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cyproheptadine and Tremor

cyproheptadine has been researched along with Tremor in 8 studies

Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.

Tremor: Cyclical movement of a body part that can represent either a physiologic process or a manifestation of disease. Intention or action tremor, a common manifestation of CEREBELLAR DISEASES, is aggravated by movement. In contrast, resting tremor is maximal when there is no attempt at voluntary movement, and occurs as a relatively frequent manifestation of PARKINSON DISEASE.

Research Excerpts

ExcerptRelevanceReference
"We investigated the effects of various serotoninergic drugs and serotonin (5-HT) depletion on physostigmine-induced visible tremor in rats."7.70Effects of serotoninergic drugs on tremor induced by physostigmine in rats. ( Mohanakumar, KP; Muralikrishnan, D; Sarkar, S; Thomas, B, 2000)
"Studies were performed to bring out a serotoninergic involvement in physostigmine tremor, hitherto known to be working via the cholinergic system."7.68Tremorogenesis by physostigmine is unrelated to acetylcholinesterase inhibition: evidence for serotoninergic involvement. ( Ganguly, DK; Mitra, N; Mohanakumar, KP, 1990)
"Clonidine exhibited a dose-dependent protection against harmine-induced tremors in mice."7.67Modification by clonidine of harmine-induced tremors in mice: involvement of serotoninergic system. ( Garg, SK; Kulkarni, SK; Shukla, VK, 1986)
"We investigated the effects of various serotoninergic drugs and serotonin (5-HT) depletion on physostigmine-induced visible tremor in rats."3.70Effects of serotoninergic drugs on tremor induced by physostigmine in rats. ( Mohanakumar, KP; Muralikrishnan, D; Sarkar, S; Thomas, B, 2000)
"Studies were performed to bring out a serotoninergic involvement in physostigmine tremor, hitherto known to be working via the cholinergic system."3.68Tremorogenesis by physostigmine is unrelated to acetylcholinesterase inhibition: evidence for serotoninergic involvement. ( Ganguly, DK; Mitra, N; Mohanakumar, KP, 1990)
"Clonidine exhibited a dose-dependent protection against harmine-induced tremors in mice."3.67Modification by clonidine of harmine-induced tremors in mice: involvement of serotoninergic system. ( Garg, SK; Kulkarni, SK; Shukla, VK, 1986)
"Amantadine was moderately effective, but cyproheptadine, diphenhydramine, and benztropine gave little or no relief."2.65Treatment of valproate tremors. ( Bauman, AW; Hammond, EJ; Karas, BJ; Wilder, BJ, 1983)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19906 (75.00)18.7374
1990's1 (12.50)18.2507
2000's1 (12.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Karas, BJ1
Wilder, BJ1
Hammond, EJ1
Bauman, AW1
Sarkar, S1
Thomas, B1
Muralikrishnan, D1
Mohanakumar, KP2
Nagao, T1
Ohshimo, T1
Mitsunobu, K1
Sato, M1
Otsuki, S1
Kulkarni, SK2
Kaul, PN1
Mitra, N1
Ganguly, DK1
Shukla, VK1
Garg, SK1
Vaupel, DB1
Martin, WR1
Achari, G1
Sinha, SP1

Trials

1 trial available for cyproheptadine and Tremor

ArticleYear
Treatment of valproate tremors.
    Neurology, 1983, Volume: 33, Issue:10

    Topics: Amantadine; Cyproheptadine; Diphenhydramine; Humans; Propranolol; Tremor; Valproic Acid

1983

Other Studies

7 other studies available for cyproheptadine and Tremor

ArticleYear
Effects of serotoninergic drugs on tremor induced by physostigmine in rats.
    Behavioural brain research, 2000, Volume: 109, Issue:2

    Topics: Animals; Buspirone; Cholinesterase Inhibitors; Cyproheptadine; Metergoline; N,N-Dimethyltryptamine;

2000
Cerebrospinal fluid monoamine metabolites and cyclic nucleotides in chronic schizophrenic patients with tardive dyskinesia or drug-induced tremor.
    Biological psychiatry, 1979, Volume: 14, Issue:3

    Topics: Adult; Chronic Disease; Cyclic AMP; Cyclic GMP; Cyproheptadine; Dyskinesia, Drug-Induced; Female; Ho

1979
Modification by levo-propranolol of tremors induced by harmine in mice.
    Experientia, 1979, Dec-15, Volume: 35, Issue:12

    Topics: Animals; Cyproheptadine; Dose-Response Relationship, Drug; Harmine; Male; Mice; Phenoxybenzamine; Pr

1979
Tremorogenesis by physostigmine is unrelated to acetylcholinesterase inhibition: evidence for serotoninergic involvement.
    Neuroscience letters, 1990, Nov-27, Volume: 120, Issue:1

    Topics: Acetylcholinesterase; Animals; Atropine; Caudate Nucleus; Cyproheptadine; Mecamylamine; Mesencephalo

1990
Modification by clonidine of harmine-induced tremors in mice: involvement of serotoninergic system.
    Archives internationales de pharmacodynamie et de therapie, 1986, Volume: 282, Issue:1

    Topics: Alkaloids; Animals; Clonidine; Cyproheptadine; Fluoxetine; Harmine; Male; Mice; Quipazine; Serotonin

1986
Interaction of oxotremorine with atropine, chlorpromazine, cyproheptadine, imipramine and phenoxybenzamine on the flexor reflex of the chronic spinal dog.
    Psychopharmacologia, 1973, Volume: 30, Issue:1

    Topics: Animals; Atropine; Chlorpromazine; Cyproheptadine; Dogs; Drug Interactions; Imipramine; Oxotremorine

1973
Tremor induced by tremorine (1,4-dipyrrolidino but-2-yne) and its antagonism by certain antihistaminics.
    Indian journal of physiology and pharmacology, 1967, Volume: 11, Issue:4

    Topics: Animals; Atropine; Cyproheptadine; Female; Histamine H1 Antagonists; Hydrochloric Acid; Male; Promet

1967