Page last updated: 2024-10-25

cystamine and Melanoma

cystamine has been researched along with Melanoma in 6 studies

Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)

Research Excerpts

ExcerptRelevanceReference
"In studies to determine whether pigmentation can be regulated physiologically by thiols, human melanoma cells (MM418c5) and melanocytes were found to become depigmented when cultured continuously in 50 microM cystamine."7.70Inhibition of melanin synthesis by cystamine in human melanoma cells. ( Gardiner, B; Kay, G; Parsons, PG; Qiu, L; Sturm, RA; Tonks, I; Zhang, M, 2000)
"In studies to determine whether pigmentation can be regulated physiologically by thiols, human melanoma cells (MM418c5) and melanocytes were found to become depigmented when cultured continuously in 50 microM cystamine."3.70Inhibition of melanin synthesis by cystamine in human melanoma cells. ( Gardiner, B; Kay, G; Parsons, PG; Qiu, L; Sturm, RA; Tonks, I; Zhang, M, 2000)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's4 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Takada, T1
Yamashita, T2
Sato, M1
Sato, A1
Ono, I1
Tamura, Y1
Sato, N1
Miyamoto, A1
Ito, A1
Honda, H1
Wakamatsu, K1
Ito, S1
Jimbow, K3
Hwang, JS1
Choi, H1
Rho, HS1
Shin, HJ1
Kim, DH1
Lee, J1
Lee, BG1
Chang, I1
Bolognia, JL1
Sodi, SA1
Osber, MP1
Pawelek, JM1
Thomas, PD2
Kishi, H1
Cao, H1
Ota, M2
Singh, S1
Qiu, L1
Zhang, M1
Sturm, RA1
Gardiner, B1
Tonks, I1
Kay, G1
Parsons, PG1
Gili, A1

Other Studies

6 other studies available for cystamine and Melanoma

ArticleYear
Growth inhibition of re-challenge B16 melanoma transplant by conjugates of melanogenesis substrate and magnetite nanoparticles as the basis for developing melanoma-targeted chemo-thermo-immunotherapy.
    Journal of biomedicine & biotechnology, 2009, Volume: 2009

    Topics: Animals; Cystamine; Female; Ferrosoferric Oxide; Free Radicals; Hot Temperature; Immunotherapy; Mela

2009
Pigment-lightening effect of N,N'-dilinoleylcystamine on human melanoma cells.
    The British journal of dermatology, 2004, Volume: 150, Issue:1

    Topics: Blotting, Western; Cystamine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Image Pro

2004
Enhancement of the depigmenting effect of hydroquinone by cystamine and buthionine sulfoximine.
    The British journal of dermatology, 1995, Volume: 133, Issue:3

    Topics: Animals; Buthionine Sulfoximine; Cystamine; Drug Combinations; Drug Synergism; Enzyme Inhibitors; Gu

1995
Selective incorporation and specific cytocidal effect as the cellular basis for the antimelanoma action of sulphur containing tyrosine analogs.
    The Journal of investigative dermatology, 1999, Volume: 113, Issue:6

    Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Division; Cell Line; Cystamine; Cysteamine; DNA; Do

1999
Inhibition of melanin synthesis by cystamine in human melanoma cells.
    The Journal of investigative dermatology, 2000, Volume: 114, Issue:1

    Topics: Cystamine; HeLa Cells; Humans; Melanins; Melanocytes; Melanoma; Monophenol Monooxygenase; Pigmentati

2000
Comparison of in vitro cytotoxicity of N-acetyl and N-propionyl derivatives of phenolic thioether amines in melanoma and neuroblastoma cells and the relationship to tyrosinase and tyrosine hydroxylase enzyme activity.
    Melanoma research, 2000, Volume: 10, Issue:1

    Topics: Amides; Antineoplastic Agents; Cell Division; Cystamine; Cysteamine; Growth Inhibitors; HeLa Cells;

2000