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cyproheptadine and Thrombosis

cyproheptadine has been researched along with Thrombosis in 5 studies

Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.

Thrombosis: Formation and development of a thrombus or blood clot in the blood vessel.

Research Excerpts

ExcerptRelevanceReference
"Changes in the coagulation system typical of consumption reaction, microthrombosis in the lungs and other organs and haemodynamic disturbances caused by infusion of endotoxin in weaned pigs were prevented by treatment with the serotonin receptor antagonist cyproheptadine."7.67Influence of cyproheptadine on endotoxin-induced disseminated intravascular coagulation (DIC) in weaned pigs. ( Markwardt, F; Nowak, G, 1985)
"Changes in the coagulation system typical of consumption reaction, microthrombosis in the lungs and other organs and haemodynamic disturbances caused by infusion of endotoxin in weaned pigs were prevented by treatment with the serotonin receptor antagonist cyproheptadine."3.67Influence of cyproheptadine on endotoxin-induced disseminated intravascular coagulation (DIC) in weaned pigs. ( Markwardt, F; Nowak, G, 1985)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19905 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
SELYE, H1
GABBIANI, G1
TUCHWEBER, B1
Bekemeier, H2
Hirschelmann, R2
Nowak, G1
Markwardt, F1
Giessler, AJ1
Danese, CA1
Haimov, M1

Other Studies

5 other studies available for cyproheptadine and Thrombosis

ArticleYear
EFFECT OF CYPROHEPTADINE UPON TWO FORMS OF THE THROMBOHEMORRHAGIC PHENOMENON (THP).
    Angiologica, 1965, Volume: 2

    Topics: Anaphylaxis; Cyproheptadine; Rats; Research; Shock; Shock, Hemorrhagic; Thrombosis

1965
Influence of serotonin, serotonin antagonists, some vasoactive substances and temperature on carrageenin-induced tail thrombosis in rats and mice.
    Agents and actions, 1986, Volume: 18, Issue:5-6

    Topics: Animals; Carrageenan; Cyproheptadine; Female; Male; Rats; Rats, Inbred Strains; Serotonin; Serotonin

1986
Influence of cyproheptadine on endotoxin-induced disseminated intravascular coagulation (DIC) in weaned pigs.
    Thrombosis and haemostasis, 1985, Apr-22, Volume: 53, Issue:2

    Topics: Animals; Cyproheptadine; Disseminated Intravascular Coagulation; Endotoxins; Escherichia coli; Femal

1985
Carrageenin-induced thrombosis in rats and mice: a model for testing antithrombotic substances?
    Agents and actions, 1985, Volume: 16, Issue:5

    Topics: Animals; Carrageenan; Cyproheptadine; Dibenzylchlorethamine; Disease Models, Animal; Dose-Response R

1985
Inhibition of experimental arterial thrombosis in dogs with platelet-deaggregating agents.
    Surgery, 1971, Volume: 70, Issue:6

    Topics: Administration, Oral; Animals; Aspirin; Blood Cell Count; Blood Platelets; Carotid Arteries; Cyprohe

1971