT3 Transcription Factor; Transplantation Chimera; Vertebrates

2010
BCL-2 (-938C > A) polymorphism is associated with breast cancer susceptibility.
    BMC medical genetics, 2011, Apr-01, Volume: 12

    Topics: Adult; Aged; Alanine; Biomarkers, Tumor; Blotting, Western; Breast Neoplasms; Case-Control Studies; Cell Line, Tumor; Cysteine; Female; Gene Expression Regulation, Neoplastic; Genes, bcl-2; Genetic Predisposition to Disease; Genotype; Humans; Immunohistochemistry; Logistic Models; Lymphatic Metastasis; Middle Aged; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Proto-Oncogene Proteins c-bcl-2; Risk Assessment; Risk Factors

2011
Sulfur amino acid metabolism in doxorubicin-resistant breast cancer cells.
    Toxicology and applied pharmacology, 2011, Aug-15, Volume: 255, Issue:1

    Topics: Amino Acids, Sulfur; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bleomycin; Breast Neoplasms; Cell Line, Tumor; Cysteine; Doxorubicin; Drug Resistance, Neoplasm; Female; Glutathione; Humans; Methionine; Vitamin K 3

2011
Non-cysteine linked MUC1 cytoplasmic dimers are required for Src recruitment and ICAM-1 binding induced cell invasion.
    Molecular cancer, 2011, Jul-28, Volume: 10

    Topics: Breast Neoplasms; Carcinoma; Cell Line, Tumor; Cysteine; Female; HEK293 Cells; Humans; Intercellular Adhesion Molecule-1; Models, Biological; Mucin-1; Neoplasm Invasiveness; Protein Binding; Protein Multimerization; RNA, Small Interfering; src-Family Kinases

2011
Complement activation and cell uptake responses toward polymer-functionalized protein nanocapsules.
    Biomacromolecules, 2012, Apr-09, Volume: 13, Issue:4

    Topics: Breast Neoplasms; Cell Line, Tumor; Complement Activation; Cysteine; Dihydrolipoyllysine-Residue Acetyltransferase; Female; Humans; Macrophages; Nanocapsules; Polyethylene Glycols; Protein Transport; Surface Properties

2012
Chalcone-based small-molecule inhibitors attenuate malignant phenotype via targeting deubiquitinating enzymes.
    Cell cycle (Georgetown, Tex.), 2012, 05-01, Volume: 11, Issue:9

    Topics: Antineoplastic Agents; Apoptosis; Benzylidene Compounds; Boronic Acids; Bortezomib; Breast Neoplasms; Catalytic Domain; Cell Cycle Checkpoints; Cell Proliferation; Cell Survival; Chalcone; Cyclin D1; Cysteine; Dose-Response Relationship, Drug; Endopeptidases; Female; HeLa Cells; Humans; Ovarian Neoplasms; Phenotype; Piperidones; Protease Inhibitors; Proteasome Endopeptidase Complex; Pyrazines; Tumor Suppressor Protein p53; Ubiquitin Thiolesterase; Ubiquitins

2012
Development of (99m)Tc-EC-tyrosine for early detection of breast cancer tumor response to the anticancer drug melphalan.
    Academic radiology, 2013, Volume: 20, Issue:1

    Topics: Amino Acid Transport System y+L; Animals; Breast Neoplasms; Chelating Agents; Cysteine; Dose-Response Relationship, Drug; Female; Immunohistochemistry; Ki-67 Antigen; Melphalan; Neoplasm Proteins; Organotechnetium Compounds; Radionuclide Imaging; Rats; Rats, Inbred F344; Tissue Distribution; Treatment Outcome; Tyrosine

2013
Elevation of cysteine consumption in tamoxifen-resistant MCF-7 cells.
    Biochemical pharmacology, 2013, Jan-15, Volume: 85, Issue:2

    Topics: Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Cystathionine gamma-Lyase; Cysteine; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Glutamate-Cysteine Ligase; Glutathione; Humans; Membrane Transport Modulators; Methionine; Methylation; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Tamoxifen; Taurine; Up-Regulation

2013
Maintenance of S-nitrosothiol homeostasis plays an important role in growth suppression of estrogen receptor-positive breast tumors.
    Breast cancer research : BCR, 2012, Dec-05, Volume: 14, Issue:6

    Topics: Antineoplastic Agents, Hormonal; Antirheumatic Agents; Auranofin; Benzothiazoles; Breast Neoplasms; CD24 Antigen; Cell Proliferation; Cell Survival; Cyclin D1; Cysteine; Estradiol; Estrogen Receptor alpha; Extracellular Signal-Regulated MAP Kinases; Female; Fulvestrant; Homeostasis; Humans; Hyaluronan Receptors; MCF-7 Cells; Phosphorylation; Proto-Oncogene Proteins c-akt; RNA Interference; RNA, Messenger; RNA, Small Interfering; S-Nitrosothiols; Spheroids, Cellular; Thioredoxin-Disulfide Reductase; Toluene; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2012
Induction of histone acetylation and inhibition of growth of mouse erythroleukemia cells by S-allylmercaptocysteine.
    Nutrition and cancer, 2002, Volume: 43, Issue:1

    Topics: Acetylation; Acetyltransferases; Allyl Compounds; Animals; Antineoplastic Agents; Breast Neoplasms; Colonic Neoplasms; Cysteine; Disulfides; Electrophoresis, Polyacrylamide Gel; Female; Histone Acetyltransferases; Histone Deacetylases; Histones; Humans; Leukemia, Erythroblastic, Acute; Leupeptins; Mice; Saccharomyces cerevisiae Proteins; Sulfinic Acids; Tumor Cells, Cultured

2002
Assessment of epidermal growth factor receptor with 99mTc-ethylenedicysteine-C225 monoclonal antibody.
    Anti-cancer drugs, 2003, Volume: 14, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Breast Neoplasms; Cell Line; Cetuximab; Cysteine; ErbB Receptors; Female; Humans; Mice; Mice, Nude; Rats; Technetium; Tissue Distribution

2003
Small, novel proteins from the mistletoe Phoradendron tomentosum exhibit highly selective cytotoxicity to human breast cancer cells.
    Cellular and molecular life sciences : CMLS, 2003, Volume: 60, Issue:1

    Topics: Amino Acid Sequence; Antineoplastic Agents; Breast Neoplasms; Carcinoma; Cysteine; Humans; Mistletoe; Molecular Sequence Data; Molecular Weight; Plant Extracts; Plant Leaves; Plant Proteins; Sequence Alignment; Tumor Cells, Cultured

2003
Essential cysteine-alkylation strategies to monitor structurally altered estrogen receptor as found in oxidant-stressed breast cancers.
    Analytical biochemistry, 2003, Sep-01, Volume: 320, Issue:1

    Topics: Alkylating Agents; Alkylation; Amino Acid Sequence; Breast Neoplasms; Cysteine; Endopeptidases; Female; Humans; Molecular Sequence Data; Oxidative Stress; Receptors, Estrogen; Spectrometry, Mass, Electrospray Ionization

2003
A prospective study of plasma total cysteine and risk of breast cancer.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2003, Volume: 12, Issue:11 Pt 1

    Topics: Adult; Aged; Body Composition; Breast Neoplasms; Case-Control Studies; Chemoprevention; Cysteine; Female; Humans; Incidence; Middle Aged; Nurses; Prospective Studies; Regression Analysis; Risk Factors

2003
Peroxynitrite irreversibly inactivates the human xenobiotic-metabolizing enzyme arylamine N-acetyltransferase 1 (NAT1) in human breast cancer cells: a cellular and mechanistic study.
    The Journal of biological chemistry, 2004, Feb-27, Volume: 279, Issue:9

    Topics: Arylamine N-Acetyltransferase; Breast Neoplasms; Cysteine; Dithiothreitol; Enzyme Inhibitors; Glutathione; Humans; Isoenzymes; Kinetics; Molsidomine; Oxidation-Reduction; Peroxynitrous Acid; Recombinant Proteins; Tumor Cells, Cultured

2004
Agonist-dependent and agonist-independent transactivations of the human constitutive androstane receptor are modulated by specific amino acid pairs.
    The Journal of biological chemistry, 2004, Aug-06, Volume: 279, Issue:32

    Topics: Amino Acid Sequence; Animals; Binding Sites; Breast Neoplasms; Constitutive Androstane Receptor; Cysteine; Dimerization; Drug Stability; Glutamic Acid; Humans; Isoleucine; Leucine; Lysine; Mice; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Receptors, Calcitriol; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Sequence Alignment; Signal Transduction; Structure-Activity Relationship; Transcription Factors; Transcriptional Activation; Transfection; Tumor Cells, Cultured

2004
A STAT3 dimer formed by inter-chain disulphide bridging during oxidative stress.
    Biochemical and biophysical research communications, 2004, Sep-24, Volume: 322, Issue:3

    Topics: Acute-Phase Proteins; B-Lymphocytes; Breast Neoplasms; Cell Line; Cell Line, Tumor; Cysteine; Dimerization; Disulfides; DNA-Binding Proteins; Humans; Kidney; Oxidative Stress; Plasmids; Recombinant Proteins; STAT3 Transcription Factor; Trans-Activators; Transfection

2004
Mutation screening of the BARD1 gene: evidence for involvement of the Cys557Ser allele in hereditary susceptibility to breast cancer.
    Journal of medical genetics, 2004, Volume: 41, Issue:9

    Topics: Alleles; Amino Acid Sequence; Breast Neoplasms; Cysteine; DNA Mutational Analysis; Female; Finland; Genetic Predisposition to Disease; Genetic Testing; Humans; Male; Middle Aged; Molecular Sequence Data; Mutation; Ovarian Neoplasms; Pedigree; Serine; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases

2004
The MUC1 SEA module is a self-cleaving domain.
    The Journal of biological chemistry, 2005, Sep-30, Volume: 280, Issue:39

    Topics: Agrin; Alternative Splicing; Amino Acid Sequence; Amino Acid Substitution; Animals; Antigens; Antigens, Neoplasm; Base Sequence; Breast Neoplasms; Cell Line; Cell Line, Tumor; Cysteine; Enteropeptidase; Enzyme-Linked Immunosorbent Assay; Female; Glycoproteins; Humans; Hydrolysis; Hydroxylamine; Male; Mice; Models, Biological; Molecular Sequence Data; Mucin-1; Mucins; Protein Isoforms; Protein Processing, Post-Translational; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sea Urchins; Spermatozoa; Threonine

2005
Human Kruppel-like factor 5 is a target of the E3 ubiquitin ligase WWP1 for proteolysis in epithelial cells.
    The Journal of biological chemistry, 2005, Dec-16, Volume: 280, Issue:50

    Topics: Amino Acid Motifs; Blotting, Western; Breast Neoplasms; Catalysis; Cell Line, Tumor; Cysteine; DNA; Epithelial Cells; Female; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Glutathione Transferase; Humans; Immunoprecipitation; Kruppel-Like Transcription Factors; Luciferases; Male; Microscopy, Confocal; Microscopy, Fluorescence; Neoplasms; Plasmids; Prostatic Neoplasms; Proteasome Endopeptidase Complex; Protein Binding; Protein Biosynthesis; Protein Structure, Tertiary; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Small Interfering; Time Factors; Transcriptional Activation; Transfection; Ubiquitin; Ubiquitin-Protein Ligases

2005
Role of Cys-603 in dimer/oligomer formation of the breast cancer resistance protein BCRP/ABCG2.
    Cancer science, 2005, Volume: 96, Issue:12

    Topics: Amino Acid Sequence; Amino Acid Substitution; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Cysteine; Dimerization; Drug Resistance, Multiple; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; Genetic Vectors; Humans; Neoplasm Proteins; Protein Conformation; Reverse Transcriptase Polymerase Chain Reaction; Transfection

2005
Scintigraphic images of breast cancer with Tc-99m cysteine.
    Clinical nuclear medicine, 2006, Volume: 31, Issue:6

    Topics: Adult; Breast Neoplasms; Cysteine; Female; Humans; Middle Aged; Radionuclide Imaging; Radiopharmaceuticals; Technetium

2006
Interleukin 6 G-174 C polymorphism and breast cancer risk.
    European journal of epidemiology, 2006, Volume: 21, Issue:5

    Topics: Aged; Aged, 80 and over; Breast Neoplasms; Cysteine; Female; Genetic Predisposition to Disease; Genotype; Glycine; Humans; Interleukin-6; Middle Aged; Polymorphism, Genetic; Risk Factors

2006
The T393C polymorphism in the gene GNAS1 of G protein is associated with survival of patients with invasive breast carcinoma.
    Breast cancer research and treatment, 2007, Volume: 105, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Chromogranins; Cysteine; Female; GTP-Binding Protein alpha Subunits, Gs; Humans; Middle Aged; Neoplasm Invasiveness; Polymorphism, Single Nucleotide; Survival Rate; Threonine

2007
15-deoxy-Delta12,14-prostaglandin J2 inhibits transcriptional activity of estrogen receptor-alpha via covalent modification of DNA-binding domain.
    Cancer research, 2007, Mar-15, Volume: 67, Issue:6

    Topics: Amino Acid Sequence; Breast Neoplasms; Cell Line, Tumor; Cysteine; DNA, Neoplasm; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Humans; Molecular Sequence Data; PPAR gamma; Prostaglandin D2; Protein Structure, Tertiary; Transcriptional Activation; Transfection; Zinc Fingers

2007
Synthesis of the next-generation therapeutic antibodies that combine cell targeting and antibody-catalyzed prodrug activation.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Mar-27, Volume: 104, Issue:13

    Topics: Antibodies; Antibodies, Catalytic; Breast Neoplasms; Cell Line, Tumor; Chemistry, Pharmaceutical; Cysteine; Doxorubicin; Drug Design; Flow Cytometry; Humans; Integrin alphaVbeta3; Models, Chemical; Prodrugs; Protein Binding; Sulfides

2007
Identification of arsenic-binding proteins in human breast cancer cells.
    Cancer letters, 2007, Sep-18, Volume: 255, Issue:1

    Topics: Antineoplastic Agents; Arsenic; Biotin; Breast Neoplasms; Carrier Proteins; Cell Line, Tumor; Cysteine; Humans; Models, Chemical; Models, Molecular; Molecular Conformation; Protein Binding; Pyruvate Kinase; Tubulin

2007
Estrogen-dependent regulation of Eg5 in breast cancer cells.
    Anti-cancer drugs, 2007, Volume: 18, Issue:7

    Topics: Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cysteine; Dose-Response Relationship, Drug; Down-Regulation; Estradiol; Estrogen Antagonists; Estrogens; Female; Flow Cytometry; Fulvestrant; Humans; Inhibitory Concentration 50; Kinesins; Mitosis; Pyrimidines; Receptors, Estrogen; Signal Transduction; Thiones; Up-Regulation

2007
S731 in the transactivation domain modulates STAT5b activity.
    Biochemical and biophysical research communications, 2007, Nov-03, Volume: 362, Issue:4

    Topics: Breast Neoplasms; Cell Line, Tumor; Cysteine; Gene Expression Regulation; Humans; Protein Structure, Tertiary; STAT5 Transcription Factor; Transcriptional Activation; Tyrosine

2007
Subchronic oral toxicity studies of Se-methylselenocysteine, an organoselenium compound for breast cancer prevention.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2008, Volume: 46, Issue:3

    Topics: Administration, Oral; Animals; Anticarcinogenic Agents; Breast Neoplasms; Cysteine; Dogs; Female; Liver; Male; Organoselenium Compounds; Rats; Selenocysteine

2008
S-Allylcysteine reduces breast tumor cell adhesion and invasion.
    Biochemical and biophysical research communications, 2008, Mar-07, Volume: 367, Issue:2

    Topics: Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cysteine; Extracellular Matrix Proteins; Humans; Neoplasm Invasiveness

2008
2-[(1-methylpropyl)dithio]-1H-imidazole inhibits tubulin polymerization through cysteine oxidation.
    Molecular cancer therapeutics, 2008, Volume: 7, Issue:1

    Topics: Breast Neoplasms; Cell Survival; Cells, Cultured; Cysteine; Disulfides; Ficain; Humans; Imidazoles; Microtubules; Molecular Structure; Oxidation-Reduction; Papain; Protease Inhibitors; RNA, Small Interfering; Sensitivity and Specificity; Thioredoxins; Tubulin

2008
[Effects of Se-methylselenocysteine on biological behavior of and matrix metalloproteinase-2 expression in human breast cancer MDA-MB-231 cells].
    Ai zheng = Aizheng = Chinese journal of cancer, 2008, Volume: 27, Issue:2

    Topics: Anticarcinogenic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cysteine; Female; Humans; Matrix Metalloproteinase 2; Organoselenium Compounds; RNA, Messenger; S Phase; Selenocysteine

2008
[Frequency of 5382insC mutation of the BRCA1 gene].
    Voprosy onkologii, 2008, Volume: 54, Issue:1

    Topics: Adult; Bashkiria; Breast Neoplasms; Cysteine; DNA Mutational Analysis; Female; Gene Duplication; Gene Frequency; Genes, BRCA1; Humans; Middle Aged; Mutagenesis, Insertional

2008
The BARD1 Cys557Ser polymorphism and breast cancer risk: an Australian case-control and family analysis.
    Breast cancer research and treatment, 2009, Volume: 115, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Australia; Breast Neoplasms; Case-Control Studies; Cysteine; Family Health; Gene Expression Regulation, Neoplastic; Humans; Middle Aged; Polymorphism, Genetic; Risk; Serine; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases

2009
The effects of naturally occurring metabolites (L-cysteine, vitamin C) on cultured human cells exposed to smoke of tobacco or marijuana cigarettes.
    Cytometry, 1984, Volume: 5, Issue:4

    Topics: Adult; Ascorbic Acid; Breast Neoplasms; Cannabis; Cell Line; Cells, Cultured; Cysteine; DNA; Female; Fetus; Humans; Lung; Nicotiana; Plants, Toxic; Pregnancy; Smoke

1984
Characterization of prenylcysteines that interact with P-glycoprotein and inhibit drug transport in tumor cells.
    The Journal of biological chemistry, 1995, Sep-29, Volume: 270, Issue:39

    Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Breast Neoplasms; Cell Line; Cell Membrane; Cysteine; Drug Resistance, Multiple; Female; Humans; Kinetics; Recombinant Proteins; Spodoptera; Structure-Activity Relationship; Transfection; Tumor Cells, Cultured

1995
Inhibition of AP-1 binding and transcription by gold and selenium involving conserved cysteine residues in Jun and Fos.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, May-09, Volume: 92, Issue:10

    Topics: Amino Acid Sequence; Binding Sites; Breast Neoplasms; Cell Line; Chloramphenicol O-Acetyltransferase; Conserved Sequence; Cysteine; Dose-Response Relationship, Drug; Gold; Gold Sodium Thiomalate; Humans; Kinetics; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Sodium Selenite; Transcription Factor AP-1; Transcription Factors; Transfection; Tumor Cells, Cultured

1995
Plasma levels of the atherogenic amino acid homocysteine in post-menopausal women with breast cancer treated with tamoxifen.
    International journal of cancer, 1995, Jan-27, Volume: 60, Issue:3

    Topics: Aged; Arteriosclerosis; Breast Neoplasms; Cholesterol; Cysteine; Female; Folic Acid; Homocysteine; Humans; Menopause; Middle Aged; Tamoxifen; Time Factors; Vitamin B 12

1995
Cloning and characterization of a human Mac-2-binding protein, a new member of the superfamily defined by the macrophage scavenger receptor cysteine-rich domain.
    The Journal of biological chemistry, 1993, Jul-05, Volume: 268, Issue:19

    Topics: Amino Acid Sequence; Animals; Antigens, Neoplasm; Base Sequence; Biomarkers, Tumor; Breast Neoplasms; Carrier Proteins; Cell Line; Cloning, Molecular; Cysteine; DNA; Female; Gene Library; Glycoproteins; Humans; Milk, Human; Molecular Sequence Data; Monocytes; Multigene Family; Oligodeoxyribonucleotides; Receptors, Cell Surface; Receptors, Immunologic; Receptors, Scavenger; Recombinant Proteins; Sequence Homology, Amino Acid; Transfection; Tumor Cells, Cultured

1993
D-penicillamine causes free radical-dependent inactivation of activator protein-1 DNA binding.
    Molecular pharmacology, 1996, Volume: 50, Issue:3

    Topics: Breast Neoplasms; Cell Nucleus; Cysteine; DNA, Neoplasm; Female; Free Radicals; Humans; Hydrogen Peroxide; Iron; Kinetics; Nuclear Proteins; Penicillamine; Polydeoxyribonucleotides; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Transcription Factor AP-1; Tumor Cells, Cultured

1996
A20, an inhibitor of cell death, self-associates by its zinc finger domain.
    FEBS letters, 1996, Apr-08, Volume: 384, Issue:1

    Topics: Base Sequence; Binding Sites; Breast Neoplasms; Cell Death; Cell Line; Cloning, Molecular; Cysteine; DNA Primers; DNA-Binding Proteins; Female; Gene Expression; Humans; Intracellular Signaling Peptides and Proteins; Molecular Sequence Data; Nuclear Proteins; Polymerase Chain Reaction; Protein Binding; Protein Biosynthesis; Proteins; Recombinant Fusion Proteins; Recombinant Proteins; Tumor Cells, Cultured; Tumor Necrosis Factor alpha-Induced Protein 3; Tumor Necrosis Factor-alpha; Zinc Fingers

1996
Production and comparison of mature single-domain 'trefoil' peptides pNR-2/pS2 Cys58 and pNR-2/pS2 Ser58.
    The Biochemical journal, 1995, Jun-15, Volume: 308 ( Pt 3)

    Topics: Amino Acid Sequence; Blotting, Western; Breast Neoplasms; Chromatography, Gel; Chromatography, Ion Exchange; Cysteine; Dithiothreitol; Electrophoresis, Polyacrylamide Gel; Glutathione; Humans; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Mutation; Neoplasm Proteins; Peptides; Plasmids; Polymerase Chain Reaction; Proteins; Recombinant Proteins; Serine; Trefoil Factor-1; Tumor Suppressor Proteins

1995
Transfection with human thioredoxin increases cell proliferation and a dominant-negative mutant thioredoxin reverses the transformed phenotype of human breast cancer cells.
    Cancer research, 1996, Dec-15, Volume: 56, Issue:24

    Topics: 3T3 Cells; Animals; Breast Neoplasms; Cell Division; Cell Transformation, Neoplastic; Cysteine; Genetic Vectors; Humans; Mice; Mutation; Neoplasm Proteins; Peptide Fragments; Phenotype; Serine; Thioredoxins; Transfection; Tumor Cells, Cultured

1996
S-allylmercaptocysteine inhibits cell proliferation and reduces the viability of erythroleukemia, breast, and prostate cancer cell lines.
    Nutrition and cancer, 1997, Volume: 27, Issue:2

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Division; Cell Survival; Cysteine; Humans; Leukemia, Erythroblastic, Acute; Male; Prostatic Neoplasms; Tumor Cells, Cultured

1997
Accumulation of 99mTc-HMPAO and 99mTc-ECD in rodent and human breast tumor cell lines in vitro.
    Annals of nuclear medicine, 1997, Volume: 11, Issue:2

    Topics: Animals; Breast Neoplasms; Cysteine; Female; Humans; Organotechnetium Compounds; Oximes; Radionuclide Imaging; Rats; Species Specificity; Technetium Tc 99m Exametazime; Tumor Cells, Cultured

1997
Dominant-negative Jun N-terminal protein kinase (JNK-1) inhibits metabolic oxidative stress during glucose deprivation in a human breast carcinoma cell line.
    Free radical biology & medicine, 2000, Feb-15, Volume: 28, Issue:4

    Topics: Breast Neoplasms; Cell Death; Cell Survival; Cysteine; Dipeptides; Doxorubicin; Drug Resistance, Multiple; Enzyme Activation; Female; Glucose; Glutathione; Humans; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Oxidative Stress; Recombinant Proteins; Transfection; Tumor Cells, Cultured

2000
The cysteine-rich domain of human ADAM 12 supports cell adhesion through syndecans and triggers signaling events that lead to beta1 integrin-dependent cell spreading.
    The Journal of cell biology, 2000, May-29, Volume: 149, Issue:5

    Topics: Actins; ADAM Proteins; ADAM12 Protein; Animals; Antibodies, Monoclonal; Breast Neoplasms; Cell Adhesion; Cell Size; Chick Embryo; Chondrocytes; Colonic Neoplasms; Cysteine; Cytoskeleton; Humans; Integrin beta1; Magnesium; Membrane Glycoproteins; Membrane Proteins; Mesoderm; Metalloendopeptidases; Mice; Mice, Inbred Strains; Muscle, Skeletal; Osteoblasts; Osteosarcoma; Protein Structure, Tertiary; Proteoglycans; Receptor Cross-Talk; Rhabdomyosarcoma; Signal Transduction; Stress, Mechanical; Syndecans; Tumor Cells, Cultured

2000
Intake of fruits, vegetables, folic acid and related nutrients and risk of breast cancer in postmenopausal women.
    Public health nutrition, 1998, Volume: 1, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Breast Neoplasms; Case-Control Studies; Cysteine; Diet; Europe; Female; Folic Acid; Fruit; Humans; Methionine; Middle Aged; Odds Ratio; Risk Factors; Surveys and Questionnaires; Vegetables; Women's Health

1998
A new radiocolloid for sentinel node detection in breast cancer.
    Annals of surgical oncology, 2001, Volume: 8, Issue:2

    Topics: Animals; Axilla; Breast Neoplasms; Coloring Agents; Cysteine; Female; Humans; Lymph Nodes; Lymphatic Metastasis; Middle Aged; Neoplasm Staging; Organotechnetium Compounds; Prospective Studies; Rabbits; Radionuclide Imaging; Radiopharmaceuticals; Sensitivity and Specificity; Sentinel Lymph Node Biopsy

2001
Mutation analysis of membrane type-1 matrix metalloproteinase (MT1-MMP). The role of the cytoplasmic tail Cys(574), the active site Glu(240), and furin cleavage motifs in oligomerization, processing, and self-proteolysis of MT1-MMP expressed in breast car
    The Journal of biological chemistry, 2001, Jul-13, Volume: 276, Issue:28

    Topics: Breast Neoplasms; Cysteine; Dimerization; Dipeptides; DNA Mutational Analysis; Enzyme Activation; Female; Fibrosarcoma; Glutamine; Humans; Hydroxamic Acids; Indoles; Matrix Metalloproteinases, Membrane-Associated; Metalloendopeptidases; Mutagenesis, Site-Directed; Protease Inhibitors; Protein Processing, Post-Translational

2001
COMT genotype, micronutrients in the folate metabolic pathway and breast cancer risk.
    Carcinogenesis, 2001, Volume: 22, Issue:10

    Topics: Breast Neoplasms; Case-Control Studies; Catechol O-Methyltransferase; Cysteine; Estrogens, Catechol; Female; Folic Acid; Genotype; Homocysteine; Humans; Methylation; Micronutrients; Middle Aged; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Pyridoxal Phosphate; Risk Factors; S-Adenosylmethionine; Vitamin B 12

2001
Isolation of transcriptionally active chromatin from human breast cancer cells using Sulfolink coupling gel chromatography.
    Journal of cellular biochemistry, 2002, Volume: 84, Issue:3

    Topics: Acetylation; Breast Neoplasms; Chromatin; Chromatography, Gel; Cysteine; DNA, Neoplasm; Estradiol; Female; Histones; Humans; Nucleosomes; Precipitin Tests; Proto-Oncogene Proteins c-myc; Receptors, Estrogen; Sulfhydryl Reagents; Transcription, Genetic; Tumor Cells, Cultured

2002
Copper uptake is required for pyrrolidine dithiocarbamate-mediated oxidation and protein level increase of p53 in cells.
    The Biochemical journal, 2002, Aug-01, Volume: 365, Issue:Pt 3

    Topics: Animals; Antioxidants; Breast Neoplasms; Cells, Cultured; Chelating Agents; Copper; Cysteine; Cysteine Proteinase Inhibitors; Ditiocarb; Female; Fibroblasts; Free Radicals; Humans; Hydrogen Peroxide; Leupeptins; Mannitol; Molecular Structure; Oxidants; Oxidation-Reduction; Pyrrolidines; Rats; Recombinant Proteins; Thiobarbituric Acid Reactive Substances; Thiocarbamates; Tumor Suppressor Protein p53

2002
Conditional derepression of ferritin synthesis in cells expressing a constitutive IRP1 mutant.
    Molecular and cellular biology, 2002, Volume: 22, Issue:13

    Topics: Adaptor Proteins, Signal Transducing; Breast Neoplasms; Carrier Proteins; Cell Cycle Proteins; Cell Division; Cells, Cultured; Cysteine; Female; Ferritins; Gene Expression Regulation; Humans; Iron; Iron Regulatory Protein 1; Iron-Regulatory Proteins; Iron-Sulfur Proteins; Lung Neoplasms; Phosphoproteins; Promoter Regions, Genetic; Protein Biosynthesis; Response Elements; RNA-Binding Proteins; RNA, Messenger; Tetracycline; Tumor Cells, Cultured

2002
5-S-cysteinyldopa in the plasma of melanoma patients and the renal clearance of this amino acid.
    Acta dermato-venereologica, 1975, Volume: 55, Issue:1

    Topics: Adult; Breast Neoplasms; Cysteine; Dihydroxyphenylalanine; Humans; Liver Neoplasms; Lung Neoplasms; Male; Melanoma; Neoplasm Metastasis; Skin Neoplasms

1975
Effect of selenium compounds and thiols on human mammary tumor cells.
    Biological trace element research, 1991, Volume: 30, Issue:2

    Topics: Aged; Antimetabolites; Breast Neoplasms; Buthionine Sulfoximine; Cell Survival; Cysteine; Female; Glutathione; Glutathione Peroxidase; Humans; Mercaptoethanol; Methionine Sulfoximine; Organoselenium Compounds; Selenic Acid; Selenious Acid; Selenium; Selenium Compounds; Selenocysteine; Selenomethionine; Sodium Selenite; Sulfhydryl Compounds; Trypan Blue; Tumor Cells, Cultured

1991
The presence of c-erbB-2 gene product-related protein in culture medium conditioned by breast cancer cell line SK-BR-3.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1990, Volume: 1, Issue:12

    Topics: Animals; Antibodies, Monoclonal; Base Sequence; Blotting, Northern; Breast Neoplasms; Culture Media; Cysteine; Humans; Immunization; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Phosphoproteins; Phosphorus Radioisotopes; Proto-Oncogene Proteins; Receptor, ErbB-2; Sulfur Radioisotopes; Tumor Cells, Cultured

1990
Radiosequence analysis of the human progestin receptor charged with [3H]promegestone. A comparison with the glucocorticoid receptor.
    The Journal of biological chemistry, 1990, Aug-05, Volume: 265, Issue:22

    Topics: Affinity Labels; Amino Acid Sequence; Animals; Binding Sites; Breast Neoplasms; Cell Line; Cysteine; Cytosol; Dexamethasone; Female; Humans; Liver; Methionine; Molecular Sequence Data; Norpregnadienes; Promegestone; Rats; Receptors, Glucocorticoid; Receptors, Progesterone; Sequence Homology, Nucleic Acid; Triamcinolone Acetonide; Tritium

1990
Quantitative determination of water- and lipid-soluble antioxidants in neoplastic and non-neoplastic human breast tissue.
    International journal of cancer, 1989, Jun-15, Volume: 43, Issue:6

    Topics: Antioxidants; Ascorbic Acid; Breast; Breast Neoplasms; Cholesterol; Chromatography, High Pressure Liquid; Cysteine; DNA; DNA, Neoplasm; Epithelium; Female; Glutathione; Humans; Solubility; Uric Acid; Vitamin E

1989
Clinical experience with the testing of serum proteinase activity by cathepsin B-like sensitive amino acid derivatives of 7-amino-4-methylcoumarine.
    Neoplasma, 1987, Volume: 34, Issue:5

    Topics: Adult; Breast Neoplasms; Cathepsin B; Colonic Neoplasms; Coumarins; Cysteine; Edetic Acid; Female; Humans; Hydrogen-Ion Concentration; Hydrolysis; Indicators and Reagents; Male; Middle Aged; Neoplasm Staging; Peptide Hydrolases; Protease Inhibitors; Rectal Neoplasms

1987
[Primary structure of human protein pS2].
    Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie, 1988, Volume: 307, Issue:19

    Topics: Alkylation; Amino Acid Sequence; Base Sequence; Breast Neoplasms; Chromatography, High Pressure Liquid; Culture Media; Cysteine; Gastric Mucosa; Humans; Molecular Sequence Data; Neoplasm Proteins; Oxidation-Reduction; Peptide Fragments; Proteins; RNA, Messenger; Trefoil Factor-1; Trypsin; Tumor Cells, Cultured; Tumor Suppressor Proteins

1988
Quantitative determination of water-soluble scavengers in neoplastic and non-neoplastic human breast tissue.
    International journal of cancer, 1988, May-15, Volume: 41, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Ascorbic Acid; Breast; Breast Neoplasms; Chromatography, High Pressure Liquid; Cysteine; DNA; Epithelium; Extracellular Space; Female; Glutathione; Humans; Middle Aged; Uric Acid

1988
Antiestrogen stimulation of the production of a 37,000 molecular weight secreted protein and estrogen stimulation of the production of a 32,000 molecular weight secreted protein in MCF-7 human breast cancer cells.
    Endocrinology, 1987, Volume: 120, Issue:3

    Topics: Amino Acids; Breast Neoplasms; Cell Line; Cysteine; Estradiol; Female; Humans; Kinetics; Methionine; Molecular Weight; Neoplasm Proteins; Sulfur Radioisotopes; Tamoxifen

1987
The effect of thiols on oestradiol binding by components of human malignant breast tumours.
    The Biochemical journal, 1972, Volume: 130, Issue:1

    Topics: Binding Sites; Breast Neoplasms; Cysteine; Dithiothreitol; Estradiol; Female; Humans; Mercaptoethanol; Sulfhydryl Compounds

1972
[Sulfur-containing compounds of malignant human breast tumors].
    Ukrains'kyi biokhimichnyi zhurnal, 1969, Volume: 41, Issue:1

    Topics: Adenofibroma; Breast Neoplasms; Cysteine; Female; Glutathione; Humans; Sulfur; Tissue Extracts

1969