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cyproterone acetate and Cancer of Liver

cyproterone acetate has been researched along with Cancer of Liver in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19904 (15.38)18.7374
1990's16 (61.54)18.2507
2000's6 (23.08)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Reimann, R; Schweinfurth, H; Wolff, T1
Gerner, C; Grasl-Kraupp, B; Hufnagl, K; Kandioler-Eckersberger, D; Klimpfinger, M; Parzefall, W; Schausberger, E; Schulte-Hermann, R; Wrba, F1
Ohde, G; Schulte-Hermann, R; Schuppler, J; Timmermann-Trosiener, I1
Dammé, J; Schulte-Hermann, R; Schuppler, J1
Makino, Y; Nagasue, N; Nakamura, T; Yu, L1
Hammerstein, J; Rabe, T; Runnebaum, B1
Feldmann, K; Grunwald, K; Rabe, T; Runnebaum, B1
Beckmann, J; Queisser, W; Rüdiger, T1
Bursch, W; Grasl-Kraupp, B; Lauer, B; Ruttkay-Nedecky, B; Schulte-Hermann, R; Wagner, A1
Culine, S; Droz, JP; Elias, D; Kattan, J; Spatz, A; Terrier-Lacombe, MJ1
Feldmann, K; Heinemann, L; Rabe, T; Runnebaum, B1
Kohno, H; Kubota, H; Nagasue, N; Tachibana, M; Yamaguchi, M; Yu, L1
Schwarz, LR; Wolff, T1
Berges, RR; Hinkel, A; Pannek, J; Schulze, H; Senge, T1
Roberts, RA1
Cui, Y; Fujimoto, M; Matsuo, Y; Tachibana, K; Tanae, A; Tanaka, T; Watanabe, S; Yamasaki, S1
Deml, E; Favor, J; Krebs, O; Oesterle, D; Schäfer, B; Sund, M; Wolff, T1
de Voogt, H; Denis, L; Sylvester, RJ1
Grasl-Kraupp, B; Hufnagl, K; Löw-Baselli, A; Parzefall, W; Schulte-Hermann, R1
Regidor, M; Regidor, PA; Schindler, EM; Speer, K1
Bonnotte, B; Chauffert, B; Gresset, AC; Lenfant, L; Lorcerie, B; Manfredi, S1
Kasper, P1
Gaer, JA; Keane, PF; Ohri, SK1
Forbes, A; Iqbal, MJ; Johnson, PJ; Wilkinson, ML; Williams, R1
Schlumberger, JF1

Reviews

5 review(s) available for cyproterone acetate and Cancer of Liver

ArticleYear
[Liver tumors in women using oral hormonal contraceptives].
    Zentralblatt fur Gynakologie, 1995, Volume: 117, Issue:3

    Topics: Adenoma, Liver Cell; Carcinoma, Hepatocellular; Contraceptives, Oral, Hormonal; Cyproterone Acetate; Female; Humans; Hyperplasia; Liver; Liver Neoplasms; Product Surveillance, Postmarketing; Risk Factors

1995
Hepatocellular carcinoma during hormonotherapy for prostatic cancer.
    American journal of clinical oncology, 1994, Volume: 17, Issue:5

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cyproterone Acetate; Humans; Liver Neoplasms; Male; Neoplasms, Second Primary; Prostatic Neoplasms; Triptorelin Pamoate

1994
Cyproterone acetate: is it hepato- or genotoxic?
    Drug safety, 1996, Volume: 14, Issue:1

    Topics: Androgen Antagonists; Animals; Carcinoma, Hepatocellular; Cyproterone Acetate; Cytochrome P-450 Enzyme System; DNA; DNA Adducts; DNA Repair; Humans; In Vitro Techniques; Liver; Liver Neoplasms; Rats

1996
Non-genotoxic hepatocarcinogenesis: suppression of apoptosis by peroxisome proliferators.
    Annals of the New York Academy of Sciences, 1996, Dec-27, Volume: 804

    Topics: Animals; Anticholesteremic Agents; Apoptosis; Calcium; Cyproterone Acetate; DNA; DNA Fragmentation; Inositol Phosphates; Liver Neoplasms; Liver Neoplasms, Experimental; Nafenopin; Protein Kinase C; Pyrimidines; S Phase

1996
Cyproterone acetate: a genotoxic carcinogen?
    Pharmacology & toxicology, 2001, Volume: 88, Issue:5

    Topics: Androgen Antagonists; Animals; Antineoplastic Agents; Carcinogenicity Tests; Carcinogens; Cyproterone Acetate; DNA Damage; DNA Repair; Female; Liver Neoplasms; Male; Mutagenicity Tests; Mutagens; Mutation; Risk Assessment; Sex Factors; Tumor Cells, Cultured

2001

Trials

2 trial(s) available for cyproterone acetate and Cancer of Liver

ArticleYear
The importance of prognostic factors in the interpretation of two EORTC metastatic prostate cancer trials. European Organization for Research and Treatment of Cancer (EORTC) Genito-Urinary Tract Cancer Cooperative Group.
    European urology, 1998, Volume: 33, Issue:2

    Topics: Aged; Analysis of Variance; Androgen Antagonists; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Buserelin; Combined Modality Therapy; Cyproterone Acetate; Disease-Free Survival; Flutamide; Goserelin; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Multivariate Analysis; Neoplasm Staging; Orchiectomy; Prognosis; Proportional Hazards Models; Prostatic Neoplasms; Risk Assessment; Survival Rate

1998
[Long-term side-effects following cyproterone acetate containing therapy in gynecology].
    Zentralblatt fur Gynakologie, 2000, Volume: 122, Issue:5

    Topics: Adult; Androgen Antagonists; Carcinoma, Hepatocellular; Cyproterone Acetate; Dose-Response Relationship, Drug; Drug Combinations; Ethinyl Estradiol; Female; Follow-Up Studies; Hirsutism; Humans; Liver Neoplasms; Risk Factors

2000

Other Studies

19 other study(ies) available for cyproterone acetate and Cancer of Liver

ArticleYear
Valuable scientific contributions of Brambilla and Martelli.
    Mutation research, 2004, Volume: 566, Issue:3

    Topics: Animals; Carcinogens; Cyproterone Acetate; Humans; Liver Neoplasms; Mutagens; Progesterone Congeners; Structure-Activity Relationship

2004
Inherent growth advantage of (pre)malignant hepatocytes associated with nuclear translocation of pro-transforming growth factor alpha.
    British journal of cancer, 2004, Nov-29, Volume: 91, Issue:11

    Topics: Animals; Antineoplastic Agents; Cell Nucleus; Cyproterone Acetate; DNA; DNA Replication; Glutathione Transferase; Hepatocytes; Liver Neoplasms; Male; Precancerous Conditions; Protein Transport; Rats; Rats, Wistar; Transforming Growth Factor alpha; Transforming Growth Factor beta; Transforming Growth Factor beta1

2004
Effect of tumor promoters on proliferation of putative preneoplastic cells in rat liver.
    Carcinogenesis; a comprehensive survey, 1982, Volume: 7

    Topics: Animals; Carcinogens; Cell Division; Cyproterone; Cyproterone Acetate; Eating; Female; Hexachlorocyclohexane; Liver; Liver Neoplasms; Male; Mitotic Index; Nitrosamines; Precancerous Conditions; Progesterone; Rats; Rats, Inbred Strains

1982
Assay of some endogenous and synthetic sex steroids for tumor-initiating activity in rat liver using the Solt-Farber system.
    Carcinogenesis, 1983, Volume: 4, Issue:2

    Topics: Androgen Antagonists; Animals; Carcinogens; Cyproterone; Cyproterone Acetate; Estradiol; Ethinyl Estradiol; Liver Neoplasms; Male; Neoplasms, Experimental; Norethindrone; Norethindrone Acetate; Norethynodrel; Progesterone; Rats; Rats, Inbred F344

1983
Effect of androgens and their manipulation on cell growth and androgen receptor (AR) levels in AR-positive and -negative human hepatocellular carcinomas.
    Journal of hepatology, 1995, Volume: 22, Issue:3

    Topics: Carcinoma, Hepatocellular; Cell Division; Cyproterone Acetate; Dihydrotestosterone; Humans; Liver Neoplasms; Receptors, Androgen; Receptors, Cytoplasmic and Nuclear; Testosterone; Tumor Cells, Cultured

1995
[Position of the German Society of Gynecology and Obstetrics on the intended recall of approved CPA-containing drugs].
    Gynakologisch-geburtshilfliche Rundschau, 1995, Volume: 35, Issue:1

    Topics: Carcinoma, Hepatocellular; Cyproterone Acetate; Drug Approval; Female; Germany; Humans; Liver Neoplasms; Product Surveillance, Postmarketing; Societies, Medical

1995
Hepatocellular carcinoma after treatment with cyproterone acetate combined with ethinyloestradiol.
    Lancet (London, England), 1995, Feb-18, Volume: 345, Issue:8947

    Topics: Carcinoma, Hepatocellular; Contraceptives, Oral, Combined; Cyproterone Acetate; Female; Humans; Liver Neoplasms; Middle Aged

1995
Food restriction eliminates preneoplastic cells through apoptosis and antagonizes carcinogenesis in rat liver.
    Proceedings of the National Academy of Sciences of the United States of America, 1994, Oct-11, Volume: 91, Issue:21

    Topics: Animals; Apoptosis; Biomarkers, Tumor; Cell Division; Circadian Rhythm; Cyproterone Acetate; Diet, Reducing; DNA Replication; Fasting; Glutathione Transferase; Liver; Liver Neoplasms; Nafenopin; Precancerous Conditions; Rats; Rats, Wistar; Time Factors

1994
Inhibition of growth and induction of TGF-beta 1 in human hepatocellular carcinoma with androgen receptor by cyproterone acetate in male nude mice.
    Journal of hepatology, 1996, Volume: 25, Issue:4

    Topics: Androgen Antagonists; Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Division; Cyproterone Acetate; DNA, Neoplasm; Humans; Immunohistochemistry; Injections, Subcutaneous; Liver Neoplasms; Male; Mice; Mice, Nude; Middle Aged; Neoplasm Transplantation; Organ Size; Proliferating Cell Nuclear Antigen; Receptors, Androgen; Testis; Transforming Growth Factor beta; Tumor Cells, Cultured

1996
Gender bender.
    Human & experimental toxicology, 1995, Volume: 14, Issue:12

    Topics: Animals; Carcinogens; Cells, Cultured; Cyproterone Acetate; DNA Adducts; DNA Repair; Female; Humans; Liver; Liver Neoplasms; Male; Mutagens; Rats; Sex Characteristics

1995
Cyproterone acetate in the treatment of advanced prostatic cancer: retrospective analysis of liver toxicity in the long-term follow-up of 89 patients.
    European urology, 1996, Volume: 30, Issue:4

    Topics: Aged; Aged, 80 and over; Alkaline Phosphatase; alpha-Fetoproteins; Androgen Antagonists; Antineoplastic Agents; Cyproterone Acetate; Follow-Up Studies; gamma-Glutamyltransferase; Humans; L-Lactate Dehydrogenase; Liver; Liver Neoplasms; Male; Middle Aged; Organ Size; Prostate-Specific Antigen; Prostatic Neoplasms; Retrospective Studies; Transaminases; Treatment Outcome

1996
Follow-up study of children with precocious puberty treated with cyproterone acetate. Ad hoc Committee for CPA.
    Journal of epidemiology, 1997, Volume: 7, Issue:3

    Topics: Adenoma, Liver Cell; Adolescent; Androgen Antagonists; Carcinoma, Hepatocellular; Child; Child, Preschool; Cyproterone Acetate; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Liver Neoplasms; Male; Progesterone Congeners; Puberty, Precocious; Risk

1997
Oral contraceptives and liver cancer. Results of the Multicentre International Liver Tumor Study (MILTS).
    Contraception, 1997, Volume: 56, Issue:5

    Topics: Adult; Age Factors; Carcinoma, Hepatocellular; Case-Control Studies; Contraceptives, Oral; Cyproterone Acetate; Female; Hepatitis B; Hepatitis C; Humans; Liver Cirrhosis; Liver Neoplasms; Middle Aged; Odds Ratio; Risk Factors; Time Factors

1997
The DNA damaging drug cyproterone acetate causes gene mutations and induces glutathione-S-transferase P in the liver of female Big Blue transgenic F344 rats.
    Carcinogenesis, 1998, Volume: 19, Issue:2

    Topics: Animals; Animals, Genetically Modified; Cyproterone Acetate; DNA Adducts; Dose-Response Relationship, Drug; Enzyme Induction; Female; Glutathione Transferase; Liver; Liver Neoplasms; Mutagenicity Tests; Mutagens; Precancerous Conditions; Rats; Rats, Inbred F344

1998
Initiated rat hepatocytes in primary culture: a novel tool to study alterations in growth control during the first stage of carcinogenesis.
    Carcinogenesis, 2000, Volume: 21, Issue:1

    Topics: Animals; Cell Division; Cells, Cultured; Cyproterone Acetate; DNA; Glutathione Transferase; Liver; Liver Neoplasms; Male; Nitrosamines; Phenobarbital; Phenotype; Precancerous Conditions; Rats; Rats, Wistar; Transforming Growth Factor beta

2000
[Hepatocellular carcinoma in a healthy liver possibly due to long-term use of cyproterone acetate].
    Presse medicale (Paris, France : 1983), 2000, Nov-25, Volume: 29, Issue:36

    Topics: Aged; Aged, 80 and over; Androgen Antagonists; Carcinoma, Hepatocellular; Cyproterone Acetate; Drug Administration Schedule; Humans; Liver Neoplasms; Male; Time Factors

2000
Hepatocellular carcinoma and treatment with cyproterone acetate.
    British journal of urology, 1991, Volume: 67, Issue:2

    Topics: Aged; Antineoplastic Agents; Carcinoma, Hepatocellular; Cyproterone; Cyproterone Acetate; Humans; Liver Neoplasms; Male; Prostatic Neoplasms

1991
Response to cyproterone acetate treatment in primary hepatocellular carcinoma is related to fall in free 5 alpha-dihydrotestosterone.
    European journal of cancer & clinical oncology, 1987, Volume: 23, Issue:11

    Topics: Adult; Aged; Androgen Antagonists; Antineoplastic Agents; Carcinoma, Hepatocellular; Cyproterone; Cyproterone Acetate; Dihydrotestosterone; Female; Gonadal Steroid Hormones; Humans; Liver Neoplasms; Male; Middle Aged; Neoplasms, Hormone-Dependent

1987
[Apropos of a letter by Mal et al.: Treatment of 25 patients with hepatocellular carcinoma with an antiandrogen, cyproterone acetate (Androcur)].
    Gastroenterologie clinique et biologique, 1987, Volume: 11, Issue:11

    Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cyproterone; Cyproterone Acetate; Humans; Liver Neoplasms

1987