cys(11)-cys(15)-endothelin-1-(11-21) has been researched along with Glioma* in 1 studies
1 other study(ies) available for cys(11)-cys(15)-endothelin-1-(11-21) and Glioma
Article | Year |
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A new endothelin C-terminal analogue IBDP 064 antagonizes endothelin-3-induced cell proliferation.
A series of C-terminal linear endothelin analogues were prepared and their activities in C6 rat glioma cell line were tested. Among the synthetic analogues, IBDP 064, Fmoc-Leu-Asp-Ile-Ile-Trp-OH, was the most potent and selective inhibitor of endothelin-3-induced cell proliferation. Its action was comparable with that of the previously described peptide IRL 1038, [Cys11-Cys15]-ET-1(11-21), an ETB specific inhibitor. Topics: Amino Acid Sequence; Animals; Blood Proteins; Cell Division; Endothelin Receptor Antagonists; Endothelins; Fluorenes; Glioma; Molecular Sequence Data; Oligopeptides; Peptide Fragments; Rats; Receptors, Endothelin; Tumor Cells, Cultured | 1995 |