cysteine and Aging

cysteine has been researched along with Aging in 219 studies

Research

Studies (219)

TimeframeStudies, this research(%)All Research%
pre-199049 (22.37)18.7374
1990's38 (17.35)18.2507
2000's70 (31.96)29.6817
2010's50 (22.83)24.3611
2020's12 (5.48)2.80

Authors

AuthorsStudies
Garg, G; Rizvi, SI; Singh, AK; Singh, S; Verma, AK1
Hine, C; Sharew, B; Yang, J1
Chang, CH; Chen, PH; Ho, CT; Lin, WS; Nagabhushanam, K; Pan, MH1
Katsuta, N; Nagai, M; Nagai, R; Sugawa, H; Takahashi, H1
Ghanemi, A; St-Amand, J; Yoshioka, M1
Cheng, ML; Hsu, WC; Lin, G; Lin, HT; Liu, FC; Lo, CJ1
Bórquez, DA; Urrutia, PJ1
Adhikari, B; Benhar, M; Bursac, B; Carroll, KS; Filipovic, MR; Gomes, JE; Gonzalez-Zorn, B; Ivanovic-Burmazovic, I; Jung, Y; Kohl, JB; Kouroussis, E; Miler, M; Miljkovic, JL; Milosevic, V; Mitchell, JR; Mitchell, S; Paul, BD; Petrovic, D; Schott-Roux, S; Schwarz, G; Snyder, SH; Thomas-Lopez, D; Torregrossa, R; Whiteman, M; Zivanovic, J1
Chouchani, ET; Du, G; Garrity, R; Gray, NS; Gygi, SP; He, Z; Heppner, DE; Huttlin, EL; Jedrychowski, MP; Li, J; Long, J; Mills, EL; Paulo, JA; Reddy, A; Schweppe, DK; Szpyt, J; Vaites, LP; Xiao, H; Yu, Q; Zhang, T1
Cochemé, HM; Lennicke, C1
Akao, Y; Hashimoto, M; Masutani, T; Nakai, T; Unno, K1
Papanikolopoulou, K; Prifti, E; Samiotaki, M; Stamatakis, G; Tsakiri, EN; Vourkou, E1
Quintanar, L; Serebryany, E; Thorn, DC1
Bahrani, S; Ghaedi, M; Javadian, H; Mansoorkhani, MJK; Ostovan, A; Taghipour, T1
Ferreira, LF; Kelley, RC; McDonagh, B1
Goljanek-Whysall, K; Jackson, MJ; McDonagh, B; Smith, NT; Soriano-Arroquia, A1
Akbergenov, R; Böttger, EC; Boukari, H; Duscha, S; Eckert, A; Frank, S; Freihofer, P; Fritz, AK; Isnard-Petit, P; Juskeviciene, R; Oettinghaus, B; Oishi, N; Rehrauer, H; Schacht, J; Schmitt, K; Shcherbakov, D; Teo, Y; Thiam, K; Westhof, E; Wolfer, D1
Brewer, GJ; Digman, MA; Dong, Y; Sameni, S1
Kumar, P; Maurya, PK1
Gonzalez, EV; Nguyen, D; Reddy, VT; Samson, SL; Sekhar, RV1
Béchereau, F; Breuillé, D; Denis, P; Glomot, F; Papet, I; Serrant, P; Vidal, K1
Brewer, GJ; Ghosh, D1
Kumar, D; Rizvi, SI1
Brownridge, P; Jackson, MJ; McDonagh, B; Sakellariou, GK; Smith, NT1
Lee, TH; Yang, HY1
Carotenuto, R; Scudiero, R; Tussellino, M1
Jayasena, DD; Jo, C; Jung, S; Kim, HJ; Nam, KC; Yong, HI1
Chouchani, ET; Cochemé, HM; Ding, S; Fearnley, IM; Harbour, ME; James, AM; Menger, KE; Murphy, MP; Partridge, L1
DiNicolantonio, JJ; McCarty, MF1
Fan, X; Guo, M; Hom, G; Li, B; Monnier, VM; Vaysburg, D; Wang, B; Yang, J; Zhou, S1
Denzer, I; Friedland, K; Münch, G; Pischetsrieder, M1
Bachschmid, MM; Behring, JB; Cohen, RA; Colucci, WS; Costello, CE; Elezaby, A; Matsui, R; McComb, ME; Seta, F; Shao, D; Siwik, DA; Sverdlov, AL; Whelan, SA; Yao, C; Yin, X1
Martínez-Banaclocha, M1
Jackson, MJ; McArdle, A; McDonagh, B; Pollock, N; Scullion, SM; Vasilaki, A1
Blackwell, TK; Hirata, D; Kodera, Y; Mizunuma, M; Ogawa, T1
Buffenstein, R; Gibney, PA; Lewis, KN; McIsaac, RS1
Cabiscol, E; Reverter-Branchat, G; Rodríguez-Colman, MJ; Vall-Llaura, N; Vived, C; Weertman, N1
Ren, X; Sun, Y; Xiong, Y; Zhang, N; Zhang, Y; Zhao, Y; Zhou, S1
Burke, TJ; Ritzenthaler, JD; Roman, J; Torres-González, E; Watson, WH; Zelko, IN1
Gu, L; Robinson, RA1
Fan, X; Guo, M; Hom, G; Li, B; Monnier, VM; Wang, B; Yang, J; Zhou, S1
Aoki, Y; Era, S; Hasegawa, H; Hashimoto, T; Matsuyama, Y; Shinohara, Y; Soejima, A; Suzuki, Y1
Maurya, PK; Rizvi, SI1
Dalle-Donne, I; Giustarini, D; Milzani, A; Rossi, R1
Hains, PG; Truscott, RJ1
Moyer, KL; Trepanier, LA1
Calvani, M; Cantatore, P; Capelli, V; Gadaleta, MN; Mosconi, L; Musicco, C; Pesce, V; Timperio, AM; Zolla, L1
Glover, CN; Hogstrand, C; Jayashankar, S; Lundebye, AK; Sales, GD; Zheng, D1
Buendia, B; Dabauvalle, MC; Kandert, S; Müller, CR; Wehnert, M1
Agosti, C; Alberici, A; Bellelli, G; Borroni, B; Garibotto, V; Giubbini, R; Lucchini, S; Padovani, A; Paghera, B; Perani, D; Premi, E1
Guttmann, RP1
Büyüknacar, HS; de Groat, WC; Göçmen, C; Kumcu, EK; Onder, S; Wu, HY1
Oettl, K; Reibnegger, G; Schmut, O1
Ago, T; Fu, C; Kuroda, J; Li, H; Pain, J; Sadoshima, J1
Bossy, B; Bossy-Wetzel, E; Chen, J; Klinglmayr, E; Knott, AB; Lütz-Meindl, U; Masliah, E; Petrilli, A; Schwarzenbacher, R1
Herrmann, JM; Riemer, J1
Hirota, M; Morisawa, H; Nakamura, M; Nishigaki, R; Toda, T; Yoshimi, Y1
Andley, UP; Reilly, MA1
Heman-Ackah, SE; Huang, TC; Juhn, SK; Wiedmann, TS1
Kang, R; Lotze, MT; Tang, D; Zeh, HJ1
Dou, DQ; Gao, MB; Li, CB; Li, HC; Li, XT1
Apeland, T; Bates, CJ; Drabløs, PA; Hervig, T; Mansoor, MA; Stakkestad, JA; Wentzel-Larsen, T1
Behl, C; Moosmann, B; Schindeldecker, M; Stark, M1
Ma, J; Wang, N; Wang, Y; Yu, G; Yuan, C1
Balasubramanyam, A; Guthikonda, AP; Jahoor, F; Patel, SG; Reid, M; Sekhar, RV; Taffet, GE1
David, LL; Davies, MJ; Friedrich, MG; Hooi, MY; Jamie, JF; Lyons, B; Mizdrak, J; Truscott, RJ; Wilmarth, PA1
Black, SE; MacIntosh, BJ; Makedonov, I1
Fujii, N; Kita, A; Miki, K; Shimizu, K1
Gladyshev, VN; Labunskyy, VM1
Apostolova, I; Brenner, W; Buchert, R; Derlin, T; Dirnagl, U; Goldschmidt, J; Gregor-Mamoudou, B; Lukas, M; Michel, R; Stemmer, N; Wunder, A1
Attia, JR; Carru, C; Mangoni, AA; McEvoy, M; Zinellu, A1
Liu, RM1
Eto, K; Kimura, H1
Smoleński, O; Sokołowska, M; Włodek, L; Włodek, P1
Carlson, JL; Jones, DP; Lynn, MJ; Mody, VC; Sternberg, P1
Adroher, FJ; Benítez, R; Gálvez, L; Iglesias, L; Valero, A1
Lapko, VN; Smith, DL; Smith, JB1
Audenaert, K; Blanckaert, P; Coopman, F; Dierckx, R; Jacobs, F; Mertens, J; Peremans, K; Slegers, G; Van Bree, H; Van Heeringen, C; Verschooten, F1
Asada, T; Imabayashi, E; Kanetaka, H; Li, ZJ; Matsuda, H; Nakano, S; Ohnishi, T; Tanaka, F1
Blom, HJ; Bosma, H; Bosmans, E; De Bruijn, C; de Vente, J; Delanghe, J; Lütjohann, D; Maes, M; Rieckmann, P; Steinbusch, HW; Teunissen, CE; van Boxtel, MP; Verbeek, MM; Verhey, F; von Bergmann, K; Vreeling, F; Wauters, A1
OERIU, S; PARHON, CI1
THOMANN, H1
OERIU, S3
COSTESCU, G; OERIU, S; TEODORESCU, O1
OERIU, S; TANASE, I5
OERIU, S; VERZAR, F1
OERIU, S; TIGHECIU, M3
GRIGORESCO, G; MANESCO, M; MARZA, E; OERIU, S; SOIMU, I; TANASESCO, G1
BENESCH, H; CRACEA, M; OERIU, S1
Fukuda, H; Goto, R; Inoue, K; Kinomura, S; Nakagawa, M; Sato, K; Sato, T1
Kim, SY; Kim, YC; Sohn, YR1
Craghill, J; Cronshaw, AD; Harding, JJ1
Hagen, TM; Liu, J; Liu, RM; Suh, JH; Wang, H1
Breuillé, D; Buffière, C; Mirand, PP; Mosoni, L; Obled, C1
Asada, T; Imabayashi, E; Kanetaka, H; Li, ZJ; Matsuda, H; Ohnishi, T; Tanaka, F1
Bald, E; Chwatko, G; Iciek, M; Lorenc-Koci, E; Włodek, L1
Adman, ET; Kamath-Loeb, AS; Loeb, LA; Waite, M; Welcsh, P1
Kil, IS; Lee, JH; Park, JW; Shin, AH1
Buonocore, G; Capecchi, PL; Cellesi, C; Di Giuseppe, D; Di Simplicio, FC; Di Simplicio, P; Frosali, S; Jakubowski, H; Lazzerini, PE; Pasini, FL; Priora, R1
Sohal, RS; Toroser, D2
Pulliam, L; Rempel, HC1
Carageorgiou, H; Schulpis, KH; Tsakiris, S1
Bardsley, V; Fellows, IW; Jennings, BA; Lonsdale, R; Willis, G; Wimperis, JZ1
Prochniewicz, E; Thomas, DD; Thompson, LV1
Packer, L; Paetau-Robinson, I; Rebrin, I; Sohal, RS; Wedekind, KJ; Zicker, S1
Dremina, ES; Galeva, NA; Schöneich, C; Sharov, VS; Williams, TD1
Aoyama, K; Chan, WY; Chen, Y; Hamby, AM; Liu, J; Suh, SW; Swanson, RA1
Dröge, W2
Davis, SR; Gregory, JF; Quinlivan, EP; Stacpoole, PW1
Breuillé, D; Buffière, C; Gimonet, J; Mercier, S; Mirand, PP; Obled, C; Papet, I1
Jones, DP1
Higuchi, O; Nishimura, H; Nomura, Y; Okuma, Y; Tateshita, K; Tomobe, K1
Browndyke, J; Ghio, A; Schmechel, DE1
Bonini, NM; Ischiropoulos, H; Meulener, MC; Thompson, L; Thomson, L; Xu, K1
Dalle-Donne, I; Giustarini, D; Lorenzini, S; Milzani, A; Rossi, R1
Chaudhuri, AR; De Waal, E; Goins, BA; Grubbs, B; Herman, B; Ikeno, Y; Mundy, GR; Padalecki, SS; Richardson, A; Zhang, Y1
Csete, M; Hansen, JM; Harris, C; Klass, M1
Ahmad, MS; Ahmed, N; Pischetsrieder, M1
Babinet, C; Cohen-Tannoudji, M; Domenga, V; Gridley, T; Joutel, A; Langa, F; Lemaire, B; Monet, M; Souilhol, C; Tournier-Lasserve, E1
Gladyshev, VN; Koc, A1
Davies, MJ; Jamie, JF; Korlimbinis, A; Parker, NR; Truscott, RJ1
Andres-Mateos, E; Blanchard-Fillion, B; Dawson, TM; Dawson, VL; Greco, TM; Ischiropoulos, H; Ko, HS; Perier, C; Przedborski, S; Sasaki, M; Thomas, B; Zhang, L1
Accardi, CJ; Blanco, RA; Carlson, BA; Cheng, PY; Cotsonis, GA; Jones, DP; Park, Y; Ziegler, TR1
Behl, C; Moosmann, B1
Kobayashi, A; Maher, J; Motohashi, H; Suzuki, T; Wakabayashi, J; Yamamoto, M; Yamamoto, T1
Higashi, T; Nakashima, K; Sakamoto, Y; Tateishi, N1
Mal'tsev, EV1
Crane, IJ; Hunt, DM1
Garner, MH; Spector, A1
Misra, CH1
Fujii, O; Hosokawa, Y; Kohashi, N; Kori, Y; Ueda, I; Yamaguchi, K1
Noguchi, T; Tanaka, T; Yamamoto, N1
Alt, FW; Baldassare, M; Fisher, P; Jessell, TM; Oltz, EM; Rathbun, G; Xu, Y; Yancopoulos, GD1
Camerino, DC; Tricarico, D1
Conte Camerino, D; Mallamaci, R; Tricarico, D; Wagner, R1
Burne, JF; Ishizaki, Y; Raff, MC1
Hamazaki, S; Minamiyama, Y; Okada, S; Sotomatsu, A; Toyokuni, S1
Arola, LI; Salvadó, MJ1
Richie, JP; Vogt, BL1
Cousins, RJ; Lee-Ambrose, LM; Levenson, CW; Shay, NF1
Dickerson, JE; Lou, MF1
Cui, XL; Lou, MF; Xu, GT1
Qin, C; Rao, PV; Russell, P; Tumminia, SJ; Zigler, JS1
Allen, RG; Cristofalo, VJ; Keogh, BP; Tresini, M1
Fung, YW; Liew, CC; Wang, R1
Kawase, M; Kinoshita, C; Murata, H; Nakata, K; Ogata, K; Ogino, S; Ohmori, S; Sakaue, T1
Takemoto, L1
Beneduce, F; Delle Cave, M; Loguercio, C; Taranto, D; Vitale, LM1
Abe, M; Funaba, M; Iriki, T1
Barthel, H; Dannenberg, C; Knapp, WH; Martin, WG; Sattler, B; Wiener, M1
Douglas, MW; Johnson, ML; Parsons, CM1
Daitoh, N; Hara, S; Kawahata, N; Shirai, F1
Linetsky, M; Ortwerth, BJ; Ranson, N1
Bottje, WG; Cawthon, D; Wang, S1
Hendriks, WH; Moughan, PJ; Tarttelin, MF1
Berglund, L; Berne, C; Brattström, L; Refsum, H; Ueland, PM; Wollesen, F1
Bigelow, DJ; Ferrington, DA; Schöneich, C; Viner, RI; Williams, TD1
Aranda, JV; Bardin, CL; Hoffer, LJ; Hongsprabhas, P; Kovacs, LB; Papageorgiou, AN; Saboohi, F1
Abraham, EC; Cherian-Shaw, M; Jiang, XY; Smith, JB1
Ikeda, E; Kuji, I; Niida, Y; Sumiya, H; Takizawa, N; Tonami, N; Tsuji, S1
Arnalich, F; Fernández-Vivancos, E; Hernanz, A; Salazar, RM1
Kaminski, HJ; Richmonds, CR1
Asada, T; Matsuda, H; Nakano, S; Takasaki, M; Uno, M1
Kala, G; Kala, SV; Lieberman, MW; Rojas, E; Valverde, M1
Chen, TS; Lang, CA; Nagasawa, HT; Richie, JP1
Brown, G; Castro, E; Deeb, SS; Edland, SD; Erkkola, R; Lee, L; Louhija, J; Martin, GM; Ogburn, CE; Oshima, J; Panduro, A; Penttinen, R; Riestra, R; Tilvis, R; Wang, L1
Moriguchi, T; Morihara, N; Nishiyama, N; Saito, H1
Dierckx, R; Dumont, F; Koole, M; Van Laere, K1
Achten, E; Audenaert, K; Dierckx, R; Goethals, I; Koole, M; Van Laere, K; Versijpt, J1
Mallis, RJ; Thomas, JA1
Bishopric, NH; Prentice, H; Webster, KA1
Dierckx, RA; Van Laere, KJ1
Stadtman, ER1
Bates, CJ; Gregory, J; Mansoor, MA; Pentiev, K; Prentice, A1
Di Giorgio, RM; Macaione, S; Tucci, G1
Kent, S1
Ali, SY; Bayliss, MT1
Miyahara, T; Murai, A; Shiozawa, S1
Baines, PJ; Bray, HG; James, SP1
Dabrowska, BK; Dabrowski, MP; Ryzewski, J1
Martin, WG; Porter, DW1
Bando, M; Obazawa, H; Sueno, T1
Daniels, CK; Gregoire, CD; Zhang, L1
Chen, TS; Lang, CA; Richie, JP2
Darnerud, PO; Feil, VJ; Gustafson, AL; Törnwall, U1
Murray, DL; Rathbun, WB1
Gafni, A; Zhou, JQ1
Arkins, S; Franklin, RA; Kelley, KW; Li, YM1
Dickerson, JE; Garadi, R; Lou, MF1
Klaude, M; von der Decken, A3
Cook, LL; Gafni, A1
Lang, CA; Richie, JP1
Calvin, HI; Cohen, G; Slivka, A; Spina, MB1
Akagi, R; Akahori, S; Ejiri, K; Kanemori, H; Kudo, T; Sekiba, K; Ubuka, T1
Harding, JJ1
Garweg, G; Kinsky, I1
Bruno, R; Rinaudo, MT1
Moser, P; Verzár, F1
Hubbard, R; Sperling, L1
Demerec, M; Gillespie, D; Itikawa, H1
Bruhis, S; Dumitraşc, N; Klein, R; Moldoveanu, E; Oeriu, S1
Dobre, V; Oeriu, S; Winter, D1
Finkelstein, JD; Harris, BJ; Kyle, W1
Segal, S; Smith, I1
Tanase, I1
Adam, A; Colombo, JP; Richterich, R; Wiesmann, U1

Reviews

19 review(s) available for cysteine and Aging

ArticleYear
Redox signalling and ageing: insights from Drosophila.
    Biochemical Society transactions, 2020, 04-29, Volume: 48, Issue:2

    Topics: Aging; Animals; Antioxidants; Cell Death; Cysteine; Drosophila; Humans; Longevity; Mitochondria; Oxidation-Reduction; Oxidative Stress; Oxygen; Reactive Oxygen Species; Signal Transduction

2020
Redox chemistry of lens crystallins: A system of cysteines.
    Experimental eye research, 2021, Volume: 211

    Topics: Aging; Cysteine; Disulfides; gamma-Crystallins; Glutathione; Glutathione Disulfide; Humans; Lens, Crystalline; Oxidation-Reduction; Sulfhydryl Compounds

2021
Antioxidant enzymes as redox-based biomarkers: a brief review.
    BMB reports, 2015, Volume: 48, Issue:4

    Topics: Aging; Alzheimer Disease; Animals; Antioxidants; Biomarkers; Catalysis; Cell Line, Tumor; Cysteine; Enzymes; Glutathione; Hep G2 Cells; Humans; Hypertension, Renal; Neurodegenerative Diseases; Oxidation-Reduction; Oxidative Stress; Oxygen; Peroxiredoxins; Protein Processing, Post-Translational; Proteomics; Reactive Oxygen Species; Reperfusion Injury

2015
An increased need for dietary cysteine in support of glutathione synthesis may underlie the increased risk for mortality associated with low protein intake in the elderly.
    Age (Dordrecht, Netherlands), 2015, Volume: 37, Issue:5

    Topics: Aged; Aging; Cysteine; Diet, Protein-Restricted; Dietary Supplements; Global Health; Glutathione; Humans; Nutrition Surveys; Risk Factors; Survival Rate

2015
Cysteine Network (CYSTEINET) Dysregulation in Parkinson's Disease: Role of N-acetylcysteine.
    Current drug metabolism, 2016, Volume: 17, Issue:4

    Topics: Acetylcysteine; Aging; Amino Acid Transport System y+; Brain; Cysteine; Energy Metabolism; Glutathione; Homeostasis; Humans; Metabolic Networks and Pathways; Oxidation-Reduction; Parkinson Disease; Protein Processing, Post-Translational; Reactive Oxygen Species

2016
From yeast to human: exploring the comparative biology of methionine restriction in extending eukaryotic life span.
    Annals of the New York Academy of Sciences, 2016, Volume: 1363

    Topics: Aging; Animals; Caloric Restriction; Cysteine; Eukaryotic Cells; Humans; Invertebrates; Life Expectancy; Longevity; Metabolic Networks and Pathways; Methionine; Models, Animal; Rodentia; Yeasts

2016
Proteomic approaches to quantify cysteine reversible modifications in aging and neurodegenerative diseases.
    Proteomics. Clinical applications, 2016, Volume: 10, Issue:12

    Topics: Aging; Animals; Cysteine; Humans; Neurodegenerative Diseases; Oxidation-Reduction; Protein Processing, Post-Translational; Proteomics

2016
Redox regulation of cysteine-dependent enzymes.
    Journal of animal science, 2010, Volume: 88, Issue:4

    Topics: Aging; Animal Nutritional Physiological Phenomena; Animals; Antioxidants; Cell Physiological Phenomena; Cells; Cysteine; Homeostasis; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Transcription, Genetic

2010
Proteomic approaches to oxidative protein modifications implicated in the mechanism of aging.
    Geriatrics & gerontology international, 2010, Volume: 10 Suppl 1

    Topics: Aging; Alzheimer Disease; Animals; Cysteine; Electrophoresis, Gel, Two-Dimensional; Humans; Isoelectric Focusing; Methionine; Oxidative Stress; Protein Biosynthesis; Protein Carbonylation; Proteomics; Reactive Oxygen Species

2010
High-mobility group box 1, oxidative stress, and disease.
    Antioxidants & redox signaling, 2011, Apr-01, Volume: 14, Issue:7

    Topics: Aging; Animals; Antioxidants; Atherosclerosis; Cell Death; Cysteine; DNA Damage; DNA Repair; HMGB1 Protein; HSP72 Heat-Shock Proteins; Humans; Oxidation-Reduction; Oxidative Stress; Protein Structure, Tertiary; Protein Transport; Reactive Oxygen Species; Reperfusion Injury; Signal Transduction; Toll-Like Receptor 4

2011
Role of reactive oxygen species-mediated signaling in aging.
    Antioxidants & redox signaling, 2013, Oct-20, Volume: 19, Issue:12

    Topics: Aging; Animals; Cysteine; Humans; Longevity; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Signal Transduction

2013
Oxidative stress and ageing: is ageing a cysteine deficiency syndrome?
    Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2005, Dec-29, Volume: 360, Issue:1464

    Topics: Aging; Body Composition; Cysteine; Dietary Supplements; Glutathione; Humans; Immunity, Cellular; Muscle, Skeletal; Oxidative Stress; Protein Tyrosine Phosphatases; Reactive Oxygen Species; Receptor, Insulin; Serum Albumin; Signal Transduction; Tumor Necrosis Factor-alpha

2005
Oxidative aging and insulin receptor signaling.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2005, Volume: 60, Issue:11

    Topics: Adiposity; Aging; Animals; Body Composition; Caloric Restriction; Cysteine; Dietary Supplements; Humans; Oxidative Stress; Receptor, Insulin; Signal Transduction; Tumor Necrosis Factor-alpha

2005
Extracellular redox state: refining the definition of oxidative stress in aging.
    Rejuvenation research, 2006,Summer, Volume: 9, Issue:2

    Topics: Aging; Cell Proliferation; Cysteine; Glutathione; Health Status; Humans; Macular Degeneration; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Signal Transduction; Smoking; Thioredoxins

2006
[Conservative treatment of cataract].
    Oftalmologicheskii zhurnal, 1984, Issue:7

    Topics: Acridines; Aged; Aging; Cataract; Crystallins; Cysteine; Drug Therapy, Combination; Humans; Hypercholesterolemia; Hyperglycemia; Iontophoresis; Lens, Crystalline; Methylthiouracil; Middle Aged; Ophthalmic Solutions; Procaine; Protein Denaturation; Tiopronin; Vitamins

1984
Aging and oxidation of reactive protein sulfhydryls.
    Experimental gerontology, 2001, Volume: 36, Issue:9

    Topics: Aging; Animals; Cysteine; Glutathione; Humans; Oxidation-Reduction; Oxidative Stress; Proteins; Reactive Oxygen Species; Sulfhydryl Compounds

2001
Oxidation of zinc finger transcription factors: physiological consequences.
    Antioxidants & redox signaling, 2001, Volume: 3, Issue:4

    Topics: Aging; Animals; Antioxidants; Binding Sites; Breast Neoplasms; Chlorocebus aethiops; COS Cells; Cysteine; DNA; DNA-Binding Proteins; Early Growth Response Protein 1; Escherichia coli Proteins; Female; Gene Expression Regulation; HeLa Cells; Humans; Immediate-Early Proteins; Models, Biological; Neoplasm Proteins; Oxidation-Reduction; Oxidative Stress; Oxidoreductases; Protein Binding; Protein Conformation; Receptors, Estrogen; Receptors, Glucocorticoid; Sp1 Transcription Factor; Structure-Activity Relationship; Sulfhydryl Reagents; Superoxides; Transcription Factors; Zinc Fingers

2001
Protein oxidation in aging and age-related diseases.
    Annals of the New York Academy of Sciences, 2001, Volume: 928

    Topics: Aging; Amino Acids; Animals; Antioxidants; Apoptosis; Cross-Linking Reagents; Cysteine; Disease; Humans; Longevity; Methionine; Models, Biological; Nitric Oxide; Oxidants; Oxidation-Reduction; Oxidative Stress; Peptides; Peroxynitrous Acid; Protein Denaturation; Proteins; Rats; Reactive Oxygen Species; Tyrosine

2001
Do free radicals and dietary antioxidants wage intracellular war?
    Geriatrics, 1977, Volume: 32, Issue:1

    Topics: Aging; Animals; Antioxidants; Ascorbic Acid; Butylated Hydroxytoluene; Catechols; Cysteine; Cystine; Diet; Drug Combinations; Ethoxyquin; Female; Free Radicals; Humans; Life Expectancy; Lipid Metabolism; Male; Mercaptoethylamines; Methionine; Mice; Mice, Inbred Strains; Oxidation-Reduction; Peroxides; Selenium; Superoxide Dismutase; Vitamin E

1977

Trials

6 trial(s) available for cysteine and Aging

ArticleYear
Deficient synthesis of glutathione underlies oxidative stress in aging and can be corrected by dietary cysteine and glycine supplementation.
    The American journal of clinical nutrition, 2011, Volume: 94, Issue:3

    Topics: Adult; Age Factors; Aged; Aging; Cysteine; Dietary Supplements; Erythrocytes; F2-Isoprostanes; Glutathione; Glycine; Humans; Isotopes; Metabolic Diseases; Oxidative Stress; Staining and Labeling

2011
Correction for partial-volume effects on brain perfusion SPECT in healthy men.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2003, Volume: 44, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Algorithms; Artifacts; Brain; Cerebrovascular Circulation; Cysteine; Humans; Image Enhancement; Magnetic Resonance Imaging; Male; Middle Aged; Organotechnetium Compounds; Phantoms, Imaging; Quality Control; Radiopharmaceuticals; Reference Values; Subtraction Technique; Tomography, Emission-Computed, Single-Photon

2003
Combination of serum markers related to several mechanisms in Alzheimer's disease.
    Neurobiology of aging, 2003, Volume: 24, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Aging; alpha 1-Antichymotrypsin; Alzheimer Disease; Analysis of Variance; Biomarkers; Chi-Square Distribution; Cholesterol; Cysteine; Female; Follow-Up Studies; Humans; Hydroxycholesterols; Interleukin-6; Logistic Models; Male; Middle Aged; Neurodegenerative Diseases; Parkinson Disease; Reference Values; Serum; Sterols

2003
Regional differences between 99mTc-ECD and 99mTc-HMPAO SPET in perfusion changes with age and gender in healthy adults.
    European journal of nuclear medicine and molecular imaging, 2003, Volume: 30, Issue:11

    Topics: Age Factors; Aging; Brain; Cerebrovascular Circulation; Cysteine; Female; Humans; Male; Middle Aged; Organotechnetium Compounds; Radiopharmaceuticals; Reference Values; Reproducibility of Results; Sensitivity and Specificity; Sex Factors; Technetium Tc 99m Exametazime; Tomography, Emission-Computed, Single-Photon

2003
Gender difference in brain perfusion 99mTc-ECD SPECT in aged healthy volunteers after correction for partial volume effects.
    Nuclear medicine communications, 2004, Volume: 25, Issue:10

    Topics: Aged; Aged, 80 and over; Aging; Algorithms; Brain; Cerebrovascular Circulation; Cysteine; Female; Humans; Image Enhancement; Image Interpretation, Computer-Assisted; Male; Middle Aged; Organotechnetium Compounds; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Sex Factors; Tomography, Emission-Computed, Single-Photon

2004
Plasma glutathione and cystathionine concentrations are elevated but cysteine flux is unchanged by dietary vitamin B-6 restriction in young men and women.
    The Journal of nutrition, 2006, Volume: 136, Issue:2

    Topics: Adult; Aging; Amino Acids; Cystathionine; Cysteine; Diet; Female; Glutathione; Humans; Male; Peptides; Vitamin B 6

2006

Other Studies

194 other study(ies) available for cysteine and Aging

ArticleYear
Whey protein concentrate protects against age-dependent alteration in redox biomarkers.
    Biologia futura, 2020, Volume: 71, Issue:3

    Topics: Aging; Animals; Biomarkers; Cysteine; Drug Evaluation, Preclinical; Erythrocytes; Glycation End Products, Advanced; Lipid Metabolism; Male; Oxidative Stress; Rats, Wistar; Reactive Oxygen Species; Tryptophan; Tyrosine; Whey Proteins

2020
Late-life fasting imparts resiliency and protein persulfidation.
    Aging, 2021, 12-13, Volume: 13, Issue:23

    Topics: Aging; Animals; Cysteine; Fasting; Humans; Protein Processing, Post-Translational; Sulfhydryl Compounds

2021
S-Allylcysteine Ameliorates Aging Features via Regulating Mitochondrial Dynamics in Naturally Aged C57BL/6J Mice.
    Molecular nutrition & food research, 2022, Volume: 66, Issue:7

    Topics: Aging; Animals; Caenorhabditis elegans; Cysteine; Male; Mice; Mice, Inbred C57BL; Mitochondrial Dynamics; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Sirtuin 1

2022
Changes in S-(2-succinyl)cysteine and advanced glycation end-products levels in mouse tissues associated with aging.
    Amino acids, 2022, Volume: 54, Issue:4

    Topics: Aging; Animals; Chromatography, Liquid; Cysteine; Fumarates; Glycation End Products, Advanced; Male; Mice; Mice, Inbred C57BL; Tandem Mass Spectrometry

2022
Genetic Expression between Ageing and Exercise: Secreted Protein Acidic and Rich in Cysteine as a Potential "Exercise Substitute" Antiageing Therapy.
    Genes, 2022, 05-26, Volume: 13, Issue:6

    Topics: Aging; Animals; Cysteine; Exercise; Gene Expression; Humans; Mice; Osteonectin; Physical Conditioning, Animal

2022
Exploring the aging process of cognitively healthy adults by analyzing cerebrospinal fluid metabolomics using liquid chromatography-tandem mass spectrometry.
    BMC geriatrics, 2023, 04-05, Volume: 23, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aging; Asparagine; Chromatography, Liquid; Cognition; Cohort Studies; Cysteine; Fasting; Female; Healthy Volunteers; Humans; Hydroxyindoleacetic Acid; Male; Metabolome; Middle Aged; Pantothenic Acid; Tandem Mass Spectrometry; Young Adult

2023
Expanded bioinformatic analysis of Oximouse dataset reveals key putative processes involved in brain aging and cognitive decline.
    Free radical biology & medicine, 2023, Volume: 207

    Topics: Aging; Animals; Brain; Cognitive Dysfunction; Cysteine; Mice; Oxidation-Reduction; Oxidative Stress; Proteins; Proteomics; Reactive Oxygen Species

2023
Selective Persulfide Detection Reveals Evolutionarily Conserved Antiaging Effects of S-Sulfhydration.
    Cell metabolism, 2019, 12-03, Volume: 30, Issue:6

    Topics: Aging; Animals; Caenorhabditis elegans; Cell Line; Cyclohexanones; Cysteine; Drosophila melanogaster; Escherichia coli; Fibroblasts; Humans; Hydrogen Sulfide; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Protein Processing, Post-Translational; Rats; Rats, Wistar; Saccharomyces cerevisiae; Staining and Labeling; Sulfides

2019
A Quantitative Tissue-Specific Landscape of Protein Redox Regulation during Aging.
    Cell, 2020, 03-05, Volume: 180, Issue:5

    Topics: Aging; Animals; Cysteine; Humans; Mice; Organ Specificity; Oxidation-Reduction; Oxidative Stress; Proteins; Proteome; Proteomics; Reactive Oxygen Species; Signal Transduction

2020
Improvement of Learning and Memory in Senescence-Accelerated Mice by S-Allylcysteine in Mature Garlic Extract.
    Nutrients, 2020, Jun-19, Volume: 12, Issue:6

    Topics: Aging; Animals; Cells, Cultured; Cognitive Dysfunction; Cysteine; Disease Models, Animal; Garlic; Hippocampus; Male; Maze Learning; Memory; Mice; Mice, Inbred C57BL; Plant Extracts

2020
The Two Cysteines of Tau Protein Are Functionally Distinct and Contribute Differentially to Its Pathogenicity
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021, 01-27, Volume: 41, Issue:4

    Topics: Aging; Alanine; Amino Acid Substitution; Animals; Animals, Genetically Modified; Behavior, Animal; Cysteine; Drosophila; Epitopes; Female; Humans; Male; Microtubules; Mutation; Phosphorylation; tau Proteins; Tauopathies

2021
A facile and selective approach for enrichment of l-cysteine in human plasma sample based on zinc organic polymer: Optimization by response surface methodology.
    Journal of pharmaceutical and biomedical analysis, 2018, Feb-05, Volume: 149

    Topics: Adsorption; Aging; Analysis of Variance; Chromatography, High Pressure Liquid; Cysteine; Feasibility Studies; Humans; Limit of Detection; Metal-Organic Frameworks; Microscopy, Electron, Scanning; Powder Diffraction; Solid Phase Microextraction; Spectroscopy, Fourier Transform Infrared; Surface Properties; Ultrasonic Waves; X-Ray Diffraction; Zinc

2018
Advanced aging causes diaphragm functional abnormalities, global proteome remodeling, and loss of mitochondrial cysteine redox flexibility in mice.
    Experimental gerontology, 2018, Volume: 103

    Topics: Aging; Animals; Cysteine; Diaphragm; Male; Mice; Mice, Inbred C57BL; Mitochondria; Mitochondrial Proteins; Oxidation-Reduction; Physical Conditioning, Animal; Proteome; Proteomics

2018
Redox responses are preserved across muscle fibres with differential susceptibility to aging.
    Journal of proteomics, 2018, 04-15, Volume: 177

    Topics: Aging; Animals; Cysteine; Mice; Muscle Fibers, Skeletal; Muscle, Skeletal; Oxidation-Reduction; Proteome; Proteomics; Quadriceps Muscle; Reactive Oxygen Species

2018
Mutant MRPS5 affects mitoribosomal accuracy and confers stress-related behavioral alterations.
    EMBO reports, 2018, Volume: 19, Issue:11

    Topics: Aging; Animals; Behavior, Animal; Brain; Cysteine; Electron Transport Complex IV; Escherichia coli Proteins; Hearing Disorders; HEK293 Cells; Humans; Methionine; Mice, Transgenic; Mitochondria; Mitochondrial Proteins; Noise; Protein Biosynthesis; Ribosomal Proteins; Ribosomes; RNA, Messenger; Stress, Physiological

2018
Reversibility of Age-related Oxidized Free NADH Redox States in Alzheimer's Disease Neurons by Imposed External Cys/CySS Redox Shifts.
    Scientific reports, 2019, 08-02, Volume: 9, Issue:1

    Topics: Aging; Alzheimer Disease; Animals; Cell Nucleus; Cells, Cultured; Cellular Senescence; Cysteine; Cystine; Cytoplasm; Disease Models, Animal; Energy Metabolism; Female; Hippocampus; Humans; Intravital Microscopy; Male; Mice; Mice, Transgenic; Microscopy, Fluorescence; Mitochondria; NAD; Neurons; Oxidation-Reduction; Oxidative Stress; Primary Cell Culture

2019
L-cysteine efflux in erythrocytes as a function of human age: correlation with reduced glutathione and total anti-oxidant potential.
    Rejuvenation research, 2013, Volume: 16, Issue:3

    Topics: Adult; Aged; Aging; Antioxidants; Cysteine; Erythrocytes; Glutathione; Humans; Middle Aged; Young Adult

2013
Impaired mitochondrial fatty acid oxidation and insulin resistance in aging: novel protective role of glutathione.
    Aging cell, 2013, Volume: 12, Issue:3

    Topics: Aging; Animals; Antioxidants; Body Composition; Cholesterol, LDL; Cholesterol, VLDL; Cysteine; Fatty Acids; Glucose; Glutathione; Glycine; Humans; Insulin Resistance; Lipid Metabolism; Male; Mice; Mice, Inbred C57BL; Mitochondria; Muscle, Skeletal; Oxidation-Reduction; Oxidative Stress; Palmitates

2013
Long-term cysteine fortification impacts cysteine/glutathione homeostasis and food intake in ageing rats.
    European journal of nutrition, 2014, Volume: 53, Issue:3

    Topics: Aging; Animals; Anorexia; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Appetite Regulation; Cysteine; Dietary Supplements; Energy Intake; Enteritis; Glutathione; Hepatitis; Homeostasis; Inflammation Mediators; Intestinal Mucosa; Intestine, Small; Liver; Male; Oxidative Stress; Rats, Wistar

2014
External cys/cySS redox state modification controls the intracellular redox state and neurodegeneration via Akt in aging and Alzheimer's disease mouse model neurons.
    Journal of Alzheimer's disease : JAD, 2014, Volume: 42, Issue:1

    Topics: Aging; Alzheimer Disease; Animals; Cell Death; Cells, Cultured; Cysteine; Cystine; Disease Models, Animal; Extracellular Space; Glutathione; Male; Mice; Mice, Transgenic; NADP; Neurons; Oxidation-Reduction; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species

2014
Markers of oxidative stress in senescent erythrocytes obtained from young and old age rats.
    Rejuvenation research, 2014, Volume: 17, Issue:5

    Topics: Acetylcholinesterase; Aging; Animals; Biomarkers; Cell Membrane; Cellular Senescence; Cysteine; Erythrocytes; Glutathione; Male; Malondialdehyde; Oxidation-Reduction; Oxidative Stress; Rats, Wistar; Time Factors

2014
Differential cysteine labeling and global label-free proteomics reveals an altered metabolic state in skeletal muscle aging.
    Journal of proteome research, 2014, Nov-07, Volume: 13, Issue:11

    Topics: Acetylation; Aconitate Hydratase; Aging; Amino Acid Sequence; Animals; Blotting, Western; Cysteine; Endoplasmic Reticulum Chaperone BiP; Fructose-Bisphosphate Aldolase; Male; Mice, Inbred C57BL; Molecular Sequence Data; Muscle Proteins; Muscle, Skeletal; Oxidation-Reduction; Oxidative Stress; Proteomics; Tandem Mass Spectrometry

2014
Identification and expression of an atypical isoform of metallothionein in the African clawed frog Xenopus laevis.
    Comptes rendus biologies, 2015, Volume: 338, Issue:5

    Topics: Aging; Amino Acid Sequence; Animals; Base Sequence; Biological Evolution; Cloning, Molecular; Computational Biology; Cysteine; DNA, Complementary; Gene Expression Regulation; Metallothionein; Molecular Sequence Data; Phylogeny; Protein Isoforms; Real-Time Polymerase Chain Reaction; RNA; Xenopus laevis

2015
Taste-active compound levels in Korean native chicken meat: The effects of bird age and the cooking process.
    Poultry science, 2015, Volume: 94, Issue:8

    Topics: Aging; Animals; Carbohydrates; Chickens; Cooking; Cysteine; Fatty Acids; Glutamic Acid; Inosine Monophosphate; Meat; Republic of Korea; Taste

2015
Fasting, but Not Aging, Dramatically Alters the Redox Status of Cysteine Residues on Proteins in Drosophila melanogaster.
    Cell reports, 2015, Jun-30, Volume: 11, Issue:12

    Topics: Aging; Animals; Cysteine; Drosophila melanogaster; Fasting; Oxidation-Reduction; Oxidative Stress; Protein Biosynthesis; Proteomics; Reactive Oxygen Species

2015
Evidence of Highly Conserved β-Crystallin Disulfidome that Can be Mimicked by In Vitro Oxidation in Age-related Human Cataract and Glutathione Depleted Mouse Lens.
    Molecular & cellular proteomics : MCP, 2015, Volume: 14, Issue:12

    Topics: Aging; Animals; beta-Crystallins; Cataract; Cell Line; Cysteine; Disease Models, Animal; Disulfides; Glutathione; Humans; In Vitro Techniques; Lens, Crystalline; Mice; Oxidation-Reduction; Protein Conformation; Proteomics

2015
S-allyl-L-cysteine and isoliquiritigenin improve mitochondrial function in cellular models of oxidative and nitrosative stress.
    Food chemistry, 2016, Mar-01, Volume: 194

    Topics: Aging; Alzheimer Disease; Animals; Chalcones; Cysteine; Humans; Mitochondria; Oxidation-Reduction; Oxidative Stress; Rats

2016
Overexpression of Catalase Diminishes Oxidative Cysteine Modifications of Cardiac Proteins.
    PloS one, 2015, Volume: 10, Issue:12

    Topics: Aging; Animals; Catalase; Cysteine; Female; Heart Diseases; Humans; Hydrogen Peroxide; Male; Mice; Mice, Transgenic; Mitochondria, Heart; Muscle Proteins; Myocardium; Oxidation-Reduction; Oxidative Stress; Protein Processing, Post-Translational; Signal Transduction

2015
Ageing-induced changes in the redox status of peripheral motor nerves imply an effect on redox signalling rather than oxidative damage.
    Free radical biology & medicine, 2016, Volume: 94

    Topics: Aging; Animals; Cysteine; Electron Spin Resonance Spectroscopy; Humans; Mice; Muscle Fibers, Skeletal; Muscle, Skeletal; Nerve Degeneration; Neuromuscular Junction; Oxidation-Reduction; Oxidative Stress; Peripheral Nerves; Peroxiredoxin VI; Proteomics; Sciatic Nerve; Superoxides

2016
Natural thioallyl compounds increase oxidative stress resistance and lifespan in Caenorhabditis elegans by modulating SKN-1/Nrf.
    Scientific reports, 2016, Feb-22, Volume: 6

    Topics: Aging; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cysteine; DNA-Binding Proteins; Forkhead Transcription Factors; Garlic; Gene Expression Regulation; Longevity; Oxidative Stress; Reactive Oxygen Species; Signal Transduction; Transcription Factors

2016
Reversible glutathionylation of Sir2 by monothiol glutaredoxins Grx3/4 regulates stress resistance.
    Free radical biology & medicine, 2016, Volume: 96

    Topics: Aging; Amino Acid Sequence; Cysteine; Disulfides; Glutaredoxins; Glutathione; Mutagenesis, Site-Directed; Oxidation-Reduction; Oxidative Stress; Oxidoreductases; Protein Processing, Post-Translational; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Sirtuin 2; Stress, Physiological

2016
Vitamin C and E Supplements Enhance the Antioxidant Capacity of Erythrocytes Obtained from Aged Rats.
    Rejuvenation research, 2017, Volume: 20, Issue:2

    Topics: Aging; Animals; Antioxidants; Ascorbic Acid; Cysteine; Dietary Supplements; Erythrocyte Deformability; Erythrocytes; Glutathione; Male; Oxidants; Oxidative Stress; Rats, Wistar; Vitamin E

2017
Differential Regulation of the Extracellular Cysteine/Cystine Redox State (EhCySS) by Lung Fibroblasts from Young and Old Mice.
    Oxidative medicine and cellular longevity, 2016, Volume: 2016

    Topics: Actins; Aging; Animals; Cells, Cultured; Cysteine; Cystine; Fibroblasts; Fibronectins; Lung; Mice; Oxidation-Reduction; Superoxide Dismutase; Transforming Growth Factor beta

2016
The oxidized thiol proteome in aging and cataractous mouse and human lens revealed by ICAT labeling.
    Aging cell, 2017, Volume: 16, Issue:2

    Topics: Adolescent; Aged; Aging; Amino Acid Sequence; Animals; Antioxidants; Cataract; Child; Child, Preschool; Cross-Linking Reagents; Cysteine; Glutathione; Humans; Intermediate Filaments; Isotope Labeling; Lens, Crystalline; Mice, Knockout; Oxidation-Reduction; Peptides; Protein Deglycase DJ-1; Proteome; Sulfhydryl Compounds

2017
[Clinical evaluation of serum albumin reductivity in patients with renal dysfunction: a comparison between conservative renal failure patients and hemodialysis patients].
    Nihon Jinzo Gakkai shi, 2008, Volume: 50, Issue:4

    Topics: Adult; Aged; Aging; Chromatography, High Pressure Liquid; Cysteine; Female; Gas Chromatography-Mass Spectrometry; Glomerular Filtration Rate; Homocysteine; Humans; Male; Middle Aged; Oxidation-Reduction; Renal Dialysis; Renal Insufficiency; Serum Albumin

2008
L-cysteine influx in erythrocytes as a function of human age.
    Rejuvenation research, 2008, Volume: 11, Issue:3

    Topics: Adult; Aged; Aging; Cysteine; Erythrocytes; Female; Humans; Male; Middle Aged; Oxidative Stress

2008
Cysteinylation and homocysteinylation of plasma protein thiols during ageing of healthy human beings.
    Journal of cellular and molecular medicine, 2009, Volume: 13, Issue:9B

    Topics: Adult; Aged; Aged, 80 and over; Aging; Antioxidants; Chromatography, High Pressure Liquid; Cysteine; Female; Homocysteine; Humans; Male; Middle Aged; Oxidative Stress; Risk; Sulfhydryl Compounds

2009
Proteomic analysis of the oxidation of cysteine residues in human age-related nuclear cataract lenses.
    Biochimica et biophysica acta, 2008, Volume: 1784, Issue:12

    Topics: Aging; Cataract; Crystallins; Cysteine; Disulfides; Humans; Lens Nucleus, Crystalline; Oxidation-Reduction; Proteomics

2008
Erythrocyte glutathione and plasma cysteine concentrations in young versus old dogs.
    Journal of the American Veterinary Medical Association, 2009, Jan-01, Volume: 234, Issue:1

    Topics: Age Factors; Aging; Animal Feed; Animals; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Cysteine; Dogs; Erythrocytes; Female; Glutathione; Male; Nutritional Status; Sex Factors

2009
Accumulation of overoxidized Peroxiredoxin III in aged rat liver mitochondria.
    Biochimica et biophysica acta, 2009, Volume: 1787, Issue:7

    Topics: Acetylcarnitine; Aging; Animals; Cysteine; Electrophoresis, Gel, Two-Dimensional; Male; Mass Spectrometry; Mitochondria, Liver; Molecular Weight; Nootropic Agents; Oxidation-Reduction; Peroxiredoxins; Rats; Rats, Inbred F344; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2009
Methylmercury speciation influences brain gene expression and behavior in gestationally-exposed mice pups.
    Toxicological sciences : an official journal of the Society of Toxicology, 2009, Volume: 110, Issue:2

    Topics: Aging; Animal Nutritional Physiological Phenomena; Animals; Animals, Newborn; Behavior, Animal; Body Burden; Brain; Cysteine; Diet; Female; Food Contamination; Gene Expression Profiling; Gene Expression Regulation; Gestational Age; Maternal Nutritional Physiological Phenomena; Mercury Poisoning, Nervous System; Methylmercury Compounds; Mice; Mice, Inbred BALB C; Oligonucleotide Array Sequence Analysis; Pregnancy; Prenatal Exposure Delayed Effects; Reflex; Reproduction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Water Pollutants, Chemical

2009
Impaired nuclear functions lead to increased senescence and inefficient differentiation in human myoblasts with a dominant p.R545C mutation in the LMNA gene.
    European journal of cell biology, 2009, Volume: 88, Issue:10

    Topics: Aging; Amino Acid Substitution; Antibodies; Bisbenzimidazole; Carbocyanines; Case-Control Studies; Cell Culture Techniques; Cell Differentiation; Cell Nucleus; Cells, Cultured; Cysteine; Female; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Lamin Type A; Male; Muscular Dystrophy, Emery-Dreifuss; Mutation, Missense; Myoblasts; Point Mutation; Xanthenes

2009
Revisiting brain reserve hypothesis in frontotemporal dementia: evidence from a brain perfusion study.
    Dementia and geriatric cognitive disorders, 2009, Volume: 28, Issue:2

    Topics: Aged; Aging; Behavior; Brain; Brain Mapping; Cerebrovascular Circulation; Cysteine; Dementia; Education; Female; Humans; Image Processing, Computer-Assisted; Leisure Activities; Male; Middle Aged; Neuropsychological Tests; Occupations; Organotechnetium Compounds; Radionuclide Imaging; Radiopharmaceuticals

2009
Differential effect of L-cysteine in isolated whole-bladder preparations from neonatal and adult rats.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 333, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Calcium Channels; Cysteine; Female; In Vitro Techniques; Large-Conductance Calcium-Activated Potassium Channels; Male; Muscle Contraction; Muscle, Smooth; Rats; Rats, Wistar; Urinary Bladder

2010
The redox state of human serum albumin in eye diseases with and without complications.
    Acta ophthalmologica, 2011, Volume: 89, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aging; Biomarkers; Blood Pressure; Chromatography, High Pressure Liquid; Cysteine; Diabetes Complications; Eye Diseases; Female; Humans; Hypertension; Male; Middle Aged; Oxidation-Reduction; Oxidative Stress; Serum Albumin

2011
Upregulation of Nox4 by hypertrophic stimuli promotes apoptosis and mitochondrial dysfunction in cardiac myocytes.
    Circulation research, 2010, Apr-16, Volume: 106, Issue:7

    Topics: Aconitate Hydratase; Aging; Animals; Apoptosis; Cardiomegaly; Cell Proliferation; Cells, Cultured; Cysteine; Disease Models, Animal; Enzyme Inhibitors; Fibrosis; Genotype; Humans; Mice; Mice, Transgenic; Mitochondria, Heart; Myocytes, Cardiac; NADH Dehydrogenase; NADPH Oxidase 4; NADPH Oxidases; Onium Compounds; Oxidation-Reduction; Oxidative Stress; Phenotype; Rats; Rats, Wistar; Rotenone; Superoxides; Transfection; Uncoupling Agents; Up-Regulation; Ventricular Dysfunction, Left; Ventricular Function, Left

2010
S-Nitrosylation of DRP1 does not affect enzymatic activity and is not specific to Alzheimer's disease.
    Journal of Alzheimer's disease : JAD, 2010, Volume: 20 Suppl 2

    Topics: Aging; Alzheimer Disease; Biotin; Brain; Cell Line, Transformed; Cysteine; Dithiothreitol; Dynamins; GTP Phosphohydrolases; Humans; Microscopy, Electron, Transmission; Microtubule-Associated Proteins; Mitochondrial Diseases; Mitochondrial Proteins; Postmortem Changes; Protein Multimerization

2010
Oxidation and reduction of cysteines in the intermembrane space of mitochondria: multiple facets of redox control.
    Antioxidants & redox signaling, 2010, Nov-01, Volume: 13, Issue:9

    Topics: Aging; Apoptosis; Cysteine; Cytosol; Electron Transport; Endoplasmic Reticulum; Eukaryotic Cells; Humans; Intracellular Membranes; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Membranes; Mitochondrial Proteins; Oxidation-Reduction; Protein Disulfide Reductase (Glutathione); Protein Transport; Reactive Oxygen Species; Signal Transduction

2010
Quantitative biometric phenotype analysis in mouse lenses.
    Molecular vision, 2010, Jun-08, Volume: 16

    Topics: Aging; alpha-Crystallin A Chain; Animals; Arginine; Biometry; Cataract; Cysteine; Eye Abnormalities; Genotype; Heterozygote; Homozygote; Image Processing, Computer-Assisted; Lens, Crystalline; Mice; Mice, Knockout; Mice, Transgenic; Mutation; Organ Size; Phenotype; Solubility

2010
A combination antioxidant therapy prevents age-related hearing loss in C57BL/6 mice.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2010, Volume: 143, Issue:3

    Topics: Aging; Animals; Antioxidants; Ascorbic Acid; Auditory Threshold; Cysteine; Disease Models, Animal; Drug Therapy, Combination; Evoked Potentials, Auditory, Brain Stem; Glutathione; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Presbycusis; Vitamin B Complex

2010
Protective effects on mitochondria and anti-aging activity of polysaccharides from cultivated fruiting bodies of Cordyceps militaris.
    The American journal of Chinese medicine, 2010, Volume: 38, Issue:6

    Topics: Aging; Animals; Antioxidants; Cordyceps; Cysteine; Disease Models, Animal; Dose-Response Relationship, Drug; Fruiting Bodies, Fungal; Galactose; Hydroxyl Radical; Injections, Subcutaneous; Liver; Male; Mice; Mice, Inbred Strains; Mitochondria; Mitochondrial Diseases; Phytotherapy; Polysaccharides; Reactive Oxygen Species; Superoxides; Thiobarbituric Acid Reactive Substances

2010
Serum folate is significantly correlated with plasma cysteine concentrations in healthy industry workers.
    Annals of nutrition & metabolism, 2011, Volume: 58, Issue:1

    Topics: Adult; Aged; Aging; Cardiovascular Diseases; Cysteine; Extraction and Processing Industry; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Neoplasms; Norway; Risk Factors; Triglycerides; Young Adult

2011
Differential cysteine depletion in respiratory chain complexes enables the distinction of longevity from aerobicity.
    Mechanisms of ageing and development, 2011, Volume: 132, Issue:4

    Topics: Aerobiosis; Aging; Animals; Cell Nucleus; Cysteine; Electron Transport; Humans; Membrane Proteins; Mitochondria; Oxidative Stress; Oxygen Consumption; Phylogeny; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Sulfhydryl Compounds; Time Factors

2011
Quinoprotein adducts accumulate in the substantia nigra of aged rats and correlate with dopamine-induced toxicity in SH-SY5Y cells.
    Neurochemical research, 2011, Volume: 36, Issue:11

    Topics: Aging; Animals; Cysteine; Dopamine; Dopamine Antagonists; Dopaminergic Neurons; Humans; Hydroquinones; Isothiocyanates; Lipid Peroxidation; Male; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Substantia Nigra; Sulfoxides; Thiocyanates; Tumor Cells, Cultured

2011
Is protein methylation in the human lens a result of non-enzymatic methylation by S-adenosylmethionine?
    Experimental eye research, 2012, Volume: 99

    Topics: Adolescent; Adult; Aged; Aging; beta-Crystallin A Chain; Chromatography, High Pressure Liquid; Cysteine; Histidine; Humans; Lens, Crystalline; Mass Spectrometry; Methylation; Middle Aged; Protein Methyltransferases; Protein Processing, Post-Translational; Proteomics; S-Adenosylmethionine; Tissue Donors; Young Adult

2012
Cerebral small vessel disease in aging and Alzheimer's disease: a comparative study using MRI and SPECT.
    European journal of neurology, 2013, Volume: 20, Issue:2

    Topics: Aged; Aging; Alzheimer Disease; Brain; Cerebral Small Vessel Diseases; Cysteine; Female; Humans; Leukoaraiosis; Magnetic Resonance Imaging; Male; Nerve Fibers, Myelinated; Neuroimaging; Organotechnetium Compounds; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon

2013
Structural features of isomerizable aspartyl residues in human α-crystallins.
    Molecular vision, 2012, Volume: 18

    Topics: Aging; alpha-Crystallin A Chain; alpha-Crystallin B Chain; Amino Acid Sequence; Aspartic Acid; Cloning, Molecular; Cysteine; Escherichia coli; Humans; Isomerism; Lens, Crystalline; Metalloendopeptidases; Molecular Sequence Data; Proteolysis; Recombinant Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2012
Brain perfusion SPECT in the mouse: normal pattern according to gender and age.
    NeuroImage, 2012, Volume: 63, Issue:4

    Topics: Aging; Animals; Brain; Cerebrovascular Circulation; Cysteine; Female; Functional Laterality; Image Processing, Computer-Assisted; Male; Mice; Mice, Inbred C57BL; Organotechnetium Compounds; Perfusion; Radiopharmaceuticals; Sex Characteristics; Technetium Tc 99m Exametazime; Tomography, Emission-Computed, Single-Photon

2012
Transsulfuration pathway thiols and methylated arginines: the Hunter Community Study.
    PloS one, 2013, Volume: 8, Issue:1

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Aging; Amidohydrolases; Arginine; Australia; C-Reactive Protein; Cardiovascular Diseases; Cohort Studies; Community Medicine; Cysteine; Dipeptides; Female; Glutathione; Homocysteine; Humans; Male; Middle Aged; Taurine

2013
Down-regulation of gamma-glutamylcysteine synthetase regulatory subunit gene expression in rat brain tissue during aging.
    Journal of neuroscience research, 2002, May-01, Volume: 68, Issue:3

    Topics: Aging; Animals; Brain; Cysteine; Dipeptides; Down-Regulation; gamma-Glutamyltransferase; Gene Expression Regulation, Enzymologic; Glutathione; Glutathione Disulfide; Glutathione Reductase; Glutathione Synthase; Male; Nerve Degeneration; Oxidative Stress; Rats; Rats, Inbred F344; Regulatory Sequences, Nucleic Acid

2002
The production of hydrogen sulfide is regulated by testosterone and S-adenosyl-L-methionine in mouse brain.
    Journal of neurochemistry, 2002, Volume: 83, Issue:1

    Topics: Age Factors; Aging; Animals; Brain; Chromatography, High Pressure Liquid; Cystathionine beta-Synthase; Cysteine; Female; Hydrogen Sulfide; Male; Mice; Mice, Inbred BALB C; S-Adenosylmethionine; Sex Factors; Testosterone

2002
The gamma-glutamyltransferase activity and non-protein sulfhydryl compounds levels in rat kidney of different age groups.
    Acta biochimica Polonica, 2002, Volume: 49, Issue:2

    Topics: Aging; Animals; Cysteine; gamma-Glutamyltransferase; Kidney; Rats; Rats, Wistar; Reactive Oxygen Species; Sulfhydryl Compounds

2002
Redox analysis of human plasma allows separation of pro-oxidant events of aging from decline in antioxidant defenses.
    Free radical biology & medicine, 2002, Nov-01, Volume: 33, Issue:9

    Topics: Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Aging; Cysteine; Disulfides; Female; Glutathione; Glutathione Disulfide; Humans; Kinetics; Male; Middle Aged; Models, Chemical; Oxidation-Reduction; Oxidative Stress; Reference Values; Sex Distribution; Sulfhydryl Compounds

2002
In vitro cultivation of Hysterothylacium aduncum (Nematoda: Anisakidae) from 3rd-stage larvae to egg-laying adults.
    Parasitology, 2002, Volume: 125, Issue:Pt 5

    Topics: Aging; Animals; Carbon Dioxide; Culture Media; Cysteine; Fish Diseases; Glutathione; Hydrogen-Ion Concentration; Larva; Nematoda; Oviposition; Pepsin A; Perciformes; Trypsin

2002
S-methylated cysteines in human lens gamma S-crystallins.
    Biochemistry, 2002, Dec-17, Volume: 41, Issue:50

    Topics: Adult; Aged; Aged, 80 and over; Aging; Chymotrypsin; Cysteine; gamma-Crystallins; Humans; Infant, Newborn; Lens, Crystalline; Methylation; Middle Aged; Peptide Fragments; Spectrometry, Mass, Electrospray Ionization; Sulfhydryl Compounds

2002
Effects of aging on brain perfusion and serotonin-2A receptor binding in the normal canine brain measured with single photon emission tomography.
    Progress in neuro-psychopharmacology & biological psychiatry, 2002, Volume: 26, Issue:7-8

    Topics: Aging; Animals; Cerebral Cortex; Cysteine; Dogs; Female; Iodine Radioisotopes; Ligands; Male; Organotechnetium Compounds; Piperidines; Radiopharmaceuticals; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Regional Blood Flow; Tomography, Emission-Computed, Single-Photon

2002
The part played by disulphide and methyl groups in ageing processes.
    Rumanian medical review, 1961, Volume: 5

    Topics: Aging; Cysteine; Cystine; Disulfides; Glutathione; Humans; Methionine

1961
[Studies on the behavior of sulfhydryl compounds in regressive vital processes in the lens].
    Bericht uber die Zusammenkunft. Deutsche Ophthalmologische Gesellschaft, 1961, Volume: 64

    Topics: Aging; Cysteine; Fabaceae; Humans; Lens, Crystalline; Lenses; Sulfhydryl Compounds

1961
[Research on the relation between vitamin coenzymes and corresponding enzymes in relation to the age of the animal and under the influence of certain substances proper to the organism].
    Biokhimiia (Moscow, Russia), 1963, Volume: 28

    Topics: Acetylesterase; Adenine Nucleotides; Aging; Alanine Transaminase; Amino Acids; Animals; Aspartate Aminotransferases; Coenzymes; Cysteine; D-Alanine Transaminase; Folic Acid; Humans; NAD; Niacin; Niacinamide; Pantothenic Acid; Pyridoxine; Riboflavin; Thiamine; Thiamine Pyrophosphate; Vitamins

1963
[Glutaminase activity in the cerebral cortex of rats of different ages and the effect of cysteine on glutaminase in the brain of aged animals].
    Ukrains'kyi biokhimichnyi zhurnal, 1963, Volume: 35

    Topics: Aging; Animals; Brain; Cerebral Cortex; Cysteine; Glutaminase; Rats

1963
[Biochemical aspects of the aging process in the central nervous system].
    Giornale di gerontologia, 1962, Volume: 10

    Topics: Aging; Central Nervous System; Corrinoids; Cysteine; Folic Acid; Humans; Proteins; Pyridoxine; Sulfur; Vitamin B 12

1962
[Biochemical aspects of the aging process in the central nervous system].
    Revue francaise de gerontologie, 1963, Volume: 9

    Topics: Aging; Amino Acids; Central Nervous System; Cerebellum; Corrinoids; Cysteine; Humans; Nervous System; Pyridoxine; Vitamin B 12; Vitamin B Complex

1963
[STUDY OF THE ACTION OF CYSTEINE ON THE DISTURBED BALANCE OF AMINO ACIDS IN THE PITUITARY GLAND, ADRENAL GLANDS, THYROID, OVARY AND TESTIS, IN AGED ANIMALS].
    Studii si cercetari de endocrinologie, 1963, Volume: 14

    Topics: Adrenal Glands; Aging; Amino Acids; Animals; Cysteine; Female; Humans; Male; Ovary; Pituitary Gland; Proteins; Rats; Research; Testis; Thyroid Gland

1963
[BIOCHEMICAL ASPECTS OF THE AGING PROCESS. II. THE EFFECT OF CYSTEINE AND VITAMINS PLAYING A ROLE IN SULFUR METHYLATION AND METABOLISM ON AMINO ACID METABOLISM IN THE SPINAL CORD OF RATS OF DIFFERENT AGES].
    Zeitschrift fur Alternsforschung, 1963, Volume: 17

    Topics: Aging; Amino Acids; Corrinoids; Cysteine; Folic Acid; Methylation; Pharmacology; Proteins; Pyridoxine; Rats; Research; Spinal Cord; Sulfur; Vitamin A; Vitamin B 12; Vitamin K; Vitamins

1963
[BIOCHEMICAL ASPECTS OF THE AGING PROCESS. III. THE EFFECT OF CYSTEINE AND VITAMINS PLAYING A ROLE IN METHYLATION AND METABOLISM OF SULFUR ON AMINO ACID METABOLISM IN THE MESENCEPHALON OF RATS OF DIFFERENT AGES].
    Zeitschrift fur Alternsforschung, 1963, Volume: 17

    Topics: Aging; Amino Acids; Corrinoids; Cysteine; Folic Acid; Mesencephalon; Methylation; Pharmacology; Proteins; Pyridoxine; Rats; Research; Sulfur; Vitamin A; Vitamin B 12; Vitamin K; Vitamins

1963
THE INFLUENCE OF CYSTEINE ON COLLAGEN FIBRES.
    Gerontologia, 1963, Volume: 49

    Topics: Aging; Body Weight; Collagen; Cysteine; Folic Acid; Metabolism; Pharmacology; Rats; Research

1963
OXIDIZED GLUTATHIONE AS A TEST OF SENESCENCE.
    Gerontologia, 1964, Volume: 49

    Topics: Aging; Animals; Biomedical Research; Blood Chemical Analysis; Corrinoids; Cysteine; Folic Acid; Geriatrics; Glutamates; Glutathione; Glutathione Disulfide; Hematinics; Lidocaine; Metabolism; Pyridoxine; Rabbits; Rats; Research; Vitamin B 12

1964
[ACTION OF CYSTEINE ON SOME INDICES OF BLOOD LIPID DISORDER IN RABBIT WITH EXPERIMENTAL ATHEROSCLEROSIS AND IN AGED RABBITS].
    Revue francaise de gerontologie, 1965, Volume: 11

    Topics: Aging; Arteriosclerosis; Atherosclerosis; Cysteine; Lipid Metabolism Disorders; Lipidoses; Lipids; Pharmacology; Rabbits; Research; Toxicology

1965
[STUDY OF VITAMIN B 12, FOLIC ACID AND PANTOTHENIC ACID IN RABBITS AS A FUNCTION OF AGE AND IN THOSE WITH EXPERIMENTAL ATHEROSCLEROSIS AS WELL AS IN AGED RABBITS TREATED WITH CYSTEINE-FOLIC ACID].
    Revue francaise de gerontologie, 1965, Volume: 11

    Topics: Aging; Arteriosclerosis; Atherosclerosis; Cysteine; Folic Acid; Humans; Metabolism; Pantothenic Acid; Rabbits; Research; Vitamin B 12; Vitamin B Complex

1965
[Biochemistry of the biology of the aged. Cysteine, essential factor in the restoration of the biochemical equilibrium of the aged toward that which is proper for the young body].
    Revue des sciences medicales, 1961, Volume: 6

    Topics: Aging; Biochemical Phenomena; Biochemistry; Biology; Cysteine; Humans

1961
[Biochemistry of biological aging processes. 3. The blood glutathione level in animals of different ages and the effect of administration of cystein, vitamin B6, vitamin B12 and folic acid on the glutathione level of the aged animal].
    Zeitschrift fur Alternsforschung, 1962, Volume: 15

    Topics: Aging; Animals; Corrinoids; Cysteine; Folic Acid; Glutathione; Vitamin B 12; Vitamin B 6; Vitamin B Complex

1962
Effect of age increase on metabolism and toxicity of ethanol in female rats.
    Life sciences, 2003, Dec-12, Volume: 74, Issue:4

    Topics: Aging; Animals; Central Nervous System Depressants; Cysteine; Ethanol; Female; Glutathione; Hepatitis, Alcoholic; Lipid Peroxidation; Liver; Oxidative Stress; Rats; Rats, Sprague-Dawley; Triglycerides

2003
The identification of a reaction site of glutathione mixed-disulphide formation on gammaS-crystallin in human lens.
    The Biochemical journal, 2004, May-01, Volume: 379, Issue:Pt 3

    Topics: Aging; Amino Acid Sequence; Blotting, Western; Cataract; Cysteine; Dimerization; Disulfides; Electrophoresis, Polyacrylamide Gel; gamma-Crystallins; Glutathione; Humans; Lens, Crystalline; Molecular Sequence Data; Molecular Weight

2004
(R)-alpha-lipoic acid reverses the age-related loss in GSH redox status in post-mitotic tissues: evidence for increased cysteine requirement for GSH synthesis.
    Archives of biochemistry and biophysics, 2004, Mar-01, Volume: 423, Issue:1

    Topics: Aging; Animals; Brain; Cysteine; Glutamate-Cysteine Ligase; Glutathione; Kinetics; Male; Myocardium; Oxidation-Reduction; Rats; Thioctic Acid

2004
Age-related changes in glutathione availability and skeletal muscle carbonyl content in healthy rats.
    Experimental gerontology, 2004, Volume: 39, Issue:2

    Topics: Aging; Animals; Body Weight; Cysteine; Glutathione; Liver; Male; Muscle Proteins; Muscle, Skeletal; Organ Size; Oxidative Stress; Rats; Rats, Wistar

2004
Plasma levels of total, free and protein bound thiols as well as sulfane sulfur in different age groups of rats.
    Acta biochimica Polonica, 2004, Volume: 51, Issue:3

    Topics: Aging; Animals; Blood Proteins; Cysteine; Female; Glutathione; Homocysteine; Oxidation-Reduction; Protein Binding; Rats; Rats, Wistar; Sulfhydryl Compounds; Sulfur

2004
The enzymatic activities of the Werner syndrome protein are disabled by the amino acid polymorphism R834C.
    The Journal of biological chemistry, 2004, Dec-31, Volume: 279, Issue:53

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Aging; Alleles; Arginine; Cell Line; Cysteine; DNA; DNA Helicases; DNA, Complementary; Escherichia coli; Exodeoxyribonucleases; Gene Frequency; Genetic Variation; Genotype; Heterozygote; Humans; Hydrolysis; Immunoprecipitation; Models, Genetic; Models, Molecular; Mutation; Plasmids; Polymorphism, Genetic; Protein Structure, Tertiary; RecQ Helicases; Transfection; Werner Syndrome Helicase

2004
Glycation-induced inactivation of NADP(+)-dependent isocitrate dehydrogenase: implications for diabetes and aging.
    Free radical biology & medicine, 2004, Dec-01, Volume: 37, Issue:11

    Topics: Aging; Animals; Antioxidants; Cell Line; Cysteine; Diabetes Mellitus; Fructose; Glucose; Glycosylation; Humans; Isocitrate Dehydrogenase; Lysine; Mice; Mitochondria; Oxidation-Reduction; Oxidative Stress; Rats

2004
The effects of age and hyperhomocysteinemia on the redox forms of plasma thiols.
    The Journal of laboratory and clinical medicine, 2004, Volume: 144, Issue:5

    Topics: Adolescent; Adult; Aged; Aging; Arteriosclerosis; Blood Proteins; Cardiovascular Diseases; Child; Child, Preschool; Cysteine; Disulfides; Glycine; Heart Transplantation; Humans; Hyperhomocysteinemia; Infant; Infant, Newborn; Middle Aged; Oxidation-Reduction; Protein Binding; Renal Insufficiency; Sulfhydryl Compounds

2004
Kinetic characteristics of native gamma-glutamylcysteine ligase in the aging housefly, Musca domestica L.
    Biochemical and biophysical research communications, 2005, Jan-21, Volume: 326, Issue:3

    Topics: Adenosine Triphosphate; Aging; Animals; Buthionine Sulfoximine; Cysteine; Feedback, Physiological; Glutamate-Cysteine Ligase; Glutamic Acid; Glutathione; Houseflies; Kinetics

2005
HIV-1 Tat inhibits neprilysin and elevates amyloid beta.
    AIDS (London, England), 2005, Jan-28, Volume: 19, Issue:2

    Topics: Adult; Aging; AIDS Dementia Complex; Alzheimer Disease; Amyloid beta-Peptides; Brain; Cell Membrane; Cells, Cultured; Cysteine; Frontal Lobe; Gene Products, tat; HIV Infections; HIV-1; Humans; Immunohistochemistry; Middle Aged; Neprilysin; tat Gene Products, Human Immunodeficiency Virus

2005
The protective effect of L-cysteine and glutathione on the adult and aged rat brain (Na+,K+)-ATPase and Mg2+-ATPase activities in galactosemia in vitro.
    Metabolic brain disease, 2005, Volume: 20, Issue:1

    Topics: Age Factors; Aging; Animals; Antioxidants; Brain; Ca(2+) Mg(2+)-ATPase; Cysteine; Enzyme Activation; Free Radicals; Galactosemias; Glutathione; Male; Oxidative Stress; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Subcellular Fractions

2005
Hepatocellular carcinoma and the penetrance of HFE C282Y mutations: a cross sectional study.
    BMC gastroenterology, 2005, Jun-01, Volume: 5

    Topics: Aging; Carcinoma, Hepatocellular; Case-Control Studies; Cross-Sectional Studies; Cysteine; Female; Genetic Predisposition to Disease; Genotype; Hemochromatosis Protein; Histocompatibility Antigens Class I; Homozygote; Humans; Liver Neoplasms; Male; Membrane Proteins; Middle Aged; Mutation; Penetrance; Tyrosine

2005
Age-related decline in actomyosin function.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2005, Volume: 60, Issue:4

    Topics: Actins; Actomyosin; Aging; Animals; Cysteine; Female; Male; Muscle Contraction; Muscle Fibers, Skeletal; Muscle, Skeletal; Myosin Subfragments; Myosins; Oxidation-Reduction; Rats; Rats, Inbred F344; Structure-Activity Relationship

2005
Effect of antioxidant-enriched diets on glutathione redox status in tissue homogenates and mitochondria of the senescence-accelerated mouse.
    Free radical biology & medicine, 2005, Aug-15, Volume: 39, Issue:4

    Topics: Aging; Animals; Antioxidants; Brain; Chromatography, High Pressure Liquid; Cysteine; Diet; Female; Glutathione; Glutathione Disulfide; Kidney; Liver; Male; Methionine; Mice; Mitochondria; Muscle, Skeletal; Myocardium; Oxidation-Reduction

2005
Quantitative mapping of oxidation-sensitive cysteine residues in SERCA in vivo and in vitro by HPLC-electrospray-tandem MS: selective protein oxidation during biological aging.
    The Biochemical journal, 2006, Mar-15, Volume: 394, Issue:Pt 3

    Topics: Aging; Amino Acid Sequence; Animals; Calcium-Transporting ATPases; Chromatography, High Pressure Liquid; Cysteine; Fluorescent Dyes; Oxidation-Reduction; Rats; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Spectrometry, Mass, Electrospray Ionization; Staining and Labeling; Time Factors

2006
Neuronal glutathione deficiency and age-dependent neurodegeneration in the EAAC1 deficient mouse.
    Nature neuroscience, 2006, Volume: 9, Issue:1

    Topics: Acetylcysteine; Aging; Animals; Behavior, Animal; Bicuculline; Blotting, Western; Brain; Cysteine; Excitatory Amino Acid Transporter 3; GABA Antagonists; Genotype; Glutathione; Immunohistochemistry; Mice; Mice, Knockout; Nerve Degeneration; Neurons; Oxidants; Oxidative Stress

2006
Methionine kinetics are altered in the elderly both in the basal state and after vaccination.
    The American journal of clinical nutrition, 2006, Volume: 83, Issue:2

    Topics: Adult; Aged; Aging; Carbon Isotopes; Cysteine; Deuterium; Female; Homocysteine; Humans; Inflammation; Isotope Labeling; Male; Mathematics; Methionine; Methylation; Nutritional Requirements; Postprandial Period; Vaccination

2006
Antioxidative activity and ameliorative effects of memory impairment of sulfur-containing compounds in Allium species.
    BioFactors (Oxford, England), 2006, Volume: 26, Issue:2

    Topics: Aging; Allium; Animals; Antioxidants; Cysteine; Disulfides; Hippocampus; Humans; Lipid Peroxides; Lipoproteins, LDL; Male; Maze Learning; Memory; Mice; Onions; Phosphatidylcholines; Plant Extracts; Sulfides

2006
Strategies for dissecting genetic-environmental interactions in neurodegenerative disorders.
    Neurotoxicology, 2006, Volume: 27, Issue:5

    Topics: Adult; Age Factors; Age of Onset; Aged; Aged, 80 and over; Aging; alpha 1-Antitrypsin; Analysis of Variance; Apolipoprotein E4; Apolipoproteins E; Chi-Square Distribution; Cysteine; DNA Mutational Analysis; Environment; Female; Gene Frequency; Genetic Predisposition to Disease; Hemochromatosis; Humans; Male; Middle Aged; Mutation; Neurodegenerative Diseases; Phenotype; Retrospective Studies; Tryptophan

2006
Mutational analysis of DJ-1 in Drosophila implicates functional inactivation by oxidative damage and aging.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, Aug-15, Volume: 103, Issue:33

    Topics: Aging; Animals; Animals, Genetically Modified; Cysteine; DNA Mutational Analysis; Drosophila melanogaster; Drosophila Proteins; Herbicides; Humans; Mice; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Oxidative Stress; Paraquat; Parkinson Disease; Protein Deglycase DJ-1

2006
Age-related influence on thiol, disulfide, and protein-mixed disulfide levels in human plasma.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2006, Volume: 61, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Aging; Chromatography, High Pressure Liquid; Cysteine; Disulfides; Female; Glutathione; Humans; Male; Middle Aged; Oxidation-Reduction; Sulfhydryl Compounds

2006
Caspase-2 deficiency enhances aging-related traits in mice.
    Mechanisms of ageing and development, 2007, Volume: 128, Issue:2

    Topics: Adipose Tissue; Aging; Animals; Apoptosis; Bone Density; Bone Resorption; Caspase 2; Cysteine; Hair; Liver; Longevity; Mice; Mice, Knockout; Neoplasms; Oxidative Stress; Proteins; Survival Rate

2007
A reducing redox environment promotes C2C12 myogenesis: implications for regeneration in aged muscle.
    Cell biology international, 2007, Volume: 31, Issue:6

    Topics: Aging; Animals; Basic Helix-Loop-Helix Transcription Factors; Caspase 3; Cell Differentiation; Cysteine; Enzyme Activation; Free Radical Scavengers; Gene Expression Regulation; Glutathione; Mice; Muscle Development; Muscle Fibers, Skeletal; Muscle, Skeletal; Myoblasts, Skeletal; Myosin Heavy Chains; Oxidation-Reduction; Oxygen; p38 Mitogen-Activated Protein Kinases; Peroxides; Reactive Oxygen Species; Regeneration

2007
Aged garlic extract and S-allyl cysteine prevent formation of advanced glycation endproducts.
    European journal of pharmacology, 2007, Apr-30, Volume: 561, Issue:1-3

    Topics: Aging; Antioxidants; Cysteine; Diabetes Complications; Electrophoresis, Polyacrylamide Gel; Free Radicals; Garlic; Glucose; Glycation End Products, Advanced; Humans; Hyperglycemia; Muramidase; Peptide Fragments; Plant Extracts; Pyridoxamine; Pyruvaldehyde; Ribose

2007
The archetypal R90C CADASIL-NOTCH3 mutation retains NOTCH3 function in vivo.
    Human molecular genetics, 2007, Apr-15, Volume: 16, Issue:8

    Topics: Aging; Animals; Arginine; CADASIL; Cerebral Arteries; Cysteine; Immunoglobulin J Recombination Signal Sequence-Binding Protein; Intracranial Arterial Diseases; Lac Operon; Mice; Mice, Knockout; Mutant Proteins; Mutation, Missense; Protein Structure, Tertiary; Receptor, Notch3; Receptors, Notch; Transgenes

2007
Methionine sulfoxide reduction and the aging process.
    Annals of the New York Academy of Sciences, 2007, Volume: 1100

    Topics: Aging; Antioxidants; Cysteine; Gene Deletion; Methionine; Methionine Sulfoxide Reductases; Models, Genetic; Oxidative Stress; Oxidoreductases; Reactive Oxygen Species; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sulfur; Time Factors

2007
Age-associated perturbations in glutathione synthesis in mouse liver.
    The Biochemical journal, 2007, Aug-01, Volume: 405, Issue:3

    Topics: Aging; Amino Acid Sequence; Animals; Cysteine; Dipeptides; Glutamate-Cysteine Ligase; Glutathione; Glutathione Disulfide; Homocysteine; Liver; Male; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Phylogeny

2007
Reversible binding of kynurenine to lens proteins: potential protection by glutathione in young lenses.
    Investigative ophthalmology & visual science, 2007, Volume: 48, Issue:8

    Topics: Aging; Animals; Binding, Competitive; Cattle; Crystallins; Cysteine; Glutathione; Histidine; Hydrogen-Ion Concentration; In Vitro Techniques; Ketones; Kynurenine; Lens, Crystalline; Protein Processing, Post-Translational; Ultraviolet Rays

2007
DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Sep-11, Volume: 104, Issue:37

    Topics: Aging; Animals; Cysteine; DNA Mutational Analysis; Exons; Gene Deletion; Glutathione Peroxidase; Humans; Hydrogen Peroxide; Immunohistochemistry; Mass Spectrometry; Mice; Mice, Knockout; Mitochondria; Oncogene Proteins; Oxidation-Reduction; Parkinson Disease; Peroxidase; Peroxidases; Peroxiredoxins; Protein Deglycase DJ-1; Superoxide Dismutase

2007
Diurnal variation in glutathione and cysteine redox states in human plasma.
    The American journal of clinical nutrition, 2007, Volume: 86, Issue:4

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Aging; Area Under Curve; Cardiovascular Diseases; Circadian Rhythm; Cysteine; Cystine; Female; Glutathione; Glutathione Disulfide; Humans; Male; Middle Aged; Oxidation-Reduction; Oxidative Stress; Postprandial Period; Sex Factors

2007
Mitochondrially encoded cysteine predicts animal lifespan.
    Aging cell, 2008, Volume: 7, Issue:1

    Topics: Aging; Animals; Computational Biology; Cysteine; DNA, Mitochondrial; Free Radicals; Humans; Longevity; Mitochondria; Mitochondrial Proteins; Models, Molecular; Phylogeny

2008
Physiological significance of reactive cysteine residues of Keap1 in determining Nrf2 activity.
    Molecular and cellular biology, 2008, Volume: 28, Issue:8

    Topics: Adaptor Proteins, Signal Transducing; Aging; Animals; Cells, Cultured; Cysteine; Cytoskeletal Proteins; Gene Expression Regulation; Genes, Lethal; Homeostasis; Hydroquinones; Kelch-Like ECH-Associated Protein 1; Mice; Mice, Transgenic; Mutation; NF-E2-Related Factor 2

2008
Nutritional significance of increase in gamma-glutamyltransferase in mouse liver before birth.
    The Journal of nutrition, 1980, Volume: 110, Issue:3

    Topics: Adaptation, Physiological; Aging; Animals; Cysteine; Female; gamma-Glutamyltransferase; Glutathione; Liver; Maternal-Fetal Exchange; Mice; Pregnancy; Protein Biosynthesis

1980
A study of intestinal copper-binding proteins in mottled mice.
    Chemico-biological interactions, 1983, Jul-01, Volume: 45, Issue:1

    Topics: Aging; Animals; Brain Diseases, Metabolic; Carrier Proteins; Copper; Cysteine; Humans; Intestinal Mucosa; Male; Menkes Kinky Hair Syndrome; Metalloproteins; Metallothionein; Mice; Mice, Mutant Strains; Models, Biological; Zinc

1983
Selective oxidation of cysteine and methionine in normal and senile cataractous lenses.
    Proceedings of the National Academy of Sciences of the United States of America, 1980, Volume: 77, Issue:3

    Topics: Aged; Aging; Cataract; Crystallins; Cysteine; Humans; Lens, Crystalline; Membrane Proteins; Methionine; Middle Aged; Oxidation-Reduction

1980
Cysteine-induced effect on amino acids in neonatal rat brain.
    Experientia, 1982, Mar-15, Volume: 38, Issue:3

    Topics: Aging; Amino Acids; Animals; Animals, Newborn; Brain; Cysteine; Rats; Rats, Inbred Strains

1982
Immaturity of the enzyme activity and the response to inducers of rat liver cysteine dioxygenase during development.
    Journal of biochemistry, 1980, Volume: 88, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Cysteine; Cysteine Dioxygenase; Dioxygenases; Enzyme Induction; Female; Fetus; Half-Life; Hydrocortisone; Kinetics; Liver; Male; Maternal-Fetal Exchange; Oxygenases; Pregnancy; Rats

1980
Effect of cysteine on expression of cystathionine beta-synthase in the rat liver.
    Journal of nutritional science and vitaminology, 1995, Volume: 41, Issue:2

    Topics: Aging; Animals; Base Sequence; Cystathionine beta-Synthase; Cysteine; DNA Primers; Gene Expression Regulation, Enzymologic; Liver; Male; Methionine; Molecular Sequence Data; Rats; Rats, Sprague-Dawley; RNA, Messenger

1995
LH-2: a LIM/homeodomain gene expressed in developing lymphocytes and neural cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Jan-01, Volume: 90, Issue:1

    Topics: Aging; Amino Acid Sequence; Animals; B-Lymphocytes; Base Sequence; Brain; Cell Differentiation; Cell Line; Cloning, Molecular; Cysteine; DNA; Embryo, Mammalian; Gene Expression; Genes, Homeobox; Homeodomain Proteins; In Situ Hybridization; LIM-Homeodomain Proteins; Mice; Molecular Sequence Data; Organ Specificity; Rats; RNA; RNA, Messenger; Sequence Homology, Amino Acid; Transcription Factors; Transcription, Genetic

1993
ATP-sensitive K+ channels of skeletal muscle fibers from young adult and aged rats: possible involvement of thiol-dependent redox mechanisms in the age-related modifications of their biophysical and pharmacological properties.
    Molecular pharmacology, 1994, Volume: 46, Issue:4

    Topics: Acetylcysteine; Adenosine Triphosphate; Aging; Animals; Cysteine; Glyburide; In Vitro Techniques; Male; Muscle, Skeletal; Oxidation-Reduction; Potassium Channels; Rats; Rats, Inbred WKY; Thimerosal

1994
Cysteine restores the activity of ATP-sensitive potassium channels of skeletal muscle fibers of aged rats.
    Annals of the New York Academy of Sciences, 1994, Jun-30, Volume: 717

    Topics: Adenosine Triphosphate; Aging; Animals; Cysteine; In Vitro Techniques; Ion Channel Gating; Membrane Potentials; Muscles; Potassium Channels; Rats

1994
Autocrine signals enable chondrocytes to survive in culture.
    The Journal of cell biology, 1994, Volume: 126, Issue:4

    Topics: Aging; Alkaloids; Animals; Apoptosis; Biological Factors; Cartilage; Cell Survival; Cells, Cultured; Chick Embryo; Culture Media, Conditioned; Cycloheximide; Cysteine; Epithelial Cells; Epithelium; Fibroblast Growth Factor 2; Growth Substances; Humans; Insulin; Kinetics; Lens, Crystalline; Platelet-Derived Growth Factor; Protein Kinase C; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Staurosporine

1994
Glutathione cycle dependency of ferric nitrilotriacetate-induced lipid peroxidation in mouse proximal renal tubules.
    Archives of biochemistry and biophysics, 1993, Feb-15, Volume: 301, Issue:1

    Topics: Aging; Animals; Buthionine Sulfoximine; Cysteine; Fatty Acids; Fatty Acids, Unsaturated; Female; Ferric Compounds; gamma-Glutamyltransferase; Glutathione; Glutathione Synthase; Kidney Cortex; Kidney Medulla; Kidney Tubules, Proximal; Lipid Peroxidation; Male; Methionine Sulfoximine; Mice; Nitrilotriacetic Acid; Sex Characteristics; Thiobarbiturates

1993
Glutamine force-feeding effect on plasma amino-acid concentrations in growing rats fed a cafeteria diet.
    Reproduction, nutrition, development, 1994, Volume: 34, Issue:2

    Topics: Aging; Amino Acids; Animals; Cysteine; Diet; Glutamine; Ornithine; Proline; Rats; Rats, Wistar; Threonine; Tyrosine

1994
Fasting-induced depletion of glutathione in the aging mouse.
    Biochemical pharmacology, 1993, Jul-20, Volume: 46, Issue:2

    Topics: Aging; Animals; Body Weight; Cysteine; Fasting; Glutathione; Kidney; Liver; Male; Mice; Mice, Inbred C57BL; Organ Size; Time Factors

1993
Regulation of cysteine-rich intestinal protein by dexamethasone in the neonatal rat.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Jan-15, Volume: 90, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Base Sequence; Carrier Proteins; Cysteine; Cytosol; Dexamethasone; Gene Expression Regulation; Intestine, Small; LIM Domain Proteins; Molecular Sequence Data; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tissue Distribution; Zinc

1993
A new mixed disulfide species in human cataractous and aged lenses.
    Biochimica et biophysica acta, 1993, Jun-11, Volume: 1157, Issue:2

    Topics: Adult; Aged; Aging; Cataract; Crystallins; Cysteine; Dipeptides; Disulfides; Formates; Glutathione; Humans; Lens, Crystalline; Middle Aged

1993
Further studies on the dynamic changes of glutathione and protein-thiol mixed disulfides in H2O2 induced cataract in rat lenses: distributions and effect of aging.
    Current eye research, 1995, Volume: 14, Issue:10

    Topics: Aging; Animals; Cataract; Crystallins; Culture Media; Cysteine; Disease Models, Animal; Disulfides; Glutathione; Hydrogen Peroxide; Lens Cortex, Crystalline; Lens Nucleus, Crystalline; Lens, Crystalline; Organ Culture Techniques; Oxidants; Oxidative Stress; Rats; Rats, Sprague-Dawley

1995
Investigations into the loss of glutathione from lenses in organ culture.
    Current eye research, 1996, Volume: 15, Issue:7

    Topics: Aging; Animals; Cysteine; Cystine; Glutathione; Lens, Crystalline; Macaca mulatta; Organ Culture Techniques; Oxidative Stress; Rats

1996
Effects of cellular aging on the induction of c-fos by antioxidant treatments.
    Mechanisms of ageing and development, 1996, Mar-29, Volume: 86, Issue:3

    Topics: Aging; Antioxidants; Blotting, Northern; Cells, Cultured; Cysteine; Humans; Proto-Oncogene Mas; Proto-Oncogene Proteins c-fos

1996
Characterization of a human cardiac gene which encodes for a LIM domain protein and is developmentally expressed in myocardial development.
    Journal of molecular and cellular cardiology, 1996, Volume: 28, Issue:6

    Topics: Adult; Aging; Amino Acid Sequence; Animals; Base Sequence; Calcium-Binding Proteins; Cloning, Molecular; Consensus Sequence; Cysteine; DNA, Complementary; Fetus; Gene Expression Regulation, Developmental; Gene Library; Heart; Humans; Infant, Newborn; Molecular Sequence Data; Muscle Development; Muscle Fibers, Slow-Twitch; Muscle, Skeletal; Myocardium; Quail; Rats; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Zinc Fingers

1996
Effects of age on levels of cysteine, glutathione and related enzyme activities in livers of mice and rats and an attempt to replenish hepatic glutathione level of mouse with cysteine derivatives.
    Mechanisms of ageing and development, 1996, Sep-30, Volume: 90, Issue:3

    Topics: Acetylcysteine; Aging; Animals; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; Cystine; Female; Glutathione; Glutathione Disulfide; Liver; Male; Maleates; Mice; Rats; Rats, Inbred F344; Species Specificity

1996
Increase in the intramolecular disulfide bonding of alpha-A crystallin during aging of the human lens.
    Experimental eye research, 1996, Volume: 63, Issue:5

    Topics: Adolescent; Adult; Aged; Aging; Child; Child, Preschool; Chromatography, High Pressure Liquid; Crystallins; Cysteine; Disulfides; Humans; Infant; Infant, Newborn; Lens, Crystalline; Middle Aged; Molecular Weight; Oxidation-Reduction

1996
Age affects glutathione content and glutathione-transferase activity in human gastric mucosa.
    The Italian journal of gastroenterology, 1996, Volume: 28, Issue:9

    Topics: Adult; Aged; Aging; Biopsy; Chromatography, High Pressure Liquid; Cysteine; Female; Gastric Fundus; Gastric Mucosa; Gastroscopy; Glutathione; Glutathione Transferase; Humans; Male; Middle Aged; Pyloric Antrum; Spectrophotometry

1996
Lysine deficiency in postweaned calves fed corn and corn gluten meal diets.
    Journal of animal science, 1997, Volume: 75, Issue:7

    Topics: Aging; Analysis of Variance; Animals; Arginine; Caseins; Cattle; Cattle Diseases; Cysteine; Deficiency Diseases; Diet; Glutamine; Glutens; Glycine; Lysine; Male; Methionine; Nitrogen; Rumen; Serine; Threonine; Zea mays

1997
[Age dependence of cerebral Tc-99m-ECD distribution between preschool and school-age children and adults].
    Nuklearmedizin. Nuclear medicine, 1997, Volume: 36, Issue:4

    Topics: Adolescent; Adult; Aging; Brain; Cerebrovascular Circulation; Child; Child, Preschool; Cysteine; Electroencephalography; Female; Humans; Male; Middle Aged; Organ Specificity; Organotechnetium Compounds; Radiopharmaceuticals; Regional Blood Flow; Regression Analysis; Tomography, Emission-Computed, Single-Photon

1997
Evaluation of protein and energy quality of rendered spent hen meals.
    Poultry science, 1997, Volume: 76, Issue:10

    Topics: Aging; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Cysteine; Diet; Dietary Proteins; Digestion; Energy Intake; Lysine; Male; Methionine; Nutritive Value

1997
[Reduction in mean cerebral blood flow measurements using 99mTc-ECD-SPECT during normal aging].
    Kaku igaku. The Japanese journal of nuclear medicine, 1997, Volume: 34, Issue:10

    Topics: Aged; Aged, 80 and over; Aging; Brain; Cerebral Infarction; Cerebrovascular Circulation; Cysteine; Dementia; Female; Humans; Male; Organotechnetium Compounds; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon

1997
The aggregation in human lens proteins blocks the scavenging of UVA-generated singlet oxygen by ascorbic acid and glutathione.
    Archives of biochemistry and biophysics, 1998, Mar-15, Volume: 351, Issue:2

    Topics: Aging; Antioxidants; Ascorbic Acid; Crystallins; Cysteine; Fluorescence; Free Radical Scavengers; Glutathione; Histidine; Humans; Peroxides; Photolysis; Protein Conformation; Protein Denaturation; Reactive Oxygen Species; Sodium Azide; Tryptophan; Ultraviolet Rays; Urea

1998
Age-related changes of plasma glutathione and cysteine in broilers: effect of dithiothreitol reduction vitro on free and bound pools.
    Poultry science, 1998, Volume: 77, Issue:8

    Topics: Aging; Animals; Blood Proteins; Chickens; Cysteine; Cystine; Dithiothreitol; Glutathione; Glutathione Disulfide; Male; Oxidation-Reduction

1998
Relationship between plasma testosterone and urinary felinine in the growing kitten.
    Physiology & behavior, 1998, Volume: 65, Issue:1

    Topics: Aging; Animals; Body Weight; Cats; Cysteine; Female; Male; Pheromones; Testosterone

1998
Plasma total homocysteine and cysteine in relation to glomerular filtration rate in diabetes mellitus.
    Kidney international, 1999, Volume: 55, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aging; Creatinine; Cysteine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Folic Acid; Glomerular Filtration Rate; Homocysteine; Humans; Insulin; Middle Aged; Vitamin B 12

1999
Protein modification during biological aging: selective tyrosine nitration of the SERCA2a isoform of the sarcoplasmic reticulum Ca2+-ATPase in skeletal muscle.
    The Biochemical journal, 1999, Jun-15, Volume: 340 ( Pt 3)

    Topics: Aging; Amino Acid Sequence; Animals; Biological Transport; Calcium; Calcium-Transporting ATPases; Cysteine; Endopeptidases; Isoenzymes; Muscle Fibers, Fast-Twitch; Muscle Fibers, Slow-Twitch; Nitrates; Nitric Oxide; Oxygen; Peptide Fragments; Protein Processing, Post-Translational; Rats; Rats, Inbred F344; Sarcoplasmic Reticulum; Sulfhydryl Compounds; Tyrosine

1999
Plasma homocysteine concentrations of preterm infants.
    Biology of the neonate, 1999, Volume: 76, Issue:2

    Topics: Adult; Aging; Cysteine; Female; Gestational Age; Homocysteine; Humans; Infant, Newborn; Infant, Premature; Male; Reference Values

1999
Intrapolypeptide disulfides in human alphaA-crystallin and their effect on chaperone-like function.
    Molecular and cellular biochemistry, 1999, Volume: 199, Issue:1-2

    Topics: Adolescent; Adult; Aged; Aging; Amino Acid Sequence; Child; Crystallins; Cysteine; Disulfides; Glutathione Reductase; Humans; Lens, Crystalline; Mass Spectrometry; Middle Aged; Molecular Chaperones; Molecular Sequence Data; Structure-Activity Relationship

1999
Age-related changes in the cerebral distribution of 99mTc-ECD from infancy to adulthood.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1999, Volume: 40, Issue:11

    Topics: Adolescent; Adult; Aging; Anticonvulsants; Brain; Case-Control Studies; Cerebrovascular Circulation; Child; Child, Preschool; Cysteine; Epilepsy; Female; Gamma Cameras; Humans; Infant; Male; Organotechnetium Compounds; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon

1999
Homocysteine and other thiol compounds in ageing.
    BioFactors (Oxford, England), 2000, Volume: 11, Issue:1-2

    Topics: Adult; Aged; Aged, 80 and over; Aging; Cysteine; Female; Glutathione; Homocysteine; Humans; Male; Sulfhydryl Compounds

2000
Nitric oxide myotoxicity is age related.
    Mechanisms of ageing and development, 2000, Feb-15, Volume: 113, Issue:3

    Topics: Aging; Animals; Creatine Kinase; Cysteine; In Vitro Techniques; Muscle, Skeletal; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Rats; Rats, Inbred F344; S-Nitrosothiols

2000
[Effects of healthy aging on the regional cerebral blood flow measurements using 99mTc-ECD SPECT assessed with statistical parametric mapping].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 2000, Volume: 37, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Cerebrovascular Circulation; Cysteine; Female; Humans; Male; Middle Aged; Organotechnetium Compounds; Tomography, Emission-Computed, Single-Photon

2000
Accumulation of DNA damage in the organs of mice deficient in gamma-glutamyltranspeptidase.
    Mutation research, 2000, Feb-14, Volume: 447, Issue:2

    Topics: Aging; Alkalies; Animals; Chromatography, High Pressure Liquid; Comet Assay; Cysteine; DNA; DNA Damage; gamma-Glutamyltransferase; Glutathione; Homozygote; Kidney; Liver; Lung; Mice; Mutation

2000
Glutathione monoethyl ester protects against glutathione deficiencies due to aging and acetaminophen in mice.
    Mechanisms of ageing and development, 2000, Dec-01, Volume: 120, Issue:1-3

    Topics: Acetaminophen; Aging; Animals; Buthionine Sulfoximine; Cysteine; Glutathione; Kidney Cortex; Liver; Male; Mice; Mice, Inbred C57BL

2000
Polymorphisms at the Werner locus: II. 1074Leu/Phe, 1367Cys/Arg, longevity, and atherosclerosis.
    American journal of medical genetics, 2000, Dec-11, Volume: 95, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aging; Amino Acid Substitution; Arginine; Arteriosclerosis; Coronary Artery Disease; Cysteine; Finland; Gene Frequency; Genotype; Haplotypes; Humans; Infant, Newborn; Leucine; Longevity; Mexico; Middle Aged; Phenylalanine; Polymorphism, Genetic; Werner Syndrome

2000
Ameliorative effect of S-allylcysteine, a major thioallyl constituent in aged garlic extract, on learning deficits in senescence-accelerated mice.
    The Journal of nutrition, 2001, Volume: 131, Issue:3s

    Topics: Aging; Animals; Avoidance Learning; Body Weight; Cysteine; Garlic; Male; Maze Learning; Memory Disorders; Mice; Phytotherapy; Plant Extracts; Plants, Medicinal

2001
Non-invasive methods for absolute cerebral blood flow measurement using 99mTc-ECD: a study in healthy volunteers.
    European journal of nuclear medicine, 2001, Volume: 28, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Aging; Cerebrovascular Circulation; Cross-Sectional Studies; Cysteine; Female; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Organotechnetium Compounds; Prospective Studies; Radionuclide Angiography; Radiopharmaceuticals; Reference Values; Sex Characteristics; Tomography, Emission-Computed, Single-Photon

2001
99mTc-ECD brain perfusion SPET: variability, asymmetry and effects of age and gender in healthy adults.
    European journal of nuclear medicine, 2001, Volume: 28, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Aging; Cerebrovascular Circulation; Cysteine; Female; Humans; Male; Middle Aged; Organotechnetium Compounds; Prospective Studies; Radiopharmaceuticals; Reference Values; Sex Characteristics; Tomography, Emission-Computed, Single-Photon

2001
Brain perfusion SPECT: age- and sex-related effects correlated with voxel-based morphometric findings in healthy adults.
    Radiology, 2001, Volume: 221, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aging; Brain; Cerebrovascular Circulation; Cysteine; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Organotechnetium Compounds; Radiopharmaceuticals; Reference Values; Sex Characteristics; Tomography, Emission-Computed, Single-Photon

2001
Correlates of plasma homocysteine, cysteine and cysteinyl-glycine in respondents in the British National Diet and Nutrition Survey of young people aged 4-18 years, and a comparison with the survey of people aged 65 years and over.
    The British journal of nutrition, 2002, Volume: 87, Issue:1

    Topics: Adolescent; Aged; Aging; Biomarkers; Child; Child, Preschool; Cysteine; Diet Surveys; Dipeptides; Female; Folic Acid; Homocysteine; Humans; Male; Reference Values; Seasons; Sex Factors; Smoking; United Kingdom; Vitamin B 12; Vitamin B 6

2002
Cysteine oxidase activity in rat retina during development.
    Life sciences, 1975, Feb-01, Volume: 16, Issue:3

    Topics: Aging; Amino Acid Oxidoreductases; Animals; Cysteine; Female; Male; Mitochondria; NAD; NADP; Rats; Retina; Sulfinic Acids; Taurine

1975
Studies on cathepsin B in human articular cartilage.
    The Biochemical journal, 1978, Apr-01, Volume: 171, Issue:1

    Topics: Adolescent; Adult; Aged; Aging; Benzoylarginine-2-Naphthylamide; Cartilage, Articular; Cathepsins; Child; Cysteine; Edetic Acid; Humans; In Vitro Techniques; Middle Aged; Osteoarthritis

1978
The effect of age on amino acid composition of human skin collagen.
    Journal of gerontology, 1978, Volume: 33, Issue:4

    Topics: Adult; Age Factors; Aged; Aging; Aldehydes; Amino Acids; Child; Collagen; Cysteine; Female; Humans; Hydroxylysine; Hydroxyproline; Infant, Newborn; Lysine; Middle Aged; Proline; Skin

1978
Mercapturic acid formation in the developing rat.
    Xenobiotica; the fate of foreign compounds in biological systems, 1977, Volume: 7, Issue:11

    Topics: Acetylcysteine; Aging; Animals; Cysteine; Female; Glutathione Transferase; Liver; Male; Propane; Rats; Sulfoxides

1977
Different sensitivites of rat T-lymphocytes on cysteine effects during the response to mitogens.
    Bulletin de l'Academie polonaise des sciences. Serie des sciences biologiques, 1975, Volume: 23, Issue:9

    Topics: Aging; Animals; Cysteine; Lectins; Lymphocyte Activation; Male; Mitogens; Rats; Rats, Inbred Strains; T-Lymphocytes; Thymectomy

1975
Taurine uptake into chick B cells.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1992, Volume: 199, Issue:2

    Topics: Aging; Analysis of Variance; Animals; Animals, Newborn; B-Lymphocytes; beta-Alanine; Biological Transport; Bursa of Fabricius; Chickens; Chromatography, High Pressure Liquid; Cysteine; Dinitrophenols; Neurotransmitter Agents; Ouabain; Sodium; Taurine

1992
Reduced glutathione levels in senile cataractous lens epithelial cells.
    The Tokai journal of experimental and clinical medicine, 1992, Volume: 17, Issue:1

    Topics: Aged; Aged, 80 and over; Aging; Cataract; Cataract Extraction; Chromatography, High Pressure Liquid; Cysteine; Epithelium; Glutathione; Humans; Lens, Crystalline; Middle Aged

1992
Expression of the polymeric immunoglobulin receptor by cultured aged rat hepatocytes.
    Gastroenterology, 1992, Volume: 103, Issue:1

    Topics: Aging; Animals; Cells, Cultured; Cysteine; Enzyme-Linked Immunosorbent Assay; Immunoglobulin A; Liver; Male; Polymers; Rats; Rats, Inbred F344; Receptors, Fc; Receptors, Immunologic; Secretory Component

1992
Acetaminophen-induced depletion of glutathione and cysteine in the aging mouse kidney.
    Biochemical pharmacology, 1992, Jul-07, Volume: 44, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Aging; Animals; Body Weight; Cysteine; Cystine; Dose-Response Relationship, Drug; Glutathione; Kidney; Male; Mice; Mice, Inbred C57BL; Organ Size

1992
Age- and sex-dependent dichlorovinyl cysteine (DCVC) accumulation and toxicity in the mouse kidney: relation to development of organic anion transport and beta-lyase activity.
    Pharmacology & toxicology, 1991, Volume: 68, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Blood Urea Nitrogen; Cysteine; Kidney; Kidney Diseases; Liver; Mice; Mice, Inbred C57BL; Sex Factors

1991
Age-related cysteine uptake as rate-limiting in glutathione synthesis and glutathione half-life in the cultured human lens.
    Experimental eye research, 1991, Volume: 53, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Buthionine Sulfoximine; Child; Child, Preschool; Chromatography, High Pressure Liquid; Cysteine; Glutathione; Half-Life; Humans; Infant; Infant, Newborn; Lens, Crystalline; Methionine Sulfoximine; Middle Aged

1991
Exposure of rat muscle phosphoglycerate kinase to a nonenzymatic MFO system generates the old form of the enzyme.
    Journal of gerontology, 1991, Volume: 46, Issue:6

    Topics: Aging; Animals; Ascorbic Acid; Chlorides; Cysteine; Enzyme Activation; Female; Ferric Compounds; Hot Temperature; Mercaptoethanol; Muscles; Oxidation-Reduction; Phosphoglycerate Kinase; Protein Conformation; Rats; Rats, Inbred Strains; Trypsin

1991
Glutathione augments in vitro proliferative responses of lymphocytes to concanavalin A to a greater degree in old than in young rats.
    The Journal of nutrition, 1990, Volume: 120, Issue:12

    Topics: Aging; Animals; Cell Division; Cells, Cultured; Concanavalin A; Cysteine; Female; Glutathione; Kinetics; Lymphocyte Activation; Lymphocytes; Mercaptoethanol; Rats; Rats, Inbred WF; Receptors, Transferrin; Spleen

1990
The role of protein-thiol mixed disulfides in cataractogenesis.
    Experimental eye research, 1990, Volume: 50, Issue:6

    Topics: Aging; Animals; Cataract; Cysteine; Disulfides; Glutathione; Hydrogen Peroxide; Isoelectric Focusing; Lens, Crystalline; Male; Organ Culture Techniques; Proteins; Rats; Rats, Inbred Strains

1990
O6-methylguanine-DNA methyltransferase levels in tissues of methionine-cysteine deficient subadult and adult mice.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1988, Volume: 91, Issue:2

    Topics: Aging; Animals; Cysteine; Male; Methionine; Methyltransferases; Mice; O(6)-Methylguanine-DNA Methyltransferase; Organ Size

1988
The effect of aging on glutathione and cysteine levels in different regions of the mouse brain.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1989, Volume: 190, Issue:4

    Topics: Aging; Animals; Body Weight; Brain; Brain Stem; Cerebral Cortex; Cysteine; Glutathione; Hippocampus; Male; Mice; Mice, Inbred C57BL; Organ Size

1989
Protection of phosphoglycerate kinase against in vitro aging by selective cysteine methylation.
    The Journal of biological chemistry, 1988, Oct-05, Volume: 263, Issue:28

    Topics: Aging; Animals; Cysteine; Kinetics; Mercaptoethanol; Methylation; Muscle Development; Muscles; Phosphoglycerate Kinase; Rats; Rats, Inbred F344; Reference Values

1988
A decrease in cysteine levels causes the glutathione deficiency of aging in the mosquito.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1988, Volume: 187, Issue:2

    Topics: Aedes; Aging; Animals; Antioxidants; Cysteine; Cystine; Glutathione; Glutathione Disulfide; Thiazoles; Thiazolidines

1988
Depletion of brain glutathione in preweanling mice by L-buthionine sulfoximine.
    Journal of neurochemistry, 1988, Volume: 50, Issue:5

    Topics: Aging; Animals; Antimetabolites; Brain; Buthionine Sulfoximine; Cerebellum; Chromatography, High Pressure Liquid; Cysteine; Glutathione; Liver; Male; Methionine Sulfoximine; Mice; Spinal Cord; Weaning

1988
Transamination of L-cysteine sulfinate in the growing rat.
    Acta medica Okayama, 1987, Volume: 41, Issue:6

    Topics: Aging; Animals; Animals, Newborn; Cysteine; Embryonic and Fetal Development; Female; Fetus; Liver; Neurotransmitter Agents; Placenta; Pregnancy; Rats; Rats, Inbred Strains; Transaminases

1987
Protein synthesis activity in vitro in mouse tissues in relation to methionine-cysteine deficiency and age.
    Mechanisms of ageing and development, 1986, Volume: 34, Issue:3

    Topics: Aging; Animals; Cysteine; DNA; Kidney; Liver; Lung; Male; Methionine; Mice; Polyribosomes; Protein Biosynthesis; RNA, Ribosomal

1986
Methionine-cysteine deficiency and alkylation of DNA in liver, kidney and lung of mice administered dimethylnitrosamine.
    Biochemical pharmacology, 1985, Oct-15, Volume: 34, Issue:20

    Topics: Aging; Alkylation; Animals; Cysteine; Diet; Dimethylnitrosamine; DNA; Kidney; Liver; Lung; Male; Methionine; Methylation; Mice; Purines

1985
Altered heat-lability of a fraction of glutathione reductase in aging human lens.
    The Biochemical journal, 1973, Volume: 134, Issue:4

    Topics: Adult; Aged; Aging; Cysteine; Electrophoresis, Polyacrylamide Gel; Electrophoresis, Starch Gel; Glucosephosphate Dehydrogenase; Glutathione Reductase; Hot Temperature; Humans; Lens, Crystalline; Middle Aged; NADP; Phosphoglycerate Kinase

1973
[Radioactive labeling in the adrenal cortex of the mouse: the problem of steroid sulfation in the inner cortical zones].
    Acta histochemica, 1973, Volume: Suppl 13, Issue:0

    Topics: Adrenal Cortex; Adrenal Glands; Aging; Animals; Autoradiography; Carbon Radioisotopes; Cysteine; Female; Gonadal Steroid Hormones; Isotope Labeling; Male; Mice; Protein Binding; Sulfur Radioisotopes; Time Factors

1973
Alpha-glucan-phosphorylase in the striated muscle of the developing embryo of Gallus domesticus.
    Enzymologia, 1968, Jan-31, Volume: 34, Issue:1

    Topics: Adenine Nucleotides; Aging; Animals; Benzoates; Chick Embryo; Chickens; Cyclic AMP; Cysteine; Glucose; Glucosyltransferases; Mercury; Muscles; Phlorhizin; Pyridoxal Phosphate

1968
Influences on the structural stability of collagen in relation to ageing.
    Gerontologia, 1973, Volume: 19, Issue:3

    Topics: Aging; Animals; Biomechanical Phenomena; Collagen; Connective Tissue; Cysteine; Drug Interactions; Formaldehyde; Methionine; Muscle Contraction; Penicillamine; Perchlorates; Rats; Sodium Chloride; Tail; Tendons

1973
[Study on the relations between the polypeptic amino acids of various organs (liver, spleen, heart, lungs) and the age of the body. Effect of cysteine and folic cysteine on the amino acids].
    Revue de gerontologic d'expression francaise, 1965, Volume: 11, Issue:2

    Topics: Aging; Amino Acids; Animals; Cysteine; Liver; Lung; Myocardium; Rats; Spleen

1965
The colors of the visual pigment chromophores.
    Experimental eye research, 1973, Dec-24, Volume: 17, Issue:6

    Topics: Aging; Animals; Color; Cysteine; Decapodiformes; Hydrogen-Ion Concentration; Methods; Molecular Conformation; Retinal Pigments

1973
Appearance of double mutants in aged cultures of Salmonella typhimurium cysteine-requiring strains.
    Genetics, 1968, Volume: 59, Issue:4

    Topics: Aging; Culture Media; Cysteine; Mutation; Salmonella typhimurium; Transduction, Genetic

1968
Age-relations of cellular growth inhibitors of ketoaldehyde type, in liver and brain of rat.
    Experimental gerontology, 1972, Volume: 7, Issue:1

    Topics: Aging; Aldehydes; Animals; Brain; Brain Chemistry; Cysteine; Growth Substances; Liver; Male; Protein Biosynthesis; Rats; Sulfhydryl Compounds

1972
Cystein-S 35 absorption in old rats.
    Experimental gerontology, 1971, Volume: 6, Issue:5

    Topics: Administration, Oral; Aging; Animals; Ascorbic Acid; Body Weight; Cysteine; Duodenum; Intestinal Absorption; Male; Rats; Sulfur Isotopes

1971
Methionine metabolism in mammals. Regulation of homocysteine methyltransferases in rat tissue.
    Archives of biochemistry and biophysics, 1971, Volume: 146, Issue:1

    Topics: Aging; Alloxan; Animals; Betaine; Chromatography, Gel; Cycloheximide; Cysteine; Dactinomycin; Dietary Proteins; Enzyme Induction; Enzyme Repression; Glucagon; Homocysteine; Hormones; Liver; Male; Methionine; Methyltransferases; Organ Specificity; Rats; Tetrahydrofolates; Ultracentrifugation

1971
Delineation of cystine and cysteine transport systems in rat kidney cortex by developmental patterns.
    Proceedings of the National Academy of Sciences of the United States of America, 1969, Volume: 63, Issue:3

    Topics: Aging; Animals; Animals, Newborn; Biological Transport; Cysteine; Cystine; Electrophoresis; In Vitro Techniques; Kidney; Oxygen; Rats; Sulfur Isotopes; Temperature

1969
[The aging process. The study of cysteine and nucleic acids at the level of the intercellular fractions].
    Giornale di gerontologia, 1969, Volume: 17, Issue:8

    Topics: Aging; Animals; Cell Nucleus; Cysteine; Kidney; Liver; Mitochondria; Mitochondria, Liver; Nucleic Acids; Rats

1969
[Further data on the biochemical findings on the processes of aging].
    Studii si cercetari de fiziologie, 1965, Volume: 10, Issue:2

    Topics: Adult; Aged; Aging; Animals; Cysteine; Glutathione; Humans; Middle Aged; Oxidation-Reduction; Pyridoxine; Rabbits; Rats; Vitamin B 12

1965
Determination of cysteine activated creatine kinase in serum.
    Enzymologia biologica et clinica, 1966, Volume: 7, Issue:4

    Topics: Aging; Child; Child, Preschool; Creatine Kinase; Cysteine; Female; Humans; Infant; Infant, Newborn; Ischemia; Kinetics; Male; Muscle Contraction; Muscular Dystrophies; Physical Exertion

1966