cystamine has been researched along with Cystic Fibrosis of Pancreas in 5 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Restoration of BECN1/Beclin 1-dependent autophagy and depletion of SQSTM1/p62 by genetic manipulation or autophagy-stimulatory proteostasis regulators, such as cystamine, have positive effects on mouse models of human cystic fibrosis (CF)." | 5.19 | Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation. ( Bona, G; Bossi, A; De Gregorio, F; De Rosa, G; De Stefano, D; Esposito, S; Grassia, R; Guido, S; Kroemer, G; Leone, CA; Maiuri, L; Maiuri, MC; Mehta, A; Pettoello-Mantovani, M; Pinna, LA; Raia, V; Salvadori, L; Sepe, A; Tosco, A; Venerando, A; Villella, VR; Zolin, A, 2014) |
| "Cystamine pre-treatment restored ΔF508-CFTR response to the CFTR potentiators genistein, Vrx-532 or Vrx-770 in freshly isolated brushed nasal epithelial cells from ΔF508-CFTR homozygous patients." | 1.38 | Targeting autophagy as a novel strategy for facilitating the therapeutic action of potentiators on ΔF508 cystic fibrosis transmembrane conductance regulator. ( Carnuccio, R; De Matteis, A; Esposito, S; Gavina, M; Guido, S; Kroemer, G; Luciani, A; Luini, A; Maiuri, L; Maiuri, MC; Pettoello-Mantovani, M; Raia, V; Russo, I; Scholte, B; Silano, M; Villella, VR, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Faraj, J | 1 |
| Bodas, M | 1 |
| Pehote, G | 1 |
| Swanson, D | 1 |
| Sharma, A | 1 |
| Vij, N | 1 |
| Villella, VR | 4 |
| Esposito, S | 4 |
| Maiuri, MC | 3 |
| Raia, V | 4 |
| Kroemer, G | 3 |
| Maiuri, L | 4 |
| De Stefano, D | 1 |
| Tosco, A | 1 |
| Sepe, A | 1 |
| De Gregorio, F | 1 |
| Salvadori, L | 1 |
| Grassia, R | 1 |
| Leone, CA | 1 |
| De Rosa, G | 1 |
| Pettoello-Mantovani, M | 3 |
| Guido, S | 3 |
| Bossi, A | 1 |
| Zolin, A | 1 |
| Venerando, A | 1 |
| Pinna, LA | 1 |
| Mehta, A | 1 |
| Bona, G | 1 |
| Luciani, A | 2 |
| Brunetti-Pierri, N | 1 |
| Medina, D | 1 |
| Settembre, C | 1 |
| Gavina, M | 2 |
| Pulze, L | 1 |
| Giardino, I | 1 |
| D'Apolito, M | 1 |
| Masliah, E | 1 |
| Spencer, B | 1 |
| Quaratino, S | 1 |
| Ballabio, A | 1 |
| Russo, I | 1 |
| Silano, M | 1 |
| Carnuccio, R | 1 |
| Scholte, B | 1 |
| De Matteis, A | 1 |
| Luini, A | 1 |
1 trial available for cystamine and Cystic Fibrosis of Pancreas
| Article | Year |
|---|---|
Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation.
Topics: Adaptor Proteins, Signal Transducing; Administration, Oral; Adolescent; Adult; Animals; Apoptosis Re | 2014 |
4 other studies available for cystamine and Cystic Fibrosis of Pancreas
| Article | Year |
|---|---|
Novel cystamine-core dendrimer-formulation rescues ΔF508-CFTR and inhibits Pseudomonas aeruginosa infection by augmenting autophagy.
Topics: Animals; Anti-Bacterial Agents; Autophagy; Biofilms; Cell Membrane; Cystamine; Cystic Fibrosis; Cyst | 2019 |
Towards a rational combination therapy of cystic fibrosis: How cystamine restores the stability of mutant CFTR.
Topics: Animals; Cystamine; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Drug Thera | 2013 |
Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition.
Topics: Acetylcysteine; Adaptor Proteins, Signal Transducing; Adolescent; Adult; Animals; Antioxidants; Apop | 2010 |
Targeting autophagy as a novel strategy for facilitating the therapeutic action of potentiators on ΔF508 cystic fibrosis transmembrane conductance regulator.
Topics: Adaptor Proteins, Signal Transducing; Adolescent; Animals; Antioxidants; Apoptosis Regulatory Protei | 2012 |