Page last updated: 2024-08-17

cysteamine and Disease Models, Animal

cysteamine has been researched along with Disease Models, Animal in 89 studies

Research

Studies (89)

TimeframeStudies, this research(%)All Research%
pre-199021 (23.60)18.7374
1990's9 (10.11)18.2507
2000's10 (11.24)29.6817
2010's38 (42.70)24.3611
2020's11 (12.36)2.80

Authors

AuthorsStudies
Doulgkeris, CM; Eleftheriou, PT; Galanakis, D; Gavalas, AM; Kourounakis, AP; Kourounakis, PN; Rekka, EA; Tsiakitzis, KC; Victoratos, P1
Braisted, J; Dranchak, P; Earnest, TW; Gu, X; Hoon, MA; Inglese, J; Oliphant, E; Solinski, HJ1
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV1
Albersen, M; Besouw, M; Camps, C; Cyr, D; D'Hauwers, K; de Wever, L; Goffredo, BM; Goossens, E; Hamer, R; Janssen, MCH; Kadam, P; Levtchenko, E; Monnens, L; Reda, A; Rega, LR; Spiessens, C; Taranta, A; van den Heuvel, L; Veys, K; Wetzels, A1
Besouw, M; Reda, A; Veys, K1
Fang, X; Li, W; Ling, S; Liu, X; Luo, Y; Wang, A; Xu, B; Yao, X; Zhang, S; Zhou, Y; Zong, W1
Li, Q; Quan, J; Wang, X; Xu, B; Xu, Z1
Battafarano, G; Bellomo, F; Cairoli, S; Camassei, FD; D'Oria, V; De Leo, E; Del Fattore, A; Emma, F; Goffredo, BM; Pezzullo, M; Polishchuk, E; Polishchuk, R; Raso, R; Rega, LR; Taranta, A1
Aihara, S; Hirashima, Y; Kitazono, T; Nakano, T; Torisu, K1
Ahmad, F; Leake, DS; Mohri, Z; Weinberg, PD; Wen, Y1
D'Souza, RF; Davidson, AJ; Harrison, PT; Hollywood, JA; Holm, TM; Przepiorski, A; Sreebhavan, S; Wolvetang, EJ1
Ambrogini, P; Bartoccini, F; Cesarini, E; Crinelli, R; De Marchis, F; Di Mambro, T; Diotallevi, A; Fraternale, A; Galluzzi, L; Genovese, DA; Green, K; Luchetti, F; Magnani, M; Manuali, E; Pompa, A; Smietana, M; Zara, C1
Choi, SY; Choi, YJ; Eum, WS; Han, KH; Kim, DS; Kim, DW; Lee, KW; Lee, LR; Park, J; Park, JK; Shin, MJ; Song, Y; Yeo, EJ; Yeo, HJ1
Gao, L; Jin, J; Liu, P; Lu, WH; Lv, J; Xie, X; Zhang, H1
Almaguel, FG; Debinski, W; Herpai, DM; Mintz, A; Pandya, DN; Sattiraju, A; Solingapuram Sai, KK; Wadas, TJ; Xuan, A1
Cicchetti, F; David, LS; Lamontagne-Proulx, J; Saint-Pierre, M1
Brinckmann, J; Herold, S; Hitomi, K; Iismaa, SE; Mižíková, I; Morty, RE; Nardiello, C; Pease, RJ; Pfeffer, T; Seeger, W; Silva, DM; Steenbock, H; Surate Solaligue, DE; Tatsukawa, H; Vadász, I1
Cho, SB; Cho, YJ; Choi, SY; Choi, YJ; Eum, WS; Han, KH; Hwang, JS; Jo, HS; Kim, DS; Kim, DW; Kim, HA; Kim, JA; Lee, CH; Lee, KW; Park, J; Park, JH; Shin, MJ; Yeo, EJ; Yeo, HJ; Yong, JI1
Krishnamurthy, S; Kumar, AS; Paliwal, P; Patne, SCU; Singh, SP; Tripathi, H1
Chen, J; Chen, W; Deng, J; He, M; Huang, X; Li, C; Li, Y; Lim, RX; Ma, L; Phan, JB; Wan, F1
Cho, SH; Cho, SW; Choi, SY; Eum, WS; Hwang, HS; Kim, DW; Ku, SK; Kwon, OS; Lee, SH; Park, J; Yoon, GH1
Hahm, KB; Han, YM; Kangwan, N; Kim, EH; Kim, JS; Kim, TS; Kim, YJ; Kwon, O; Park, JM1
Bahrami, NM; Barshop, BA; Duffield, JS; Eddy, AA; Gangoiti, JA; Lopez-Guisa, JM; Okamura, DM; Pasichnyk, K; Ren, S; Williams, JM; Yamaguchi, I1
Ahluwalia, A; Deng, X; Khomenko, T; Patel, KN; Sandor, Z; Szabo, S; Tarnawski, A1
Ahn, EH; Cho, SW; Choi, SY; Eom, SA; Eum, WS; Jo, HS; Kim, DS; Kim, DW; Kim, HR; Kim, SM; Park, J; Shin, MJ; Woo, SJ1
Li, DW; Liu, YL; Sun, BL; Wang, T; Yang, MF; Zhang, JH; Zhang, ZY1
Choi, SY; Hwang, HS; Jung, YO; Kim, DW; Kim, HA; Park, IY1
Badrinarayanan, S; Boivin, L; Bousquet, M; Chabrat, A; Charest, J; Cicchetti, F; Cisbani, G; Drouin-Ouellet, J; Gibrat, C; Lagacé, M; Lavallée-Bourget, MH; Lebel, M; Lévesque, M; Saint-Pierre, M1
Du, F; Fan, D; Ma, L; Tong, C; Wu, Y; Xie, G; Xu, Y; Yu, H1
Bona, G; Buonpensiero, P; De Gregorio, F; De Rosa, G; De Stefano, D; Di Pasqua, A; Esposito, S; Ferrari, E; Grassia, R; Guido, S; Kroemer, G; Leone, CA; Lusa, S; Maiuri, L; Maiuri, MC; Mehta, A; Raia, V; Salvadori, L; Sana, I; Sepe, A; Stoll, G; Tosco, A1
De Spiegeleer, B; Fortin, A; Gauthier, S; Gros, P; Hawari, J; Moradin, N; Stevenson, MM; Tam, M; Torre, S; Vandercruyssen, K1
Bodas, M; Chandramani-Shivalingappa, P; Hole, R; Van Westphal, C; Vij, N1
Choi, SY; Hwang, HS; Kim, HA; Park, IY1
Amagai, M; Ishikawa, H; Jin, L; Kameyama, K; Kawachi, S; Kitagawa, Y; Kitajima, M; Kubota, T; Kumai, K; Nagao, K; Nakamura, T; Saikawa, Y; Sano, K; Shinoda, M; Tanabe, M; Wada, N; Wakabayashi, G; Yoshida, M1
Chan, P; Sun, L; Wang, C; Wu, Y; Xu, S; Zhou, M1
Choi, SE; Choi, YW; Eum, JY; Kang, KH; Kang, MH; Kang, MJ; Lee, MW; Oh, CH; Park, KH; Park, SH1
Jouyban, A; Karimi, I; Saghaei, F; Samini, M1
Cicchetti, F; Gibrat, C1
Asad, M; Asres, K; Engidawork, E; Melese, E1
Ahn, EH; Choi, SY; Eum, WS; Jeong, HJ; Kang, HW; Kim, DW; Kim, MJ; Kim, SY; Kim, TY; Kim, YN; Kwon, HJ; Kwon, SW; Lee, KS; Park, J; Shin, MJ; Sohn, EJ1
Gros, P; Min-Oo, G1
Chen, L; Deng, X; Folkman, J; Khomenko, T; Osapay, K; Sandor, Z; Shiloach, J; Szabo, S; Tolstanova, G; Xiong, X1
Geetha, A; Saranya, P1
Arumugam, G; Karthikeyan, NS; Panneerselvam, S1
Flynn, KJ; Jester, JV; Nien, CJ; Simpson, JL1
Cho, SY; Jeong, EM; Jeong, J; Kim, HJ; Kim, IG; Kim, MK; Lee, HJ; Lee, JH; Lee, SM; Lim, J; Shin, DM; Wee, WR1
Choi, KS; Hahm, KB; Hong, H; Kim, EH; Kim, JH; Lee, JS; Ock, CY1
Fujisawa, T; Gahl, WA; Joshi, BH; Patel, PS; Puri, RK; Rubin, B; Suzuki, A1
Aparecida Severi, J; Bonamin, F; Cássia Santos, R; Hiruma-Lima, CA; Rodrigues Orsi, P; Stasi, LC; Vilegas, W1
Cho, SW; Cho, YS; Choi, SY; Eom, SA; Eum, WS; Hwang, HS; Kim, DS; Kim, DW; Kim, YN; Lee, SH; Park, J; Sohn, EJ; Yoon, GH1
Das, PK; Kar, D; Pillai, S; Pradhan, D; Sahoo, S1
Hobsley, M; Paul Jayaraj, A; Tovey, FI1
Tsai, SJ1
Casabianca, A; Chiarantini, L; Cinatl, J; Clayette, P; Fraternale, A; Magnani, M; Oiry, J; Orlandi, C; Paoletti, MF; Schiavano, GF; Vogel, JU1
Athaydes, GA; Dornelles, PK; Feksa, LR; Fleck, RM; Rech, VC; Rodrigues-Junior, V; Wannmacher, CM1
Gallagher, GT; Horner, HC; Kovacs, K; McComb, DJ; Schwedes, U; Szabo, S; Usadel, KH1
Fisher, EA; Gahl, WA1
Bálint, GA; Náfrádi, J; Varró, V1
Hüttner, I; Kovacs, K; McComb, DJ; Szabo, S1
Wattenberg, LW1
Hosoda, S; Ikedo, H; Saito, T1
Matsuoka, N; Yamaguchi, I; Yamazaki, M1
Duvnjak, M; Grabarevic, Z; Jagic, V; Mise, S; Petek, M; Rotkvic, I; Rucman, R; Seiwerth, S; Sikiric, P; Turkovic, B1
Harding, RK; Krantis, A; McKay, AE; Morris, GP1
Desai, JK; Goyal, RK; Parmar, NS1
Ergun, E; Gürbüz, I; Yeşilada, E1
Dodig, M; Duvnjak, M; Ivankovic, D; Rotkvic, I; Simicevic, VN; Troskot, B1
Cole, L; Congdon, NT; Duncan, DT; Fisher, DT; Hazelwood, DT; McNaughton, C; Pham, T; Rieger, KT; Sanchez, AT; Urist, JT; Vitale, ST; West, ST1
Loiseau, PM; Lubert, P; Wolf, JG1
Cheon, HG; Lee, DH; Lee, SS; Lim, H1
Abraham, BK; Asad, M; Koumaravelou, K; Ramaswamy, S; Shewade, DG; Vasu, S1
Haith, LR; Reynolds, ES; Szabo, S1
Szabo, S1
Japundzic, I; Levi, E; Rakic-Stojiljkovic, L1
Millard, WJ; Romano, TM1
Davis, KL; Haroutunian, V; Santucci, AC1
Iarygin, KN; Krivosheev, OG; Moskovkin, GN; Polonskiĭ, VM; Vinogradov, VA1
Azcarraga, F; Bermúdez, JD; Calvo, MA; Esplugues, J; Lloris, JM; Martí, E; Narbona, B1
Pihan, G; Szabo, S1
Pfeiffer, CJ; Pfeiffer, DC; Szabo, S1
Cahill, MC; Gallagher, GT; Szabo, S1
Miura, Y; Nagamatsu, Y; Ohe, K; Taoka, Y; Yagita, M1
Kuwahara, Y; Okabe, S; Tanaka, H1
Kamogawa, A; Kumasaka, M; Ohta, S; Shinoda, M; Tatsugi, A1
Gallagher, GT; Pihan, G; Szabo, S1
Kirkegaard, P; Olsen, PS; Poulsen, SS1
Andreev, VI; Blagovidov, DF; Kaem, RI; Mirkhodzhaev, IA1
Badalamenti, JN; Lancaster, C; Nezamis, JE; Robert, A1
Selye, H; Szabo, S1

Reviews

5 review(s) available for cysteamine and Disease Models, Animal

ArticleYear
Fertility in Cystinosis.
    Cells, 2021, 12-15, Volume: 10, Issue:12

    Topics: Animals; Biomarkers; Cysteamine; Cystinosis; Disease Models, Animal; Fertility; Humans; Models, Biological

2021
Potential of cystamine and cysteamine in the treatment of neurodegenerative diseases.
    Progress in neuro-psychopharmacology & biological psychiatry, 2011, Mar-30, Volume: 35, Issue:2

    Topics: Animals; Cystamine; Cysteamine; Disease Models, Animal; Enzyme Inhibitors; Humans; Huntington Disease; Mice; Mice, Transgenic; Molecular Targeted Therapy; Neurodegenerative Diseases; Neuroprotective Agents; Parkinson Disease; Radiation-Protective Agents

2011
Genetic analysis in mice identifies cysteamine as a novel partner for artemisinin in the treatment of malaria.
    Mammalian genome : official journal of the International Mammalian Genome Society, 2011, Volume: 22, Issue:7-8

    Topics: Amidohydrolases; Animals; Artemisinins; Cysteamine; Disease Models, Animal; Drug Therapy, Combination; GPI-Linked Proteins; Humans; Malaria; Mice; Plasmodium

2011
Inhibition of chemical carcinogenesis by antioxidants.
    Carcinogenesis; a comprehensive survey, 1980, Volume: 5

    Topics: Animals; Antioxidants; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Carcinogens; Cysteamine; Disease Models, Animal; Disulfiram; Ethoxyquin; Selenium

1980
Development and significance of cysteamine and propionitrile models of duodenal ulcer.
    Chronobiology international, 1987, Volume: 4, Issue:1

    Topics: Animals; Circadian Rhythm; Cysteamine; Disease Models, Animal; Duodenal Ulcer; Gastric Acid; Gastrointestinal Motility; Mice; Nitriles; Rats

1987

Trials

1 trial(s) available for cysteamine and Disease Models, Animal

ArticleYear
A novel treatment of cystic fibrosis acting on-target: cysteamine plus epigallocatechin gallate for the autophagy-dependent rescue of class II-mutated CFTR.
    Cell death and differentiation, 2016, Volume: 23, Issue:8

    Topics: Adolescent; Animals; Autophagy; Biomarkers; Catechin; Child; Cysteamine; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Models, Animal; Drug Therapy, Combination; Homozygote; Humans; Interleukin-8; Lung; Mice; Mice, Knockout; Mutation; Sputum; Tumor Necrosis Factor-alpha

2016

Other Studies

83 other study(ies) available for cysteamine and Disease Models, Animal

ArticleYear
Synthesis and pharmacochemical study of novel polyfunctional molecules combining anti-inflammatory, antioxidant, and hypocholesterolemic properties.
    Bioorganic & medicinal chemistry letters, 2006, Feb-15, Volume: 16, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Antioxidants; Arthritis; Cholesterol; Disease Models, Animal; Drug Design; Drug Evaluation, Preclinical; Female; Inflammation; Pipecolic Acids; Proline; Rats; Rats, Inbred F344; Structure-Activity Relationship; Triglycerides

2006
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
    Science translational medicine, 2019, 07-10, Volume: 11, Issue:500

    Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, Spinal; Humans; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pruritus; Receptors, Atrial Natriuretic Factor; Reproducibility of Results; Signal Transduction; Small Molecule Libraries

2019
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

2020
Human and animal fertility studies in cystinosis reveal signs of obstructive azoospermia, an altered blood-testis barrier and a subtherapeutic effect of cysteamine in testis.
    Journal of inherited metabolic disease, 2021, Volume: 44, Issue:6

    Topics: Adult; Animals; Azoospermia; Blood-Testis Barrier; Cysteamine; Cystine Depleting Agents; Cystinosis; Disease Models, Animal; Extracellular Matrix Proteins; Humans; Infertility, Male; Male; Mice; Mice, Inbred C57BL; Middle Aged; Neoplasm Proteins; Retrospective Studies; Testis; Young Adult; Zonula Occludens-1 Protein

2021
Transglutaminase 3 Attenuates Skin Inflammation in Psoriasis by Inhibiting NF-κB Activation through Phosphorylated STAT3-TET3 Signaling.
    The Journal of investigative dermatology, 2022, Volume: 142, Issue:11

    Topics: Animals; Cysteamine; Cytokines; Dermatitis; Disease Models, Animal; Imiquimod; Inflammation; Keratinocytes; Mice; Mice, Inbred BALB C; NF-kappa B; Psoriasis; RNA, Small Interfering; Skin; STAT3 Transcription Factor; Transglutaminases

2022
N-cystaminylbiguanide MC001 prevents neuron cell death and alleviates motor deficits in the MPTP-model of Parkinson's disease.
    Neuroscience letters, 2022, 07-27, Volume: 784

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cell Death; Cysteamine; Disease Models, Animal; Dopaminergic Neurons; Glutamate-Cysteine Ligase; Mice; Mice, Inbred C57BL; Neurodegenerative Diseases; Neuroprotective Agents; Parkinson Disease; Substantia Nigra

2022
Genistein improves renal disease in a mouse model of nephropathic cystinosis: a comparison study with cysteamine.
    Human molecular genetics, 2023, 03-20, Volume: 32, Issue:7

    Topics: Animals; Cysteamine; Cystine; Cystinosis; Disease Models, Animal; Female; Genistein; Kidney; Kidney Diseases; Mice

2023
Acrolein produced during acute kidney injury promotes tubular cell death.
    Biochemical and biophysical research communications, 2023, 07-23, Volume: 666

    Topics: Acrolein; Acute Kidney Injury; Animals; Cell Death; Cysteamine; Disease Models, Animal; Humans; Hypoxia; Ischemia; Kidney; Mice; Oxygen; Polyamines; Reperfusion Injury; RNA, Messenger

2023
Cysteamine inhibits lysosomal oxidation of low density lipoprotein in human macrophages and reduces atherosclerosis in mice.
    Atherosclerosis, 2019, Volume: 291

    Topics: Animals; Antioxidants; Aorta; Aortic Diseases; Atherosclerosis; Cysteamine; Disease Models, Animal; Female; Foam Cells; Humans; Hydrogen-Ion Concentration; Lipoproteins, LDL; Lysosomes; Mice, Knockout; Oxidation-Reduction; Plaque, Atherosclerotic; Receptors, LDL; Sphingomyelin Phosphodiesterase; THP-1 Cells

2019
Use of Human Induced Pluripotent Stem Cells and Kidney Organoids To Develop a Cysteamine/mTOR Inhibition Combination Therapy for Cystinosis.
    Journal of the American Society of Nephrology : JASN, 2020, Volume: 31, Issue:5

    Topics: Amino Acid Transport Systems, Neutral; Animals; Autophagy; Cell Line; CRISPR-Cas Systems; Cysteamine; Cystine; Cystinosis; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Therapy, Combination; Everolimus; Gene Editing; Heterografts; Humans; Induced Pluripotent Stem Cells; Lysosomes; Mice; Mice, SCID; Organoids; Phenotype; TOR Serine-Threonine Kinases

2020
I-152, a supplier of N-acetyl-cysteine and cysteamine, inhibits immunoglobulin secretion and plasma cell maturation in LP-BM5 murine leukemia retrovirus-infected mice by affecting the unfolded protein response.
    Biochimica et biophysica acta. Molecular basis of disease, 2020, 12-01, Volume: 1866, Issue:12

    Topics: Acetylcysteine; Animals; Antiviral Agents; Cysteamine; Disease Models, Animal; Female; Immunoglobulins; Injections, Intraperitoneal; Leukemia, Experimental; Mice; Mice, Inbred C57BL; Plasma Cells; Protein Unfolding; Retroviridae Infections; Tumor Virus Infections; Unfolded Protein Response

2020
PEP-1-GLRX1 Reduces Dopaminergic Neuronal Cell Loss by Modulating MAPK and Apoptosis Signaling in Parkinson's Disease.
    Molecules (Basel, Switzerland), 2021, Jun-01, Volume: 26, Issue:11

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Cell Line; Cysteamine; Disease Models, Animal; Dopaminergic Neurons; Gene Expression Regulation; Glutaredoxins; Humans; Male; MAP Kinase Signaling System; Mice; Parkinson Disease; Peptides; Substantia Nigra

2021
Propensity of IgA to self-aggregate via tailpiece cysteine-471 and treatment of IgA nephropathy using cysteamine.
    JCI insight, 2021, 10-08, Volume: 6, Issue:19

    Topics: Animals; Cysteamine; Cysteine; Cystine Depleting Agents; Disease Models, Animal; Glomerulonephritis, IGA; Humans; Immunoglobulin A; Immunoglobulin J-Chains; Kidney Glomerulus; Mice; Protein Aggregation, Pathological; Rats

2021
IL13RA2 targeted alpha particle therapy against glioblastomas.
    Oncotarget, 2017, Jun-27, Volume: 8, Issue:26

    Topics: Actinium; Alpha Particles; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Copper Radioisotopes; Cysteamine; Disease Models, Animal; DNA Breaks, Double-Stranded; Gene Expression; Glioblastoma; Humans; Interleukin-13 Receptor alpha2 Subunit; Isotope Labeling; Male; Mice; Peptides; X-Ray Microtomography; Xenograft Model Antitumor Assays

2017
The effects of cysteamine in a mouse model of levodopa-induced dyskinesias.
    Neuroscience letters, 2018, Jan-01, Volume: 662

    Topics: Animals; Cysteamine; Cystine Depleting Agents; Disease Models, Animal; Dopamine Agents; Dyskinesia, Drug-Induced; Levodopa; Mice

2018
Targeting transglutaminase 2 partially restores extracellular matrix structure but not alveolar architecture in experimental bronchopulmonary dysplasia.
    The FEBS journal, 2018, Volume: 285, Issue:16

    Topics: Animals; Bronchopulmonary Dysplasia; Collagen; Cysteamine; Dipeptides; Disease Models, Animal; Extracellular Matrix; Female; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; GTP-Binding Proteins; Hyperoxia; Lung; Mice, Inbred C57BL; Mice, Knockout; Molecular Targeted Therapy; Protein Glutamine gamma Glutamyltransferase 2; Pulmonary Alveoli; Transglutaminases

2018
PEP-1-PEA15 suppresses inflammatory responses by regulation of MAPK in macrophages and animal models.
    Immunobiology, 2018, Volume: 223, Issue:11

    Topics: Animals; Apoptosis Regulatory Proteins; Cysteamine; Cytokines; Disease Models, Animal; DNA Fragmentation; Edema; Extracellular Signal-Regulated MAP Kinases; Humans; Inflammation; Inflammation Mediators; Intracellular Signaling Peptides and Proteins; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred ICR; Peptides; Phosphoproteins; RAW 264.7 Cells; Reactive Oxygen Species; Signal Transduction; Tetradecanoylphorbol Acetate

2018
Pharmacological application of barium containing bioactive glass in gastro-duodenal ulcers.
    Materials science & engineering. C, Materials for biological applications, 2018, Nov-01, Volume: 92

    Topics: Animals; Barium; Barium Compounds; Ceramics; Cysteamine; Disease Models, Animal; Duodenal Ulcer; Male; Oxides; Rats; Rats, Wistar; Stomach Ulcer

2018
Investigation of copper-cysteamine nanoparticles as a new photosensitizer for anti-hepatocellular carcinoma.
    Cancer biology & therapy, 2019, Volume: 20, Issue:6

    Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Copper; Cysteamine; Disease Models, Animal; Dose-Response Relationship, Drug; Exosomes; Humans; Liver Neoplasms; Metal Nanoparticles; Mice; Photosensitizing Agents; Singlet Oxygen; Solubility; Ultraviolet Rays; Xenograft Model Antitumor Assays

2019
Transduced PEP-1-FK506BP ameliorates corneal injury in Botulinum toxin A-induced dry eye mouse model.
    BMB reports, 2013, Volume: 46, Issue:2

    Topics: Administration, Topical; Animals; Botulinum Toxins, Type A; Cell Line; Conjunctiva; Cornea; Cysteamine; Disease Models, Animal; Dry Eye Syndromes; Immunohistochemistry; Interleukin-1beta; Macrophage Inflammatory Proteins; Mice; Peptides; Recombinant Fusion Proteins; Tacrolimus Binding Proteins; Transduction, Genetic; Tumor Necrosis Factor-alpha

2013
Anti-inflammatory and carbonic anhydrase restoring actions of yam powder (Dioscorea spp) contribute to the prevention of cysteamine-induced duodenal ulcer in a rat model.
    Nutrition research (New York, N.Y.), 2013, Volume: 33, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Carbonic Anhydrases; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cysteamine; Cytokines; Dioscorea; Disease Models, Animal; Duodenal Ulcer; Inflammation Mediators; Male; Nitric Oxide Synthase Type II; Pantoprazole; Phytotherapy; Plant Preparations; Plant Tubers; Powders; Rats; Rats, Sprague-Dawley; RNA, Messenger

2013
Cysteamine modulates oxidative stress and blocks myofibroblast activity in CKD.
    Journal of the American Society of Nephrology : JASN, 2014, Volume: 25, Issue:1

    Topics: Actins; Animals; Antioxidants; Cell Differentiation; Cell Line; Cell Proliferation; Cysteamine; Disease Models, Animal; Extracellular Matrix Proteins; Fibrosis; GTP-Binding Proteins; Macrophages; Male; Mice; Mice, Inbred C57BL; Myofibroblasts; Oxidative Stress; Protein Glutamine gamma Glutamyltransferase 2; Rats; Renal Insufficiency, Chronic; RNA, Messenger; Transglutaminases; Ureteral Obstruction

2014
STAT3 and importins are novel mediators of early molecular and cellular responses in experimental duodenal ulceration.
    Digestive diseases and sciences, 2014, Volume: 59, Issue:2

    Topics: Active Transport, Cell Nucleus; alpha Karyopherins; Animals; Apoptosis; beta Karyopherins; Cysteamine; Disease Models, Animal; Duodenal Ulcer; Duodenum; Early Growth Response Protein 1; Epirizole; Female; Gene Expression Regulation; Mice; Mice, Knockout; Oligodeoxyribonucleotides; Phosphorylation; Rats; Rats, Sprague-Dawley; Signal Transduction; STAT3 Transcription Factor; Time Factors; Tyrosine

2014
PEP-1-PEA-15 protects against toxin-induced neuronal damage in a mouse model of Parkinson's disease.
    Biochimica et biophysica acta, 2014, Volume: 1840, Issue:6

    Topics: Animals; Apoptosis Regulatory Proteins; Cysteamine; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Humans; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Parkinson Disease; Peptides; Phosphoproteins; Reactive Oxygen Species; Recombinant Fusion Proteins; Transduction, Genetic

2014
Cysteamine alleviates early brain injury via reducing oxidative stress and apoptosis in a rat experimental subarachnoid hemorrhage model.
    Cellular and molecular neurobiology, 2015, Volume: 35, Issue:4

    Topics: Animals; Apoptosis; Behavior, Animal; Blood-Brain Barrier; Brain Edema; Brain Injuries; Brain-Derived Neurotrophic Factor; Caspase 3; Cerebral Cortex; Cysteamine; Disease Models, Animal; Fluorescent Antibody Technique; In Situ Nick-End Labeling; Male; Oxidative Stress; Permeability; Rats, Sprague-Dawley; Reactive Oxygen Species; Subarachnoid Hemorrhage

2015
PEP-1-FK506BP12 inhibits matrix metalloproteinase expression in human articular chondrocytes and in a mouse carrageenan-induced arthritis model.
    BMB reports, 2015, Volume: 48, Issue:7

    Topics: Animals; Arthritis; Carrageenan; Cartilage, Articular; Cells, Cultured; Chondrocytes; Cysteamine; Disease Models, Animal; Edema; Humans; Interleukin-1beta; Matrix Metalloproteinase 13; Mice; Mitogen-Activated Protein Kinases; NF-kappa B; Peptides; Recombinant Fusion Proteins; Tacrolimus Binding Protein 1A; Transduction, Genetic

2015
Cystamine/cysteamine rescues the dopaminergic system and shows neurorestorative properties in an animal model of Parkinson's disease.
    Neurobiology of disease, 2015, Volume: 82

    Topics: Animals; Antiparkinson Agents; Astrocytes; Cell Line; Cells, Cultured; Corpus Striatum; Cystamine; Cysteamine; Disease Models, Animal; Dopaminergic Neurons; Indans; Lipopolysaccharides; Male; Mice, Inbred C57BL; Neurites; Neuroprotective Agents; Oxidopamine; Parkinsonian Disorders

2015
PEP-1-MsrA ameliorates inflammation and reduces atherosclerosis in apolipoprotein E deficient mice.
    Journal of translational medicine, 2015, Sep-26, Volume: 13

    Topics: Animals; Apolipoproteins E; Apoptosis; Aryldialkylphosphatase; Atherosclerosis; Cell Line; Cysteamine; Disease Models, Animal; Escherichia coli; HeLa Cells; Humans; Inflammation; Liver; Macrophages; Male; Methionine Sulfoxide Reductases; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidation-Reduction; Oxidative Stress; Peptides; Protein Structure, Tertiary; Reactive Oxygen Species; Recombinant Fusion Proteins; Superoxide Dismutase

2015
Cysteamine broadly improves the anti-plasmodial activity of artemisinins against murine blood stage and cerebral malaria.
    Malaria journal, 2016, 05-06, Volume: 15, Issue:1

    Topics: Animals; Antimalarials; Artemisinins; Cell Survival; Cysteamine; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Female; Malaria; Malaria, Cerebral; Mice; Plasmodium berghei; Plasmodium chabaudi; Survival Analysis; Treatment Outcome

2016
Cigarette smoke-induced autophagy impairment accelerates lung aging, COPD-emphysema exacerbations and pathogenesis.
    American journal of physiology. Cell physiology, 2018, 01-01, Volume: 314, Issue:1

    Topics: Animals; Autophagy; Case-Control Studies; Cell Line; Cellular Senescence; Cigarette Smoking; Cysteamine; Cytokines; Disease Models, Animal; Disease Progression; Epithelial Cells; Humans; Inclusion Bodies; Inflammation Mediators; Lung; Mice, Inbred C57BL; Pulmonary Disease, Chronic Obstructive; Pulmonary Emphysema; Sequestosome-1 Protein; Severity of Illness Index; Smoke; Ubiquitination

2018
PEP-1-GRX-1 Modulates Matrix Metalloproteinase-13 and Nitric Oxide Expression of Human Articular Chondrocytes.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2017, Volume: 41, Issue:1

    Topics: Animals; Carrageenan; Cartilage, Articular; Cells, Cultured; Cysteamine; Disease Models, Animal; Down-Regulation; Edema; Glutaredoxins; Humans; Immunohistochemistry; Interleukin-1beta; Lipopolysaccharides; Male; Matrix Metalloproteinase 13; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; NF-kappa B; Nitric Oxide; Peptides; Recombinant Fusion Proteins; Signal Transduction

2017
Candida albicans infection delays duodenal ulcer healing in cysteamine-induced duodenal ulcers in rats.
    Digestive diseases and sciences, 2008, Volume: 53, Issue:11

    Topics: Animals; Candida albicans; Candidiasis; Cysteamine; Disease Models, Animal; Duodenal Ulcer; Duodenum; Male; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar; Time Factors; Vascular Endothelial Growth Factor A; Wound Healing

2008
Effects of cysteamine on MPTP-induced dopaminergic neurodegeneration in mice.
    Brain research, 2010, Jun-04, Volume: 1335

    Topics: Animals; Brain-Derived Neurotrophic Factor; Cysteamine; Disease Models, Animal; Dopamine; Glutathione; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neurons; Neuroprotective Agents; Oxidative Stress; Parkinsonian Disorders; Reactive Oxygen Species; Substantia Nigra; Treatment Outcome

2010
Pep-1 peptide-conjugated elastic liposomal formulation of taxifolin glycoside for the treatment of atopic dermatitis in NC/Nga mice.
    International journal of pharmaceutics, 2010, Dec-15, Volume: 402, Issue:1-2

    Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cysteamine; Dermatitis, Atopic; Disease Models, Animal; Drug Carriers; Elasticity; Excipients; Glucosides; Liposomes; Male; Mice; Mice, Inbred ICR; Peptides; Permeability; Quercetin; Skin Absorption

2010
Effects of captopril on the cysteamine-induced duodenal ulcer in the rat.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2012, Volume: 64, Issue:4

    Topics: Animals; Biomarkers; Captopril; Cysteamine; Disease Models, Animal; Duodenal Ulcer; Duodenum; Free Radical Scavengers; Glutathione Peroxidase; Male; Malondialdehyde; Oxidative Stress; Radiation-Protective Agents; Rats; Rats, Wistar; Superoxide Dismutase

2012
Evaluation of the antipeptic ulcer activity of the leaf extract of Plantago lanceolata L. in rodents.
    Phytotherapy research : PTR, 2011, Volume: 25, Issue:8

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Cysteamine; Disease Models, Animal; Duodenal Ulcer; Ethiopia; Female; Male; Mice; Peptic Ulcer; Plant Extracts; Plant Leaves; Plantago; Rats; Rats, Sprague-Dawley

2011
Transduced PEP-1-FK506BP ameliorates atopic dermatitis in NC/Nga mice.
    The Journal of investigative dermatology, 2011, Volume: 131, Issue:7

    Topics: Animals; Cysteamine; Dermatitis, Atopic; Disease Models, Animal; Immunoglobulin E; Interferon-gamma; MAP Kinase Signaling System; Mice; NF-kappa B; Peptides; Recombinant Fusion Proteins; Tacrolimus Binding Proteins; Tumor Necrosis Factor-alpha

2011
Inappropriate angiogenic response as a novel mechanism of duodenal ulceration and impaired healing.
    Digestive diseases and sciences, 2011, Volume: 56, Issue:10

    Topics: Angiostatins; Animals; Cysteamine; Disease Models, Animal; Duodenal Ulcer; Endostatins; Enzyme Inhibitors; Female; Intestinal Mucosa; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Neovascularization, Pathologic; Nitriles; Rats; Rats, Sprague-Dawley; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Vascular Endothelial Growth Factor A; Wound Healing

2011
Antiulcer activity of Andrographis paniculata (Burm.f.) wall. against cysteamine-induced duodenal ulcer in rats.
    Indian journal of experimental biology, 2011, Volume: 49, Issue:7

    Topics: Andrographis; Animals; Anti-Ulcer Agents; Cysteamine; Disease Models, Animal; Duodenal Ulcer; Intestinal Mucosa; Male; Medicine, Ayurvedic; Plant Components, Aerial; Plant Extracts; Rats; Rats, Wistar

2011
Effect of andrographolide on cysteamine-induced duodenal ulcer in rats.
    Natural product research, 2011, Volume: 25, Issue:16

    Topics: Alkaline Phosphatase; alpha-Glucosidases; Andrographis; Animals; Anti-Ulcer Agents; Cysteamine; Disease Models, Animal; Diterpenes; Duodenal Ulcer; Duodenum; Glutathione; Intestinal Mucosa; Male; Microvilli; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Sucrase

2011
Evaluation of topical cysteamine therapy in the CTNS(-/-) knockout mouse using in vivo confocal microscopy.
    Molecular vision, 2011, Volume: 17

    Topics: Administration, Ophthalmic; Amino Acid Transport Systems, Neutral; Animals; Cornea; Crystallization; Cysteamine; Cystine; Cystinosis; Disease Models, Animal; Humans; Mice; Mice, Knockout; Microscopy, Confocal; Ophthalmic Solutions; Treatment Outcome; Visual Acuity

2011
Cysteamine prevents the development of lens opacity in a rat model of selenite-induced cataract.
    Investigative ophthalmology & visual science, 2012, Mar-15, Volume: 53, Issue:3

    Topics: Animals; Animals, Newborn; Cataract; Cell Line; Cysteamine; Disease Models, Animal; Enzyme Activation; Epithelial Cells; Female; Glutathione; GTP-Binding Proteins; Humans; Lens, Crystalline; Male; Protein Glutamine gamma Glutamyltransferase 2; Radiation-Protective Agents; Rats; Rats, Sprague-Dawley; Sodium Selenite; Transglutaminases

2012
Attenuation of cysteamine-induced duodenal ulcer with Cochinchina momordica seed extract through inhibiting cytoplasmic phospholipase A2/5-lipoxygenase and activating γ-glutamylcysteine synthetase.
    Journal of gastroenterology and hepatology, 2012, Volume: 27 Suppl 3

    Topics: Animals; Anti-Ulcer Agents; Antioxidants; Arachidonate 5-Lipoxygenase; Cell Line; Cyclooxygenase 2; Cysteamine; Disease Models, Animal; Dose-Response Relationship, Drug; Duodenal Ulcer; Duodenum; Enzyme Activation; Enzyme Activators; Gastrins; Glutamate-Cysteine Ligase; Glutathione; Inflammation Mediators; Intestinal Mucosa; Lipoxygenase Inhibitors; Male; Momordica; Oxidation-Reduction; Oxidative Stress; Phospholipases A2, Cytosolic; Plant Extracts; Rats; Rats, Sprague-Dawley; Seeds; Time Factors

2012
Cysteamine suppresses invasion, metastasis and prolongs survival by inhibiting matrix metalloproteinases in a mouse model of human pancreatic cancer.
    PloS one, 2012, Volume: 7, Issue:4

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Survival; Cysteamine; Disease Models, Animal; Enzyme Inhibitors; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Mice; Neoplasm Metastasis; Pancreatic Neoplasms; Tumor Cells, Cultured

2012
Hymenaea stigonocarpa Mart. ex Hayne: a Brazilian medicinal plant with gastric and duodenal anti-ulcer and antidiarrheal effects in experimental rodent models.
    Journal of ethnopharmacology, 2012, Aug-30, Volume: 143, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antidiarrheals; Brazil; Castor Oil; Cysteamine; Diarrhea; Disease Models, Animal; Duodenal Ulcer; Ethanol; Female; Flavonoids; Fruit; Gastric Mucosa; Glutathione; Hymenaea; Intestinal Mucosa; Male; Mice; Mice, Inbred Strains; Nitric Oxide; Peroxidase; Phenols; Phytotherapy; Plant Bark; Plant Extracts; Plant Stems; Plants, Medicinal; Rats; Rats, Wistar; Reperfusion Injury; Stomach Ulcer; Tannins

2012
PEP-1-p18 prevents neuronal cell death by inhibiting oxidative stress and Bax expression.
    BMB reports, 2012, Volume: 45, Issue:9

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cell Line; Cysteamine; Disease Models, Animal; DNA Fragmentation; Dopaminergic Neurons; Genetic Vectors; Humans; Mice; MPTP Poisoning; Oxidative Stress; Parkinson Disease; Peptides

2012
Pharmacological efficacy of argemone mexicana plant extract, against cysteamine-induced duodenal ulceration in rats.
    Indian journal of medical sciences, 2011, Volume: 65, Issue:3

    Topics: Animals; Argemone; Cysteamine; Disease Models, Animal; Duodenal Ulcer; Male; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Treatment Outcome

2011
Duodenal ulcer prevalence: research into the nature of possible protective dietary lipids.
    Phytotherapy research : PTR, 2003, Volume: 17, Issue:4

    Topics: Animals; Anti-Ulcer Agents; Cysteamine; Dietary Fats; Disease Models, Animal; Dolichos; Duodenal Ulcer; Duodenum; Ethanol; Female; Phytotherapy; Plant Extracts; Prevalence; Rats; Rats, Wistar

2003
Cysteamine-related agents could be potential antidepressants through increasing central BDNF levels.
    Medical hypotheses, 2006, Volume: 67, Issue:5

    Topics: Animals; Antidepressive Agents; Brain; Brain-Derived Neurotrophic Factor; Cysteamine; Depressive Disorder, Major; Disease Models, Animal; Humans; Mice

2006
Inhibition of murine AIDS by pro-glutathione (GSH) molecules.
    Antiviral research, 2008, Volume: 77, Issue:2

    Topics: Acetylcysteine; Animals; Anti-HIV Agents; Cell Proliferation; Cysteamine; Disease Models, Animal; DNA, Viral; Female; Glutathione; Hypergammaglobulinemia; Immunoglobulin G; Leukemia Virus, Murine; Lymph Nodes; Lymphocytes; Mice; Mice, Inbred C57BL; Murine Acquired Immunodeficiency Syndrome; Organ Size; Polymerase Chain Reaction; Prodrugs; Spleen

2008
Cysteamine prevents inhibition of thiol-containing enzymes caused by cystine or cystine dimethylester loading in rat brain cortex.
    Metabolic brain disease, 2008, Volume: 23, Issue:2

    Topics: Animals; Antioxidants; Cerebral Cortex; Creatine Kinase; Cysteamine; Cystine; Cystinosis; Disease Models, Animal; Enzyme Inhibitors; Lysosomes; Oxidation-Reduction; Oxidative Stress; Pyruvate Kinase; Rats; Rats, Wistar; Sulfhydryl Compounds

2008
Cysteamine-induced adrenocortical necrosis in rats.
    Experimental and molecular pathology, 1981, Volume: 35, Issue:3

    Topics: Adrenal Cortex Diseases; Adrenal Glands; Adrenal Medulla; Animals; Cysteamine; Disease Models, Animal; Dopamine; Female; Hypophysectomy; Microscopy, Electron; Necrosis; Norepinephrine; Rats; Rats, Inbred Strains; Somatostatin

1981
Cysteamine in treatment of type III hyperlipidaemia?
    Lancet (London, England), 1982, Nov-20, Volume: 2, Issue:8308

    Topics: Animals; Cysteamine; Disease Models, Animal; Humans; Hyperlipoproteinemia Type III; Lipoproteins, VLDL; Receptors, Cell Surface; Receptors, Lipoprotein

1982
The effect of naloxone in different gastroduodenal ulcer models.
    Acta physiologica Hungarica, 1983, Volume: 61, Issue:1-2

    Topics: Animals; Cysteamine; Disease Models, Animal; Female; Gastric Mucosa; Indomethacin; Male; Naloxone; Peptic Ulcer; Rats; Rats, Inbred Strains; Receptors, Opioid; Sex Factors; Stress, Physiological

1983
Adrenocortical hemorrhagic necrosis: the role of catecholamines and retrograde medullary-cell embolism.
    Archives of pathology & laboratory medicine, 1981, Volume: 105, Issue:10

    Topics: Acrylonitrile; Adrenal Cortex Diseases; Adrenal Medulla; Animals; Catecholamines; Cysteamine; Disease Models, Animal; Embolism; Female; Hemorrhage; Humans; Necrosis; Pyrazoles; Rats; Rats, Inbred Strains

1981
Praomys (Mastomys) natalensis: animal model for study of histamine-induced duodenal ulcers.
    Gastroenterology, 1981, Volume: 80, Issue:1

    Topics: Animals; Cimetidine; Cysteamine; Disease Models, Animal; Duodenal Ulcer; Female; Gastrins; Guinea Pigs; Histamine; Male; Mice; Mice, Inbred DBA; Pentagastrin; Rats; Rodentia; Species Specificity; Tetragastrin

1981
Changes in brain somatostatin in memory-deficient rats: comparison with cholinergic markers.
    Neuroscience, 1995, Volume: 66, Issue:3

    Topics: Aging; Animals; Avoidance Learning; Biomarkers; Brain; Cerebral Cortex; Choline O-Acetyltransferase; Cognition; Corpus Striatum; Cysteamine; Dementia; Disease Models, Animal; Hippocampus; Male; Maze Learning; Memory Disorders; Raphe Nuclei; Rats; Rats, Inbred F344; Reference Values; Somatostatin

1995
The beneficial effect of BPC 157, a 15 amino acid peptide BPC fragment, on gastric and duodenal lesions induced by restraint stress, cysteamine and 96% ethanol in rats. A comparative study with H2 receptor antagonists, dopamine promotors and gut peptides.
    Life sciences, 1994, Volume: 54, Issue:5

    Topics: Amino Acid Sequence; Animals; Cysteamine; Disease Models, Animal; Dopamine Agents; Duodenal Ulcer; Ethanol; Female; Gastrointestinal Hormones; Histamine H2 Antagonists; Male; Molecular Sequence Data; Peptide Fragments; Proteins; Rats; Rats, Wistar; Stomach Ulcer; Stress, Physiological

1994
Effects of compound U74500A in animal models of gastric and duodenal ulceration.
    Digestive diseases and sciences, 1993, Volume: 38, Issue:4

    Topics: Analysis of Variance; Animals; Anti-Ulcer Agents; Cysteamine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Duodenal Ulcer; Ethanol; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Intestine, Small; Male; Pregnatrienes; Rats; Rats, Sprague-Dawley; Stomach Ulcer

1993
Gastric and duodenal anti-ulcer activity of SKF 38393, a dopamine D1-receptor agonist in rats.
    The Journal of pharmacy and pharmacology, 1995, Volume: 47, Issue:9

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Anti-Ulcer Agents; Cysteamine; Disease Models, Animal; Dopamine Agonists; Duodenal Ulcer; Female; Immersion; Male; Rats; Rats, Wistar; Receptors, Dopamine D1; Stomach Ulcer

1995
Effects of Cistus laurifolius L. flowers on gastric and duodenal lesions.
    Journal of ethnopharmacology, 1997, Volume: 55, Issue:3

    Topics: Animals; Anti-Ulcer Agents; Cysteamine; Disease Models, Animal; Ethanol; Female; Gastric Acid; Indomethacin; Male; Mice; Organ Size; Peptic Ulcer; Plant Extracts; Rats; Rats, Wistar; Serotonin

1997
The protective effect of zinc sulphate pretreatment against duodenal ulcers in the rat.
    Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 1997, Volume: 10, Issue:4

    Topics: Administration, Oral; Animals; Cysteamine; Disease Models, Animal; Dose-Response Relationship, Drug; Duodenal Ulcer; Duodenum; Female; Injections, Intraperitoneal; Intestinal Absorption; Rats; Rats, Wistar; Spectrophotometry, Atomic; Zinc; Zinc Sulfate

1997
The effect of pantethine and ultraviolet-B radiation on the development of lenticular opacity in the emory mouse.
    Current eye research, 2000, Volume: 20, Issue:1

    Topics: Animals; Cataract; Cysteamine; Disease Models, Animal; Disease Progression; Female; Lens, Crystalline; Male; Mice; Mice, Inbred Strains; Pantetheine; Ultraviolet Rays

2000
Contribution of dithiol ligands to in vitro and in vivo trypanocidal activities of dithiaarsanes and investigation of ligand exchange in an aqueous solution.
    Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:11

    Topics: Animals; Arsenicals; Cysteamine; Dansyl Compounds; Disease Models, Animal; Female; Mice; Parasitic Sensitivity Tests; Structure-Activity Relationship; Sulfhydryl Compounds; Thioctic Acid; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

2000
Pharmacological properties of a newly synthesized H(+)/K(+) ATPase inhibitor, 1-(2-methyl-4-methoxyphenyl)-4-.
    European journal of pharmacology, 2001, Jan-05, Volume: 411, Issue:1-2

    Topics: Animals; Anti-Ulcer Agents; Aspirin; Cysteamine; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethanol; Gastric Acid; Gastric Mucosa; H(+)-K(+)-Exchanging ATPase; Indomethacin; Omeprazole; Perfusion; Proton Pump Inhibitors; Pyrroles; Quinolines; Rats; Rats, Sprague-Dawley; Sodium Hydroxide; Stomach; Stomach Ulcer; Time Factors

2001
Gastric antisecretory and antiulcer activity of oxytocin in rats and guinea pigs.
    Life sciences, 2001, Nov-21, Volume: 70, Issue:1

    Topics: Acetic Acid; Acute Disease; Animals; Anti-Ulcer Agents; Chronic Disease; Cysteamine; Disease Models, Animal; Duodenal Ulcer; Duodenum; Ethanol; Female; Gastric Acid; Gastric Mucosa; Guinea Pigs; Histamine; Indomethacin; Male; Oxytocin; Pylorus; Ranitidine; Rats; Rats, Wistar; Stomach; Stomach Ulcer; Vasotocin

2001
Pathogenesis of duodenal ulceration produced by cysteamine or propionitrile: influence of vagotomy, sympathectomy, histamine depletion, H-2 receptor antagonists and hormones.
    Digestive diseases and sciences, 1979, Volume: 24, Issue:6

    Topics: Adrenalectomy; Animals; Castration; Cimetidine; Cysteamine; Disease Models, Animal; Duodenal Ulcer; Gastric Juice; Guanidines; Histamine; Histamine H2 Antagonists; Hypophysectomy; Metiamide; Nitriles; Rats; Sympathectomy; Thiourea; Thyroidectomy; Vagotomy

1979
Duodenal ulcer disease. Animal model: cysteamine-induced acute and chronic duodenal ulcer in the rat.
    The American journal of pathology, 1978, Volume: 93, Issue:1

    Topics: Acute Disease; Animals; Chronic Disease; Cysteamine; Disease Models, Animal; Duodenal Ulcer; Duodenum; Female; Gastric Juice; Gastrins; Male; Rats

1978
Selective inhibition of duodenal and jejunal villous cell alkaline phosphatase by the duodenal ulcerogen cysteamine.
    Scandinavian journal of gastroenterology, 1991, Volume: 26, Issue:5

    Topics: Alkaline Phosphatase; Animals; Cysteamine; Disease Models, Animal; Duodenal Ulcer; Duodenum; Female; In Vitro Techniques; Injections, Subcutaneous; Jejunum; Kidney; Liver; Microvilli; Organ Specificity; Rats; Rats, Inbred Strains

1991
Comparison of efficacy of cysteamine in depleting prolactin immunoreactivity in different hyperprolactinemic animal models.
    Life sciences, 1991, Volume: 49, Issue:22

    Topics: Analysis of Variance; Animals; Cysteamine; Disease Models, Animal; Female; Hyperprolactinemia; Paraneoplastic Endocrine Syndromes; Pituitary Gland; Pituitary Neoplasms; Prolactin; Rats; Rats, Inbred ACI; Rats, Inbred BUF; Rats, Inbred WF

1991
Implications of multiple transmitter system lesions for cholinomimetic therapy in Alzheimer's disease.
    Progress in brain research, 1990, Volume: 84

    Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Avoidance Learning; Cerebral Cortex; Choline O-Acetyltransferase; Corticotropin-Releasing Hormone; Cysteamine; Disease Models, Animal; Dopamine; Hydroxydopamines; Ibotenic Acid; Male; Norepinephrine; Oxidopamine; Physostigmine; Rats; Rats, Inbred Strains; Reference Values; Serotonin; Somatostatin

1990
[The site (central or peripheral) of the anti-ulcer action of dalargin, a synthetic analog of endogenous opioids in an experimental model of cysteamine-induced duodenal ulcer in rats].
    Biulleten' eksperimental'noi biologii i meditsiny, 1987, Volume: 103, Issue:4

    Topics: Animals; Anti-Ulcer Agents; Brain; Cysteamine; Disease Models, Animal; Duodenal Ulcer; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Injections, Intraventricular; Injections, Subcutaneous; Male; Rats; Rats, Inbred Strains; Receptors, Opioid

1987
[Zinc sulfate in various models of acute experimental ulcer].
    Revista espanola de las enfermedades del aparato digestivo, 1986, Volume: 70, Issue:3

    Topics: Acids; Acute Disease; Animals; Cysteamine; Disease Models, Animal; Pepsin A; Peptic Ulcer; Rats; Rats, Inbred Strains; Stress, Physiological; Sulfates; Zinc; Zinc Sulfate

1986
Development of cysteamine-induced ultrastructural surface changes on duodenal mucosa.
    Laboratory investigation; a journal of technical methods and pathology, 1987, Volume: 56, Issue:4

    Topics: Animals; Cysteamine; Disease Models, Animal; Duodenal Ulcer; Duodenum; Female; Intestinal Mucosa; Microscopy, Electron, Scanning; Microvilli; Rats; Rats, Inbred Strains

1987
Cysteamine induces duodenal ulcer in the mouse.
    Digestion, 1986, Volume: 34, Issue:1

    Topics: Administration, Oral; Animals; Cysteamine; Disease Models, Animal; Drug Administration Schedule; Duodenal Ulcer; Female; Gastric Juice; Injections, Subcutaneous; Mice

1986
[The effect of secretin on the cysteamine induced inhibition of alkaline secretion by the duodenal mucosa].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1986, Volume: 83, Issue:3

    Topics: Animals; Bicarbonates; Cysteamine; Disease Models, Animal; Duodenal Ulcer; Duodenum; Intestinal Mucosa; Male; Rats; Rats, Inbred Strains; Secretin

1986
Augmentation of cysteamine and mepirizole-induced lesions in the rat duodenum and stomach by histamine or indomethacin.
    Japanese journal of pharmacology, 1986, Volume: 41, Issue:4

    Topics: Animals; Cysteamine; Disease Models, Animal; Drug Synergism; Duodenal Ulcer; Epirizole; Histamine; Indomethacin; Male; Pyrazoles; Rats; Stomach Ulcer

1986
[Experimental production of various types of cholestasis and the effect of cysteamine].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1986, Volume: 106, Issue:8

    Topics: Animals; Cholestasis; Cholestasis, Intrahepatic; Cysteamine; Disease Models, Animal; Male; Rats; Rats, Inbred Strains

1986
Biliary and pancreatic secretions influence experimental duodenal ulcer without affecting gastric secretion in the rat.
    Digestive diseases and sciences, 1985, Volume: 30, Issue:3

    Topics: Animals; Bile; Common Bile Duct; Cysteamine; Disease Models, Animal; Duodenal Ulcer; Female; Gastric Acid; Gastric Juice; Ligation; Pancreatic Juice; Pepsin A; Pylorus; Rats; Rats, Inbred Strains; Taurocholic Acid

1985
Healing of cysteamine-induced duodenal ulcers in the rat.
    Digestive diseases and sciences, 1985, Volume: 30, Issue:2

    Topics: Animals; Brunner Glands; Cysteamine; Disease Models, Animal; Duodenal Ulcer; Duodenum; Epithelium; Female; Intestinal Mucosa; Rats; Rats, Inbred Strains; Regeneration; Time Factors

1985
[Adenylate cyclase activity of the gastric mucosa and the morphological changes in the gastrointestinal tract in the experimental reproduction of duodenal ulcers with subsequent truncal vagotomy].
    Biulleten' eksperimental'noi biologii i meditsiny, 1985, Volume: 100, Issue:8

    Topics: Adenylyl Cyclases; Animals; Cysteamine; Digestive System; Disease Models, Animal; Duodenal Ulcer; Gastric Mucosa; Histocytochemistry; Male; Rats; Vagotomy

1985
Cysteamine-induced duodenal ulcers: a new model to test antiulcer agents.
    Digestion, 1974, Volume: 11, Issue:3-4

    Topics: Adrenocorticotropic Hormone; Animals; Antacids; Cysteamine; Desoxycorticosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Duodenal Ulcer; Fasting; Female; Gastric Juice; Ligation; Male; Prednisolone; Prostaglandins; Pylorus; Rats; Scopolamine Derivatives; Secretory Rate; Sex Factors; Stimulation, Chemical; Time Factors

1974
Experimental model for production of perforating duodenal ulcers by cysteamine in the rat.
    Nature, 1973, Aug-17, Volume: 244, Issue:5416

    Topics: Administration, Oral; Animals; Cysteamine; Disease Models, Animal; Duodenal Ulcer; Female; Injections, Subcutaneous; Peptic Ulcer Perforation; Rats

1973